5jq5 A 1.94 BS01 I74 A 1 I10 V18 A31 F80 F82 L83 Q85 N132 L134 A144 D145 I8 V16 A29 F69 F71 L72 Q74 N121 L123 A133 D134 D127 K129 Q131 N132 D145 T158 T165 D116 K118 Q120 N121 D134 T147 T154 2.7.11.22 0000082,0000086,0000122,0000287,0000307,0000781,0000793,0000805,0000806,0001673,0004672,0004674,0004693,0005515,0005524,0005634,0005635,0005654,0005667,0005737,0005768,0005813,0005829,0005856,0006260,0006281,0006338,0006351,0006468,0006813,0007099,0007165,0007265,0007346,0008284,0010389,0010468,0015030,0016301,0016310,0018105,0019904,0030332,0031453,0031571,0032298,0035173,0043247,0043687,0045740,0045893,0046872,0051298,0051301,0051321,0071732,0090398,0097123,0097124,0097134,0097135,0097472,0106310,1905784 Kd=2341nM -logKd/Ki=5.63, Kd=2341nM IC50=620nM P24941 28125165 302 NFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 7b5o J 2.5 BS01 I74 J 1 L18 A39 F91 M94 T96 D97 N141 L144 L9 A30 F77 M80 T82 D83 N127 L130 D137 K139 N142 D155 A168 T175 D123 K125 N128 D141 A154 T161 2.7.11.22,2.7.11.23 0000307,0000439,0001650,0001673,0004672,0004674,0004693,0005515,0005524,0005634,0005654,0005675,0005737,0005829,0005886,0006281,0006366,0006367,0006468,0008094,0008353,0016301,0016310,0042795,0045944,0048471,0050821,0051301,0051726,0070516,0070985,0106310,2000045 IC50=40nM P50613 33476598 401 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPN 7b5q J 2.5 BS01 I74 J 1 A39 F91 M94 T96 D97 N141 L144 A30 F77 M80 T82 D83 N127 L130 D137 K139 N142 D155 A168 T175 D123 K125 N128 D141 A154 T161 2.7.11.22,2.7.11.23 0000307,0000439,0001650,0001673,0004672,0004674,0004693,0005515,0005524,0005634,0005654,0005675,0005737,0005829,0005886,0006281,0006366,0006367,0006468,0008094,0008353,0016301,0016310,0042795,0045944,0048471,0050821,0051301,0051726,0070516,0070985,0106310,2000045 IC50=40nM P50613 33476598 401 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPN 8p6v J 1.9 BS01 I74 J 1 A39 F91 M94 T96 D97 N141 L144 A24 F67 M70 T72 D73 N117 L120 2.7.11.22,2.7.11.23 0000307,0000439,0001650,0001673,0004672,0004674,0004693,0005515,0005524,0005634,0005654,0005675,0005737,0005829,0005886,0006281,0006366,0006367,0006468,0008094,0008353,0016301,0016310,0042795,0045944,0048471,0050821,0051301,0051726,0070516,0070985,0106310,2000045 P50613 38480681 401 KRYEKLDFLGEGQFATVYKARIVAIKKKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRP 8r9a A 1.71 BS01 I74 A 1 V26 A39 F91 M94 E95 T96 D97 N141 N142 V15 A28 F65 M68 E69 T70 D71 N115 N116 2.7.11.22,2.7.11.23 0000307,0000439,0001650,0001673,0004672,0004674,0004693,0005515,0005524,0005634,0005654,0005675,0005737,0005829,0005886,0006281,0006366,0006367,0008094,0008353,0016301,0016310,0042795,0045944,0048471,0050821,0051301,0051726,0070516,0070985,0106310,2000045 P50613 38870939 402 KRYEKLDFLGEGATVYKARDKNTNQIVAIKKNRTALREIKLLQELSHPNIIGLLDAFGSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHRILHRDLKPNNLLLDENGVLKLADFGLAKSFGDPNRAYEHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPN 8ru8 A 1.51 BS01 I74 A 1 L10 V18 A31 F82 L83 H84 N131 L134 D145 L10 V18 A31 F73 L74 H75 N122 L125 D136 0000082,0000086,0000122,0000287,0000307,0000781,0000793,0000805,0000806,0001673,0004672,0004674,0004693,0005515,0005524,0005634,0005635,0005654,0005667,0005737,0005768,0005813,0005829,0005856,0006260,0006281,0006338,0006351,0006468,0006813,0007099,0007165,0007265,0007346,0008284,0010389,0010468,0015030,0016301,0016310,0018105,0019904,0030332,0031453,0031571,0032298,0035173,0043247,0043687,0045740,0045893,0046872,0051298,0051301,0051321,0071732,0090398,0097123,0097124,0097134,0097135,0097472,0106310,1905784 P24941 38870939 301 MENFQKVEKLGEGQYGVVYKARNKLTGEVVALKKIRSTAIREISLLKELNHPNIIKLLDVIHTENKLYLVFEFLHQDLEVFMKASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPNNLLINTEGAIKLADFHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL