1c39 A 1.85 BS02 M6P E 1 Y45 Q66 Y102 D103 N104 H105 R111 E133 R135 Y143 Y43 Q64 Y100 D101 N102 H103 R109 E131 R133 Y141 ? 0005768,0005794,0006622,0019904 P11456 10514470 3 EKTCDLVGEKGKESEKELALLKRLTPLFQKSFESTVGQSPDMYSYVFRVCREAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS 1c39 B 1.85 BS02 M6P F 1 Y45 Q66 Y102 D103 N104 H105 R111 E133 R135 Y143 Y43 Q64 Y100 D101 N102 H103 R109 E131 R133 Y141 ? 0005768,0005794,0006622,0019904 P11456 10514470 3 EKTCDLVGEKGKESEKELALLKRLTPLFQKSFESTVGQSPDMYSYVFRVCREAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS 1m6p A 1.8 BS02 M6P A 1 Y45 Q66 D103 N104 H105 R111 E133 R135 Y143 Y37 Q58 D95 N96 H97 R103 E125 R127 Y135 ? 0005768,0005794,0006622,0019904 Kd=8uM -logKd/Ki=5.10, Kd=8uM P11456 9604938 200 EKTCDLVGEKGKESEKELALLKRLTPLFQKSFESTMYSYVFRVCREAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS 1m6p B 1.8 BS01 M6P B 1 Y45 Q66 D103 N104 H105 R111 E133 R135 Y143 Y37 Q58 D95 N96 H97 R103 E125 R127 Y135 ? 0005768,0005794,0006622,0019904 Kd=8uM P11456 9604938 200 EKTCDLVGEKGKESEKELALLKRLTPLFQKSFESTMYSYVFRVCREAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS 1pcm X 1.9 BS02 M6P X 1 Y17 S108 T306 G307 H308 E325 S327 H329 R421 S423 Y9 S100 T298 G299 H300 E317 S319 H321 R413 S415 R20 S108 H109 K118 D242 D244 D246 R247 H329 D340 R12 S100 H101 K110 D234 D236 D238 R239 H321 D332 5.4.2.2,5.4.2.8 0000287,0004614,0004615,0005975,0009103,0009243,0009244,0009298,0016853,0016868,0042121,0046872 P26276 14725765 600 LPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGSHNPPDYNGFKIVVAGETLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAKPMKVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVFSAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF 1syo A 2.2 BS01 M6P A 1 Q348 C385 S386 R391 E416 C419 Y421 Q338 C375 S376 R381 E406 C409 Y411 ? 0005537,0007041,0038023 Kd~1nM -logKd/Ki=9.00, Kd~1nM P08169 15169779 500 AEFPELCSYTWEAVDTKNNMLYKINICGNMGVAQCGPSSAVCMHDLKTDSFHSVGDSLLKTASRSLLEFNTTVNCKQQNHKIQSSITFLCGKTLGTPEFVTATDCVHYFEWRTTAACKKNIFKANKEVPCYAFDRELKKHDLNPLIKTSGAYLVDDSDPDTSLFINVCRDIEVLRASSPQVRVCPTGAAACLVRGDRAFDVGRPQEGLKLVSNDRLVLSYVKEGAGQPDFCDGHSPAVTITFVCPSERREGTIPKLTAKSNCRFEIEWVTEYACHRDYLESRSCSLSSAQHDVAVDLQPLSRDSLFYTSEADEYTYYLSICGGSQAPICNKKDAAVCQVKKADSTQVKVAGRPQNLTLRYSDGDLTLIYFGGEECSSGFQRMSVINFECNQTAGNNGRGAPVFTGEVDCTYFFTWDTKYACV 1syo B 2.2 BS01 M6P B 1 Y1324 Q1348 C1385 S1386 R1391 E1416 C1419 Y1421 Y300 Q324 C361 S362 R367 E392 C395 Y397 ? 