6npu A 2.33 BS02 KWV A 1 A356 L359 L360 A452 Y454 E481 G482 P484 V487 A101 L104 L105 A197 Y199 E226 G227 P229 V232 D382 A384 R386 N387 D400 P421 D127 A129 R131 N132 D145 P166 2.7.10.2 0004672,0004713,0005524,0006468 ic50=0.00000001M -logKd/Ki=6.40, IC50=0.40uM IC50=398nM, EC50=794nM P00519 30689376 602 YDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES 6npu B 2.33 BS02 KWV B 1 L360 I451 A452 Y454 E481 G482 P484 V487 L103 I179 A180 Y182 E209 G210 P212 V215 D382 A384 R386 N387 D400 P421 D125 A127 R129 N130 D143 P149 2.7.10.2 0004672,0004713,0005524,0006468 ic50=0.00000001M IC50=398nM, EC50=794nM P00519 30689376 605 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKEL