1gqc B 2.6 BS02 C5P B 1 P8 A9 R10 E74 S75 G76 R79 Q96 G97 P8 A9 R10 E74 S75 G76 R79 Q96 G97 2.7.7.38 0005737,0005829,0008690,0009103,0016779,0033468 P42216 11802716 1243 SKAVIVIPARYGSSRLPGKPLLDIVGKPMIQHVYERALQVAGVAEVWVATDDPRVEQAVQAFGGKAIMTRNDHESGTDRLVEVMHKVEADIYINLQGDEPMIRPRDVETLLQGMRDDPALPVATLCHAISAAEAAEPSTVKVVVNTRQDALYFSRSPIPYPRNAEKARYLKHVGIYAYRRDVLQNYSQLPESMPEQAESLEQLRLMNAGINIRTFEVAATGPGVDTPACLEKVRALMAQEL 1h47 A 1.99 BS03 C5P A 1 K104 M105 L106 A131 T132 T133 K105 M106 L107 A132 T133 T134 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 1159 EMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h47 A 1.99 BS04 C5P B 1 D56 G58 D57 G59 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 1157 EMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h47 B 1.99 BS02 C5P B 1 A100 K104 M105 L106 A131 T132 T133 A102 K106 M107 L108 A133 T134 T135 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 1157 LEMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h47 C 1.99 BS02 C5P A 1 D56 G58 D57 G59 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 1159 EMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h47 C 1.99 BS03 C5P C 1 A100 K104 M105 L106 A131 T132 T133 A101 K105 M106 L107 A132 T133 T134 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 1157 EMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h47 D 1.99 BS03 C5P D 1 A100 K104 M105 L106 A131 T132 T133 A101 K105 M106 L107 A132 T133 T134 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 1159 EMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h47 D 1.99 BS04 C5P E 1 D56 G58 D57 G59 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 1157 EMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h47 E 1.99 BS02 C5P E 1 A100 K104 M105 L106 A131 T132 T133 A102 K106 M107 L108 A133 T134 T135 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 1157 LEMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h47 E 1.99 BS04 C5P F 1 D56 G58 D58 G60 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 1157 LEMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h47 F 1.99 BS02 C5P D 1 D56 G58 D57 G59 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 1159 EMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h47 F 1.99 BS03 C5P F 1 A100 M105 L106 A131 T132 T133 A101 M106 L107 A132 T133 T134 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 1157 EMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h48 A 2.3 BS03 C5P A 1 A100 K104 M105 L106 A131 T132 T133 A101 K105 M106 L107 A132 T133 T134 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 203 EMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h48 A 2.3 BS05 C5P B 1 D56 G58 D57 G59 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 901 EMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h48 B 2.3 BS01 C5P B 1 A100 K104 M105 L106 A131 T132 T133 A102 K106 M107 L108 A133 T134 T135 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 901 LEMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h48 C 2.3 BS01 C5P A 1 D56 G58 D58 G60 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 203 LEMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h48 C 2.3 BS03 C5P C 1 A100 K104 M105 L106 A131 T132 T133 A102 K106 M107 L108 A133 T134 T135 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 901 LEMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h48 D 2.3 BS04 C5P D 1 A100 K104 M105 L106 A131 T132 T133 A102 K106 M107 L108 A133 T134 T135 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 204 LEMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h48 E 2.3 BS01 C5P E 1 A100 K104 M105 L106 T132 T133 A101 K105 M106 L107 T133 T134 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 901 EMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h48 E 2.3 BS05 C5P F 1 D56 G58 D57 G59 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 901 EMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h48 F 2.3 BS02 C5P D 1 D56 G58 D58 G60 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 204 LEMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h48 F 2.3 BS04 C5P F 1 A100 K104 M105 L106 A131 T132 T133 A102 K106 M107 L108 A133 T134 T135 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 15608374 901 LEMRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1h7f B 2.12 BS01 C5P B 1 P8 A9 R10 K19 H73 E74 S75 R79 Q96 G97 P8 A9 R10 K19 H73 E74 S75 R79 Q96 G97 2.7.7.38 0005737,0005829,0008690,0009103,0016779,0033468 P42216 11545592 1242 SKAVIVIPARYGSSRLPGKPLLDIVGKPMIQHVYERALQVAGVAEVWVATDDPRVEQAVQAFGGKAIMTRNDHESGTDRLVEVMHKVEADIYINLQGDEPMIRPRDVETLLQGMRDDPALPVATLCHAISAAEAAEPSTVKVVVNTRQDALYFSRSPIPYPRNAEKARYLKHVGIYAYRRDVLQNYSQLPESMPEQAESLEQLRLMNAGINIRTFEVAATGPGVDTPACLEKVRALMAQEL 1h7t B 2.48 BS01 C5P B 1 P8 R10 H73 E74 R79 Q96 G97 P8 R10 H73 E74 R79 Q96 G97 2.7.7.38 0005737,0005829,0008690,0009103,0016779,0033468 P42216 11545592 1242 SKAVIVIPARYGSSRLPGKPLLDIVGKPMIQHVYERALQVAGVAEVWVATDDPRVEQAVQAFGGKAIMTRNDHESGTDRLVEVMHKVEADIYINLQGDEPMIRPRDVETLLQGMRDDPALPVATLCHAISAAEAAEPSTVKVVVNTRQDALYFSRSPIPYPRNAEKARYLKHVGIYAYRRDVLQNYSQLPESMPEQAESLEQLRLMNAGINIRTFEVAATGPGVDTPACLEKVRALMAQEL 1iv4 A 1.55 BS02 C5P A 1 L100 K104 L105 G106 F131 K132 T133 E135 L99 K103 L104 G105 F130 K131 T132 E134 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q8RQP5 12499535 1602 RIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAAMHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREAMRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLMRLPQDRIGLTFKTSEGLAPSHVQARAVVLLD 1iv4 A 1.55 BS03 C5P C 1 D56 G58 D55 G57 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q8RQP5 12499535 1601 RIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAAMHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREAMRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLMRLPQDRIGLTFKTSEGLAPSHVQARAVVLLD 1iv4 B 1.55 BS01 C5P A 1 D256 G258 D55 G57 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q8RQP5 12499535 1602 RIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAAMHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREAMRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLMRLPQDRIGLTFKTSEGLAPSHVQARAVVLLD 1iv4 B 1.55 BS03 C5P B 1 L300 K304 L305 G306 F331 K332 T333 E335 L99 K103 L104 G105 F130 K131 T132 E134 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q8RQP5 12499535 1603 RIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAAMHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREAMRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLMRLPQDRIGLTFKTSEGLAPSHVQARAVVLLD 1iv4 C 1.55 BS01 C5P B 1 D456 G458 D55 G57 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q8RQP5 12499535 1603 RIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAAMHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREAMRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLMRLPQDRIGLTFKTSEGLAPSHVQARAVVLLD 1iv4 C 1.55 BS03 C5P C 1 L500 K504 L505 G506 F531 K532 T533 E535 L99 K103 L104 G105 F130 K131 T132 E134 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q8RQP5 12499535 1601 RIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAAMHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREAMRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLMRLPQDRIGLTFKTSEGLAPSHVQARAVVLLD 1iv4 D 1.55 BS02 C5P D 1 L1100 K1104 L1105 G1106 F1131 K1132 T1133 L99 K103 L104 G105 F130 K131 T132 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q8RQP5 12499535 1605 RIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAAMHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREAMRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLMRLPQDRIGLTFKTSEGLAPSHVQARAVVLLD 1iv4 D 1.55 BS03 C5P F 1 D1056 G1058 D55 G57 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q8RQP5 12499535 1604 RIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAAMHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREAMRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLMRLPQDRIGLTFKTSEGLAPSHVQARAVVLLD 1iv4 E 1.55 BS01 C5P D 1 D1256 G1258 D55 G57 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q8RQP5 12499535 1605 RIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAAMHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREAMRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLMRLPQDRIGLTFKTSEGLAPSHVQARAVVLLD 1iv4 E 1.55 BS03 C5P F 2 L1300 K1304 L1305 G1306 F1331 K1332 T1333 L99 K103 L104 G105 F130 K131 T132 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q8RQP5 12499535 1606 RIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAAMHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREAMRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLMRLPQDRIGLTFKTSEGLAPSHVQARAVVLLD 1iv4 F 1.55 BS02 C5P F 1 L1500 K1504 L1505 G1506 F1531 K1532 T1533 L99 K103 L104 G105 F130 K131 T132 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q8RQP5 12499535 1604 RIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAAMHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREAMRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLMRLPQDRIGLTFKTSEGLAPSHVQARAVVLLD 1iv4 F 1.55 BS03 C5P F 2 D1456 G1458 D55 G57 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q8RQP5 12499535 1606 RIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAAMHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREAMRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLMRLPQDRIGLTFKTSEGLAPSHVQARAVVLLD 1jy8 A 2.5 BS02 C5P A 1 D56 G58 D56 G58 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 11829504 669 MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLI 1knj A 2.8 BS02 C5P A 1 A100 K104 M105 L106 A131 T132 T133 A100 K104 M105 L106 A131 T132 T133 4.6.1.12 0005515,0006744,0008270,0008299,0008685,0016114,0016829,0019288,0030145,0042802,0046872 P62617 11786530 201 MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIK 1lp6 A 1.9 BS01 C5P A 1 A18 D20 K42 S158 P180 G202 R203 A10 D12 K34 S150 P172 G185 R186 4.1.1.23 0004590,0005829,0006207,0006221,0016831,0044205 O26232 12011084 2001 MDVMNRLILAMDLMNRDDALRVTGEVREYIDTVKIGYPLVLSEGMDIIAEFRKRFGCRIIADFKVADIPETNEKICRATFKAGADAIIVHGFPGADSVRACLNVAEEMGREVFLLTEMSHPGAEMFIQGAADEIARMGVDLGVKNYVGPSTRPERLSRLREIIGQDSFLISPGETLRFADAIIVGRSIYLADNPAAAAAGIIES 1lp6 B 1.9 BS01 C5P B 1 A1018 D1020 K1042 S1158 P1180 G1202 R1203 A8 D10 K32 S148 P170 G187 R188 K1042 D1070 K1072 D1075 K32 D60 K62 D65 4.1.1.23 0004590,0005829,0006207,0006221,0016831,0044205 O26232 12011084 2002 VMNRLILAMDLMNRDDALRVTGEVREYIDTVKIGYPLVLSEGMDIIAEFRKRFGCRIIADFKVADIPETNEKICRATFKAGADAIIVHGFPGADSVRACLNVAEEMGREVFLLTEMSHPGAEMFIQGAADEIARMGVDLGVKNYVGPSTRPERLSRLREIIGQDSFLISPGGDPGETLRFADAIIVGRSIYLADNPAAAAAGIIESIKDLLIPE 1qf9 A 1.7 BS03 C5P A 1 G38 L41 R42 E63 I64 V65 G90 R93 R137 R148 G38 L41 R42 E63 I64 V65 G90 R93 R137 R148 K19 R93 R131 R137 R148 K19 R93 R131 R137 R148 2.7.4.14 0000287,0004127,0005524,0005634,0005737,0006139,0006207,0006221,0006225,0009041,0016301,0016310,0016776,0019205,0033862,0036430,0036431,0043100,0043173,0046705,0046940,0072528 P20425 10426946 196 MEKSKPNVVFVLGGPGSGKGTQCANIVRDFGWVHLSAGDLLRQEQQSGSKDGEMIATMIKNGEIVPSIVTVKLLKNAIDANQGKNFLVDGFPRNEENNNSWEENMKDFVDTKFVLFFDCPEEVMTQRLLKRGESSGRSDDNIESIKKRFNTFNVQTKLVIDHYNKFDKVKIIPANRDVNEVYNDVENLFKSMGF 1rnm E 2.0 BS01 C5P E 1 H12 V43 N44 T45 F120 H12 V43 N44 T45 F120 H12 K41 H119 F120 D121 H12 K41 H119 F120 D121 4.6.1.18 0003676,0004519,0004522,0004540,0005515,0005576,0016829,0050830 -logKd/Ki=3.07, Ki=844.2uM P61823 200 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 1rnn E 1.8 BS01 C5P E 1 H12 N44 T45 H119 F120 H12 N44 T45 H119 F120 H12 K41 H119 F120 D121 H12 K41 H119 F120 D121 4.6.1.18 0003676,0004519,0004522,0004540,0005515,0005576,0016829,0050830 P61823 200 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 1ro8 A 2.05 BS01 C5P A 1 G10 N31 T131 S132 G133 I153 D154 F155 Y156 S161 Y162 G13 N34 T134 S135 G136 I156 D157 F158 Y159 S164 Y165 R129 Y156 Y162 H188 R132 Y159 Y165 H178 2.4.99.- Q9LAK3 14730352 2001 GSHMKKVIIAGNGPSLKEIDYSRLPNDFDVFRCNQFYFEDKYYLGKKCKAVFYNPSLFFEQYYTLKHLIQNQEYETELIMCSNYNQAHLENENFVKTFYDYFPDAHLGYDFFKQLKDFNAYFKFHEIYFNQRITSGVYMCAVAIALGYKEIYLSGIDFYQNGSSYAFDTKQKNLLKLHSKNTDIKALEFLEKTYKIKLYCLCPNSLLANFIGLAPNLNSNFIIQEKNNYTKDILIPSSEAYGKFSKNI 1ro8 B 2.05 BS01 C5P B 1 G8 N9 G10 C30 N31 T131 S132 G133 I153 D154 F155 Y156 G8 N9 G10 C30 N31 T131 S132 G133 I153 D154 F155 Y156 R129 Y156 R129 Y156 2.4.99.- Q9LAK3 14730352 1001 MKKVIIAGNGPSLKEIDYSRLPNDFDVFRCNQFYFEDKYYLGKKCKAVFYNPSLFFEQYYTLKHLIQNQEYETELIMCSNYNQAHLENENFVKTFYDYFPDAHLGYDFFKQLKDFNAYFKFHEIYFNQRITSGVYMCAVAIALGYKEIYLSGIDFYKNTDIKALEFLEKTYKIKLYCLCPNSLLANFIGLAPNLNSNFIIQEKNNYTKDILIPSSEAYGKFSKN 1u80 A 2.85 BS01 C5P A 1 A275 V277 P308 D309 I310 V311 G326 F327 K341 K345 A93 V95 P120 D121 I122 V123 G138 F139 K153 K157 D210 D28 4.1.1.36,6.3.2.5 0004632,0004633,0010181,0015937,0015941 P0ABQ0 15530362 500 VNDLKHLNIMITAGPTREPLDPVRYISDHSSGKMGFAIAAAAARRGANVTLVSGPVSLPTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAAVADYRAATVAPEKIKKELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNVEEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLLLDEIVTRYDEKNR 1u80 B 2.85 BS01 C5P B 1 A275 V277 D309 I310 V311 G326 F327 K341 K345 A95 V97 D121 I122 V123 G138 F139 K153 K157 D210 D30 4.1.1.36,6.3.2.5 0004632,0004633,0010181,0015937,0015941 P0ABQ0 15530362 1500 SPVNDLKHLNIMITAGPTREPLDPVRYISDHSSGKMGFAIAAAAARRGANVTLVSGPVSLPTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAAVADYRAATVAPEKIELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNVEEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLLLDEIVTRYDEKNRR 1u80 C 2.85 BS01 C5P C 1 G273 A275 V277 P308 D309 I310 V311 G326 F327 K341 K345 G91 A93 V95 P119 D120 I121 V122 G137 F138 K152 K156 D210 D28 4.1.1.36,6.3.2.5 0004632,0004633,0010181,0015937,0015941 P0ABQ0 15530362 2500 VNDLKHLNIMITAGPTREPLDPVRYISDHSSGKMGFAIAAAAARRGANVTLVSGPVSLPTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAAVADYRAATVAPEKIDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNVEEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLLLDEIVTRYDEKNR 1uj2 A 1.8 BS01 C5P A 1 T29 K33 D62 Y65 F83 D84 Y112 F114 R166 R169 R176 Q184 T11 K15 D44 Y47 F65 D66 Y94 F96 R148 R151 R158 Q166 2.7.1.48 0004849,0005524,0005575,0005737,0005829,0009224,0016301,0016310,0042802,0043771,0044206,0044211 Q9BZX2 15130468 2301 EPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNG 1uj2 B 1.8 BS01 C5P B 1 T29 K33 D62 Y65 F83 D84 Y112 F114 H117 R166 R169 R174 R176 Q184 T11 K15 D44 Y47 F65 D66 Y94 F96 H99 R148 R151 R156 R158 Q166 2.7.1.48 0004849,0005524,0005575,0005737,0005829,0009224,0016301,0016310,0042802,0043771,0044206,0044211 Q9BZX2 15130468 1301 EPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNG 1w57 A 3.09 BS02 C5P A 1 D265 G267 D263 G265 2.7.7.60,4.6.1.12 0003824,0008299,0008685,0016114,0016779,0016829,0019288,0046872,0050518,0070567 Q9PM68 15466439 1372 EMSLIMLAAGNSTRFNTKVKKQFLRLGNDPLWLYATKNLSSFYPFKKIVVTSSNITYMKKFTKNYEFIEGGDTRAESLKKALELIDSEFVMVSDVARVLVSKNLFDRLIENLDKADCITPALKVADTTLFDNEALQREKIKLIQTPQISKTKLLKKALDQNLEFTDDSTAIAAMGGKIWFVEGEENARKLTFKEDLKKLDLPTPSFEIFTGNGFDVHEFGENRPLLLAGVQIHPTMGLKAHSDGDVLAHSLTDAILGAAGLGDIGELYPDTDMKFKNANSMELLKQAYDKVREIGFELINIDICVMAQSPKLKDFKQAMQSNIAHTLDLDEFRINVKATTTEKLGFIGRKEGMAVLSSVNLKYFDWTR 1w57 A 3.09 BS03 C5P A 2 L9 A10 A11 T75 R76 S79 D96 V97 K191 L7 A8 A9 T73 R74 S77 D94 V95 K189 2.7.7.60,4.6.1.12 0003824,0008299,0008685,0016114,0016779,0016829,0019288,0046872,0050518,0070567 Q9PM68 15466439 1373 EMSLIMLAAGNSTRFNTKVKKQFLRLGNDPLWLYATKNLSSFYPFKKIVVTSSNITYMKKFTKNYEFIEGGDTRAESLKKALELIDSEFVMVSDVARVLVSKNLFDRLIENLDKADCITPALKVADTTLFDNEALQREKIKLIQTPQISKTKLLKKALDQNLEFTDDSTAIAAMGGKIWFVEGEENARKLTFKEDLKKLDLPTPSFEIFTGNGFDVHEFGENRPLLLAGVQIHPTMGLKAHSDGDVLAHSLTDAILGAAGLGDIGELYPDTDMKFKNANSMELLKQAYDKVREIGFELINIDICVMAQSPKLKDFKQAMQSNIAHTLDLDEFRINVKATTTEKLGFIGRKEGMAVLSSVNLKYFDWTR 1w77 A 2.0 BS02 C5P A 1 L84 A85 G86 G87 G154 K155 E156 S160 D179 K284 L10 A11 G12 G13 G73 K74 E75 S79 D98 K196 2.7.7.60 0003824,0008299,0050518,0070567 P69834 16478479 3001 MEKSVSVILLAGGSMPKQYIPLLGQPIALYSFFTFSRMPEVKEIVVVCDPFFRDIFEEYEESIDVDLRFAIPGKERQDSVYSGLQEIDVNSELVCIHDSARPLVNTEDVEKVLKDGSAVGAAVLGVPAKATIKEVNSDSLVVTLWEMQTPQVIKPELLKKGFELVKSEGLEVTDVSIVEYLKHPVYVSQGSYTNIKVTTPDDLLLAERILSE 1xrj A 2.0 BS01 C5P A 1 T29 K33 Y65 F83 D84 Y112 F114 H117 R166 R169 R174 R176 Q184 T10 K14 Y46 F64 D65 Y93 F95 H98 R147 R150 R155 R157 Q165 2.7.1.48 0004849,0005524,0005575,0005737,0005829,0009224,0016301,0016310,0042802,0043771,0044206,0044211 Q9BZX2 15735337 405 PFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILN 1xrj B 2.0 BS02 C5P B 1 T29 Y65 F83 D84 Y112 F114 H117 R166 R169 R174 R176 Q184 T11 Y47 F65 D66 Y94 F96 H99 R148 R151 R156 R158 Q166 2.7.1.48 0004849,0005524,0005575,0005737,0005829,0009224,0016301,0016310,0042802,0043771,0044206,0044211 Q9BZX2 15735337 406 EPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNG 2ex1 A 2.0 BS01 C5P A 1 G266 K309 G310 H311 P312 S336 E338 S355 S356 G242 K285 G286 H287 P288 S312 E314 S331 S332 '2.4.99.4,2.4.99.6,2.4.99.9' 0016757 Q15KI8 16475803 1427 MKTITLYLDPASLPALNQLMDFTQNNEDKTHPRIFGLSRFKIPDNIITQYQNIHFVELKDNRPTEALFTILDQYPGNIELNIHLNIAHSVQLIRPILAYRFAHLDRVSIQQLNLYDDGSMEYVDLEKEENKDISAEIKQAEKQLSHYLLTGKIKFDNPTIARYVWQSAFPVKYHFLSTDYFEKAEFLQPLKEYLAENYQKMDWTAYQQLTPEQQAFYLTLVGFNDEVKQSLEVQQAKFIFTGTTTAEGNTDVREYYAQQQLNLLNHFTQAEGDLFIGDHYKIYFKGHPRGGEINDYILNNAKNITNIPANISFEVLMMTGLLPDKVGGVASSLYFSLPKEKISHIIFTSNKNNPYVKVMRRLGIIDASQVIFWDSLKQL 2gn2 A 2.5 BS01 C5P A 1 R53 T54 G55 A116 D119 Y120 N314 R51 T52 G53 A114 D117 Y118 N312 K58 A83 Q209 V213 G215 G237 I310 S311 K56 A81 Q207 V211 G213 G235 I308 S309 4.3.1.17,4.3.1.19 0000166,0003941,0004794,0006520,0006565,0006567,0009097,0016829,0030170,0070689 P11954 17046821 400 ITYDLPVAIEDILEAKKRLAGKIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTEAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVETEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAIAIKSINPTIKVIGVQAENVHGMAASYYTGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVITEGAGALACAALLSGKLDSHIQNRKTVSIISGGNIDLSRVSQITGLVD 2h92 A 2.3 BS01 C5P A 1 T34 G35 Y38 R39 V95 R105 G125 R126 R176 D180 R183 T32 G33 Y36 R37 V93 R103 G123 R124 R174 D178 R181 2.7.4.25 0004127,0005524,0005737,0005829,0006139,0006220,0009058,0015949,0016301,0016310,0036430,0036431,0044281,0046940 P63807 16880539 1300 AINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQTTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKGIVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYDMNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQI 2h92 B 2.3 BS02 C5P B 1 T34 G35 Y38 R39 V95 A99 R105 G125 R126 R176 D180 R183 T32 G33 Y36 R37 V93 A97 R103 G123 R124 R174 D178 R181 2.7.4.25 0004127,0005524,0005737,0005829,0006139,0006220,0009058,0015949,0016301,0016310,0036430,0036431,0044281,0046940 P63807 16880539 1301 AINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQTTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKGIVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYDMNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQI 2h92 C 2.3 BS02 C5P C 1 K16 T34 G35 Y38 R39 V95 A99 R105 G125 R126 R176 D180 R183 K14 T32 G33 Y36 R37 V93 A97 R103 G123 R124 R174 D178 R181 2.7.4.25 0004127,0005524,0005737,0005829,0006139,0006220,0009058,0015949,0016301,0016310,0036430,0036431,0044281,0046940 P63807 16880539 1302 AINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQTTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKGIVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYDMNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQI 2ii6 A 1.75 BS01 C5P A 1 G266 K309 G310 P312 F337 E338 S355 S356 G242 K285 G286 P288 F313 E314 S331 S332 2.4.99.4 0016757 Q15KI8 1427 MKTITLYLDPASLPALNQLMDFTQNNEDKTHPRIFGLSRFKIPDNIITQYQNIHFVELKDNRPTEALFTILDQYPGNIELNIHLNIAHSVQLIRPILAYRFKHLDRVSIQQLNLYDNGSMEYVDLEKEENKDISAEIKQAEKQLSHYLLTGKIKFDNPTIARYVWQSAFPVKYHFLSTDYFEKAEFLQPLKEYLAENYQKMDWTAYQQLTPEQQAFYLTLVGFNDEVKQSLEVQQAKFIFTGTTTWEGNTDVREYYAQQQLNLLNHFTQAEGDLFIGDHYKIYFKGHPRGGEINDYILNNAKNITNIPANISFEVLMMTGLLPDKVGGVASSLYFSLPKEKISHIIFTSNKQVKSKEDALNNPYVKVMRRLGIIDESQVIFWDSLKQLGGGLE 2iib A 2.2 BS01 C5P A 1 S36 G266 K309 G310 H311 P312 S336 F337 E338 S355 S356 L357 S12 G242 K285 G286 H287 P288 S312 F313 E314 S331 S332 L333 2.4.99.4 0016757 Q15KI8 1427 MKTITLYLDPASLPALNQLMDFTQNNEDKTHPRIFGLSRFKIPDNIITQYQNIHFVELKDNRPTEALFTILDQYPGNIELNIHLNIAHSVQLIRPILAYRFKHLDRVSIQQLNLYDNGSMEYVDLEKEENKDISAEIKQAEKQLSHYLLTGKIKFDNPTIARYVWQSAFPVKYHFLSTDYFEKAEFLQPLKEYLAENYQKMDWTAYQQLTPEQQAFYLTLVGFNDEVKQSLEVQQAKFIFTGTTTWEGNTDVREYYAQQQLNLLNHFTQAEGDLFIGDHYKIYFKGHPRGGEINDYILNNAKNITNIPANISFEVLMMTGLLPDKVGGVASSLYFSLPKEKISHIIFTSNNPYVKVMRRLGIIDESQVIFWDSLKQL 2iiq A 2.3 BS01 C5P A 1 T265 G266 K309 G310 H311 P312 S355 L357 T241 G242 K285 G286 H287 P288 S331 L333 2.4.99.4 0016757 Q15KI8 1427 MKTITLYLDPASLPALNQLMDFTQNNEDKTHPRIFGLSRFKIPDNIITQYQNIHFVELKDNRPTEALFTILDQYPGNIELNIHLNIAHSVQLIRPILAYRFKHLDRVSIQQLNLYDDGSMEYVDLEKEENKDISAEIKQAEKQLSHYLLTGKIKFDNPTIARYVWQSAFPVKYHFLSTDYFEKAEFLQPLKEYLAENYQKMDWTAYQQLTPEQQAFYLTLVGFNDEVKQSLEVQQAKFIFTGTTTWEGNTDVREYYAQQQLNLLNHFTQAEGDLFIGDHYKIYFKGHPRGGEINDYILNNAKNITNIPANISFEVLMMTGLLPDKVGGVASSLYFSLPKEKISHIIFTSNKQVKSKEDALNNPYVKVMRRLGIIDESQVIFWDSLKQL 2iiq B 2.3 BS01 C5P B 1 G266 K309 G310 H311 P312 S355 L357 G242 K285 G286 H287 P288 S331 L333 2.4.99.4 0016757 Q15KI8 1427 MKTITLYLDPASLPALNQLMDFTQNNEDKTHPRIFGLSRFKIPDNIITQYQNIHFVELKDNRPTEALFTILDQYPGNIELNIHLNIAHSVQLIRPILAYRFKHLDRVSIQQLNLYDDGSMEYVDLEKEENKDISAEIKQAEKQLSHYLLTGKIKFDNPTIARYVWQSAFPVKYHFLSTDYFEKAEFLQPLKEYLAENYQKMDWTAYQQLTPEQQAFYLTLVGFNDEVKQSLEVQQAKFIFTGTTTWEGNTDVREYYAQQQLNLLNHFTQAEGDLFIGDHYKIYFKGHPRGGEINDYILNNAKNITNIPANISFEVLMMTGLLPDKVGGVASSLYFSLPKEKISHIIFTSNKQVKSKEDALNNPYVKVMRRLGIIDESQVIFWDSLKQL 2ilv A 2.27 BS02 C5P A 1 G266 K309 G310 H311 P312 S336 F337 E338 S355 S356 L357 G242 K285 G286 H287 P288 S312 F313 E314 S331 S332 L333 2.4.99.4 0016757 Q15KI8 17487984 1427 MKTITLYLDPASLPALNQLMDFTQNNEDKTHPRIFGLSRFKIPDNIITQYQNIHFVELKDNRPTEALFTILDQYPGNIELNIHLNIAHSVQLIRPILAYRFKHLDRVSIQQLNLYDDGSMEYVDLEKEENKDISAEIKQAEKQLSHYLLTGKIKFDNPTIARYVWQSAFPVKYHFLSTDYFEKAEFLQPLKEYLAENYQKMDWTAYQQLTPEQQAFYLTLVGFNDEVKQSLEVQQAKFIFTGTTTWEGNTDVREYYAQQQLNLLNHFTQAEGDLFIGDHYKIYFKGHPRGGEINDYILNNAKNITNIPANISFEVLMMTGLLPDKVGGVASSLYFSLPKEKISHIIFTALNNPYVKVMRRLGIIDESQVIFWDSLKQL 2ix0 A 2.44 BS01 C5P A 1 F82 F86 D102 H103 R167 F75 F79 D95 H96 R160 D201 D207 D209 D210 Y313 R500 D194 D200 D202 D203 Y306 R493 3.1.13.1 0003676,0003723,0004527,0004540,0005515,0005737,0005829,0006401,0006402,0008408,0008859,0016070,0016078 P30850 16957732 1645 DDPLLAQLKQQLHSQTPRAEGVVKATEFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPVA 2pmp A 2.3 BS02 C5P A 1 D59 G61 D59 G61 4.6.1.12 0008685,0016114 Q9CAK8 17660251 700 TLPFRIGHGFDLHRLEPGYPLIIGGIVIPHDRGCEAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPKWKGAASSVFIKEAVRLMDEAGYEIGNLDATLILQRPKISPHKETIRSNLSKLLGADPSVVNLKAKTHEKVDSLGENRSIAAHTVILLMKK 2ukd A 2.2 BS02 C5P A 1 G38 R42 E63 I64 V65 G90 R93 G35 R39 E60 I61 V62 G87 R90 K19 R93 R131 R137 R148 K16 R90 R128 R134 R145 2.7.4.14 0000287,0004127,0005524,0005634,0005737,0006139,0006207,0006221,0006225,0009041,0016301,0016310,0016776,0019205,0033862,0036430,0036431,0043100,0043173,0046705,0046940,0072528 P20425 9280438 196 SKPNVVFVLGGPGSGKGTQCANIVRDFGWVHLSAGDLLRQEQQSGSKDGEMIATMIKNGEIVPSIVTVKLLKNAIDANQGKNFLVDGFPRNEENNNSWEENMKDFVDTKFVLFFDCPEEVMTQRLLKRGESSGRSDDNIESIKKRFNTFNVQTKLVIDHYNKFDKVKIIPANRDVNEVYNDVENLFKSMGF 2vfl A 2.25 BS01 C5P A 1 T134 F179 R219 H224 T226 T47 F92 R132 H137 T139 18082768 1293 YQPNYFLSIPITNKKITAGIKVLQNSILRQDNRLTKAMVGDGSFHITLLVMQLLNEDEVNIGTDALLELKPFVEEILEGKHLTLPFHGIGTFQGQVGFVKLADGDHVSALLEIAETAKRTFQEKGILAGESRTFKPHLTFMKLSKAPMLWKKGVRKIEPGLYEQFIDHRFGEEILYQIDLCSMLKKKQSNGYYHCESSIVIGEKD 2wnb A 1.55 BS02 C5P A 1 N150 S151 M172 N173 G273 F292 G293 W300 H302 N91 S92 M113 N114 G214 F233 G234 W241 H243 Y269 H319 Y210 H249 2.4.3.2,2.4.3.4 0006486,0008373 Q02745 19820709 1344 RPCTCTRCIEEQRVSAWFDERFNRSMQPLLTAKNAHLEEDTYKWWLRLQREKQPNNLNDTIRELFQVVPGNVDPLLEKRLVSCRRCAVVGNSGNLKESYYGPQIDSHDFVLRMNKAPTEGFEADVGSKTTHHFVYPESFRELAQEVSMILVPFKTTDLEWVISATTTGRISHTYVPVPAKIKVKKEKILIYHPAFIKYVFDRWLQGHGRYPSTGILSVIFSLHICDEVDLYGFGADSKGNWHHYWEGVHDGDFESNVTTILASINKIRIFKGR 2xcu A 2.42 BS01 C5P A 1 S182 R212 F247 G248 L250 N273 E276 S183 R213 F248 G249 L251 N274 E277 2.4.99.12 0005886,0009103,0009244,0009245,0016740,0043842 O66663 22474366 400 HMQFEVLKRFFPKESLKNCKGALWVHTASIGEFNTFLPILKELKREHRILLTYFSPRAREYLKTKSDFYDCLHPLPLDNPFSVKRFEELSKPKALIVVEREFWPSLIIFTKVPKILVNAYAKGSLIEKILSKKFDLIIMRTQEDVEKFKTFGAKRVFSCGNLKFICQKGKGIKLKGEFIVAGSIHTGEVEIILKAFKEIKKTYSSLKLILVPRHIENAKIFEKKARDFGFKTSFFENLEGDVILVDRFGILKELYPVGKIAIVGGTFVNIGGHNLLEPTCWGIPVIYGPYTHKVNDLKEFLEKEGAGFEVKNETELVTKLTELLSVKKEIKVEEKSREIKGCYLEKLREFLRG 2xcu B 2.42 BS01 C5P B 1 S182 R212 F247 G248 L250 K251 H272 N273 E276 S182 R212 F247 G248 L250 K251 H272 N273 E276 2.4.99.12 0005886,0009103,0009244,0009245,0016740,0043842 O66663 22474366 400 MQFEVLKRFFPKESLKNCKGALWVHTASIGEFNTFLPILKELKREHRILLTYFSPRAREYLKTKSDFYDCLHPLPLDNPFSVKRFEELSKPKALIVVEREFWPSLIIFTKVPKILVNAYAKGSLIEKILSKKFDLIIMRTQEDVEKFKTFGAKRVFSCGNLKFICQKGKGIKLKGEFIVAGSIHTGEVEIILKAFKEIKKTYSSLKLILVPRHIENAKIFEKKARDFGFKTSFFENLEGDVILVDRFGILKELYPVGKIAIVGGTFVNIGGHNLLEPTCWGIPVIYGPYTHKVNDLKEFLEKEGAGFEVKNETELVTKLTELLSVKKEIKVEEKSREIKGCYLEKLREFLRG 2xcu C 2.42 BS01 C5P C 1 S182 R212 F247 G248 L250 N273 E276 S183 R213 F248 G249 L251 N274 E277 2.4.99.12 0005886,0009103,0009244,0009245,0016740,0043842 O66663 22474366 400 HMQFEVLKRFFPKESLKNCKGALWVHTASIGEFNTFLPILKELKREHRILLTYFSPRAREYLKTKSDFYDCLHPLPLDNPFSVKRFEELSKPKALIVVEREFWPSLIIFTKVPKILVNAYAKGSLIEKILSKKFDLIIMRTQEDVEKFKTFGAKRVFSCGNLKFICQKGKGIKLKGEFIVAGSIHTGEVEIILKAFKEIKKTYSSLKLILVPRHIENAKIFEKKARDFGFKTSFFENLEGDVILVDRFGILKELYPVGKIAIVGGTFVNIGGHNLLEPTCWGIPVIYGPYTHKVNDLKEFLEKEGAGFEVKNETELVTKLTELLSVKKEIKVEEKSREIKGCYLEKLREFLRG 2xcu D 2.42 BS01 C5P D 1 S182 V210 R212 F247 G248 L250 N273 E276 S182 V210 R212 F247 G248 L250 N273 E276 2.4.99.12 0005886,0009103,0009244,0009245,0016740,0043842 O66663 22474366 400 MQFEVLKRFFPKESLKNCKGALWVHTASIGEFNTFLPILKELKREHRILLTYFSPRAREYLKTKSDFYDCLHPLPLDNPFSVKRFEELSKPKALIVVEREFWPSLIIFTKVPKILVNAYAKGSLIEKILSKKFDLIIMRTQEDVEKFKTFGAKRVFSCGNLKFICQKGKGIKLKGEFIVAGSIHTGEVEIILKAFKEIKKTYSSLKLILVPRHIENAKIFEKKARDFGFKTSFFENLEGDVILVDRFGILKELYPVGKIAIVGGTFVNIGGHNLLEPTCWGIPVIYGPYTHKVNDLKEFLEKEGAGFEVKNETELVTKLTELLSVKKEIKVEEKSREIKGCYLEKLREFLRG 2xwm A 1.8 BS01 C5P A 1 P8 A9 A10 G11 K22 V77 D78 R79 S82 D100 K204 P7 A8 A9 G10 K21 V76 D77 R78 S81 D99 K203 2.7.7.60 0000166,0003824,0008299,0016779,0019288,0050518,0070567 A0R560 21543842 301 ATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKLVFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKEGHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLAHH 2xwm B 1.8 BS01 C5P B 1 P8 A9 A10 G11 S12 G13 K22 V77 D78 R79 S82 P7 A8 A9 G10 S11 G12 K21 V76 D77 R78 S81 2.7.7.60 0000166,0003824,0008299,0016779,0019288,0050518,0070567 A0R560 21543842 301 ATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKLVFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKEGHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLAHHHH 2yyu A 2.2 BS01 C5P A 1 D12 K34 T124 R186 G215 R216 D8 K30 T120 R182 G204 R205 K34 D61 K63 D66 T124 R216 K30 D57 K59 D62 T120 R205 4.1.1.23 0004590,0005829,0006207,0006221,0016831,0044205 Q5L0U0 1301 TPFIVALDFPSKQEVERFLRPFAGTPLFVKVGMELYYQEGPAIVAFLKEQGHAVFLDLKLHDIPNTVKQAMKGLARVGADLVNVHAAGGRRMMEAAIEGLDAGTPSGRMRPRCIAVTQLTSTDERMLHEELWISRPLVETVAHYAALAKESGLDGVVCSANEAAFIKERCGASFLAVTPGIRFADRVVTPRKARALGSDYIVIGRSLTRAADPLRTYARLQHEWN 2yyu B 2.2 BS01 C5P B 1 D12 K34 T124 P183 R186 G215 R216 D9 K31 T121 P180 R183 G208 R209 K34 D61 K63 D66 T124 R216 K31 D58 K60 D63 T121 R209 4.1.1.23 0004590,0005829,0006207,0006221,0016831,0044205 Q5L0U0 2301 HTPFIVALDFPSKQEVERFLRPFAGTPLFVKVGMELYYQEGPAIVAFLKEQGHAVFLDLKLHDIPNTVKQAMKGLARVGADLVNVHAAGGRRMMEAAIEGLDAGTPSGRMRPRCIAVTQLTSTDERMLHEELWISRPLVETVAHYAALAKESGLDGVVCSANEAAFIKERCGASFLAVTPGIRFADDAARVVTPRKARALGSDYIVIGRSLTRAADPLRTYARLQHEWN 2z4t A 2.5 BS03 C5P A 1 G361 K403 G404 H405 P406 S430 F431 E432 S449 S450 L451 G340 K382 G383 H384 P385 S409 F410 E411 S428 S429 L430 ? 0016757,0046872 A8QYL1 17962295 1427 TQSIIKNDINKTIIDEEYVNLEPINQSNISFTKHSWVQTCGTQQLLTEQNKESISLSVVAPRLDDDEKYCFDFNGVSNKGEKYITKVTLNVVAPSLEVYVDHASLPTLQQLMDIIKSEEENPTAQRYIAWGRIVPTDEQMKELNITSFALINNHTPADLVQEIVKQAQTKHRLNVKLSSNTAHSFDNLVPILKELNSFNNVTVTNIDLYDDGSAEYVNLYNWRDTLNKTDNLKIGKDYLEDVINGINEDTSNTGTSSVYNWQKLYPANYHFLRKDYLTLEPSLHELRDYIGDSLKQMQWDGFKKFNSKQQELFLSIVNFDKQKLQNEYNSSNLPNFVFTGTTVWAGNHEREYYAKQQINVINNAINESSPHYLGNSYDLFFKGHPGGGIINTLIMQNYPSMVDIPSKISFEVLMMTDMLPDAVAGIASSLYFTIPAEKIKFIVFTSTETITDRETALRSPLVQVMIKLGIVKEENVLFWADLPNCETGVCIAV 2zwi A 2.01 BS01 C5P A 1 G277 K315 G316 H317 P318 P340 F341 E342 S359 S360 V361 G241 K279 G280 H281 P282 P304 F305 E306 S323 S324 V325 2.4.99.4 0016757,0046872 A5LHX0 19467231 1 KNKTIEVYVDRATLPTIQQMTQIINENSNNKKLISWSRYPINDETLLESINGSFFKNRPELIKSLDSMILTNEIKKVIINGNTLWAVDVVNIIKSIEALGKKTEIELNFYDDGSAEYVRLYDFSRLPESEQEYKISLSKDNIQSSINGTQPFDNSIENIYGFSQLYPTTYHMLRADIFETNLPLTSLKRVISNNIKQMKWDYFTTFNSQQKNKFYNFTGFNPEKIKEQYKASPHENFIFIGTNSGTATAEQQIDILTEAKKPDSPIITNSIQGLDLFFKGHPSATYNQQIIDAHNMIEIYNKIPFEALIMTDALPDAVGGMGSSVFFSLPNTVENKFIFYKSDIENNALIQVMIELNIVNRNDVKLISDL 2zwi B 2.01 BS01 C5P B 1 G277 K315 G316 H317 P318 P340 F341 E342 S359 S360 V361 G241 K279 G280 H281 P282 P304 F305 E306 S323 S324 V325 2.4.99.4 0016757,0046872 A5LHX0 19467231 1 KNKTIEVYVDRATLPTIQQMTQIINENSNNKKLISWSRYPINDETLLESINGSFFKNRPELIKSLDSMILTNEIKKVIINGNTLWAVDVVNIIKSIEALGKKTEIELNFYDDGSAEYVRLYDFSRLPESEQEYKISLSKDNIQSSINGTQPFDNSIENIYGFSQLYPTTYHMLRADIFETNLPLTSLKRVISNNIKQMKWDYFTTFNSQQKNKFYNFTGFNPEKIKEQYKASPHENFIFIGTNSGTATAEQQIDILTEAKKPDSPIITNSIQGLDLFFKGHPSATYNQQIIDAHNMIEIYNKIPFEALIMTDALPDAVGGMGSSVFFSLPNTVENKFIFYKSDTDIENNALIQVMIELNIVNRNDVKLISDLQ 3asz A 2.25 BS01 C5P A 1 K19 D40 Y43 Y59 D60 Y88 F90 Y93 R142 R145 R150 R152 Q160 K15 D36 Y39 Y55 D56 Y84 F86 Y89 R138 R141 R146 R148 Q156 2.7.1.48 0004849,0005524,0005737,0008655,0009224,0016301,0016310,0016773,0043771,0044206,0044211 Q5SKR5 21539325 212 KPFVIGIAGGTASGKTTLAQALARTLGERVALLPMDHYYKDLGHLPLEERLRVNYDHPDAFDLALYLEHAQALLRGLPVEMPVYDFRAYTRSPRRTPVRPAPVVILEGILVLYPKELRDLMDLKVFVDADADERFIRRLKRDVLERGRSLEGVVAQYLEQVKPMHLHFVEPTKRYADVIVPRGGQNPVALEMLAAKALARLAR 3asz B 2.25 BS01 C5P B 1 T15 D40 Y43 Y59 D60 Y88 F90 Y93 R142 R145 R150 R152 Q160 T12 D37 Y40 Y56 D57 Y85 F87 Y90 R139 R142 R147 R149 Q157 2.7.1.48 0004849,0005524,0005737,0008655,0009224,0016301,0016310,0016773,0043771,0044206,0044211 Q5SKR5 21539325 212 PKPFVIGIAGGTASGKTTLAQALARTLGERVALLPMDHYYKDLGHLPLEERLRVNYDHPDAFDLALYLEHAQALLRGLPVEMPVYDFRAYTRSPRRTPVRPAPVVILEGILVLYPKELRDLMDLKVFVDADADERFIRRLKRDVLERGRSLEGVVAQYLEQVKPMHLHFVEPTKRYADVIVPRGGQNPVALEMLAAKALARLARMGAA 3djx A 1.69 BS01 C5P A 1 K41 V43 N44 T45 H119 F120 K41 V43 N44 T45 H119 F120 H12 K41 H119 F120 D121 H12 K41 H119 F120 D121 4.6.1.18 0003676,0004519,0004522,0004540,0005576,0016829,0042802,0050830,0051607 Ki=1557.9uM -logKd/Ki=2.81, Ki=1557.9uM P00669 19643512 125 KESAAAKFERQHMDSGNSPSSSSNYCNLMMCCRKMTQGKCKPVNTFVHESLADVKAVCSQKKVTCKNGQTNCYQSKSTMRITDCRETGSSKYPNCAYKTTQVEKHIIVACGGKPSVPVHFDASV 3djx B 1.69 BS01 C5P B 1 K41 V43 N44 T45 H119 F120 K41 V43 N44 T45 H119 F120 H12 K41 H119 F120 D121 H12 K41 H119 F120 D121 4.6.1.18 0003676,0004519,0004522,0004540,0005576,0016829,0042802,0050830,0051607 Ki=1557.9uM -logKd/Ki=2.81, Ki=1557.9uM P00669 19643512 201 KESAAAKFERQHMDSGNSPSSSSNYCNLMMCCRKMTQGKCKPVNTFVHESLADVKAVCSQKKVTCKNGQTNCYQSKSTMRITDCRETGSSKYPNCAYKTTQVEKHIIVACGGKPSVPVHFDASV 3elb A 2.0 BS01 C5P A 1 G220 F222 H229 F232 H307 G308 T310 S336 S338 L340 G171 F173 H180 F183 H258 G259 T261 S287 S289 L291 H65 G67 H47 G49 2.7.7.14 0003824,0004306,0006646,0009058 Q99447 400 GRRAVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTVDGRDTYEEVKQAGRYRECKRTQGVSTTDLVGRMLLWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVDFLEKVHRLAERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYAVTAELLSHFKVDLVCHGKTEIIPDRDGSDPYQEPKRRGIFRQIDSGSNLTTDLIVQRIIT 3f0f B 2.09 BS02 C5P C 1 D58 G60 D58 G60 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 23382856 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3f0f C 2.09 BS01 C5P C 1 L107 A108 A133 K134 T135 L104 A105 A130 K131 T132 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 23382856 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3f0g A 2.08 BS02 C5P B 1 D58 G60 D58 G60 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 21359640 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3f0g B 2.08 BS01 C5P B 1 A102 L107 A108 A133 K134 T135 A98 L103 A104 A129 K130 T131 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 21359640 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLSDADVLLHAITDALFGAAALGDIGRHFSDTRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVR 3f0g B 2.08 BS03 C5P C 1 D58 G60 D56 G58 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 21359640 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLSDADVLLHAITDALFGAAALGDIGRHFSDTRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVR 3f0g C 2.08 BS01 C5P C 1 A102 P105 K106 L107 A108 A133 K134 T135 A93 P96 K97 L98 A99 A124 K125 T126 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 21359640 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVR 3f0g D 2.08 BS01 C5P D 1 A102 K106 L107 A108 A133 K134 T135 A102 K106 L107 A108 A133 K134 T135 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 21359640 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3f0g D 2.08 BS03 C5P E 1 D58 G60 D58 G60 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 21359640 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3f0g E 2.08 BS01 C5P E 1 A102 L107 A108 A133 K134 T135 A91 L96 A97 A122 K123 T124 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 21359640 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHDSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3f0g E 2.08 BS03 C5P F 1 D58 G60 D58 G60 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 21359640 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHDSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3f0g F 2.08 BS01 C5P F 1 A102 K106 L107 A108 A133 K134 T135 A92 K96 L97 A98 A123 K124 T125 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q3JRA0 21359640 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFDSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVR 3f1j A 2.65 BS01 C5P A 1 Q36 F37 H112 Q34 F35 H110 ? 0016020,0020002,0030430,0039660,0042802,0044423 P0C794 19237566 300 SKHSYVELKDKVIVPGWPTLMLEIDFVGGTSRNQFLNIPFLSVKEPLQLPREKKLTDYFTIDVEPAGHSLVNIYFQIDDFLLLTLNSLSVYKDPIRKYMFLRLNKEQSKHAINAAFNVFSYRLRNIGVGPLGPDIRSSGP 3lug A 1.849 BS02 C5P A 1 Y529 K533 Q545 C546 K570 Y90 K94 Q106 C107 K131 3.1.26.n2 0003676 Kd=3.6mM Q9UKV8 20505670 10 KQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLG 3lug B 1.849 BS01 C5P B 1 Y529 K533 Q545 C546 K570 Y91 K95 Q107 C108 K132 3.1.26.n2 0003676 Kd=3.6mM Q9UKV8 20505670 2 NKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLG 3lug C 1.849 BS02 C5P C 1 Y529 K533 Q545 C546 Y90 K94 Q106 C107 3.1.26.n2 0003676 Kd=3.6mM Q9UKV8 20505670 9 KQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLG 3ukd A 1.9 BS02 C5P A 1 G38 L41 R42 E63 I64 V65 G90 R93 R137 R148 G35 L38 R39 E60 I61 V62 G87 R90 R134 R145 K19 R93 R131 R137 R148 K16 R90 R128 R134 R145 2.7.4.14 0000287,0004127,0005524,0005634,0005737,0006139,0006207,0006221,0006225,0009041,0016301,0016310,0016776,0019205,0033862,0036430,0036431,0043100,0043173,0046705,0046940,0072528 P20425 9280438 196 SKPNVVFVLGGPGSGKGTQCANIVRDFGWVHLSAGDLLRQEQQSGSKDGEMIATMIKNGEIVPSIVTVKLLKNAIDANQGKNFLVDGFPRNEENNNSWEENMKDFVDTKFVLFFDCPEEVMTQRLLKRGESSGRSDDNIESIKKRFNTFNVQTKLVIDHYNKFDKVKIIPANRDVNEVYNDVENLFKSMGF 3w8n A 2.2 BS01 C5P A 1 G34 Y37 R38 S98 A101 R107 G32 Y35 R36 S96 A99 R105 2.7.4.25 0004127,0005524,0005737,0005829,0006139,0006220,0009058,0015949,0016301,0016310,0036430,0036431,0044281,0046940 Q5SL35 301 GIVTIDGPSASGKSSVARRVAAALGVPYLSSGLLYRAAAFLALRAGVDPGDEEGLLALLEGLGVRLLAQAEGNRVLADGEDLTSFLHTPEVDRVVSAVARLPGVRAWVNRRLKEVPPPFVAEGRDMGTAVFPEAAHKFYLTASPEVRAWRRAPQAYEEVLRDLLRRDERDKAQSAPAPDALVLDTGGMTLDEVVAWVLAHI 4ber A 2.6 BS01 C5P A 1 D28 F31 Y41 R44 A234 G236 R237 D28 F31 Y41 R44 A234 G236 R237 2.7.1.- Q5ZXN6 23572077 1000 GVKIMPNLPGLYFLQAYPSEEIWRLFVDGRFWSKENGWRGYESREPGCLNAALESLCSIALQVEKSGEEFELSVDLIKRIHKKCGKKVEELQEKNPGELRTDEPVSFGIPAGRASIKGIEEFLSLVFLTEGGAEFGPGKAGPFGPRFDKNYFKNLNPEQIPDLAKQIYFDMCKYGHSNTNHFYLAVMKNVDVYLEKITQSYNKEIKTAETLDEKLKIIVKHIRMYEVLHPFRDANGRTFVNNLLNIPLMQQGLPPATFYEPNVFDLYSAEELVVVVKEAIFNTVEIIEQSKRKTPITLYGYHSSLEEQTKFRDMLDSPSYEKIKHMDFLNPEKLHLKTQKCLSSLNEQYPLHRGAIYLSDPGEIKLLLSNRNESQINQQIEQGAPPIYVGKTPAHLAVISGNMAMLDELIAKKADLSLQDYDGKTALHYAAECGNMQIMGKILKVVLSQEDAIKVLNIKDNHGKTAFHYAAEFGT 4ber B 2.6 BS01 C5P B 1 D28 F31 Y41 R44 D233 A234 G236 R237 N262 D28 F31 Y41 R44 D229 A230 G232 R233 N258 2.7.1.- Q5ZXN6 23572077 1000 GVKIMPNLPGLYFLQAYPSEEIWRLFVDGRFWSKENGWRGYESREPGCLNAALESLCSIALQVEKSGEEFELSVDLIKRIHKKCGELQEKNPGELRTDEPVSFGIPAGRASIKGIEEFLSLVFLTEGGAEFGPGKAGPFGPRFDKNYFKNLNPEQIPDLAKQIYFDMCKYGHSNTNHFYLAVMKNVDVYLEKITQSYNKEIKTAETLDEKLKIIVKHIRMYEVLHPFRDANGRTFVNNLLNIPLMQQGLPPATFYEPNVFDLYSAEELVVVVKEAIFNTVEIIEQSKRKTPITLYGYHSSLEEQTKFRDMLDSPSYEKIKHMDFSDLNPEKLHLKTQKCLSSLNEQYPLHRGAIYLSDPGEIKLLLSNRNESQINQQIEQGAPPIYVGKTPAHLAVISGNMAMLDELIAKKADLSLQDYDGKTALHYAAECGNMQIMGKILKVVLSQEDAIKVLNIKDNHGKTAFHYAAEFGTPE 4bes A 2.54 BS01 C5P A 1 D28 F31 Y41 R44 A234 N235 G236 R237 N262 D23 F26 Y36 R39 A219 N220 G221 R222 N247 2.7.1.- Q5ZXN6 23572077 1000 PNLPGLYFLQAYPSEEIWRLFVDGRFWSKENGWRGYESREPGCLNAALESLCSIALQVEKSGEEFELSVDLIKRIHKKCGPGELRTDEPVSFGIPAGRASIKGIEEFLSLVFLTEGGAEFGPGKAGPFGPRFDKNYFKNLNPEQIPDLAKQIYFDMCKYGHSNTNHFYLAVMKNVDVYLEKITQSYNKEIKTAETLDEKLKIIVKHIRMYEVLHPFRDANGRTFVNNLLNIPLMQQGLPPATFYEPNVFDLYSAEELVVVVKEAIFNTVEIIEQSKRKTPITLYGYHSSLEEQTKFRDMLDSPSYEKIKHMDFSDLNPEKLHLKTQKCLSSLNEQYPLHRGAIYLSDPGEIKLLLSNRNESQINQQIEQGAPPIYVGKTPAHLAVISGNMAMLDELIAKKADLSLQDYDGKTALHYAAECGNMQIMGKILKVVLSQEDAIKVLNIKDNHGKTAFHYAAEFGTPELISAL 4c8e A 1.9 BS02 C5P A 1 A102 K106 L107 A108 A133 K134 T135 A102 K106 L107 A108 A133 K134 T135 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1163 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8e A 1.9 BS03 C5P A 2 D10 H12 S37 H44 I59 L78 D10 H12 S37 H44 I59 L78 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1164 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8e A 1.9 BS04 C5P B 1 D58 G60 D58 G60 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1163 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8e B 1.9 BS02 C5P B 1 A102 L107 A108 A133 K134 T135 A102 L107 A108 A133 K134 T135 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1163 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8e B 1.9 BS03 C5P B 2 D10 H12 H36 H44 I59 D65 L78 D10 H12 H36 H44 I59 D65 L78 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1164 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8e B 1.9 BS04 C5P C 1 D58 G60 D58 G60 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1164 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8e C 1.9 BS01 C5P A 1 D58 G60 D58 G60 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1163 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8e C 1.9 BS03 C5P C 1 A102 L107 A108 A133 K134 T135 A102 L107 A108 A133 K134 T135 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1164 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8e C 1.9 BS04 C5P C 2 D10 H12 H36 S37 H44 I59 F63 L78 D10 H12 H36 S37 H44 I59 F63 L78 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1165 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8g A 2.0 BS02 C5P A 1 A102 P105 K106 L107 A108 A133 K134 T135 A94 P97 K98 L99 A100 A125 K126 T127 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1163 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8g A 2.0 BS03 C5P B 1 D58 G60 D58 G60 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1163 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8g B 2.0 BS02 C5P B 1 A102 P105 K106 L107 A108 A133 K134 T135 A93 P96 K97 L98 A99 A124 K125 T126 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1163 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGDADVLLHAITDALFGAAALGDIGRHFSGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8g B 2.0 BS03 C5P C 1 D58 G60 D56 G58 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1163 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGDADVLLHAITDALFGAAALGDIGRHFSGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8g C 2.0 BS01 C5P A 1 D58 G60 D58 G60 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1163 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDDSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4c8g C 2.0 BS03 C5P C 1 K106 L107 A108 A133 K134 T135 K98 L99 A100 A125 K126 T127 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 B4EC22 24410837 1163 MDVRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDDSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG 4die A 2.65 BS01 C5P A 1 G31 Y34 V94 S95 S98 R104 R126 G33 Y36 V96 S97 S100 R106 R128 2.7.4.25 0004127,0005524,0005737,0005829,0006139,0006220,0009058,0015949,0016301,0016310,0036430,0036431,0044281,0046940 B1MB31 25613812 301 SMVVAVDGPSGTGKSSVAKELARQLGASYLDTGAMYRIVTLWVLRAGVDLTDPAAIAAATDQVPMSVSSDPDAQTALLAGEDVSVPIRGNEVTGAVSAVSAVPAVRERLVRQQRELAESSGAVVVEGRDIGTVVLPDADVKIYLTASAQARAQRRNAQNVLADVQRRDHLDSTRLRPAEDALEVDTSDMTQEQVVAHLLDLVRT 4die B 2.65 BS01 C5P B 1 T30 G31 Y34 R35 V94 S98 R104 R126 T32 G33 Y36 R37 V96 S100 R106 R128 2.7.4.25 0004127,0005524,0005737,0005829,0006139,0006220,0009058,0015949,0016301,0016310,0036430,0036431,0044281,0046940 B1MB31 25613812 301 SMVVAVDGPSGTGKSSVAKELARQLGASYLDTGAMYRIVTLWVLRAGVDLTDPAAIAAATDQVPMSVSSDPDAQTALLAGEDVSVPIRGNEVTGAVSAVSAVPAVRERLVRQQRELAESSGAVVVEGRDIGTVVLPDADVKIYLTASAQARAQRRNQRRDHLDSTRAVSPLRPAEDALEVDTSDMTQEQVVAHLLDLVRTR 4die C 2.65 BS01 C5P C 1 G31 Y34 R35 V94 S98 R104 R126 G33 Y36 R37 V96 S100 R106 R128 2.7.4.25 0004127,0005524,0005737,0005829,0006139,0006220,0009058,0015949,0016301,0016310,0036430,0036431,0044281,0046940 B1MB31 25613812 301 SMVVAVDGPSGTGKSSVAKELARQLGASYLDTGAMYRIVTLWVLRAGVDLTDPAAIAAATDQVPMSVSSDPDAQTALLAGEDVSVPIRGNEVTGAVSAVSAVPAVRERLVRQQRELAESSGAVVVEGRDIGTVVLPDADVKIYLTASAQARAQRRNAQNVSEKVLADVQRRDHLDSTRAVSPLRPAEDALEVDTSDMTQEQVVAHLLDLVRTR 4die D 2.65 BS01 C5P D 1 T30 G31 Y34 R35 V94 R104 R126 T32 G33 Y36 R37 V96 R106 R128 2.7.4.25 0004127,0005524,0005737,0005829,0006139,0006220,0009058,0015949,0016301,0016310,0036430,0036431,0044281,0046940 B1MB31 25613812 301 SMVVAVDGPSGTGKSSVAKELARQLGASYLDTGAMYRIVTLWVLRAGVDLTDPAAIAAATDQVPMSVSSDPDAQTALLAGEDVSVPIRGNEVTGAVSAVSAVPAVRERLVRQQRELAESSGAVVVEGRDIGTVVLPDADVKIYLTASAQARAQRVQRRDHLDSTRAVSPLRPAEDALEVDTSDMTQEQVVAHLLDLVRTR 4dw3 A 2.35 BS01 C5P A 1 W35 H76 K80 H81 R131 W33 H74 K78 H79 R129 2.7.7.48,3.4.21.113,3.4.22.-,3.6.1.15,3.6.4.13,4.6.1.19 0003723,0033897 Q96662 22579253 1117 ENITQWNLQDNGTEGIQRAMFQRGVNRSLHGIWPEKICTGVPSHLATDTELKAIHGMMDASEKTNYTCCRLQRHEWNKHGWCNWYNIEPWILLMNKTQANLTEGQPLRECAVTCRYDRDSDLNVVTQARDSPTPLTGCKKGKNFSFAGILVQGPCNFEIAV 4dw3 B 2.35 BS01 C5P B 1 H32 W35 H76 E77 K80 H81 Q129 H30 W33 H74 E75 K78 H79 Q127 2.7.7.48,3.4.21.113,3.4.22.-,3.6.1.15,3.6.4.13,4.6.1.19 0003723,0033897 Q96662 22579253 1114 ENITQWNLQDNGTEGIQRAMFQRGVNRSLHGIWPEKICTGVPSHLATDTELKAIHGMMDASEKTNYTCCRLQRHEWNKHGWCNWYNIEPWILLMNKTQANLTEGQPLRECAVTCRYDRDSDLNVVTQARDSPTPLTGCKKGKNFSFAGILVQGPCNFEIAV 4dxl A 2.0 BS01 C5P A 1 Y36 H37 L39 S147 R163 F193 Y32 H33 L35 S143 R159 F189 K21 D148 K17 D144 2.7.1.148 0005524,0008299,0016114,0016301,0016310,0019288,0050515 B1MKD5 25613812 401 VSDWVPTGAVTVRAPGKVNLYLAVGDLRDDGYHELTTVFHAVSLADDVTVRDADVLSIDVVGQGEGTVPTDERNLAWQAAELFADHVGRAPDVSIFINKDIPVAGGMAGGSADAAAVLVAMNELWHAGVPRRDLHHLAAQLGSDVPFALHGGTALGTGRGEQLATVLARNVFHWVFAFADGGLATPQVFKEIDRLRENGDPPRLAEADELLGALAAGDARRLAPLLGNELQAAAVSLNPELRRTLRAGESAGALAGIVSGSGPTCAFLCTSADDAVQVSAELAGAGVCRTVRVASGPVHGAQVI 4emd A 1.75 BS01 C5P A 1 Y36 H37 S147 R163 F193 Y25 H26 S136 R152 F182 K21 D148 K10 D137 2.7.1.148 0005524,0008299,0016114,0016301,0016310,0019288,0050515 B1MKD5 25613812 401 GAVTVRAPGKVNLYLAVGDLRDDGYHELTTVFHAVSLADDVTVRDADVLSIDVVGQGEGTVPTDERNLAWQAAELFADHVGRAPDVSIFINKDIPVAGGMAGGSADAAAVLVAMNELWHAGVPRRDLHHLAAQLGSDVPFALHGGTALGTGRGEQLATVLARNVFHWVFAFADGGLATPQVFKEIDRLRENGDPPRLAEADELLGALAAGDARRLAPLLGNELQAAAVSLNPELRRTLRAGESAGALAGIVSGSGPTCAFLCTSADDAVQVSAELAGAGVCRTVRVASGPVHGAQVIQG 4fwr A 3.0 BS01 C5P A 1 G205 N206 D278 L279 R280 G326 I327 N330 G202 N203 D275 L276 R277 G323 I324 N327 N11 R86 H175 R236 E381 N8 R83 H172 R233 E378 2.7.2.15 0005524,0005829,0006082,0006083,0008776,0008980,0016301,0016310,0016774,0046872,0070689 O06961 23747922 503 FPVVLVINCGSSSIKFSVLDVATCDVLMAGIADGMNTENAFLSINGDKPINLAHSNYEDALKAIAFELEKRDLTDSVALIGHRIAHGGELFTQSVIITDEIIDNIRRVSPLAPLHNYANLSGIDAARHLFPAVRQVAVFDTSFHQTLAPEAYLYGLPWEYFSSLGVRRYGFHGTSHRYVSRRAYELLDLDEKDSGLIVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMAWIAKETGQTLSDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERARLAIKTFVHRIARHIAGHAASLHRLDGIIFTGGIGENSVLIRQLVIEHLGVLGLTLDVEMNKQPNSHGERIISANPSQVICAVIPTNEEKMIALDAIHLGNVKA 4g0q A 1.8 BS01 C5P A 1 Y691 K695 Q707 C708 K728 K732 Y98 K102 Q114 C115 K135 K139 ? 0003676 Kd=3mM -logKd/Ki=2.52, Kd=3.00mM O04379 22850669 801 SNKKMINGGTVNNWICINFSRQVQDNLARTFCQELAQMCYVSGMAFNPEPVLPPVSARPEQVEKVLKTRYHDATSKLSQGKEIDLLIVILPDNNGSLYGDLKRICETELGIVSQCCLTKHVFKMSKQYMANVALKINVKVGGRNTVL 4gtz A 3.191 BS01 C5P A 1 T238 F239 N259 L272 K277 Y322 Y353 D358 H517 T69 F70 N90 L103 K108 Y153 Y184 D189 H348 3.1.4.1,3.1.4.39,3.6.1.9 0003676,0005044,0006955,0016787,0030247,0046872 P06802,Q9R1E6 23027977 1009 KSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDPEDDDIYHMTVPYGRPRILLKQHRVCLLQQQQFLTGYSLDLLMPLWASYTFLSNDSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNHIYSEALLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFS 4gtz B 3.191 BS01 C5P B 1 T238 F239 N259 L272 F303 Y322 Y353 D358 H406 H517 T69 F70 N90 L103 F134 Y153 Y184 D189 H237 H345 3.1.4.1,3.1.4.39,3.6.1.9 0003676,0005044,0006955,0016787,0030247,0046872 P06802,Q9R1E6 23027977 1005 KSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDPDDDIYHMTVPYGRPRILLKQHRVCLLQQQQFLTGYSLDLLMPLWASYTFLSNDNCLYQDLRIPLSPVHKCSYYKLSYGFLTPPRLNHIYSEALLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFS 4hi5 A 3.6 BS01 C5P A 1 Q36 A37 H112 Q29 A30 H105 ? 0016020,0020002,0030430,0039660,0042802,0044423 P0C794 201 SKHSYVELKDKVIVPGWPTLMLEIDFVNQALNIPFLSVKEPLQLPREKKLTDYFTIDVEPAGHSLVNIYFQIDDFLLLTLNSLSVYKDPIRKYMFLRLNKEQSKHAINAAFNVFSYRLRNIGVGPLGPDIRSSGP 4hiu A 3.3 BS01 C5P A 1 Q36 F37 H112 Q28 F29 H104 ? 0016020,0020002,0030430,0039660,0042802,0044423 P0C794 300 KHSYVELKDKVIVPGWPTLMLEIDFVNQFLNIPFLSVKEPLQLPAEKKLTDYFTIDVEPAGHSLVNIYFQIDDFLLLTLNSLSVYKDPIRKYMFLRLNKEQSKHAINAAFNVFSYRLRNIGVGPLGPDIRSS 4jem A 1.553 BS01 C5P A 1 G19 G20 F22 R23 A58 E62 F68 D78 S97 G99 T100 E103 G8 G9 F11 R12 A47 E51 F57 D67 S86 G88 T89 E92 ? 0016787 B4Y381 23659472 201 AVGSVFLGGPFRQLVDPRTGVMSSGDQNVFSRLIEHFESRGTTVYNAHRREAWGAEFLSPAEATRLDHDEIKAADVFVAFPGVPASPGTHVEIGWASGMGKPMVLLLERDEDYAFLVTGLESQANVEILRFSGTEEIVERLDGAVARVLGRAGEPTV 4jem B 1.553 BS01 C5P B 1 G19 G20 F22 R23 A58 E62 D78 S97 G99 T100 E103 G10 G11 F13 R14 A49 E53 D69 S88 G90 T91 E94 ? 0016787 B4Y381 23659472 201 APAVGSVFLGGPFRQLVDPRTGVMSSGDQNVFSRLIEHFESRGTTVYNAHRREAWGAEFLSPAEATRLDHDEIKAADVFVAFPGVPASPGTHVEIGWASGMGKPMVLLLERDEDYAFLVTGLESQANVEILRFSGTEEIVERLDGAVARVLGR 4lmc A 1.742 BS01 C5P A 1 F57 P61 Y62 S64 F66 R122 Y124 Y126 R164 A171 E189 F2 P6 Y7 S9 F11 R64 Y66 Y68 R106 A113 E131 ? 0003723,0019013 P33469 24564608 200 EFNVVPYYSWFSGITQFQKGKEFEFVEGQGVPIAPGVPATEAKGYWYRHNRRSFKTADGQLLPRWYFYYLGTGPHAKDQYGTDIDGVYWVASNQADVNTPADIVDRDPSSDEAIPTRFPPGTVLPQGYYIEG 4o6m B 1.901 BS03 C5P B 1 K136 R157 P174 N175 T178 D217 G218 R222 E227 G231 A232 K136 R157 P174 N175 T178 D217 G218 R222 E227 G231 A232 ? 0000166,0008654,0016020,0016740,0016780,0046872 O27985 24923293 422 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIKAKRTGLKPAYYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRS 4o7y A 2.0 BS01 C5P A 1 E89 R93 G98 S99 D173 K175 T196 C197 R198 R214 E79 R83 G88 S89 D163 K165 T186 C187 R188 R204 6.3.2.6 0004639,0005524,0006164,0006189,0009236,0016874 O57978 301 KAKKMIPIDDDKLIMEFKDDATAFDGTKKARFKGKGWLNAQLSVIFFKLLEEHGIKTHFIGVAGGNRLIVEKLDMYPLEVVVRNVVAGSLKKRLPLPEGYELPEPIVELYYKNDELHDPMINYYHAKVLGISLDEIKKIEEIALKVNEILKDYLAKKGIILVDFKLEFGKDKNGDIVLADEISPDTCRFWDAKTKRSLDKDVFRFDKGDLIEAYKEIYERITGEKPEF 4o86 A 2.2 BS02 C5P A 1 E89 R93 S99 D173 K175 T196 C197 R198 E78 R82 S88 D162 K164 T185 C186 R187 6.3.2.6 0004639,0005524,0006164,0006189,0009236,0016874 O57978 503 AKKMIPIDDDKLIMEFKDDATAFDGTKKARFKGKGWLNAQLSVIFFKLLEEHGIKTHFIGVAGGNRLIVEKLDMYPLEVVVRNVVAGSLKKRLPLPEGYELPEPIVELYYKNDELHDPMINYYHAKVLGISLDEIKKIEEIALKVNEILKDYLAKKGIILVDFKLEFGKDKNGDIVLADEISPDTCRFWDAKTKRSLDKDVFRFDKGDLIEAYKEIYERITGEKPEF 4xsv A 2.7 BS01 C5P A 1 G220 A221 F222 H229 F232 H307 G308 T310 S336 L340 G174 A175 F176 H183 F186 H261 G262 T264 S290 L294 H65 G67 H47 G49 2.7.7.14 0003824,0004306,0006646,0009058 Q99447 401 GRRAVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTVDGRDTYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVDFLEKVHRLAERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYAVTAELLSHFKVDLVCHGKTEIIPDRDGSDPYQEPKRRGIFRQIDSGSNLTTDLIVQRIITN 4zcp A 1.98 BS01 C5P A 1 G624 V625 Y626 H630 G632 H633 Q636 D710 R755 T756 G9 V10 Y11 H15 G17 H18 Q21 D95 R114 T115 F662 G664 F47 G49 2.7.7.15 0003824,0004105,0006657,0009058 Q8IEE9 30046154 801 KNVVIYADGVYDMLHLGHMKQLEQAKKLFENTTLIVGVTSDNETKLFKGQVVQTLEERTETLKHIRWVDEIISPCPWVVTPEFLEKYKIDYVAHDDIDIYAWLKRAGKFKATQRTEGVSTTDLIVRILK 4zu0 A 1.8 BS01 C5P A 1 Y70 I71 E85 G109 N110 Y111 E112 I155 R163 Y70 I71 E85 G109 N110 Y111 E112 I155 R163 I71 E160 R163 I71 E160 R163 3.2.2.22 0000166,0016787,0017148,0030598,0035821,0090729 D9J2T9 29124196 304 DVSFRLSGADPSSYGMFIKDLRNALPHTEKVYNIPLLLPSVSGAGRYLLMHLFNYDGNTITVAVDVTNVYIMGYLALTTSYFFNEPAADLASQYVFRSARRKITLPYSGNYERLQIAAGKPREKIPIGLPALDTAISTLLHYDSTAAAGALLVLIQTTAEAARFKYIEQQIQERAYRDEVPSSATISLENSWSGLSKQIQLAQGNNGVFRTPTVLVDSKGNRVQITNVTSNVVTSNIQLLLNTKNI 5a0v B 2.8 BS04 C5P B 1 I30 T207 S341 I343 P344 H373 S375 H377 H404 I29 T206 S340 I342 P343 H372 S374 H376 H403 3.1.-.- 0003723,0004519,0004521,0004527,0004534,0005737,0006364,0006396,0008270,0046872 O86842 26253740 1458 SHPHPELGRPPALPKGGLRVTPLGGLGEIGRNMTVFEYGGRLLIVDCGVLFPEEEQPGIDLILPDFTSIRDRLDDIEGIVLTHGHEDHIGGVPFLLREKPDIPLIGSKLTLALIEAKLQEHRIRPYTLEVAEGHRERVGPFDCEFVAVNHSIPDALAVAIRTPAGMVVHTGDFKMDQLPLDGRLTDLHAFARLSEEGIDLLLADSTNAEVPGFVPPERDISNVLRQVFANARKRIIVASFASHVHRIQQILDAAHEYGRRVAFVGRSMVRNMGIARDLGYLKVPPGLVVDVKTLDDLPDSEVVLVCTGSQGEPMAALSRMANRDHQIRIVNGDTVILASSLIPGNENAVYRVINGLTRWGANVVHKGNAKVHVSGHASAGELLYFYNICRPKNLMPVHGEWRHLRANAELGALTGVPHDRIVIAEDGVVVDLVEGKAKITGKVQAGYVYVD 5b6d A 1.65 BS01 C5P A 1 R31 C155 R175 N177 D178 D186 H216 Y218 R27 C151 R171 N173 D174 D182 H212 Y214 E68 E64 ? 0004799,0005829,0006231,0008168,0016741,0032259 B4Y380 28000775 401 TFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAYGPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDARWAERVLDAGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFG 5b6d A 1.65 BS02 C5P B 1 K133 R134 K129 R130 E68 E64 ? 0004799,0005829,0006231,0008168,0016741,0032259 B4Y380 28000775 401 TFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAYGPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDARWAERVLDAGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFG 5b6d B 1.65 BS01 C5P A 1 K133 R134 K129 R130 E68 E64 ? 0004799,0005829,0006231,0008168,0016741,0032259 B4Y380 28000775 401 TFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAYGPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDARWAERVLDAPGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFG 5b6d B 1.65 BS02 C5P B 1 R31 C155 R175 N177 D178 D186 H216 Y218 R27 C151 R171 N173 D174 D182 H212 Y214 E68 E64 ? 0004799,0005829,0006231,0008168,0016741,0032259 B4Y380 28000775 401 TFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAYGPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDARWAERVLDAPGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFG 5b8f A 1.45 BS02 C5P A 1 A100 K104 M105 A106 A131 T132 T133 A102 K106 M107 A108 A133 T134 T135 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 P57708 202 HHMRIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGLIAEDLGVAVDQVNVKATTTERLGFTGREEGIAVHAVALLMAR 5b8f A 1.45 BS03 C5P C 1 D56 G58 D58 G60 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 P57708 202 HHMRIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGLIAEDLGVAVDQVNVKATTTERLGFTGREEGIAVHAVALLMAR 5b8f B 1.45 BS02 C5P B 1 M105 A106 A131 T132 T133 M106 A107 A132 T133 T134 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 P57708 202 HMRIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGLIAEDLGVAVDQVNVKATTTERLGFTGREEGIAVHAVALLMAR 5b8f C 1.45 BS02 C5P C 1 A100 K104 M105 A106 A131 T132 T133 A107 K111 M112 A113 A138 T139 T140 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 P57708 202 AHHHHHHMRIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGLIAEDLGVAVDQVNVKATTTERLGFTGREEGIAVHAVALLMAR 5dv2 A 2.07 BS01 C5P A 1 H360 P365 D410 N412 N480 F485 H530 H177 P182 D215 N217 N274 F279 H324 3.1.13.4 0003824,0004535 ic50=1250uM -logKd/Ki=2.90, IC50=1250uM Q96LI5 27013054 601 LPPRPWITLKERDSASFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEIVNCDADIISLQEVETEQYFTLFLPALKERGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMANSDGSEAMLNRVMTKDNIGVAVVLEVHKELFKQLLIVANAHMHWDPEYSDVKLIQTMMFVSEVKNILEKASIPLVLCADLNSLPDSGVVEYLSNGGVADNHKDFKELRYNECLMNFSRITHGFQLKSAYENNLMPYTNYTFDFKGVIDYIFYSKTHMNVLGVLGPLDPQWLVENNITGCPHPHIPSDHFSLLTQLELHP 5ebe A 3.0 BS03 C5P A 1 D110 H114 N151 H152 H293 H295 V322 K323 D78 H82 N119 H120 H261 H263 V290 K291 3.1.4.-,3.6.1.15 0004767,0005515,0005576,0005615,0006685,0008081,0008270,0009143,0016787,0016887,0046872,0070062,0160049 Q92484 26783088 607 PPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAIMNLDNISYADCLKQLYIK 5ebe C 3.0 BS03 C5P C 1 H47 K66 D110 H152 H293 H295 K323 H15 K34 D78 H120 H261 H263 K291 3.1.4.-,3.6.1.15 0004767,0005515,0005576,0005615,0006685,0008081,0008270,0009143,0016787,0016887,0046872,0070062,0160049 Q92484 26783088 607 PPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAIMNLDNISYADCLKQL 5fa1 A 2.1 BS01 C5P A 1 R163 L227 R263 A264 H265 P266 S285 S300 S301 V302 R163 L223 R259 A260 H261 P262 S281 S296 S297 V298 ? 0000271,0015774 Q6U8B0 27199480 501 GLAVFLPPYPFRGLKAPYLWMFYKYLHCATDSILFITGEDYLSVTDDEAQRARWEFDPASMASLGYELPNAQSMACHEYLTLDNAFYETLLSRHHHDPIKSFSAFLTERIPDLETELHALLDSKKGIIDQIDTFISICNCPSLEHVARTLGKEVMHIEIGPLRAPMYRNTAYLDFAGVNGGTEASARYEKCQAEFDIKASLGDLHNYFLEVLPPAHSAAGVVLQVEDDSNLIAYNHDFTNISLLSYVRQRYEKEDILVRAHPGSLFRLRDDVFTIDDSANSLAFINQCNEVFTINSSVGLEAILTGKKTTVLGDCSYAFINELAGASATVNAAAFYLFSYLVPFDLVFNQEYLKFRLGHPEEREIVGKHIEFYSADHSLSSLINEAISLE 5fa1 B 2.1 BS01 C5P B 1 R163 L227 R263 A264 H265 P266 S285 S300 S301 V302 R163 L227 R263 A264 H265 P266 S285 S300 S301 V302 ? 0000271,0015774 Q6U8B0 27199480 501 GLAVFLPPYPFRGLKAPYLWMFYKYLHCATDSILFITGEDYLSVTDDEAQRARWEFDPASMASLGYELPNAQSMACHEYLTLDNAFYETLLSRHHHDPIKSFSAFLTERIPDLETELHALLDSKKGIIDQIDTFISICNCPSLEHVARTLGKEVMHIEIGPLRAPMYRNTAYLDFAGVNGGTEASARYEKCQAEFDIKASLGDLHNYFLEVLPPAEAATHSAAGVVLQVEDDSNLIAYNHDFTNISLLSYVRQRYEKEDILVRAHPGSLFRLRDDVFTIDDSANSLAFINQCNEVFTINSSVGLEAILTGKKTTVLGDCSYAFINELAGASATVNAAAFYLFSYLVPFDLVFNQEYLKFRLGHPEEREIVGKHIEFYSASLSSLINEAIS 5h5k A 2.3 BS02 C5P A 1 D9 F64 R90 S94 T95 Y98 D9 F64 R90 S94 T95 Y98 2.7.4.9 0004798,0005524,0005737,0005829,0006227,0006233,0006235,0009165,0016301,0016310,0046940 O67099 28627020 206 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVL 5h5k B 2.3 BS02 C5P B 1 D9 R47 F64 R90 S94 Y98 D9 R47 F64 R90 S94 Y98 2.7.4.9 0004798,0005524,0005737,0005829,0006227,0006233,0006235,0009165,0016301,0016310,0046940 O67099 28627020 203 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVL 5iwy A 1.99 BS02 C5P A 1 A101 K105 M106 L107 A132 T133 T134 E136 A101 K105 M106 L107 A132 T133 T134 E136 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q06756 29335298 202 MFRIGQGFDVHQLVEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAVGEGDIGKHFPDTDPEFKDADSFKLLQHVWGIVKQKGYVLGNIDCTIIAQKPKMLPYIEDMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQATVLIQKG 5iwy A 1.99 BS03 C5P B 1 D57 G59 D57 G59 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q06756 29335298 201 MFRIGQGFDVHQLVEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAVGEGDIGKHFPDTDPEFKDADSFKLLQHVWGIVKQKGYVLGNIDCTIIAQKPKMLPYIEDMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQATVLIQKG 5iwy B 1.99 BS01 C5P B 1 K105 M106 L107 A132 T133 T134 K105 M106 L107 A132 T133 T134 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q06756 29335298 201 MFRIGQGFDVHQLVEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAVGEGDIGKHFPDTDPEFKDADSFKLLQHVWGIVKQKGYVLGNIDCTIIAQKPKMLPYIEDMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQATVLIQKG 5iwy B 1.99 BS03 C5P C 1 D57 G59 D57 G59 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q06756 29335298 201 MFRIGQGFDVHQLVEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAVGEGDIGKHFPDTDPEFKDADSFKLLQHVWGIVKQKGYVLGNIDCTIIAQKPKMLPYIEDMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQATVLIQKG 5iwy C 1.99 BS01 C5P A 1 D57 G59 D57 G59 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q06756 29335298 202 MFRIGQGFDVHQLVEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAVGEGDIGKHFPDTDPEFKDADSFKLLQHVWGIVKQKGYVLGNIDCTIIAQKPKMLPYIEDMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQATVLIQKG 5iwy C 1.99 BS02 C5P C 1 K105 M106 L107 A132 T133 T134 K105 M106 L107 A132 T133 T134 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q06756 29335298 201 MFRIGQGFDVHQLVEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAVGEGDIGKHFPDTDPEFKDADSFKLLQHVWGIVKQKGYVLGNIDCTIIAQKPKMLPYIEDMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQATVLIQKG 5iwy F 1.99 BS01 C5P F 1 A101 P104 K105 M106 L107 A132 T133 T134 A101 P104 K105 M106 L107 A132 T133 T134 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q06756 29335298 201 MFRIGQGFDVHQLVEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAVGEGDIGKHFPDTDPEFKDADSFKLLQHVWGIVKQKGYVLGNIDCTIIAQKPKMLPYIEDMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQATVLIQKG 5km2 A 1.25 BS01 C5P A 1 D43 I44 N99 S107 H112 H114 D32 I33 N88 S96 H101 H103 3.4.22.-,3.9.1.- 0000118,0000166,0003824,0005080,0005515,0005634,0005654,0005737,0005829,0005856,0005886,0006355,0006508,0006915,0007165,0008234,0009154,0016787,0016926,0016929,0043530,0050850,0070062,0072332 -logKd/Ki=4.41, Kd=39.1uM P49773 28968488 201 RPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 5ukd A 1.9 BS02 C5P A 1 G38 L41 E63 I64 V65 G90 R93 R137 R148 G38 L41 E63 I64 V65 G90 R93 R137 R148 K19 R93 R131 R137 R148 K19 R93 R131 R137 R148 2.7.4.14 0000287,0004127,0005524,0005634,0005737,0006139,0006207,0006221,0006225,0009041,0016301,0016310,0016776,0019205,0033862,0036430,0036431,0043100,0043173,0046705,0046940,0072528 P20425 10426946 196 MEKSKPNVVFVLGGPGSGKGTQCANIVRDFGWVHLSAGDLLRQEQQSGSKDGEMIATMIKNGEIVPSIVTVKLLKNAIDANQGKNFLVDGFPRNEENNNSWEENMKDFVDTKFVLFFDCPEEVMTQRLLKRGESSGRSDDNIESIKKRFNTFNVQTKLVIDHYNKFDKVKIIPANRDVNEVYNDVENLFKSMGF 5x4k A 1.749 BS03 C5P A 1 H107 K406 S408 R410 G437 G438 G439 A444 G445 H109 K408 S410 R412 G439 G440 G441 A446 G447 ? 0003676,0004527,0046872 Q8TZE0 30053256 504 SHMDKEGFLNKVREAVDVVKLHIELGHTIRIISHRDADGITSAAILAKALGREGASFHISIVKQVSEDLLRELKDEDYKIFIFSALGSGSLSLIKEYLKEKTVIILDHHPPENVKLEEKHILVNPVQFGANSVRDLSGSGVTYFFARELNEKNRDLAYIAIVGAVGDMQENDGVFHGMNLDIIEDGKSLGILEVKKELRLFGRETRPLYQMLAYATNPEIPEVTGDERKAIEWLKNKGFNPEKKYWELSEEEKKKLHDFLIIHMIKHGAGKEDIDRLIGDVVISPLYPEGDPRHEAREFATLLNATGRLNLGNLGVAVCLGDEEAFRKALKMVEDYKREQIEARKWLLQNWNSEVWEGDHVYVLYVGKSIRDTLVGIAASMAINAGLADPEKPVIVFADTDEDPNLLKGSARTTERALAKGYNLGEALRKAAELVNGEGGGHAIAAGIRIPRARLAEFRKLIDKILGEQVS 5x4k A 1.749 BS04 C5P A 2 H32 H106 H107 D165 M166 N169 R410 H440 I442 A443 H34 H108 H109 D167 M168 N171 R412 H442 I444 A445 ? 0003676,0004527,0046872 Q8TZE0 30053256 505 SHMDKEGFLNKVREAVDVVKLHIELGHTIRIISHRDADGITSAAILAKALGREGASFHISIVKQVSEDLLRELKDEDYKIFIFSALGSGSLSLIKEYLKEKTVIILDHHPPENVKLEEKHILVNPVQFGANSVRDLSGSGVTYFFARELNEKNRDLAYIAIVGAVGDMQENDGVFHGMNLDIIEDGKSLGILEVKKELRLFGRETRPLYQMLAYATNPEIPEVTGDERKAIEWLKNKGFNPEKKYWELSEEEKKKLHDFLIIHMIKHGAGKEDIDRLIGDVVISPLYPEGDPRHEAREFATLLNATGRLNLGNLGVAVCLGDEEAFRKALKMVEDYKREQIEARKWLLQNWNSEVWEGDHVYVLYVGKSIRDTLVGIAASMAINAGLADPEKPVIVFADTDEDPNLLKGSARTTERALAKGYNLGEALRKAAELVNGEGGGHAIAAGIRIPRARLAEFRKLIDKILGEQVS 5x4k A 1.749 BS05 C5P A 3 T214 Q338 I375 S378 T216 Q340 I377 S380 ? 0003676,0004527,0046872 Q8TZE0 30053256 506 SHMDKEGFLNKVREAVDVVKLHIELGHTIRIISHRDADGITSAAILAKALGREGASFHISIVKQVSEDLLRELKDEDYKIFIFSALGSGSLSLIKEYLKEKTVIILDHHPPENVKLEEKHILVNPVQFGANSVRDLSGSGVTYFFARELNEKNRDLAYIAIVGAVGDMQENDGVFHGMNLDIIEDGKSLGILEVKKELRLFGRETRPLYQMLAYATNPEIPEVTGDERKAIEWLKNKGFNPEKKYWELSEEEKKKLHDFLIIHMIKHGAGKEDIDRLIGDVVISPLYPEGDPRHEAREFATLLNATGRLNLGNLGVAVCLGDEEAFRKALKMVEDYKREQIEARKWLLQNWNSEVWEGDHVYVLYVGKSIRDTLVGIAASMAINAGLADPEKPVIVFADTDEDPNLLKGSARTTERALAKGYNLGEALRKAAELVNGEGGGHAIAAGIRIPRARLAEFRKLIDKILGEQVS 5zrh A 1.54 BS01 C5P A 1 V6 R22 E33 L34 L73 L79 D116 V4 R20 E31 L32 L71 L77 D114 3.6.1.55 0000166,0006260,0006281,0008413,0016787,0035539,0044715,0044716,0046872 A0R2K6 30312643 202 KQIVVAGALISRGTLLVAQRDRPAELAGLWELPGGKVTPGESDADALARELREELGVDVAVGERLGADVALNDAMTLRAYRVTLRSGSPHPHDHRALRWVGADEIDGLAWVPADRAWVPDLVAALSG 6apl A 2.35 BS01 C5P A 1 N156 G157 L178 N179 S304 G306 F325 I326 D335 H336 N86 G87 L108 N109 S228 G230 F249 I250 D259 H260 M302 H351 M226 H271 2.4.3.3 0000139,0001665,0005794,0006486,0006493,0008373,0016020,0016266,0016757,0019082,1990743 Q9UJ37 29251719 401 CRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLILYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPANHDLSLEAALWRDLHKAGILQLYQR 6apl B 2.35 BS01 C5P B 1 N156 G157 L178 N179 G180 S304 G306 F325 I326 D335 H336 N87 G88 L109 N110 G111 S233 G235 F254 I255 D264 H265 M302 H351 M231 H277 2.4.3.3 0000139,0001665,0005794,0006486,0006493,0008373,0016020,0016266,0016757,0019082,1990743 Q9UJ37 29251719 401 CRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPYANHDLSLEAALWRDLHKAGILQLYQR 6apl C 2.35 BS01 C5P C 1 N156 G157 L178 N179 S304 G306 F325 I326 D335 H336 L345 N88 G89 L110 N111 S236 G238 F257 I258 D267 H268 L277 M302 H351 M234 H283 2.4.3.3 0000139,0001665,0005794,0006486,0006493,0008373,0016020,0016266,0016757,0019082,1990743 Q9UJ37 29251719 401 CRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLYQR 6apl D 2.35 BS01 C5P D 1 N156 G157 L178 N179 S304 G306 F325 I326 D335 H336 L345 N84 G85 L106 N107 S232 G234 F253 I254 D263 H264 L273 M302 H351 M230 H279 2.4.3.3 0000139,0001665,0005794,0006486,0006493,0008373,0016020,0016266,0016757,0019082,1990743 Q9UJ37 29251719 401 CRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLYQR 6apl E 2.35 BS01 C5P E 1 N156 G157 L178 N179 S304 G306 F325 I326 D335 H336 N82 G83 L104 N105 S226 G228 F247 I248 D257 H258 M302 H351 M224 H262 2.4.3.3 0000139,0001665,0005794,0006486,0006493,0008373,0016020,0016266,0016757,0019082,1990743 Q9UJ37 29251719 401 CRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFNHDLSLEAALWRDLHKAGILQLYQR 6apl F 2.35 BS01 C5P F 1 N156 G157 L178 N179 S304 G306 F325 I326 H336 N80 G81 L102 N103 S225 G227 F246 I247 H257 M302 H351 M223 H262 2.4.3.3 0000139,0001665,0005794,0006486,0006493,0008373,0016020,0016266,0016757,0019082,1990743 Q9UJ37 29251719 401 LHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFENHDLSLEAALWRDLHKAGILQLYQR 6ckl A 2.684 BS01 C5P A 1 L10 A11 R12 N22 R71 A80 Q104 T106 L10 A11 R12 N22 R71 A80 Q104 T106 2.7.7.43 0005737,0008781,0016779 P0A0Z8 31583886 701 MEKQNIAVILARQNSKGLPLKNLRKMNGISLLGHTINAAISSKCFDRIIVSTDGGLIAEEAKNFGVEVVLRPAELASDTASSISGVIHALETIGSNSGTVTLLQPTSPLRTGAHIREAFSLFDEKIKGSVVSACPMEHHPLKTLLQINNGEYAPMRHLSDLEQPRQQLPQAFRPNGAIYINDTASLIANNCFFIAPTKLYIMSHQDSIDIDTELDLQQAENILNH 6ckl B 2.684 BS03 C5P B 1 L10 A11 R12 N22 R71 A80 Q104 T106 L10 A11 R12 N22 R71 A80 Q104 T106 2.7.7.43 0005737,0008781,0016779 P0A0Z8 31583886 303 MEKQNIAVILARQNSKGLPLKNLRKMNGISLLGHTINAAISSKCFDRIIVSTDGGLIAEEAKNFGVEVVLRPAELASDTASSISGVIHALETIGSNSGTVTLLQPTSPLRTGAHIREAFSLFDEKIKGSVVSACPMEHHPLKTLLQINNGEYAPMRHLSDLEQPRQQLPQAFRPNGAIYINDTASLIANNCFFIAPTKLYIMSHQDSIDIDTELDLQQAENILNH 6ckl C 2.684 BS02 C5P C 1 L10 A11 R12 N22 R71 Q104 T106 L10 A11 R12 N22 R71 Q104 T106 2.7.7.43 0005737,0008781,0016779 P0A0Z8 31583886 302 MEKQNIAVILARQNSKGLPLKNLRKMNGISLLGHTINAAISSKCFDRIIVSTDGGLIAEEAKNFGVEVVLRPAELASDTASSISGVIHALETIGSNSGTVTLLQPTSPLRTGAHIREAFSLFDEKIKGSVVSACPMEHHPLKTLLQINNGEYAPMRHLSDLEQPRQQLPQAFRPNGAIYINDTASLIANNCFFIAPTKLYIMSHQDSIDIDTELDLQQAENILNH 6i1r A 2.8 BS01 C5P A 1 P38 E42 S79 Y82 L83 N86 N206 W209 P34 E38 S75 Y78 L79 N82 N202 W205 ? 0000139,0015165,0016020,0090481 -logKd/Ki=5.84, IC50=1.45uM B4FZ94 31133698 401 MQWYLVAALLTILTSSQGILTTLSQSNYDYATIPFLAELFKLSVSGFFLWKECRTSPSVRMTKEWRSVRLYVVPSVIYLIHNNVQFATLTYVDPSTYQIMGNLKIVTTGILFRLVLKRKLSNIQWMAIVLLAVGTTTSQVKGCGDSPCDSLFSAPLEGYLLGILSACLSALAGVYTEYLMKKNNDSLYWQNVQLYTFGVIFNMGWLIYGDFKAGFELGPWWQRLFNGYSITTWMVVFNLGSTGLLVSWLMKYSDNIVKVYSTSMAMLLTMVLSIYLFSVKATIQLFLGIIICIISLQMYFMPVHMLIEL 6i1r B 2.8 BS01 C5P B 1 P38 E42 S79 Y82 L83 N86 N206 W209 P35 E39 S76 Y79 L80 N83 N203 W206 ? 0000139,0015165,0016020,0090481 B4FZ94 31133698 401 MQWYLVAALLTILTSSQGILTTLSQSNNYDYATIPFLAELFKLSVSGFFLWKECRTSPSVRMTKEWRSVRLYVVPSVIYLIHNNVQFATLTYVDPSTYQIMGNLKIVTTGILFRLVLKRKLSNIQWMAIVLLAVGTTTSQVKGCGDSPCDSLFSAPLEGYLLGILSACLSALAGVYTEYLMKKNNDSLYWQNVQLYTFGVIFNMGWLIYGDFKAGFELGPWWQRLFNGYSITTWMVVFNLGSTGLLVSWLMKYSDNIVKVYSTSMAMLLTMVLSIYLFSVKATIQLFLGIIICIISLQMYFMPVHMLIEL 6kal A 2.6 BS02 C5P A 1 G344 G345 R352 I357 W359 D360 D364 Q437 Q482 G299 G300 R307 I312 W314 D315 D319 Q388 Q433 2.7.8.- 0000139,0001654,0001701,0001764,0002162,0003007,0003016,0005515,0005576,0005615,0005654,0005737,0005783,0005791,0005794,0005829,0005886,0006096,0006486,0006600,0006629,0006936,0006954,0007417,0007420,0007507,0007519,0007628,0008104,0009100,0009101,0009410,0010001,0010467,0014823,0016485,0016740,0016780,0017038,0019321,0019519,0030198,0030282,0035269,0035437,0036058,0036211,0038026,0042383,0042692,0042802,0043010,0043236,0043403,0043491,0046872,0050905,0051146,0051262,0051384,0051674,0060538,0060539,0061061,0061448,0071711,0072592,0097305,0097709,0098528,0098723 Q9H9S5 31949166 503 GPRVTVLVREFEAFDNAVPELVDSFLQQDPAQPVVVAADTLPYPPLALPRIPNVRLALLQPALDRPAAASRPETYVATEFVALVPDGARAEAPGLLERMVEALRAGSARLVAAPVATANPARCLALNVSLREWTARYGAAPAAPRCDALDGDAVVLLRARDLFNLSAPLARPVGTSLFLQTALRGWAVQLLDLTFAAARQPPLATAHARWKAEREGRARRAALLRALGIRLVSWEGGRLEWFGCNKETTRCFGTVVGDTPAYLYEERWTPPCCLRALRETARYVVGVLEAAGVRYWLEGGSLLGAARHGDIIPWDYDVDLGIYLEDVGNCEQLRGAEAGSVVDERGFVWEKAVEGDFFRVQYSESNHLHVDLWPFYPRNGVMTKDTWQDVEFPEHFLQPLVPLPFAGFVAQAPNNYRRFLELKFGPGVIENPQYPNPALLSLT 6kal B 2.6 BS02 C5P B 1 G344 G345 L348 R352 I357 W359 D364 Q437 V477 P481 Q482 Y483 P484 G298 G299 L302 R306 I311 W313 D318 Q391 V431 P435 Q436 Y437 P438 2.7.8.- 0000139,0001654,0001701,0001764,0002162,0003007,0003016,0005515,0005576,0005615,0005654,0005737,0005783,0005791,0005794,0005829,0005886,0006096,0006486,0006600,0006629,0006936,0006954,0007417,0007420,0007507,0007519,0007628,0008104,0009100,0009101,0009410,0010001,0010467,0014823,0016485,0016740,0016780,0017038,0019321,0019519,0030198,0030282,0035269,0035437,0036058,0036211,0038026,0042383,0042692,0042802,0043010,0043236,0043403,0043491,0046872,0050905,0051146,0051262,0051384,0051674,0060538,0060539,0061061,0061448,0071711,0072592,0097305,0097709,0098528,0098723 Q9H9S5 31949166 504 PRVTVLVREFEAFDNAVPELVDSFLQQDPAQPVVVAADTLPYPPLALPRIPNVRLALLQPALDRPAAASRPETYVATEFVALVPDGARAEAPGLLERMVEALRAGSARLVAAPVATANPARCLALNVSLREWTARYGAAPAAPRCDALDGDAVVLLRARDLFNLSAPLARPVGTSLFLQTALRGWAVQLLDLTFAAARQPPLATAHARWKAEREGRARRAALLRALGIRLVSWEGGRLEWFGCNKETTRCFGTVVGDTPAYLYEERWTPPCCLRALRETARYVVGVLEAAGVRYWLEGGSLLGAARHGDIIPWDYDVDLGIYLEDVGNCEQLRGAEAGSVVDERGFVWEKAVEGDFFRVQYSESNHLHVDLWPFYPRNGVMTKDTWLDHRQDVEFPEHFLQPLVPLPFAGFVAQAPNNYRRFLELKFGPGVIENPQYPNPALLSL 6kal C 2.6 BS02 C5P C 1 L348 R352 I357 W359 V477 Q482 L302 R306 I311 W313 V426 Q431 2.7.8.- 0000139,0001654,0001701,0001764,0002162,0003007,0003016,0005515,0005576,0005615,0005654,0005737,0005783,0005791,0005794,0005829,0005886,0006096,0006486,0006600,0006629,0006936,0006954,0007417,0007420,0007507,0007519,0007628,0008104,0009100,0009101,0009410,0010001,0010467,0014823,0016485,0016740,0016780,0017038,0019321,0019519,0030198,0030282,0035269,0035437,0036058,0036211,0038026,0042383,0042692,0042802,0043010,0043236,0043403,0043491,0046872,0050905,0051146,0051262,0051384,0051674,0060538,0060539,0061061,0061448,0071711,0072592,0097305,0097709,0098528,0098723 Q9H9S5 31949166 504 PRVTVLVREFEAFDNAVPELVDSFLQQDPAQPVVVAADTLPYPPLALPRIPNVRLALLQPALDRPAAASRPETYVATEFVALVPDGARAEAPGLLERMVEALRAGSARLVAAPVATANPARCLALNVSLREWTARYGAAPAAPRCDALDGDAVVLLRARDLFNLSAPLARPVGTSLFLQTALRGWAVQLLDLTFAAARQPPLATAHARWKAEREGRARRAALLRALGIRLVSWEGGRLEWFGCNKETTRCFGTVVGDTPAYLYEERWTPPCCLRALRETARYVVGVLEAAGVRYWLEGGSLLGAARHGDIIPWDYDVDLGIYLEDVGNCEQLRGAEAGSVVDERGFVWEKAVEGDFFRVQYSESNHLHVDLWPFYPRNGVMTKDTWDVEFPEHFLQPLVPLPFAGFVAQAPNNYRRFLELKFGPGVIENPQYPNPALLSLT 6kal D 2.6 BS02 C5P D 1 G345 L348 R352 I357 W359 D360 Q437 V477 P481 Q482 Y483 P484 G299 L302 R306 I311 W313 D314 Q389 V429 P433 Q434 Y435 P436 2.7.8.- 0000139,0001654,0001701,0001764,0002162,0003007,0003016,0005515,0005576,0005615,0005654,0005737,0005783,0005791,0005794,0005829,0005886,0006096,0006486,0006600,0006629,0006936,0006954,0007417,0007420,0007507,0007519,0007628,0008104,0009100,0009101,0009410,0010001,0010467,0014823,0016485,0016740,0016780,0017038,0019321,0019519,0030198,0030282,0035269,0035437,0036058,0036211,0038026,0042383,0042692,0042802,0043010,0043236,0043403,0043491,0046872,0050905,0051146,0051262,0051384,0051674,0060538,0060539,0061061,0061448,0071711,0072592,0097305,0097709,0098528,0098723 Q9H9S5 31949166 504 PRVTVLVREFEAFDNAVPELVDSFLQQDPAQPVVVAADTLPYPPLALPRIPNVRLALLQPALDRPAAASRPETYVATEFVALVPDGARAEAPGLLERMVEALRAGSARLVAAPVATANPARCLALNVSLREWTARYGAAPAAPRCDALDGDAVVLLRARDLFNLSAPLARPVGTSLFLQTALRGWAVQLLDLTFAAARQPPLATAHARWKAEREGRARRAALLRALGIRLVSWEGGRLEWFGCNKETTRCFGTVVGDTPAYLYEERWTPPCCLRALRETARYVVGVLEAAGVRYWLEGGSLLGAARHGDIIPWDYDVDLGIYLEDVGNCEQLRGAEAGSVVDERGFVWEKAGDFFRVQYSESNHLHVDLWPFYPRNGVMTKDTWLDHRQDVEFPEHFLQPLVPLPFAGFVAQAPNNYRRFLELKFGPGVIENPQYPNPALLSL 6mgb A 1.8 BS01 C5P A 1 K132 Y133 I154 D155 K192 H194 P195 P224 S239 Q240 M241 E244 K138 Y139 I160 D161 K198 H200 P201 P230 S245 Q246 M247 E250 ? 0000271,0015774 A0A179D1D1 31036922 403 HHHHHHMPVGVFSRQILKNVPHLEVFLEDSVVYKPKGPEGLSAVAGWGYKSTARKAMQKAREWRLPYLALEDGFLRSVGLGHEAPPLSLIVDPVGIYYDATRPSLLENLLNFGGWETPELMDQAERALKLIRDHKISKYNRGKPVPRGYFTPYRERVLLIDQTYGDMSVRLGLADEDTFREMYFAALEENPGAEIYVKVHPEVIVGRKKGYLARMKLHRSVKVIREEFNPVDLLSHFDRIYTVSSQMGFEGLMLGKEVICFGMPFYAGWGLTRDGKRCERRKRRRTLLELFAAAYLLYPRYINPATGKPGNIFDVINHLIG 6mgc A 1.35 BS01 C5P A 1 S132 K133 Y134 V154 D155 K192 H194 P195 P224 S239 Q240 Y241 E244 S132 K133 Y134 V150 D151 K188 H190 P191 P220 S235 Q236 Y237 E240 ? 0000271,0015774 A0A0H2Z2W8 31036922 401 GIGIYSPGIWRIPHLEKFLAQPCQKLSLLRPVPQEVNAIAVWGHRPSAAKPVAIAKAAGKPVIRLEDGFVRSLDLGVNGEPPLSLVVDDCGIYYDASKPSALEKLVQDKAGNTALISQAREAMHTIVTGDMSKYNLAPAFVADTNIVLVVDQTFNDMSVTYGNAGPHEFAAMLEAAMAENPQAEIWVKVHPDVLEGKKTGYFADLRATQRVRLIAENVSPQSLLRHVSRVYVVTSQYGFEALLAGKPVTCFGQPWYASWGLTDDRHPQSALLSARRGSATLEELFAAAYLRYCRYIDPQTGEVSDLFTVLQWLQLQRRH 6oh2 A 2.58 BS01 C5P A 1 K55 Y98 Q101 N102 Y121 K124 S188 F195 Y214 G257 S261 K272 K41 Y84 Q87 N88 Y107 K110 S170 F177 Y196 G239 S243 K254 ? 0000139,0005456,0005794,0015165,0015297,0015782,0016020,0090481 -logKd/Ki=5.20, Kd=6.3uM Q61420 30985278 401 YCLTVMTLVAAAYTVALRYTRTTAEELYFSTTAVCITEVIKLLISVGLLAKETGSLGRFKASLSENVLGSPKELAKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWISVFMLCGGVTLVQWKPAVVVAQNPLLGFGAIAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIVVTLAGTYLSDGAEIQEKGFFYGYTYYVWFVIFLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVLLFGLQITLSFALGALLVCVSIYLYGLPR 6oh4 A 3.38 BS01 C5P A 1 K55 Y98 Q101 N102 Y121 S188 F195 Y214 G257 S261 K272 K41 Y84 Q87 N88 Y107 S170 F177 Y196 G239 S243 K254 ? 0000139,0005456,0005794,0015165,0015297,0015782,0016020,0090481 Q61420 30985278 401 YCLTVMTLVAAAYTVALRYTRTTAEELYFSTTAVCITEVIKLLISVGLLAKETGSLGRFKASLSENVLGSPKELAKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWISVFMLCGGVTLVQWKPAVVVAQNPLLGFGAIAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIVVTLAGTYLSDGAEIQEKGFFYGYTYYVWFVIFLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVLLFGLQITLSFALGALLVCVSIYLYGLPR 6oh4 B 3.38 BS01 C5P B 1 K55 Y98 Q101 N102 Y121 K124 S188 F195 M213 Y214 G257 K272 K41 Y84 Q87 N88 Y107 K110 S170 F177 M195 Y196 G239 K254 ? 0000139,0005456,0005794,0015165,0015297,0015782,0016020,0090481 Q61420 30985278 401 YCLTVMTLVAAAYTVALRYTRTTAEELYFSTTAVCITEVIKLLISVGLLAKETGSLGRFKASLSENVLGSPKELAKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWISVFMLCGGVTLVQWKPAVVVAQNPLLGFGAIAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIVVTLAGTYLSDGAEIQEKGFFYGYTYYVWFVIFLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVLLFGLQITLSFALGALLVCVSIYLYGLPR 6wmv C 2.142 BS01 C5P C 1 D31 D71 G72 G85 D89 D157 D197 G198 G211 D215 ?,2.7.8.- 0008654,0016020,0016780 O27985,U5WZP7 32389689 301 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIAAFARITLPLARALLRIGLTPDAVTIIGTTASVAGALVLFPMGKLFPGACVVWFFVLFDMLDGAMARLRSGGTRFGAVLDAACDRISDGAVFSGLLWWIAFGMRDRLLVVATLTCLVTSQVISYIKARAEASGLRGDGGIIERPERLIIVLVGAGVSDFPFIAWPPALPVAMWVLAVASVITLGQRLHTVWTSPGATDRIP 7ckj A 1.5 BS01 C5P A 1 S11 K15 S33 G34 Y37 R38 V97 R107 G125 R126 S11 K15 S33 G34 Y37 R38 V97 R107 G125 R126 2.7.4.25 0004127,0005524,0005737,0005829,0006139,0006220,0009058,0015949,0016301,0016310,0036430,0036431,0044281,0046940 Q5SL35 32469932 301 MRGIVTIDGPSASGKSSVARRVAAALGVPYLSSGLLYRAAAFLALRAGVDPGDEEGLLALLEGLGVRLLAQAEGNRVLADGEDLTSFLHTPEVDRVVSAVARLPGVRAWVNRRLKEVPPPFVAEGRDMGTAVFPEAAHKFYLTASPEVRAWRRARERPQAYEEVLRDLLRRDERDQSAPAPDALVLDTGGMTLDEVVAWVLAHIRR 7k06 A 1.95 BS01 C5P A 1 E152 A153 C155 K157 Q159 L203 H307 E17 A18 C20 K22 Q24 L68 H172 3.1.-.- 0000175,0003676 O43414 501 MSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSK 7k06 B 1.95 BS01 C5P B 1 E152 A153 C155 L203 W248 H307 E17 A18 C20 L68 W113 H172 3.1.-.- 0000175,0003676 O43414 501 MSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSK 7qtb A 1.04 BS04 C5P A 1 F81 D83 H145 A151 N154 H168 F61 D63 H125 A131 N134 H148 3.1.30.1 0003676,0004518,0004519,0005575,0006308,0016788,0046872 P24021 36189740 407 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 7qtb B 1.04 BS04 C5P B 1 F81 D83 H145 A151 N154 H168 F61 D63 H125 A131 N134 H148 3.1.30.1 0003676,0004518,0004519,0005575,0006308,0016788,0046872 P24021 36189740 407 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIAS 8a0c B 2.9 BS04 C5P B 1 H96 R163 C195 P196 K231 V232 H233 Y265 S279 S280 H97 R164 C196 P197 K232 V233 H234 Y266 S280 S281 ? 0005886,0016020,0016740,0019350,0046872,0047355 Q2ERG0 37277468 1207 VDKTWLFGSYAWQGNPKALFLYMLVNCKETHECWWVADNEESMKSIKKSTGLKNITFTDSEKAKELFPHADVYVTENFRESYPVYMNENIKVFNTWHGVGLKHIELALGMNSVLAESIVRKYVRNYDIYKNNVLFLTTSQAMEDHFLEDMAISKELIIRGKYPRNAVYGPNGIHTYDINTLLPKNKSQYSQTILFCPTYRIGAIQGVLNSLLPDFAKLEEVCRHKNQLFIVKVHPFMKKDNYFAEMSEKYKDSEYILFWNDDYDIYEAFNSIDLAIIDYSSIFYDLLDAGVEKFIRYVPDLDEYQNDLELIGDYADLTEGRIVKSFQQLLNCLDNANIKIISTKRKQYLMDYFFGFKKENKSMESLIADVDNCQLQPKSLKELHTFDIFDTLIRRSTLRPFSIFDYVRDKAKASGIKFPLALTENWINVRNRAEHDVRDIMRKTTFERQSDKIEITLDDIYTRLQKNLLLTDEQTDFLKQAEIEAEIAHVEPIQKRINYLFSLKAKGHDVAMASDMYLPEDVIYKMLDRADTRLREIPLYLSSTIGYQKSTGKLYQHIFFDLDYQYSRWTHYGDNKHADGSVPRRLGIQTAVHDIDDFIPFENAMVNAMDNYNRYPAYQLATKMHRYRTQLVQENGFGNTLFETKYYNYAYVGASFVPYINWAIKDAIKRGYETIYFISRDGHFLKQIADKIIEIRGYNVKTKYIYGSRKAWRLPSFITKVDDETFWQFGNFVGMDSFEDLVKASYLSESELLSLFPEFESLRHAKHLRGEIAENIRKIFKNSPAYHEKVLAIAAEKRKMVRQYIQQEINPKEKFAFVEFWGRGYTQDTFGRLLNDAFGKEVKNPFYYVRSFTDDMGTSVRHNFILAPQNFSFFEPIFAQTPYDSIPDYYEEKGRIEPIINHRDRSVSDLISEGLLKFTEDYLALNTQDEDYFDAALSQFNYQYQLNTPNDQFICNVFSELKDNIGVEKPYAPALTLKQLESITSKQELDKLTQSIPISLSKSDVKVIDYYNKIQKNYNLPAYNSTPMRKAYAVNPLEQYVWSTQVPFRVLSLKQNSFYLDVSFAETTKRKDIFLKELNEIDVIAVDWLKGGVPRLLTEHGYITAHKDWVKKS 8csb A 2.25 BS01 C5P A 1 R163 L227 R263 H265 S285 S300 S301 V302 R163 L227 R263 H265 S285 S300 S301 V302 ? 0000271,0015774 Q6U8B0 36271007 504 GLAVFLPPYPFRGLKAPYLWMFYKYLHCATDSILFITGEDYLSVTDDEAQRARWEFDPASMASLGYELPNAQSMACHEYLTLDNAFYETLLSRHHHDPIKSFSAFLTERIPDLETELHALLDSKKGIIDQIDTFISICNCPSLEHVARTLGKEVMHIEIGPLRAPMYRNTAYLDFAGVNGGTEASARYEKCQAEFDIKASLGDLHNYFLEVLPPAEAATHSAAGVVLQVEDNSNLIAYNHDFTNISLLSYVRQRYEKEDILVRAHPGSLFRLRDDVFTIDDSANSLAFINQCNEVFTINSSVGLEAILTGKKTTVLGDCSYAFINELAGASATVNAAAFYLFSYLVPFDLVFNQEYLKFRLGHPEEREIVGKHIEFYSAHSLSSLINEAISLEH 8csb B 2.25 BS02 C5P B 1 L227 R263 A264 H265 P266 S285 S300 S301 V302 L227 R263 A264 H265 P266 S285 S300 S301 V302 ? 0000271,0015774 Q6U8B0 36271007 503 GLAVFLPPYPFRGLKAPYLWMFYKYLHCATDSILFITGEDYLSVTDDEAQRARWEFDPASMASLGYELPNAQSMACHEYLTLDNAFYETLLSRHHHDPIKSFSAFLTERIPDLETELHALLDSKKGIIDQIDTFISICNCPSLEHVARTLGKEVMHIEIGPLRAPMYRNTAYLDFAGVNGGTEASARYEKCQAEFDIKASLGDLHNYFLEVLPPAEAATHSAAGVVLQVEDNSNLIAYNHDFTNISLLSYVRQRYEKEDILVRAHPGSLFRLRDDVFTIDDSANSLAFINQCNEVFTINSSVGLEAILTGKKTTVLGDCSYAFINELAGASATVNAAAFYLFSYLVPFDLVFNQEYLKFRLGHPEEREIVGKHIEFYSAHSLSSLINEAIS 8csc A 1.9 BS01 C5P A 1 R163 L227 R263 H265 P266 S285 S300 S301 V302 R163 L225 R261 H263 P264 S283 S298 S299 V300 ? 0000271,0015774 Q6U8B0 36271007 501 GLAVFLPPYPFRGLKAPYLWMFYKYLHCATDSILFITGEDYLSVTDDEAQRARWEFDPASMASLGYELPNAQSMACHEYLTLDNAFYETLLSRHHHDPIKSFSAFLTERIPDLETELHALLDSKKGIIDQIDTFISICNCPSLEHVARTLGKEVMHIEIGPLRAPMYRNTAYLDFAGVNGGTEASARYEKCQAEFDIKASLGDLHNYFLEVLPPAETHSAAGVVLQVEDNSNLIAYNHDFTNISLLSYVRQRYEKEDILVRAHPGSLFRLRDDVFTIDDSANSLAFINQCNEVFTINSSVGLEAILTGKKTTVLGDCSYAFINELAGASATVNAAAFYLFSYLVPFDLVFNQEYLKFRLGHPEEREIVGKHIEFYSADHSLSSLINEAISLEHH 8csc B 1.9 BS01 C5P B 1 R163 L227 R263 A264 H265 P266 S285 S300 S301 V302 R163 L227 R263 A264 H265 P266 S285 S300 S301 V302 ? 0000271,0015774 Q6U8B0 36271007 501 GLAVFLPPYPFRGLKAPYLWMFYKYLHCATDSILFITGEDYLSVTDDEAQRARWEFDPASMASLGYELPNAQSMACHEYLTLDNAFYETLLSRHHHDPIKSFSAFLTERIPDLETELHALLDSKKGIIDQIDTFISICNCPSLEHVARTLGKEVMHIEIGPLRAPMYRNTAYLDFAGVNGGTEASARYEKCQAEFDIKASLGDLHNYFLEVLPPAEAATHSAAGVVLQVEDNSNLIAYNHDFTNISLLSYVRQRYEKEDILVRAHPGSLFRLRDDVFTIDDSANSLAFINQCNEVFTINSSVGLEAILTGKKTTVLGDCSYAFINELAGASATVNAAAFYLFSYLVPFDLVFNQEYLKFRLGHPEEREIVGKHIEFYSADSLSSLINEAISLE 8csd A 1.95 BS01 C5P A 1 R163 L227 R263 A264 H265 P266 S285 S300 S301 V302 R163 L225 R261 A262 H263 P264 S283 S298 S299 V300 ? 0000271,0015774 Q6U8B0 36271007 501 GLAVFLPPYPFRGLKAPYLWMFYKYLHCATDSILFITGEDYLSVTDDEAQRARWEFDPASMASLGYELPNAQSMACHEYLTLDNAFYETLLSRHHHDPIKSFSAFLTERIPDLETELHALLDSKKGIIDQIDTFISICNCPSLEHVARTLGKEVMHIEIGPLRAPMYRNTAYLDFAGVNGGTEASARYEKCQAEFDIKASLGDLHNYFLEVLPPAETHSAAGVVLQVEDCSNLIAYNHDFTNISLLSYVRQRYEKEDILVRAHPGSLFRLRDDVFTIDDSANSLAFINQCNEVFTINSSVGLEAILTGKKTTVLGDCSYAFINELAGASATVNAAAFYLFSYLVPFDLVFNQEYLKFRLGHPEEREIVGKHIEFYSADMPHSLSSLINEAISLEHHH 8csd B 1.95 BS01 C5P B 1 R163 L227 R263 H265 P266 S285 S300 S301 V302 R163 L227 R263 H265 P266 S285 S300 S301 V302 ? 0000271,0015774 Q6U8B0 36271007 501 GLAVFLPPYPFRGLKAPYLWMFYKYLHCATDSILFITGEDYLSVTDDEAQRARWEFDPASMASLGYELPNAQSMACHEYLTLDNAFYETLLSRHHHDPIKSFSAFLTERIPDLETELHALLDSKKGIIDQIDTFISICNCPSLEHVARTLGKEVMHIEIGPLRAPMYRNTAYLDFAGVNGGTEASARYEKCQAEFDIKASLGDLHNYFLEVLPPAEAATHSAAGVVLQVEDCSNLIAYNHDFTNISLLSYVRQRYEKEDILVRAHPGSLFRLRDDVFTIDDSANSLAFINQCNEVFTINSSVGLEAILTGKKTTVLGDCSYAFINELAGASATVNAAAFYLFSYLVPFDLVFNQEYLKFRLGHPEEREIVGKHIEFYSAHSLSSLINEAISLE 8cse A 2.3 BS03 C5P A 1 R163 L227 R263 A264 H265 P266 S285 S300 S301 V302 R163 L225 R261 A262 H263 P264 S283 S298 S299 V300 ? 0000271,0015774 Q6U8B0 36271007 502 GLAVFLPPYPFRGLKAPYLWMFYKYLHCATDSILFITGEDYLSVTDDEAQRARWEFDPASMASLGYELPNAQSMACHEYLTLDNAFYETLLSRHHHDPIKSFSAFLTERIPDLETELHALLDSKKGIIDQIDTFISICNCPSLEHVARTLGKEVMHIEIGPLRAPMYRNTAYLDFAGVNGGTEASARYEKCQAEFDIKASLGDLHNYFLEVLPPAEAHSAAGVVLQVEDDSNLIAYNHDFTNISLLSYVRQRYEKEDILVRAHPGSLFRLRDDVFTIDDSANSLAFINQCNEVFTINSSVGLEAILTGKKTTVLGDCSYAFINELAGASATVNAAAFYLFSYLVPFDLVFNQEYLKFRLGHPEEREIVGKHIEFYSADMSSLSSLINEAISLEHH 8cse B 2.3 BS02 C5P B 1 R163 L227 R263 A264 H265 P266 S285 S300 S301 V302 R163 L227 R263 A264 H265 P266 S285 S300 S301 V302 ? 0000271,0015774 Q6U8B0 36271007 501 GLAVFLPPYPFRGLKAPYLWMFYKYLHCATDSILFITGEDYLSVTDDEAQRARWEFDPASMASLGYELPNAQSMACHEYLTLDNAFYETLLSRHHHDPIKSFSAFLTERIPDLETELHALLDSKKGIIDQIDTFISICNCPSLEHVARTLGKEVMHIEIGPLRAPMYRNTAYLDFAGVNGGTEASARYEKCQAEFDIKASLGDLHNYFLEVLPPAEAATHSAAGVVLQVEDDSNLIAYNHDFTNISLLSYVRQRYEKEDILVRAHPGSLFRLRDDVFTIDDSANSLAFINQCNEVFTINSSVGLEAILTGKKTTVLGDCSYAFINELAGASATVNAAAFYLFSYLVPFDLVFNQEYLKFRLGHPEEREIVGKHIEFYSADSSLSSLINEAISLEHH 8csf A 2.4 BS02 C5P A 1 R163 L227 R263 A264 H265 P266 S285 S300 S301 V302 R161 L225 R261 A262 H263 P264 S283 S298 S299 V300 ? 0000271,0015774 Q6U8B0 36271007 501 GLAVFLPPYPFRGLKAPYLWMFYKYLHCATDSILFITGEDYLSVTDAQRARWEFDPASMASLGYELPNAQSMACHEYLTLDNAFYETLLSRHHHDPIKSFSAFLTERIPDLETELHALLDSKKGIIDQIDTFISICNCPSLEHVARTLGKEVMHIEIGPLRAPMYRNTAYLDFAGVNGGTEASARYEKCQAEFDIKASLGDLHNYFLEVLPPAEAATHSAAGVVLQVEDCSNLIAYNHDFTNISLLSYVRQRYEKEDILVRAHPGSLFRLRDDVFTIDDSANSLAFINQCNEVFTINSSVGLEAILTGKKTTVLGDCSYAFINELAGASATVNAAAFYLFSYLVPFDLVFNQEYLKFRLGHPEEREIVGKHIEFYSASLSSLINEAISLE 8csf B 2.4 BS02 C5P B 1 R163 V226 L227 R263 A264 H265 P266 S285 S300 S301 V302 R161 V221 L222 R258 A259 H260 P261 S280 S295 S296 V297 ? 0000271,0015774 Q6U8B0 36271007 501 GLAVFLPPYPFRGLKAPYLWMFYKYLHCATDSILFITGEDYLSVTDAQRARWEFDPASMASLGYELPNAQSMACHEYLTLDNAFYETLLSRHHHDPIKSFSAFLTERIPDLETELHALLDSKKGIIDQIDTFISICNCPSLEHVARTLGKEVMHIEIGPLRAPMYRNTAYLDFAGVNGGTEASARYEKCQAEFDIKASLGDLHNYFLEVLPPAEHSAAGVVLQVEDCSNLIAYNHDFTNISLLSYVRQRYEKEDILVRAHPGSLFRLRDDVFTIDDSANSLAFINQCNEVFTINSSVGLEAILTGKKTTVLGDCSYAFINELAGASATVNAAAFYLFSYLVPFDLVFNQEYLKFRLGHPEEREIVGKHIEFYSADHSLSSLINEAISLEHH 8fuw A 1.9 BS01 C5P A 1 S132 K133 Y134 V154 D155 K192 H194 P195 P224 S239 Q240 Y241 E244 S132 K133 Y134 V150 D151 K188 H190 P191 P220 S235 Q236 Y237 E240 ? 0000271,0015774 A0A0H2Z2W8 36924942 501 GIGIYSPGIWRIPHLEKFLAQPCQKLSLLRPVPQEVNAIAVWGHRPSAAKPVAIAKAAGKPVIRLEDGFVRSLDLGVNGEPPLSLVVDDCGIYYDASKPSALEKLVQDKAGNTALISQAREAMHTIVTGDMSKYNLAPAFVARTNIVLVVDQTFNNMSVTYGNAGPHEFAAMLEAAMAENPQAEIWVKVHPDVLEGKKTGYFADLRATQRVRLIAENVSPQSLLRHVSRVYVVTSQYGFEALLAGKPVTCFGQPWYASWGLTDDRHPQSALLSARRGSATLEELFAAAYLRYCRYIDPQTGEVSDLFTVLQWLQLQ 8fux A 1.2 BS03 C5P A 1 S132 K133 Y134 V154 D155 K192 H194 P195 P224 S239 Q240 Y241 E244 S132 K133 Y134 V152 D153 K190 H192 P193 P222 S237 Q238 Y239 E242 ? 0000271,0015774 A0A0H2Z2W8 36924942 403 GIGIYSPGIWRIPHLEKFLAQPCQKLSLLRPVPQEVNAIAVWGHRPSAAKPVAIAKAAGKPVIRLEDGFVRSLDLGVNGEPPLSLVVDDCGIYYDASKPSALEKLVQDKAGNTALISQAREAMHTIVTGDMSKYNLAPAFVADESTNIVLVVDQTFNCMSVTYGNAGPHEFAAMLEAAMAENPQAEIWVKVHPDVLEGKKTGYFADLRATQRVRLIAENVSPQSLLRHVSRVYVVTSQYGFEALLAGKPVTCFGQPWYASWGLTDDRHPQSALLSARRGSATLEELFAAAYLRYCRYIDPQTGEVSDLFTVLQWLQLQRRHH 8hce B 1.501 BS01 C5P B 1 E20 A21 G23 L24 Y129 E18 A19 G21 L22 Y127 3.1.11.2 0003676,0008408 Q91XB0 37870446 301 SQTLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASSKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGT 8qjm A 1.65 BS01 C5P A 1 W27 D71 R74 H88 D145 H151 D179 W1 D45 R48 H62 D119 H125 D153 301 WGAQGHRLVAEVADARLNPTARAEVDRLLATEPDATLASIAPWADQLRAKDPGLGRRSAGWHYVNIAEDNCHYEAPKHCRNGNCIVEALKAQSTILGDRSLTDGERLQALKFVVHLVGDIHQPMHAGYAHDKGGNDFQLQFGNRGTNLHSLWDSGMLNTRKLDDAGYLPLLQSQRAPKLARQSNPQRDPQTWAEASCRISMQAGVYPATRKIGDEYTERYRPLAEAQLRLAGENLAQLLNRVLGARLE 8qjm B 1.65 BS01 C5P B 1 W27 D71 R74 H88 D145 H151 D179 W1 D45 R48 H62 D119 H125 D153 301 WGAQGHRLVAEVADARLNPTARAEVDRLLATEPDATLASIAPWADQLRAKDPGLGRRSAGWHYVNIAEDNCHYEAPKHCRNGNCIVEALKAQSTILGDRSLTDGERLQALKFVVHLVGDIHQPMHAGYAHDKGGNDFQLQFGNRGTNLHSLWDSGMLNTRKLDDAGYLPLLQSQRAPKLARQSNPQRDPQTWAEASCRISMQAGVYPATRKIGDEYTERYRPLAEAQLRLAGENLAQLLNRVLGARLEH 8qjm B 1.65 BS02 C5P B 2 Y89 N91 K158 N161 H175 Y63 N65 K132 N135 H149 302 WGAQGHRLVAEVADARLNPTARAEVDRLLATEPDATLASIAPWADQLRAKDPGLGRRSAGWHYVNIAEDNCHYEAPKHCRNGNCIVEALKAQSTILGDRSLTDGERLQALKFVVHLVGDIHQPMHAGYAHDKGGNDFQLQFGNRGTNLHSLWDSGMLNTRKLDDAGYLPLLQSQRAPKLARQSNPQRDPQTWAEASCRISMQAGVYPATRKIGDEYTERYRPLAEAQLRLAGENLAQLLNRVLGARLEH 8qjq A 1.8 BS04 C5P A 1 W27 D71 R74 H88 D145 H151 W1 D45 R48 H62 D119 H125 404 WGAQGHRLVAEVADARLNPTARAEVDRLLATEPDATLASIAPWADQLRAKDPGLGRRSAGWHYVNIAEDNCHYEAPKHCRNGNCIVEALKAQSTILGDRSLTDGERLQALKFVVHLVGDIHQPMHAGYAHDKGGNDFQLQFGNRGTNLHSLWDSGMLNTRKLDDAGYLPLLQSQRAPKLARQSNPQRDPQTWAEASCRISMQAGVYPATRKIGDEYTERYRPLAEAQLRLAGENLAQLLNRVLGARLE 8qjq B 1.8 BS04 C5P B 1 Y89 N91 H151 K158 G159 N161 H175 Y63 N65 H125 K132 G133 N135 H149 404 WGAQGHRLVAEVADARLNPTARAEVDRLLATEPDATLASIAPWADQLRAKDPGLGRRSAGWHYVNIAEDNCHYEAPKHCRNGNCIVEALKAQSTILGDRSLTDGERLQALKFVVHLVGDIHQPMHAGYAHDKGGNDFQLQFGNRGTNLHSLWDSGMLNTRKLDDAGYLPLLQSQRAPKLARQSNPQRDPQTWAEASCRISMQAGVYPATRKIGDEYTERYRPLAEAQLRLAGENLAQLLNRVLGARLEHH 8sv2 A 1.84 BS01 C5P A 1 G267 K310 G311 H312 P313 S337 F338 E339 S356 S357 L358 G242 K285 G286 H287 P288 S312 F313 E314 S331 S332 L333 ? 0016757 Q15KI8 501 MKTITLYLDPASLPALNQLMDFTQNNEDKTHPRIFGLSRFKIPDNIITQYQNIHFVELKDNRPTEALFTILDQYPGNIELNIHLNIAHSVQLIRPILAYRFKHLDRVSIQQLNLYDNGSMEYVDLEKEENKDISAEIKQAEKQLSHYLLTGKIKFDNPTIARYVWQSAFPVKYHFLSTDYFEKAEFLQPLKEYLAENYQKMDWTAYQQLTPEQQAFYLTLVGFNDEVKQSLEVQQAKFIFTGTTTWEGNTDVREYYAQQQLNLLNHFTQAEGDLFIGDHYKIYFKGHPRGGEINDYILNNAKNITNIPANISFEVLMMTGLLPDKVGGVASSLYFSLPKEKISHIIFTSNKQVKSKDALNNPYVKVMRRLGIIDESQVIFWDSLKQL 8vqz A 2.05 BS01 C5P A 1 W152 G229 G230 H333 N336 E387 F389 W150 G227 G228 H331 N334 E385 F387 1.2.1.8 0000166,0008802,0016491,0016620,0019285,0046872 A0A0H3FPU4 501 RMAEQQLYIHGKFVAATSGKTFETINPATGEVLATVQAAGREDVDRAVKSAQQGQKVWAAMSAMARSRILRKAVDILRERNDELARLETLDTGKPLSETAAVDIVTGADVLEYYAGLIPALEGSQIPLRDSSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYREAGLPDGVFNVLPGIGAETGQYLTEHPDIAKISFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIIAEDANLDLAADIAMMANFYSSGQVCTNGTRVFVPAKFKAEFEHKILERVGRIRAGDLFADDTNFGPLVSFPHRQNVLRYIESGKSEGARLLCGGDVLKGEGFDNGAWVAPTVFTDCTDDMTIVREEIFGPVMSILSYDDEAEVIRRANATEYGLAAGVVTPDLNRAHRIIHQLEAGICWINSWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMGPFQSIF 8vqz B 2.05 BS01 C5P B 1 W152 G229 G230 H333 N336 E387 F389 W150 G227 G228 H331 N334 E385 F387 1.2.1.8 0000166,0008802,0016491,0016620,0019285,0046872 A0A0H3FPU4 501 RMAEQQLYIHGKFVAATSGKTFETINPATGEVLATVQAAGREDVDRAVKSAQQGQKVWAAMSAMARSRILRKAVDILRERNDELARLETLDTGKPLSETAAVDIVTGADVLEYYAGLIPALEGSQIPLRDSSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYREAGLPDGVFNVLPGIGAETGQYLTEHPDIAKISFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIIAEDANLDLAADIAMMANFYSSGQVCTNGTRVFVPAKFKAEFEHKILERVGRIRAGDLFADDTNFGPLVSFPHRQNVLRYIESGKSEGARLLCGGDVLKGEGFDNGAWVAPTVFTDCTDDMTIVREEIFGPVMSILSYDDEAEVIRRANATEYGLAAGVVTPDLNRAHRIIHQLEAGICWINSWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMGPFQSIF 8vqz C 2.05 BS01 C5P C 1 W152 G229 G230 E387 F389 W149 G226 G227 E384 F386 1.2.1.8 0000166,0008802,0016491,0016620,0019285,0046872 A0A0H3FPU4 501 MAEQQLYIHGKFVAATSGKTFETINPATGEVLATVQAAGREDVDRAVKSAQQGQKVWAAMSAMARSRILRKAVDILRERNDELARLETLDTGKPLSETAAVDIVTGADVLEYYAGLIPALEGSQIPLRDSSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYREAGLPDGVFNVLPGIGAETGQYLTEHPDIAKISFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIIAEDANLDLAADIAMMANFYSSGQVCTNGTRVFVPAKFKAEFEHKILERVGRIRAGDLFADDTNFGPLVSFPHRQNVLRYIESGKSEGARLLCGGDVLKGEGFDNGAWVAPTVFTDCTDDMTIVREEIFGPVMSILSYDDEAEVIRRANATEYGLAAGVVTPDLNRAHRIIHQLEAGICWINSWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMGPFQSIF 8vqz D 2.05 BS01 C5P D 1 W152 G229 G230 H333 N336 E387 F389 W149 G226 G227 H330 N333 E384 F386 1.2.1.8 0000166,0008802,0016491,0016620,0019285,0046872 A0A0H3FPU4 501 MAEQQLYIHGKFVAATSGKTFETINPATGEVLATVQAAGREDVDRAVKSAQQGQKVWAAMSAMARSRILRKAVDILRERNDELARLETLDTGKPLSETAAVDIVTGADVLEYYAGLIPALEGSQIPLRDSSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYREAGLPDGVFNVLPGIGAETGQYLTEHPDIAKISFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIIAEDANLDLAADIAMMANFYSSGQVCTNGTRVFVPAKFKAEFEHKILERVGRIRAGDLFADDTNFGPLVSFPHRQNVLRYIESGKSEGARLLCGGDVLKGEGFDNGAWVAPTVFTDCTDDMTIVREEIFGPVMSILSYDDEAEVIRRANATEYGLAAGVVTPDLNRAHRIIHQLEAGICWINSWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMGPFQSIF 8xkf B 2.5 BS02 C5P B 1 S346 P349 K350 I351 T352 A377 T378 T379 S302 P305 K306 I307 T308 A333 T334 T335 2.7.7.60,4.6.1.12 0003824,0008299,0008685,0016114,0016779,0016829,0019288,0046872,0050518,0070567 O25664 38537721 503 HHIKQTSVVLLAAGESRRFSQTIKKQWLRSNHTPLWLSVYESFKEALDFKEIILVVSELDYIYIKRHYPEIKLVKGGASRQESVRNALKIIDSAYTLTSDVARGLANIEALKNLFLTLQQTSHYCIAPYLPCYDTAIYYNEALDREAIKLIQTPQLSHTKALQSALNQGDFKDESSAILQAFPDRVSYIEGSFTLFFNPAKDTFIGMGFDTHAFIKDKPMVLGGVVLDCEFGLKAHSDGDALLHAVIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFEMGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVSMRYKQKL 8xkf C 2.5 BS01 C5P B 1 D302 G304 D273 G275 2.7.7.60,4.6.1.12 0003824,0008299,0008685,0016114,0016779,0016829,0019288,0046872,0050518,0070567 O25664 38537721 503 HHHIKQTSVVLLAAGESRRFSQTIKKQWLRSNHTPLWLSVYESFKEALDFKEIILVVSELDYIYIKRHYPEIKLVKGGASRQESVRNALKIIDSAYTLTSDVARGLANIEALKNLFLTLQQTSHYCIAPYLPCYDTAIYYNEALDREAIKLIQTPQLSHTKALQSALNQGDFKDESSAILQAFPDRVSYIEGSKDLHKLTTSGDLKHFTLFFNPAKDTFIGMGFDTHAFIKDKPMVLGGVVLDCEFGLKAHSDGDALLHAVIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFEMGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVSMRYKQKL 8xkf D 2.5 BS02 C5P D 1 S346 K350 I351 T352 A377 T378 T379 S316 K320 I321 T322 A347 T348 T349 2.7.7.60,4.6.1.12 0003824,0008299,0008685,0016114,0016779,0016829,0019288,0046872,0050518,0070567 O25664 38537721 503 HHIKQTSVVLLAAGESRRFSQTIKKQWLRSNHTPLWLSVYESFKEALDFKEIILVVSELDYIYIKRHYPEIKLVKGGASRQESVRNALKIIDSAYTLTSDVARGLANIEALKNLFLTLQQTSHYCIAPYLPCYDTAIYYNEALDREAIKLIQTPQLSHTKALQSALNQGDFKDESSAILQAFPDRVSYIEGSKDLHKLTTSGDLKHFTLFFNPAKDTFIGMGFDTHAFIKDKPMVLGGVVLDCEFGLKAHSDGDALLHAVIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFEMGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVSMRYKQK 8xkf E 2.5 BS03 C5P F 1 D302 G304 D273 G275 2.7.7.60,4.6.1.12 0003824,0008299,0008685,0016114,0016779,0016829,0019288,0046872,0050518,0070567 O25664 38537721 502 HHHIKQTSVVLLAAGESRRFSQTIKKQWLRSNHTPLWLSVYESFKEALDFKEIILVVSELDYIYIKRHYPEIKLVKGGASRQESVRNALKIIDSAYTLTSDVARGLANIEALKNLFLTLQQTSHYCIAPYLPCYDTAIYYNEALDREAIKLIQTPQLSHTKALQSALNQGDFKDESSAILQAFPDRVSYIEGSKDLHKLTTSGDLKHFTLFFNPAKDTFIGMGFDTHAFIKDKPMVLGGVVLDCEFGLKAHSDGDALLHAVIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFEMGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVSMRYKQKL 8xkf F 2.5 BS01 C5P D 1 D302 G304 D258 G260 2.7.7.60,4.6.1.12 0003824,0008299,0008685,0016114,0016779,0016829,0019288,0046872,0050518,0070567 O25664 38537721 503 HHHIKQTSVVLLAAGESRRFSQTIKKQWLRSNHTPLWLSVYESFKEALDFKEIILVVSELDYIYIKRHYPEIKLVKGGASRQESVRNALKIIDSAYTLTSDVARGLANIEALKNLFLTLQQTSHYCIAPYLPCYDTAIYYNEALDREAIKLIQTPQLSHTKALQSALNQGDFKDESSAILQAFPDRVSYIEGSKLFFNPAKDTFIGMGFDTHAFIKDKPMVLGGVVLDCEFGLKAHSDGDALLHAVIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFEMGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVSMRYKQK 8xkf F 2.5 BS03 C5P F 1 S346 K350 I351 T352 A377 T378 T379 E381 S302 K306 I307 T308 A333 T334 T335 E337 2.7.7.60,4.6.1.12 0003824,0008299,0008685,0016114,0016779,0016829,0019288,0046872,0050518,0070567 O25664 38537721 502 HHHIKQTSVVLLAAGESRRFSQTIKKQWLRSNHTPLWLSVYESFKEALDFKEIILVVSELDYIYIKRHYPEIKLVKGGASRQESVRNALKIIDSAYTLTSDVARGLANIEALKNLFLTLQQTSHYCIAPYLPCYDTAIYYNEALDREAIKLIQTPQLSHTKALQSALNQGDFKDESSAILQAFPDRVSYIEGSKLFFNPAKDTFIGMGFDTHAFIKDKPMVLGGVVLDCEFGLKAHSDGDALLHAVIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFEMGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVSMRYKQK