5o22 A 2.1 BS01 C3R A 1 Y50 K54 I232 P260 G261 G264 P265 Y44 K48 I226 P254 G255 G258 P259 1.5.1.5,3.5.4.9 0000105,0003824,0004477,0004488,0005829,0006164,0006730,0009086,0016491,0016787,0035999,0042803 Kd=10nM -logKd/Ki=8.00, Kd=10nM P24186 29142318 301 AAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQ 5o22 B 2.1 BS01 C3R B 1 Y50 K54 P260 G261 G264 P265 Y46 K50 P256 G257 G260 P261 1.5.1.5,3.5.4.9 0000105,0003824,0004477,0004488,0005829,0006164,0006730,0009086,0016491,0016787,0035999,0042803 Kd=10nM P24186 29142318 301 GAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHD 5o22 C 2.1 BS01 C3R C 1 Y50 K54 P260 G261 G264 P265 T267 Y49 K53 P259 G260 G263 P264 T266 1.5.1.5,3.5.4.9 0000105,0003824,0004477,0004488,0005829,0006164,0006730,0009086,0016491,0016787,0035999,0042803 Kd=10nM P24186 29142318 301 AAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDP 5o22 D 2.1 BS01 C3R D 1 Y50 K54 P260 G264 P265 V268 Y43 K47 P248 G252 P253 V256 1.5.1.5,3.5.4.9 0000105,0003824,0004477,0004488,0005829,0006164,0006730,0009086,0016491,0016787,0035999,0042803 Kd=10nM P24186 29142318 301 GAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDP