3hio A 2.0 BS01 C2X A 1 D75 N78 Y80 V81 D96 D100 G121 Y123 I172 R180 W211 G212 R213 R258 D71 N74 Y76 V77 D92 D96 G117 Y119 I168 R176 W207 G208 R209 R254 V81 E177 R180 V77 E173 R176 3.2.2.22 0017148,0030598 -logKd/Ki=6.52, Ki=300nM P02879 19920175 268 QYPIINFTTAGATVQSYTNFIRAVRGRLTTGADVRHEIPVLPNRVGLPINQRFILVELSNHAELSVTLALDVTNAYVVGYRAGNSAYFFHPDNQEDAEAITHLFTDVQNRYTFAFGGNYDRLEQLAGNLRENIELGNGPLEEAISALYYYSTGGTQLPTLARSFIICIQMISEAARFQYIEGEMRTRIRYNRRSAPDPSVITLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFSVYDVSILIPIIALMVYRCAPPP 3hiw A 1.8 BS01 C2X A 1 N71 Y73 V74 E121 S122 Y123 V169 E174 R177 E206 N207 G210 R214 Y233 L254 N71 Y73 V74 E121 S122 Y123 V169 E174 R177 E206 N207 G210 R214 Y233 L254 V74 E174 R177 V74 E174 R177 3.2.2.22 0006952,0016787,0017148,0030598,0035821,0090729 Ki=3.9nM -logKd/Ki=8.06, Ki=8.7nM Q2QEH4 19920175 260 VIIYELNLQGTTKAQYSTFLKQLRDDIKDPNLHYGGTNLPVIKRPVGPPKFLRVNLKASTGTVSLAVQRSNLYVAAYLAKNNNKQFRAYYFKGFQITTNQLNNLFPEATGVSNQQELGYGESYPQIQNAAGVTRQQAGLGIKKLAESMTKVNGVARVEKDEALFLLIVVQMVGEAARFKYIENLVLNNFDTAKEVEPVPDRVIILENNWGLLSRAAKTANNGVFQTPLVLTSYAVPGVEWRVTTVAEVEIGIFLNVD 3hiw B 1.8 BS01 C2X A 1 N207 Y233 N207 Y233 V74 E174 R177 V74 E174 R177 3.2.2.22 0006952,0016787,0017148,0030598,0035821,0090729 Ki=3.9nM Q2QEH4 19920175 260 VIIYELNLQGTTKAQYSTFLKQLRDDIKDPNLHYGGTNLPVIKRPVGPPKFLRVNLKASTGTVSLAVQRSNLYVAAYLAKNNNKQFRAYYFKGFQITTNQLNNLFPEATGVSNQQELGYGESYPQIQNAAGVTRQQAGLGIKKLAESMTKVNGVARVEKDEALFLLIVVQMVGEAARFKYIENLVLNNFDTAKEVEPVPDRVIILENNWGLLSRAAKTANNGVFQTPLVLTSYAVPGVEWRVTTVAEVEIGIFLNVD 3hiw B 1.8 BS02 C2X B 1 Y73 V74 E121 S122 Y123 P124 E174 R177 E206 N207 W209 G210 R214 Y233 L254 Y73 V74 E121 S122 Y123 P124 E174 R177 E206 N207 W209 G210 R214 Y233 L254 V74 E174 R177 V74 E174 R177 3.2.2.22 0006952,0016787,0017148,0030598,0035821,0090729 Ki=3.9nM Q2QEH4 19920175 260 VIIYELNLQGTTKAQYSTFLKQLRDDIKDPNLHYGGTNLPVIKRPVGPPKFLRVNLKASTGTVSLAVQRSNLYVAAYLAKNNNKQFRAYYFKGFQITTNQLNNLFPEATGVSNQQELGYGESYPQIQNAAGVTRQQAGLGIKKLAESMTKVNGVARVEKDEALFLLIVVQMVGEAARFKYIENLVLNNFDTAKEVEPVPDRVIILENNWGLLSRAAKTANNGVFQTPLVLTSYAVPGVEWRVTTVAEVEIGIFLNVD