1uu3 A 1.7 BS01 LY4 A 1 L88 G89 A109 K111 V143 L159 S160 Y161 A162 G165 E166 E209 L212 T222 D223 L16 G17 A37 K39 V71 L87 S88 Y89 A90 G93 E94 E137 L140 T150 D151 D205 K207 E209 N210 D223 T245 D133 K135 E137 N138 D151 T163 2.7.11.1 0004672,0004674,0005524,0006468 ic50=0.75uM -logKd/Ki=6.12, IC50=0.75uM Kd=700nM, IC50=750nM O15530 14962382 1374 QPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT 2j2i B 1.9 BS01 LY4 B 1 L44 F49 V52 A65 L120 E121 R122 V126 D128 E171 L174 D186 L12 F17 V20 A33 L88 E89 R90 V94 D96 E139 L142 D154 N172 D186 L193 N140 D154 L161 2.7.11.1 0004672,0004674,0005515,0005524,0005634,0005654,0005730,0005737,0005829,0005886,0006338,0006468,0006915,0008134,0016310,0022898,0030145,0043024,0043066,0043433,0044024,0045824,0045893,0046777,0046872,0050821,0060045,0070561,0071346,0090336,0106310,1902033,1904263,1905062,1990748 ic50=0.2uM -logKd/Ki=6.70, IC50=200nM Kd=270nM, IC50=200nM P11309 18077363 1307 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH