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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 49284 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    5001 5e79:B (3.5) BS16 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5002 5e79:C (3.5) BS02 CLA ? GO:0005737 ... Q8DIF8 26863980
    5003 5e79:C (3.5) BS03 CLA ? GO:0005737 ... Q8DIF8 26863980
    5004 5e79:C (3.5) BS04 CLA ? GO:0005737 ... Q8DIF8 26863980
    5005 5e79:C (3.5) BS05 CLA ? GO:0005737 ... Q8DIF8 26863980
    5006 5e79:C (3.5) BS06 CLA ? GO:0005737 ... Q8DIF8 26863980
    5007 5e79:C (3.5) BS07 CLA ? GO:0005737 ... Q8DIF8 26863980
    5008 5e79:C (3.5) BS08 CLA ? GO:0005737 ... Q8DIF8 26863980
    5009 5e79:C (3.5) BS09 CLA ? GO:0005737 ... Q8DIF8 26863980
    5010 5e79:C (3.5) BS10 CLA ? GO:0005737 ... Q8DIF8 26863980
    5011 5e79:C (3.5) BS11 CLA ? GO:0005737 ... Q8DIF8 26863980
    5012 5e79:C (3.5) BS12 CLA ? GO:0005737 ... Q8DIF8 26863980
    5013 5e79:C (3.5) BS13 CLA ? GO:0005737 ... Q8DIF8 26863980
    5014 5e79:C (3.5) BS14 CLA ? GO:0005737 ... Q8DIF8 26863980
    5015 5e79:D (3.5) BS03 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5016 5e79:D (3.5) BS04 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5017 5e79:D (3.5) BS06 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5018 5e79:D (3.5) BS08 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5019 5e79:D (3.5) BS09 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5020 5e79:D (3.5) BS10 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5021 5e79:H (3.5) BS01 CLA ? GO:0009523 ... Q8DJ43 26863980
    5022 5e79:H (3.5) BS02 CLA ? GO:0009523 ... Q8DJ43 26863980
    5023 5e79:H (3.5) BS03 CLA ? GO:0009523 ... Q8DJ43 26863980
    5024 5e79:H (3.5) BS04 CLA ? GO:0009523 ... Q8DJ43 26863980
    5025 5e79:I (3.5) BS01 CLA ? GO:0005737 ... Q8DJZ6 26863980
    5026 5e79:I (3.5) BS02 CLA ? GO:0005737 ... Q8DJZ6 26863980
    5027 5e79:K (3.5) BS02 CLA ? GO:0009523 ... Q9F1K9 26863980
    5028 5e79:K (3.5) BS03 CLA ? GO:0009523 ... Q9F1K9 26863980
    5029 5e79:X (3.5) BS01 CLA ? GO:0009523 ... Q9F1R6 26863980
    5030 5e79:Z (3.5) BS02 CLA ? GO:0009523 ... Q8DHJ2 26863980
    5031 5e79:a (3.5) BS04 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5032 5e79:a (3.5) BS05 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5033 5e79:a (3.5) BS07 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5034 5e79:a (3.5) BS08 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5035 5e79:a (3.5) BS09 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5036 5e79:b (3.5) BS01 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5037 5e79:b (3.5) BS02 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5038 5e79:b (3.5) BS03 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5039 5e79:b (3.5) BS04 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5040 5e79:b (3.5) BS05 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5041 5e79:b (3.5) BS06 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5042 5e79:b (3.5) BS07 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5043 5e79:b (3.5) BS08 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5044 5e79:b (3.5) BS09 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5045 5e79:b (3.5) BS10 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5046 5e79:b (3.5) BS11 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5047 5e79:b (3.5) BS12 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5048 5e79:b (3.5) BS13 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5049 5e79:b (3.5) BS14 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5050 5e79:b (3.5) BS15 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5051 5e79:b (3.5) BS16 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5052 5e79:c (3.5) BS02 CLA ? GO:0005737 ... Q8DIF8 26863980
    5053 5e79:c (3.5) BS03 CLA ? GO:0005737 ... Q8DIF8 26863980
    5054 5e79:c (3.5) BS04 CLA ? GO:0005737 ... Q8DIF8 26863980
    5055 5e79:c (3.5) BS05 CLA ? GO:0005737 ... Q8DIF8 26863980
    5056 5e79:c (3.5) BS06 CLA ? GO:0005737 ... Q8DIF8 26863980
    5057 5e79:c (3.5) BS07 CLA ? GO:0005737 ... Q8DIF8 26863980
    5058 5e79:c (3.5) BS08 CLA ? GO:0005737 ... Q8DIF8 26863980
    5059 5e79:c (3.5) BS09 CLA ? GO:0005737 ... Q8DIF8 26863980
    5060 5e79:c (3.5) BS10 CLA ? GO:0005737 ... Q8DIF8 26863980
    5061 5e79:c (3.5) BS11 CLA ? GO:0005737 ... Q8DIF8 26863980
    5062 5e79:c (3.5) BS12 CLA ? GO:0005737 ... Q8DIF8 26863980
    5063 5e79:c (3.5) BS13 CLA ? GO:0005737 ... Q8DIF8 26863980
    5064 5e79:c (3.5) BS14 CLA ? GO:0005737 ... Q8DIF8 26863980
    5065 5e79:d (3.5) BS03 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5066 5e79:d (3.5) BS05 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5067 5e79:d (3.5) BS06 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5068 5e79:d (3.5) BS08 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5069 5e79:d (3.5) BS09 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5070 5e79:h (3.5) BS01 CLA ? GO:0009523 ... Q8DJ43 26863980
    5071 5e79:h (3.5) BS02 CLA ? GO:0009523 ... Q8DJ43 26863980
    5072 5e79:h (3.5) BS03 CLA ? GO:0009523 ... Q8DJ43 26863980
    5073 5e79:h (3.5) BS04 CLA ? GO:0009523 ... Q8DJ43 26863980
    5074 5e79:h (3.5) BS05 CLA ? GO:0009523 ... Q8DJ43 26863980
    5075 5e79:h (3.5) BS06 CLA ? GO:0009523 ... Q8DJ43 26863980
    5076 5e79:i (3.5) BS01 CLA ? GO:0005737 ... Q8DJZ6 26863980
    5077 5e79:i (3.5) BS02 CLA ? GO:0005737 ... Q8DJZ6 26863980
    5078 5e79:k (3.5) BS02 CLA ? GO:0009523 ... Q9F1K9 26863980
    5079 5e79:k (3.5) BS03 CLA ? GO:0009523 ... Q9F1K9 26863980
    5080 5e7c:A (4.5) BS03 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5081 5e7c:A (4.5) BS04 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5082 5e7c:A (4.5) BS06 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5083 5e7c:A (4.5) BS08 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5084 5e7c:A (4.5) BS10 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5085 5e7c:B (4.5) BS01 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5086 5e7c:B (4.5) BS02 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5087 5e7c:B (4.5) BS03 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5088 5e7c:B (4.5) BS04 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5089 5e7c:B (4.5) BS05 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5090 5e7c:B (4.5) BS06 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5091 5e7c:B (4.5) BS07 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5092 5e7c:B (4.5) BS08 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5093 5e7c:B (4.5) BS09 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5094 5e7c:B (4.5) BS10 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5095 5e7c:B (4.5) BS11 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5096 5e7c:B (4.5) BS12 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5097 5e7c:B (4.5) BS13 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5098 5e7c:B (4.5) BS14 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5099 5e7c:B (4.5) BS15 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5100 5e7c:B (4.5) BS16 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5101 5e7c:C (4.5) BS02 CLA ? GO:0005737 ... Q8DIF8 26863980
    5102 5e7c:C (4.5) BS03 CLA ? GO:0005737 ... Q8DIF8 26863980
    5103 5e7c:C (4.5) BS04 CLA ? GO:0005737 ... Q8DIF8 26863980
    5104 5e7c:C (4.5) BS05 CLA ? GO:0005737 ... Q8DIF8 26863980
    5105 5e7c:C (4.5) BS06 CLA ? GO:0005737 ... Q8DIF8 26863980
    5106 5e7c:C (4.5) BS07 CLA ? GO:0005737 ... Q8DIF8 26863980
    5107 5e7c:C (4.5) BS08 CLA ? GO:0005737 ... Q8DIF8 26863980
    5108 5e7c:C (4.5) BS09 CLA ? GO:0005737 ... Q8DIF8 26863980
    5109 5e7c:C (4.5) BS10 CLA ? GO:0005737 ... Q8DIF8 26863980
    5110 5e7c:C (4.5) BS11 CLA ? GO:0005737 ... Q8DIF8 26863980
    5111 5e7c:C (4.5) BS12 CLA ? GO:0005737 ... Q8DIF8 26863980
    5112 5e7c:C (4.5) BS13 CLA ? GO:0005737 ... Q8DIF8 26863980
    5113 5e7c:C (4.5) BS14 CLA ? GO:0005737 ... Q8DIF8 26863980
    5114 5e7c:D (4.5) BS01 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5115 5e7c:D (4.5) BS02 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5116 5e7c:D (4.5) BS05 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5117 5e7c:D (4.5) BS07 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5118 5e7c:D (4.5) BS08 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5119 5e7c:D (4.5) BS09 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5120 5e7c:H (4.5) BS01 CLA ? GO:0009523 ... Q8DJ43 26863980
    5121 5e7c:H (4.5) BS02 CLA ? GO:0009523 ... Q8DJ43 26863980
    5122 5e7c:H (4.5) BS03 CLA ? GO:0009523 ... Q8DJ43 26863980
    5123 5e7c:H (4.5) BS04 CLA ? GO:0009523 ... Q8DJ43 26863980
    5124 5e7c:H (4.5) BS05 CLA ? GO:0009523 ... Q8DJ43 26863980
    5125 5e7c:H (4.5) BS06 CLA ? GO:0009523 ... Q8DJ43 26863980
    5126 5e7c:I (4.5) BS01 CLA ? GO:0005737 ... Q8DJZ6 26863980
    5127 5e7c:I (4.5) BS02 CLA ? GO:0005737 ... Q8DJZ6 26863980
    5128 5e7c:K (4.5) BS02 CLA ? GO:0009523 ... Q9F1K9 26863980
    5129 5e7c:K (4.5) BS03 CLA ? GO:0009523 ... Q9F1K9 26863980
    5130 5e7c:X (4.5) BS01 CLA ? GO:0009523 ... Q9F1R6 26863980
    5131 5e7c:Z (4.5) BS02 CLA ? GO:0009523 ... Q8DHJ2 26863980
    5132 5e7c:a (4.5) BS03 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5133 5e7c:a (4.5) BS04 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5134 5e7c:a (4.5) BS06 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5135 5e7c:a (4.5) BS07 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5136 5e7c:a (4.5) BS09 CLA 1.10.3.9 GO:0005506 ... P0A444 26863980
    5137 5e7c:b (4.5) BS01 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5138 5e7c:b (4.5) BS02 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5139 5e7c:b (4.5) BS03 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5140 5e7c:b (4.5) BS04 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5141 5e7c:b (4.5) BS05 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5142 5e7c:b (4.5) BS06 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5143 5e7c:b (4.5) BS07 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5144 5e7c:b (4.5) BS08 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5145 5e7c:b (4.5) BS09 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5146 5e7c:b (4.5) BS10 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5147 5e7c:b (4.5) BS11 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5148 5e7c:b (4.5) BS12 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5149 5e7c:b (4.5) BS13 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5150 5e7c:b (4.5) BS14 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5151 5e7c:b (4.5) BS15 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5152 5e7c:b (4.5) BS16 CLA ? GO:0009521 ... Q8DIQ1 26863980
    5153 5e7c:c (4.5) BS02 CLA ? GO:0005737 ... Q8DIF8 26863980
    5154 5e7c:c (4.5) BS03 CLA ? GO:0005737 ... Q8DIF8 26863980
    5155 5e7c:c (4.5) BS04 CLA ? GO:0005737 ... Q8DIF8 26863980
    5156 5e7c:c (4.5) BS05 CLA ? GO:0005737 ... Q8DIF8 26863980
    5157 5e7c:c (4.5) BS06 CLA ? GO:0005737 ... Q8DIF8 26863980
    5158 5e7c:c (4.5) BS07 CLA ? GO:0005737 ... Q8DIF8 26863980
    5159 5e7c:c (4.5) BS08 CLA ? GO:0005737 ... Q8DIF8 26863980
    5160 5e7c:c (4.5) BS09 CLA ? GO:0005737 ... Q8DIF8 26863980
    5161 5e7c:c (4.5) BS10 CLA ? GO:0005737 ... Q8DIF8 26863980
    5162 5e7c:c (4.5) BS11 CLA ? GO:0005737 ... Q8DIF8 26863980
    5163 5e7c:c (4.5) BS12 CLA ? GO:0005737 ... Q8DIF8 26863980
    5164 5e7c:c (4.5) BS13 CLA ? GO:0005737 ... Q8DIF8 26863980
    5165 5e7c:c (4.5) BS14 CLA ? GO:0005737 ... Q8DIF8 26863980
    5166 5e7c:d (4.5) BS02 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5167 5e7c:d (4.5) BS03 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5168 5e7c:d (4.5) BS05 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5169 5e7c:d (4.5) BS07 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5170 5e7c:d (4.5) BS09 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5171 5e7c:d (4.5) BS10 CLA 1.10.3.9 GO:0005506 ... Q8CM25 26863980
    5172 5e7c:h (4.5) BS01 CLA ? GO:0009523 ... Q8DJ43 26863980
    5173 5e7c:h (4.5) BS02 CLA ? GO:0009523 ... Q8DJ43 26863980
    5174 5e7c:h (4.5) BS03 CLA ? GO:0009523 ... Q8DJ43 26863980
    5175 5e7c:h (4.5) BS04 CLA ? GO:0009523 ... Q8DJ43 26863980
    5176 5e7c:h (4.5) BS05 CLA ? GO:0009523 ... Q8DJ43 26863980
    5177 5e7c:h (4.5) BS06 CLA ? GO:0009523 ... Q8DJ43 26863980
    5178 5e7c:i (4.5) BS01 CLA ? GO:0005737 ... Q8DJZ6 26863980
    5179 5e7c:i (4.5) BS02 CLA ? GO:0005737 ... Q8DJZ6 26863980
    5180 5e7c:k (4.5) BS02 CLA ? GO:0009523 ... Q9F1K9 26863980
    5181 5e7c:k (4.5) BS03 CLA ? GO:0009523 ... Q9F1K9 26863980
    5182 5e7c:x (4.5) BS01 CLA ? GO:0009523 ... Q9F1R6 26863980
    5183 5e7c:z (4.5) BS02 CLA ? GO:0009523 ... Q8DHJ2 26863980
    5184 5gth:A (2.5) BS02 CLA 1.10.3.9 GO:0005506 ... P51765 28219079
    5185 5gth:A (2.5) BS03 CLA 1.10.3.9 GO:0005506 ... P51765 28219079
    5186 5gth:A (2.5) BS04 CLA 1.10.3.9 GO:0005506 ... P51765 28219079
    5187 5gth:A (2.5) BS06 CLA 1.10.3.9 GO:0005506 ... P51765 28219079
    5188 5gth:B (2.5) BS01 CLA ? GO:0009521 ... D0VWR1 28219079
    5189 5gth:B (2.5) BS02 CLA ? GO:0009521 ... D0VWR1 28219079
    5190 5gth:B (2.5) BS03 CLA ? GO:0009521 ... D0VWR1 28219079
    5191 5gth:B (2.5) BS04 CLA ? GO:0009521 ... D0VWR1 28219079
    5192 5gth:B (2.5) BS05 CLA ? GO:0009521 ... D0VWR1 28219079
    5193 5gth:B (2.5) BS06 CLA ? GO:0009521 ... D0VWR1 28219079
    5194 5gth:B (2.5) BS07 CLA ? GO:0009521 ... D0VWR1 28219079
    5195 5gth:B (2.5) BS08 CLA ? GO:0009521 ... D0VWR1 28219079
    5196 5gth:B (2.5) BS09 CLA ? GO:0009521 ... D0VWR1 28219079
    5197 5gth:B (2.5) BS10 CLA ? GO:0009521 ... D0VWR1 28219079
    5198 5gth:B (2.5) BS11 CLA ? GO:0009521 ... D0VWR1 28219079
    5199 5gth:B (2.5) BS12 CLA ? GO:0009521 ... D0VWR1 28219079
    5200 5gth:B (2.5) BS13 CLA ? GO:0009521 ... D0VWR1 28219079

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218