1rej A 2.2 BS01 B1L A 1 G50 T51 G52 S53 F54 G55 R56 V57 A70 K72 L74 E121 Y122 E127 E170 L173 T183 D184 F327 G35 T36 G37 S38 F39 G40 R41 V42 A55 K57 L59 E106 Y107 E112 E155 L158 T168 D169 F312 D166 K168 E170 N171 D184 T201 D151 K153 E155 N156 D169 T186 2.7.11.11 0000122,0000287,0001669,0001707,0001843,0004672,0004674,0004679,0004691,0004712,0005515,0005524,0005634,0005654,0005737,0005739,0005813,0005829,0005886,0005930,0005952,0006397,0006468,0006611,0007189,0007193,0016310,0016607,0018105,0019901,0019904,0030145,0031410,0031514,0031594,0031625,0032024,0034237,0034605,0036126,0044853,0045542,0045667,0045722,0045879,0046827,0048240,0048471,0050804,0051726,0061136,0070417,0070613,0071333,0071374,0071377,0097546,0098794,0098978,0099170,0106310,0141156,1904262,1904539,1990044,2000810 Ki=5nM -logKd/Ki=8.30, Ki=5nM P05132 14705934 351 KEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF