1i7m A 2.24 BS02 CG A 1 X68 F223 S229 H243 I244 E247 X1 F149 S155 H169 I170 E173 S229 H243 S154 H168 4.1.1.50 0004014,0006597,0008295 ic50=0.23nM -logKd/Ki=9.64, IC50=0.23nM P17707 11583147 375 cSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAGYCMGRMNSDCWYLYTLDFQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCPQKIEGFKRLDCQSAMFNDYNFVFTSFAKKQ 1i7m B 2.24 BS01 CG A 1 F7 L65 S66 E67 F4 L55 S56 E57 E67 E57 4.1.1.50 0004014,0008295 -logKd/Ki=9.64, IC50=0.23nM P17707 11583147 375 AHFFEGTEKLLEVWFSRGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE 1i7m C 2.24 BS02 CG D 1 X1068 C1082 F1223 C1226 S1229 I1244 T1245 E1247 X1 C15 F149 C152 S155 I170 T171 E173 S1229 H1243 S154 H168 4.1.1.50 0004014,0006597,0008295 P17707 11583147 1375 cSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAGYCMGRMNSDCWYLYTLDFQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCPQKIEGFKRLDCQSAMFNDYNFVFTSFAKKQ 1i7m D 2.24 BS01 CG D 1 L1065 S1066 E1067 L53 S54 E55 E1067 E55 4.1.1.50 0004014,0008295 ic50=0.23nM P17707 11583147 1375 HFFEGTEKLLEVWFSGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE