1lr8 A 2.1 BS01 IHS A 1 N80 K81 R86 N17 K18 R23 ? Kd=10nM P21674 12867435 30 ETCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGKCK 1u25 A 2.5 BS01 IHS A 1 K71 H74 K286 K47 H50 K262 3.1.3.72 0016311,0016787 Q7WUJ1 15530366 2165 TEPVGSYARAERPQDFEGFVWRLDNDGKEALPRNFRTSADALRAPEKKFHLDAAYVPSREGMDALHISGSSAFTPAQLKNVAAKLREKTAGPIYDVDLRQESHGYLDGIPVSWYGERDWANLGKSQHEALADERHRLHAALHKTVYIAPLGKHKLPEGGEVRRVQKVQTEQEVAEAAGMRYFRIAATDHVWPTPENIDRFLAFYRTLPQDAWLHFHCEAGVGRTTAFMVMTDMLKNPSVSLKDILYRQHEIGGFYYGEFPIKTKDKDSWKTKYYREKIVMIEQFYRYVQENRADGYQTPWSVWLKSHPAKA 1u25 A 2.5 BS02 IHS A 2 Q150 H151 L154 Y205 R207 R223 Q126 H127 L130 Y181 R183 R199 3.1.3.72 0016311,0016787 Q7WUJ1 15530366 2167 TEPVGSYARAERPQDFEGFVWRLDNDGKEALPRNFRTSADALRAPEKKFHLDAAYVPSREGMDALHISGSSAFTPAQLKNVAAKLREKTAGPIYDVDLRQESHGYLDGIPVSWYGERDWANLGKSQHEALADERHRLHAALHKTVYIAPLGKHKLPEGGEVRRVQKVQTEQEVAEAAGMRYFRIAATDHVWPTPENIDRFLAFYRTLPQDAWLHFHCEAGVGRTTAFMVMTDMLKNPSVSLKDILYRQHEIGGFYYGEFPIKTKDKDSWKTKYYREKIVMIEQFYRYVQENRADGYQTPWSVWLKSHPAKA 1u25 A 2.5 BS03 IHS C 1 K72 K176 K288 K48 K152 K264 3.1.3.72 0016311,0016787 Q7WUJ1 15530366 2166 TEPVGSYARAERPQDFEGFVWRLDNDGKEALPRNFRTSADALRAPEKKFHLDAAYVPSREGMDALHISGSSAFTPAQLKNVAAKLREKTAGPIYDVDLRQESHGYLDGIPVSWYGERDWANLGKSQHEALADERHRLHAALHKTVYIAPLGKHKLPEGGEVRRVQKVQTEQEVAEAAGMRYFRIAATDHVWPTPENIDRFLAFYRTLPQDAWLHFHCEAGVGRTTAFMVMTDMLKNPSVSLKDILYRQHEIGGFYYGEFPIKTKDKDSWKTKYYREKIVMIEQFYRYVQENRADGYQTPWSVWLKSHPAKA 1u25 C 2.5 BS01 IHS A 1 K72 V245 K288 K47 V220 K263 3.1.3.72 0016311,0016787 Q7WUJ1 15530366 2165 EPVGSYARAERPQDFEGFVWRLDNDGKEALPRNFRTSADALRAPEKKFHLDAAYVPSREGMDALHISGSSAFTPAQLKNVAAKLREKTAGPIYDVDLRQESHGYLDGIPVSWYGERDWANLGKSQHEALADERHRLHAALHKTVYIAPLGKHKLPEGGEVRRVQKVQTEQEVAEAAGMRYFRIAATDHVWPTPENIDRFLAFYRTLPQDAWLHFHCEAGVGRTTAFMVMTDMLKNPSVSLKDILYRQHEIGGFYYGEFPIKTKDKDSWKTKYYREKIVMIEQFYRYVQENRADGYQTPWSVWLKSHPAKA 1u25 C 2.5 BS02 IHS C 1 K71 H74 P284 K286 K46 H49 P259 K261 3.1.3.72 0016311,0016787 Q7WUJ1 15530366 2166 EPVGSYARAERPQDFEGFVWRLDNDGKEALPRNFRTSADALRAPEKKFHLDAAYVPSREGMDALHISGSSAFTPAQLKNVAAKLREKTAGPIYDVDLRQESHGYLDGIPVSWYGERDWANLGKSQHEALADERHRLHAALHKTVYIAPLGKHKLPEGGEVRRVQKVQTEQEVAEAAGMRYFRIAATDHVWPTPENIDRFLAFYRTLPQDAWLHFHCEAGVGRTTAFMVMTDMLKNPSVSLKDILYRQHEIGGFYYGEFPIKTKDKDSWKTKYYREKIVMIEQFYRYVQENRADGYQTPWSVWLKSHPAKA 1u26 A 2.5 BS01 IHS A 1 R46 R141 D142 K178 D212 H213 C241 E242 A243 G244 V245 G246 R247 K294 Y298 R24 R119 D120 K156 D190 H191 C219 E220 A221 G222 V223 G224 R225 K272 Y276 3.1.3.72 0016311,0016787 Q7WUJ1 15530366 2166 TVTEPVGSYARAERPQDFEGFVWRLDNDGKEALPRNFRTSADALRAPEKKFHLDAAYVPSREGMDALHISGSSAFTPAQLKNVAAKLREKTAGPIYDVDLRQESHGYLDGIPVSWYGERDWANLGKSQHEALADERHRLHAALHKTVYIAPLGKHKLPEGGEVRRVQKVQTEQEVAEAAGMRYFRIAATDHVWPTPENIDRFLAFYRTLPQDAWLHFHCEAGVGRTTAFMVMTDMLKNPSVSLKDILYRQHEIGGFYYGEFPIKTKDKDSWKTKYYREKIVMIEQFYRYVQENRADGYQTPWSVWLKSHPAKAL 1u26 A 2.5 BS02 IHS A 2 S149 Q150 H151 L154 R223 S127 Q128 H129 L132 R201 3.1.3.72 0016311,0016787 Q7WUJ1 15530366 2167 TVTEPVGSYARAERPQDFEGFVWRLDNDGKEALPRNFRTSADALRAPEKKFHLDAAYVPSREGMDALHISGSSAFTPAQLKNVAAKLREKTAGPIYDVDLRQESHGYLDGIPVSWYGERDWANLGKSQHEALADERHRLHAALHKTVYIAPLGKHKLPEGGEVRRVQKVQTEQEVAEAAGMRYFRIAATDHVWPTPENIDRFLAFYRTLPQDAWLHFHCEAGVGRTTAFMVMTDMLKNPSVSLKDILYRQHEIGGFYYGEFPIKTKDKDSWKTKYYREKIVMIEQFYRYVQENRADGYQTPWSVWLKSHPAKAL 1u26 B 2.5 BS01 IHS A 2 Q150 H151 R223 Q127 H128 R200 3.1.3.72 0016311,0016787 Q7WUJ1 15530366 2167 VTEPVGSYARAERPQDFEGFVWRLDNDGKEALPRNFRTSADALRAPEKKFHLDAAYVPSREGMDALHISGSSAFTPAQLKNVAAKLREKTAGPIYDVDLRQESHGYLDGIPVSWYGERDWANLGKSQHEALADERHRLHAALHKTVYIAPLGKHKLPEGGEVRRVQKVQTEQEVAEAAGMRYFRIAATDHVWPTPENIDRFLAFYRTLPQDAWLHFHCEAGVGRTTAFMVMTDMLKNPSVSLKDILYRQHEIGGFYYGEFPIKTKDKDSWKTKYYREKIVMIEQFYRYVQENRADGYQTPWSVWLKSHPAKAL 1u26 B 2.5 BS02 IHS B 1 R46 D142 D212 H213 E242 A243 V245 G246 K294 Y298 R23 D119 D189 H190 E219 A220 V222 G223 K271 Y275 3.1.3.72 0016311,0016787 Q7WUJ1 15530366 2165 VTEPVGSYARAERPQDFEGFVWRLDNDGKEALPRNFRTSADALRAPEKKFHLDAAYVPSREGMDALHISGSSAFTPAQLKNVAAKLREKTAGPIYDVDLRQESHGYLDGIPVSWYGERDWANLGKSQHEALADERHRLHAALHKTVYIAPLGKHKLPEGGEVRRVQKVQTEQEVAEAAGMRYFRIAATDHVWPTPENIDRFLAFYRTLPQDAWLHFHCEAGVGRTTAFMVMTDMLKNPSVSLKDILYRQHEIGGFYYGEFPIKTKDKDSWKTKYYREKIVMIEQFYRYVQENRADGYQTPWSVWLKSHPAKAL 3amr A 1.25 BS01 IHS A 1 D24 K48 K49 R94 Y131 Q251 D286 D23 K47 K48 R93 Y130 Q250 D285 3.1.3.8 0005576,0016158,0016787 O31097 21463636 900 LSDPYHFTVNAAAETEPVDTAGDAADDPAIWLDPKTPQNSKLITTNKKSGLVVYSLDGKMLHSYNTGKLNNVDIRYDFPLNGKKVDIAAASNRSEGKNTIEIYAIDGKNGTLQSMTDPDHPIATAINEVYGFTLYHSQKTGKYYAMVTGKEGEFEQYELKADKNGYISGKKVRAFKMNSQTEGMAADDEYGRLYIAEEDEAIWKFSAEPDGGSNGTVIDRADGRHLTRDIEGLTIYYAADGKGYLMASSQGNSSYAIYDRQGKNKYVADFRITDGPETDGTSDTDGIDVLGFGLGPEYPFGIFVAQDGENIDHGQKANQNFKIVPWERIADQIGFRPLANEQVDPRKLTDRS 3ams A 2.08 BS01 IHS A 1 D24 K48 K49 R94 Y131 Q251 D286 D23 K47 K48 R93 Y130 Q250 D285 3.1.3.8 0005576,0016158,0016787 O31097 21463636 4000 LSDPYHFTVNAAAETEPVDTAGDAADDPAIWLDPKTPQNSKLITTNKKSGLVVYSLDGKMLHSYNTGKLNNVDIRYDFPLNGKKVDIAAASNRSEGKNTIEIYAIDGKNGTLQSMTDPDHPIATAINEVYGFTLYHSQKTGKYYAMVTGKEGEFEQYELKADKNGYISGKKVRAFKMNSQTEGMAADDEYGRLYIAEEDEAIWKFSAEPDGGSNGTVIDRADGRHLTRDIEGLTIYYAADGKGYLMASSQGNSSYAIYDRQGKNKYVADFRITDGPETDGTSDTDGIDVLGFGLGPEYPFGIFVAQDGENIDHGQKANQNFKIVPWERIADQIGFRPLANEQVDPRKLTDRS 3k4q A 2.2 BS01 IHS A 1 Q27 Y28 R58 H59 R62 K68 R142 K278 H338 D339 Q21 Y22 R52 H53 R56 K62 R136 K272 H332 D333 3.1.3.