2euf B 3.0 BS01 LQQ B 1 I19 F98 E99 V101 D102 Q103 D104 T107 L152 A162 D163 I10 F89 E90 V92 D93 Q94 D95 T98 L143 A153 D154 D145 K147 Q149 N150 D163 A175 T182 D136 K138 Q140 N141 D154 A166 T173 2.7.11.22 0000082,0000122,0000307,0001726,0001954,0002244,0003323,0004672,0004674,0004693,0005515,0005524,0005634,0005654,0005737,0005813,0005829,0005856,0006468,0007165,0007219,0008285,0009615,0010389,0010468,0010628,0014002,0016301,0016310,0021542,0021670,0030097,0030154,0030332,0033077,0042063,0042127,0042995,0043697,0045596,0045638,0045646,0045656,0045668,0045786,0048146,0048699,0050680,0051301,0051726,0060218,0097131,0097132,0097133,0098770,0106310,1902036,2000145,2000773 -logKd/Ki=7.82, IC50=15nM IC50=16nM, Ki=27nM Q00534 16789739 401 DQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLER 5l2i A 2.75 BS01 LQQ A 1 I19 A41 F98 V101 T107 Q149 L152 D163 I10 A32 F73 V76 T82 Q124 L127 D138 D145 K147 Q149 N150 D163 T182 D120 K122 Q124 N125 D138 T143 2.7.11.22 0000082,0000122,0000307,0001726,0001954,0002244,0003323,0004672,0004674,0004693,0005515,0005524,0005634,0005654,0005737,0005813,0005829,0005856,0006468,0007165,0007219,0008285,0009615,0010389,0010468,0010628,0014002,0016301,0016310,0021542,0021670,0030097,0030154,0030332,0033077,0042063,0042127,0042995,0043697,0045596,0045638,0045646,0045656,0045668,0045786,0048146,0048699,0050680,0051301,0051726,0060218,0097131,0097132,0097133,0098770,0106310,1902036,2000145,2000773 -logKd/Ki=7.40, Kd=40.1nM IC50=16nM, Ki=27nM Q00534 27496135 900 DQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRPLSTIREVAVLRHLETFEHPNVVRLFDVCTKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQ 7n7o A 2.7 BS01 LQQ A 1 F134 I143 T196 N198 V199 F200 T232 I358 D359 F95 I104 T157 N159 V160 F161 T193 I279 D280 2.7.1.149 0001750,0001917,0005515,0005524,0005634,0005654,0005737,0005764,0005776,0005829,0005886,0006629,0010506,0016301,0016308,0016309,0016310,0035855,0042803,0042995,0046488,0046627,0046854,0052742,0061909,0090119,1902635,2000786 P48426 34001596 501 SDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSRFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERALAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHVNPEQYSKRFLDFIGHIL