1mqh A 1.8 BS01 BWD A 1 Y61 L90 T91 R96 G141 S142 T143 L192 E193 M196 Y59 L88 T89 R94 G139 S140 T141 L190 E191 M194 ? 0015276,0016020 ic50=0.3uM -logKd/Ki=6.52, IC50=0.30uM Ki=61nM P19491 12872125 301 NKTVVVTTILESPYVMMKKNHEALEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECG 1mxu A 1.8 BS02 BWD A 1 Y61 L90 T91 R96 L138 G141 S142 T143 L192 E193 M196 Y58 L87 T88 R93 L135 G138 S139 T140 L189 E190 M193 ? 0015276,0016020 ic50=4uM -logKd/Ki=5.40, IC50=4.0uM Ki=61nM P19491 12731861 300 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 1mxu B 1.8 BS03 BWD B 1 Y61 T91 R96 L138 G141 S142 T143 L192 E193 M196 Y59 T89 R94 L136 G139 S140 T141 L190 E191 M194 ? 0015276,0016020 ic50=4uM Ki=61nM P19491 12731861 301 NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 1mxu C 1.8 BS02 BWD C 1 Y61 L90 T91 R96 L138 G141 S142 T143 L192 E193 M196 Y58 L87 T88 R93 L135 G138 S139 T140 L189 E190 M193 ? 0015276,0016020 ic50=4uM Ki=61nM P19491 12731861 302 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 1my3 A 1.75 BS02 BWD A 1 Y61 T91 R96 L138 G141 S142 T143 L192 E193 M196 Y58 T88 R93 L135 G138 S139 T140 L189 E190 M193 ? 0015276,0016020 -logKd/Ki=5.40, IC50=4.0uM Ki=61nM P19491 12731861 800 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 1my3 B 1.75 BS03 BWD B 1 Y61 L90 T91 R96 L138 G141 S142 T143 L192 E193 M196 Y59 L88 T89 R94 L136 G139 S140 T141 L190 E191 M194 ? 0015276,0016020 Ki=61nM P19491 12731861 801 NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 1my3 C 1.75 BS01 BWD C 1 Y61 L90 T91 R96 L138 G141 S142 T143 L192 E193 M196 Y58 L87 T88 R93 L135 G138 S139 T140 L189 E190 M193 ? 0015276,0016020 Ki=61nM P19491 12731861 802 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC