3a5y A 1.9 BS01 KAA A 1 S76 E78 R100 H108 N109 F112 M114 Y118 E244 L245 N247 F249 E251 G296 A298 G300 R303 S72 E74 R96 H104 N105 F108 M110 Y114 E216 L217 N219 F221 E223 G268 A270 G272 R275 6.3.1.- 0000049,0000166,0004812,0004824,0005515,0005524,0005737,0005829,0006418,0006430,0016874,0016880,0042803,0043687,0052868,0071468,0071915 Kd=11nM -logKd/Ki=7.96, Kd=11nM P0A8N7 20729861 1990 ASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA 3a5y B 1.9 BS01 KAA B 1 S76 E78 R100 H108 N109 F112 M114 Y118 E244 L245 A246 N247 F249 E251 G296 A298 G300 R303 S74 E76 R98 H106 N107 F110 M112 Y116 E229 L230 A231 N232 F234 E236 G281 A283 G285 R288 6.3.1.- 0000049,0000166,0004812,0004824,0005515,0005524,0005737,0005829,0006418,0006430,0016874,0016880,0042803,0043687,0052868,0071468,0071915 Kd=11nM -logKd/Ki=7.96, Kd=11nM P0A8N7 20729861 1991 ETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA 3a5y C 1.9 BS01 KAA C 1 E78 R100 H108 N109 F112 M114 Y118 E244 L245 A246 N247 F249 E251 G296 A298 G300 R303 E71 R93 H101 N102 F105 M107 Y111 E231 L232 A233 N234 F236 E238 G283 A285 G287 R290 6.3.1.- 0000049,0000166,0004812,0004824,0005515,0005524,0005737,0005829,0006418,0006430,0016874,0016880,0042803,0043687,0052868,0071468,0071915 Kd=11nM P0A8N7 20729861 1992 TASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA 3a5y D 1.9 BS01 KAA D 1 E78 R100 H108 N109 F112 M114 Y118 E244 L245 A246 N247 F249 E251 G296 A298 G300 R303 E68 R90 H98 N99 F102 M104 Y108 E230 L231 A232 N233 F235 E237 G282 A284 G286 R289 6.3.1.- 0000049,0000166,0004812,0004824,0005515,0005524,0005737,0005829,0006418,0006430,0016874,0016880,0042803,0043687,0052868,0071468,0071915 Kd=11nM P0A8N7 20729861 1993 TASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA 3a5z A 2.5 BS01 KAA A 1 E78 R100 H108 N109 F112 M114 Y118 E244 L245 N247 F249 E251 G300 E76 R98 H106 N107 F110 M112 Y116 E242 L243 N245 F247 E249 G298 6.3.1.- 0000049,0000166,0004812,0004824,0005515,0005524,0005737,0005829,0006418,0006430,0016874,0016880,0042803,0043687,0052868,0071468,0071915 P0A8N7 20729861 990 ETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA 3a5z C 2.5 BS01 KAA C 1 E78 R100 H108 N109 F112 M114 Y118 E244 L245 N247 F249 E251 G296 A298 G300 R303 E77 R99 H107 N108 F111 M113 Y117 E243 L244 N246 F248 E250 G295 A297 G299 R302 6.3.1.- 0000049,0000166,0004812,0004824,0005515,0005524,0005737,0005829,0006418,0006430,0016874,0016880,0042803,0043687,0052868,0071468,0071915 P0A8N7 20729861 991 SETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA 3a5z E 2.5 BS01 KAA E 1 E78 R100 N109 F112 M114 E244 L245 N247 F249 E251 G296 G300 R303 E76 R98 N107 F110 M112 E242 L243 N245 F247 E249 G294 G298 R301 6.3.1.- 0000049,0000166,0004812,0004824,0005515,0005524,0005737,0005829,0006418,0006430,0016874,0016880,0042803,0043687,0052868,0071468,0071915 P0A8N7 20729861 992 ETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA 3a5z G 2.5 BS01 KAA G 1 E78 R100 E103 H108 N109 F112 M114 Y118 E244 L245 N247 F249 E251 G296 A298 G300 E76 R98 E101 H106 N107 F110 M112 Y116 E242 L243 N245 F247 E249 G294 A296 G298 6.3.1.- 0000049,0000166,0004812,0004824,0005515,0005524,0005737,0005829,0006418,0006430,0016874,0016880,0042803,0043687,0052868,0071468,0071915 P0A8N7 20729861 993 MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA 3e9h A 2.1 BS02 KAA A 1 E231 R253 H261 N262 F265 M267 E269 Y271 E411 H412 N414 F416 E418 G463 G467 R470 E223 R245 H253 N254 F257 M259 E261 Y263 E403 H404 N406 F408 E410 G455 G459 R462 R253 E255 R260 H261 E411 N414 R470 R245 E247 R252 H253 E403 N406 R462 6.1.1.6 0000049,0000166,0000287,0003676,0004812,0004824,0005524,0005737,0005829,0006412,0006418,0006430,0016740,0046872 -logKd/Ki=7.55, Ki=28nM Q9RHV9 19174549 2002 ELNDQLRVRREKLKKIEELGVDPFGKRFERTHKAEELFELYGDLSKEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQDDVGEQQYELFKISDLGDIVGVRGTMFKTKVGELSIKVSSYEFLTKALRPLPEKDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMMHAVAGGAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGISTRHNPEFTMLELYEAYADFRDIMKLTENLIAHIATEVLGTTKIQYGEHLVDLTPEWRRLHMVDAIKEYVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKEREQGNDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRH 3e9h B 2.1 BS02 KAA B 1 G207 E231 R253 H261 N262 F265 M267 E269 Y271 E411 H412 N414 F416 E418 G467 R470 G199 E223 R245 H253 N254 F257 M259 E261 Y263 E403 H404 N406 F408 E410 G459 R462 R253 E255 R260 H261 E411 N414 R470 R245 E247 R252 H253 E403 N406 R462 6.1.1.6 0000049,0000166,0000287,0003676,0004812,0004824,0005524,0005737,0005829,0006412,0006418,0006430,0016740,0046872 Q9RHV9 19174549 2003 ELNDQLRVRREKLKKIEELGVDPFGKRFERTHKAEELFELYGDLSKEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQDDVGEQQYELFKISDLGDIVGVRGTMFKTKVGELSIKVSSYEFLTKALRPLPEKDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMMHAVAGGAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGISTRHNPEFTMLELYEAYADFRDIMKLTENLIAHIATEVLGTTKIQYGEHLVDLTPEWRRLHMVDAIKEYVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKEREQGNDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRH 3e9h C 2.1 BS02 KAA C 1 E231 R253 H261 N262 F265 M267 E269 Y271 E411 H412 N414 F416 E418 G463 G467 R470 E223 R245 H253 N254 F257 M259 E261 Y263 E403 H404 N406 F408 E410 G455 G459 R462 R253 E255 R260 H261 E411 N414 R470 R245 E247 R252 H253 E403 N406 R462 6.1.1.6 0000049,0000166,0000287,0003676,0004812,0004824,0005524,0005737,0005829,0006412,0006418,0006430,0016740,0046872 Q9RHV9 19174549 2004 ELNDQLRVRREKLKKIEELGVDPFGKRFERTHKAEELFELYGDLSKEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQDDVGEQQYELFKISDLGDIVGVRGTMFKTKVGELSIKVSSYEFLTKALRPLPEKDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMMHAVAGGAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGISTRHNPEFTMLELYEAYADFRDIMKLTENLIAHIATEVLGTTKIQYGEHLVDLTPEWRRLHMVDAIKEYVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKEREQGNDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRH 3e9h D 2.1 BS02 KAA D 1 G207 E231 R253 H261 N262 F265 M267 E269 Y271 E411 H412 N414 F416 E418 G467 R470 G199 E223 R245 H253 N254 F257 M259 E261 Y263 E403 H404 N406 F408 E410 G459 R462 R253 E255 R260 H261 E411 N414 R470 R245 E247 R252 H253 E403 N406 R462 6.1.1.6 0000049,0000166,0000287,0003676,0004812,0004824,0005524,0005737,0005829,0006412,0006418,0006430,0016740,0046872 Q9RHV9 19174549 2005 ELNDQLRVRREKLKKIEELGVDPFGKRFERTHKAEELFELYGDLSKEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQDDVGEQQYELFKISDLGDIVGVRGTMFKTKVGELSIKVSSYEFLTKALRPLPEKDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMMHAVAGGAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGISTRHNPEFTMLELYEAYADFRDIMKLTENLIAHIATEVLGTTKIQYGEHLVDLTPEWRRLHMVDAIKEYVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKEREQGNDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRH 4eqe B 1.52 BS01 KAA B 1 I18 D43 I44 N99 G105 S107 H112 H114 I7 D32 I33 N88 G94 S96 H101 H103 3.4.22.-,3.9.1.- 0000118,0000166,0003824,0005080,0005515,0005634,0005654,0005737,0005829,0005856,0005886,0006355,0006508,0006915,0007165,0008234,0009154,0016787,0016926,0016929,0043530,0050850,0070062,0072332 P49773 22329685 202 RPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 6c86 A 2.15 BS01 KAA A 1 G249 A271 E273 R295 T302 H303 N304 F307 E311 Y313 E464 L465 N467 Y469 E471 G516 W517 G518 G520 R523 G205 A227 E229 R251 T258 H259 N260 F263 E267 Y269 E420 L421 N423 Y425 E427 G472 W473 G474 G476 R479 R295 E297 T302 H303 E464 N467 R523 R251 E253 T258 H259 E420 N423 R479 6.1.1.6 0000049,0000166,0003676,0004812,0004824,0005524,0005737,0005829,0006418,0006430,0016020 Q5CR27 601 SHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAISGLKDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMRN 6c86 B 2.15 BS01 KAA B 1 G249 A271 E273 R295 T302 H303 N304 F307 E311 Y313 E464 L465 N467 Y469 E471 G516 W517 G518 G520 R523 G201 A223 E225 R247 T254 H255 N256 F259 E263 Y265 E416 L417 N419 Y421 E423 G468 W469 G470 G472 R475 R295 E297 T302 H303 E464 N467 R523 R247 E249 T254 H255 E416 N419 R475 6.1.1.6 0000049,0000166,0003676,0004812,0004824,0005524,0005737,0005829,0006418,0006430,0016020 Q5CR27 601 SHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAIDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMRN 6chd A 2.5 BS01 KAA A 1 G277 A299 E301 R323 H331 N332 F335 E339 Y341 E494 I495 N497 Y499 E501 G546 G548 G550 R553 G207 A229 E231 R253 H261 N262 F265 E269 Y271 E424 I425 N427 Y429 E431 G476 G478 G480 R483 2.7.7.-,6.1.1.6 0000049,0000166,0002276,0002863,0003676,0003877,0004812,0004824,0005515,0005524,0005576,0005615,0005634,0005654,0005737,0005739,0005759,0005829,0005886,0006412,0006418,0006430,0008033,0010165,0015966,0016597,0016740,0017101,0042802,0042803,0043032,0045893,0070371 Q15046 601 VDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPE 6chd B 2.5 BS01 KAA B 1 G277 A299 E301 R323 H331 N332 F335 E339 Y341 E494 N497 Y499 E501 G546 W547 G548 G550 R553 G203 A225 E227 R249 H257 N258 F261 E265 Y267 E420 N423 Y425 E427 G472 W473 G474 G476 R479 2.7.7.-,6.1.1.6 0000049,0000166,0002276,0002863,0003676,0003877,0004812,0004824,0005515,0005524,0005576,0005615,0005634,0005654,0005737,0005739,0005759,0005829,0005886,0006412,0006418,0006430,0008033,0010165,0015966,0016597,0016740,0017101,0042802,0042803,0043032,0045893,0070371 Q15046 601 SVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPE 6ilh A 2.501 BS01 KAA A 1 E301 R323 H331 N332 F335 E339 Y341 E494 N497 Y499 E501 G550 R553 E228 R250 H258 N259 F262 E266 Y268 E421 N424 Y426 E428 G477 R480 2.7.7.-,6.1.1.6 0000166,0003676,0004812,0004824,0005524,0005737,0006418,0006430 Q15046 30733335 601 VDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDHMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKP 6ilh B 2.501 BS01 KAA B 1 E301 R323 H331 N332 F335 E339 Y341 E494 N497 Y499 E501 G546 G548 G550 R553 E230 R252 H260 N261 F264 E268 Y270 E423 N426 Y428 E430 G475 G477 G479 R482 2.7.7.-,6.1.1.6 0000166,0003676,0004812,0004824,0005524,0005737,0006418,0006430 Q15046 30733335 601 DPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDHMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKP 7ea9 A 2.5 BS01 KAA A 1 E301 R323 T330 H331 N332 F335 E339 Y341 E494 I495 N497 Y499 E501 G546 G548 G550 R553 E228 R250 T257 H258 N259 F262 E266 Y268 E421 I422 N424 Y426 E428 G473 G475 G477 R480 2.7.7.-,6.1.1.6 0000166,0003676,0004812,0004824,0005524,0005737,0006418,0006430 Q15046 33784510 601 VDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFHDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKP 7ea9 B 2.5 BS01 KAA B 1 E301 R323 H331 N332 F335 E339 Y341 E494 I495 N497 Y499 E501 G546 G548 G550 R553 E226 R248 H256 N257 F260 E264 Y266 E419 I420 N422 Y424 E426 G471 G473 G475 R478 2.7.7.-,6.1.1.6 0000166,0003676,0004812,0004824,0005524,0005737,0006418,0006430 Q15046 33784510 601 DPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFHDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKP 7ea9 C 2.5 BS01 KAA C 1 E301 R323 T330 H331 N332 F335 E339 Y341 E494 I495 N497 Y499 E501 G546 G550 R553 E228 R250 T257 H258 N259 F262 E266 Y268 E421 I422 N424 Y426 E428 G473 G477 R480 2.7.7.-,6.1.1.6 0000166,0003676,0004812,0004824,0005524,0005737,0006418,0006430 Q15046 33784510 601 VDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFHDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKP 7ea9 D 2.5 BS01 KAA D 1 E301 R323 H331 N332 F335 E339 Y341 E494 I495 N497 Y499 E501 G546 G548 G550 R553 E226 R248 H256 N257 F260 E264 Y266 E419 I420 N422 Y424 E426 G471 G473 G475 R478 2.7.7.-,6.1.1.6 0000166,0003676,0004812,0004824,0005524,0005737,0006418,0006430 Q15046 33784510 601 DPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFHDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKP 7f6w A 2.607 BS01 KAA A 1 E304 R326 H334 N335 F338 E342 E497 I498 N500 Y502 E504 G549 G553 R556 E232 R254 H262 N263 F266 E270 E425 I426 N428 Y430 E432 G477 G481 R484 6.1.1.6 0000166,0003676,0004812,0004824,0005524,0005737,0006418,0006430 P15180 35133502 601 DPSQYFETRSRQIQELRKTHEPNPYPHKFHVSISNPEFLAKYAHLKKGETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQDYCDPDSYEKDHDLLKRGDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPAFKDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRRFLDQRKFIEVETPMMNVIAGGATAKPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMTHNPEFTTCEFYQAYADVYDLMDMTELMFSEMVKEITGSYIIKYHPDPADPAKELELNFSRPWKRINMIEELEKVFNVKFPSGDQLHTAETGEFLKKILVDNKLECPPPLTNARMLDKLVGELEDTCINPTFIFGHPQMMSPLAKYSRDQPGLCERFEVFVATKEICNAYTELNDPFDQRARFEEQARQKDQGDDEAQLVDETFCNALEYGLPPTGGWGCGIDRLAMFLTDSNTIREVLLFPTLKP