1c0p A 1.2 BS02 DAL A 1 F1058 Y1223 Y1238 R1285 S1335 F60 Y225 Y240 R287 S337 N1054 S1335 Q1339 N56 S337 Q341 1.4.3.3 0003884,0046416,0071949 P80324 11070076 1364 LMMHSQKRVVVLGSGVIGLSSALILARKGYSVHILARDLPEDVSSQTFASPWAGANWTPFMTLTDGPRQAKWEESTFKKWVELVPTGHAMWLKGTRRFAQNEDGLLGHWYKDITPNYRPLPSSECPPGAIGVTYDTLSVHAPKYCQYLARELQKLGATFERRTVTSLEQAFDGADLVVNATGLGAKSIAGIDDQAAEPIRGQTVLVKSPCKRCTMDSSDPASPAYIIPRPGGEVICGGTYGVGDWDLSVNPETVQRILKHCLRLDPTISSDGTIEGIEVLRHNVGLRPARRGGPRVEAERIVLPLDRTKSPLSLGRGSARAAKEKEVTLVHAYGFSSAGYQQSWGAAEDVAQLVDEAFQRYHG 1iki A 1.25 BS02 DAL A 1 S62 Y159 R285 H298 T299 G300 T301 S60 Y157 R283 H296 T297 G298 T299 S62 K65 D114 T116 V130 Y159 N161 V165 T227 H298 G304 S60 K63 D112 T114 V128 Y157 N159 V163 T225 H296 G302 3.4.16.4 0004180,0005576,0006508,0008360,0009002,0009252,0071555 P15555 12215418 500 LPAPDDTGLQAVLHTALSQGAPGAMVRVDDNGTIHQLSEGVADRATGRAITTTDRFRVGSVTKSFSAVVLLQLVDEGKLDLDASVNTYLPGLLPDDRITVRQVMSHRSGLYDYTNDMFAQTVPGFESVRNKVFSYQDLITLSLKHGVTNAPGAAYSYSNTNFVVAGMLIEKLTGHSVATEYQNRIFTPLNLTDTFYVHPDTVIPGTHANGYLTPDEAGGALVDSTEQTVSWAQSAGAVISSTQDLDTFFSALMSGQLMSAAQLAQMQQWTTVNSTQGYGLGLRRRDLSCGISVYGHTGTVQGYYTYAFASKDGKRSVTALANTSNNVNVLNTMARTLESAFCGKP 1kto A 1.9 BS06 DAL A 1 E143 H146 E166 H231 E143 H146 E166 H231 H142 E143 H146 Y157 E166 D226 H231 H142 E143 H146 Y157 E166 D226 H231 3.4.24.27 0004222,0006508 P00800 1317 ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK 2j9p A 2.8 BS02 DAL A 1 S52 S299 T412 S48 S295 T408 3.4.16.4 0000270,0004185,0005576,0006508,0008360,0009002,0009252,0016020,0016787,0045121,0051301,0071555 P39844 17582436 501 DALSGQIDKILADHPALEGAMAGITVRSAETGAVLYEHSGDTRMRPASSLKLLTAAAALSVLGENYSFTTEVRTDGTLKGKKLNGNLYLKGKGDPTLLPSDFDKMAEILKHSGVKVIKGNLIGDDTWHDDMRLSPDMPWSDEYTYYGAPISALTASPNEDYDAGTVIVEVTPNQKEGEEPAVSVSPKTDYITIKNDAKTTAAGSEKDLTIEREHGTNTITIEGSVPVDANKTKEWISVWEPAGYALDLFKQSLKKQGITVKGDIKTGEAPSSSDVLLSHRSMPLSKLFVPFMKLSNNGHAEVLVKEMGKVKKGEGSWEKGLEVLNSTLPEFGVDSKSLVLRDGSGISHIDAVSSDQLSQLLYDIQDQSWFSAYLNSLPVAGNPDRMVGGTLRNRMKGTPAQGKVRAKTGSLSTVSSLSGYAETKSGKKLVFSILLNGLIDEEDGKDIEDQIAVILANQ 2j9p B 2.8 BS02 DAL B 1 S299 T412 G413 S414 S295 T408 G409 S410 3.4.16.4 0000270,0004185,0005576,0006508,0008360,0009002,0009252,0016020,0016787,0045121,0051301,0071555 P39844 17582436 501 DALSGQIDKILADHPALEGAMAGITVRSAETGAVLYEHSGDTRMRPASSLKLLTAAAALSVLGENYSFTTEVRTDGTLKGKKLNGNLYLKGKGDPTLLPSDFDKMAEILKHSGVKVIKGNLIGDDTWHDDMRLSPDMPWSDEYTYYGAPISALTASPNEDYDAGTVIVEVTPNQKEGEEPAVSVSPKTDYITIKNDAKTTAAGSEKDLTIEREHGTNTITIEGSVPVDANKTKEWISVWEPAGYALDLFKQSLKKQGITVKGDIKTGEAPSSSDVLLSHRSMPLSKLFVPFMKLSNNGHAEVLVKEMGKVKKGEGSWEKGLEVLNSTLPEFGVDSKSLVLRDGSGISHIDAVSSDQLSQLLYDIQDQSWFSAYLNSLPVAGNPDRMVGGTLRNRMKGTPAQGKVRAKTGSLSTVSSLSGYAETKSGKKLVFSILLNGLIDEEDGKDIEDQIAVILANQ 2yzm A 2.21 BS01 DAL A 1 E13 G83 E87 N284 E13 G83 E87 N284 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 401 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALT 2yzm B 2.21 BS01 DAL B 1 E13 G83 E87 M114 E282 N284 E13 G83 E87 M114 E275 N277 E13 V16 L19 H82 S159 R268 D270 E282 N284 G288 T292 E13 V16 L19 H82 S159 R261 D263 E275 N277 G281 T285 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 402 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALT 2yzm C 2.21 BS01 DAL C 1 E13 E87 E282 N284 E13 E87 E271 N273 E13 V16 L19 H82 S159 R268 D270 E282 N284 G288 T292 E13 V16 L19 H82 S159 R257 D259 E271 N273 G277 T281 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 403 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALT 2zdh A 1.9 BS03 DAL A 1 E13 Y229 R268 G288 E13 Y229 R268 G288 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 801 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALT 2zdh D 1.9 BS02 DAL D 1 E13 H82 R268 G288 E13 H82 R268 G288 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 802 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALT 2zdq A 2.3 BS01 DAL A 1 E13 H82 Y229 R268 G288 E13 H82 Y229 R268 G288 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 401 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALT 2zdq A 2.3 BS02 DAL A 2 R268 G288 S293 R268 G288 S293 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 402 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALT 2zdq B 2.3 BS01 DAL B 1 E13 H82 Y229 R268 G288 E13 H82 Y229 R268 G288 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 403 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALT 2zdq B 2.3 BS02 DAL B 2 R268 G288 S293 R268 G288 S293 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 E13 V16 L19 H82 S159 E226 Y229 R268 D270 E282 N284 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 404 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALT 3dhv A 2.0 BS01 DAL A 1 F196 D197 C269 G295 V301 K492 F190 D191 C263 G289 V295 K486 T152 F172 T297 E298 K403 R408 K492 T151 F166 T291 E292 K397 R402 K486 6.2.1.54 0005524,0005737,0016874,0047473,0070395 Q81G39 18847223 701 KLLEQIEKWAAETPDQTAFVWRDAKITYKQLKEDSDALAHWISSEYPDDRSPIMVYGHMQPEMIINFLGCVKAGHAYIPVDLSIPADRVQRIAENSGAKLLLSATAVTVTDLPVRIVSEDNLKDIFFTHKGNTPNPEHAVKGDENFYIIYTSPKGVQITYNCLVSFTKWAVEDFNLQTGQVFLNQAPFSFDLSVMDIYPSLVTGGTLWAIDKDMIARPKDLFASLEQSDIQVWTSTPSFAEMCLMEASFSESMLPNMKTFLFCGEVLPNEVARKLIERFPKATIMNTYGPTEATVAVTGIHVTEEVLDQYKSLPVGYCKSDCRLLIMKEDGTIAPDGEKGEIVIVGPSVSVGYLGSPELTEKAFTMIDGERAYKTGDAGYVENGLLFYNGRLDFQIKLHGYRMELEEIEHHLRACSYVEGAVIVPIKKGEKYDYLLAVVVPGEHSFEKEFKLTSAIKKELNERLPNYMIPRKFMYQSSIPMTPNGKVDRKKLLSEVTA 3q45 A 3.0 BS02 DAL A 1 F19 K162 D318 D320 T321 F19 K162 D318 D320 T321 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2470 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q45 B 3.0 BS02 DAL B 1 F19 K162 D318 D320 F19 K162 D318 D320 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2472 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q45 C 3.0 BS02 DAL C 1 K160 K162 D318 D320 K160 K162 D318 D320 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2474 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q45 D 3.0 BS02 DAL D 1 K162 D318 D320 K162 D318 D320 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2476 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q45 E 3.0 BS02 DAL E 1 K160 K162 D318 D320 K160 K162 D318 D320 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2478 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q45 F 3.0 BS02 DAL F 1 T135 K162 D318 D320 T135 K162 D318 D320 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2480 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q45 G 3.0 BS02 DAL G 1 F19 K162 G293 D318 D320 F19 K162 G293 D318 D320 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2482 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q45 H 3.0 BS02 DAL H 1 F19 T135 K162 D318 D320 F19 T135 K162 D318 D320 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2484 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q45 I 3.0 BS02 DAL I 1 K162 G293 D318 K162 G293 D318 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2486 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q4d A 3.0 BS02 DAL A 1 F19 K162 G293 D318 D320 T321 F19 K162 G293 D318 D320 T321 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2472 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q4d B 3.0 BS02 DAL B 1 F19 K162 D318 D320 T321 F19 K162 D318 D320 T321 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2470 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q4d C 3.0 BS02 DAL C 1 F19 K162 D318 D320 F19 K162 D318 D320 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2474 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q4d D 3.0 BS02 DAL D 1 F19 T135 K162 D318 D320 T321 F19 T135 K162 D318 D320 T321 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2476 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q4d E 3.0 BS02 DAL E 1 F19 K162 D318 D320 F19 K162 D318 D320 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2478 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q4d F 3.0 BS02 DAL F 1 T135 K160 K162 D318 D320 T135 K160 K162 D318 D320 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2480 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q4d G 3.0 BS02 DAL G 1 F19 K162 G293 D318 D320 F19 K162 G293 D318 D320 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2482 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q4d H 3.0 BS02 DAL H 1 F19 K162 G293 D318 D320 F19 K162 G293 D318 D320 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2484 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3q4d I 3.0 BS02 DAL I 1 K162 G293 D318 K162 G293 D318 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 F19 P50 T53 T135 K160 K162 D190 N192 E216 D241 E242 S243 K265 G292 G293 F294 Y317 D318 F319 5.1.1.- 0000287,0006518,0016853,0016854,0016855,0046872 Q11T61 22392983 2486 MIITQVELYKSPVKLKEPFKISLGILTHANNVIVRIHTASGHIGYGECSPFMTIHGESMDTAFIVGQYLAKGLIGTSCLDIVSNSLLMDAIIYGNSCIKSAFNIALYDLAAQHAGLPLYAFLGGKKDKIIQTDYTVSIDEPHKMAADAVQIKKNGFEIIKVKVGGSKELDVERIRMIREAAGDSITLRIDANQGWSVETAIETLTLLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADESCCNSFDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQVGGFLESRLGFTAAAHVALVSKTICYYDFDTPLMFEADPVRGGIVYQQRGIIEVPETAGLGAGYQKDYLSGLEKICIN 3tcs A 1.88 BS03 DAL A 1 M119 K145 R147 D183 N185 E235 H285 E311 M119 K145 R147 D183 N185 E235 H285 E311 R18 V31 T33 G75 S76 S117 K145 R147 D157 D183 N185 E209 D230 G234 E235 Q256 D258 H285 A287 N288 K308 E311 I314 G316 R18 V31 T33 G75 S76 S117 K145 R147 D157 D183 N185 E209 D230 G234 E235 Q256 D258 H285 A287 N288 K308 E311 I314 G316 ? 0000287,0016052,0016836,0046872 Q161M1 370 MKLKAIETFTNDAVGFVRVTTQDGAQGWGQVSTYHADITCTVLHRQVAPWMLGQDITDLDDLLDIVTEREHKFPGSYLRRAMAGVDTAIWDLRGKQQGKPVAEVLGGTPGLIRAYASSMKRDITPRDEAERLKRLRDTQGFTAFKVRAGAEVGRNRDEWPGRTEEIIPTMRRELGDDVDLLIDANSCYTPDRAIEVGHMLQDHGFCHFEEPCPYWELAQTKQVTDALDIDVTGGEQDCDLPTWQRMIDMRAVDIVQPDILYLGGICRTLRVVEMARAAGLPVTPHCANWSLVTLFTMHLLRAIPNAGKYLEFSIEGPDYYPWQEGLFVKTPYEIEDGHARVTDAPGWGVEISPEWLARSQYQSSEI 3tcs B 1.88 BS03 DAL B 1 M119 K145 R147 D183 N185 E235 H285 E311 M120 K146 R148 D184 N186 E236 H286 E312 R18 V31 T33 G75 S76 S117 K145 R147 D157 D183 N185 E209 D230 G234 E235 Q256 D258 H285 A287 N288 K308 E311 I314 G316 R19 V32 T34 G76 S77 S118 K146 R148 D158 D184 N186 E210 D231 G235 E236 Q257 D259 H286 A288 N289 K309 E312 I315 G317 ? 0000287,0016052,0016836,0046872 Q161M1 370 SMKLKAIETFTNDAVGFVRVTTQDGAQGWGQVSTYHADITCTVLHRQVAPWMLGQDITDLDDLLDIVTEREHKFPGSYLRRAMAGVDTAIWDLRGKQQGKPVAEVLGGTPGLIRAYASSMKRDITPRDEAERLKRLRDTQGFTAFKVRAGAEVGRNRDEWPGRTEEIIPTMRRELGDDVDLLIDANSCYTPDRAIEVGHMLQDHGFCHFEEPCPYWELAQTKQVTDALDIDVTGGEQDCDLPTWQRMIDMRAVDIVQPDILYLGGICRTLRVVEMARAAGLPVTPHCANWSLVTLFTMHLLRAIPNAGKYLEFSIEGPDYYPWQEGLFVKTPYEIEDGHARVTDAPGWGVEISPEWLARSQYQSSEI 4c5b A 1.5 BS02 DAL A 1 E15 H63 Y216 G276 E15 H63 Y216 G276 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0042803,0046872,0071555 P07862 29208891 311 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5b A 1.5 BS03 DAL A 2 K215 Y216 G276 S281 L282 K215 Y216 G276 S281 L282 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0042803,0046872,0071555 P07862 29208891 312 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5b B 1.5 BS02 DAL B 1 E15 H63 Y216 G276 E15 H63 Y216 G276 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0042803,0046872,0071555 P07862 29208891 311 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5b B 1.5 BS03 DAL B 2 K215 Y216 S281 L282 K215 Y216 S281 L282 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0042803,0046872,0071555 P07862 29208891 312 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5c A 1.4 BS02 DAL A 1 E15 H63 Y216 G276 E15 H63 Y216 G276 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0042803,0046872,0071555 P07862 29208891 311 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5c A 1.4 BS03 DAL A 2 K215 Y216 S281 L282 K215 Y216 S281 L282 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0042803,0046872,0071555 P07862 29208891 312 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5c B 1.4 BS02 DAL B 1 E15 H63 Y216 G276 E15 H63 Y216 G276 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0042803,0046872,0071555 P07862 29208891 311 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5c B 1.4 BS03 DAL B 2 K215 Y216 G276 S281 L282 K215 Y216 G276 S281 L282 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 E15 V18 N21 H63 S150 E213 Y216 R255 D257 E270 N272 G276 H280 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0042803,0046872,0071555 P07862 29208891 312 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4dz1 A 1.9 BS01 DAL A 1 W77 I96 S97 R102 M146 A147 Y148 E191 W53 I72 S73 R78 M122 A123 Y124 E167 0015276,0016020 22418438 301 IVEGRTLNVAVSPASPPMLFKSADGKLQGIDLELFSSYCQSRHCKLNITEYAWDGMLGAVASGQADVAFSGISITDKRKKVIDFSEPYYINSFYLVSMANHKITLNNLNELNKYSIGYPRGMAYSDLIKNDLEPKGYYSLSKVKLYPTYNETMADLKNGNLDLAFIEEPVYFTFKNKKKMPIESRYVFKNVDQLGIAFKKGSPVRDDFNLWLKEQGPQKISGIVDSWMK 4f3s A 2.14 BS01 DAL A 1 W57 I76 S77 R82 M126 A127 Y128 E171 W54 I73 S74 R79 M123 A124 Y125 E168 ? 0006865,0015276,0016020,0016597,0035796,0042597,0042941,0052170 Q8ZPA3 302 SIVEGRTLNVAVSPASPPMLFKSADGKLQGIDLELFSSYCQSRHCKLNITEYAWDGMLGAVASGQADVAFSGISITDKRKKVIDFSEPYYINSFYLVSMANHKITLNNLNELNKYSIGYPRGMAYSDLIKNDLEPKGYYSLSKVKLYPTYNETMADLKNGNLDLAFIEEPVYFTFKNKKKMPIESRYVFKNVDQLGIAFKKGSPVRDDFNLWLKEQGPQKISGIVDSWMKA 4g4x A 1.5 BS01 DAL A 1 Y85 D86 T119 D120 R122 N128 L131 R135 R177 Y9 D10 T43 D44 R46 N52 L55 R59 R101 0009279,0016020 201 AKRVVHFDYDSSDLSTEDYQTLQAHAQFLMANANSKVALTGHTDERGTREYNMALGERRAKAVQNYLITSGVNPQQLEAVSYGKEAPVNPGHDESAWKENRRVEINYE 4g4z A 1.8 BS01 DAL A 1 T236 N237 T270 D271 T273 N279 L282 R286 R329 T17 N18 T51 D52 T54 N60 L63 R67 R110 ? 0016020 Q6RYW5 401 MELTEDLNMELRVFFDTNKSNIKDQYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDASRLSTQGFAWDQPIADNKTKEGRAMNRRVFATITGSR 4g4z B 1.8 BS01 DAL B 1 T236 N237 T270 D271 T273 N279 L282 R286 R329 T18 N19 T52 D53 T55 N61 L64 R68 R111 ? 0016020 Q6RYW5 401 HMELTEDLNMELRVFFDTNKSNIKDQYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDASRLSTQGFAWDQPIADNKTKEGRAMNRRVFATITGSR 4g4z C 1.8 BS01 DAL C 1 T236 N237 T270 D271 T273 N279 L282 R286 R329 T16 N17 T50 D51 T53 N59 L62 R66 R109 ? 0016020 Q6RYW5 401 ELTEDLNMELRVFFDTNKSNIKDQYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDASRLSTQGFAWDQPIADNKTKEGRAMNRRVFATITGSR 4g4z D 1.8 BS01 DAL D 1 T236 N237 T270 D271 T273 N279 L282 R286 R329 T19 N20 T53 D54 T56 N62 L65 R69 R112 ? 0016020 Q6RYW5 401 SHMELTEDLNMELRVFFDTNKSNIKDQYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDASRLSTQGFAWDQPIADNKTKEGRAMNRRVFATITGSR 4g4z E 1.8 BS01 DAL E 1 T236 N237 T270 D271 T273 N279 L282 R286 R329 T18 N19 T52 D53 T55 N61 L64 R68 R111 ? 0016020 Q6RYW5 401 HMELTEDLNMELRVFFDTNKSNIKDQYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDASRLSTQGFAWDQPIADNKTKEGRAMNRRVFATITGSR 4g4z F 1.8 BS01 DAL F 1 T236 N237 T270 D271 T273 N279 L282 R286 R329 T19 N20 T53 D54 T56 N62 L65 R69 R112 ? 0016020 Q6RYW5 401 SHMELTEDLNMELRVFFDTNKSNIKDQYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDASRLSTQGFAWDQPIADNKTKEGRAMNRRVFATITGSR 4g4z G 1.8 BS01 DAL G 1 T236 N237 T270 D271 T273 N279 L282 R286 R329 T19 N20 T53 D54 T56 N62 L65 R69 R112 ? 0016020 Q6RYW5 401 SHMELTEDLNMELRVFFDTNKSNIKDQYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDASRLSTQGFAWDQPIADNKTKEGRAMNRRVFATITGSR 4g4z H 1.8 BS01 DAL H 1 T236 N237 T270 D271 T273 N279 L282 R286 R329 T18 N19 T52 D53 T55 N61 L64 R68 R111 ? 0016020 Q6RYW5 401 HMELTEDLNMELRVFFDTNKSNIKDQYKPEIAKVAEKLSEYPNATARIEGHTDNTGPRKLNERLSLARANSVKSALVNEYNVDASRLSTQGFAWDQPIADNKTKEGRAMNRRVFATITGSR 4mut A 2.25 BS02 DAL A 1 F86 A88 S93 H95 E153 F85 A87 S92 H94 E152 ? 0004180,0006508,0008233,0046872 Q9JN36 24711382 202 NTLQLINKNHPLKKNQEPPHLVLAPFSDHDVYLQPEVAKQWERLVRATGLEKDIRLVSGYRTEKEQRRLWEYSLKENGLAYTKQFVALPGCSEHQIGLAIDVGLKKQEDDDLICPHFRDSAAADLFMQQMMNYGFILRYPEDKQEITGISYEPWHFRYVGLPHSQVITAQKWTLEEYHDYLAQTVRQ 4mut B 2.25 BS02 DAL B 1 F86 A88 S93 H95 E153 F85 A87 S92 H94 E152 ? 0004180,0006508,0008233,0046872 Q9JN36 24711382 202 NTLQLINKNHPLKKNQEPPHLVLAPFSDHDVYLQPEVAKQWERLVRATGLEKDIRLVSGYRTEKEQRRLWEYSLKENGLAYTKQFVALPGCSEHQIGLAIDVGLKKQEDDDLICPHFRDSAAADLFMQQMMNYGFILRYPEDKQEITGISYEPWHFRYVGLPHSQVITAQKWTLEEYHDYLAQTVRQF 4n8g A 1.502 BS01 DAL A 1 E152 M179 N216 Y220 S241 D242 Q243 E125 M152 N189 Y193 S214 D215 Q216 ? 0030288,0055085 Q1QZT7 25540822 402 ATTLNLSYNGPPDTDKNAVHLFASNLKRLVEEKTDGDIQLKLYPNSMLGEEQERMEQVINTPSLNIASFAGLSPIVPEIYVSAIPFLFEDYEAAHQFFDEGDYWNKVEDTLEERTGAELLGVIEEGGFLDFTNSKRPISSPEDFEGLRFRAMDPSQVALYEAFGASGTPIPWTDTYMALKTNVADGQMNPPMYIIMGSLYEVQKYLTLANVQYSDQFLIANGEWYDDLSEENRQAIEAAVQEASELNREDVEKRVDERIQFLADQGMEVIEPTEDELAAFREKGQPAYIEWLTDEQGIDRAWIEMALEDAGQSDLLANAENLYFQ 4n8g A 1.502 BS02 DAL A 2 R177 M179 W199 N216 Y220 R150 M152 W172 N189 Y193 ? 0030288,0055085 Q1QZT7 25540822 403 ATTLNLSYNGPPDTDKNAVHLFASNLKRLVEEKTDGDIQLKLYPNSMLGEEQERMEQVINTPSLNIASFAGLSPIVPEIYVSAIPFLFEDYEAAHQFFDEGDYWNKVEDTLEERTGAELLGVIEEGGFLDFTNSKRPISSPEDFEGLRFRAMDPSQVALYEAFGASGTPIPWTDTYMALKTNVADGQMNPPMYIIMGSLYEVQKYLTLANVQYSDQFLIANGEWYDDLSEENRQAIEAAVQEASELNREDVEKRVDERIQFLADQGMEVIEPTEDELAAFREKGQPAYIEWLTDEQGIDRAWIEMALEDAGQSDLLANAENLYFQ 4n8g B 1.502 BS01 DAL B 1 E152 M179 N216 S241 D242 Q243 E125 M152 N189 S214 D215 Q216 ? 0030288,0055085 Q1QZT7 25540822 402 ATTLNLSYNGPPDTDKNAVHLFASNLKRLVEEKTDGDIQLKLYPNSMLGEEQERMEQVINTPSLNIASFAGLSPIVPEIYVSAIPFLFEDYEAAHQFFDEGDYWNKVEDTLEERTGAELLGVIEEGGFLDFTNSKRPISSPEDFEGLRFRAMDPSQVALYEAFGASGTPIPWTDTYMALKTNVADGQMNPPMYIIMGSLYEVQKYLTLANVQYSDQFLIANGEWYDDLSEENRQAIEAAVQEASELNREDVEKRVDERIQFLADQGMEVIEPTEDELAAFREKGQPAYIEWLTDEQGIDRAWIEMALEDAGQSDLLANAEN 4n8g B 1.502 BS02 DAL B 2 R177 M179 W199 N216 Y220 R150 M152 W172 N189 Y193 ? 0030288,0055085 Q1QZT7 25540822 403 ATTLNLSYNGPPDTDKNAVHLFASNLKRLVEEKTDGDIQLKLYPNSMLGEEQERMEQVINTPSLNIASFAGLSPIVPEIYVSAIPFLFEDYEAAHQFFDEGDYWNKVEDTLEERTGAELLGVIEEGGFLDFTNSKRPISSPEDFEGLRFRAMDPSQVALYEAFGASGTPIPWTDTYMALKTNVADGQMNPPMYIIMGSLYEVQKYLTLANVQYSDQFLIANGEWYDDLSEENRQAIEAAVQEASELNREDVEKRVDERIQFLADQGMEVIEPTEDELAAFREKGQPAYIEWLTDEQGIDRAWIEMALEDAGQSDLLANAEN 4n8g C 1.502 BS01 DAL C 1 E152 M179 N216 Y220 S241 D242 Q243 E125 M152 N189 Y193 S214 D215 Q216 ? 0030288,0055085 Q1QZT7 25540822 402 ATTLNLSYNGPPDTDKNAVHLFASNLKRLVEEKTDGDIQLKLYPNSMLGEEQERMEQVINTPSLNIASFAGLSPIVPEIYVSAIPFLFEDYEAAHQFFDEGDYWNKVEDTLEERTGAELLGVIEEGGFLDFTNSKRPISSPEDFEGLRFRAMDPSQVALYEAFGASGTPIPWTDTYMALKTNVADGQMNPPMYIIMGSLYEVQKYLTLANVQYSDQFLIANGEWYDDLSEENRQAIEAAVQEASELNREDVEKRVDERIQFLADQGMEVIEPTEDELAAFREKGQPAYIEWLTDEQGIDRAWIEMALEDAGQSDLL 4n8g C 1.502 BS02 DAL C 2 R177 M179 W199 N216 Y220 R150 M152 W172 N189 Y193 ? 0030288,0055085 Q1QZT7 25540822 403 ATTLNLSYNGPPDTDKNAVHLFASNLKRLVEEKTDGDIQLKLYPNSMLGEEQERMEQVINTPSLNIASFAGLSPIVPEIYVSAIPFLFEDYEAAHQFFDEGDYWNKVEDTLEERTGAELLGVIEEGGFLDFTNSKRPISSPEDFEGLRFRAMDPSQVALYEAFGASGTPIPWTDTYMALKTNVADGQMNPPMYIIMGSLYEVQKYLTLANVQYSDQFLIANGEWYDDLSEENRQAIEAAVQEASELNREDVEKRVDERIQFLADQGMEVIEPTEDELAAFREKGQPAYIEWLTDEQGIDRAWIEMALEDAGQSDLL 4n8g D 1.502 BS01 DAL D 1 E152 M179 N216 S241 D242 Q243 E125 M152 N189 S214 D215 Q216 ? 0030288,0055085 Q1QZT7 25540822 402 ATTLNLSYNGPPDTDKNAVHLFASNLKRLVEEKTDGDIQLKLYPNSMLGEEQERMEQVINTPSLNIASFAGLSPIVPEIYVSAIPFLFEDYEAAHQFFDEGDYWNKVEDTLEERTGAELLGVIEEGGFLDFTNSKRPISSPEDFEGLRFRAMDPSQVALYEAFGASGTPIPWTDTYMALKTNVADGQMNPPMYIIMGSLYEVQKYLTLANVQYSDQFLIANGEWYDDLSEENRQAIEAAVQEASELNREDVEKRVDERIQFLADQGMEVIEPTEDELAAFREKGQPAYIEWLTDEQGIDRAWIEMALEDAGQ 4n8g D 1.502 BS02 DAL D 2 R177 M179 W199 N216 Y220 R150 M152 W172 N189 Y193 ? 0030288,0055085 Q1QZT7 25540822 403 ATTLNLSYNGPPDTDKNAVHLFASNLKRLVEEKTDGDIQLKLYPNSMLGEEQERMEQVINTPSLNIASFAGLSPIVPEIYVSAIPFLFEDYEAAHQFFDEGDYWNKVEDTLEERTGAELLGVIEEGGFLDFTNSKRPISSPEDFEGLRFRAMDPSQVALYEAFGASGTPIPWTDTYMALKTNVADGQMNPPMYIIMGSLYEVQKYLTLANVQYSDQFLIANGEWYDDLSEENRQAIEAAVQEASELNREDVEKRVDERIQFLADQGMEVIEPTEDELAAFREKGQPAYIEWLTDEQGIDRAWIEMALEDAGQ 4ngu A 2.5 BS01 DAL A 1 E156 M182 N219 S244 Q246 E128 M154 N191 S216 Q218 ? 0030246,0055085 Q311Q1 25540822 402 MAAAMTVKMSYNGPPSLEDNAVHAFATTFKELVEKESGGGIVIDLYPNSQLGNEQQRMEQVMTGPMINVASFGGMETVFPEMFATNVPFMFESYAAAHEFFDNSSFMDKAGKELRSRTGIELLAVVEEGGFIAFTSKKPVRSPADFKGMKFRAMDASQVAMYEAFGASGTPIPWTEVYLALKTGVADGQMNPPTYIIIGSLYEVQDHLTLANVQYSDQFLLINGELLDSLPDSQRQVIRKAAHEANVKTRQFVESQVDERVKFLASKGMTVYTPTAEELAQFKELGSPSYIKWLSGQIDTAWIDHAMEDARKANEAV 4ngu A 2.5 BS02 DAL A 2 R180 M182 W202 N219 Y223 R152 M154 W174 N191 Y195 ? 0030246,0055085 Q311Q1 25540822 403 MAAAMTVKMSYNGPPSLEDNAVHAFATTFKELVEKESGGGIVIDLYPNSQLGNEQQRMEQVMTGPMINVASFGGMETVFPEMFATNVPFMFESYAAAHEFFDNSSFMDKAGKELRSRTGIELLAVVEEGGFIAFTSKKPVRSPADFKGMKFRAMDASQVAMYEAFGASGTPIPWTEVYLALKTGVADGQMNPPTYIIIGSLYEVQDHLTLANVQYSDQFLLINGELLDSLPDSQRQVIRKAAHEANVKTRQFVESQVDERVKFLASKGMTVYTPTAEELAQFKELGSPSYIKWLSGQIDTAWIDHAMEDARKANEAV 4oak A 2.0 BS02 DAL A 1 H95 D102 E153 W155 H156 H95 D102 E153 W155 H156 ? 0004180,0006508,0008233,0046872 -logKd/Ki=4.22, Ki=59.7uM Q9JN36 24711382 202 MNTLQLINKNHPLKKNQEPPHLVLAPFSDHDVYLQPEVAKQWERLVRATGLEKDIRLVSGYRTEKEQRRLWEYSLKENGLAYTKQFVALPGCSEHQIGLAIDVGLKKQEDDDLICPHFRDSAAADLFMQQMMNYGFILRYPEDKQEITGISYEPWHFRYVGLPHSQVITAQKWTLEEYHDYLAQTVRQFA 4oak A 2.0 BS03 DAL A 2 F86 A88 S93 F86 A88 S93 ? 0004180,0006508,0008233,0046872 -logKd/Ki=4.22, Ki=59.7uM Q9JN36 24711382 203 MNTLQLINKNHPLKKNQEPPHLVLAPFSDHDVYLQPEVAKQWERLVRATGLEKDIRLVSGYRTEKEQRRLWEYSLKENGLAYTKQFVALPGCSEHQIGLAIDVGLKKQEDDDLICPHFRDSAAADLFMQQMMNYGFILRYPEDKQEITGISYEPWHFRYVGLPHSQVITAQKWTLEEYHDYLAQTVRQFA 4oak B 2.0 BS02 DAL B 1 F86 H95 D102 I114 H156 F86 H95 D102 I114 H156 ? 0004180,0006508,0008233,0046872 -logKd/Ki=4.22, Ki=59.7uM Q9JN36 24711382 202 MNTLQLINKNHPLKKNQEPPHLVLAPFSDHDVYLQPEVAKQWERLVRATGLEKDIRLVSGYRTEKEQRRLWEYSLKENGLAYTKQFVALPGCSEHQIGLAIDVGLKKQEDDDLICPHFRDSAAADLFMQQMMNYGFILRYPEDKQEITGISYEPWHFRYVGLPHSQVITAQKWTLEEYHDYLAQTVRQFA 4oak B 2.0 BS03 DAL B 2 R62 F86 A88 S93 H95 Y140 R62 F86 A88 S93 H95 Y140 ? 0004180,0006508,0008233,0046872 -logKd/Ki=4.22, Ki=59.7uM Q9JN36 24711382 203 MNTLQLINKNHPLKKNQEPPHLVLAPFSDHDVYLQPEVAKQWERLVRATGLEKDIRLVSGYRTEKEQRRLWEYSLKENGLAYTKQFVALPGCSEHQIGLAIDVGLKKQEDDDLICPHFRDSAAADLFMQQMMNYGFILRYPEDKQEITGISYEPWHFRYVGLPHSQVITAQKWTLEEYHDYLAQTVRQFA 4ox5 A 1.8 BS03 DAL A 1 A146 S151 Y201 E204 A93 S98 Y148 E151 ? 0006508,0008233 Q8DQQ1 24909784 307 GSHMEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLIKAMQEAGFPISDHYSGFRSYETQTKLYQDYVNGKEAADRYSARPGYSEHQTGLAFDVIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEIAESGLSLEEYYGFEGGDYV 4y4v A 2.04 BS01 DAL A 1 K107 E110 G111 G154 H155 K93 E96 G97 G140 H141 ? 0008360,0009252,0016740,0071555 Kd=224uM -logKd/Ki=3.65, Kd=224uM O25255 26306031 401 LNASDRLLEIMRLYQKQGLEMVGQKLDSYLADKSFWAEELQNKDTDFGYYQNKQFLFVANKSKPSLEFYEIENNMLKKINSSKALVGSKKGDKTLEGDLATPIGVYRITQKLERLDQYYGVLAFVTNYPNLYDTLKKRTGHGIWVHGMPLNGDRNELNTKGCIAIENPLLSSYDKVLKGEKAFLITYEDKFFPSTKEELSMILSSLFQWKEAWARGDFERYMRFYNPNFTRYDGMKFNAFKEYKKRVFAKNEKKNIAFSSINVIPYPNSQNKRLFYVVFDQDYKAYQHNKLSYSSNSQKELYIEIENNQVSIIMEK 4y4v A 2.04 BS02 DAL A 2 Y133 G156 W158 C176 Y119 G142 W144 C162 ? 0008360,0009252,0016740,0071555 Kd=224uM -logKd/Ki=3.65, Kd=224uM O25255 26306031 402 LNASDRLLEIMRLYQKQGLEMVGQKLDSYLADKSFWAEELQNKDTDFGYYQNKQFLFVANKSKPSLEFYEIENNMLKKINSSKALVGSKKGDKTLEGDLATPIGVYRITQKLERLDQYYGVLAFVTNYPNLYDTLKKRTGHGIWVHGMPLNGDRNELNTKGCIAIENPLLSSYDKVLKGEKAFLITYEDKFFPSTKEELSMILSSLFQWKEAWARGDFERYMRFYNPNFTRYDGMKFNAFKEYKKRVFAKNEKKNIAFSSINVIPYPNSQNKRLFYVVFDQDYKAYQHNKLSYSSNSQKELYIEIENNQVSIIMEK 4y4v B 2.04 BS01 DAL B 1 K107 E110 G111 G154 H155 K93 E96 G97 G140 H141 ? 0008360,0009252,0016740,0071555 Kd=224uM O25255 26306031 402 LNASDRLLEIMRLYQKQGLEMVGQKLDSYLADKSFWAEELQNKDTDFGYYQNKQFLFVANKSKPSLEFYEIENNMLKKINSSKALVGSKKGDKTLEGDLATPIGVYRITQKLERLDQYYGVLAFVTNYPNLYDTLKKRTGHGIWVHGMPLNGDRNELNTKGCIAIENPLLSSYDKVLKGEKAFLITYEDKFFPSTKEELSMILSSLFQWKEAWARGDFERYMRFYNPNFTRYDGMKFNAFKEYKKRVFAKNEKKNIAFSSINVIPYPNSQNKRLFYVVFDQDYKAYQHNKLSYSSNSQKELYIEIENNQVSIIMEK 5c1p D 2.4 BS02 DAL D 1 Y216 R255 N272 P275 G276 Y212 R251 N268 P271 G272 E15 V18 L21 H63 D213 Y216 R255 D257 E270 N272 G276 H280 E14 V17 L20 H62 D209 Y212 R251 D253 E266 N268 G272 H276 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q8ZIE7 26894530 402 AEKVAVLLGGTSAEREVSLLSGQAVLAGLKEAGIDAYGVDTKDFPVTQLKEQGFDKVFIALHGRGGEDGTLQGVLEFLQLPYTGSGVMASALTMDKLRTKLVWQALGLPISPYVALNRQQFETLSPEELVACVAKLGLPLIVKPSHEVGMSKVDHASELQKALVEAFQHDSDVLIEKWLSGPEFTVAILGDEVLPSIRIQPPGVFYDYDAKYLSDKTQYFCPSGLSDESEQQLAALALQAYHALDCSGWGRVDVMQDRDGHFYLLEVNTSPGMTSHSLVPMAARQYGLSFSQLVARILMLAD 5c1p D 2.4 BS03 DAL D 2 K215 Y216 S281 L282 K211 Y212 S277 L278 E15 V18 L21 H63 D213 Y216 R255 D257 E270 N272 G276 H280 E14 V17 L20 H62 D209 Y212 R251 D253 E266 N268 G272 H276 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q8ZIE7 26894530 403 AEKVAVLLGGTSAEREVSLLSGQAVLAGLKEAGIDAYGVDTKDFPVTQLKEQGFDKVFIALHGRGGEDGTLQGVLEFLQLPYTGSGVMASALTMDKLRTKLVWQALGLPISPYVALNRQQFETLSPEELVACVAKLGLPLIVKPSHEVGMSKVDHASELQKALVEAFQHDSDVLIEKWLSGPEFTVAILGDEVLPSIRIQPPGVFYDYDAKYLSDKTQYFCPSGLSDESEQQLAALALQAYHALDCSGWGRVDVMQDRDGHFYLLEVNTSPGMTSHSLVPMAARQYGLSFSQLVARILMLAD 5nri A 1.5 BS02 DAL A 1 R260 S286 L287 R259 S285 L286 V25 N28 H70 H218 R260 G281 H285 V24 N27 H69 H217 R259 G280 H284 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 A3NZL3 31260169 402 SGIDPKRFGKVAVLLGGDSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDYAARAQDIVAKLGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSIEGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIARRAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGIGYSELVVKVLSLTLD 5nri A 1.5 BS03 DAL A 2 R260 N277 R259 N276 V25 N28 H70 H218 R260 G281 H285 V24 N27 H69 H217 R259 G280 H284 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 A3NZL3 31260169 403 SGIDPKRFGKVAVLLGGDSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDYAARAQDIVAKLGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSIEGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIARRAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGIGYSELVVKVLSLTLD 5zhw A 2.18 BS02 DAL A 1 W179 S186 H188 E238 W92 S99 H101 E151 3.4.17.- 0006508,0008233 Q47746 30016658 302 EWSLILVNRQNPIPAQYDVELEQLSNGERIDIRISPYLQDLFDAARADGVYPIVASGYRTTEKQQEIMDEKVAEYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYRFGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATKIYHQGLCLEEYLNTEK 5zhw A 2.18 BS03 DAL A 2 D195 E238 D108 E151 3.4.17.- 0006508,0008233 Q47746 30016658 303 EWSLILVNRQNPIPAQYDVELEQLSNGERIDIRISPYLQDLFDAARADGVYPIVASGYRTTEKQQEIMDEKVAEYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYRFGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATKIYHQGLCLEEYLNTEK 5zhw B 2.18 BS02 DAL B 1 W179 A181 S186 H188 W92 A94 S99 H101 3.4.17.- 0006508,0008233 Q47746 30016658 302 EWSLILVNRQNPIPAQYDVELEQLSNGERIDIRISPYLQDLFDAARADGVYPIVASGYRTTEKQQEIMDEKVAEYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYRFGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATKIYHQGLCLEEYLNTEK 5zhw B 2.18 BS03 DAL B 2 R146 D195 R59 D108 3.4.17.- 0006508,0008233 Q47746 30016658 303 EWSLILVNRQNPIPAQYDVELEQLSNGERIDIRISPYLQDLFDAARADGVYPIVASGYRTTEKQQEIMDEKVAEYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYRFGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATKIYHQGLCLEEYLNTEK 6a6a A 2.26 BS01 DAL A 1 W179 A181 S186 Y225 W92 A94 S99 Y138 3.4.17.- 0006508,0008233 Q47746 30016658 301 EWSLILVNRQNPIPAQYDVELEQLSNGERIDIRISPYLQDLFDAARADGVYPIVASGYRTTEKQQEIMDEKVAEYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYRFGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATKIYHQGLCLEEYLNTEKLE 6a6a B 2.26 BS01 DAL B 1 Q151 W179 V180 A181 S186 Y225 E238 Q64 W92 V93 A94 S99 Y138 E151 3.4.17.- 0006508,0008233 Q47746 30016658 301 EWSLILVNRQNPIPAQYDVELEQLSNGERIDIRISPYLQDLFDAARADGVYPIVASGYRTTEKQQEIMDEKVAEYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYRFGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATKIYHQGLCLEEYLNTEK 6csf M 3.3 BS02 DAL M 1 T75 G77 G79 N80 Q170 F273 S274 T58 G60 G62 N63 Q150 F253 S254 ? 0003333,0005283,0005886,0006814,0006865,0015293,0016020,0035725,0055085 -logKd/Ki=5.44, Kd=3.6uM Q6LX42 30659158 502 WGPYMLVLLLGTGIFLTLRLGFMQIHTLPYALKLAFSKETSEGDISHFQALMTALAATIGTGNIAGVATAYVLGGPGAIFWMWVTAFFGMATKYAEAVLAIKYRTVDDNGEMAGGPMYFLEKGLPLGKILGVAFAFFGAFAAFGIGNMVQTNSVADAVASNFGVDPLITGFVLAIFTAAVILGGIKSIGKATGIIVPFMAVFYILAGLVILAMNIGYIIPAFGTIFSSAFNFSAGFGALIGTAIMWGVKRGVFSNEAGLGSAPIAAAAAKTDHPGRQALVSMTGTFLDTIVVCTITGLVLTIAGLKAFPGLTDLTGASLTAASFDALMPMGGLIVTIGLVFFAYSTVLGWSYYGEKCFEYLIGTKGIRLYRIAFVLVAFWGATASLPLVWNIADTLNGAMAIPNLIGLLLLSGVVVSETKAFNEIRKNEAK 6g7n A 1.1 BS01 DAL A 1 Y14 Y144 Y200 N271 Y11 Y141 Y197 N268 ? 0006826,0030288,0046872 Q10Z45 30217820 401 GAINLYSSRHYDTDQALYDSFTKKTGLKVNLIEGKGDKLIERIKSEGANSPADVFMTVDAGRLWRAQEAGILQPISSSTLNNKIPANLRSPEKLWFGFSKRARVIMYNKNKVQPSELSTYEDLAQNKWKGKIVIRSSSNIYNQSLIASLIEIHGMSDAEGWAKGFVRNFARPPEGNDTAQIKAVAAGIGDIGLANSYYLARLKRSSKPEDQAVADKVGMFFPNQNGRGTHVNISGGGVVKNAPNKEGAIKFLEYLVSPEAQKIFSEGNNEYPVVAGVPIASVLKPFGSFKNDSTNVSVYGKLNADAIKLMDRVGWKLE 6g7n B 1.1 BS01 DAL B 1 Y14 R104 Y144 Y200 N271 Y11 R101 Y141 Y197 N268 ? 0006826,0030288,0046872 Q10Z45 30217820 401 GAINLYSSRHYDTDQALYDSFTKKTGLKVNLIEGKGDKLIERIKSEGANSPADVFMTVDAGRLWRAQEAGILQPISSSTLNNKIPANLRSPEKLWFGFSKRARVIMYNKNKVQPSELSTYEDLAQNKWKGKIVIRSSSNIYNQSLIASLIEIHGMSDAEGWAKGFVRNFARPPEGNDTAQIKAVAAGIGDIGLANSYYLARLKRSSKPEDQAVADKVGMFFPNQNGRGTHVNISGGGVVKNAPNKEGAIKFLEYLVSPEAQKIFSEGNNEYPVVAGVPIASVLKPFGSFKNDSTNVSVYGKLNADAIKLMDRVGWKLE 6ll9 B 2.7 BS01 DAL B 1 G299 S304 G238 S243 V19 R22 H82 R278 G299 I303 V17 R20 H80 R217 G238 I242 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 A0KKW8 32609505 400 NIHVLLLCGGGGSEHEVSLRSANFLEQQLGLLPGVDVTRVEMFADRWLSADGRECKLGLDKLLSFDSVARPVDYVVPCIHGYPGETGDLQSFLELAGLPYLGCDAEASKICFNKISTKLWLSAIGIPNTPYLFLTEQNDAALSEAKAALVKGIADAFKAVPRELEVAVYQYGDELVATYPGEICALRAEGLTQAQADAIHEYALKAFRQLKLTHLSRIDFFLTEEGEILLNEINTFPGMTSISMFPKLLEHHGHRFVDYLEQILRK 6u1d A 1.9 BS01 DAL A 1 E13 H82 Y229 R268 E15 H84 Y231 R270 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHH 6u1d A 1.9 BS02 DAL A 2 K228 R268 G288 S293 K230 R270 G290 S295 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHH 6u1d B 1.9 BS01 DAL B 1 E13 H82 Y229 R268 G288 E15 H84 Y231 R270 G290 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHHH 6u1d B 1.9 BS02 DAL B 2 K228 Y229 R268 G288 S293 K230 Y231 R270 G290 S295 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHHH 6u1e A 2.1 BS01 DAL A 1 E13 H82 Y229 R268 G288 E14 H83 Y230 R269 G289 V16 L19 H82 E226 R268 G288 T292 V17 L20 H83 E227 R269 G289 T293 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 EMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHH 6u1e A 2.1 BS02 DAL A 2 K228 R268 G288 S293 K229 R269 G289 S294 V16 L19 H82 E226 R268 G288 T292 V17 L20 H83 E227 R269 G289 T293 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 EMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHH 6u1e B 2.1 BS01 DAL B 1 E13 H82 Y229 R268 G288 E15 H84 Y231 R270 G290 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHHH 6u1e B 2.1 BS02 DAL B 2 K228 R268 G288 S293 K230 R270 G290 S295 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHHH 6u1f A 2.3 BS01 DAL A 1 E13 H82 Y229 R268 G288 E15 H84 Y231 R270 G290 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHH 6u1f A 2.3 BS02 DAL A 2 K228 R268 G288 S293 K230 R270 G290 S295 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHH 6u1f B 2.3 BS01 DAL B 1 E13 H82 Y229 R268 G288 E15 H84 Y231 R270 G290 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHH 6u1f B 2.3 BS02 DAL B 2 K228 R268 G288 S293 K230 R270 G290 S295 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHH 6u1g A 2.4 BS01 DAL A 1 E13 H82 Y229 R268 E15 H84 Y231 R270 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHHH 6u1g A 2.4 BS02 DAL A 2 K228 R268 G288 S293 K230 R270 G290 S295 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHHH 6u1g B 2.4 BS01 DAL B 1 E13 H82 R268 G288 E15 H84 R270 G290 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHH 6u1g B 2.4 BS02 DAL B 2 K228 R268 G288 S293 K230 R270 G290 S295 V16 L19 H82 E226 R268 G288 T292 V18 L21 H84 E228 R270 G290 T294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MEMRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHH 6u1j A 2.2 BS01 DAL A 1 E13 H82 Y229 R268 E13 H82 Y229 R268 V16 L19 H82 E226 R268 G288 T292 V16 L19 H82 E226 R268 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHHH 6u1j A 2.2 BS02 DAL A 2 R268 G288 S293 R268 G288 S293 V16 L19 H82 E226 R268 G288 T292 V16 L19 H82 E226 R268 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHHH 6u1j C 2.2 BS01 DAL C 1 E13 H82 Y229 G288 E13 H82 Y229 G288 V16 L19 H82 E226 R268 G288 T292 V16 L19 H82 E226 R268 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHHH 6u1j C 2.2 BS02 DAL C 2 K228 R268 G288 S293 K228 R268 G288 S293 V16 L19 H82 E226 R268 G288 T292 V16 L19 H82 E226 R268 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHHH 6u1k A 1.67 BS01 DAL A 1 E13 H82 Y229 R268 G288 E13 H82 Y229 R268 G288 V16 L19 H82 E226 R268 G288 T292 V16 L19 H82 E226 R268 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHHH 6u1k A 1.67 BS02 DAL A 2 K228 R268 G288 S293 K228 R268 G288 S293 V16 L19 H82 E226 R268 G288 T292 V16 L19 H82 E226 R268 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHHH 6u1k B 1.67 BS01 DAL B 1 E13 H82 Y229 R268 G288 E13 H82 Y229 R268 G288 V16 L19 H82 E226 R268 G288 T292 V16 L19 H82 E226 R268 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHH 6u1k B 1.67 BS02 DAL B 2 K228 R268 G288 S293 K228 R268 G288 S293 V16 L19 H82 E226 R268 G288 T292 V16 L19 H82 E226 R268 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHH 6u1k C 1.67 BS01 DAL C 1 E13 H82 Y229 R268 E13 H82 Y229 R268 V16 L19 H82 E226 R268 G288 T292 V16 L19 H82 E226 R268 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHH 6u1k C 1.67 BS02 DAL C 2 K228 Y229 R268 G288 S293 K228 Y229 R268 G288 S293 V16 L19 H82 E226 R268 G288 T292 V16 L19 H82 E226 R268 G288 T292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHHHH 6u1k D 1.67 BS01 DAL D 1 E13 H82 Y229 R268 G288 E13 H82 Y228 R267 G287 V16 L19 H82 E226 R268 G288 T292 V16 L19 H82 E225 R267 G287 T291 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 401 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHH 6u1k D 1.67 BS02 DAL D 2 K228 R268 G288 S293 K227 R267 G287 S292 V16 L19 H82 E226 R268 G288 T292 V16 L19 H82 E225 R267 G287 T291 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q5SHZ3 32335509 402 MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALTHH 6u83 A 2.3566 BS01 DAL A 1 Y285 D286 A319 S320 N332 L335 R339 Q379 Y46 D47 A80 S81 N93 L96 R100 Q140 ? 0016020 Q5NH85 403 IDESKYVLPAGIKQCEGNFNLTEDGVACYTINGDDVTVYLDTKFAYDKATLNAKGKKAIASFVNFIKDSNISSVTVKGYASQGQTGSEFDIYNQKLSEKRAQAVADYMKQLGLDSEKIITKGFGYNDTLGGIHKSDPRNQRVEASVSAPLKEAN 7r27 A 2.01 BS01 DAL A 1 D198 C270 G271 G296 T298 V302 D191 C263 G264 G289 T291 V295 0005524,0047473,0070395 35907949 701 KNIITTIDDYARTQPNNVVYDVQGVTHTYAELKAYSDALAAHLDTLDLPAKDPIIVFGGQTFEMIATFLGVVKSGRAYIPIDTHSPNERLTMINEIAKPAAVIAVADLPTGVGTTPVITPDQLAAIFATPVDYQADHVVSGDDNYYIIFTMPKGVQISHDNLVSYVDWMLSDDFGLPDQPNSLSQPPYSFDLSVMDVYPTLALGGTLYALPKAVTDDFKQLFAALPTLPINVWVSTPSFMDICLLEPKFNAENLPTLTHFLFCGEELTHKTAATLKKRFPDARIFNTYGPTETCVAVTQIEITDAALAQYDRLPIGYAKADTRILVVDENGEAVPNGTEGELIIAGPSVSKGYLNNPEKTAKAFFELDGQPAYHSGDIGTMDADGLFRYRGRVD 7r27 B 2.01 BS01 DAL B 1 D198 C270 G296 T298 V302 D196 C268 G294 T296 V300 0005524,0047473,0070395 35907949 701 KNIITTIDDYARTQPNNVVYDVQGVTHTYAELKAYSDALAAHLDTLDLPAKDPIIVFGGQTFEMIATFLGVVKSGRAYIPIDTHSPNERLTMINEIAKPAAVIAVADLPTGVGTTPVITPDQLAAIFATPVDYQADHVVSGDDNYYIIFTSGTTGMPKGVQISHDNLVSYVDWMLSDDFGLPDQPNSLSQPPYSFDLSVMDVYPTLALGGTLYALPKAVTDDFKQLFAALPTLPINVWVSTPSFMDICLLEPKFNAENLPTLTHFLFCGEELTHKTAATLKKRFPDARIFNTYGPTETCVAVTQIEITDAALAQYDRLPIGYAKADTRILVVDENGEAVPNGTEGELIIAGPSVSKGYLNNPEKTAKAFFELDGQPAYHSGDIGTMDADGLFRYRGRV 7rjj A 1.88 BS01 DAL A 1 T441 G442 T475 D476 V478 N484 L487 R491 R534 T14 G15 T48 D49 V51 N57 L60 R64 R107 ? A0A422WJQ0 36695589 601 PDVIRLDSMSLFDTGKWVLKPGSTKRLVSSLMDIKARPGWLIVVAGHTDSVGEEKANQLLSLKRAESVRDWMRDTGDVPDSCFAVQGYGESRPIATNDTPEGRALNRRVEISLVPQVDAC 7rjj B 1.88 BS01 DAL B 1 T441 G442 T475 D476 V478 N484 L487 R491 R534 T14 G15 T48 D49 V51 N57 L60 R64 R107 ? A0A422WJQ0 36695589 601 PDVIRLDSMSLFDTGKWVLKPGSTKRLVSSLMDIKARPGWLIVVAGHTDSVGEEKANQLLSLKRAESVRDWMRDTGDVPDSCFAVQGYGESRPIATNDTPEGRALNRRVEISLVPQVDAC 7uo3 A 1.8 BS02 DAL A 1 D40 R115 D40 R115 ? H9L4J5 36183829 901 MMAVRLTFDGQKLTWPGIGIFKATTGLPDLQWPDKQCVPDAAIPEGNYKLFIQFQGEAPIRNAADCDLGPSWGWSTIPRGQAAGTCEIYWANWGYNRIRLESADEKTRKACGGKRGGFYIHDSTKGYSHGCIEVEPVFFRILKQETEKENGEKTFTVNVKYVSGQQTNGGTKQG 7uo3 A 1.8 BS03 DAL A 2 P136 V137 R140 P136 V137 R140 ? H9L4J5 36183829 902 MMAVRLTFDGQKLTWPGIGIFKATTGLPDLQWPDKQCVPDAAIPEGNYKLFIQFQGEAPIRNAADCDLGPSWGWSTIPRGQAAGTCEIYWANWGYNRIRLESADEKTRKACGGKRGGFYIHDSTKGYSHGCIEVEPVFFRILKQETEKENGEKTFTVNVKYVSGQQTNGGTKQG 8evw A 1.22 BS02 DAL A 1 E18 H100 Y245 G305 E14 H83 Y228 G288 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q9HWI0 37581574 602 KLKVAVLFGGSSEERDVSIASGAQVIQALRSAGHQVLAVDTASGLLGAEEERRLLASKVKEVPPDSDSLAIIRGVDVFFLALHGGTGEDGTLQALLDAGGFAYTGSGHLASAMAMDKDVAKRLFLAAGVETASWLMAPASEEEVREQLGFPLVVKPNSQGSTVGLSIVHSQAELQPAIELAGRYGDEVMLERFVAGREVTVGVLDDQALPVGEILLGGQEVFDYEHKYQAGAVREVFPADLPPAIAAEAQRLALKVHRALKLSGYSRTDFRLDEQGRLWCLEVNTLPGMTATSLLPQAAAAAGIGFAELCERICRLGIERC 8evw A 1.22 BS03 DAL A 2 K244 Y245 G305 S310 L311 K227 Y228 G288 S293 L294 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q9HWI0 37581574 603 KLKVAVLFGGSSEERDVSIASGAQVIQALRSAGHQVLAVDTASGLLGAEEERRLLASKVKEVPPDSDSLAIIRGVDVFFLALHGGTGEDGTLQALLDAGGFAYTGSGHLASAMAMDKDVAKRLFLAAGVETASWLMAPASEEEVREQLGFPLVVKPNSQGSTVGLSIVHSQAELQPAIELAGRYGDEVMLERFVAGREVTVGVLDDQALPVGEILLGGQEVFDYEHKYQAGAVREVFPADLPPAIAAEAQRLALKVHRALKLSGYSRTDFRLDEQGRLWCLEVNTLPGMTATSLLPQAAAAAGIGFAELCERICRLGIERC 8evw B 1.22 BS02 DAL B 1 E18 H100 Y245 R284 G305 E14 H88 Y233 R272 G293 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q9HWI0 37581574 602 KLKVAVLFGGSSEERDVSIASGAQVIQALRSAGHQVLAVDTASGLLGAEEERRLLASKVKEVPPDSDSLAILSAGELAGVDVFFLALHGGTGEDGTLQALLDAGGFAYTGSGHLASAMAMDKDVAKRLFLAAGVETASWLMAPASEEEVREQLGFPLVVKPNSQGSTVGLSIVHSQAELQPAIELAGRYGDEVMLERFVAGREVTVGVLDDQALPVGEILLGGQEVFDYEHKYQAGAVREVFPADLPPAIAAEAQRLALKVHRALKLSGYSRTDFRLDEQGRLWCLEVNTLPGMTATSLLPQAAAAAGIGFAELCERICRLGIERC 8evw B 1.22 BS03 DAL B 2 K244 Y245 G305 S310 L311 K232 Y233 G293 S298 L299 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q9HWI0 37581574 603 KLKVAVLFGGSSEERDVSIASGAQVIQALRSAGHQVLAVDTASGLLGAEEERRLLASKVKEVPPDSDSLAILSAGELAGVDVFFLALHGGTGEDGTLQALLDAGGFAYTGSGHLASAMAMDKDVAKRLFLAAGVETASWLMAPASEEEVREQLGFPLVVKPNSQGSTVGLSIVHSQAELQPAIELAGRYGDEVMLERFVAGREVTVGVLDDQALPVGEILLGGQEVFDYEHKYQAGAVREVFPADLPPAIAAEAQRLALKVHRALKLSGYSRTDFRLDEQGRLWCLEVNTLPGMTATSLLPQAAAAAGIGFAELCERICRLGIERC 8evy A 2.35 BS01 DAL A 1 E31 H79 Y225 R264 E29 H77 Y223 R262 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q9LCT6 37581574 401 LCLDSLLNGTQDPKAFGRVAVLFGGKSAEREVSLKSGAMVLQSLLAAGVDAFGIDVGEDLLQRLVEEKIDRAFIILHGRGGEDGSMQGLLECAGIPYTGSGVLASALAMDKLRTKRVWLSLGLPTPDYAVLASEDDCREAAQRLGFPLIVKPAHEGSSIGMAKVGGLDELIAAWREAARYDSQVLVEQWISGPEFTVATLRGQVLPAIRLGTPHTFYDYDAKYLASDTRYQVPCGLDEAKERELKELTARACDALGIQGWGRADVMQDAEGRFWLLEVNTAPGMTDHSLVPMAARAAGLDFQQLVLAILADSREARG 8evy A 2.35 BS02 DAL A 2 K224 S290 L291 K222 S288 L289 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q9LCT6 37581574 402 LCLDSLLNGTQDPKAFGRVAVLFGGKSAEREVSLKSGAMVLQSLLAAGVDAFGIDVGEDLLQRLVEEKIDRAFIILHGRGGEDGSMQGLLECAGIPYTGSGVLASALAMDKLRTKRVWLSLGLPTPDYAVLASEDDCREAAQRLGFPLIVKPAHEGSSIGMAKVGGLDELIAAWREAARYDSQVLVEQWISGPEFTVATLRGQVLPAIRLGTPHTFYDYDAKYLASDTRYQVPCGLDEAKERELKELTARACDALGIQGWGRADVMQDAEGRFWLLEVNTAPGMTDHSLVPMAARAAGLDFQQLVLAILADSREARG 8evy B 2.35 BS01 DAL B 1 E31 H79 S159 Y225 E29 H77 S157 Y223 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q9LCT6 37581574 401 LCLDSLLNGTQDPKAFGRVAVLFGGKSAEREVSLKSGAMVLQSLLAAGVDAFGIDVGEDLLQRLVEEKIDRAFIILHGRGGEDGSMQGLLECAGIPYTGSGVLASALAMDKLRTKRVWLSLGLPTPDYAVLASEDDCREAAQRLGFPLIVKPAHEGSSIGMAKVGGLDELIAAWREAARYDSQVLVEQWISGPEFTVATLRGQVLPAIRLGTPHTFYDYDAKYLASDTRYQVPCGLDEAKERELKELTARACDALGIQGWGRADVMQDAEGRFWLLEVNTAPGMTDHSLVPMAARAAGLDFQQLVLAILADSREARG 8evy B 2.35 BS02 DAL B 2 S290 L291 S288 L289 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q9LCT6 37581574 402 LCLDSLLNGTQDPKAFGRVAVLFGGKSAEREVSLKSGAMVLQSLLAAGVDAFGIDVGEDLLQRLVEEKIDRAFIILHGRGGEDGSMQGLLECAGIPYTGSGVLASALAMDKLRTKRVWLSLGLPTPDYAVLASEDDCREAAQRLGFPLIVKPAHEGSSIGMAKVGGLDELIAAWREAARYDSQVLVEQWISGPEFTVATLRGQVLPAIRLGTPHTFYDYDAKYLASDTRYQVPCGLDEAKERELKELTARACDALGIQGWGRADVMQDAEGRFWLLEVNTAPGMTDHSLVPMAARAAGLDFQQLVLAILADSREARG 8evy C 2.35 BS01 DAL C 1 E31 H79 Y225 R264 G285 E29 H77 Y223 R262 G283 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q9LCT6 37581574 401 LCLDSLLNGTQDPKAFGRVAVLFGGKSAEREVSLKSGAMVLQSLLAAGVDAFGIDVGEDLLQRLVEEKIDRAFIILHGRGGEDGSMQGLLECAGIPYTGSGVLASALAMDKLRTKRVWLSLGLPTPDYAVLASEDDCREAAQRLGFPLIVKPAHEGSSIGMAKVGGLDELIAAWREAARYDSQVLVEQWISGPEFTVATLRGQVLPAIRLGTPHTFYDYDAKYLASDTRYQVPCGLDEAKERELKELTARACDALGIQGWGRADVMQDAEGRFWLLEVNTAPGMTDHSLVPMAARAAGLDFQQLVLAILADSRE 8evy C 2.35 BS02 DAL C 2 K224 Y225 R264 S290 L291 K222 Y223 R262 S288 L289 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q9LCT6 37581574 402 LCLDSLLNGTQDPKAFGRVAVLFGGKSAEREVSLKSGAMVLQSLLAAGVDAFGIDVGEDLLQRLVEEKIDRAFIILHGRGGEDGSMQGLLECAGIPYTGSGVLASALAMDKLRTKRVWLSLGLPTPDYAVLASEDDCREAAQRLGFPLIVKPAHEGSSIGMAKVGGLDELIAAWREAARYDSQVLVEQWISGPEFTVATLRGQVLPAIRLGTPHTFYDYDAKYLASDTRYQVPCGLDEAKERELKELTARACDALGIQGWGRADVMQDAEGRFWLLEVNTAPGMTDHSLVPMAARAAGLDFQQLVLAILADSRE