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BioLiP
Download all results in tab-seperated text for 16 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1fm6:D (2.1) BS02 BRL ? GO:0003677 ... P37231 10882139 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    2 1fm6:X (2.1) BS02 BRL ? GO:0003677 ... P37231 10882139 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    3 1zgy:A (1.8) BS02 BRL ? GO:0003677 ... P37231 15976031 MOAD: ic50=0.5uM
    BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    4 2prg:A (2.3) BS01 BRL ? GO:0003677 ... P37231 9744270 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    5 2prg:B (2.3) BS01 BRL ? GO:0003677 ... P37231 9744270 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    6 3cs8:A (2.3) BS02 BRL ? GO:0003677 ... P37231 18469005 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    7 3dzy:D (3.1) BS04 BRL ? GO:0003677 ... P37231 19043829 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    8 4ema:A (2.545) BS01 BRL ? GO:0003677 ... P37231 22649490 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    9 4o8f:A (2.6) BS01 BRL ? GO:0003677 ... P37231 25004973 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    10 4o8f:B (2.6) BS01 BRL ? GO:0003677 ... P37231 25004973 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    11 4xld:A (2.45) BS01 BRL ? GO:0003677 ... P37231 26249358 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    12 5ji0:D (1.98) BS02 BRL ? GO:0003677 ... P37231 N/A BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    13 5ycp:A (2.0) BS02 BRL ? GO:0003677 ... P37231 29311579 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    14 6md4:A (2.24) BS01 BRL ? GO:0003677 ... P37231 30575522 PDBbind: -logKd/Ki=6.16, Kd=0.69uM
    BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    15 6onj:A (2.3) BS02 BRL ? GO:0003677 ... P37231 32075969 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    16 7awc:A (1.74) BS01 BRL ? GO:0003677 ... P37231 33989565 BindingDB: EC50=40nM, IC50=1.000000nM, Ki=8nM, Kd=0.145000nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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