0005537,0007041,0038023 Kd~1nM -logKd/Ki=9.00, Kd~1nM P08169 15169779 1500 AEFPELCSYTWEAVDTKNNMLYKINICGNMGVAQCGPSSAVCMHDLKTDSFHSVGDSLLKTASRSLLEFNTTVNIQSSITFLCGKTLGTPEFVTATDCVHYFEWRTTAACKKNIFKANKEVPCYAFDRELKKHDLNPLIKTSGAYLVDDSDPDTSLFINVCRDIEVLRASSPQVRVCPTGAAACLVRGDRAFDVGRPQEGLKLVSNDRLVLSYVKFCDGHSPAVTITFVCPSERREGTIPKLTAKSNCRFEIEWVTEYACHRDYLESRSCSLSSAQHDVAVDLQPLSRVSLFYTSEADEYTYYLSICGGSQAPICNKKDAAVCQVKKADSTQVKVAGRPQNLTLRYSDGDLTLIYFGGEECSSGFQRMSVINFECNQTAGNNGRGAPVFTGEVDCTYFFTWDTKYACV 1sz0 A 2.1 BS01 M6P A 1 Y324 Q348 C385 S386 R391 E416 C419 Y421 Y309 Q333 C370 S371 R376 E401 C404 Y406 ? 0005537,0007041,0038023 Kd~1nM -logKd/Ki=9.00, Kd~1nM P08169 15169779 500 AEFPELCSYTWEAVDTKNNMLYKINICGNMGVAQCGPSSAVCMHDLKTDSFHSVGDSLLKTASRSLLEFNTTVNCKIQSSITFLCGKTLGTPEFVTATDCVHYFEWRTTAACKKNIFKANKEVPCYAFDRELKKHDLNPLIKTSGAYLVDDSDPDTSLFINVCRDIEVLRASSPQVRVCPTGAAACLVRGDRAFDVGRPQEGLKLVSNDRLVLSYVKEGAGQPDFCDGHSPAVTITFVCPSERREGTIPKLTAKSNCRFEIEWVTEYACHRDYLESRSCSLSSAQHDVAVDLQPLSSDSLFYTSEADEYTYYLSICGGSQAPICNKKDAAVCQVKKADSTQVKVAGRPQNLTLRYSDGDLTLIYFGGEECSSGFQRMSVINFECNQTAGNNGRGAPVFTGEVDCTYFFTWDTKYACV 1sz0 B 2.1 BS01 M6P B 1 Y1324 Q1348 C1385 S1386 R1391 E1416 C1419 Y1421 Y308 Q332 C369 S370 R375 E400 C403 Y405 ? 0005537,0007041,0038023 Kd~1nM -logKd/Ki=9.00, Kd~1nM P08169 15169779 1500 AEFPELCSYTWEAVDTKNNMLYKINICGNMGVAQCGPSSAVCMHDLKTDSFHSVGDSLLKTASRSLLEFNTTVNCKKIQSSITFLCGKTLGTPEFVTATDCVHYFEWRTTAACKKNIFKANKEVPCYAFDRELKKHDLNPLIKTSGAYLVDDSDPDTSLFINVCRDIEVLRASSPQVRVCPTGAAACLVRGDRAFDVGRPQEGLKLVSNDRLVLSYVKPDFCDGHSPAVTITFVCPSERREGTIPKLTAKSNCRFEIEWVTEYACHRDYLESRSCSLSSAQHDVAVDLQPLSRVASDSLFYTSEADEYTYYLSICGGSQAPICNKKDAAVCQVKKADSTQVKVAGRPQNLTLRYSDGDLTLIYFGGEECSSGFQRMSVINFECNQTAGNNGRGAPVFTGEVDCTYFFTWDTKYACV 2gc3 A 2.1 BS02 M6P A 1 Y52 T71 G87 H88 E97 A150 Y152 Y160 Y53 T72 G88 H89 E98 A151 Y153 Y161 5.3.1.9 0004347,0005506,0005737,0006094,0006096,0016853,0046872 P83194 16580686 501 MMYKEPFGVKVDFETGIIEGAKKSVRRLSDMEGYFVDERAWKELVEKEDPVVYEVYAVEQEEKEGDLNFATTVLYPGKVGKEFFFTKGHFHAKLDRAEVYVALKGKGGMLLQTPEGDAKWISMEPGTVVYVPPYWAHRTVNIGDEPFIFLAIYPADAGHDYGTIAEKGFSKIVIEENGEVKVVDNPRW 2gc3 B 2.1 BS02 M6P B 1 Y52 T71 G87 H88 E97 A150 H158 Y160 Y53 T72 G88 H89 E98 A151 H159 Y161 5.3.1.9 0004347,0005506,0005737,0006094,0006096,0016853,0046872 P83194 16580686 502 MMYKEPFGVKVDFETGIIEGAKKSVRRLSDMEGYFVDERAWKELVEKEDPVVYEVYAVEQEEKEGDLNFATTVLYPGKVGKEFFFTKGHFHAKLDRAEVYVALKGKGGMLLQTPEGDAKWISMEPGTVVYVPPYWAHRTVNIGDEPFIFLAIYPADAGHDYGTIAEKGFSKIVIEENGEVKVVDNPRW 2rl9 A 2.4 BS02 M6P C 1 Y45 Q66 Y102 D103 N104 H105 R111 E133 R135 Y143 Y37 Q58 Y94 D95 N96 H97 R103 E125 R127 Y135 ? 0005768,0005794,0006622,0019904 P11456 18272523 3 KTCDLVGEKGKESEKELALLKRLTPLFQKSFESTDMYSYVFRVCREAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS 2rl9 B 2.4 BS02 M6P D 1 Y45 Q66 Y102 D103 N104 H105 R111 E133 R135 Y143 Y42 Q63 Y99 D100 N101 H102 R108 E130 R132 Y140 ? 0005768,0005794,0006622,0019904 P11456 18272523 3 KTCDLVGEKGKESEKELALLKRLTPLFQKSFESTVGQSPDMYSYVFRVCREAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS 3c0o A 2.5 BS01 M6P A 1 A126 W127 R323 W324 R336 A125 W126 R322 W323 R335 ? 0005576,0016020,0020002,0035821,0042802,0090729 P09167 23912165 501 EPVYPDQLRLFSLGQGVCGDKYRPVNREEAQSVKSNIVGMMGQWQISGLANGWVIMGPGYNGEIKPGTASNTWCYPTNPVTGEIPTLSALDIPDGDEVDVQWRLVHDSANFIKPTSYLAHYLGYAWVGGNHSQYVGEDMDVTRDGDGWVIRGNNDGGCDGYRCGDKTAIKVSNFAYNLDPDSFKHGDVTQSDRQLVKTVVGWAVNDSDTPQSGYDVTLRGDTATNWSKTNTYGLSEKVTTKNKFKWPLVGETELSIEIAANQSWASQNGGSTTTSLSQSVRPTVPARSKIPVKIELYKADISYPYEFKADVSYDLTLSGFLRWGGNAWYTHPDNRPNWNHTFVIGPYKDKASSIRYQWDKRYIPGEVKWWDWNWTIQQNGLSTMQNNLARVLRPVRAGITGDFSAESQFAGNIEIGAPVPLGLRLEIPLDAQELSGLGFNNVSLSVTPAA 3c0o B 2.5 BS01 M6P B 1 W127 R323 W324 R336 W126 R322 W323 R335 ? 0005576,0016020,0020002,0035821,0042802,0090729 P09167 23912165 502 EPVYPDQLRLFSLGQGVCGDKYRPVNREEAQSVKSNIVGMMGQWQISGLANGWVIMGPGYNGEIKPGTASNTWCYPTNPVTGEIPTLSALDIPDGDEVDVQWRLVHDSANFIKPTSYLAHYLGYAWVGGNHSQYVGEDMDVTRDGDGWVIRGNNDGGCDGYRCGDKTAIKVSNFAYNLDPDSFKHGDVTQSDRQLVKTVVGWAVNDSDTPQSGYDVTLRGDTATNWSKTNTYGLSEKVTTKNKFKWPLVGETELSIEIAANQSWASQNGGSTTTSLSQSVRPTVPARSKIPVKIELYKADISYPYEFKADVSYDLTLSGFLRWGGNAWYTHPDNRPNWNHTFVIGPYKDKASSIRYQWDKRYIPGEVKWWDWNWTIQQNGLSTMQNNLARVLRPVRAGITGDFSAESQFAGNIEIGAPVPLGLRLEIPLDAQELSGLGFNNVSLSVTPAA 4r73 A 1.6 BS02 M6P A 1 R34 S37 G59 Y103 S148 G149 T150 G185 I186 H205 D206 E229 Q269 R36 S39 G61 Y105 S150 G151 T152 G187 I188 H207 D208 E231 Q271 ? 0015888,0030288,0030975,0030976 Kd=960nM A3N294 26295949 402 GSKGRLVIYCSATNVMCENAAKTFEQKYDVKTSFIRNGSGSTFAKIEAEKNNPQADVWYGGTLDPQSQAGELGLLEAYRSPNIDQIMPKFQDPAKVKGNLSSAVYIGILGFAVNTERLKKLGIEKIPQCWNDLTDPKLKGEIQIADPQSSGTAYTAIATFAQLWGEDKAFDYFKHLHPNISQYTKSGITPARNAARGETTVGIGFLHDYALEKEQGAPLEMVVPCEGTGYELGGVSILKGARNLDNAKLFVDFALSKEGQETAWKKGQALQTLTNTTAEQSPLAFDLTKLKLIDYDFEKYGASDERKRLINKWVDEIKLAK 4r73 B 1.6 BS02 M6P B 1 R34 S37 G59 Y103 S148 G149 T150 G185 I186 H205 D206 E229 R35 S38 G60 Y104 S149 G150 T151 G186 I187 H206 D207 E230 ? 0015888,0030288,0030975,0030976 Kd=960nM A3N294 26295949 402 SKGRLVIYCSATNVMCENAAKTFEQKYDVKTSFIRNGSGSTFAKIEAEKNNPQADVWYGGTLDPQSQAGELGLLEAYRSPNIDQIMPKFQDPAKVKGNLSSAVYIGILGFAVNTERLKKLGIEKIPQCWNDLTDPKLKGEIQIADPQSSGTAYTAIATFAQLWGEDKAFDYFKHLHPNISQYTKSGITPARNAARGETTVGIGFLHDYALEKEQGAPLEMVVPCEGTGYELGGVSILKGARNLDNAKLFVDFALSKEGQETAWKKGQALQTLTNTTAEQSPLAFDLTKLKLIDYDFEKYGASDERKRLINKWVDEIKLA 4rzc A 2.723 BS01 M6P A 1 T33 D95 I97 N98 T34 D100 I102 N103 26503547 201 ASQSVKESEGDLVKPGASLTLTCKASGFDFTWYTMNWVRQAPGKGLEWIASIGAGVYGSNYYASWAKGRFTISKASSTTVTLQMTSLTVADTATYFCARDGINGGYDIWGPGTLVTVSS 4rzc B 2.723 BS01 M6P A 1 R32 R95C R31 R95 26503547 201 LVMTQTESPVSAAGGTVTIKCQSSQSVYNNRLAWYQQKPGQRPKLLIYSASTLASGVPSRFKGSGSGTQFTLTISDLEWGDAATYYCHGGYRSDRYAFSGGTELEILSS 4rzc C 2.723 BS01 M6P C 1 Y32 T33 D95 G96 N98 Y31 T32 D98 G99 N101 26503547 201 QSVKESEGDLVKPGASLTLTCKASGFDFTWYTMNWVRQAPGKGLEWIASIGAGVYGSNYYASWAKGRFTISKASSTTVTLQMTSLTVADTATYFCARDGINGGYDIWGPGTLVTVSS 4rzc E 2.723 BS01 M6P E 1 T33 D95 G96 I97 N98 T32 D98 G99 I100 N101 26503547 201 QSVKESEGDLVKPGASLTLTCKASGFDFTWYTMNWVRQAPGKGLEWIASIGAGVYGSNYYASWAKGRFTISKASSTTVTLQMTSLTVADTATYFCARDGINGGYDIWGPGTLVTVSS 4rzc H 2.723 BS01 M6P H 1 W31 T33 D95 I97 N98 W31 T33 D99 I101 N102 26503547 201 SQSVKESEGDLVKPGASLTLTCKASGFDFTWYTMNWVRQAPGKGLEWIASIGAGVYGSNYYASWAKGRFTISKASSTTVTLQMTSLTVADTATYFCARDGINGGYDIWGPGTLVTVSS 4zev A 1.8 BS02 M6P A 1 L28 D29 T61 E152 T201 F202 Y205 L30 D31 T63 E154 T203 F204 Y207 3.8.1.- 0003824,0005737,0010323,0016311,0016787,0046872,0050308 Q8IJ74 26327372 302 HHMHEIVDKNGKKVQKNNLNDEIKIIFTALDGTLLNSENKVSEQNLESLIRAQEKGIKVVIATGRSIFSVENVIGEHVKKNRISLLPGIYMNGCVTFDEKGSRVIDRIMNNDLKMEIHEFSKQINISKYAIWFCLEKTYCFEINDCIREYMEVEALNPDVIEDNMLEGLTVYKVLFSLPENILENTLKLCREKFSHRINVANTFQSYVELFHQHTNKFEGVKEICKYYNISLNNALAMGDGENDIEMLSGLTHSVGVHNASEKVKNSAAYVGPSNNEHAISHVLKTFCDI 6np8 A 1.41 BS01 M6P A 1 Y9 R280 G302 H303 E320 S322 H324 R414 S416 N417 T418 R423 Y9 R280 G302 H303 E320 S322 H324 R414 S416 N417 T418 R423 R12 S97 H98 K107 D237 D239 D241 R242 H324 R12 S97 H98 K107 D237 D239 D241 R242 H324 0000287,0005975,0016868 31041362 501 MTLPAFKAYDIRGRVPDELNEDLARRIGVALAAQLDQGPVVLGHDVRLASPALQEALSAGLRASGRDVIDIGLCGTEEVYFQTDYLKAAGGVMVTASHNPMDYNGMKLVREQARPISSDTGLFAIRDTVAADTAAPGEPTASEQSRTDKTAYLEHLLSYVDRSTLKPLKLVVNAGNGGAGLIVDLLAPHLPFEFVRVFHEPDGNFPNGIPNPLLPENRDATAKAVKDNGADFGIAWDGDFDRCFFFDHTGRFIEGYYLVGLLAQAILAKQPGGKVVHDPRLTWNTVEQVEEAGGIPVLCKSGHAFIKEKMRSENAVYGGEMSAHHYFREFAYADSGMIPWLLIAELVSQSGRSLADLVEARMQKFPCSGEINFKVADAKASVARVMEHYASLSPELDYTDGISADFGQWRFNLRSSNTEPLLRLNVETRGDAALLETRTQEISNLLRG 6npx A 1.42 BS02 M6P A 1 R280 G302 H303 E320 S322 H324 R414 S416 N417 T418 R423 R280 G302 H303 E320 S322 H324 R414 S416 N417 T418 R423 R12 S97 H98 K107 D237 D239 D241 R242 H324 R12 S97 H98 K107 D237 D239 D241 R242 H324 0000287,0005975,0016868 31041362 503 MTLPAFKAYDIRGRVPDELNEDLARRIGVALAAQLDQGPVVLGHDVRLASPALQEALSAGLRASGRDVIDIGLCGTEEVYFQTDYLKAAGGVMVTASHNPMDYNGMKLVREQARPISSDTGLFAIRDTVAADTAAPGEPTASEQSRTDKTAYLEHLLSYVDRSTLKPLKLVVNAGNGGAGLIVDLLAPHLPFEFVRVFHEPDGNFPNGIPNPLLPENRDATAKAVKDNGADFGIAWDGDFDRCFFFDHTGRFIEGYYLVGLLAQAILAKQPGGKVVHDPRLTWNTVEQVEEAGGIPVLCKSGHAFIKEKMRSENAVYGGEMSAHHYFREFAYADSGMIPWLLIAELVSQSGRSLADLVEARMQKFPCSGEINFKVADAKASVARVMEHYASLSPELDYTDGISADFGQWRFNLRSSNTEPLLRLNVETRGDAALLETRTQEISNLLRG 6pki A 2.293 BS01 M6P A 1 S37 T269 G297 R325 S2 T234 G262 R290 ? F1QSF9 32109365 404 GSGPYTKSHGPSHSHRYVRDSQPVAHGTVTHETQAASKHSNSPVLESNIFISDITDDSGTHRWVSGHITEVHDPLRSVSVLEPGGPGGCAHNHRELVEVTAKTRKCLVAQNGGYFDTHTGQCLGNIISDGKLVRNSGGIQNAQFGIRKDGTLVFGYLSEDDILDQENPFVQLISGVVWLLRKGEIYINESIQAESDKTQETGNFRHFVDVISARTAVGHDKEGKLILFHVDGQTDVRGMNLWQVAKFLKDQNVMNAINLDGGGSATYVLNGSLASYPSDHCNPSKWRCPRAISTVLCIHER 6pki B 2.293 BS01 M6P B 1 S37 T269 R325 S2 T231 R287 ? F1QSF9 32109365 404 GSGPYTKSHGPSHSHRYVRDSQPVAHGTVTHETQAASKHSNSPVLESNIFISDITDDSGTHRWVSGHITEVHDPLRSVSVLEPGGPGGCAHNHRELVEVTAKTRKCLVAQNGGYFDTHTGQCLGNIISDGKLVRNSGGIQNAQFGIRKDGTLVFGYLSEDDILDQENPFVQLISGVVWLLRKGEIYINESIQAESDKTGNFRHFVDVISARTAVGHDKEGKLILFHVDGQTDVRGMNLWQVAKFLKDQNVMNAINLDGGGSATYVLNGSLASYPSDHCNPSKWRCPRAISTVLCIHER 6pki C 2.293 BS01 M6P C 1 S37 T269 G297 R325 S2 T231 G259 R287 ? F1QSF9 32109365 404 GSGPYTKSHGPSHSHRYVRDSQPVAHGTVTHETQAASKHSNSPVLESNIFISDITDDSGTHRWVSGHITEVHDPLRSVSVLEPGGPGGCAHNHRELVEVTAKTRKCLVAQNGGYFDTHTGQCLGNIISDGKLVRNSGGIQNAQFGIRKDGTLVFGYLSEDDILDQENPFVQLISGVVWLLRKGEIYINESIQAESDKTGNFRHFVDVISARTAVGHDKEGKLILFHVDGQTDVRGMNLWQVAKFLKDQNVMNAINLDGGGSATYVLNGSLASYPSDHCNPSKWRCPRAISTVLCIHER 6pki C 2.293 BS02 M6P C 2 K281 K284 D285 K243 K246 D247 ? F1QSF9 32109365 405 GSGPYTKSHGPSHSHRYVRDSQPVAHGTVTHETQAASKHSNSPVLESNIFISDITDDSGTHRWVSGHITEVHDPLRSVSVLEPGGPGGCAHNHRELVEVTAKTRKCLVAQNGGYFDTHTGQCLGNIISDGKLVRNSGGIQNAQFGIRKDGTLVFGYLSEDDILDQENPFVQLISGVVWLLRKGEIYINESIQAESDKTGNFRHFVDVISARTAVGHDKEGKLILFHVDGQTDVRGMNLWQVAKFLKDQNVMNAINLDGGGSATYVLNGSLASYPSDHCNPSKWRCPRAISTVLCIHER 6pki D 2.293 BS01 M6P D 1 S37 T269 G297 R325 S2 T229 G257 R285 ? F1QSF9 32109365 404 GSGPYTKSHGPSHSHRYVRDSQPVAHGTVTHETQAASKHSNSPVLESNIFISDITDDSGTHRWVSGHITEVHDPLRSVSVLEPGGPGGCAHNHRELVEVTAKTRKCLVAQNGGYFDTHTGQCLGNIISDGKLVRNSGGIQNAQFGIRKDGTLVFGYLSEDDILDQENPFVQLISGVVWLLRKGEIYINESIQAESDGNFRHFVDVISARTAVGHDKEGKLILFHVDGQTDVRGMNLWQVAKFLKDQNVMNAINLDGGGSATYVLNGSLASYPSDHCNPSKWRCPRAISTVLCIHER 6pku A 1.949 BS01 M6P A 1 T260 G288 G289 R316 T196 G224 G225 R252 ? H0VTT5 32109365 402 LKHENWPPPGPPAVRTFVSHFGGRAVSGHLTRAAAPLRTFSVLEPGGPGGCSQKRRATVEETAQAAACRIAQNGGFFRMNTGECLGNVVSDGRRVSSSGGLQNAQFGIRRDGTLVTGYLSEEEVLDTENPFVQLLSGVVWLIRNGSIYINESQATESDETQETGSFSKFVNVMSARTAIGHDRDGQLVLFHADGQTEQRGINLWEMAEFLLRQGVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRRVSTVVCVHEP 6pku B 1.949 BS01 M6P B 1 T260 G289 R316 T197 G226 R253 ? H0VTT5 32109365 403 LKHENWPPPPGPPAVRTFVSHFGGRAVSGHLTRAAAPLRTFSVLEPGGPGGCSQKRRATVEETAQAAACRIAQNGGFFRMNTGECLGNVVSDGRRVSSSGGLQNAQFGIRRDGTLVTGYLSEEEVLDTENPFVQLLSGVVWLIRNGSIYINESQATESDETQETGSFSKFVNVMSARTAIGHDRDGQLVLFHADGQTEQRGINLWEMAEFLLRQGVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRRVSTVVCVHEP 6pku C 1.949 BS01 M6P C 1 T260 G289 R316 T196 G225 R252 ? H0VTT5 32109365 402 LKHENWPPPGPPAVRTFVSHFGGRAVSGHLTRAAAPLRTFSVLEPGGPGGCSQKRRATVEETAQAAACRIAQNGGFFRMNTGECLGNVVSDGRRVSSSGGLQNAQFGIRRDGTLVTGYLSEEEVLDTENPFVQLLSGVVWLIRNGSIYINESQATESDETQETGSFSKFVNVMSARTAIGHDRDGQLVLFHADGQTEQRGINLWEMAEFLLRQGVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRRVSTVVCVHEP 6pku D 1.949 BS01 M6P D 1 T260 G289 R316 T196 G225 R252 ? H0VTT5 32109365 402 LKHENWPPPGPPAVRTFVSHFGGRAVSGHLTRAAAPLRTFSVLEPGGPGGCSQKRRATVEETAQAAACRIAQNGGFFRMNTGECLGNVVSDGRRVSSSGGLQNAQFGIRRDGTLVTGYLSEEEVLDTENPFVQLLSGVVWLIRNGSIYINESQATESDETQETGSFSKFVNVMSARTAIGHDRDGQLVLFHADGQTEQRGINLWEMAEFLLRQGVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRRVSTVVCVHEP 7kma A 2.7 BS01 M6P A 1 Y130 S131 R132 G196 A197 E198 N208 K209 K234 Y122 S123 R124 G188 A189 E190 N200 K201 K226 ? 0002183,0003743,0005085,0005515,0005737,0005829,0005851,0005886,0006412,0006413,0009408,0009749,0014003,0016020,0042802,0043434,0044237,0050852 Q14232 34103529 401 DDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKDLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYLG 7kma B 2.7 BS01 M6P B 1 Y130 S131 R132 V133 E198 N208 K234 Y104 S105 R106 V107 E172 N182 K208 ? 0002183,0003743,0005085,0005515,0005737,0005829,0005851,0005886,0006412,0006413,0009408,0009749,0014003,0016020,0042802,0043434,0044237,0050852 Q14232 34103529 401 KELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRANLTSAIETLCGVDSSVAVSSGGELFLRFISKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYLG 7kma C 2.7 BS01 M6P C 1 Y130 S131 R132 V133 G196 E198 N208 K209 K234 Y130 S131 R132 V133 G196 E198 N208 K209 K234 ? 0002183,0003743,0005085,0005515,0005737,0005829,0005851,0005886,0006412,0006413,0009408,0009749,0014003,0016020,0042802,0043434,0044237,0050852 Q14232 34103529 401 MDDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISLASLEYSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKAKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYLG 7kma D 2.7 BS01 M6P D 1 Y130 S131 R132 G196 A197 E198 N208 K234 Y120 S121 R122 G186 A187 E188 N198 K224 ? 0002183,0003743,0005085,0005515,0005737,0005829,0005851,0005886,0006412,0006413,0009408,0009749,0014003,0016020,0042802,0043434,0044237,0050852 Q14232 34103529 401 MDDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDETIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYLG 7kma E 2.7 BS01 M6P E 1 Y130 S131 R132 V133 G196 E198 N208 K234 Y117 S118 R119 V120 G183 E185 N195 K221 ? 0002183,0003743,0005085,0005515,0005737,0005829,0005851,0005886,0006412,0006413,0009408,0009749,0014003,0016020,0042802,0043434,0044237,0050852 Q14232 34103529 401 DKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISLDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYL 7kma F 2.7 BS01 M6P F 1 Y130 S131 R132 G196 A197 E198 N208 Y124 S125 R126 G190 A191 E192 N202 ? 0002183,0003743,0005085,0005515,0005737,0005829,0005851,0005886,0006412,0006413,0009408,0009749,0014003,0016020,0042802,0043434,0044237,0050852 Q14232 34103529 401 MDDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYLG 7kma G 2.7 BS01 M6P G 1 Y130 S131 R132 V133 E198 N208 K234 Y128 S129 R130 V131 E196 N206 K232 ? 0002183,0003743,0005085,0005515,0005737,0005829,0005851,0005886,0006412,0006413,0009408,0009749,0014003,0016020,0042802,0043434,0044237,0050852 Q14232 34103529 401 MDDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISLASLEYSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYLG 7kma H 2.7 BS01 M6P H 1 Y130 S131 R132 G196 A197 E198 N208 K209 K234 Y128 S129 R130 G194 A195 E196 N206 K207 K232 ? 0002183,0003743,0005085,0005515,0005737,0005829,0005851,0005886,0006412,0006413,0009408,0009749,0014003,0016020,0042802,0043434,0044237,0050852 Q14232 34103529 401 MDDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDETIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISLASLEYSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKAHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYLG