1phg A 1.6 BS02 MYT A 1 F87 Y96 F98 T185 L244 V247 G248 T252 V295 F78 Y87 F89 T176 L235 V238 G239 T243 V286 R186 G248 D251 T252 V253 C357 L358 G359 E366 V396 R177 G239 D242 T243 V244 C348 L349 G350 E357 V387 1.14.15.1 0004497,0005506,0005515,0005737,0016705,0018683,0019383,0020037,0046872 P00183 3442650 422 NLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPDLVWTRCNGGHWIATRGQLIREAYEDYRHFSSECPFIPREAGEAYDFIPTSMDPPEQRQFRALANQVVGMPVVDKLENRIQELACSLIESLRPQGQCNFTEDYAEPFPIRIFMLLAGLPEEDIPHLKYLTDQMTRPDGSMTFAEAKEALYDYLIPIIEQRRQKPGTDAISIVANGQVNGRPITSDEAKRMCGLLLVGGLDTVVNFLSFSMEFLAKSPEHRQELIERPERIPAACEELLRRFSLVADGRILTSDYEFHGVQLKKGDQILLPQMLSGLDERENACPMHVDFSRQKVSHTTFGHGSHLCLGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQALPLVWDPATTKAV 1w0g A 2.73 BS01 MYT A 1 R105 S119 A305 T309 A370 R81 S95 A262 T266 A327 T309 F435 C442 T266 F392 C399 1.14.14.1,1.14.14.55,1.14.14.56,1.14.14.73 0002933,0004497,0005496,0005506,0005515,0005737,0005783,0005789,0006629,0006631,0006694,0006706,0006805,0008202,0008203,0008209,0008210,0008395,0008401,0009822,0016020,0016098,0016491,0016705,0016712,0019825,0019899,0020037,0030343,0034875,0036378,0042178,0042359,0042369,0042572,0042573,0042759,0043231,0046222,0046872,0050591,0050649,0062181,0062187,0062188,0062189,0070330,0070576,0070989,0101020,0101021,0102320 IC50=3000nM P08684 15256616 1499 YGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDFLQLMIALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 4zf8 A 2.766 BS02 MYT A 1 L181 A264 T268 L181 A264 T268 T268 F393 C400 T268 F393 C400 1.14.14.1,1.6.2.4 0004497,0005506,0016705,0020037 P14779 27267136 502 TIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGLVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDIAGDGLVTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKQQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHVTTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLGGIPS 6ma6 A 2.182 BS02 MYT A 1 S119 A305 A370 S94 A274 A339 T309 F435 C442 T278 F404 C411 1.14.14.1,1.14.14.55,1.14.14.56,1.14.14.73 0002933,0004497,0005496,0005506,0005515,0005737,0005783,0005789,0006629,0006631,0006694,0006706,0006805,0008202,0008203,0008209,0008210,0008395,0008401,0009822,0016020,0016098,0016491,0016705,0016712,0019825,0019899,0020037,0030343,0034875,0036378,0042178,0042359,0042369,0042572,0042573,0042759,0043231,0046222,0046872,0050591,0050649,0062181,0062187,0062188,0062189,0070330,0070576,0070989,0101020,0101021,0102320 Kd=2.4uM IC50=3000nM P08684 30676743 603 GTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEQKHRVDFLQLMIDSQNSSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 7e7f A 1.4 BS02 MYT A 1 R110 F130 G314 T318 F487 I488 R80 F100 G284 T288 F457 I458 1.14.15.4 0004497,0004507,0005506,0005739,0005743,0006629,0006694,0006700,0006704,0006955,0008203,0008217,0016125,0016705,0020037,0032342,0032870,0034650,0034651,0035865,0042593,0046872,0047783,0071375,1901615 IC50=15nM P15538 34485929 602 VPRTVLPFEAMPRRPGNRRNRLNQIRREQGYEDLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSNSRNTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMFPLLTFRAI