5ar5 A 2.66 BS01 IQ7 A 1 L24 V32 A45 K47 L79 T95 Y97 M98 G101 L153 D164 L21 V29 A42 K44 L72 T88 Y90 M91 G94 L146 D157 D146 K148 Q150 N151 D164 T189 D139 K141 Q143 N144 D157 T169 2.7.10.2,2.7.11.1 0004672,0005524,0006468 -logKd/Ki=6.30, IC50=500nM IC50=12nM O43353 26455654 1312 EAICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLHLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMEGGTIIYMPPENYEPSIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLK 5ar5 B 2.66 BS01 IQ7 B 1 L24 V32 A45 K47 L79 Y97 M98 D164 L21 V29 A42 K44 L72 Y90 M91 D157 D146 K148 Q150 N151 D164 T189 D139 K141 Q143 N144 D157 T165 2.7.10.2,2.7.11.1 0004672,0005524,0006468 IC50=12nM O43353 26455654 1311 EAICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLHLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRTIIYMPPENYESIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLK