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BioLiP
Download all results in tab-seperated text for 17 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1mqi:A (1.35) BS01 FWD ? GO:0015276 ... P19491 12872125 MOAD: ic50=23.53nM
    PDBbind: -logKd/Ki=7.63, IC50=23.53nM
    BindingDB: Ki=4nM, EC50=460nM
    2 2al5:A (1.65) BS01 FWD ? GO:0015276 ... P19491 16192394 PDBbind: -logKd/Ki=8.40, Ki=4nM
    BindingDB: Ki=4nM, EC50=460nM
    3 2al5:B (1.65) BS02 FWD ? GO:0015276 ... P19491 16192394 BindingDB: Ki=4nM, EC50=460nM
    4 3rt6:B (2.836) BS01 FWD ? GO:0015276 ... P19492 21464198 PDBbind: -logKd/Ki=7.15, Ki=70nM
    BindingDB: Ki=18nM, EC50=20900nM
    5 4u1y:A (3.8999) BS01 FWD ? GO:0000149 ... P19491 25109876 BindingDB: Ki=4nM, EC50=460nM
    6 4u1y:B (3.8999) BS01 FWD ? GO:0000149 ... P19491 25109876 BindingDB: Ki=4nM, EC50=460nM
    7 4u1y:C (3.8999) BS02 FWD ? GO:0000149 ... P19491 25109876 BindingDB: Ki=4nM, EC50=460nM
    8 4u1y:D (3.8999) BS02 FWD ? GO:0000149 ... P19491 25109876 BindingDB: Ki=4nM, EC50=460nM
    9 4u21:A (1.3908) BS01 FWD ? GO:0015276 ... P19491 25109876 BindingDB: Ki=4nM, EC50=460nM
    10 4u21:B (1.3908) BS01 FWD ? GO:0015276 ... P19491 25109876 BindingDB: Ki=4nM, EC50=460nM
    11 4u22:A (1.4409) BS01 FWD ? GO:0015276 ... P19491 25109876 BindingDB: Ki=4nM, EC50=460nM
    12 4u23:A (1.6734) BS01 FWD ? GO:0015276 ... P19491 25109876 BindingDB: Ki=4nM, EC50=460nM
    13 4u5c:A (3.6883) BS01 FWD ? GO:0000149 ... P19491 25103405 BindingDB: Ki=4nM, EC50=460nM
    14 4u5c:B (3.6883) BS01 FWD ? GO:0000149 ... P19491 25103405 BindingDB: Ki=4nM, EC50=460nM
    15 4u5c:C (3.6883) BS02 FWD ? GO:0000149 ... P19491 25103405 BindingDB: Ki=4nM, EC50=460nM
    16 4u5c:D (3.6883) BS01 FWD ? GO:0000149 ... P19491 25103405 BindingDB: Ki=4nM, EC50=460nM
    17 5jei:A (1.229) BS01 FWD ? GO:0015276 ... P19491 28211453 BindingDB: Ki=4nM, EC50=460nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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