-,3.1.3.8 0003993,0005576,0016158,0016787,0016791 Ki=4.6uM -logKd/Ki=5.34, Ki=4.6uM P34752 20541524 500 SCDTVDQGYQCFSETSHLWGQYAPFFSLANESVISPEVPAGCRVTFAQVLSRHGARYPTDSKGKKYSALIEEIQQNATTFDGKYAFLKTYNYSLGADDLTPFGEQELVNSGIKFYQRYESLTRNIVPFIRSSGSSRVIASGKKFIEGFQSTKLKDPRAQPGQSSPKIDVVISEASSSNNTLDPGTCTVFEDSELADTVEANFTATFVPSIRQRLENDLSGVTLTDTEVTYLMDMCSFDTISTSTVDTKLSPFCDLFTHDEWINYDYLQSLKKYYGHGAGNPLGPTQGVGYANELIARLTHSPVHDDTSSNHTLDSSPATFPLNSTLYADFSHDNGIISILFALGLYNGTKPLSTTTVENITQTDGFSSAWTVPFASRLYVEMMQCQAEQEPLVRVLVNDRVVPLHGCPVDALGRCTRDSFVRGLSFARSGGDWAECFA 3k4q B 2.2 BS01 IHS B 1 Q27 Y28 R58 H59 R62 T65 K68 R142 K278 H338 D339 Q21 Y22 R52 H53 R56 T59 K62 R136 K272 H332 D333 3.1.3.-,3.1.3.8 0003993,0005576,0016158,0016787,0016791 Ki=4.6uM P34752 20541524 500 SCDTVDQGYQCFSETSHLWGQYAPFFSLANESVISPEVPAGCRVTFAQVLSRHGARYPTDSKGKKYSALIEEIQQNATTFDGKYAFLKTYNYSLGADDLTPFGEQELVNSGIKFYQRYESLTRNIVPFIRSSGSSRVIASGKKFIEGFQSTKLKDPRAQPGQSSPKIDVVISEASSSNNTLDPGTCTVFEDSELADTVEANFTATFVPSIRQRLENDLSGVTLTDTEVTYLMDMCSFDTISTSTVDTKLSPFCDLFTHDEWINYDYLQSLKKYYGHGAGNPLGPTQGVGYANELIARLTHSPVHDDTSSNHTLDSSPATFPLNSTLYADFSHDNGIISILFALGLYNGTKPLSTTTVENITQTDGFSSAWTVPFASRLYVEMMQCQAEQEPLVRVLVNDRVVPLHGCPVDALGRCTRDSFVRGLSFARSGGDWAECFA 4aro A 1.59 BS01 IHS A 1 R18 H19 R22 T25 K26 R94 H128 T219 F257 H306 D307 R15 H16 R19 T22 K23 R89 H123 T207 F245 H294 D295 3.1.3.26 0016311,0030288,0050308 -logKd/Ki=6.80, Kd~160nM H9TUK5 23741456 501 APAGFQLEKVVILSRHGVRAPTKMTQTMRDVTPHQWPEWPVKLGYITPRGEHLISLMGGFYRERFQQQGLLPKCPTPDAVYVWADVDQRTRKTGEAFLAGLAPQCDLAIHHQQNTQQADPLFHPVKAGICSMDKSQVHAAVEKQAGTPIETLNQRYQASLALMSSVLDFPKSPYCQQHLCDFSQAMPSRLAIGNKVALEGAVGLASTLAEIFLLEHAQGMPKVAWGNIHTEQQWNSLLKLHNAQFDLMSRTPYIAKHNGTPLLQTIAHALGSNITSRPLPDISPDNKILFIAGHDANIANISGMLGMTWTLPGQPDNTPPGGALVFERWVDNAGKPYVSVNMVYQTLAQLHDQAPLTLQHPAGSVRLNIPGCSDQTPDGYCPLSTFSRLVSHSVEPACQLP 4aro A 1.59 BS02 IHS A 2 P43 P51 R52 Q230 M232 P40 P48 R49 Q218 M220 3.1.3.26 0016311,0030288,0050308 -logKd/Ki=6.80, Kd~160nM H9TUK5 23741456 502 APAGFQLEKVVILSRHGVRAPTKMTQTMRDVTPHQWPEWPVKLGYITPRGEHLISLMGGFYRERFQQQGLLPKCPTPDAVYVWADVDQRTRKTGEAFLAGLAPQCDLAIHHQQNTQQADPLFHPVKAGICSMDKSQVHAAVEKQAGTPIETLNQRYQASLALMSSVLDFPKSPYCQQHLCDFSQAMPSRLAIGNKVALEGAVGLASTLAEIFLLEHAQGMPKVAWGNIHTEQQWNSLLKLHNAQFDLMSRTPYIAKHNGTPLLQTIAHALGSNITSRPLPDISPDNKILFIAGHDANIANISGMLGMTWTLPGQPDNTPPGGALVFERWVDNAGKPYVSVNMVYQTLAQLHDQAPLTLQHPAGSVRLNIPGCSDQTPDGYCPLSTFSRLVSHSVEPACQLP 4fdu A 2.293 BS01 IHS A 1 R58 H59 R62 T65 R149 R183 H323 A324 E325 R31 H32 R35 T38 R122 R156 H296 A297 E298 ? 0016787 Q89YI8 24529702 501 HMQTKIQKYAGTAMPYPNRTMTPFYINHLGRHGARFPTSRKALDKVEKVLVSAQQENGLTSEGMALLSMIRRLSRLFDGQWGKLSKLGETEQEGIAGRMIRNYPQLFSNSAKIEAIATYVPRSINSMDAFLSCMIRHNPALQVQRSEGKQYNHILRFFDLNKSYVNYKEKGDWLPIYKAFVHKKISPVPIMKKFLLNPEQYLDKEAEEFVMALFSVAAILPDTSIPLNLEDLFTLDEWHRYWQTQNLRQYMSKSSAPVGKMLPVAIAWPLLSEFIRSAQEVISGKSDYQANFRFAHAETVIPFVSLMGIEKTDVQVCRPDSVSVYWKDYEISPMAANVQWLFYRDRDQRIWVKILLNEEAAALPISTACFPYYSWEKTRIFFNQRIEMAKKTLSVFN 4fdu B 2.293 BS01 IHS B 1 T30 R58 H59 R62 T65 R149 R183 F185 K280 H323 A324 E325 T10 R29 H30 R33 T36 R120 R154 F156 K251 H294 A295 E296 ? 0016787 Q89YI8 24529702 501 QTKIQKYAGTAMPYPNRTMTPFYINHLGRHGARFPTSRKALDKVEKVLVSAQQENGLTSEGMALLSMIRRLSRLFDGQWGKLSKLGETEQEGIAGRMIRNYPQLFSNSAKIEAIATYVPRSINSMDAFLSCMIRHNPALQVQRSEGKQYNHILRFFDLNKSYVNYKEKGDWLPIYKAFVHKKISPVPIMKKFLLNPEQYLDKEAEEFVMALFSVAAILPDTSIPLNLEDLFTLDEWHRYWQTQNLRQYMSKSSAPVGKMLPVAIAWPLLSEFIRSAQEVISGKSDYQANFRFAHAETVIPFVSLMGIEKTDVQVCRPDSVSVYWKDYEISPMAANVQWLFYRDRDQRIWVKILLNEEAAALPISTACFPYYSWEKTRIFFNQRIEMAKKTLSVFN 4tsr A 2.07 BS01 IHS A 1 R16 H17 R20 T23 K24 R92 M216 F254 H303 D304 R11 H12 R15 T18 K19 R87 M205 F243 H292 D293 3.1.3.-,3.6.1.- 0003924,0003993,0008252,0008707,0016036,0016787,0030288,0042597,0050308,0052745,0071454 P07102 505 LKLESVVIVSRHGVRAPTKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQSGQVAIIADTDERTRKTGEAFAAGLAPDCAITVHTQVDTSSPDPLFNPLKTGVCQLDNANVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLKRCSLTQALPSELKVSADNVALTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQFYLLQRTPEVARSRATPLLDLIKTALTPHPPQKQAYGVTLPTSVLFIAGHDTNLANLGGALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNTPPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL 6gj2 A 1.68 BS04 IHS A 1 N206 Y218 S219 H229 N258 H259 H350 N202 Y214 S215 H225 N254 H255 H346 D174 D201 Y204 N258 H259 H340 A349 H350 H377 H379 D170 D197 Y200 N254 H255 H336 A345 H346 H373 H375 3.1.3.2 0003993,0016787,0046872 F6MIW5 35529950 625 EPASTLEGPSRPVTVPLRHAVDLPDTDPRVQRRVTGWAPEQIAVALSAAPTSAWVSWITGDFQMGGAVKPLDPGTVGSVVRYGLAADSLVREATGDALVYSQLYPFEGLQNYTSGIIHHVRLQGLEPGTKYYYQCGDPSIPGAMSAVHAFRTMPAVGPRSYPGRIAVVGDLGLTYNTTSTVEHMASNQPDLVLLLGDVSYANLYLTNGTGTDCYSCSFAKSTPIHETYQPRWDYWGRYMEPVTSSTPMMVVEGNHEIEQQIGNKTFAAYSARFAFPSMESESFSPFYYSFDAGGIHFIMLAAYADYSKSGEQYRWLEKDLAKVDRSVTPWLVAGWHAPWYSTYKAHYREAECMRVAMEELLYSYGLDIVFTGHVHAYERSNRVFNYTLDPCGAVHISVGDGGNREKMATTHADDPGRCPEPMSTPDAFMGGFCAFNFTSGPAAGSFCWDRQPDYSAYRESSFGHGILEVKNETHALWKWHRNQDLYQGAVGDEIYIVREPERCL 6rxe A 1.84 BS01 IHS A 1 K13 R44 H45 R48 S51 K54 Y55 R142 Y189 K192 H399 A400 E401 K7 R38 H39 R42 S45 K48 Y49 R136 Y183 K186 H393 A394 E395 ? B7GTV0 33454010 601 GRYYSSKQPYVAPNDATASSYSKAPKGYGPIYTESMARHGSRGLSSYKYDALLMRMAETAARDGGFKSEAIKAEFVKNLSGITAANVENGYGMLTGQGAQQHYGIGERAYQRNRSLFDQAAADGGTIAYQSSGEARATESGENFEKGFNEASGGRLIGNVSAPTNPADSGNGKDFQKNPDTLYFHKVQNPDGTSKVPGTKAYDIANNYQNFVANDATIAGAEKTIGDNVDVKRASHDLLSQIFTEEFLAKLENGEYKWYNTTDGTKKGGKNCAPGADASKDPDACGEVSKKIKSEYDAAMDLYNLYIIAADMHNENTGDHTFAFDQYFQGAYADDARMFAWALDAEDFYEKGPSYAGQNETYSIAQPLLDDFLNTIDARVNGGSTVATFRFAHAETMMPFAALLGLPGSTQQAPASTTDVYTYGNNEWRGESVTPMAANVQWDVYARYTPIVRMLYNENEVPFRSECTPVADGSTWYKLTELKSCLAADHKTLGQDARI 6rxe B 1.84 BS01 IHS B 1 K13 R44 H45 R48 S51 K54 Y55 R142 Y189 H191 K192 H399 A400 E401 K7 R38 H39 R42 S45 K48 Y49 R136 Y183 H185 K186 H393 A394 E395 ? B7GTV0 33454010 601 GRYYSSKQPYVAPNDATASSYSKAPKGYGPIYTESMARHGSRGLSSYKYDALLMRMAETAARDGGFKSEAIKAEFVKNLSGITAANVENGYGMLTGQGAQQHYGIGERAYQRNRSLFDQAAADGGTIAYQSSGEARATESGENFEKGFNEASGGRLIGNVSAPTNPADSGNGKDFQKNPDTLYFHKVQNPDGTSKVPGTKAYDIANNYQNFVANDATIAGAEKTIGDNVDVKRASHDLLSQIFTEEFLAKLENGEYKWYNTTDGTKKGGKNCAPGADASKDPDACGEVSKKIKSEYDAAMDLYNLYIIAADMHNENTGDHTFAFDQYFQGAYADDARMFAWALDAEDFYEKGPSYAGQNETYSIAQPLLDDFLNTIDARVNGGSTVATFRFAHAETMMPFAALLGLPGSTQQAPASTTDVYTYGNNEWRGESVTPMAANVQWDVYARKGEDGQRYTPIVRMLYNENEVPFRSECTPVADGSTWYKLTELKSCLAADHKTLGQDARI 7r5y A 1.97 BS01 IHS A 1 K37 R66 H67 R70 K77 K155 R157 K191 H329 D330 T331 K17 R46 H47 R50 K57 K135 R137 K171 H309 D310 T311 ? 0016787 R7PD89 501 QTARDEIIQDPALAAGKYYAYEAPVSDKVSKAPAGYEPFYISAFARHGSRYLTDEEKYAEPVSVLRKADREGYLTTDGKKALQVMERLWKEAENRYGELTAKGAAQHQGLVERMYKHYPQVFVKGAHVDARSTYKTRAFLSMAAACVRLAQLNSGLLITQDASAHDAYYIKYKNKTFEQQHLAQSDSVYRIADSVYVHPARLMKQLFTRNVSAEELGVSPVVLMGELFELDGISQSSYGQEGLSFLFTDDERYDMWQRNNFEWYYEKGASPLSDCCMYHLERNLLENFIMTADTAIASPYRCVTLRYGHDTNLAPLAALMGMNRLQTETTDWQQIADTYRTYRIIPMCGNIQLIFYRRKGSSDILVKPLLNEREVTLPVETDCAPFYHWADVRAYWQKVADSIVLPDSG 7r5y B 1.97 BS01 IHS B 1 K37 R66 H67 R70 K77 K155 R157 K191 H329 D330 T331 K17 R46 H47 R50 K57 K135 R137 K171 H309 D310 T311 ? 0016787 R7PD89 501 QTARDEIIQDPALAAGKYYAYEAPVSDKVSKAPAGYEPFYISAFARHGSRYLTDEEKYAEPVSVLRKADREGYLTTDGKKALQVMERLWKEAENRYGELTAKGAAQHQGLVERMYKHYPQVFVKGAHVDARSTYKTRAFLSMAAACVRLAQLNSGLLITQDASAHDAYYIKYKNKTFEQQHLAQSDSVYRIADSVYVHPARLMKQLFTRNVSAEELGVSPVVLMGELFELDGISQSSYGQEGLSFLFTDDERYDMWQRNNFEWYYEKGASPLSDCCMYHLERNLLENFIMTADTAIASPYRCVTLRYGHDTNLAPLAALMGMNRLQTETTDWQQIADTYRTYRIIPMCGNIQLIFYRRKGSSDILVKPLLNEREVTLPVETDCAPFYHWADVRAYWQKVADSIVLPD 7r5y C 1.97 BS01 IHS C 1 K37 Y38 R66 H67 R70 T73 K77 K155 R157 K191 H329 D330 T331 K17 Y18 R46 H47 R50 T53 K57 K135 R137 K171 H309 D310 T311 ? 0016787 R7PD89 501 QTARDEIIQDPALAAGKYYAYEAPVSDKVSKAPAGYEPFYISAFARHGSRYLTDEEKYAEPVSVLRKADREGYLTTDGKKALQVMERLWKEAENRYGELTAKGAAQHQGLVERMYKHYPQVFVKGAHVDARSTYKTRAFLSMAAACVRLAQLNSGLLITQDASAHDAYYIKYKNKTFEQQHLAQSDSVYRIADSVYVHPARLMKQLFTRNVSAEELGVSPVVLMGELFELDGISQSSYGQEGLSFLFTDDERYDMWQRNNFEWYYEKGASPLSDCCMYHLERNLLENFIMTADTAIASPYRCVTLRYGHDTNLAPLAALMGMNRLQTETTDWQQIADTYRTYRIIPMCGNIQLIFYRRKGSSDILVKPLLNEREVTLPVETDCAPFYHWADVRAYWQKVADSIVLPDS 7r5y D 1.97 BS01 IHS D 1 K37 R66 H67 R70 K77 K155 R157 K191 W283 H329 D330 T331 K17 R46 H47 R50 K57 K135 R137 K171 W263 H309 D310 T311 ? 0016787 R7PD89 501 QTARDEIIQDPALAAGKYYAYEAPVSDKVSKAPAGYEPFYISAFARHGSRYLTDEEKYAEPVSVLRKADREGYLTTDGKKALQVMERLWKEAENRYGELTAKGAAQHQGLVERMYKHYPQVFVKGAHVDARSTYKTRAFLSMAAACVRLAQLNSGLLITQDASAHDAYYIKYKNKTFEQQHLAQSDSVYRIADSVYVHPARLMKQLFTRNVSAEELGVSPVVLMGELFELDGISQSSYGQEGLSFLFTDDERYDMWQRNNFEWYYEKGASPLSDCCMYHLERNLLENFIMTADTAIASPYRCVTLRYGHDTNLAPLAALMGMNRLQTETTDWQQIADTYRTYRIIPMCGNIQLIFYRRKGSSDILVKPLLNEREVTLPVETDCAPFYHWADVRAYWQKVADSIVLPDSGMQHD 7r5y E 1.97 BS01 IHS E 1 K37 R66 H67 R70 K77 K155 R157 K191 W283 H329 D330 T331 K18 R47 H48 R51 K58 K136 R138 K172 W264 H310 D311 T312 ? 0016787 R7PD89 501 MQTARDEIIQDPALAAGKYYAYEAPVSDKVSKAPAGYEPFYISAFARHGSRYLTDEEKYAEPVSVLRKADREGYLTTDGKKALQVMERLWKEAENRYGELTAKGAAQHQGLVERMYKHYPQVFVKGAHVDARSTYKTRAFLSMAAACVRLAQLNSGLLITQDASAHDAYYIKYKNKTFEQQHLAQSDSVYRIADSVYVHPARLMKQLFTRNVSAEELGVSPVVLMGELFELDGISQSSYGQEGLSFLFTDDERYDMWQRNNFEWYYEKGASPLSDCCMYHLERNLLENFIMTADTAIASPYRCVTLRYGHDTNLAPLAALMGMNRLQTETTDWQQIADTYRTYRIIPMCGNIQLIFYRRKGSSDILVKPLLNEREVTLPVETDCAPFYHWADVRAYWQKVADSIVLPDSGMQHD 7r5y F 1.97 BS01 IHS F 1 K37 R66 H67 R70 K155 R157 K191 H329 D330 T331 K18 R47 H48 R51 K136 R138 K172 H310 D311 T312 ? 0016787 R7PD89 501 MQTARDEIIQDPALAAGKYYAYEAPVSDKVSKAPAGYEPFYISAFARHGSRYLTDEEKYAEPVSVLRKADREGYLTTDGKKALQVMERLWKEAENRYGELTAKGAAQHQGLVERMYKHYPQVFVKGAHVDARSTYKTRAFLSMAAACVRLAQLNSGLLITQDASAHDAYYIKYKNKTFEQQHLAQSDSVYRIADSVYVHPARLMKQLFTRNVSAEELGVSPVVLMGELFELDGISQSSYGQEGLSFLFTDDERYDMWQRNNFEWYYEKGASPLSDCCMYHLERNLLENFIMTADTAIASPYRCVTLRYGHDTNLAPLAALMGMNRLQTETTDWQQIADTYRTYRIIPMCGNIQLIFYRRKGSSDILVKPLLNEREVTLPVETDCAPFYHWADVRAYWQKVADSIVLPDSGMQHD 7z2s A 1.72 BS01 IHS A 1 R16 H17 R20 T23 K24 R92 M216 F254 H303 D304 R18 H19 R22 T25 K26 R94 M211 F249 H298 D299 3.1.3.-,3.6.1.- 0003924,0003993,0008252,0008707,0016036,0016787,0030288,0042597,0050308,0052745,0071454 P07102 35683026 501 GPQSEPELKLESVVIVSRHGVRAPTKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQSGQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNANVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLKCSLTQALPSELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQFYLLQRTPEVARSRATPLLDLIKTALTPHPPQKQAYGVTLPTSVLFIAGHDTNLANLGGALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNTPPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL 7z2t A 1.41 BS01 IHS A 1 R16 H17 R20 K24 R92 M216 E219 H250 F254 H303 A304 R12 H13 R16 K20 R88 M212 E215 H246 F250 H299 A300 3.1.3.-,3.6.1.- 0003924,0003993,0008252,0008707,0016036,0016787,0030288,0042597,0050308,0052745,0071454 P07102 35683026 501 ELKLESVVIVSRHGVRAPTKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQSGQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNANVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLKREKQDESCSLTQALPSELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQFYLLQRTPEVARSRATPLLDLIKTALTPHPPQKQAYGVTLPTSVLFIAGHATNLANLGGALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNTPPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL 7z2w A 1.42 BS01 IHS A 1 R16 H17 R20 T23 K24 R92 M216 E219 H250 F254 H303 A304 E305 R12 H13 R16 T19 K20 R88 M212 E215 H246 F250 H299 A300 E301 3.1.3.-,3.6.1.- 0003924,0003993,0008252,0008707,0016036,0016787,0030288,0042597,0050308,0052745,0071454 P07102 35683026 501 ELKLESVVIVSRHGVRAPTKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQSGQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNANVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLKREKQDESCSLTQALPSELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQFYLLQRTPEVARSRATPLLDLIKTALTPHPPQKQAYGVTLPTSVLFIAGHAENLANLGGALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNTPPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL 7z2y A 1.86 BS01 IHS A 1 R340 S342 N386 A387 Q388 R335 S337 N381 A382 Q383 3.1.3.-,3.6.1.- 0003924,0003993,0008252,0008707,0016036,0016787,0030288,0042597,0050308,0052745,0071454 P07102 35683026 501 LKLESVVIVSRHGVRAPTKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQSGQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNANVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLKREKQDESCSLTQALPSELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQFYLLQRTPEVARSRATPLLDLIKTALTPHPPQKQAYGVTLPTSVLFIAGHDENLANLGGALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNTPPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL 7z2y A 1.86 BS02 IHS A 2 R16 H17 R20 T23 K24 R92 M216 E219 F254 H303 D304 E305 R11 H12 R15 T18 K19 R87 M211 E214 F249 H298 D299 E300 3.1.3.-,3.6.1.- 0003924,0003993,0008252,0008707,0016036,0016787,0030288,0042597,0050308,0052745,0071454 P07102 35683026 502 LKLESVVIVSRHGVRAPTKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQSGQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNANVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLKREKQDESCSLTQALPSELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQFYLLQRTPEVARSRATPLLDLIKTALTPHPPQKQAYGVTLPTSVLFIAGHDENLANLGGALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNTPPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL 7z3v A 2.6 BS01 IHS A 1 R16 H17 R20 T23 K24 R92 M216 E219 H250 F254 H303 E304 R11 H12 R15 T18 K19 R87 M210 E213 H244 F248 H297 E298 3.1.3.-,3.6.1.- 0003924,0003993,0008252,0008707,0016036,0016787,0030288,0042597,0050308,0052745,0071454 P07102 35683026 501 LKLESVVIVSRHGVRAPTKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQSGQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNANVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLKREKDESCSLTQALPSELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQFYLLQRTPEVARSRATPLLDLIKTALTPHPPQKQAYGVTLPTSVLFIAGHETNLANLGGALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNTPPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL 7z3v A 2.6 BS02 IHS A 2 T26 Q27 L28 T21 Q22 L23 3.1.3.-,3.6.1.- 0003924,0003993,0008252,0008707,0016036,0016787,0030288,0042597,0050308,0052745,0071454 P07102 35683026 502 LKLESVVIVSRHGVRAPTKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQSGQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNANVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLKREKDESCSLTQALPSELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQFYLLQRTPEVARSRATPLLDLIKTALTPHPPQKQAYGVTLPTSVLFIAGHETNLANLGGALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNTPPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL 7zgh A 1.41 BS01 IHS A 1 S11 K12 R41 H42 R45 R138 H174 H320 A321 S7 K8 R37 H38 R41 R134 H170 H316 A317 501 TAQYSTSKTPYSPQQDIRTYQPPPPGFTAVFTELVSRHGSRTPTKIDGADLLLQLWAKARDESELTSAGQDFGPTMESYRAAIQKVGLGQETGRGRQELQGMADRMQRRLPELFEKIKKDATPIAVVLSQQTGRIADTAKFFTARLGATDPALAPLIQQPVVDQDLLYFHKTERGKAYRDYLENDQRYQETVKRIKNRDGTREAATDILKTIFTPAFVERMEPSAVTKAAQALYDLDAIAPDLSVEGNWHLDRFVPRHAAAWFASIDDAKSFYKKGPGFEGSDITFAMASILLDDFFKQAEAARAGKLGADLRFTHAEEIIPLAALMQLPGSEKQADPDEDYTYANNPWRGASVSPMAANLQWDIYRNGTTYLVRMLYQEKEIPFKPDCTPFTPGSHYYRLDELSRCFGRTAR 7zgh B 1.41 BS01 IHS B 1 S11 K12 R41 H42 R45 R138 Y172 H174 H320 A321 S7 K8 R37 H38 R41 R134 Y168 H170 H316 A317 501 TAQYSTSKTPYSPQQDIRTYQPPPPGFTAVFTELVSRHGSRTPTKIDGADLLLQLWAKARDESELTSAGQDFGPTMESYRAAIQKVGLGQETGRGRQELQGMADRMQRRLPELFEKIKKDATPIAVVLSQQTGRIADTAKFFTARLGATDPALAPLIQQPVVDQDLLYFHKTERGKAYRDYLENDQRYQETVKRIKNRDGTREAATDILKTIFTPAFVERMEPSAVTKAAQALYDLDAIAPDLSVEGNWHLDRFVPRHAAAWFASIDDAKSFYKKGPGFEGSDITFAMASILLDDFFKQAEAARAGKLGADLRFTHAEEIIPLAALMQLPGSEKQADPDEDYTYANNPWRGASVSPMAANLQWDIYRNGTTYLVRMLYQEKEIPFKPDCTPFTPGSHYYRLDELSRCFGRTAR