1dgp A 2.8 BS01 FOF A 1 F112 R200 K206 S241 N244 F73 R161 K167 S202 N205 Y92 F112 F178 K206 W333 Y53 F73 F139 K167 W285 4.2.3.9 Q03471 10825154 401 TPPPTQWSYLCHPRVKEVQDEVDGYFLENWKFPSFKAVRTFLDAKFSEVTCLYFPLALDDRIHFACRLLTVLFLIDDVLEHMSFADGEAYNNRLIPISRGDVLPDRTKPEEFILYDLWESMRAHDAELANEVLEPTFVFMRAQTDRARLSIHELGHYLEYREKDVGKALLSALMRFSMGLRLSADELQDMKALEANCAKQLSVVNDIYSYDKEEEALCSAVKVLAEESKLGIPATKRVLWSMTREWETVHDEIVAEKIASPDGCSEAAKAYMKGLEYQMSGNEQWSKTTR 1dgp B 2.8 BS01 FOF B 1 F112 R200 K206 S241 N244 D245 F73 R161 K167 S202 N205 D206 Y92 F112 F178 K206 W333 Y53 F73 F139 K167 W285 4.2.3.9 Q03471 10825154 401 TPPPTQWSYLCHPRVKEVQDEVDGYFLENWKFPSFKAVRTFLDAKFSEVTCLYFPLALDDRIHFACRLLTVLFLIDDVLEHMSFADGEAYNNRLIPISRGDVLPDRTKPEEFILYDLWESMRAHDAELANEVLEPTFVFMRAQTDRARLSIHELGHYLEYREKDVGKALLSALMRFSMGLRLSADELQDMKALEANCAKQLSVVNDIYSYDKEEEALCSAVKVLAEESKLGIPATKRVLWSMTREWETVHDEIVAEKIASPDGCSEAAKAYMKGLEYQMSGNEQWSKTTR 2bk3 A 1.8 BS02 FOF A 1 L171 I199 Q206 Y398 L169 I197 Q204 Y396 G62 R197 K296 G60 R195 K294 1.4.3.21,1.4.3.4 0005515,0005739,0005740,0005741,0008131,0009055,0009410,0009636,0010044,0010269,0014063,0016491,0019607,0021762,0030425,0032496,0042420,0042802,0043025,0045471,0045964,0048545,0050660,0050665,0051412,0052595,0097621 Ki=2.3uM P27338 15710600 1503 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTI 2bk3 B 1.8 BS02 FOF B 1 L171 I199 Q206 Y398 L169 I197 Q204 Y396 G62 R197 K296 G60 R195 K294 1.4.3.21,1.4.3.4 0005515,0005739,0005740,0005741,0008131,0009055,0009410,0009636,0010044,0010269,0014063,0016491,0019607,0021762,0030425,0032496,0042420,0042802,0043025,0045471,0045964,0048545,0050660,0050665,0051412,0052595,0097621 Ki=2.3uM P27338 15710600 1498 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLI 6dew A 2.0 BS01 FOF A 1 V150 N154 L207 M208 L217 M223 V58 N62 L115 M116 L125 M131 ? 0006744,0008289 O75208 30661980 304 YESEEQLQHRILTAALEFVPAHGWTAEAIAEGAQSLGLSSAAASMFGKDGSELILHFVTQCNTRLTRVLEEEQKLVQLGQAEKRKTDQFLRDAVETRLRMLIPYIEHWPRALSILMLPHNIPSSLSLLTSMVDDMWHYAGDQSTDFNWYTRRAMLAAIYNTTELVMMQDSSPDFEDTWRFLENRVNDAMNMGHTA 6nux A 2.2 BS01 FOF A 1 W14 F70 V98 W6 F61 V89 ? P06126 31901073 301 SFHVIWIASFYNHSWKQNLVSGWLSDLQTHTWDSNSSTIVFLWPWSRGNFSNEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCESGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEGSLVPRG 8fkb A 1.42 BS01 FOF A 1 F107 A267 M318 F102 A262 M313 ? 0004497,0005506,0006707,0008395,0016705,0020037,0036199,0046872 B2HHT9 36842492 505 GLLPRVNGTPPPEVPLADIELGSLEFWGRDDDFRDGAFATLRREAPISFWPPIELAGLTAGKGHWALTKHDDIHFASRHPEIFHSSPNIVIHDQTPELAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEASVRERAHRLVAAMIENHPDGQADLVSELAGPLPLQIICDMMGIPEEDHEQIFHWTNVILGFGDPDLTTDFDEFLQVSMAIGGYATALADDRRVNHHGDLTTSLVEAEVDGERLSSSEIAMFFILLVVAGNETTRNAISHGMLALSRYPDERAKWWSDFDGLAATAVEEIVRWASPVVYMRRTLSQDVDLRGTKMAAGDKVTLWYCSANRDEEKFADPWTFDVTRNPNPQVGFGGGGAHFCLGANLARREIRVVFDELRRQMPDVVATEEPARLLSQFIHGIKRLPVAWSR