6fug A 2.21 BS01 E85 A 1 I143 H146 D189 S190 C191 K192 S195 V213 R218 V219 C220 I125 H128 D166 S167 C168 K169 S172 V186 R188 V189 C190 H57 D102 K192 G193 D194 S195 G196 H41 D84 K169 G170 D171 S172 G173 3.4.21.46 0004252,0005576,0005615,0006508,0006956,0006957,0008236,0009617,0031093,0034774,0070062,1904813 Kd=50uM -logKd/Ki=4.30, Kd=50uM IC50=20000nM, Kd=50000nM P00746 29795765 301 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTRVCGNRKKPGIYTRVASYAAWIDSVLASA 6fug B 2.21 BS01 E85 B 1 H146 D189 S190 C191 K192 S195 R218 V219 C220 H129 D164 S165 C166 K167 S170 R186 V187 C188 H57 D102 K192 G193 D194 S195 G196 H41 D85 K167 G168 D169 S170 G171 3.4.21.46 0004252,0005576,0005615,0006508,0006956,0006957,0008236,0009617,0031093,0034774,0070062,1904813 Kd=50uM IC50=20000nM, Kd=50000nM P00746 29795765 301 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNTERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTRVCGNRKKPIYTRVASYAAWIDSVLA 6fug C 2.21 BS01 E85 C 1 I143 H146 D189 S190 C191 K192 S195 R218 V219 C220 I126 H129 D168 S169 C170 K171 S174 R190 V191 C192 H57 D102 K192 G193 D194 S195 G196 H41 D85 K171 G172 D173 S174 G175 3.4.21.46 0004252,0005576,0005615,0006508,0006956,0006957,0008236,0009617,0031093,0034774,0070062,1904813 Kd=50uM IC50=20000nM, Kd=50000nM P00746 29795765 301 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTRVCGNRKKPGIYTRVASYAAWIDSVLASA 6fug D 2.21 BS01 E85 D 1 I143 H146 D189 S190 C191 K192 S195 V213 T214 R218 C220 I126 H129 D164 S165 C166 K167 S170 V184 T185 R186 C188 H57 D102 K192 G193 D194 S195 G196 H41 D85 K167 G168 D169 S170 G171 3.4.21.46 0004252,0005576,0005615,0006508,0006956,0006957,0008236,0009617,0031093,0034774,0070062,1904813 Kd=50uM IC50=20000nM, Kd=50000nM P00746 29795765 301 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNTERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTRVCGNRKKPGIYTRVASYAAWIDSVLASA 6fug E 2.21 BS01 E85 E 1 H146 S190 C191 K192 C220 H129 S165 C166 K167 C187 H57 D102 K192 G193 D194 S195 G196 H41 D85 K167 G168 D169 S170 G171 3.4.21.46 0004252,0005576,0005615,0006508,0006956,0006957,0008236,0009617,0031093,0034774,0070062,1904813 Kd=50uM IC50=20000nM, Kd=50000nM P00746 29795765 301 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNTERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTVCGNRKKPGIYTRVASYAAWIDSVLASA 6fug F 2.21 BS01 E85 F 1 I143 H146 D189 S190 C191 K192 S195 V213 V219 C220 I126 H129 D164 S165 C166 K167 S170 V184 V186 C187 H57 D102 K192 G193 D194 S195 G196 H41 D85 K167 G168 D169 S170 G171 3.4.21.46 0004252,0005576,0005615,0006508,0006956,0006957,0008236,0009617,0031093,0034774,0070062,1904813 Kd=50uM IC50=20000nM, Kd=50000nM P00746 29795765 301 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNTERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTVCGNRKKPGIYTRVASYAAWIDSVLASA