6e6e A 2.15 BS01 HVY A 1 L276 G279 C280 V284 A296 K298 V326 I339 T341 Y343 M344 G347 L396 L16 G19 C20 V24 A36 K38 V66 I79 T81 Y83 M84 G87 L136 D389 R391 A393 N394 D407 D129 R131 A133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 IC50=3.0nM P12931 32509799 601 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 6e6e B 2.15 BS01 HVY B 1 L276 G279 C280 V284 A296 K298 M317 V326 I339 T341 Y343 M344 G347 L396 L16 G19 C20 V24 A36 K38 M57 V66 I79 T81 Y83 M84 G87 L136 D389 R391 A393 N394 D407 D129 R131 A133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 IC50=3.0nM P12931 32509799 601 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 6e6e C 2.15 BS01 HVY C 1 L276 G279 C280 V284 A296 K298 V326 I339 T341 M344 G347 N394 L396 L16 G19 C20 V24 A36 K38 V66 I79 T81 M84 G87 N134 L136 D389 R391 A393 N394 D407 D129 R131 A133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 IC50=3.0nM P12931 32509799 601 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 6e6e D 2.15 BS01 HVY D 1 L276 G279 C280 V284 A296 K298 M317 V326 I339 T341 Y343 M344 G347 L396 A406 L16 G19 C20 V24 A36 K38 M57 V66 I79 T81 Y83 M84 G87 L136 A146 D389 R391 A393 N394 D407 D129 R131 A133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 IC50=3.0nM P12931 32509799 601 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 6e6e E 2.15 BS01 HVY E 1 L276 G279 C280 V284 A296 K298 E313 M317 V326 I339 T341 Y343 M344 G347 L396 A406 L16 G19 C20 V24 A36 K38 E53 M57 V66 I79 T81 Y83 M84 G87 L136 A146 D389 R391 A393 N394 D407 D129 R131 A133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 IC50=3.0nM P12931 32509799 601 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 6e6e F 2.15 BS01 HVY F 1 L276 G279 C280 V284 A296 K298 V326 I339 T341 Y343 M344 G347 L396 A406 L16 G19 C20 V24 A36 K38 V66 I79 T81 Y83 M84 G87 L136 A146 D389 R391 A393 N394 D407 D129 R131 A133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 IC50=3.0nM P12931 32509799 601 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 6e6e G 2.15 BS01 HVY G 1 L276 G279 C280 V284 A296 K298 M317 V326 I339 T341 Y343 M344 G347 L396 A406 L16 G19 C20 V24 A36 K38 M57 V66 I79 T81 Y83 M84 G87 L136 A146 D389 R391 A393 N394 D407 D129 R131 A133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 IC50=3.0nM P12931 32509799 601 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 6e6e H 2.15 BS01 HVY H 1 L276 G279 C280 V284 A296 I297 K298 V326 T341 M344 G347 L396 L16 G19 C20 V24 A36 I37 K38 V66 T81 M84 G87 L136 D389 R391 A393 N394 D407 D129 R131 A133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 IC50=3.0nM P12931 32509799 601 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL