3h2o A 2.7 BS01 B63 A 1 N120 I122 M145 D184 G188 G216 K220 S221 R254 N110 I112 M135 D174 G178 G206 K210 S211 R244 V28 D54 K220 R254 V27 D53 K210 R244 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 -logKd/Ki=4.59, IC50=25.9uM IC50=25900nM Q81VW8 19899766 501 KWDYDLRCGEYTLNLNEKTLIMGILNVTPDSFSDGGSYNEVDAAVRHAKEMRDEGAHIIDIGKVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAHIINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVRDENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEGTGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGK 3h2o B 2.7 BS01 B63 B 1 D101 N120 I122 M145 D184 G188 F189 G216 K220 S221 R254 D89 N108 I110 M133 D172 G176 F177 G204 K208 S209 R242 V28 D54 K220 R254 V28 D50 K208 R242 2.5.1.15 0004156,0005829,0009396,0016740,0042558,0044237,0046654,0046656,0046872 IC50=25900nM Q81VW8 19899766 502 MKWDYDLRCGEYTLNLNEKTLIMGILNVTPDGGSYNEVDAAVRHAKEMRDEGAHIIDIGGEVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAHIINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVRDENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEGTGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGK