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BioLiP
Download all results in tab-seperated text for 30 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1j3j:A (2.3) BS01 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... P13922 12704428 MOAD: Ki=9.8nM
    BindingDB: Ki=0.6nM, IC50=30900nM
    2 1j3j:B (2.3) BS01 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... P13922 12704428 MOAD: Ki=9.8nM
    BindingDB: Ki=0.6nM, IC50=30900nM
    3 2bl9:A (1.9) BS02 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... O02604 16135570 MOAD: Ki=0.16nM
    BindingDB: IC50=180nM, Ki=0.21nM
    4 2bla:A (2.5) BS02 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... O02604 16135570 MOAD: Ki=50nM
    BindingDB: IC50=180nM, Ki=0.21nM
    5 3lmy:A (2.8) BS01 CP6 3.2.1.52 GO:0004553 ... P07686 N/A BindingDB: IC50=9100nM
    6 3lmy:B (2.8) BS01 CP6 3.2.1.52 GO:0004553 ... P07686 N/A BindingDB: IC50=9100nM
    7 3qfx:A (2.2) BS02 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... Q27783 21650210 MOAD: Ki=24.2nM
    8 3qfx:B (2.2) BS02 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... Q27783 21650210 MOAD: Ki=24.2nM
    9 3qg2:A (2.3) BS01 CP6 1.5.1.3
    2.1.1.45    		 GO:0000166 ... D9N170 21650210
    10 3qg2:B (2.3) BS02 CP6 1.5.1.3
    2.1.1.45    		 GO:0000166 ... D9N170 21650210
    11 3qgt:A (2.3) BS01 CP6 1.5.1.3
    2.1.1.45    		 GO:0000166 ... A7UD81 21650210
    12 3qgt:B (2.3) BS02 CP6 1.5.1.3
    2.1.1.45    		 GO:0000166 ... A7UD81 21650210
    13 3um5:A (2.4) BS01 CP6 1.5.1.3
    2.1.1.45    		 GO:0000166 ... A7UD81 22526319 MOAD: Ki=0.6nM
    14 3um5:B (2.4) BS02 CP6 1.5.1.3
    2.1.1.45    		 GO:0000166 ... A7UD81 22526319 MOAD: Ki=0.6nM
    15 4km0:A (1.3) BS01 CP6 1.5.1.3 GO:0004146 ... P9WNX1 24210757 MOAD: Kd=0.91uM
    PDBbind: -logKd/Ki=6.04, Kd=0.91uM
    16 4km0:B (1.3) BS01 CP6 1.5.1.3 GO:0004146 ... P9WNX1 24210757 MOAD: Kd=0.91uM
    17 6aog:A (3.2) BS03 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... Q07422 N/A BindingDB: IC50=390nM
    18 6aog:B (3.2) BS04 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... Q07422 N/A BindingDB: IC50=390nM
    19 6nni:A (1.561) BS02 CP6 1.5.1.3 GO:0004146 ... P9WNX1 31282477
    20 6nni:B (1.561) BS02 CP6 1.5.1.3 GO:0004146 ... P9WNX1 31282477
    21 7fgw:A (2.15) BS02 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... Q07422 35715223
    22 7fgw:B (2.15) BS03 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... Q07422 35715223
    23 7fgw:C (2.15) BS02 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... Q07422 35715223
    24 7fgw:D (2.15) BS03 CP6 1.5.1.3
    2.1.1.45    		 GO:0004146 ... Q07422 35715223
    25 7opj:A (1.34) BS02 CP6 ? GO:0000166 ... O76290 34209148
    26 7opj:B (1.34) BS02 CP6 ? GO:0000166 ... O76290 34209148
    27 7opj:C (1.34) BS02 CP6 ? GO:0000166 ... O76290 34209148
    28 7opj:D (1.34) BS02 CP6 ? GO:0000166 ... O76290 34209148
    29 8a0z:A (1.7) BS02 CP6 1.5.1.3 GO:0000166 ... A0A0L0P1H8 N/A
    30 8a0z:B (1.7) BS02 CP6 1.5.1.3 GO:0000166 ... A0A0L0P1H8 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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