5j87 A 1.59 BS01 N42 A 1 L408 Q412 F413 V416 A428 K430 Y476 M477 A478 G480 C481 N526 L528 D539 L542 Y551 L13 Q17 F18 V21 A33 K35 Y81 M82 A83 G85 C86 N131 L133 D144 L147 Y156 D521 A523 R525 N526 D539 F559 D126 A128 R130 N131 D144 F164 2.7.10.2 0004672,0004713,0005524,0006468 -logKd/Ki=8.05, Ki=8.9nM EC50=<30nM, Ki=8.9nM, IC50=7.0nM Q06187 28315597 701 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 5j87 B 1.59 BS01 N42 B 1 L408 G411 F413 V416 A428 K430 Y476 M477 N479 G480 C481 N484 L528 D539 Y551 L24 G27 F29 V32 A44 K46 Y92 M93 N95 G96 C97 N100 L144 D155 Y167 D521 A523 R525 N526 D539 F559 D137 A139 R141 N142 D155 F175 2.7.10.2 0004672,0004713,0005524,0006468 EC50=<30nM, Ki=8.9nM, IC50=7.0nM Q06187 28315597 701 PSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 5j87 C 1.59 BS01 N42 C 1 L408 G409 Q412 V416 A428 K430 Y476 M477 N479 G480 C481 N484 L528 D539 L542 L13 G14 Q17 V21 A33 K35 Y81 M82 N84 G85 C86 N89 L133 D144 L147 D521 A523 R525 N526 D539 F559 D126 A128 R130 N131 D144 F164 2.7.10.2 0004672,0004713,0005524,0006468 EC50=<30nM, Ki=8.9nM, IC50=7.0nM Q06187 28315597 701 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMD 5j87 D 1.59 BS01 N42 D 1 L408 Q412 V416 A428 Y476 M477 A478 G480 C481 N484 L528 D539 L542 L13 Q17 V21 A33 Y81 M82 A83 G85 C86 N89 L133 D144 L147 D521 A523 R525 N526 D539 F559 D126 A128 R130 N131 D144 F164 2.7.10.2 0004672,0004713,0005524,0006468 EC50=<30nM, Ki=8.9nM, IC50=7.0nM Q06187 28315597 701 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE