6gcr A 2.3 BS01 EUW A 1 C427 I428 G429 A452 L501 C502 G505 E506 L553 D564 L567 C15 I16 G17 A40 L89 C90 G93 E94 L141 D152 L155 D546 A548 R550 N551 D564 D134 A136 R138 N139 D152 2.7.10.2 0004672,0004713,0005524,0006468 -logKd/Ki=8.33, IC50=4.7nM Q00944 29897729 701 RDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPAMAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKFSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSATDCVKLGDFGLSRLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 6gcx A 1.553 BS01 EUW A 1 R426 L501 C502 T503 G505 L553 L567 R14 L87 C88 T89 G91 L139 L153 D546 A548 R550 N551 D564 D132 A134 R136 N137 D150 2.7.10.2 0004672,0004713,0005524,0006468 ic50=0.6nM -logKd/Ki=9.22, IC50=0.6nM Q00944 29897729 701 RDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPAMAVAIKTCKNSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKFSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSATDCVKLGDFGLSRLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKLQ