1gzg A 1.66 BS01 LAF A 1 D131 N139 S175 K205 R215 K229 K260 D125 N133 S169 K199 R209 K223 K254 K205 K260 K199 K254 4.2.1.24 0004655,0005829,0006779,0006782,0006783,0008270,0016829,0033014,0046872 Q59643 12079382 1336 NRAYPYTRLRRNRRDDFSRRLVRENVLTVDDLILPVFVLDGVNQRESIPSMPGVERLSIDQLLIEAEEWVALGIPALALFPVTPVEKKSLDAAEAYNPEGIAQRATRALRERFPELGIITDVALDPFTTHGQNGILDDDGYVLNDVSIDVLVRQALSHAEAGAQVVAPSDMMDGRIGAIREALESAGHTNVRVMAYSAKYASAYYGPFRDAVGSASNLGKGNKATYQMDPANSDEALHEVAADLAEGADMVMVKPGMPYLDIVRRVKDEFRAPTFVYQVSGEYAMHMGAIQNGWLAESVILESLTAFKRAGADGILTYFAKQAAEQLRR 1gzg A 1.66 BS02 LAF A 2 F86 S175 Y211 F214 K260 Y283 V285 S286 Y324 F80 S169 Y205 F208 K254 Y277 V279 S280 Y318 K205 K260 K199 K254 4.2.1.24 0004655,0005829,0006779,0006782,0006783,0008270,0016829,0033014,0046872 Q59643 12079382 1337 NRAYPYTRLRRNRRDDFSRRLVRENVLTVDDLILPVFVLDGVNQRESIPSMPGVERLSIDQLLIEAEEWVALGIPALALFPVTPVEKKSLDAAEAYNPEGIAQRATRALRERFPELGIITDVALDPFTTHGQNGILDDDGYVLNDVSIDVLVRQALSHAEAGAQVVAPSDMMDGRIGAIREALESAGHTNVRVMAYSAKYASAYYGPFRDAVGSASNLGKGNKATYQMDPANSDEALHEVAADLAEGADMVMVKPGMPYLDIVRRVKDEFRAPTFVYQVSGEYAMHMGAIQNGWLAESVILESLTAFKRAGADGILTYFAKQAAEQLRR 1gzg B 1.66 BS01 LAF B 1 S175 K205 R215 K229 Q233 S171 K201 R211 K217 Q221 K205 K260 K201 K248 4.2.1.24 0004655,0005829,0006779,0006782,0006783,0008270,0016829,0033014,0046872 -logKd/Ki=3.05, IC50=0.9mM Q59643 12079382 1338 PANRAYPYTRLRRNRRDDFSRRLVRENVLTVDDLILPVFVLDGVNQRESIPSMPGVERLSIDQLLIEAEEWVALGIPALALFPVTPVEKKSLDAAEAYNPEGIAQRATRALRERFPELGIITDVALDPFTTHGQNGILDDDGYVLNDVSIDVLVRQALSHAEAGAQVVAPSDMMDGRIGAIREALESAGHTNVRVMAYSAKYASAYYGPFRDAVGSKATYQMDPANSDEALHEVAADLAEGADMVMVKPGMPYLDIVRRVKDEFRAPTFVYQVSGEYAMHMGAIQNGWLAESVILESLTAFKRAGADGILTYFAKQAAEQLRR 1gzg B 1.66 BS02 LAF B 2 Y211 F214 K260 Y283 V285 S286 Y324 Y207 F210 K248 Y271 V273 S274 Y312 K205 K260 K201 K248 4.2.1.24 0004655,0005829,0006779,0006782,0006783,0008270,0016829,0033014,0046872 -logKd/Ki=3.05, IC50=0.9mM Q59643 12079382 1337 PANRAYPYTRLRRNRRDDFSRRLVRENVLTVDDLILPVFVLDGVNQRESIPSMPGVERLSIDQLLIEAEEWVALGIPALALFPVTPVEKKSLDAAEAYNPEGIAQRATRALRERFPELGIITDVALDPFTTHGQNGILDDDGYVLNDVSIDVLVRQALSHAEAGAQVVAPSDMMDGRIGAIREALESAGHTNVRVMAYSAKYASAYYGPFRDAVGSKATYQMDPANSDEALHEVAADLAEGADMVMVKPGMPYLDIVRRVKDEFRAPTFVYQVSGEYAMHMGAIQNGWLAESVILESLTAFKRAGADGILTYFAKQAAEQLRR