4bb5	A	2.2	BS02	HD2	A	1	L126 S170 V180 Y183 G216 L217 A226	L100 S144 V154 Y157 G190 L191 A200	S170 Y183 K187	S144 Y157 K161	1.1.1.146,1.1.1.201	0005496,0005783,0005789,0006706,0008202,0016020,0016491,0030324,0042803,0043231,0047022,0050661,0070524,0102196		ic50=21nM			P28845	23153367	1291 	FRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPLVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPSRKILEELYSTSYNMDRF
4bb5	A	2.2	BS03	HD2	B	1	Y280 Y284	Y254 Y258	S170 Y183 K187	S144 Y157 K161	1.1.1.146,1.1.1.201	0005496,0005783,0005789,0006706,0008202,0016020,0016491,0030324,0042803,0043231,0047022,0050661,0070524,0102196		ic50=21nM			P28845	23153367	1291 	FRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPLVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPSRKILEELYSTSYNMDRF
4bb5	B	2.2	BS02	HD2	B	1	L126 S170 Y177 V180 Y183 G216 L217	L101 S145 Y152 V155 Y158 G191 L192	S170 Y183 K187	S145 Y158 K162	1.1.1.146,1.1.1.201	0005496,0005783,0005789,0006706,0008202,0016020,0016491,0030324,0042803,0043231,0047022,0050661,0070524,0102196		ic50=21nM			P28845	23153367	1291 	EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPLVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPSRKILEELYSTSYNMDRF
4bb5	C	2.2	BS02	HD2	C	1	L126 S170 L171 Y177 V180 Y183 G216 L217 M233	L101 S145 L146 Y152 V155 Y158 G191 L192 M208	S170 Y183 K187	S145 Y158 K162	1.1.1.146,1.1.1.201	0005496,0005783,0005789,0006706,0008202,0016020,0016491,0030324,0042803,0043231,0047022,0050661,0070524,0102196		ic50=21nM			P28845	23153367	1281 	EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPLVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPSRKILEEL
4bb5	D	2.2	BS01	HD2	C	1	Y280 Y284	Y252 Y256	S170 Y183 K187	S145 Y158 K162	1.1.1.146,1.1.1.201	0005496,0005783,0005789,0006706,0008202,0016020,0016491,0030324,0042803,0043231,0047022,0050661,0070524,0102196		ic50=21nM			P28845	23153367	1281 	EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPLVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPSRKILEELYSTSYNMDRFI
4bb5	D	2.2	BS03	HD2	D	1	S170 Y177 V180 Y183 G216 A223 A226 M233	S145 Y152 V155 Y158 G191 A198 A201 M205	S170 Y183 K187	S145 Y158 K162	1.1.1.146,1.1.1.201	0005496,0005783,0005789,0006706,0008202,0016020,0016491,0030324,0042803,0043231,0047022,0050661,0070524,0102196		ic50=21nM			P28845	23153367	1292 	EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPLVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPSRKILEELYSTSYNMDRFI
5alu	A	1.87	BS01	HD2	A	1	D11 F20 F41 T51 N124	D10 F19 F40 T50 N123	F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524	F266 H333 D334 W335 N358 N377 Y382 Y465 D495 H523	3.1.3.76,3.3.2.10	0000287,0003824,0004301,0005737,0005777,0005782,0005829,0006629,0009056,0009636,0010628,0015643,0016311,0016787,0016791,0033885,0042577,0042632,0042803,0046272,0046839,0046872,0052642,0070062,0090181,0097176		ic50=0.022uM	-logKd/Ki=7.66, IC50=0.022uM		P34913	25931264	1548 	TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR
5alu	A	1.87	BS02	HD2	A	2	I363 N366 F381 Q384 M503	I362 N365 F380 Q383 M502	F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524	F266 H333 D334 W335 N358 N377 Y382 Y465 D495 H523	3.1.3.76,3.3.2.10	0000287,0003824,0004301,0005737,0005777,0005782,0005829,0006629,0009056,0009636,0010628,0015643,0016311,0016787,0016791,0033885,0042577,0042632,0042803,0046272,0046839,0046872,0052642,0070062,0090181,0097176		ic50=0.022uM	-logKd/Ki=7.66, IC50=0.022uM		P34913	25931264	1551 	TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR
5alu	A	1.87	BS03	HD2	A	3	D335 W336 Y383 Q384 Y466 V498 L499 H524	D334 W335 Y382 Q383 Y465 V497 L498 H523	F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524	F266 H333 D334 W335 N358 N377 Y382 Y465 D495 H523	3.1.3.76,3.3.2.10	0000287,0003824,0004301,0005737,0005777,0005782,0005829,0006629,0009056,0009636,0010628,0015643,0016311,0016787,0016791,0033885,0042577,0042632,0042803,0046272,0046839,0046872,0052642,0070062,0090181,0097176		ic50=0.022uM	-logKd/Ki=7.66, IC50=0.022uM		P34913	25931264	1554 	TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR