3e37 B 1.8 BS03 ED5 B 1 W104 Y156 R204 Y207 G252 C256 D299 W305 D361 Y363 H364 W88 Y140 R188 Y191 G236 C240 D283 W289 D345 Y347 H348 H250 R293 K296 D299 C301 Y302 D354 D361 H364 H234 R277 K280 D283 C285 Y286 D338 D345 H348 2.5.1.58 0003824,0004659,0004660,0005515,0005829,0005875,0005965,0006629,0008270,0008318,0018343,0046872 ic50=4050nM -logKd/Ki=5.39, IC50=4.05uM P49356 19246009 1 SSPVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATTYFLQKPVPGFE 4lnb B 1.752 BS03 ED5 B 1 A168 L169 R274 D387 C389 D452 Y454 H455 A79 L80 R185 D298 C300 D360 Y362 H363 H333 R381 K384 D387 C389 Y390 D445 D452 H455 H244 R292 K295 D298 C300 Y301 D353 D360 H363 2.5.1.58 0003824,0004659,0004660,0005965,0008270,0008318,0016853,0018343,0046872,0097354 -logKd/Ki=6.56, IC50=275nM Q4WPS9 24347326 603 VHPGIPALFREPPLIHDLLSTETTELQSETVNKCLPLLKGIHNSQKGPFNKYGIPALQRKDHLEYLYDSLEDYPASFVALDASRPWMVYWALAGLCLLGEDVTRFRERVISTFTAAQNSTGGIGGGHGQMSHVASSYAAVLSIAMVGGEEAFKLIDRKAMWKWLGKLKQPDGGFTVCEGGEEDVRGAYCAMVVHALLDLPLALPPEAEARQNGLETFTDGLPEYLSRCQTYEGGISGSPGSEAHGAYAFCALACLCLLGRPEVVVPRYMNIATLLPWLSARQYAPEGGFSGRTNKLVDGCYSHWVGNCWPLVQAALDGTQPLARSSVGNLYSREGLTRYILSCCQCKLGGLRDKPGKHPDSYHTCYALTGLSTVQYYHYCTDSSVSSKFSSAFSWKHDPNFASDGQGSDIGVFTENDRLVPFHPIFVIPHKSAEDIRVWFENQSFDL