1c5n H 1.5 BS03 ESI H 1 D189 S195 G216 G219 D192 S198 G221 G223 3.4.21.5 0004252,0005509,0006508,0007596 Ki=20uM -logKd/Ki=4.70, Ki=20uM Ki=20000nM P00734 10779411 522 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 1c5q A 1.43 BS02 ESI A 1 D189 S190 S195 W215 G216 G219 C220 D171 S172 S177 W193 G194 G196 C197 H57 D102 Q192 G193 D194 S195 G196 H40 D84 Q174 G175 D176 S177 G178 3.4.21.4 0004175,0004252,0005515,0005576,0005615,0006508,0007586,0008236,0046872,0097180,0097655 Ki=0.44uM -logKd/Ki=6.36, Ki=0.44uM Ki=440nM P00760 10779411 246 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 1c5r A 1.47 BS02 ESI A 1 D189 S190 C191 Q192 S195 W215 G216 G219 D171 S172 C173 Q174 S177 W193 G194 G196 H57 D102 Q192 G193 D194 S195 G196 H40 D84 Q174 G175 D176 S177 G178 3.4.21.4 0004175,0004252,0005515,0005576,0005615,0006508,0007586,0008236,0046872,0097180,0097655 Ki=440nM P00760 10779411 246 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 1c5w B 1.94 BS02 ESI B 1 D189 S190 Q192 S195 W215 G216 G219 C220 D192 S193 Q195 S198 W218 G219 G221 C222 H57 D102 Q192 G193 D194 S195 G196 H46 D97 Q195 G196 D197 S198 G199 3.4.21.73 0004252,0006508 Ki=210nM P00749 10779411 251 IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLMSPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKEASTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEE 1c5x B 1.75 BS02 ESI B 1 D189 S190 Q192 S195 W215 G216 G219 C220 G226 D192 S193 Q195 S198 W218 G219 G221 C222 G229 H57 D102 Q192 G193 D194 S195 G196 H46 D97 Q195 G196 D197 S198 G199 3.4.21.73 0004252,0006508 Ki=0.21uM -logKd/Ki=6.68, Ki=0.21uM Ki=210nM P00749 10779411 251 IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLMSPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKEASTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEE 1o5b B 1.85 BS02 ESI B 1 D189 A190 Q192 S195 W215 G216 G219 D192 A193 Q195 S198 W218 G219 G221 H57 D102 Q192 G193 D194 S195 G196 H46 D97 Q195 G196 D197 S198 G199 3.4.21.73 0004252,0006508 Ki=1.7uM -logKd/Ki=5.77, Ki=1.7uM Ki=210nM P00749 15522303 251 IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLMSPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKEASTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDACQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHT