4b5b A 2.055 BS01 BBE A 1 S41 L45 Y113 G115 V250 A251 E255 I256 S41 L45 Y113 G115 V250 A251 E255 I256 2.7.7.24 0000166,0008879,0009058,0009244,0016779,0019305,0045226,0046872 ic50=0.387uM -logKd/Ki=6.41, IC50=0.387uM IC50=387nM Q9HU22 23138692 400 MKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY 4b5b B 2.055 BS01 BBE B 1 S41 L45 Y113 G115 H119 V250 I256 S41 L45 Y113 G115 H119 V250 I256 2.7.7.24 0000166,0008879,0009058,0009244,0016779,0019305,0045226,0046872 ic50=0.387uM IC50=387nM Q9HU22 23138692 400 MKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY 4b5b C 2.055 BS01 BBE C 1 S41 L45 Y113 G115 H119 V250 E255 R259 S41 L45 Y113 G115 H119 V248 E253 R257 2.7.7.24 0000166,0008879,0009058,0009244,0016779,0019305,0045226,0046872 ic50=0.387uM -logKd/Ki=6.41, IC50=0.387uM IC50=387nM Q9HU22 23138692 400 MKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY 4b5b D 2.055 BS01 BBE D 1 S41 L45 Y113 Y114 G115 V250 A251 E255 I256 R259 S41 L45 Y113 Y114 G115 V250 A251 E255 I256 R259 2.7.7.24 0000166,0008879,0009058,0009244,0016779,0019305,0045226,0046872 ic50=0.387uM IC50=387nM Q9HU22 23138692 400 MKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY