1v4s A 2.3 BS02 MRK A 1 V62 R63 M210 I211 Y214 Y215 M235 V452 V455 V49 R50 M197 I198 Y201 Y202 M222 V439 V442 R85 S151 N166 D205 R72 S138 N153 D192 2.7.1.1 0001678,0004340,0004396,0005515,0005524,0005536,0005634,0005654,0005737,0005739,0005829,0005975,0006006,0006007,0006096,0006110,0006739,0008865,0009749,0016301,0016310,0016773,0019158,0019318,0032024,0032869,0042593,0043266,0044320,0045721,0045725,0046835,0050796,0051156,0061621,0070509,0141089,1901135 EC50=67.11nM, Kd=360nM P35557 15016359 501 TLVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKAC 3f9m A 1.5 BS02 MRK A 1 Y61 V62 R63 S64 T65 I211 Y214 Y215 M235 V452 V455 Y58 V59 R60 S61 T62 I204 Y207 Y208 M228 V445 V448 R85 S151 N166 K169 D205 R82 S144 N159 K162 D198 2.7.1.1 0001678,0004340,0004396,0005515,0005524,0005536,0005634,0005654,0005737,0005739,0005829,0005975,0006006,0006007,0006096,0006110,0006739,0008865,0009749,0016301,0016310,0016773,0019158,0019318,0032024,0032869,0042593,0043266,0044320,0045721,0045725,0046835,0050796,0051156,0061621,0070509,0141089,1901135 EC50=67.11nM, Kd=360nM P35557 22101819 501 ENLYFQGMKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACK 3id8 A 2.4 BS02 MRK A 1 V62 R63 S64 M210 I211 Y214 Y215 M235 V452 V455 V58 R59 S60 M203 I204 Y207 Y208 M228 V445 V448 R85 S151 N166 K169 D205 R81 S144 N159 K162 D198 2.7.1.1 0001678,0004340,0004396,0005515,0005524,0005536,0005634,0005654,0005737,0005739,0005829,0005975,0006006,0006007,0006096,0006110,0006739,0008865,0009749,0016301,0016310,0016773,0019158,0019318,0032024,0032869,0042593,0043266,0044320,0045721,0045725,0046835,0050796,0051156,0061621,0070509,0141089,1901135 EC50=67.11nM, Kd=360nM P35557 22101819 501 NLYFQGMKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVAC