4pni A 1.85 BS01 KQQ A 1 L193 F198 V201 A214 T265 M267 N268 G270 D271 L321 R474 T475 L164 F169 V172 A185 T236 M238 N239 G241 D242 L292 R445 T446 D314 K316 E318 N319 D332 A341 T352 D285 K287 E289 N290 D303 A312 T323 2.7.11.14 0001750,0004672,0004674,0004703,0005515,0005524,0005737,0006468,0007165,0007601,0009966,0016020,0016310,0022400,0042995,0046777,0050254,0097381 ic50=0.125uM -logKd/Ki=6.09, IC50=0.81uM IC50=130nM P28327 25238254 601 SRDRKYLARLKLPPLSKCEALRESLDLGFEGMCLEQPIGKRLFQQFLRTHEQHGPALQLWKDIEDYDTADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAGAGDGLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQPMGEDWFLDFRVLGRGGFGEVFACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQRNIIYRDLKPENVLLDDDGNVRISDLGLAVELKAGQTKTKGYAGTPGFMAPELLLGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKNIAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRP