3eks A 1.8 BS03 CY9 A 1 Y133 A135 I136 Y143 Y169 A170 P172 M355 F375 Y132 A134 I135 Y142 Y168 A169 P171 M354 F374 3.6.4.- 0000281,0005515,0005524,0005737,0005856,0006338,0007291,0016787,0030723,0031011,0032507,0035060,0035148 -logKd/Ki=5.70, Kd=2uM P10987 18938176 903 DEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTEEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELKDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 3eku A 2.5 BS03 CY9 A 1 A135 I136 V139 Y143 G168 Y169 A170 P172 M355 F375 A122 I123 V126 Y130 G155 Y156 A157 P159 M342 F362 3.6.4.- 0000281,0005515,0005524,0005737,0005856,0006338,0007291,0016787,0030723,0031011,0032507,0035060,0035148 P10987 18938176 903 EVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTEEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELKDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF