2c6e A 2.1 BS01 HPM A 1 K161 Q184 L209 A212 P213 G215 L262 D273 F274 W276 K36 Q59 L84 A87 P88 G90 L137 D148 F149 W151 D255 K257 E259 N260 D273 T291 D130 K132 E134 N135 D148 T154 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 -logKd/Ki=9.10, IC50=0.8nM IC50=0.80nM O14965 16337122 1389 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 2c6e B 2.1 BS01 HPM B 1 R136 L138 K161 Q184 L193 L207 A212 P213 L262 D273 R11 L13 K36 Q59 L68 L82 A87 P88 L137 D148 D255 K257 E259 N260 D273 T291 D130 K132 E134 N135 D148 T150 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 IC50=0.80nM O14965 16337122 1388 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS