6ckc A 2.8 BS01 F5J A 1 P314 L315 L319 Y324 F327 G365 E392 K393 D419 M420 E435 L436 C449 P302 L303 L307 Y312 F315 G353 E380 K381 D407 M408 E423 L424 C437 2.1.1.320 0000387,0000785,0002039,0003714,0005515,0005634,0005654,0005694,0005737,0005794,0005829,0006325,0006338,0006353,0006355,0006479,0007088,0008168,0008327,0008469,0010468,0016274,0018216,0032259,0032922,0032991,0034709,0035097,0035243,0035246,0042054,0042118,0042802,0043021,0044020,0044027,0044877,0045596,0045892,0046982,0048026,0048511,0048714,0070372,0070888,0090161,0097421,0140938,1901796,1904992 -logKd/Ki=8.22, Kd=6nM IC50=25nM, Kd=6.0nM, EC50=40nM O14744 30034588 701 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL