1g9s B 2.8 BS01 N B 1 E403 I406 D407 S408 G409 N410 T411 L412 E91 I94 D95 S96 G97 N98 T99 L100 E403 D404 D407 F456 R469 E91 D92 D95 F144 R157 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006178,0016757,0032263,0032264,0032991,0042802,0046100,0046872,0051289,0052657,0097216 P0A9M2 12070315 490 MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSRDLKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILLD 1g9t B 2.8 BS01 N B 1 E403 D407 S408 G409 N410 T411 L412 E91 D95 S96 G97 N98 T99 L100 E403 D404 D407 F456 R469 E91 D92 D95 F144 R157 2.4.2.8 0000166,0000287,0004422,0005737,0005829,0006166,0006178,0016757,0032263,0032264,0032991,0042802,0046100,0046872,0051289,0052657,0097216 P0A9M2 12070315 490 MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSRDLKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILLD 1phw A 2.36 BS01 N A 1 P1115 A1116 F1117 K1138 R1168 H1202 P115 A116 F117 K138 R168 H202 N1026 K1060 D1250 N26 K60 D238 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0032991,0042802 Ki=0.5mM -logKd/Ki=3.30, Ki=0.5mM P0A715 16023668 70 MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK 1r15 A 2.4 BS01 N A 1 W77 S78 L97 S144 F174 E179 W77 S78 L97 S144 F174 E179 E98 F174 E179 E98 F174 E179 2.4.99.20,3.2.2.- 0003953,0005886,0007338,0016020,0016740,0016787,0016849,0030890,0031410,0061809 P29241 15016363 1179 IVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKDFFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGVYDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGFNEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGEKIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCSDNPNARECRLA 1r15 B 2.4 BS01 N B 1 W77 S78 L97 S144 F174 E179 W77 S78 L97 S144 F174 E179 E98 F174 E179 E98 F174 E179 2.4.99.20,3.2.2.- 0003953,0005886,0007338,0016020,0016740,0016787,0016849,0030890,0031410,0061809 P29241 15016363 1179 IVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKDFFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGVYDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGFNEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGEKIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCSDNPNARECRLA 1r15 C 2.4 BS01 N C 1 W77 S78 L97 S144 F174 E179 W77 S78 L97 S144 F174 E179 E98 F174 E179 E98 F174 E179 2.4.99.20,3.2.2.- 0003953,0005886,0007338,0016020,0016740,0016787,0016849,0030890,0031410,0061809 P29241 15016363 1179 IVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKDFFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGVYDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGFNEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGEKIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCSDNPNARECRLA 1r15 D 2.4 BS01 N D 1 W77 S78 L97 F174 E179 W77 S78 L97 F174 E179 E98 F174 E179 E98 F174 E179 2.4.99.20,3.2.2.- 0003953,0005886,0007338,0016020,0016740,0016787,0016849,0030890,0031410,0061809 P29241 15016363 1179 IVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKDFFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGVYDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGFNEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGEKIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCSDNPNARECRLA 1r15 E 2.4 BS01 N E 1 F76 W77 S78 L97 S144 F174 E179 F76 W77 S78 L97 S144 F174 E179 E98 F174 E179 E98 F174 E179 2.4.99.20,3.2.2.- 0003953,0005886,0007338,0016020,0016740,0016787,0016849,0030890,0031410,0061809 P29241 15016363 1179 IVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKDFFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGVYDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGFNEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGEKIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCSDNPNARECRLA 1r15 F 2.4 BS01 N F 1 F76 W77 S78 L97 F174 E179 F76 W77 S78 L97 F174 E179 E98 F174 E179 E98 F174 E179 2.4.99.20,3.2.2.- 0003953,0005886,0007338,0016020,0016740,0016787,0016849,0030890,0031410,0061809 P29241 15016363 1179 IVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKDFFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGVYDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGFNEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGEKIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCSDNPNARECRLA 1r15 G 2.4 BS01 N G 1 W77 S78 L97 F174 E179 W77 S78 L97 F174 E179 E98 F174 E179 E98 F174 E179 2.4.99.20,3.2.2.- 0003953,0005886,0007338,0016020,0016740,0016787,0016849,0030890,0031410,0061809 P29241 15016363 1179 IVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKDFFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGVYDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGFNEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGEKIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCSDNPNARECRLA 1r15 H 2.4 BS01 N H 1 W77 S78 L97 S144 F174 E179 W77 S78 L97 S144 F174 E179 E98 F174 E179 E98 F174 E179 2.4.99.20,3.2.2.- 0003953,0005886,0007338,0016020,0016740,0016787,0016849,0030890,0031410,0061809 P29241 15016363 1179 IVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKDFFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGVYDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGFNEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGEKIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCSDNPNARECRLA 1r16 A 2.0 BS01 N A 1 F76 W77 S78 L97 S144 S173 F174 E179 F76 W77 S78 L97 S144 S173 F174 E179 E98 F174 E179 E98 F174 E179 2.4.99.20,3.2.2.- 0003953,0005886,0007338,0016020,0016740,0016787,0016849,0030890,0031410,0061809 P29241 15016363 1179 IVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKDFFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGVYDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGFNEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGEKIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCSDNPNARECRLA 1r16 B 2.0 BS01 N B 1 W77 S78 L97 S173 F174 E179 W77 S78 L97 S173 F174 E179 E98 F174 E179 E98 F174 E179 2.4.99.20,3.2.2.- 0003953,0005886,0007338,0016020,0016740,0016787,0016849,0030890,0031410,0061809 P29241 15016363 1179 IVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKDFFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGVYDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGFNEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGEKIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCSDNPNARECRLA 3dzi B 1.73 BS01 N B 1 L124 W125 S126 R127 L145 S220 T221 F222 E226 L80 W81 S82 R83 L101 S176 T177 F178 E182 E146 T221 E226 E102 T177 E182 2.4.99.20,3.2.2.-,3.2.2.6 0061809 P28907 18940667 301 RWRQTWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCDITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFDTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLDGSRSKIFDKDSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSC 5z2v A 2.2 BS02 N A 1 E149 H153 H171 H189 E147 H151 H169 H187 ? 0003677,0006281,0006310,0046872 Q9I3H9 29633970 204 FSPLIRQLIESLRILPGVGQKSAQRMALMLLERDRSGGLKLAQALTAAMEGVGHCRQCRTLSEEELCPQCADPRRDDSLLCVVEGPLDVFAVEQTGYRGRYFVLKGHLSPLDGLGPEAIGIPELEARIRDGAFSEVILATNPTVEGEATAHYIAQLLAGRGLTLSRIAHGVPLGGELELVDGGTLAHALAGRRPI 8p2k Bv 2.9 BS02 N Bv 1 K47 R48 K42 R43 ? 0000470,0003723,0003735,0005737,0005840,0006412,0015934,0022625,1990904 G1SKZ8 37347872 302 SRDTLYEAVREVLHGNQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY 8u0z A 1.399 BS01 N A 1 A255 D257 K279 H281 Q433 Y435 G453 R454 A34 D36 K58 H60 Q212 Y214 G232 R233 2.4.2.10,4.1.1.23 0004590,0006207,0044205 A0A6P6VUE3 38184030 502 FRLPYGERVRLAKNPTGKKLFEIMIQKETNLCLAADVATAAELLDIADKVGPEICMLKTHVDILPDFTPDFGSKLRSIAEKHNFLIFEDRKFADIGNTVTMQYEGGIFKILDWADIVNAHIVSGPGIVDGLKLKGLPRGRGLLLLAEMSSSGNFAKGDYTAAAVKIAEGHSDFVIGFISVNPASWPSGPGNPALIHATPGVQLAKGGDALGQQYNTPFSVISERGSDIIIVGRGIIKAANPAEVAREYRLQGWDAYLLHC 8u0z B 1.399 BS01 N A 1 D315 T319 D94 T98 2.4.2.10,4.1.1.23 0004590,0006207,0044205 A0A6P6VUE3 38184030 502 FRLPYGERVRLAKNPTGKKLFEIMIQKETNLCLAADVATAAELLDIADKVGPEICMLKTHVDILPDFTPDFGSKLRSIAEKHNFLIFEDRKFADIGNTVTMQYEGGIFKILDWADIVNAHIVSGPGIVDGLKLKGLPRGRGLLLLAEMSSSGNFAKGDYTAAAVKIAEGHSDFVIGFISVNPASWPSGPGNPALIHATPGVQLQYNTPFSVISERGSDIIIVGRGIIKAANPAEVAREYRLQGWDAYLLHC