6hzu A 2.2 BS01 GYQ A 1 L881 G882 E883 G887 V889 A906 M956 E957 F958 G962 E966 L1010 D1021 L29 G30 E31 G35 V37 A54 M96 E97 F98 G102 E106 L150 D161 D1003 A1005 R1007 N1008 D1021 D143 A145 R147 N148 D161 2.7.10.2 0004672,0004713,0005524,0006468 ic50=5.5nM -logKd/Ki=8.26, IC50=5.5nM P23458 31609613 1201 GDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPNHIADLKKEIEILRNLYHENIVKYKGICTNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK 6hzu B 2.2 BS01 GYQ B 1 L881 G882 G884 G887 V889 A906 K908 M956 E957 F958 G962 E966 L1010 D1021 L17 G18 G20 G23 V25 A42 K44 M87 E88 F89 G93 E97 L141 D152 D1003 A1005 R1007 N1008 D1021 D134 A136 R138 N139 D152 2.7.10.2 0004672,0004713,0005524,0006468 ic50=5.5nM P23458 31609613 1201 VDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK