1dio A 2.2 BS02 B12 B 1 T172 E205 Q267 M268 S301 M373 F374 T172 E205 Q267 M268 S301 M373 F374 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 10467140 601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 1dio B 2.2 BS01 B12 B 1 D112 K135 T137 L148 L153 P155 Q156 A157 S200 D67 K90 T92 L103 L108 P110 Q111 A112 S155 4.2.1.28 0016829,0050215 Q59471 10467140 601 GFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 1dio E 2.2 BS01 B12 E 1 D112 V113 K135 T137 L148 L153 P155 Q156 A157 S200 D67 V68 K90 T92 L103 L108 P110 Q111 A112 S155 4.2.1.28 0016829,0050215 Q59471 10467140 601 GFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 1dio L 2.2 BS02 B12 E 1 E205 Q267 M268 S301 M373 F374 E205 Q267 M268 S301 M373 F374 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 10467140 601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 1e1c A 2.62 BS01 B12 A 1 Y89 L119 H122 A139 V206 R207 E247 G333 W334 E370 A371 A373 L374 G609 H610 D611 R612 G613 I617 Y621 S655 L657 G685 G686 V687 Y705 T706 T709 S714 Y88 L118 H121 A138 V205 R206 E246 G332 W333 E369 A370 A372 L373 G608 H609 D610 R611 G612 I616 Y620 S654 L656 G684 G685 V686 Y704 T705 T708 S713 Y89 Y243 A244 K604 D608 H610 Y88 Y242 A243 K603 D607 H609 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 10924114 800 STLPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYAMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 1e1c C 2.62 BS01 B12 C 1 Y89 L119 A139 V206 R207 E247 G333 W334 E370 A371 A373 L374 G609 H610 D611 R612 G613 I617 S655 L657 G685 G686 V687 Y705 T706 T709 Y88 L118 A138 V205 R206 E246 G332 W333 E369 A370 A372 L373 G608 H609 D610 R611 G612 I616 S654 L656 G684 G685 V686 Y704 T705 T708 Y89 Y243 A244 K604 D608 H610 Y88 Y242 A243 K603 D607 H609 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 10924114 800 STLPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYAMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 1g64 A 2.1 BS02 B12 A 1 W93 Y131 R161 W66 Y104 R134 N37 K39 K41 T42 T43 R51 F91 W93 E128 N10 K12 K14 T15 T16 R24 F64 W66 E101 2.5.1.17 0005524,0005737,0006779,0008817,0009236,0016740 P31570 11148030 800 RGIIIVFTGNGKGKTTAAFGTAARAVGHGKNVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWETQNREADTAACMAVWQHGKRMLADPLLDMVVLDELTYMVAYDYLPLEEVISALNARPGHQTVIITGRGCHRDILDLADTVSELRPVKHAFDAGVKAQMGIDY 1i9c A 1.9 BS01 B12 A 1 S13 D14 C15 H16 A17 G19 L23 S61 L63 Y64 G65 G91 G92 N93 V95 V96 T121 S13 D14 C15 H16 A17 G19 L23 S61 L63 Y64 G65 G91 G92 N93 V95 V96 T121 V10 D14 H16 V10 D14 H16 5.4.99.1 0005515,0016853,0016866,0019553,0019670,0031419,0046872,0050097 P80078 11592143 800 MEKKTIVLGVIGSDCHAVGNKILDHAFTNAGFNVVNIGVLSPQENFIKAAIETKADAILVSSLYGQGEIDCKGLRQKCDEAGLEGILLYVGGNIVVGKQHWPDVEKRFKDMGYDRVYAPGTPPEVGIADLKKDLNIE 1i9c B 1.9 BS01 B12 A 1 A97 R100 N123 T220 M294 G295 G296 F297 E330 G333 I334 F471 A97 R100 N123 T220 M294 G295 G296 F297 E330 G333 I334 F471 R100 E171 R100 E171 5.4.99.1 0003824,0005515,0016853,0016866,0019553,0019670,0031419,0050097 P80077 11592143 800 MELKNKKWTDEEFHKQREEVLQQWPTGKEVDLQEAVDYLKKIPAEKNFAEKLVLAKKKGITMAQPRAGVALLDEHIELLRYLQDEGGADFLPSTIDAYTRQNRYDECENGIKESEKAGRSLLNGFPGVNFGVKGCRKVLEAVNLPLQARHGTPDSRLLAEIIHAGGWTSNEGGGISYNVPYAKNVTIEKSLLDWQYCDRLVGFYEEQGVHINREPFGPLTGTLVPPSMSNAVGITEALLAAEQGVKNITVGYGECGNMIQDIAALRCLEEQTNEYLKAYGYNDVFVTTVFHQWMGGFPQDESKAFGVIVTATTIAALAGATKVIVKTPHEAIGIPTKEANAAGIKATKMALNMLEGQRMPMSKELETEMAVIKAETKCILDKMFELGKGDLAIGTVKAFETGVMDIPFGPSKYNAGKMMPVRDNLGCVRYLEFGNVPFTEEIKNYNRERLQERAKFEGRDVSFQMVIDDIFAVGKGRLIGRPE 1i9c C 1.9 BS01 B12 C 1 S13 D14 C15 H16 A17 G19 L23 S61 L63 Y64 G65 G91 G92 N93 V95 V96 T121 P123 S13 D14 C15 H16 A17 G19 L23 S61 L63 Y64 G65 G91 G92 N93 V95 V96 T121 P123 V10 D14 H16 V10 D14 H16 5.4.99.1 0005515,0016853,0016866,0019553,0019670,0031419,0046872,0050097 P80078 11592143 800 MEKKTIVLGVIGSDCHAVGNKILDHAFTNAGFNVVNIGVLSPQENFIKAAIETKADAILVSSLYGQGEIDCKGLRQKCDEAGLEGILLYVGGNIVVGKQHWPDVEKRFKDMGYDRVYAPGTPPEVGIADLKKDLNIE 1i9c D 1.9 BS01 B12 C 1 A97 R100 N123 Y181 T220 M294 G295 G296 F297 E330 A331 G333 I334 F471 A97 R100 N123 Y181 T220 M294 G295 G296 F297 E330 A331 G333 I334 F471 R100 E171 R100 E171 5.4.99.1 0003824,0005515,0016853,0016866,0019553,0019670,0031419,0050097 P80077 11592143 800 MELKNKKWTDEEFHKQREEVLQQWPTGKEVDLQEAVDYLKKIPAEKNFAEKLVLAKKKGITMAQPRAGVALLDEHIELLRYLQDEGGADFLPSTIDAYTRQNRYDECENGIKESEKAGRSLLNGFPGVNFGVKGCRKVLEAVNLPLQARHGTPDSRLLAEIIHAGGWTSNEGGGISYNVPYAKNVTIEKSLLDWQYCDRLVGFYEEQGVHINREPFGPLTGTLVPPSMSNAVGITEALLAAEQGVKNITVGYGECGNMIQDIAALRCLEEQTNEYLKAYGYNDVFVTTVFHQWMGGFPQDESKAFGVIVTATTIAALAGATKVIVKTPHEAIGIPTKEANAAGIKATKMALNMLEGQRMPMSKELETEMAVIKAETKCILDKMFELGKGDLAIGTVKAFETGVMDIPFGPSKYNAGKMMPVRDNLGCVRYLEFGNVPFTEEIKNYNRERLQERAKFEGRDVSFQMVIDDIFAVGKGRLIGRPE 1iwb A 1.85 BS04 B12 B 1 T172 Q267 M268 S301 M373 F374 T172 Q267 M268 S301 M373 F374 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 12379103 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 1iwb B 1.85 BS01 B12 B 1 D112 K135 T137 L148 N150 L153 P155 Q156 A157 Y196 S200 D67 K90 T92 L103 N105 L108 P110 Q111 A112 Y151 S155 4.2.1.28 0016829,0050215 Q59471 12379103 1601 GFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVA 1iwb E 1.85 BS01 B12 E 1 D112 K135 T137 L148 L153 P155 Q156 A157 P158 Y196 S200 D67 K90 T92 L103 L108 P110 Q111 A112 P113 Y151 S155 4.2.1.28 0016829,0050215 Q59471 12379103 1602 GFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRV 1iwb L 1.85 BS04 B12 E 1 E205 Q267 M268 S301 F374 E205 Q267 M268 S301 F374 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 12379103 1602 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 1iwp A 2.1 BS01 B12 B 1 T173 V174 A177 S203 V204 E206 D235 L268 M269 S302 M374 F375 T173 V174 A177 S203 V204 E206 D235 L268 M269 S302 M374 F375 Q142 H144 E171 E222 Q297 D336 S363 Q142 H144 E171 E222 Q297 D336 S363 4.2.1.30 0003824,0016829,0016836,0031419,0046405 Q59476 12230560 1601 MKRSKRFAVLAQRPVNQDGLIGEWPEEGLIAMDSPFDPVSSVKVDNGLIVELDGKRRDQFDMIDRFIADYAINVERTEQAMRLEAVEIARMLVDIHVSREEIIAITTAITPAKAVEVMAQMNVVEMMMALQKMRARRTPSNQCHVTNLKDNPVQIAADAAEAGIRGFSEQETTVGIARYAPFNALALLVGSQCGRPGVLTQCSVEEATELELGMRGLTSYAETVSVYGTEAVFTDGDDTPWSKAFLASAYASRGLKMRYTSGTGSEALMGYSESKSMLYLESRCIFITKGAGVQGLQNGAVSCIGMTGAVPSGIRAVLAENLIASMLDLEVASANDQTFSHSDIRRTARTLMQMLPGTDFIFSGYSAVPNYDNMFAGSNFDAEDFDDYNILQRDLMVDGGLRPVTEAETIAIRQKAARAIQAVFRELGLPPIADEEVEAATYAHGSNEMPPRNVVEDLSAVEEMMKRNITGLDIVGALSRSGFEDIASNILNMLRQRVTGDYLQTSAILDRQFEVVSAVNDINDYQGPGTGYRISAERWAEIKNIPGVVQPDTIE 1iwp B 2.1 BS01 B12 B 1 D79 V80 S81 K102 T104 L115 N117 L120 S122 Q123 A124 M164 A167 D69 V70 S71 K92 T94 L105 N107 L110 S112 Q113 A114 M154 A157 4.2.1.28,4.2.1.30 0016829,0046405,0050215 O08505 12230560 1601 FTLKTREGGVASADERADEVVIGVGPAFDKHQHHTLIDMPHGAILKELIAGVEEEGLHARVVRILRTSDVSFMAWDAANLSGSGIGIGIQSKGTTVIHQRDLLPLSNLELFSQAPLLTLETYRQIGKNAARYARKESPSPVPVVNDQMVRPKFMAKAALFHIKETKHVVQDAEPVTLHIDLVRE 1iwp E 2.1 BS01 B12 E 1 D79 V80 K102 T104 L115 N117 L120 S122 Q123 A124 M164 A167 D69 V70 K92 T94 L105 N107 L110 S112 Q113 A114 M154 A157 4.2.1.28,4.2.1.30 0016829,0046405,0050215 O08505 12230560 2601 FTLKTREGGVASADERADEVVIGVGPAFDKHQHHTLIDMPHGAILKELIAGVEEEGLHARVVRILRTSDVSFMAWDAANLSGSGIGIGIQSKGTTVIHQRDLLPLSNLELFSQAPLLTLETYRQIGKNAARYARKESPSPVPVVNDQMVRPKFMAKAALFHIKETKHVVQDAEPVTLHIDLVRE 1iwp L 2.1 BS01 B12 E 1 T173 V174 S203 E206 D235 L268 M269 S302 M374 F375 A376 T173 V174 S203 E206 D235 L268 M269 S302 M374 F375 A376 4.2.1.30 0003824,0016829,0016836,0031419,0046405 Q59476 12230560 2601 MKRSKRFAVLAQRPVNQDGLIGEWPEEGLIAMDSPFDPVSSVKVDNGLIVELDGKRRDQFDMIDRFIADYAINVERTEQAMRLEAVEIARMLVDIHVSREEIIAITTAITPAKAVEVMAQMNVVEMMMALQKMRARRTPSNQCHVTNLKDNPVQIAADAAEAGIRGFSEQETTVGIARYAPFNALALLVGSQCGRPGVLTQCSVEEATELELGMRGLTSYAETVSVYGTEAVFTDGDDTPWSKAFLASAYASRGLKMRYTSGTGSEALMGYSESKSMLYLESRCIFITKGAGVQGLQNGAVSCIGMTGAVPSGIRAVLAENLIASMLDLEVASANDQTFSHSDIRRTARTLMQMLPGTDFIFSGYSAVPNYDNMFAGSNFDAEDFDDYNILQRDLMVDGGLRPVTEAETIAIRQKAARAIQAVFRELGLPPIADEEVEAATYAHGSNEMPPRNVVEDLSAVEEMMKRNITGLDIVGALSRSGFEDIASNILNMLRQRVTGDYLQTSAILDRQFEVVSAVNDINDYQGPGTGYRISAERWAEIKNIPGVVQPDTIE 1k7y A 3.0 BS01 B12 A 1 I751 G762 V766 G802 L803 S804 L806 T808 L831 G833 G834 A835 N859 A860 D1093 A1136 P1137 G1138 Y1139 H1145 A1170 M1171 G1174 S1176 V1177 S1178 I101 G112 V116 G152 L153 S154 L156 T158 L181 G183 G184 A185 N209 A210 D443 A486 P487 G488 Y489 H495 A520 M521 G524 S526 V527 S528 D757 G759 S810 D107 G109 S160 2.1.1.13 0008705,0009086,0031419,0046872 P13009 11731805 1248 QAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEQGKTNGKMVIATVKGDVGDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYARRKGMSVTEVERWLAPNLGYDAD 1k98 A 3.75 BS01 B12 A 1 G759 G762 V766 G802 L803 L806 I807 T808 G833 G834 A835 V857 N859 A860 D1093 P1137 G1138 Y1139 H1145 A1170 M1171 G1174 S1176 V1177 S1178 G109 G112 V116 G152 L153 L156 I157 T158 G183 G184 A185 V207 N209 A210 D443 P487 G488 Y489 H495 A520 M521 G524 S526 V527 S528 D757 G759 S810 D107 G109 S160 2.1.1.13 0008705,0009086,0031419,0046872 P13009 11731805 1248 QAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEQGKTNGKMVIATVKGDVGDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYARRKGMSVTEVERWLAPNLGYDAD 1mmf A 2.5 BS01 B12 B 1 T173 E206 M269 M374 F375 T173 E206 M269 M374 F375 Q142 H144 E171 E222 Q297 D336 S363 Q142 H144 E171 E222 Q297 D336 S363 4.2.1.30 0003824,0016829,0016836,0031419,0046405 Q59476 12538056 601 MKRSKRFAVLAQRPVNQDGLIGEWPEEGLIAMDSPFDPVSSVKVDNGLIVELDGKRRDQFDMIDRFIADYAINVERTEQAMRLEAVEIARMLVDIHVSREEIIAITTAITPAKAVEVMAQMNVVEMMMALQKMRARRTPSNQCHVTNLKDNPVQIAADAAEAGIRGFSEQETTVGIARYAPFNALALLVGSQCGRPGVLTQCSVEEATELELGMRGLTSYAETVSVYGTEAVFTDGDDTPWSKAFLASAYASRGLKMRYTSGTGSEALMGYSESKSMLYLESRCIFITKGAGVQGLQNGAVSCIGMTGAVPSGIRAVLAENLIASMLDLEVASANDQTFSHSDIRRTARTLMQMLPGTDFIFSGYSAVPNYDNMFAGSNFDAEDFDDYNILQRDLMVDGGLRPVTEAETIAIRQKAARAIQAVFRELGLPPIADEEVEAATYAHGSNEMPPRNVVEDLSAVEEMMKRNITGLDIVGALSRSGFEDIASNILNMLRQRVTGDYLQTSAILDRQFEVVSAVNDINDYQGPGTGYRISAERWAEIKNIPGVVQPD 1mmf B 2.5 BS01 B12 B 1 D79 K102 T104 L115 N117 L120 S122 Q123 A124 M164 D69 K92 T94 L105 N107 L110 S112 Q113 A114 M154 4.2.1.28,4.2.1.30 0016829,0046405,0050215 O08505 12538056 601 FTLKTREGGVASADERADEVVIGVGPAFDKHQHHTLIDMPHGAILKELIAGVEEEGLHARVVRILRTSDVSFMAWDAANLSGSGIGIGIQSKGTTVIHQRDLLPLSNLELFSQAPLLTLETYRQIGKNAARYARKESPSPVPVVNDQMVRPKFMAKAALFHIKETKHVVQDAEPVTLHIDL 1mmf E 2.5 BS01 B12 E 1 S81 K102 T104 L115 N117 L120 S122 Q123 A124 P125 S72 K93 T95 L106 N108 L111 S113 Q114 A115 P116 4.2.1.28,4.2.1.30 0016829,0046405,0050215 O08505 12538056 602 SFTLKTREGGVASADERADEVVIGVGPAFDKHQHHTLIDMPHGAILKELIAGVEEEGLHARVVRILRTSDVSFMAWDAANLSGSGIGIGIQSKGTTVIHQRDLLPLSNLELFSQAPLLTLETYRQIGKNAARYARKESPSPVPVVNDQMVRPKFMAKAALFHIKETKHVVQDAEPVTLHIDLVR 1mmf L 2.5 BS01 B12 E 1 T173 E206 L268 M269 M374 F375 T173 E206 L268 M269 M374 F375 4.2.1.30 0003824,0016829,0016836,0031419,0046405 Q59476 12538056 602 MKRSKRFAVLAQRPVNQDGLIGEWPEEGLIAMDSPFDPVSSVKVDNGLIVELDGKRRDQFDMIDRFIADYAINVERTEQAMRLEAVEIARMLVDIHVSREEIIAITTAITPAKAVEVMAQMNVVEMMMALQKMRARRTPSNQCHVTNLKDNPVQIAADAAEAGIRGFSEQETTVGIARYAPFNALALLVGSQCGRPGVLTQCSVEEATELELGMRGLTSYAETVSVYGTEAVFTDGDDTPWSKAFLASAYASRGLKMRYTSGTGSEALMGYSESKSMLYLESRCIFITKGAGVQGLQNGAVSCIGMTGAVPSGIRAVLAENLIASMLDLEVASANDQTFSHSDIRRTARTLMQMLPGTDFIFSGYSAVPNYDNMFAGSNFDAEDFDDYNILQRDLMVDGGLRPVTEAETIAIRQKAARAIQAVFRELGLPPIADEEVEAATYAHGSNEMPPRNVVEDLSAVEEMMKRNITGLDIVGALSRSGFEDIASNILNMLRQRVTGDYLQTSAILDRQFEVVSAVNDINDYQGPGTGYRISAERWAEIKNIPGVVQPDTIE 1req A 2.0 BS01 B12 A 1 Y89 L119 A139 V206 R207 E247 G333 W334 E370 A371 A373 G609 H610 D611 R612 G613 I617 Y621 S655 L657 G685 G686 Y705 T706 T709 Y88 L118 A138 V205 R206 E246 G332 W333 E369 A370 A372 G608 H609 D610 R611 G612 I616 Y620 S654 L656 G684 G685 Y704 T705 T708 Y89 Y243 H244 K604 D608 H610 Y88 Y242 H243 K603 D607 H609 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 8805541 800 STLPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 1req C 2.0 BS01 B12 C 1 Y89 L119 A139 V206 R207 E247 G333 W334 E370 A371 A373 G609 H610 D611 R612 G613 I617 Y621 S655 L657 G659 G685 G686 Y705 T706 T709 Y88 L118 A138 V205 R206 E246 G332 W333 E369 A370 A372 G608 H609 D610 R611 G612 I616 Y620 S654 L656 G658 G684 G685 Y704 T705 T708 Y89 Y243 H244 K604 D608 H610 Y88 Y242 H243 K603 D607 H609 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 8805541 800 STLPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 1xrs B 2.8 BS01 B12 B 1 D131 A132 H133 T134 V135 I140 Y146 L185 V186 S187 T191 L219 C220 G221 G222 P223 F239 G240 P241 R243 D82 A83 H84 T85 V86 I91 Y97 L136 V137 S138 T142 L170 C171 G172 G173 P174 F190 G191 P192 R194 K144 K95 5.4.3.3 0016853,0031419,0046872,0046983,0047826 E3PRJ4 15514022 800 KVQLSFTLPLKNNERSAEAAKQIALKMGLEEPSVVMQQSLDEEFTFFVVYGNEILSMEETDEYIKENIGRKIVVVGASTGTDAHTVGIDAIMNMKGYAGHYGLERYEMIDAYNLGSQVANEDFIKKAVELEADVLLVSQTVTQKNVHIQNMTHLIELLEAEGLRDRFVLLCGGPRINNEIAKELGYDAGFGPGRFADDVATFAVKTLNDRMN 2bb5 A 3.2 BS01 B12 A 1 G85 Q86 T134 Y137 Q138 H172 H173 D176 N224 Y226 S227 M270 S357 L358 S359 G360 Y362 L363 F376 W377 Q378 L379 L387 L388 G390 W409 G85 Q86 T134 Y137 Q138 H172 H173 D176 N224 Y226 S227 M270 S357 L358 S359 G360 Y362 L363 F376 W377 Q378 L379 L387 L388 G390 W409 ? 0005515,0005576,0005615,0005886,0006824,0009897,0015889,0031419,0043202,0046872,0140355 P20062 16537422 0 EMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRLSSLQAGTKEDLYLHSLKLGYQQCLLGSAFSEDDGDCQGKPSMGQLALYLLALRANCEFVRGHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVREEILKAQTPEGHFGNVYSTPLALQFLMTSPMPGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW 2bb5 B 3.2 BS01 B12 B 1 G85 Q86 T134 Y137 Q138 H172 H173 D176 N224 Y226 S227 M270 S357 L358 S359 G360 Y362 L363 F376 W377 L379 L387 L388 G390 W409 G85 Q86 T134 Y137 Q138 H172 H173 D176 N224 Y226 S227 M270 S357 L358 S359 G360 Y362 L363 F376 W377 L379 L387 L388 G390 W409 ? 0005515,0005576,0005615,0005886,0006824,0009897,0015889,0031419,0043202,0046872,0140355 P20062 16537422 410 EMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRLSSLQAGTKEDLYLHSLKLGYQQCLLGSAFSEDDGDCQGKPSMGQLALYLLALRANCEFVRGHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVREEILKAQTPEGHFGNVYSTPLALQFLMTSPMPGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW 2bb6 A 2.0 BS01 B12 A 1 G85 Q86 Y137 Q138 H175 V176 D179 N227 Y229 S230 M273 S362 L363 S364 G365 P366 F367 L368 F381 W382 Q383 V384 L392 Q393 G395 W414 G85 Q86 Y137 Q138 H175 V176 D179 N227 Y229 S230 M273 S362 L363 S364 G365 P366 F367 L368 F381 W382 Q383 V384 L392 Q393 G395 W414 ? 0005576,0005615,0006824,0015889,0031419,0046872 Q9XSC9 16537422 0 NICEITEVDSTLVERLGQRLLPWMDRLSQEQLNPSIYVGLRLSSLQAGAKEAHYLHSLKLSYQQSLLRPASNKDDNDSEAKPSMGQLALYLLALRANCEFIGGRKGDRLVSQLKRFLEDEKRAIGHNHQGHPRTSYYQYSLGILALCVHQKRVHDSVVGKLLYAVEHKPHLLQDHVSVDTMAMAGMAFSCLELSNLNPKQRNRINLALKRVQEKILKAQTPEGYFGNVYSTPLALQLLMGSLRPSVELGTACLKAKAALQASLQHKTFQNPLMISQLLPVLNQKSYVDLISPDCQAPRALLEPALETPPQAKVPKFIDVLLKVSGISPSYRHSVSVPAGSSLEDILKNAQEHGRFRFRTQASLSGPFLTSVLGRKAGEREFWQVLRDPDTPLQQGIADYRPKDGETIELRLVGW 2bb6 B 2.0 BS01 B12 B 1 G85 Q86 Y137 Q138 H175 V176 D179 N227 Y229 S230 M273 S362 L363 S364 G365 P366 F367 L368 F381 W382 Q383 V384 L392 Q393 G395 W414 G85 Q86 Y137 Q138 H175 V176 D179 N227 Y229 S230 M273 S362 L363 S364 G365 P366 F367 L368 F381 W382 Q383 V384 L392 Q393 G395 W414 ? 0005576,0005615,0006824,0015889,0031419,0046872 Q9XSC9 16537422 0 NICEITEVDSTLVERLGQRLLPWMDRLSQEQLNPSIYVGLRLSSLQAGAKEAHYLHSLKLSYQQSLLRPASNKDDNDSEAKPSMGQLALYLLALRANCEFIGGRKGDRLVSQLKRFLEDEKRAIGHNHQGHPRTSYYQYSLGILALCVHQKRVHDSVVGKLLYAVEHKPHLLQDHVSVDTMAMAGMAFSCLELSNLNPKQRNRINLALKRVQEKILKAQTPEGYFGNVYSTPLALQLLMGSLRPSVELGTACLKAKAALQASLQHKTFQNPLMISQLLPVLNQKSYVDLISPDCQAPRALLEPALETPPQAKVPKFIDVLLKVSGISPSYRHSVSVPAGSSLEDILKNAQEHGRFRFRTQASLSGPFLTSVLGRKAGEREFWQVLRDPDTPLQQGIADYRPKDGETIELRLVGW 2bb6 C 2.0 BS01 B12 C 1 G85 Q86 Y137 Q138 H175 V176 D179 N227 Y229 S230 M273 S362 L363 S364 G365 P366 F367 L368 F381 W382 Q383 V384 L392 Q393 G395 W414 G85 Q86 Y137 Q138 H175 V176 D179 N227 Y229 S230 M273 S362 L363 S364 G365 P366 F367 L368 F381 W382 Q383 V384 L392 Q393 G395 W414 ? 0005576,0005615,0006824,0015889,0031419,0046872 Q9XSC9 16537422 0 NICEITEVDSTLVERLGQRLLPWMDRLSQEQLNPSIYVGLRLSSLQAGAKEAHYLHSLKLSYQQSLLRPASNKDDNDSEAKPSMGQLALYLLALRANCEFIGGRKGDRLVSQLKRFLEDEKRAIGHNHQGHPRTSYYQYSLGILALCVHQKRVHDSVVGKLLYAVEHKPHLLQDHVSVDTMAMAGMAFSCLELSNLNPKQRNRINLALKRVQEKILKAQTPEGYFGNVYSTPLALQLLMGSLRPSVELGTACLKAKAALQASLQHKTFQNPLMISQLLPVLNQKSYVDLISPDCQAPRALLEPALETPPQAKVPKFIDVLLKVSGISPSYRHSVSVPAGSSLEDILKNAQEHGRFRFRTQASLSGPFLTSVLGRKAGEREFWQVLRDPDTPLQQGIADYRPKDGETIELRLVGW 2bb6 D 2.0 BS01 B12 D 1 G85 Q86 Y137 Q138 H175 D179 N227 Y229 S230 M273 Q276 S362 L363 S364 G365 P366 F367 L368 F381 W382 Q383 V384 L392 Q393 G395 W414 G85 Q86 Y137 Q138 H175 D179 N227 Y229 S230 M273 Q276 S362 L363 S364 G365 P366 F367 L368 F381 W382 Q383 V384 L392 Q393 G395 W414 ? 0005576,0005615,0006824,0015889,0031419,0046872 Q9XSC9 16537422 0 NICEITEVDSTLVERLGQRLLPWMDRLSQEQLNPSIYVGLRLSSLQAGAKEAHYLHSLKLSYQQSLLRPASNKDDNDSEAKPSMGQLALYLLALRANCEFIGGRKGDRLVSQLKRFLEDEKRAIGHNHQGHPRTSYYQYSLGILALCVHQKRVHDSVVGKLLYAVEHKPHLLQDHVSVDTMAMAGMAFSCLELSNLNPKQRNRINLALKRVQEKILKAQTPEGYFGNVYSTPLALQLLMGSLRPSVELGTACLKAKAALQASLQHKTFQNPLMISQLLPVLNQKSYVDLISPDCQAPRALLEPALETPPQAKVPKFIDVLLKVSGISPSYRHSVSVPAGSSLEDILKNAQEHGRFRFRTQASLSGPFLTSVLGRKAGEREFWQVLRDPDTPLQQGIADYRPKDGETIELRLVGW 2bbc A 2.4 BS01 B12 A 1 G85 Q86 Y137 Q138 H175 D179 N227 Y229 S230 N270 M273 S362 L363 S364 G365 P366 F367 L368 F381 W382 Q383 V384 L392 Q393 G395 W414 G85 Q86 Y137 Q138 H175 D179 N227 Y229 S230 N270 M273 S362 L363 S364 G365 P366 F367 L368 F381 W382 Q383 V384 L392 Q393 G395 W414 ? 0005576,0005615,0006824,0015889,0031419,0046872 Q9XSC9 16537422 0 NICEITEVDSTLVERLGQRLLPWMDRLSQEQLNPSIYVGLRLSSLQAGAKEAHYLHSLKLSYQQSLLRPASNKDDNDSEAKPSMGQLALYLLALRANCEFIGGRKGDRLVSQLKRFLEDEKRAIGHNHQGHPRTSYYQYSLGILALCVHQKRVHDSVVGKLLYAVEHKPHLLQDHVSVDTMAMAGMAFSCLELSNLNPKQRNRINLALKRVQEKILKAQTPEGYFGNVYSTPLALQLLMGSLRPSVELGTACLKAKAALQASLQHKTFQNPLMISQLLPVLNQKSYVDLISPDCQAPRALLEPALETPPQAKVPKFIDVLLKVSGISPSYRHSVSVPAGSSLEDILKNAQEHGRFRFRTQASLSGPFLTSVLGRKAGEREFWQVLRDPDTPLQQGIADYRPKDGETIELRLVGW 2h9a A 1.9 BS01 B12 A 1 T339 F342 T345 V349 T370 S371 V372 T374 A377 I405 P407 G428 P429 R430 E431 S432 T281 F284 T287 V291 T312 S313 V314 T316 A319 I347 P349 G370 P371 R372 E373 S374 ? 0005506,0008168,0044237,0046356,0046872,0051536,0051539 Q3ACS3 16983091 1442 PPVALIKVGKGEKVLEIGHETVLFRHDKRFEHPCGLAILVEDTLSEGEIKERVEKINKLVFDRVGQMHSVNLVALKGSSQDAATFAKAVATAREVTDLPFILIGTPEQLAAALETEGANNPLLYAATADNYEQMVELAKKYNVPLTVSAKGLDALAELVQKITALGYKNLILDPQPENISEGLFYQTQIRRLAIKKLFRPFGYPTIAFALDENPYQAVMEASVYIAKYAGIIVLNTVEPADILPLITLRLNIYTDPQKPIAVEPKVYEILNPGPDAPVFITTNFSLTYFCVAGDVEGARIPAYILPVDTDGTSVLTAWAAGKFTPEKIAQFLKESGIAEKVNHRKAILPGGVAVLSGKLQELSGWEILVGPRESSGINSFIKQ 2h9a B 1.9 BS01 B12 A 1 P181 L182 L186 L209 I210 G211 Y219 E249 P179 L180 L184 L207 I208 G209 Y217 E247 ? 0044237 Q3ACS0 16983091 1442 VEVLKEKWNSKVVEVTLGTGDKTVTLGGDSTLPFLTFEGEMPNPPRFALEVFDTPPTDWPDILVEPFKDVINDPVAWAKKCVEYGADIVALRLVSAHPDGQNRSGAELAEVCKAVADAIDVPLMIIGCGVEEKDAEIFPVIGEALSGRNCLLSSATKDNYKPIVATCMVHGHSVVASAPLDINLSKQLNIMIMEMNLAPNRIIMDPLIGALGYGIEYSYSIIERMRLGALTGDKILAMPVVCFIGQEAWKAKEAKDPEVAEWGDYALRAIHWETVTTVALIQAGGHLFVMRHPKSLAEVKEHLKRIL 2pmv A 2.6 BS01 B12 A 1 G72 H73 Y115 D153 D204 Y206 S207 Q252 S347 W348 G349 L350 V351 V352 Y367 W368 Q369 F370 L377 N378 E379 G380 Y399 G66 H67 Y109 D147 D198 Y200 S201 Q246 S326 W327 G328 L329 V330 V331 Y346 W347 Q348 F349 L356 N357 E358 G359 Y378 ? 0005515,0005576,0005615,0005768,0005902,0006824,0015889,0016324,0031419,0043202,0140355 P27352 17954916 1001 SCSVPSAQEPLVNGIQVLMENSVTSSAYPNPSILIAMNLAGAYNLKAQKLLTYQLMSSDNNDLTIGHLGLTIMALTSSCRDPGDKVSILQRQMENWAPSSPNAEASAFYGPSLAILALCQKNSEATLPIAVRFAKTLLANSSPFNVDTGAMATLALTCMYNKIPVGSEEGYRSLFGQVLKDIVEKISMKIKDNGIIGDIYSTGLAMQALSVTPEPSKKEWNCKKTTDMILNEIKQGKFHNPMSIAQILPSLKGKTYLDVPQVTCSPDTSASNITVIYTINNQLRGVELLFNETINVSVKSGSVLLVVLEEAQRKNPMFKFETTMTSWGLVVSSINNIAENVNHKTYWQFLSGVTPLNEGVADYIPFNHEHITANFTQY 2pmv C 2.6 BS01 B12 C 1 G72 H73 Y115 D153 D204 Y206 S207 Q252 S347 W348 G349 L350 V351 V352 Y367 W368 Q369 F370 P376 L377 N378 E379 G380 Y399 G66 H67 Y109 D147 D198 Y200 S201 Q246 S326 W327 G328 L329 V330 V331 Y346 W347 Q348 F349 P355 L356 N357 E358 G359 Y378 ? 0005515,0005576,0005615,0005768,0005902,0006824,0015889,0016324,0031419,0043202,0140355 P27352 17954916 1002 SCSVPSAQEPLVNGIQVLMENSVTSSAYPNPSILIAMNLAGAYNLKAQKLLTYQLMSSDNNDLTIGHLGLTIMALTSSCRDPGDKVSILQRQMENWAPSSPNAEASAFYGPSLAILALCQKNSEATLPIAVRFAKTLLANSSPFNVDTGAMATLALTCMYNKIPVGSEEGYRSLFGQVLKDIVEKISMKIKDNGIIGDIYSTGLAMQALSVTPEPSKKEWNCKKTTDMILNEIKQGKFHNPMSIAQILPSLKGKTYLDVPQVTCSPDTSASNITVIYTINNQLRGVELLFNETINVSVKSGSVLLVVLEEAQRKNPMFKFETTMTSWGLVVSSINNIAENVNHKTYWQFLSGVTPLNEGVADYIPFNHEHITANFTQY 2req A 2.5 BS02 B12 A 1 V206 R207 E247 A248 W334 A371 G609 H610 D611 R612 G613 I617 G653 S655 L657 A658 G685 G686 Y705 T706 T709 V203 R204 E244 A245 W331 A368 G606 H607 D608 R609 G610 I614 G650 S652 L654 A655 G682 G683 Y702 T703 T706 Y89 Y243 H244 K604 D608 H610 Y86 Y240 H241 K601 D605 H607 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 9655823 800 LPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 2req C 2.5 BS02 B12 C 1 L119 V206 R207 E247 W334 E370 A371 Q454 G609 H610 D611 R612 G613 I617 Y621 L657 A658 G685 G686 Y705 T706 T709 L116 V203 R204 E244 W331 E367 A368 Q451 G606 H607 D608 R609 G610 I614 Y618 L654 A655 G682 G683 Y702 T703 T706 Y89 Y243 H244 K604 D608 H610 Y86 Y240 H241 K601 D605 H607 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 9655823 800 LPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 2v3n A 2.73 BS01 B12 A 1 G85 Q86 Y137 Q138 D179 N227 Y229 M273 Q276 S362 L363 S364 G365 F367 L368 F381 W382 Q383 V384 L392 Q393 G395 W414 G85 Q86 Y137 Q138 D170 N218 Y220 M264 Q267 S353 L354 S355 G356 F358 L359 F372 W373 Q374 V375 L383 Q384 G386 W405 ? 0005576,0005615,0006824,0015889,0031419,0046872 Q9XSC9 17943552 1001 NICEITEVDSTLVERLGQRLLPWMDRLSQEQLNPSIYVGLRLSSLQAGAKEAHYLHSLKLSYQQSLLRPASNKDDNDSEAKPSMGQLALYLLALRANCEFIGGRKGDRLVSQLKRFLEDEKRAIGHNHQGHPRTSYYQYSLGILALCVHQKRVHDSVVGKLLYAVEHSVDTMAMAGMAFSCLELSNLNPKQRNRINLALKRVQEKILKAQTPEGYFGNVYSTPLALQLLMGSLRPSVELGTACLKAKAALQASLQHKTFQNPLMISQLLPVLNQKSYVDLISPDCQAPRALLEPALETPPQAKVPKFIDVLLKVSGISPSYRHSVSVPAGSSLEDILKNAQEHGRFRFRTQASLSGPFLTSVLGRKAGEREFWQVLRDPDTPLQQGIADYRPKDGETIELRLVGW 2v3p A 2.9 BS01 B12 A 1 G85 Q86 Y137 D179 N227 Y229 S230 M273 Q276 S362 L363 S364 G365 F367 L368 F381 W382 Q383 V384 L392 Q393 G395 W414 G85 Q86 Y137 D170 N218 Y220 S221 M264 Q267 S353 L354 S355 G356 F358 L359 F372 W373 Q374 V375 L383 Q384 G386 W405 ? 0005576,0005615,0006824,0015889,0031419,0046872 Q9XSC9 17943552 1415 NICEITEVDSTLVERLGQRLLPWMDRLSQEQLNPSIYVGLRLSSLQAGAKEAHYLHSLKLSYQQSLLRPASNKDDNDSEAKPSMGQLALYLLALRANCEFIGGRKGDRLVSQLKRFLEDEKRAIGHNHQGHPRTSYYQYSLGILALCVHQKRVHDSVVGKLLYAVEHSVDTMAMAGMAFSCLELSNLNPKQRNRINLALKRVQEKILKAQTPEGYFGNVYSTPLALQLLMGSLRPSVELGTACLKAKAALQASLQHKTFQNPLMISQLLPVLNQKSYVDLISPDCQAPRALLEPALETPPQAKVPKFIDVLLKVSGISPSYRHSVSVPAGSSLEDILKNAQEHGRFRFRTQASLSGPFLTSVLGRKAGEREFWQVLRDPDTPLQQGIADYRPKDGETIELRLVGW 2xij A 1.95 BS01 B12 A 1 L140 A160 V227 R228 E268 W356 A393 L394 G395 G626 H627 D628 R629 G630 I634 S672 L674 A675 G702 G703 F722 G723 T726 L105 A125 V192 R193 E233 W321 A358 L359 G360 G591 H592 D593 R594 G595 I599 S637 L639 A640 G667 G668 F687 G688 T691 Y110 Y264 H265 K621 D625 H627 Y75 Y229 H230 K586 D590 H592 5.4.99.2 0003824,0003924,0004494,0005515,0005737,0005739,0005759,0006790,0009791,0016853,0016866,0019678,0031419,0042802,0042803,0043547,0046872,0050667,0072341,1901290 P22033 20876572 800 QQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDTVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEK 2xiq A 1.95 BS01 B12 A 1 Y110 L140 H143 A160 R228 E268 G355 W356 E392 G395 L396 G626 H627 D628 R629 G630 I634 G670 S672 L674 A676 G702 G703 F722 G723 T726 Y75 L105 H108 A125 R193 E233 G320 W321 E357 G360 L361 G591 H592 D593 R594 G595 I599 G635 S637 L639 A641 G667 G668 F687 G688 T691 Y110 Y264 H265 K621 D625 H627 Y75 Y229 H230 K586 D590 H592 5.4.99.2 0003824,0003924,0004494,0005515,0005737,0005739,0005759,0006790,0009791,0016853,0016866,0019678,0031419,0042802,0042803,0043547,0046872,0050667,0072341,1901290 P22033 20876572 3001 QQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDTVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQQS 2xiq B 1.95 BS01 B12 B 1 Y110 L140 H143 A160 R228 E268 G355 W356 E392 G395 L396 G626 H627 D628 R629 G630 I634 S672 L674 G702 G703 V704 F722 G723 T726 Y75 L105 H108 A125 R193 E233 G320 W321 E357 G360 L361 G591 H592 D593 R594 G595 I599 S637 L639 G667 G668 V669 F687 G688 T691 Y110 Y264 H265 K621 D625 H627 Y75 Y229 H230 K586 D590 H592 5.4.99.2 0003824,0003924,0004494,0005515,0005737,0005739,0005759,0006790,0009791,0016853,0016866,0019678,0031419,0042802,0042803,0043547,0046872,0050667,0072341,1901290 P22033 20876572 3001 QQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDTVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQQ 2ycl A 1.95 BS01 B12 A 1 F337 T339 F342 T345 C348 V349 T370 S371 V372 L373 T374 I405 P407 P429 R430 S432 F336 T338 F341 T344 C347 V348 T369 S370 V371 L372 T373 I404 P406 P428 R429 S431 ? 0005506,0008168,0044237,0046356,0046872,0051536,0051539 Q3ACS3 21640123 1442 GLTGLEIYKHLPKKNCKECGQPTCLAFAMQIAAGKAGLDACPYVSDEAKELLESASAPPVALIKVGKGEKVLEIGHETVLFRHDKRFEHPCGLAILVEDTLSEGEIKERVEKINKLVFDRVGQMHSVNLVALKGSSQDAATFAKAVATAREVTDLPFILIGTPEQLAAALETEGANNPLLYAATADNYEQMVELAKKYNVPLTVSAKGLDALAELVQKITALGYKNLILDPQPENISEGLFYQTQIRRLAIKKLFRPFGYPTIAFALDENPYQAVMEASVYIAKYAGIIVLNTVEPADILPLITLRLNIYTDPQKPIAVEPKVYEILNPGPDAPVFITTNFSLTYFCVAGDVEGARIPAYILPVDTDGTSVLTAWAAGKFTPEKIAQFLKESGIAEKVNHRKAILPGGVAVLSGKLQELSGWEILVGPRESSGINSFIKQRW 2ycl B 1.95 BS01 B12 A 1 P181 L209 Y219 E249 P180 L208 Y218 E248 ? 0044237 Q3ACS0 21640123 1442 AVEVLKEKWNSKVVEVTLGTGDKTVTLGGDSTLPFLTFEGEMPNPPRFALEVFDTPPTDWPDILVEPFKDVINDPVAWAKKCVEYGADIVALRLVSAHPDGQNRSGAELAEVCKAVADAIDVPLMIIGCGVEEKDAEIFPVIGEALSGRNCLLSSATKDNYKPIVATCMVHGHSVVASAPLDINLSKQLNIMIMEMNLAPNRIIMDPLIGALGYGIEYSYSIIERMRLGALTGDKILAMPVVCFIGQEAWKAKEAKDPEVAEWGDYALRAIHWETVTTVALIQAGGHLFVMRHPKSLAEVKEHLKRILK 3abo A 2.1 BS02 B12 B 1 P194 A226 H227 Q246 S247 F258 F329 I330 M401 L402 P194 A226 H227 Q246 S247 F258 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 20519496 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 3abo B 2.1 BS01 B12 B 1 R141 R206 V207 E228 R229 Y241 E253 R256 C258 S260 R98 R163 V164 E185 R186 Y198 E210 R213 C215 S217 4.3.1.7 0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P19636 20519496 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 3abo C 2.1 BS02 B12 D 1 P194 A226 Q246 S247 E257 F258 S295 F329 I330 M401 L402 P194 A226 Q246 S247 E257 F258 S295 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 20519496 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 3abo D 2.1 BS01 B12 D 1 R141 R206 V207 E228 R229 Y241 E253 R256 C258 S260 R98 R159 V160 E181 R182 Y194 E206 R209 C211 S213 4.3.1.7 0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P19636 20519496 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCEAVEALKVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 3abq A 2.05 BS02 B12 B 1 P194 A226 Q246 S247 F258 F329 I330 M401 L402 P194 A226 Q246 S247 F258 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 20519496 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 3abq B 2.05 BS01 B12 B 1 R141 R206 V207 E228 R229 Y241 E253 R256 S260 R98 R163 V164 E185 R186 Y198 E210 R213 S217 4.3.1.7 0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P19636 20519496 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 3abq C 2.05 BS02 B12 D 1 S247 E257 F258 S295 F329 I330 M401 L402 S247 E257 F258 S295 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 20519496 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 3abq D 2.05 BS01 B12 D 1 R141 R206 V207 E228 R229 Y241 E253 R256 S260 R98 R159 V160 E181 R182 Y194 E206 R209 S213 4.3.1.7 0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P19636 20519496 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCEAVEALKVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 3abr A 2.1 BS01 B12 B 1 P194 S247 F258 S295 F329 I330 M401 L402 P194 S247 F258 S295 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 20519496 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 3abr B 2.1 BS01 B12 B 1 R141 L169 R206 V207 K208 E228 R229 Y241 E253 R256 C258 S260 R98 L126 R163 V164 K165 E185 R186 Y198 E210 R213 C215 S217 4.3.1.7 0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P19636 20519496 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 3abr C 2.1 BS01 B12 D 1 S247 E257 F258 F329 I330 L402 S247 E257 F258 F329 I330 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 20519496 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 3abr D 2.1 BS01 B12 D 1 R141 R206 V207 E228 R229 Y241 E253 R256 C258 S260 R98 R163 V164 E185 R186 Y198 E210 R213 C215 S217 4.3.1.7 0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P19636 20519496 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 3any A 2.1 BS02 B12 B 1 P194 A226 H227 Q246 S247 E257 F258 S295 F329 I330 M401 L402 P194 A226 H227 Q246 S247 E257 F258 S295 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 21142024 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 3any B 2.1 BS01 B12 B 1 R141 R206 V207 E228 R229 Y241 E253 R256 C258 S260 R98 R163 V164 E185 R186 Y198 E210 R213 C215 S217 4.3.1.7 0006520,0008851 P19636 21142024 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 3any C 2.1 BS02 B12 D 1 A226 Q246 S247 E257 F258 I330 M401 L402 A226 Q246 S247 E257 F258 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 21142024 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 3any D 2.1 BS01 B12 D 1 R141 L169 R206 V207 E228 R229 Y241 E253 R256 C258 S260 R98 L126 R163 V164 E185 R186 Y198 E210 R213 C215 S217 4.3.1.7 0006520,0008851 P19636 21142024 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 3ao0 A 2.25 BS02 B12 B 1 P194 A226 H227 Q246 S247 E257 F258 S295 F329 I330 M401 L402 P194 A226 H227 Q246 S247 E257 F258 S295 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 21142024 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 3ao0 B 2.25 BS01 B12 B 1 R141 R206 V207 E228 R229 Y241 E253 R256 C258 S260 R98 R163 V164 E185 R186 Y198 E210 R213 C215 S217 4.3.1.7 0006520,0008851 P19636 21142024 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 3ao0 C 2.25 BS02 B12 D 1 P194 A226 Q246 S247 E257 F258 S295 F329 I330 M401 L402 P194 A226 Q246 S247 E257 F258 S295 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 21142024 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 3ao0 D 2.25 BS01 B12 D 1 R141 L169 R206 V207 E228 R229 Y241 E253 R256 C258 S260 R98 L126 R163 V164 E185 R186 Y198 E210 R213 C215 S217 4.3.1.7 0006520,0008851 P19636 21142024 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 3auj A 2.1 BS03 B12 B 1 T172 V173 S202 E205 Q267 M268 S301 M373 F374 T172 V173 S202 E205 Q267 M268 S301 M373 F374 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Km=1.2+-0.2mM (22221669) Q59470 22221669 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNE 3auj B 2.1 BS01 B12 B 1 D112 K135 T137 L148 L153 P155 Q156 A157 P158 Y196 S200 D67 K90 T92 L103 L108 P110 Q111 A112 P113 Y151 S155 4.2.1.28 0016829,0050215 Q59471 22221669 1601 GFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 3auj E 2.1 BS01 B12 E 1 D112 K135 T137 L148 L153 P155 Q156 A157 P158 Y196 S200 D68 K91 T93 L104 L109 P111 Q112 A113 P114 Y152 S156 4.2.1.28 0016829,0050215 Q59471 22221669 2601 DGFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 3auj L 2.1 BS03 B12 E 1 T172 V173 S202 E205 S224 Q267 M268 S301 M373 F374 T172 V173 S202 E205 S224 Q267 M268 S301 M373 F374 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Km=1.2+-0.2mM (22221669) Q59470 22221669 2601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 3bul A 2.3 BS01 B12 A 1 H759 V766 G802 L803 S804 L806 I807 T808 G833 G834 Q858 N859 A860 T863 M952 D1093 A1136 P1137 G1138 Y1139 H1145 K1148 M1171 G1174 V1177 S1178 H109 V116 G152 L153 S154 L156 I157 T158 G183 G184 Q208 N209 A210 T213 M302 D443 A486 P487 G488 Y489 H495 K498 M521 G524 V527 S528 D757 H759 S810 D107 H109 S160 2.1.1.13 0008705,0009086,0031419,0046872 P13009 18332423 1301 QAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPCEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEQCKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYARRKGMSVTEVERWLAPNLGYDAD 3ci1 A 1.9 BS01 B12 A 1 K2 Y31 F67 G70 H71 H82 K2 Y31 F67 G70 H71 H82 2.5.1.17 0005515,0005524,0008817,0009236,0016740,0046872 Q50EJ2 18452306 800 VKIYTKNGDKGQTRIIGKQILYKNDPRVAAYGEVDELNSWVGYTKSLINSHTQVLSNELEEIQQLLFDCGHDLATPADDERHSFKFKQEQPTVWLEEKIDNYTQVVPAVKKFILPGGTQLASALHVARTITRRAERQIVQLMREEQINQDVLIFINRLSDYFFAAARYANYLEQQPDMLYRNSKDVFR 3ci3 A 1.11 BS02 B12 A 1 K2 I3 T5 I15 I16 G70 H71 H82 K2 I3 T5 I15 I16 G70 H71 H82 2.5.1.17 0005515,0005524,0008817,0009236,0016740,0046872 Q50EJ2 18452306 800 VKIYTKNGDKGQTRIIGKQILYKNDPRVAAYGEVDELNSWVGYTKSLINSHTQVLSNELEEIQQLLFDCGHDLATPADDERHSFKFKQEQPTVWLEEKIDNYTQVVPAVKKFILPGGTQLASALHVARTITRRAERQIVQLMREEQINQDVLIFINRLSDYFFAAARYANYLEQQPDMLYRNSKDVFR 3gah A 1.17 BS02 B12 A 1 K2 D35 F67 G70 H71 K1 D34 F66 G69 H70 2.5.1.17 0005515,0005524,0008817,0009236,0016740,0046872 Q50EJ2 19236001 800 KIYTKNGDKGQTRIIGKQILYKNDPRVAAYGEVDELNSWVGYTKSLINSHTQVLSNELEEIQQLLFDCGHDLATPADDERHSFKFKQEQPTVWLEEKIDNYTQVVPAVKKHILPGGTQLASALHVARTITRRAERQIVQLMREEQINQDVLIFINRLSDYFFAAARYANYLEQQPDMLYRNSKDVF 3gai A 1.48 BS02 B12 A 1 K111 A112 I113 R128 R132 S159 D160 F163 K110 A111 I112 R127 R131 S158 D159 F162 2.5.1.17 0005515,0005524,0008817,0009236,0016740,0046872 Q50EJ2 19236001 800 KIYTKNGDKGQTRIIGKQILYKNDPRVAAYGEVDELNSWVGYTKSLINSHTQVLSNELEEIQQLLFDCGHDLATPADDERHSFKFKQEQPTVWLEEKIDNYTQVVPAVKKAILPGGTQLASALHVARTITRRAERQIVQLMREEQINQDVLIFINRLSDYFFAAARYANYLEQQPDMLYRN 3gaj A 1.38 BS02 B12 A 1 I3 F67 G70 H71 I2 F66 G69 H70 2.5.1.17 0005515,0005524,0008817,0009236,0016740,0046872 Q50EJ2 19236001 800 KIYTKNGDKGQTRIIGKQILYKNDPRVAAYGEVDELNSWVGYTKSLINSHTQVLSNELEEIQQLLFDCGHDLATPADDERHSFKFKQEQPTVWLEEKIDNYTQVVPAVKKFILPGGTQLASALHVARTITRRAERQIVQLMREEQINQDVLIFINRLSDYFFAAARYANYLEQQPDMLYR 3iv9 A 3.25 BS01 B12 A 1 V758 H759 I761 G762 I765 G802 S804 L806 T808 G833 G834 A835 V857 Q858 N859 A860 D1093 P1137 G1138 Y1139 H1145 M1171 G1174 A1175 S1176 V1177 S1178 V108 H109 I111 G112 I115 G152 S154 L156 T158 G183 G184 A185 V207 Q208 N209 A210 D443 P487 G488 Y489 H495 M521 G524 A525 S526 V527 S528 D757 H759 S810 D107 H109 S160 2.1.1.13 0008705,0009086,0031419,0046872 P13009 19846791 1301 QAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPCEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEQCKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYARRKGMSVTEVERWLAPNLGYDAD 3iva A 2.7 BS01 B12 A 1 H759 G762 V766 G802 L803 S804 L806 I807 T808 G833 G834 Q858 N859 T953 D1093 A1136 G1138 Y1139 H1145 A1170 M1171 G1174 V1177 S1178 H109 G112 V116 G152 L153 S154 L156 I157 T158 G183 G184 Q208 N209 T303 D443 A486 G488 Y489 H495 A520 M521 G524 V527 S528 D757 H759 S810 D107 H109 S160 2.1.1.13 0008705,0009086,0031419,0046872 P13009 19846791 1301 QAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPCEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEQCKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYARRKGMSVTEVERWLAPNLGYDA 3kow A 2.9 BS01 B12 A 1 E617 H618 S619 V620 G621 L622 V625 A666 S667 I669 I670 S671 G701 G702 T703 F719 G720 S723 E605 H606 S607 V608 G609 L610 V613 A654 S655 I657 I658 S659 G689 G690 T691 F707 G708 S711 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREM 3kow A 2.9 BS03 B12 C 1 Y116 D490 Y112 D483 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREM 3kow B 2.9 BS01 B12 B 1 E617 H618 S619 V620 G621 L622 I669 G701 G702 T703 F719 S723 E605 H606 S607 V608 G609 L610 I657 G689 G690 T691 F707 S711 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kow C 2.9 BS02 B12 C 1 D616 E617 H618 S619 L622 V625 S667 I670 S671 G701 G702 T703 F719 G720 S723 V728 D604 E605 H606 S607 L610 V613 S655 I658 S659 G689 G690 T691 F707 G708 S711 V716 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREM 3kow D 2.9 BS02 B12 B 1 Y116 D490 Y112 D483 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREM 3kow D 2.9 BS03 B12 D 1 E617 H618 V620 G621 V625 A666 S667 I669 I670 H672 G701 G702 T703 F719 G720 S723 V728 E605 H606 V608 G609 V613 A654 S655 I657 I658 H660 G689 G690 T691 F707 G708 S711 V716 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREM 3kox A 2.4 BS01 B12 A 1 E617 H618 S619 V620 G621 A666 S667 I669 S671 G701 G702 T703 F719 G720 G722 S723 E605 H606 S607 V608 G609 A654 S655 I657 S659 G689 G690 T691 F707 G708 G710 S711 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kox A 2.4 BS03 B12 C 1 Y116 D490 Y112 D483 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kox B 2.4 BS01 B12 B 1 E617 H618 S619 V620 G621 L622 A666 S667 I670 S671 G701 G702 T703 F719 G720 S723 E605 H606 S607 V608 G609 L610 A654 S655 I658 S659 G689 G690 T691 F707 G708 S711 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kox C 2.4 BS01 B12 C 1 E617 H618 S619 V620 G621 V625 L665 A666 S667 I669 I670 S671 G701 G702 T703 F719 G720 S723 E605 H606 S607 V608 G609 V613 L653 A654 S655 I657 I658 S659 G689 G690 T691 F707 G708 S711 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kox D 2.4 BS01 B12 D 1 E617 H618 S619 V620 G621 A666 S667 I669 I670 G701 G702 T703 F719 G720 E605 H606 S607 V608 G609 A654 S655 I657 I658 G689 G690 T691 F707 G708 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3koy A 2.8 BS01 B12 A 1 E617 H618 S619 V620 V625 S667 I670 S671 G701 G702 T703 F719 G722 S723 E605 H606 S607 V608 V613 S655 I658 S659 G689 G690 T691 F707 G710 S711 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3koy A 2.8 BS03 B12 C 1 Y116 D490 Y112 D483 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3koy B 2.8 BS02 B12 B 1 D616 E617 H618 S619 G621 L622 L665 A666 S667 I670 S671 G701 G702 T703 F719 G720 S723 D604 E605 H606 S607 G609 L610 L653 A654 S655 I658 S659 G689 G690 T691 F707 G708 S711 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3koy C 2.8 BS02 B12 C 1 E617 H618 S619 V620 G621 L622 I669 I670 S671 G701 G702 T703 F719 G720 G722 S723 V728 E605 H606 S607 V608 G609 L610 I657 I658 S659 G689 G690 T691 F707 G708 G710 S711 V716 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3koy D 2.8 BS01 B12 B 1 Y116 D490 Y112 D483 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3koy D 2.8 BS02 B12 D 1 E617 H618 S619 V620 G621 V625 A666 S667 I669 S671 G701 G702 T703 G720 S723 E605 H606 S607 V608 G609 V613 A654 S655 I657 S659 G689 G690 T691 G708 S711 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3koz A 2.8 BS01 B12 A 1 E617 H618 S619 V620 G621 V625 S667 I669 I670 S671 H672 G701 G702 T703 F719 G720 G722 S723 E605 H606 S607 V608 G609 V613 S655 I657 I658 S659 H660 G689 G690 T691 F707 G708 G710 S711 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3koz A 2.8 BS03 B12 C 1 Y116 D490 Y112 D483 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3koz B 2.8 BS02 B12 B 1 D616 E617 H618 S619 G621 L622 L665 A666 S667 S671 H672 G701 G702 T703 F719 G720 S723 D604 E605 H606 S607 G609 L610 L653 A654 S655 S659 H660 G689 G690 T691 F707 G708 S711 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3koz B 2.8 BS03 B12 D 1 Y116 I127 Y112 I123 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3koz C 2.8 BS02 B12 C 1 E617 H618 S619 V620 G621 L622 I669 I670 S671 G701 G702 T703 F719 G720 S723 V728 E605 H606 S607 V608 G609 L610 I657 I658 S659 G689 G690 T691 F707 G708 S711 V716 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3koz D 2.8 BS01 B12 D 1 E617 H618 S619 G621 A666 S667 I669 S671 G701 G702 T703 F719 G720 G722 S723 E605 H606 S607 G609 A654 S655 I657 S659 G689 G690 T691 F707 G708 G710 S711 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kp0 B 2.8 BS01 B12 B 1 E617 H618 S619 V620 G621 A666 S667 I669 I670 S671 H672 G701 G702 T703 F719 G720 S723 V728 E605 H606 S607 V608 G609 A654 S655 I657 I658 S659 H660 G689 G690 T691 F707 G708 S711 V716 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kp0 C 2.8 BS01 B12 C 1 E617 H618 V620 G621 L622 A666 S667 I669 I670 S671 G701 G702 T703 F719 G720 S723 E605 H606 V608 G609 L610 A654 S655 I657 I658 S659 G689 G690 T691 F707 G708 S711 Y187 H225 R297 K629 Y183 H218 R290 K617 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kp1 A 2.01 BS01 B12 A 1 E617 H618 S619 V620 G621 L622 V625 A666 S667 I669 I670 S671 G701 G702 T703 F719 G720 S723 E603 H604 S605 V606 G607 L608 V611 A652 S653 I655 I656 S657 G687 G688 T689 F705 G706 S709 Y187 H225 R297 K629 Y181 H216 R288 K615 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kp1 B 2.01 BS01 B12 B 1 E617 H618 S619 V620 G621 A666 S667 I669 I670 S671 G701 G702 T703 F719 G720 S723 E603 H604 S605 V606 G607 A652 S653 I655 I656 S657 G687 G688 T689 F705 G706 S709 Y187 H225 R297 K629 Y181 H216 R288 K615 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kp1 B 2.01 BS03 B12 D 1 Y116 I127 Y110 I121 Y187 H225 R297 K629 Y181 H216 R288 K615 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kp1 C 2.01 BS02 B12 C 1 E617 H618 S619 V620 G621 A666 S667 I669 I670 S671 G701 G702 T703 F719 G720 S723 E603 H604 S605 V606 G607 A652 S653 I655 I656 S657 G687 G688 T689 F705 G706 S709 Y187 H225 R297 K629 Y181 H216 R288 K615 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kp1 D 2.01 BS02 B12 D 1 E617 H618 S619 V620 G621 V625 A666 S667 I669 I670 S671 G701 G702 T703 F719 G720 S723 E603 H604 S605 V606 G607 V611 A652 S653 I655 I656 S657 G687 G688 T689 F705 G706 S709 Y187 H225 R297 K629 Y181 H216 R288 K615 5.4.3.5 0003824,0016853,0031419,0046872,0046983,0047831 E3PY95 20106986 1801 LRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMR 3kq4 A 3.3 BS01 B12 A 1 G90 H91 S130 Y133 D171 Y224 S225 S365 W366 G367 V369 V370 W386 F388 L395 N396 E397 G398 Y417 G66 H67 S106 Y109 D147 Y200 S201 S333 W334 G335 V337 V338 W354 F356 L363 N364 E365 G366 Y385 ? 0005515,0005576,0005615,0005768,0005902,0006824,0015889,0016324,0031419,0043202,0140355 P27352 20237569 2007 SCSVPSAQEPLVNGIQVLMENSVTSSAYPNPSILIAMNLAGAYNLKAQKLLTYQLMSSDNNDLTIGHLGLTIMALTSSCRDPGDKVSILQRQMENWAPSSPNAEASAFYGPSLAILALCQKNSEATLPIAVRFAKTLLANSSPFNVDTGAMATLALTCMYNKIPVGSEEGYRSLFGQVLKDIVEKISMKIKDNGIIGDIYSTGLAMQALSVTPEPSKKEWNCKKTTDMILNEIKQGKFHNPMSIAQILPSLKGKTYLDVPQVTCSPDHEVQPTLPSASNITVIYTINNQLRGVELLFNETINVSVKSGSVLLVVLEEAQRKNPMFKFETTMTSWGLVVSSINNIAENVNHKTYWQFLSGVTPLNEGVADYIPFNHEHITANFTQY 3kq4 C 3.3 BS01 B12 C 1 G90 H91 S130 Y133 D171 Y224 S225 S365 W366 G367 V369 V370 W386 F388 L395 N396 E397 G398 Y417 G66 H67 S106 Y109 D147 Y200 S201 S333 W334 G335 V337 V338 W354 F356 L363 N364 E365 G366 Y385 ? 0005515,0005576,0005615,0005768,0005902,0006824,0015889,0016324,0031419,0043202,0140355 P27352 20237569 2007 SCSVPSAQEPLVNGIQVLMENSVTSSAYPNPSILIAMNLAGAYNLKAQKLLTYQLMSSDNNDLTIGHLGLTIMALTSSCRDPGDKVSILQRQMENWAPSSPNAEASAFYGPSLAILALCQKNSEATLPIAVRFAKTLLANSSPFNVDTGAMATLALTCMYNKIPVGSEEGYRSLFGQVLKDIVEKISMKIKDNGIIGDIYSTGLAMQALSVTPEPSKKEWNCKKTTDMILNEIKQGKFHNPMSIAQILPSLKGKTYLDVPQVTCSPDHEVQPTLPSASNITVIYTINNQLRGVELLFNETINVSVKSGSVLLVVLEEAQRKNPMFKFETTMTSWGLVVSSINNIAENVNHKTYWQFLSGVTPLNEGVADYIPFNHEHITANFTQY 3kq4 E 3.3 BS01 B12 E 1 G90 H91 S130 Y133 D171 Y224 S225 S365 W366 G367 V369 V370 W386 F388 L395 N396 E397 G398 Y417 G66 H67 S106 Y109 D147 Y200 S201 S333 W334 G335 V337 V338 W354 F356 L363 N364 E365 G366 Y385 ? 0005515,0005576,0005615,0005768,0005902,0006824,0015889,0016324,0031419,0043202,0140355 P27352 20237569 2007 SCSVPSAQEPLVNGIQVLMENSVTSSAYPNPSILIAMNLAGAYNLKAQKLLTYQLMSSDNNDLTIGHLGLTIMALTSSCRDPGDKVSILQRQMENWAPSSPNAEASAFYGPSLAILALCQKNSEATLPIAVRFAKTLLANSSPFNVDTGAMATLALTCMYNKIPVGSEEGYRSLFGQVLKDIVEKISMKIKDNGIIGDIYSTGLAMQALSVTPEPSKKEWNCKKTTDMILNEIKQGKFHNPMSIAQILPSLKGKTYLDVPQVTCSPDHEVQPTLPSASNITVIYTINNQLRGVELLFNETINVSVKSGSVLLVVLEEAQRKNPMFKFETTMTSWGLVVSSINNIAENVNHKTYWQFLSGVTPLNEGVADYIPFNHEHITANFTQY 3o0n B 1.95 BS03 B12 B 1 R26 N242 G294 G492 S502 F508 T598 T626 V627 Y628 R26 N229 G281 G479 S489 F495 T576 T604 V605 Y606 C134 N320 C322 E324 C333 T626 V627 C134 N307 C309 E311 C320 T604 V605 1.17.4.1 0000166,0004748,0005524,0009263,0031419 O33839 20672854 1003 MKLSDLISRWIDVEPSKNAQIILRDRYFMKDLDGNYLETKWEDVARRVARVVATAELLNPSYKKNEKLDRIKEWEDIFFRVLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEEIYRSRNHLHMLSACFVVPVGDSIEEIFEAVKEYALITKVGGGVGSNFSELRPKGSFVAGTHGKASGPVSFMHVFNSAISVVKALMGILNINHPDIEEFIDAKKVLNFFNLSVGFPMDKKEILKLYEEDGELELSHPRSTIRKKVKIRELFRKIATNAWKSGDPGLAFLGEMNKYYPLYPHRKINSTNPCGEIGLSDYEACNLGSIDVAKFYNNGFVDLEALQELVQIAVRFLDNVIDVNVFPIDKITKAVKESRRLGLGIMGFADLLYKLEIPYNSQEARDFAANLMAFIALHAHRTSYELGKEKGNFPLLEISRYRTEDNFVPFAMGMSNYDDEIREVMKMTKEFRRNVALLTIAPTGSISNIADTSSGLEPNFLLAYTRFPLLYVNQVLREKLNPEILKRIEKELIEKGSLKDIPDVPEKIKKVFVVALDIDPMDHLLMQDAFQRYVDNNISKTINMPQSATVDDVLNVYLEALRTNVRGITVYRDGSL 3o0o A 1.9 BS03 B12 A 1 R208 G492 N496 F508 T598 N600 Y628 R202 G480 N484 F496 T577 N579 Y607 C134 N320 C322 E324 C333 T626 V627 C129 N308 C310 E312 C321 T605 V606 1.17.4.1 0000166,0004748,0005524,0009263,0031419 O33839 20672854 1004 MKLSDLISRWIDVEPSKNAQIILRDRYFMKDLDGNYLETKWEDVARRVARVVATAELLNPSKLDRIKEWEDIFFRVLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEEIYRSRNHLHMLSACFVVPVGDSIEEIFEAVKEYALITKVGGGVGSNFSELRPKGSFVAGTHGKASGPVSFMHVFNSAISVVKQGSRRGALMGILNINHPDIEEFIDAKKVLNFFNLSVGFPMDKKEILKLYEEDGELELSHPRSTIRKKVKIRELFRKIATNAWKSGDPGLAFLGEMNKYYPLYPHRKINSTNPCGEIGLSDYEACNLGSIDVAKFYNNGFVDLEALQELVQIAVRFLDNVIDVNVFPIDKITKAVKESRRLGLGIMGFADLLYKLEIPYNSQEARDFAANLMAFIALHAHRTSYELGKEKGNFPLLEISRYRTEDNFVPFAMGMSNYDDEIREVMKMTKEFRRNVALLTIAPTGSISNIADTSSGLEPNFLLAYTRFPLLYVNQVLREKLNPEILKRIEKELIEKGSLKDIPDVPEKIKKVFVVALDIDPMDHLLMQDAFQRYVDNNISKTINMPQSATVDDVLNVYLEALRTNVRGITVYRDGSL 3o0o B 1.9 BS04 B12 B 1 R206 R208 D295 C322 G492 N496 F508 N600 Y628 R206 R208 D289 C316 G486 N490 F502 N585 Y613 C134 N320 C322 E324 C333 T626 V627 C134 N314 C316 E318 C327 T611 V612 1.17.4.1 0000166,0004748,0005524,0009263,0031419 O33839 20672854 1004 MKLSDLISRWIDVEPSKNAQIILRDRYFMKDLDGNYLETKWEDVARRVARVVATAELLNPSYKKNEKLDRIKEWEDIFFRVLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEEIYRSRNHLHMLSACFVVPVGDSIEEIFEAVKEYALITKVGGGVGSNFSELRPKGSFVAGTHGKASGPVSFMHVFNSAISVVKQGSRRRGALMGILNINHPDIEEFIDAKKVLNFFNLSVGFPMDKKEILKLYEEDGELELSHPRSTIRKKVKIRELFRKIATNAWKSGDPGLAFLGEMNKYYPLYPHRKINSTNPCGEIGLSDYEACNLGSIDVAKFYNNGFVDLEALQELVQIAVRFLDNVIDVNVFPIDKITKAVKESRRLGLGIMGFADLLYKLEIPYNSQEARDFAANLMAFIALHAHRTSYELGKEKGNFPLLEISRYRTEDNFVPFAMGMSNYDDEIREVMKMTKEFRRNVALLTIAPTGSISNIADTSSGLEPNFLLAYTRFPLLYVNQVLREKLNPEILKRIEKELIEKGSLKDIPDVPEKIKKVFVVALDIDPMDHLLMQDAFQRYVDNNISKTINMPQSATVDDVLNVYLEALRTNVRGITVYRDGSL 3req A 2.7 BS01 B12 A 1 L119 V206 R207 E247 G333 W334 A371 G609 H610 D611 R612 G613 I617 G653 S655 L657 G685 G686 Y705 T706 P707 T709 L116 V203 R204 E244 G330 W331 A368 G606 H607 D608 R609 G610 I614 G650 S652 L654 G682 G683 Y702 T703 P704 T706 Y89 Y243 H244 K604 D608 H610 Y86 Y240 H241 K601 D605 H607 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 9655823 800 LPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 3som A 2.4 BS01 B12 A 1 L34 L35 P36 D104 P113 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L31 L32 P33 D101 P110 A114 Q115 H119 Y126 Q128 R141 S143 C146 I157 F193 W197 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 KVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQR 3som B 2.4 BS01 B12 B 1 L34 L35 P36 D104 P113 A117 Q118 T119 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L32 L33 P34 D102 P111 A115 Q116 T117 H120 Y127 Q129 R142 S144 C147 I158 F194 W198 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 PKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQR 3som C 2.4 BS01 B12 C 1 L34 L35 P36 D104 P113 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L31 L32 P33 D101 P110 A114 Q115 H119 Y126 Q128 R141 S143 C146 I157 F193 W197 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 KVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRL 3som D 2.4 BS01 B12 D 1 L34 L35 P36 D104 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L33 L34 P35 D103 A116 Q117 H121 Y128 Q130 R143 S145 C148 I159 F195 W199 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 EPKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQR 3som E 2.4 BS01 B12 E 1 L34 L35 P36 D104 P113 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L31 L32 P33 D101 P110 A114 Q115 H119 Y126 Q128 R141 S143 C146 I157 F193 W197 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 KVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRLAL 3som F 2.4 BS01 B12 F 1 L34 L35 P36 D104 P113 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L32 L33 P34 D102 P111 A115 Q116 H120 Y127 Q129 R142 S144 C147 I158 F194 W198 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 PKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQR 3som G 2.4 BS01 B12 G 1 L34 L35 P36 D104 P113 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L32 L33 P34 D102 P111 A115 Q116 H120 Y127 Q129 R142 S144 C147 I158 F194 W198 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 PKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQR 3som H 2.4 BS01 B12 H 1 L34 L35 P36 D104 P113 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L31 L32 P33 D101 P110 A114 Q115 H119 Y126 Q128 R141 S143 C146 I157 F193 W197 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 KVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQR 3som I 2.4 BS01 B12 I 1 L34 L35 P36 D104 P113 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L32 L33 P34 D102 P111 A115 Q116 H120 Y127 Q129 R142 S144 C147 I158 F194 W198 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 PKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQR 3som J 2.4 BS01 B12 J 1 L34 L35 P36 D104 P113 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L31 L32 P33 D101 P110 A114 Q115 H119 Y126 Q128 R141 S143 C146 I157 F193 W197 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 KVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQR 3som K 2.4 BS01 B12 K 1 L34 L35 P36 D104 P113 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L31 L32 P33 D101 P110 A114 Q115 H119 Y126 Q128 R141 S143 C146 I157 F193 W197 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 KVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQR 3som L 2.4 BS01 B12 L 1 L34 L35 P36 D104 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L32 L33 P34 D102 A115 Q116 H120 Y127 Q129 R142 S144 C147 I158 F194 W198 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 PKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRLAL 3som M 2.4 BS01 B12 M 1 L34 L35 P36 D104 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L33 L34 P35 D103 A116 Q117 H121 Y128 Q130 R143 S145 C148 I159 F195 W199 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 EPKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRLA 3som N 2.4 BS01 B12 N 1 L34 L35 P36 D104 P113 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L31 L32 P33 D101 P110 A114 Q115 H119 Y126 Q128 R141 S143 C146 I157 F193 W197 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 KVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRLALLG 3som O 2.4 BS01 B12 O 1 L34 L35 P36 D104 P113 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L31 L32 P33 D101 P110 A114 Q115 H119 Y126 Q128 R141 S143 C146 I157 F193 W197 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 KVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRL 3som P 2.4 BS01 B12 P 1 L34 L35 P36 D104 P113 A117 Q118 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L33 L34 P35 D103 P112 A116 Q117 H121 Y128 Q130 R143 S145 C148 I159 F195 W199 1.16.1.6,2.5.1.151 0005515,0005737,0005829,0006749,0009235,0016491,0016740,0016765,0031419,0032451,0033787,0042803,0043295,0055114,0070988,0071949 Q9Y4U1 22642810 301 EPKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRL 3whp A 2.52 BS01 B12 A 1 G128 W131 H132 E141 R176 H177 E178 G180 S222 G247 G248 M264 D266 L267 G48 W51 H52 E61 R96 H97 E98 G100 S142 G167 G168 M184 D186 L187 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 800 EDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAE 4c1n A 2.53 BS02 B12 I 1 F337 I338 T339 F342 T345 C348 V349 T370 S371 V372 L373 T374 P407 P429 R430 S432 F336 I337 T338 F341 T344 C347 V348 T369 S370 V371 L372 T373 P406 P428 R429 S431 ? 0005506,0008168,0044237,0046356,0046872,0051536,0051539 Q3ACS3 25109607 1631 GLTGLEIYKHLPKKNCKECGQPTCLAFAMQIAAGKAGLDACPYVSDEAKELLESASAPPVALIKVGKGEKVLEIGHETVLFRHDKRFEHPCGLAILVEDTLSEGEIKERVEKINKLVFDRVGQMHSVNLVALKGSSQDAATFAKAVATAREVTDLPFILIGTPEQLAAALETEGANNPLLYAATADNYEQMVELAKKYNVPLTVSAKGLDALAELVQKITALGYKNLILDPQPENISEGLFYQTQIRRLAIKKLFRPFGYPTIAFALDENPYQAVMEASVYIAKYAGIIVLNTVEPADILPLITLRLNIYTDPQKPIAVEPKVYEILNPGPDAPVFITTNFSLTYFCVAGDVEGARIPAYILPVDTDGTSVLTAWAAGKFTPEKIAQFLKESGIAEKVNHRKAILPGGVAVLSGKLQELSGWEILVGPRESSGINSFIKQRW 4c1n C 2.53 BS01 B12 C 1 F337 T339 F342 T345 V349 T370 S371 V372 L373 T374 I405 P407 P429 R430 S432 F336 T338 F341 T344 V348 T369 S370 V371 L372 T373 I404 P406 P428 R429 S431 ? 0005506,0008168,0044237,0046356,0046872,0051536,0051539 Q3ACS3 25109607 1444 GLTGLEIYKHLPKKNCKECGQPTCLAFAMQIAAGKAGLDACPYVSDEAKELLESASAPPVALIKVGKGEKVLEIGHETVLFRHDKRFEHPCGLAILVEDTLSEGEIKERVEKINKLVFDRVGQMHSVNLVALKGSSQDAATFAKAVATAREVTDLPFILIGTPEQLAAALETEGANNPLLYAATADNYEQMVELAKKYNVPLTVSAKGLDALAELVQKITALGYKNLILDPQPENISEGLFYQTQIRRLAIKKLFRPFGYPTIAFALDENPYQAVMEASVYIAKYAGIIVLNTVEPADILPLITLRLNIYTDPQKPIAVEPKVYEILNPGPDAPVFITTNFSLTYFCVAGDVEGARIPAYILPVDTDGTSVLTAWAAGKFTPEKIAQFLKESGIAEKVNHRKAILPGGVAVLSGKLQELSGWEILVGPRESSGINSFIKQRW 4c1n E 2.53 BS02 B12 X 1 I338 T339 F342 T345 C348 V349 T370 S371 V372 L373 T374 P407 P429 R430 S432 I337 T338 F341 T344 C347 V348 T369 S370 V371 L372 T373 P406 P428 R429 S431 ? 0005506,0008168,0044237,0046356,0046872,0051536,0051539 Q3ACS3 25109607 1631 GLTGLEIYKHLPKKNCKECGQPTCLAFAMQIAAGKAGLDACPYVSDEAKELLESASAPPVALIKVGKGEKVLEIGHETVLFRHDKRFEHPCGLAILVEDTLSEGEIKERVEKINKLVFDRVGQMHSVNLVALKGSSQDAATFAKAVATAREVTDLPFILIGTPEQLAAALETEGANNPLLYAATADNYEQMVELAKKYNVPLTVSAKGLDALAELVQKITALGYKNLILDPQPENISEGLFYQTQIRRLAIKKLFRPFGYPTIAFALDENPYQAVMEASVYIAKYAGIIVLNTVEPADILPLITLRLNIYTDPQKPIAVEPKVYEILNPGPDAPVFITTNFSLTYFCVAGDVEGARIPAYILPVDTDGTSVLTAWAAGKFTPEKIAQFLKESGIAEKVNHRKAILPGGVAVLSGKLQELSGWEILVGPRESSGINSFIKQRW 4c1n G 2.53 BS02 B12 K 1 I338 T339 T345 V349 T370 S371 V372 L373 T374 P407 P429 R430 S432 I336 T337 T343 V347 T368 S369 V370 L371 T372 P405 P427 R428 S430 ? 0005506,0008168,0044237,0046356,0046872,0051536,0051539 Q3ACS3 25109607 1631 LTGLEIYKHLPKKNCKECGQPTCLAFAMQIAAGKAGLDACPYVSDEAKELLESASAPPVALIKVGKGEKVLEIGHETVLFRHDKRFEHPCGLAILVEDTLSEGEIKERVEKINKLVFDRVGQMHSVNLVALKGSSQDAATFAKAVATAREVTDLPFILIGTPEQLAAALETEGANNPLLYAATADNYEQMVELAKKYNVPLTVSAKGLDALAELVQKITALGYKNLILDPQPENISEGLFYQTQIRRLAIKKLFRPFGYPTIAFALDENPYQAVMEASVYIAKYAGIIVLNTVEPADILPLITLRLNIYTDPQKPIAVEPKVYEILNPGPDAPVFITTNFSLTYFCVAGDVEGARIPAYILPVDTDGTSVLTAWAAGKFTPEKIAQFLKESGIAEKVNHRKAILPGGVAVLSGKLQELSGWEILVGPRESSGINSFIKQRW 4c1n I 2.53 BS01 B12 I 1 D246 I248 Y318 Y352 N381 S398 A399 N509 R512 F609 M610 F613 D125 I127 Y197 Y231 N260 S277 A278 N388 R391 F488 M489 F492 ? Q3ACS2 25109607 1631 LDPLFKEVSLELPVPTLDDPRDDLSRLTATFSRQENGNLIVEYEQLKDLPQILRNENFSVTVGVSDYLGLNKALYIKSGSASQRVFGLAIDIGTTTVVVQLVDLVSGKVLGTKGNYNKQAAFGDDVISRIIYVDENPDGAEKLRKAVLSTINELIFQLCKEHGVEKKEIMAAVVAGNTTMTHLFLEIDPRYIRLEPYTPAALFIPPVPATEAKIEMNPKGFVYIMPNVASYVGGDITSGVLYTGLANSDEITLFIDIGTNGEMVLGNKDWLVTCACSAGPAFEGSGIKHGMRAMQGAIERVSISEAGLKVKYQTVGGIPPVGICGSGLIDLLANLKRAGIIDRSGKIDRTVNKERIREGEDGLEFVLAWANESGNNKDIVITEADIQNLIRAKAAIFAGVRTMLAMVDLPLEAIDRVIIAGGFGKYLNIKDAITIGLLPDIDINKFSYVGNSSLKGARKALLSRKACAEVKEIARKMTYLELSVGTTFMDEFVSASFIPHTDLHLFPSV 4c1n J 2.53 BS01 B12 C 1 D246 I248 Y318 Y352 S398 A399 G400 R512 F609 M610 F613 D125 I127 Y197 Y231 S277 A278 G279 R391 F488 M489 F492 ? Q3ACS2 25109607 1444 LDPLFKEVSLELPVPTLDDPRDDLSRLTATFSRQENGNLIVEYEQLKDLPQILRNENFSVTVGVSDYLGLNKALYIKSGSASQRVFGLAIDIGTTTVVVQLVDLVSGKVLGTKGNYNKQAAFGDDVISRIIYVDENPDGAEKLRKAVLSTINELIFQLCKEHGVEKKEIMAAVVAGNTTMTHLFLEIDPRYIRLEPYTPAALFIPPVPATEAKIEMNPKGFVYIMPNVASYVGGDITSGVLYTGLANSDEITLFIDIGTNGEMVLGNKDWLVTCACSAGPAFEGSGIKHGMRAMQGAIERVSISEAGLKVKYQTVGGIPPVGICGSGLIDLLANLKRAGIIDRSGKIDRTVNKERIREGEDGLEFVLAWANESGNNKDIVITEADIQNLIRAKAAIFAGVRTMLAMVDLPLEAIDRVIIAGGFGKYLNIKDAITIGLLPDIDINKFSYVGNSSLKGARKALLSRKACAEVKEIARKMTYLELSVGTTFMDEFVSASFIPHTDLHLFPSV 4c1n K 2.53 BS01 B12 K 1 I248 Y318 Y352 N381 S398 A399 G400 N509 R512 F609 M610 F613 I128 Y198 Y232 N261 S278 A279 G280 N389 R392 F489 M490 F493 ? Q3ACS2 25109607 1631 ELDPLFKEVSLELPVPTLDDPRDDLSRLTATFSRQENGNLIVEYEQLKDLPQILRNENFSVTVGVSDYLGLNKALYIKSGSASQRVFGLAIDIGTTTVVVQLVDLVSGKVLGTKGNYNKQAAFGDDVISRIIYVDENPDGAEKLRKAVLSTINELIFQLCKEHGVEKKEIMAAVVAGNTTMTHLFLEIDPRYIRLEPYTPAALFIPPVPATEAKIEMNPKGFVYIMPNVASYVGGDITSGVLYTGLANSDEITLFIDIGTNGEMVLGNKDWLVTCACSAGPAFEGSGIKHGMRAMQGAIERVSISEAGLKVKYQTVGGIPPVGICGSGLIDLLANLKRAGIIDRSGKIDRTVNKERIREGEDGLEFVLAWANESGNNKDIVITEADIQNLIRAKAAIFAGVRTMLAMVDLPLEAIDRVIIAGGFGKYLNIKDAITIGLLPDIDINKFSYVGNSSLKGARKALLSRKACAEVKEIARKMTYLELSVGTTFMDEFVSASFIPHTDLHLFPSV 4c1n X 2.53 BS01 B12 X 1 D246 Y318 Y352 N381 S398 A399 P401 N509 R512 S604 F609 M610 F613 D125 Y197 Y231 N260 S277 A278 P280 N388 R391 S483 F488 M489 F492 ? Q3ACS2 25109607 1631 LDPLFKEVSLELPVPTLDDPRDDLSRLTATFSRQENGNLIVEYEQLKDLPQILRNENFSVTVGVSDYLGLNKALYIKSGSASQRVFGLAIDIGTTTVVVQLVDLVSGKVLGTKGNYNKQAAFGDDVISRIIYVDENPDGAEKLRKAVLSTINELIFQLCKEHGVEKKEIMAAVVAGNTTMTHLFLEIDPRYIRLEPYTPAALFIPPVPATEAKIEMNPKGFVYIMPNVASYVGGDITSGVLYTGLANSDEITLFIDIGTNGEMVLGNKDWLVTCACSAGPAFEGSGIKHGMRAMQGAIERVSISEAGLKVKYQTVGGIPPVGICGSGLIDLLANLKRAGIIDRSGKIDRTVNKERIREGEDGLEFVLAWANESGNNKDIVITEADIQNLIRAKAAIFAGVRTMLAMVDLPLEAIDRVIIAGGFGKYLNIKDAITIGLLPDIDINKFSYVGNSSLKGARKALLSRKACAEVKEIARKMTYLELSVGTTFMDEFVSASFIPHTDLHLFPSV 4djd C 2.38 BS02 B12 C 1 P318 T340 T346 V350 L371 S372 V373 T375 A378 D379 G429 P430 R431 E432 A433 P317 T339 T345 V349 L370 S371 V372 T374 A377 D378 G428 P429 R430 E431 A432 ? 0005506,0005515,0008168,0015977,0031419,0044237,0046356,0046872,0051536,0051539 Q07340 22419154 502 PLTGLEIYKQLPKKNCGECGTPTCLAFAMNLASGKASLDSCPYVSDAAREALDAAAAPPIAKVVLGAGPTAVEMGDETELFRHDKRFYHETAIAIQVSDNLSSEELKAKVEAINGLNFDRVGQHYTIQAIAIRHDADDPAAFKAAVASVAAATQLNLVLMADDPDVLKEALAGVADRKPLLYAATGANYEAMTALAKENNCPLAVYGNGLEELAELVDKIVALGHKQLVLDPGARETSRAIADFTQIRRLAIKKRFRSFGYPIIALTTAANPLDEVLQAVNYVTKYASLVVLRTDAKEHLLPLLSWRQNLYTDPQVPIRVEEKLNEIGAVNENSPVYVTTNFSLTYYSVEGEIESTKIPSYLLSVDTDGLSVLTAYADGKFEAEKIAAVMKKVDLDNKVKRHRIIIPGAVAVLKGKLEDLTGWEVIVGPREASGIVAFARA 4djd D 2.38 BS01 B12 C 1 P188 Y226 P188 Y226 ? 0005515,0006730,0015977,0031419,0044237 Q07341 22419154 502 MAVQILRDRSRAAVQKVVLGATKDQGGTRSHTIVVGGDAALPFHHFEGEIVNRPVIGMEVQDIVPDWPDVLKDPFTDVINEPGRWAQKCVAEYGADLIYLKLDGADPEGANHSVDQCVATVKEVLQAVGVPLVVVGCGDVEKDHEVLEAVAEAAAGENLLLGNAEQENYKSLTAACMVHKHNIIARSPLDINICKQLNILINEMNLPLDHIVIDPSIGGLGYGIEYSFSIMERIRLGALQGDKMLSMPVICTVGYEAWRAKEASAPVSEYPGWGKETERGILWEAVTATALLQAGAHILLMRHPEAVARVKENIDQLMVSNAY 4djd E 2.38 BS02 B12 E 1 P318 Y338 T340 T346 L371 S372 V373 T375 A378 D379 P408 P430 A433 P317 Y337 T339 T345 L370 S371 V372 T374 A377 D378 P407 P429 A432 ? 0005506,0005515,0008168,0015977,0031419,0044237,0046356,0046872,0051536,0051539 Q07340 22419154 502 PLTGLEIYKQLPKKNCGECGTPTCLAFAMNLASGKASLDSCPYVSDAAREALDAAAAPPIAKVVLGAGPTAVEMGDETELFRHDKRFYHETAIAIQVSDNLSSEELKAKVEAINGLNFDRVGQHYTIQAIAIRHDADDPAAFKAAVASVAAATQLNLVLMADDPDVLKEALAGVADRKPLLYAATGANYEAMTALAKENNCPLAVYGNGLEELAELVDKIVALGHKQLVLDPGARETSRAIADFTQIRRLAIKKRFRSFGYPIIALTTAANPLDEVLQAVNYVTKYASLVVLRTDAKEHLLPLLSWRQNLYTDPQVPIRVEEKLNEIGAVNENSPVYVTTNFSLTYYSVEGEIESTKIPSYLLSVDTDGLSVLTAYADGKFEAEKIAAVMKKVDLDNKVKRHRIIIPGAVAVLKGKLEDLTGWEVIVGPREASGIVAFARA 4djd F 2.38 BS01 B12 E 1 P188 L189 P188 L189 ? 0005515,0006730,0015977,0031419,0044237 Q07341 22419154 502 MAVQILRDRSRAAVQKVVLGATKDQGGTRSHTIVVGGDAALPFHHFEGEIVNRPVIGMEVQDIVPDWPDVLKDPFTDVINEPGRWAQKCVAEYGADLIYLKLDGADPEGANHSVDQCVATVKEVLQAVGVPLVVVGCGDVEKDHEVLEAVAEAAAGENLLLGNAEQENYKSLTAACMVHKHNIIARSPLDINICKQLNILINEMNLPLDHIVIDPSIGGLGYGIEYSFSIMERIRLGALQGDKMLSMPVICTVGYEAWRAKEASAPVSEYPGWGKETERGILWEAVTATALLQAGAHILLMRHPEAVARVKENIDQLMVSNAY 4dje A 3.504 BS03 B12 E 1 V168 N203 V168 N203 2.1.1.258 0005509,0005515,0005829,0008168,0008705,0009086,0015977,0031419,0032259,0042558,0044237,0046872,0102036 Q46389 22419154 502 MLIIGERINGMFGDIKRAIQERDPAPVQEWARRQEEGGARALDLNVGPAVQDKVSAMEWLVEVTQEVSNLTLCLDSTNIKAIEAGLKKCKNRAMINSTNAEREKVEKLFPLAVEHGAALIGLTMNKTGIPKDSDTRLAFAMELVAAADEFGLPMEDLYIDPLILPANVAQDHAPEVLKTLQQIKMLADPAPKTVLGLSNVSQNCQNRPLINRTFLAMAMACGLDAAIADACDEALIETAATAEILLNQTVYCDSFVKMFKTR 4dje B 3.504 BS02 B12 C 1 N199 N203 N199 N203 2.1.1.258 0005509,0005515,0005829,0008168,0008705,0009086,0015977,0031419,0032259,0042558,0044237,0046872,0102036 Q46389 22419154 502 MLIIGERINGMFGDIKRAIQERDPAPVQEWARRQEEGGARALDLNVGPAVQDKVSAMEWLVEVTQEVSNLTLCLDSTNIKAIEAGLKKCKNRAMINSTNAEREKVEKLFPLAVEHGAALIGLTMNKTGIPKDSDTRLAFAMELVAAADEFGLPMEDLYIDPLILPANVAQDHAPEVLKTLQQIKMLADPAPKTVLGLSNVSQNCQNRPLINRTFLAMAMACGLDAAIADACDEALIETAATAEILLNQTVYCDSFVKMFKTR 4dje C 3.504 BS02 B12 C 1 P318 T340 T346 S372 V373 L374 T375 A378 D379 P408 R431 A433 P317 T339 T345 S371 V372 L373 T374 A377 D378 P407 R430 A432 ? 0005506,0005515,0008168,0015977,0031419,0044237,0046356,0046872,0051536,0051539 Q07340 22419154 502 PLTGLEIYKQLPKKNCGECGTPTCLAFAMNLASGKASLDSCPYVSDAAREALDAAAAPPIAKVVLGAGPTAVEMGDETELFRHDKRFYHETAIAIQVSDNLSSEELKAKVEAINGLNFDRVGQHYTIQAIAIRHDADDPAAFKAAVASVAAATQLNLVLMADDPDVLKEALAGVADRKPLLYAATGANYEAMTALAKENNCPLAVYGNGLEELAELVDKIVALGHKQLVLDPGARETSRAIADFTQIRRLAIKKRFRSFGYPIIALTTAANPLDEVLQAVNYVTKYASLVVLRTDAKEHLLPLLSWRQNLYTDPQVPIRVEEKLNEIGAVNENSPVYVTTNFSLTYYSVEGEIESTKIPSYLLSVDTDGLSVLTAYADGKFEAEKIAAVMKKVDLDNKVKRHRIIIPGAVAVLKGKLEDLTGWEVIVGPREASGIVAFARA 4dje E 3.504 BS02 B12 E 1 P318 T340 F343 L345 T346 S349 V350 S372 P408 P430 R431 A433 P317 T339 F342 L344 T345 S348 V349 S371 P407 P429 R430 A432 ? 0005506,0005515,0008168,0015977,0031419,0044237,0046356,0046872,0051536,0051539 Q07340 22419154 502 PLTGLEIYKQLPKKNCGECGTPTCLAFAMNLASGKASLDSCPYVSDAAREALDAAAAPPIAKVVLGAGPTAVEMGDETELFRHDKRFYHETAIAIQVSDNLSSEELKAKVEAINGLNFDRVGQHYTIQAIAIRHDADDPAAFKAAVASVAAATQLNLVLMADDPDVLKEALAGVADRKPLLYAATGANYEAMTALAKENNCPLAVYGNGLEELAELVDKIVALGHKQLVLDPGARETSRAIADFTQIRRLAIKKRFRSFGYPIIALTTAANPLDEVLQAVNYVTKYASLVVLRTDAKEHLLPLLSWRQNLYTDPQVPIRVEEKLNEIGAVNENSPVYVTTNFSLTYYSVEGEIESTKIPSYLLSVDTDGLSVLTAYADGKFEAEKIAAVMKKVDLDNKVKRHRIIIPGAVAVLKGKLEDLTGWEVIVGPREASGIVAFARA 4hut A 1.95 BS03 B12 A 1 W69 W93 Y131 F184 Y196 W64 W88 Y126 F179 Y191 N37 K39 K41 T42 T43 R51 F91 W93 E128 N32 K34 K36 T37 T38 R46 F86 W88 E123 2.5.1.17 0005524,0005737,0006779,0008817,0009236,0016740 P31570 23148601 203 YQQRQQKVKDRVDARVAQAQEERGIIIVFTGNGKGKTTAAFGTAARAVGHGKNVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWETQNREADTAACMAVWQHGKRMLADPLLDMVVLDELTYMVAYDYLPLEEVISALNARPGHQTVIITGRGCHRDILDLADTVSELRPVKHAFDAGVKAQMGIDY 4hut B 1.95 BS03 B12 B 1 I65 K66 T68 W69 G90 F91 T92 W93 E128 Y131 R161 F184 D195 Y196 I38 K39 T41 W42 G63 F64 T65 W66 E101 Y104 R134 F157 D168 Y169 N37 K39 K41 T42 T43 R51 F91 W93 E128 N10 K12 K14 T15 T16 R24 F64 W66 E101 2.5.1.17 0005524,0005737,0006779,0008817,0009236,0016740 P31570 23148601 203 RGIIIVFTGNGKGKTTAAFGTAARAVGHGKNVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWETQNREADTAACMAVWQHGKRMLADPLLDMVVLDELTYMVAYDYLPLEEVISALNARPGHQTVIITGRGCHRDILDLADTVSELRPVKHAFDAGVKAQMGIDY 4lem A 2.27 BS01 B12 A 1 I186 F246 T269 H272 I187 F247 T270 H273 N190 K212 E293 C327 E425 A510 N191 K213 E294 C328 E426 A511 1.2.1.88 0000166,0003842,0006560,0009898,0010133,0016491,0016620,0046872 O50443 25557497 601 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMA 4lem B 2.27 BS01 B12 B 1 F246 T269 H272 F247 T270 H273 N190 K212 E293 C327 E425 A510 N191 K213 E294 C328 E426 A511 1.2.1.88 0000166,0003842,0006560,0009898,0010133,0016491,0016620,0046872 O50443 25557497 601 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMAV 4lem C 2.27 BS01 B12 C 1 I186 F246 H272 I187 F247 H273 N190 K212 E293 C327 E425 A510 N191 K213 E294 C328 E426 A511 1.2.1.88 0000166,0003842,0006560,0009898,0010133,0016491,0016620,0046872 O50443 25557497 601 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMAVD 4lem D 2.27 BS01 B12 D 1 I186 F246 T269 H272 I187 F247 T270 H273 N190 K212 E293 C327 E425 A510 N191 K213 E294 C328 E426 A511 1.2.1.88 0000166,0003842,0006560,0009898,0010133,0016491,0016620,0046872 O50443 25557497 601 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMAVD 4ns3 A 2.38 BS01 B12 A 1 I186 F246 T269 H272 I187 F247 T270 H273 N190 K212 E293 C327 E425 A510 N191 K213 E294 C328 E426 A511 1.2.1.88 0000166,0003842,0006560,0009898,0010133,0016491,0016620,0046872 O50443 25557497 601 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMA 4ns3 B 2.38 BS01 B12 B 1 F246 T269 H272 R373 F247 T270 H273 R374 N190 K212 E293 C327 E425 A510 N191 K213 E294 C328 E425 A510 1.2.1.88 0000166,0003842,0006560,0009898,0010133,0016491,0016620,0046872 O50443 25557497 601 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMAV 4ns3 C 2.38 BS01 B12 C 1 F246 T269 H272 R373 F247 T270 H273 R374 N190 K212 E293 C327 E425 A510 N191 K213 E294 C328 E426 A511 1.2.1.88 0000166,0003842,0006560,0009898,0010133,0016491,0016620,0046872 O50443 25557497 601 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMAVD 4ns3 D 2.38 BS01 B12 D 1 I186 F246 T269 H272 R373 I187 F247 T270 H273 R374 N190 K212 E293 C327 E425 A510 N191 K213 E294 C328 E426 A511 1.2.1.88 0000166,0003842,0006560,0009898,0010133,0016491,0016620,0046872 O50443 25557497 601 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMAVD 4r3u A 2.5 BS03 B12 C 1 D117 M120 E140 Q208 E210 E248 A335 E372 A373 A375 D116 M119 E139 Q207 E209 E247 A334 E371 A372 A374 I90 Y244 H245 I89 Y243 H244 5.4.99.64 0003824,0004494,0016853,0016866,0031419 I3VE77 25720495 800 TWLEPQIKSQLQSERKDWEANEVGAFLKKAPERKEQFHTIGDFPVQRTYTAADIADTPLEDIGLPGRYPFTRGPYPTMYRSRTWTMRQIAGFGTGEDTNKRFKYLIAQGQTGISTDFDMPTLMGYDSDHPMSDGEVGREGVAIDTLADMEALLADIDLEKISVSFTINPSAWILLAMYVALGEKRGYDLNKLSGTVQADILKEYMAQKEYIYPIAPSVRIVRDIITYSAKNLKRYNPINISGYHISEAGSSPLQEAAFTLANLITYVNEVTKTGMHVDEFAPRLAFFFVSQGDFFEEVAKFRALRRCYAKIMKERFGARNPESMRLRFHCQTAAATLTKPQYMVNVVRTSLQALSAVLGGAQSLHTNGYDEAFAIPTEDAMKMALRTQQIIAEESGVADVIDPLGGSYYVEALTTEYEKKIFEILEEVEKRGGTIKLIEQGWFQKQIADFAYETALRKQSGQKPVIGVNRFVENEEDVKIEIHPYDNTTAERQISRTRRVRAERDEAKVQAMLDQLVAVAKDESQNLMPLTIELVKAGATMGDIVEKLKGIWGTYRE 4r3u B 2.5 BS03 B12 D 1 D117 M120 E140 Q208 E210 H245 E248 A335 E372 A373 A375 D116 M119 E139 Q207 E209 H244 E247 A334 E371 A372 A374 I90 Y244 H245 I89 Y243 H244 5.4.99.64 0003824,0004494,0016853,0016866,0031419 I3VE77 25720495 800 TWLEPQIKSQLQSERKDWEANEVGAFLKKAPERKEQFHTIGDFPVQRTYTAADIADTPLEDIGLPGRYPFTRGPYPTMYRSRTWTMRQIAGFGTGEDTNKRFKYLIAQGQTGISTDFDMPTLMGYDSDHPMSDGEVGREGVAIDTLADMEALLADIDLEKISVSFTINPSAWILLAMYVALGEKRGYDLNKLSGTVQADILKEYMAQKEYIYPIAPSVRIVRDIITYSAKNLKRYNPINISGYHISEAGSSPLQEAAFTLANLITYVNEVTKTGMHVDEFAPRLAFFFVSQGDFFEEVAKFRALRRCYAKIMKERFGARNPESMRLRFHCQTAAATLTKPQYMVNVVRTSLQALSAVLGGAQSLHTNGYDEAFAIPTEDAMKMALRTQQIIAEESGVADVIDPLGGSYYVEALTTEYEKKIFEILEEVEKRGGTIKLIEQGWFQKQIADFAYETALRKQSGQKPVIGVNRFVENEVKIEIHPYDNTTAERQISRTRRVRAERDEAKVQAMLDQLVAVAKDESQNLMPLTIELVKAGATMGDIVEKLKGIWGTYRE 4r3u C 2.5 BS01 B12 C 1 G17 H18 D19 R20 G21 V25 G61 S63 L65 I91 A92 G93 G94 L113 L114 Q115 T117 G15 H16 D17 R18 G19 V23 G59 S61 L63 I89 A90 G91 G92 L111 L112 Q113 T115 K12 D16 H18 K10 D14 H16 5.4.99.64 0016853,0031419,0046872 I3VE74 25720495 800 QTPIRVLLAKVGLDGHDRGVKVVARALRDAGMDVIYSGLHRTPEEVVNTAIQEDVDVLGVSLLSGVQLTVFPKIFKLLDERGAGDLIVIAGGVMPDEDAAAIRKLGVREVLLQDTPPQAIIDSIRSLVAAR 4r3u D 2.5 BS01 B12 D 1 G17 H18 D19 R20 G21 V25 G61 S63 L65 A92 G93 G94 L113 L114 Q115 T117 I122 G14 H15 D16 R17 G18 V22 G58 S60 L62 A89 G90 G91 L110 L111 Q112 T114 I119 K12 D16 H18 K9 D13 H15 5.4.99.64 0016853,0031419,0046872 I3VE74 25720495 800 TPIRVLLAKVGLDGHDRGVKVVARALRDAGMDVIYSGLHRTPEEVVNTAIQEDVDVLGVSLLSGVQLTVFPKIFKLLDERGAGDLIVIAGGVMPDEDAAAIRKLGVREVLLQDTPPQAIIDSIRSLVAA 4ras A 2.3 BS03 B12 A 1 D289 F290 F291 Y379 S422 Y426 I458 H459 N460 I463 I474 D476 T477 L478 K488 S489 F535 Y538 K542 V545 C548 R552 D289 F290 F291 Y379 S422 Y426 I458 H459 N460 I463 I474 D476 T477 L478 K488 S489 F535 Y538 K542 V545 C548 R552 ? 0046872,0051539 K2MB66 25327251 803 MRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSAG 4ras B 2.3 BS03 B12 B 1 D289 F290 F291 Y379 Y426 I458 H459 N460 P461 I463 I474 D476 T477 L478 K488 S489 F535 Y538 K542 T549 R552 C561 D289 F290 F291 Y379 Y426 I458 H459 N460 P461 I463 I474 D476 T477 L478 K488 S489 F535 Y538 K542 T549 R552 C561 ? 0046872,0051539 K2MB66 25327251 803 MRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSA 4ras C 2.3 BS03 B12 C 1 D289 F290 F291 Y379 Y426 I458 H459 N460 P461 I463 I474 D476 T477 L478 K488 S489 F535 Y538 K542 V545 T549 R552 D285 F286 F287 Y375 Y422 I454 H455 N456 P457 I459 I470 D472 T473 L474 K484 S485 F531 Y534 K538 V541 T545 R548 ? 0046872,0051539 K2MB66 25327251 803 MRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSS 4req A 2.2 BS01 B12 A 1 Y89 L119 A139 V206 R207 H244 E247 G333 W334 E370 A371 A373 L374 G609 H610 D611 R612 G613 I617 S655 L657 G685 G686 V687 Y705 T706 T709 Y87 L117 A137 V204 R205 H242 E245 G331 W332 E368 A369 A371 L372 G607 H608 D609 R610 G611 I615 S653 L655 G683 G684 V685 Y703 T704 T707 Y89 Y243 H244 K604 D608 H610 Y87 Y241 H242 K602 D606 H608 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 9655823 800 TLPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 4req C 2.2 BS01 B12 C 1 Y89 L119 A139 R207 H244 E247 G333 W334 E370 A371 A373 L374 G609 H610 D611 R612 G613 I617 Y621 S655 L657 G659 G685 G686 V687 Y705 T706 T709 Y87 L117 A137 R205 H242 E245 G331 W332 E368 A369 A371 L372 G607 H608 D609 R610 G611 I615 Y619 S653 L655 G657 G683 G684 V685 Y703 T704 T707 Y89 Y243 H244 K604 D608 H610 Y87 Y241 H242 K602 D606 H608 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 9655823 800 TLPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 4u6i C 2.1 BS01 B12 C 1 P31 H32 P31 H32 ? 0005198,0031419,0031469,0046872 Q8XLZ0 25484204 301 MKNDLIRPNVLSVKIISNVSPEMAKKLELEPHHKSLGLITADCDDVTYTALDEATKAAEVDVVYARSMYAGAGNASTKLAGEVIGILAGPSPAEVRSGLNATLDFIDSGVGFVSANEDDSICYYAQCVSRTGSYLSKTAGIREGEALAYLVAPPLEAMYALDAALKAADVEMCEFFAPPTETNFAGALLTGSQSACKAACDAFAEAVQSVASNPLG 4xc6 A 3.35 BS01 B12 A 1 G38 H39 D40 A41 S42 M46 Y86 Q87 G114 G116 V118 Y136 S137 P138 M149 F627 L632 S650 Q742 H780 E783 A784 G868 R869 E905 A906 T908 H993 G18 H19 D20 A21 S22 M26 Y66 Q67 G94 G96 V98 Y116 S117 P118 M129 F601 L606 S624 Q716 H754 E757 A758 G842 R843 E879 A880 T882 H967 K26 F598 Y779 H780 K6 F572 Y753 H754 3.6.5.-,5.4.99.13 0000287,0003824,0003924,0004494,0005525,0006637,0016787,0016853,0016866,0031419,0034784,0046872,0047727 Q1LRY0 25675500 1101 RGPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREAGSEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVVIRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGEDPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYDEAITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGDPTPQTLELARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 4xc6 B 3.35 BS01 B12 B 1 H39 D40 A41 S42 Y86 Q87 G114 G116 Y136 S137 M149 Q742 H18 D19 A20 S21 Y65 Q66 G93 G95 Y115 S116 M128 Q720 K26 F598 Y779 H780 K5 F576 Y757 H758 3.6.5.-,5.4.99.13 0000287,0003824,0003924,0004494,0005525,0006637,0016787,0016853,0016866,0031419,0034784,0046872,0047727 Q1LRY0 25675500 1101 GPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREAGSEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVVKIRDKEIRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGDPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYDITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGLARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 5c8a A 2.15 BS01 B12 A 1 L121 R125 G128 E141 S145 G174 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L41 R45 G48 E61 S65 G94 R96 H97 E98 I99 G100 S142 L145 G167 G168 Q169 M184 D186 L187 ? 0031419,0046872 Q746J7 26416754 300 EDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 5c8a B 2.15 BS01 B12 B 1 L121 L124 R125 G128 E141 S145 G174 R176 H177 E178 I179 G180 S222 L225 G247 G248 M264 L267 L39 L42 R43 G46 E59 S63 G92 R94 H95 E96 I97 G98 S140 L143 G165 G166 M182 L185 ? 0031419,0046872 Q746J7 26416754 301 LGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 5c8a C 2.15 BS01 B12 C 1 L124 G128 E141 S145 G174 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L45 G49 E62 S66 G95 R97 H98 E99 I100 G101 S143 L146 G168 G169 Q170 M185 D187 L188 ? 0031419,0046872 Q746J7 26416754 300 PEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 5c8a D 2.15 BS01 B12 D 1 L124 G128 E141 S145 G174 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L44 G48 E61 S65 G94 R96 H97 E98 I99 G100 S142 L145 G167 G168 Q169 M184 D186 L187 ? 0031419,0046872 Q746J7 26416754 300 EDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 5c8d A 2.8 BS01 B12 A 1 L121 L124 G128 E141 S145 G174 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L65 L68 G72 E85 S89 G118 R120 H121 E122 I123 G124 S166 L169 G191 G192 Q193 M208 D210 L211 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 EDVEALKTIKRWLEEIRRYLAVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW 5c8d B 2.8 BS01 B12 B 1 L121 L124 G128 E141 R176 H177 E178 I179 G180 L183 S222 L225 G247 G248 Q249 M264 D266 L267 L66 L69 G73 E86 R121 H122 E123 I124 G125 L128 S167 L170 G192 G193 Q194 M209 D211 L212 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 VEALKTIKRWPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 5c8d C 2.8 BS01 B12 C 1 L121 R125 G128 W131 E141 S145 R176 H177 E178 G180 L183 S222 V224 L225 G247 G248 Q249 M264 D266 L267 L69 R73 G76 W79 E89 S93 R124 H125 E126 G128 L131 S170 V172 L173 G195 G196 Q197 M212 D214 L215 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 LKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW 5c8d D 2.8 BS01 B12 D 1 R125 G128 E141 H142 S145 G174 R176 H177 E178 G180 S222 L225 G247 G248 M264 D266 L267 R122 G125 E138 H139 S142 G171 R173 H174 E175 G177 S219 L222 G244 G245 M261 D263 L264 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 SGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 5c8d E 2.8 BS01 B12 E 1 L121 R125 G128 E141 S145 G174 R176 H177 E178 G180 S222 L225 G247 G248 M264 D266 L267 L118 R122 G125 E138 S142 G171 R173 H174 E175 G177 S219 L222 G244 G245 M261 D263 L264 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 SGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRGPEKE 5c8d F 2.8 BS01 B12 F 1 L121 G128 E141 S145 R176 H177 E178 G180 L183 S222 L225 G247 G248 M264 D266 L267 L115 G122 E135 S139 R170 H171 E172 G174 L177 S216 L219 G241 G242 M258 D260 L261 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 5c8d G 2.8 BS01 B12 G 1 L121 L124 R125 G128 W131 H132 E141 S145 R176 H177 E178 G180 S222 V224 L225 G247 G248 Q249 M264 L267 L108 L111 R112 G115 W118 H119 E128 S132 R163 H164 E165 G167 S209 V211 L212 G234 G235 Q236 M251 L254 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 SGVYTIAEVEAMTGLSAEVLRQWERRYGFPKYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 5c8d H 2.8 BS01 B12 H 1 L124 R125 G128 E141 H142 R176 H177 E178 I179 L183 S222 L225 G247 G248 M264 D266 L267 L124 R125 G128 E141 H142 R176 H177 E178 I179 L183 S222 L225 G247 G248 M264 D266 L267 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 LVPRGSHMTSVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLP 5c8e A 3.89 BS04 B12 A 1 L121 L124 G128 E141 G174 R176 H177 E178 G180 S222 L225 G247 G248 M264 L267 L117 L120 G124 E137 G170 R172 H173 E174 G176 S218 L221 G243 G244 M260 L263 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLP 5c8e B 3.89 BS03 B12 B 1 L121 L124 G128 E141 G174 R176 H177 E178 G180 S222 L225 G247 G248 Q249 M264 L267 L117 L120 G124 E137 G170 R172 H173 E174 G176 S218 L221 G243 G244 Q245 M260 L263 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRGP 5c8e C 3.89 BS03 B12 C 1 L121 L124 G128 E141 G174 R176 H177 E178 G180 S222 L225 G247 G248 Q249 M264 L267 L122 L125 G129 E142 G175 R177 H178 E179 G181 S223 L226 G248 G249 Q250 M265 L268 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 HMTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 5c8e D 3.89 BS01 B12 D 1 L121 L124 G128 E141 G174 R176 H177 E178 G180 S222 L225 G247 G248 Q249 M264 L267 L46 L49 G53 E66 G99 R101 H102 E103 G105 S147 L150 G172 G173 Q174 M189 L192 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 QEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRGP 5c8e E 3.89 BS03 B12 E 1 L124 G128 E141 G174 R176 H177 E178 G180 S222 L225 G247 G248 M264 L267 L119 G123 E136 G169 R171 H172 E173 G175 S217 L220 G242 G243 M259 L262 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 VYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 5c8e F 3.89 BS02 B12 F 1 L121 L124 G128 E141 G174 R176 H177 E178 G180 S222 L225 G247 G248 Q249 M264 L267 L112 L115 G119 E132 G165 R167 H168 E169 G171 S213 L216 G238 G239 Q240 M255 L258 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 VYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRG 5c8e G 3.89 BS03 B12 G 1 L121 L124 G128 E141 G174 R176 H177 E178 G180 S222 L225 G247 G248 Q249 M264 L267 L122 L125 G129 E142 G175 R177 H178 E179 G181 S223 L226 G248 G249 Q250 M265 L268 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 HMTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRG 5c8e H 3.89 BS01 B12 H 1 L121 L124 G128 E141 G174 R176 H177 E178 G180 S222 L225 G247 G248 Q249 M264 L45 L48 G52 E65 G98 R100 H101 E102 G104 S146 L149 G171 G172 Q173 M188 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 300 EVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLP 5c8f A 2.65 BS01 B12 A 1 R125 G128 W131 H132 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 R121 G124 W127 H128 R172 H173 E174 I175 G176 S218 L221 G243 G244 Q245 M260 D262 L263 ? 0003677,0003700,0006355,0031419,0042802,0046872 Q746J7 26416754 301 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 5cjt A 3.4 BS01 B12 A 1 G38 H39 D40 A41 S42 M46 Y86 Q87 G114 G116 V118 Y136 S137 F627 L632 S650 Q742 H780 E783 A784 G868 R869 E905 A906 T908 H993 G18 H19 D20 A21 S22 M26 Y66 Q67 G94 G96 V98 Y116 S117 F598 L603 S621 Q713 H751 E754 A755 G839 R840 E876 A877 T879 H964 K26 F598 Y779 H780 K6 F569 Y750 H751 3.6.5.-,5.4.99.13 0000287,0003824,0003924,0004494,0005525,0006637,0016787,0016853,0016866,0031419,0034784,0046872,0047727 Q1LRY0 26318610 1101 RGPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREASEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGEDPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYDEAITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGDPQTLELARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 5cjt B 3.4 BS01 B12 B 1 H39 D40 A41 S42 M46 Y86 Q87 G114 G116 Y136 S137 G141 M149 Q742 H18 D19 A20 S21 M25 Y65 Q66 G93 G95 Y115 S116 G120 M128 Q720 K26 F598 Y779 H780 K5 F576 Y757 H758 3.6.5.-,5.4.99.13 0000287,0003824,0003924,0004494,0005525,0006637,0016787,0016853,0016866,0031419,0034784,0046872,0047727 Q1LRY0 26318610 1101 GPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREAGSEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVVKIRDKEIRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGDPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGLARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 5cju A 3.5 BS01 B12 A 1 G38 H39 D40 A41 S42 M46 Y86 Q87 G114 G116 V118 Y136 S137 M149 F627 L632 S650 Q742 Y779 H780 E783 A784 G868 R869 E905 A906 T908 H993 G18 H19 D20 A21 S22 M26 Y66 Q67 G94 G96 V98 Y116 S117 M129 F599 L604 S622 Q714 Y751 H752 E755 A756 G840 R841 E877 A878 T880 H965 K26 F598 Y779 H780 K6 F570 Y751 H752 3.6.5.-,5.4.99.13 0000287,0003824,0003924,0004494,0005525,0006637,0016787,0016853,0016866,0031419,0034784,0046872,0047727 Q1LRY0 26318610 1101 RGPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREASEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVIRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGEDPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYDEAITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGDPTQTLELARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 5cju B 3.5 BS01 B12 B 1 H39 D40 A41 S42 M46 Y86 Q87 G114 G116 Y136 S137 G141 M149 Q742 H18 D19 A20 S21 M25 Y65 Q66 G93 G95 Y115 S116 G120 M128 Q719 K26 F598 Y779 H780 K5 F575 Y756 H757 3.6.5.-,5.4.99.13 0000287,0003824,0003924,0004494,0005525,0006637,0016787,0016853,0016866,0031419,0034784,0046872,0047727 Q1LRY0 26318610 1101 GPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREAGSEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVVKIRDKEIRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYDITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGLARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 5cjv A 3.45 BS01 B12 A 1 G38 H39 D40 A41 S42 M46 Y86 Q87 G114 G116 V118 Y136 S137 M149 F627 L632 S650 Q742 E783 A784 G868 R869 E905 A906 T908 H993 G18 H19 D20 A21 S22 M26 Y66 Q67 G94 G96 V98 Y116 S117 M129 F598 L603 S621 Q713 E754 A755 G839 R840 E876 A877 T879 H964 K26 F598 Y779 H780 K6 F569 Y750 H751 3.6.5.-,5.4.99.13 0000287,0003824,0003924,0004494,0005525,0006637,0016787,0016853,0016866,0031419,0034784,0046872,0047727 Q1LRY0 26318610 1101 RGPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATRESEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVIRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGEDPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYDEAITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGDQTLELARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 5cjv B 3.45 BS01 B12 B 1 H39 D40 A41 S42 Y86 Q87 G114 G116 Y136 S137 M149 Q742 H18 D19 A20 S21 Y65 Q66 G93 G95 Y115 S116 M128 Q719 K26 F598 Y779 H780 K5 F575 Y756 H757 3.6.5.-,5.4.99.13 0000287,0003824,0003924,0004494,0005525,0006637,0016787,0016853,0016866,0031419,0034784,0046872,0047727 Q1LRY0 26318610 1101 GPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREAGSEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVVKIRDKEIRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGLARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 5cjw A 3.4 BS01 B12 A 1 G38 H39 D40 A41 S42 M46 Y86 Q87 G114 G116 V118 Y136 S137 P138 F627 L632 S650 Q742 H780 E783 A784 G868 R869 E905 A906 T908 H993 G18 H19 D20 A21 S22 M26 Y66 Q67 G94 G96 V98 Y116 S117 P118 F600 L605 S623 Q715 H753 E756 A757 G841 R842 E878 A879 T881 H966 K26 F598 Y779 H780 K6 F571 Y752 H753 3.6.5.-,5.4.99.13 0000287,0003824,0003924,0004494,0005525,0006637,0016787,0016853,0016866,0031419,0034784,0046872,0047727 Q1LRY0 26318610 1101 RGPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREAGSEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVIRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGEDPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYDEAITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGDQTLELARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 5cjw B 3.4 BS01 B12 B 1 H39 D40 A41 S42 Y86 Q87 G114 G116 Y136 S137 Q742 H18 D19 A20 S21 Y65 Q66 G93 G95 Y115 S116 Q719 K26 F598 Y779 H780 K5 F575 Y756 H757 3.6.5.-,5.4.99.13 0000287,0003824,0003924,0004494,0005525,0006637,0016787,0016853,0016866,0031419,0034784,0046872,0047727 Q1LRY0 26318610 1101 GPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREAGSEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVVKIRDKEIRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYDITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGLARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 5d08 A 1.747 BS03 B12 A 1 R36 F49 E50 R57 C97 D134 S139 D140 R141 A142 S152 M157 I158 V167 L169 L209 S216 F217 G239 C240 R35 F48 E49 R56 C96 D133 S138 D139 R140 A141 S151 M156 I157 V166 L168 L208 S215 F216 G238 C239 1.17.99.6 0005737,0006400,0008033,0008616,0016491,0046872,0051536,0051539,0052693 P97030 27638883 503 NVYQLKEELIEYAKSIGVDKIGFTTADTFDSLKDRLILQESLGYLSGFEEPDIEKRVTPKLLLPKAKSIVAIALAYPSRMKDAPRSTRTERRGIFCRASWGKDYHDVLREKLDLLEDFLKSKHEDIRTKSMVDTGELSDRAVAERAGIGFSAKNCMITTPEYGSYVYLAEMITNIPFEPDVPIEDMCGSCTKCLDACPTGALVNPGQLNAQRCISFLTQTKGFLPDEFRTKIGNRLYGCDTCQTVCPLNKGKDFHLHPEMEPDPEIAKPLLKPLLAISNREFKEKFGHVSGSWRGKKPIQRNAILALAHFKDASALPELTELMHKDPRPVIRGTAAWAIGKIGDPAYAEELEKALEKEKDEEAKLEIEKGIELLKASGMTKQGL 5d08 B 1.747 BS03 B12 B 1 R36 F49 E50 R57 C97 D134 S139 D140 R141 A142 S152 M157 I158 V167 L169 L209 S216 F217 G239 C240 R35 F48 E49 R56 C96 D133 S138 D139 R140 A141 S151 M156 I157 V166 L168 L208 S215 F216 G238 C239 1.17.99.6 0005737,0006400,0008033,0008616,0016491,0046872,0051536,0051539,0052693 P97030 27638883 503 NVYQLKEELIEYAKSIGVDKIGFTTADTFDSLKDRLILQESLGYLSGFEEPDIEKRVTPKLLLPKAKSIVAIALAYPSRMKDAPRSTRTERRGIFCRASWGKDYHDVLREKLDLLEDFLKSKHEDIRTKSMVDTGELSDRAVAERAGIGFSAKNCMITTPEYGSYVYLAEMITNIPFEPDVPIEDMCGSCTKCLDACPTGALVNPGQLNAQRCISFLTQTKGFLPDEFRTKIGNRLYGCDTCQTVCPLNKGKDFHLHPEMEPDPEIAKPLLKPLLAISNREFKEKFGHVSGSWRGKKPIQRNAILALAHFKDASALPELTELMHKDPRPVIRGTAAWAIGKIGDPAYAEELEKALEKEKDEEAKLEIEKGIELLK 5d0a A 2.1 BS05 B12 A 1 R36 S47 F49 E50 R57 C97 Y105 D134 S139 D140 R141 A142 S152 M157 I158 V167 L169 L209 S216 F217 G239 C240 R35 S46 F48 E49 R56 C96 Y104 D132 S137 D138 R139 A140 S150 M155 I156 V165 L167 L207 S214 F215 G237 C238 1.17.99.6 0005737,0006400,0008033,0008616,0016491,0046872,0051536,0051539,0052693 P97030 27638883 503 NVYQLKEELIEYAKSIGVDKIGFTTADTFDSLKDRLILQESLGYLSGFEEPDIEKRVTPKLLLPKAKSIVAIALAYPSRMKDAPRSTRTERRGIFCRASWGKDYHDVLREKLDLLEDFLKSKHDIRTKSMVDTGELSDRAVAERAGIGFSAKNCMITTPEYGSYVYLAEMITNIPFEPDVPIEDMCGSCTKCLDACPTGALVNPGQLNAQRCISFLTQTKGFLPDEFRTKIGNRLYGCDTCQTVCPLNKGKDFHLHPEMEPDPEIAKPLLKPLLAISNREFKEKFGHVSGSWRGKKPIQRNAILALAHFKDASALPELTELMHKDPRPVIRGTAAWAIGKIGDPAYAEELEKALEKEKDEEAKLEIEKGIELLKASGMT 5d0a B 2.1 BS04 B12 B 1 R36 F49 E50 R57 C97 D134 S139 D140 R141 S152 M157 I158 V167 L169 G207 L209 S216 F217 G239 C240 R35 F48 E49 R56 C96 D132 S137 D138 R139 S150 M155 I156 V165 L167 G205 L207 S214 F215 G237 C238 1.17.99.6 0005737,0006400,0008033,0008616,0016491,0046872,0051536,0051539,0052693 P97030 27638883 503 NVYQLKEELIEYAKSIGVDKIGFTTADTFDSLKDRLILQESLGYLSGFEEPDIEKRVTPKLLLPKAKSIVAIALAYPSRMKDAPRSTRTERRGIFCRASWGKDYHDVLREKLDLLEDFLKSKHDIRTKSMVDTGELSDRAVAERAGIGFSAKNCMITTPEYGSYVYLAEMITNIPFEPDVPIEDMCGSCTKCLDACPTGALVNPGQLNAQRCISFLTQTKGFLPDEFRTKIGNRLYGCDTCQTVCPLNKGKDFHLHPEMEPDPEIAKPLLKPLLAISNREFKEKFGHVSGSWRGKKPIQRNAILALAHFKDASALPELTELMHKDPRPVIRGTAAWAIGKIGDPAYAEELEKALEKEKDEEAKLEIEKGIELLKASGMT 5d0a C 2.1 BS03 B12 C 1 R36 F49 E50 R57 C97 D134 S139 D140 R141 A142 S152 N155 M157 I158 V167 L169 G207 L209 S216 F217 G239 C240 R35 F48 E49 R56 C96 D132 S137 D138 R139 A140 S150 N153 M155 I156 V165 L167 G205 L207 S214 F215 G237 C238 1.17.99.6 0005737,0006400,0008033,0008616,0016491,0046872,0051536,0051539,0052693 P97030 27638883 503 NVYQLKEELIEYAKSIGVDKIGFTTADTFDSLKDRLILQESLGYLSGFEEPDIEKRVTPKLLLPKAKSIVAIALAYPSRMKDAPRSTRTERRGIFCRASWGKDYHDVLREKLDLLEDFLKSKHDIRTKSMVDTGELSDRAVAERAGIGFSAKNCMITTPEYGSYVYLAEMITNIPFEPDVPIEDMCGSCTKCLDACPTGALVNPGQLNAQRCISFLTQTKGFLPDEFRTKIGNRLYGCDTCQTVCPLNKGKDFHLHPEMEPDPEIAKPLLKPLLAISNREFKEKFGHVSGSWRGKKPIQRNAILALAHFKDASALPELTELMHKDPRPVIRGTAAWAIGKIGDPAYAEELEKALEKEKDEEAKLEIEKGIELLKAS 5d0a D 2.1 BS03 B12 D 1 R36 E50 R57 C97 D134 S139 D140 R141 A142 S152 M157 I158 V167 L169 G207 L209 S216 F217 G239 C240 R35 E49 R56 C96 D132 S137 D138 R139 A140 S150 M155 I156 V165 L167 G205 L207 S214 F215 G237 C238 1.17.99.6 0005737,0006400,0008033,0008616,0016491,0046872,0051536,0051539,0052693 P97030 27638883 503 NVYQLKEELIEYAKSIGVDKIGFTTADTFDSLKDRLILQESLGYLSGFEEPDIEKRVTPKLLLPKAKSIVAIALAYPSRMKDAPRSTRTERRGIFCRASWGKDYHDVLREKLDLLEDFLKSKHDIRTKSMVDTGELSDRAVAERAGIGFSAKNCMITTPEYGSYVYLAEMITNIPFEPDVPIEDMCGSCTKCLDACPTGALVNPGQLNAQRCISFLTQTKGFLPDEFRTKIGNRLYGCDTCQTVCPLNKGKDFHLHPEMEPDPEIAKPLLKPLLAISNREFKEKFGHVSGSWRGKKPIQRNAILALAHFKDASALPELTELMHKDPRPVIRGTAAWAIGKIGDPAYAEELEKALEKEKDEEAKLEIEKGIELLKA 5d0b A 2.645 BS04 B12 A 1 R36 R57 C97 D134 S139 D140 R141 A142 S152 M157 I158 L169 G207 L209 S216 F217 G239 C240 R35 R56 C96 D133 S138 D139 R140 A141 S151 M156 I157 L168 G206 L208 S215 F216 G238 C239 1.17.99.6 0005737,0006400,0008033,0008616,0016491,0046872,0051536,0051539,0052693 P97030 27638883 503 NVYQLKEELIEYAKSIGVDKIGFTTADTFDSLKDRLILQESLGYLSGFEEPDIEKRVTPKLLLPKAKSIVAIALAYPSRMKDAPRSTRTERRGIFCRASWGKDYHDVLREKLDLLEDFLKSKHEDIRTKSMVDTGELSDRAVAERAGIGFSAKNCMITTPEYGSYVYLAEMITNIPFEPDVPIEDMCGSCTKCLDACPTGALVNPGQLNAQRCISFLTQTKGFLPDEFRTKIGNRLYGCDTCQTVCPLNKGKDFHLHPEMEPDPEIAKPLLKPLLAISNREFKEKFGHVSGSWRGKKPIQRNAILALAHFKDASALPELTELMHKDPRPVIRGTAAWAIGKIGDPAYAEELEKALEKEKDEEAKLEIEKGIELLKA 5d0b B 2.645 BS03 B12 B 1 R36 F49 E50 R57 C97 Y105 D134 S139 D140 R141 A142 S152 M157 I158 V167 L169 G207 L209 S216 G239 C240 R35 F48 E49 R56 C96 Y104 D132 S137 D138 R139 A140 S150 M155 I156 V165 L167 G205 L207 S214 G237 C238 1.17.99.6 0005737,0006400,0008033,0008616,0016491,0046872,0051536,0051539,0052693 P97030 27638883 503 NVYQLKEELIEYAKSIGVDKIGFTTADTFDSLKDRLILQESLGYLSGFEEPDIEKRVTPKLLLPKAKSIVAIALAYPSRMKDAPRSTRTERRGIFCRASWGKDYHDVLREKLDLLEDFLKSKHDIRTKSMVDTGELSDRAVAERAGIGFSAKNCMITTPEYGSYVYLAEMITNIPFEPDVPIEDMCGSCTKCLDACPTGALVNPGQLNAQRCISFLTQTKGFLPDEFRTKIGNRLYGCDTCQTVCPLNKGKDFHLHPEMEPDPEIAKPLLKPLLAISNREFKEKFGHVSGSWRGKKPIQRNAILALAHFKDASALPELTELMHKDPRPVIRGTAAWAIGKIGDPAYAEELEKALEKEKDEEAKLEIEKGIELLKA 5d6s A 2.65 BS03 B12 A 1 T44 R54 N95 D130 V135 D136 T137 I148 G152 L153 V154 M163 L165 T204 M205 S212 C236 T44 R54 N95 D130 V135 D136 T137 I148 G152 L153 V154 M163 L165 T204 M205 S212 C236 ? 0005737,0008033,0008616,0016491,0046872,0051539,0052693 A0A0R4I997 26378237 403 MNIKLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5d6s B 2.65 BS03 B12 B 1 T44 R54 N95 D130 D136 T137 I148 G152 L153 V154 M163 L165 G203 T204 M205 S212 G235 C236 T44 R54 N95 D130 D136 T137 I148 G152 L153 V154 M163 L165 G203 T204 M205 S212 G235 C236 ? 0005737,0008033,0008616,0016491,0046872,0051539,0052693 A0A0R4I997 26378237 403 MNIKLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5d6s C 2.65 BS03 B12 C 1 Y29 L30 T44 R54 T93 N95 D130 D136 T137 K141 I148 G152 L153 V154 M163 L165 D202 G203 T204 M205 C210 S212 G235 C236 Y26 L27 T41 R51 T90 N92 D127 D133 T134 K138 I145 G149 L150 V151 M160 L162 D199 G200 T201 M202 C207 S209 G232 C233 ? 0005737,0008033,0008616,0016491,0046872,0051539,0052693 A0A0R4I997 26378237 403 KLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5d6s D 2.65 BS03 B12 D 1 Y29 L30 T44 R54 T93 N95 D130 L134 D136 T137 I148 G152 V154 M163 L165 D202 G203 T204 M205 S212 C236 Y29 L30 T44 R54 T93 N95 D130 L134 D136 T137 I148 G152 V154 M163 L165 D202 G203 T204 M205 S212 C236 ? 0005737,0008033,0008616,0016491,0046872,0051539,0052693 A0A0R4I997 26378237 403 MNIKLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5d6s E 2.65 BS03 B12 E 1 Y29 L30 L34 T44 R54 T93 N95 D130 D136 T137 K141 I148 G152 V154 M163 L165 T204 M205 S212 C236 Y29 L30 L34 T44 R54 T93 N95 D130 D136 T137 K141 I148 G152 V154 M163 L165 T204 M205 S212 C236 ? 0005737,0008033,0008616,0016491,0046872,0051539,0052693 A0A0R4I997 26378237 403 MNIKLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5laa A 3.0 BS01 B12 A 1 G16 D17 Y18 A29 V30 I47 G49 P50 K52 T53 N55 G57 K60 V61 Q82 H84 A110 I111 G16 D17 Y18 A29 V30 I47 G49 P50 K52 T53 N55 G57 K60 V61 Q82 H84 A110 I111 2.1.1.86 0005886,0006730,0006814,0008168,0015948,0019386,0030269,0032259,0050897 E3GWY7 27324530 201 MVKKKEPAEGWPVVSGDYIVGDPESPVAAVTLASHIEDIPIDAGAAIAGPCKTENLGIEKVIANIISNPNIRFLVLCGSEVQGHIVGQSMKALHKNGVDDKRKIIGAKGAIPYIENLPEEALERFQKQVEIVDLIDVEDADQIKEKVKECIEKDPGAFEEE 5laa B 3.0 BS01 B12 B 1 G16 D17 Y18 A29 V30 G49 P50 K52 T53 N55 G57 K60 V61 Q82 G83 H84 A110 G15 D16 Y17 A28 V29 G48 P49 K51 T52 N54 G56 K59 V60 Q81 G82 H83 A109 2.1.1.86 0005886,0006730,0006814,0008168,0015948,0019386,0030269,0032259,0050897 E3GWY7 27324530 201 VKKKEPAEGWPVVSGDYIVGDPESPVAAVTLASHIEDIPIDAGAAIAGPCKTENLGIEKVIANIISNPNIRFLVLCGSEVQGHIVGQSMKALHKNGVDDKRKIIGAKGAIPYIENLPEEALERFQKQVEIVDLIDVEDADQIKEKVKECIEKDPGAFEE 5laa C 3.0 BS01 B12 C 1 G16 D17 Y18 A29 V30 I47 G49 P50 K52 T53 N55 G57 K60 V61 Q82 H84 A110 I111 G17 D18 Y19 A30 V31 I48 G50 P51 K53 T54 N56 G58 K61 V62 Q83 H85 A111 I112 2.1.1.86 0005886,0006730,0006814,0008168,0015948,0019386,0030269,0032259,0050897 E3GWY7 27324530 201 HMVKKKEPAEGWPVVSGDYIVGDPESPVAAVTLASHIEDIPIDAGAAIAGPCKTENLGIEKVIANIISNPNIRFLVLCGSEVQGHIVGQSMKALHKNGVDDKRKIIGAKGAIPYIENLPEEALERFQKQVEIVDLIDVEDADQIKEKVKECIEKDPGAFE 5nsa A 1.273 BS01 B12 A 1 S359 G360 Y362 L363 F376 W377 Q378 L379 L387 L388 Q389 G390 S56 G57 Y59 L60 F73 W74 Q75 L76 L84 L85 Q86 G87 ? P20062 28910388 501 DHMQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW 5req A 2.2 BS03 B12 A 1 L119 A139 R207 H244 E247 G333 W334 E370 A371 A373 G609 H610 D611 R612 G613 I617 S655 L657 G685 G686 V687 Y705 T706 T709 L116 A136 R204 H241 E244 G330 W331 E367 A368 A370 G606 H607 D608 R609 G610 I614 S652 L654 G682 G683 V684 Y702 T703 T706 F89 Y243 H244 K604 D608 H610 F86 Y240 H241 K601 D605 H607 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 9772164 1800 LPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQFAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 5req C 2.2 BS03 B12 C 1 L119 A139 R207 H244 E247 G333 W334 E370 A371 A373 G609 H610 D611 R612 G613 I617 S655 L657 G685 G686 V687 Y705 T706 T709 L116 A136 R204 H241 E244 G330 W331 E367 A368 A370 G606 H607 D608 R609 G610 I614 S652 L654 G682 G683 V684 Y702 T703 T706 F89 Y243 H244 K604 D608 H610 F86 Y240 H241 K601 D605 H607 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 9772164 2800 LPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQFAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 5t8y A 2.653 BS03 B12 A 1 R36 E50 R57 C97 Y105 S139 D140 R141 A142 S152 M157 I158 V167 L169 G207 L209 S216 C240 R35 E49 R56 C96 Y104 S138 D139 R140 A141 S151 M156 I157 V166 L168 G206 L208 S215 C239 1.17.99.6 0005737,0006400,0008033,0008616,0016491,0046872,0051536,0051539,0052693 P97030 27638883 503 NVYQLKEELIEYAKSIGVDKIGFTTADTFDSLKDRLILQESLGYLSGFEEPDIEKRVTPKLLLPKAKSIVAIALAYPSRMKDAPRSTRTERRGIFCRASWGKDYHDVLREKLDLLEDFLKSKHEDIRTKSMVDTGELSDRAVAERAGIGFSAKNCMITTPEYGSYVYLAEMITNIPFEPDVPIEDMCGSCTKCLDACPTGALVNPGQLNAQRCISFLTQTKGFLPDEFRTKIGNRLYGCDTCQTVCPLNKGKDFHLHPEMEPDPEIAKPLLKPLLAISNREFKEKFGHVSGSWRGKKPIQRNAILALAHFKDASALPELTELMHKDPRPVIRGTAAWAIGKIGDPAYAEELEKALEKEKDEEAKLEIEKGIELL 5t8y B 2.653 BS04 B12 B 1 S32 R36 S47 E50 R57 C97 S139 D140 R141 A142 S152 M157 I158 V167 L169 G207 L209 S216 C240 S31 R35 S46 E49 R56 C96 S135 D136 R137 A138 S148 M153 I154 V163 L165 G203 L205 S212 C236 1.17.99.6 0005737,0006400,0008033,0008616,0016491,0046872,0051536,0051539,0052693 P97030 27638883 503 NVYQLKEELIEYAKSIGVDKIGFTTADTFDSLKDRLILQESLGYLSGFEEPDIEKRVTPKLLLPKAKSIVAIALAYPSRMKDAPRSTRTERRGIFCRASWGKDYHDVLREKLDLLEDFLKSKHEDIRTKSMGELSDRAVAERAGIGFSAKNCMITTPEYGSYVYLAEMITNIPFEPDVPIEDMCGSCTKCLDACPTGALVNPGQLNAQRCISFLTQTKGFLPDEFRTKIGNRLYGCDTCQTVCPLNKGKDFHLHPEMEPDPEIAKPLLKPLLAISNREFKEKFGHVSGSWRGKKPIQRNAILALAHFKDASALPELTELMHKDPRPVIRGTAAWAIGKIGDPAYAEELEKALEKEKDEEAKLEIEKGIELLK 5ul3 A 1.8 BS02 B12 A 1 F131 R135 S139 L143 G182 L183 S184 F187 G216 N217 C237 K239 E240 G241 E242 E308 R311 P322 H325 K326 A361 E363 F126 R130 S134 L138 G177 L178 S179 F182 G211 N212 C232 K234 E235 G236 E237 E303 R306 P317 H320 K321 A356 E358 ? 0003824,0031419,0046872,0051536,0051539 O24770 28346939 802 STKSIEYYLKELKEIFSQIWLKPSEIEKRCEELFKRSKEFDYKRILVSGETDNTTLYVIEDSSKIHVFSPNRDLRENPLLMRWHPSWYEIESKEIYYKCFLSCEELYEHLELPTVTLVNLCVIENFPIPRLNLSTGTLSSYLRKEQLAKVELIDMQVGTTINQIIKNLLDSQPDIIGLSVNFGQKKLAFEILDLIYSHIENGDLSSIITVGNVIPSFSPEQFFERYPSLLICDKEGEYTLRDLIKMLKKELKLDEVNGISYVDESGEVKHNVAETVNFKEEVPTPSLDILGEISKFRGALTLETSRGCDYSRCTFCPRDHKLRSWRPLSVEQTLKQLDDILRAGKHFNIKPHIYMADEEFIGELPNGTEAQRIIDICEGLLKREEKIKFDFAARADSVYEPKRTKEWNVERLKMWHYCALAGADRIFIGVESGSNQQLKRYGKGTTSEQNIIALRLVSALGINLRIGFIMFDQLMKGLDNLKENLDFLERTDALMKPIDIGDMTYEELYDKLLNDKEFIEKHKTGKPVYTIVSYMLASMEILMNTPYSRMVQLTERKEEVNLIMNDGKPDMNMGRYATSFVDKTNGNLSEACQMWIDSNFGVMYTIKSLHKVANPREKKKLYSYMETHREISHFLLKYLVYNLSPDKESQIILSDFLRMHSMEHIKINVGDGSKENILNVMTNWQLIMEKLLRDVEADLNKGIITDSEDHRLHNTLKRWFSDMGNWS 5ul4 A 1.85 BS02 B12 A 1 F131 R135 S139 L143 G182 L183 S184 F187 G216 N217 C237 K239 E240 G241 E242 E308 R311 P322 H325 K326 A361 E363 F127 R131 S135 L139 G178 L179 S180 F183 G212 N213 C233 K235 E236 G237 E238 E304 R307 P318 H321 K322 A357 E359 ? 0003824,0031419,0046872,0051536,0051539 O24770 28346939 802 LSTKSIEYYLKELKEIFSQIWLKPSEIEKRCEELFKRSKEFDYKRILVSGETDNTTLYVIEDSSKIHVFSPNRDLRENPLLMRWHPSWYEIESKEIYYKCFLSCEELYEHLELPTVTLVNLCVIENFPIPRLNLSTGTLSSYLRKEQLAKVELIDMQVGTTINQIIKNLLDSQPDIIGLSVNFGQKKLAFEILDLIYSHIENGDLSSIITVGNVIPSFSPEQFFERYPSLLICDKEGEYTLRDLIKMLKKELKLDEVNGISYVDESGEVKHNVAETVNFKEEVPTPSLDILGEISKFRGALTLETSRGCDYSRCTFCPRDHKLRSWRPLSVEQTLKQLDDILRAGKHFNIKPHIYMADEEFIGELPNGTEAQRIIDICEGLLKREEKIKFDFAARADSVYEPKRTKEWNVERLKMWHYCALAGADRIFIGVESGSNQQLKRYGKGTTSEQNIIALRLVSALGINLRIGFIMFDQLMKGLDNLKENLDFLERTDALMKPIDIGDMTYEELYDKLLNDKEFIEKHKTGKPVYTIVSYMLASMEILMNTPYSRMVQLTERKEEVNLIMNDGKPDMNMGRYATSFVDKTNGNLSEACQMWIDSNFGVMYTIKSLHKVANPREKKKLYSYMETHREISHFLLKYLVYNLSPDKESQIILSDFLRMHSMEHILDNVGDGSKENILNVMTNWQLIMEKLLRDVEADLNKGIITDSEDHRLHNTLKRWFSDMGNWSL 5uos A 2.51 BS01 B12 A 1 L34 L35 P36 D104 P113 I115 L116 A117 Q118 T119 H122 Y129 Q131 R144 S146 C149 I160 F196 W200 L37 L38 P39 D107 P116 I118 L119 A120 Q121 T122 H125 Y132 Q134 R147 S149 C152 I163 F199 W203 1.16.1.6,2.5.1.151 Q9Y4U1 28544088 301 SNAMEPKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRLALLGL 5yrt A 1.7 BS02 B12 B 1 V173 A174 E205 Q267 M268 M373 F374 A375 V173 A174 E205 Q267 M268 M373 F374 A375 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 29797764 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 5yrt B 1.7 BS01 B12 B 1 K135 T137 L148 L153 P155 Q156 A157 Y196 S200 K93 T95 L106 L111 P113 Q114 A115 Y154 S158 4.2.1.28 Q59471 29797764 1601 GPGGFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 5yrt D 1.7 BS02 B12 E 1 V173 E205 Q267 M268 M373 F374 V173 E205 Q267 M268 M373 F374 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 29797764 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 5yrt E 1.7 BS01 B12 E 1 D112 K135 T137 L148 L153 P155 Q156 A157 P158 Y196 S200 D66 K89 T91 L102 L107 P109 Q110 A111 P112 Y150 S154 4.2.1.28 Q59471 29797764 1601 GFLTEVGEARQGQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 5yrt G 1.7 BS02 B12 H 1 T172 V173 A174 E205 Q267 M268 M373 F374 T172 V173 A174 E205 Q267 M268 M373 F374 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 29797764 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNEID 5yrt H 1.7 BS01 B12 H 1 D112 K135 T137 L148 L153 P155 Q156 A157 S200 D67 K90 T92 L103 L108 P110 Q111 A112 S155 4.2.1.28 Q59471 29797764 1601 GFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVA 5yrt J 1.7 BS02 B12 K 1 V173 A174 E205 Q267 M268 S301 M373 F374 V173 A174 E205 Q267 M268 S301 M373 F374 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 29797764 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNEID 5yrt K 1.7 BS01 B12 K 1 K135 T137 L148 L153 P155 Q156 A157 P158 S200 K93 T95 L106 L111 P113 Q114 A115 P116 S158 4.2.1.28 Q59471 29797764 1601 GPGGFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 5yrv A 1.55 BS02 B12 B 1 V173 A174 E205 Q267 M268 M373 F374 V173 A174 E205 Q267 M268 M373 F374 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 29797764 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 5yrv B 1.55 BS01 B12 B 1 D112 K135 T137 L148 L153 P155 Q156 A157 P158 S200 D70 K93 T95 L106 L111 P113 Q114 A115 P116 S158 4.2.1.28 Q59471 29797764 1601 GPGGFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 5yrv D 1.55 BS02 B12 E 1 T172 V173 E205 Q267 M268 S301 M373 F374 A375 T172 V173 E205 Q267 M268 S301 M373 F374 A375 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 29797764 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 5yrv E 1.55 BS01 B12 E 1 K135 T137 L148 L153 P155 Q156 A157 P158 S200 K89 T91 L102 L107 P109 Q110 A111 P112 S154 4.2.1.28 Q59471 29797764 1601 GFLTEVGEARQGQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 5yrv G 1.55 BS02 B12 H 1 T172 V173 A174 E205 Q267 M268 M373 F374 T172 V173 A174 E205 Q267 M268 M373 F374 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 29797764 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNEID 5yrv H 1.55 BS01 B12 H 1 D112 K135 T137 L148 L153 P155 Q156 A157 S200 D67 K90 T92 L103 L108 P110 Q111 A112 S155 4.2.1.28 Q59471 29797764 1601 GFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 5yrv J 1.55 BS02 B12 K 1 V173 A174 E205 Q267 M268 M373 F374 V173 A174 E205 Q267 M268 M373 F374 Q141 H143 E170 E221 Q296 D335 S362 Q141 H143 E170 E221 Q296 D335 S362 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 29797764 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 5yrv K 1.55 BS01 B12 K 1 K135 T137 L148 L153 P155 Q156 A157 P158 S200 K93 T95 L106 L111 P113 Q114 A115 P116 S158 4.2.1.28 Q59471 29797764 1601 GPGGFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 5ysh A 1.9 BS02 B12 B 1 A172 E205 Q267 M268 S301 M373 F374 A172 E205 Q267 M268 S301 M373 F374 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 29797764 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETAVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 5ysh B 1.9 BS01 B12 B 1 D112 K135 T137 N150 L153 P155 Q156 A157 S200 D67 K90 T92 N105 L108 P110 Q111 A112 S155 4.2.1.28 Q59471 29797764 1601 GFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRV 5ysh D 1.9 BS02 B12 E 1 A172 V173 E205 Q267 M268 S301 M373 F374 A172 V173 E205 Q267 M268 S301 M373 F374 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 29797764 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETAVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDP 5ysh E 1.9 BS01 B12 E 1 D112 K135 T137 L148 L153 P155 Q156 A157 P158 R193 S200 D65 K88 T90 L101 L106 P108 Q109 A110 P111 R146 S153 4.2.1.28 Q59471 29797764 1601 FLTEVGEARQTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVA 5ysh G 1.9 BS02 B12 H 1 E205 D234 Q267 M268 S301 F374 E205 D234 Q267 M268 S301 F374 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 29797764 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETAVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDP 5ysh H 1.9 BS01 B12 H 1 K135 T137 L153 P155 Q156 A157 S200 K92 T94 L110 P112 Q113 A114 S157 4.2.1.28 Q59471 29797764 1601 PGGFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVA 5ysh J 1.9 BS02 B12 K 1 E205 D234 Q267 M268 S301 M373 F374 E205 D234 Q267 M268 S301 M373 F374 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 29797764 1601 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETAVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 5ysh K 1.9 BS01 B12 K 1 K135 T137 L148 L153 P155 Q156 A157 S200 K84 T86 L93 L98 P100 Q101 A102 S145 4.2.1.28 Q59471 29797764 1601 TEVGEARQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRV 5ysn A 2.001 BS01 B12 B 1 P194 A226 Q246 S247 F258 S295 F329 I330 M401 L402 P194 A226 Q246 S247 F258 S295 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 29797764 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 5ysn B 2.001 BS01 B12 B 1 R206 V207 E228 R229 Y241 E253 R256 C258 S260 R163 V164 E185 R186 Y198 E210 R213 C215 S217 4.3.1.7 0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P19636 29797764 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 5ysn C 2.001 BS01 B12 D 1 P194 A226 Q246 S247 F258 F329 I330 M401 L402 P194 A226 Q246 S247 F258 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 29797764 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 5ysn D 2.001 BS01 B12 D 1 L169 R206 V207 E228 R229 Y241 E253 R256 C258 S260 L126 R163 V164 E185 R186 Y198 E210 R213 C215 S217 4.3.1.7 0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P19636 29797764 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 5ysr A 2.05 BS01 B12 B 1 N193 T196 A226 H227 Q246 E257 F258 F329 I330 L402 N193 T196 A226 H227 Q246 E257 F258 F329 I330 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 29797764 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 5ysr B 2.05 BS01 B12 B 1 L169 R206 V207 K208 E228 R229 Y241 E253 R256 C258 S260 N261 L126 R163 V164 K165 E185 R186 Y198 E210 R213 C215 S217 N218 4.3.1.7 0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P19636 29797764 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 5ysr C 2.05 BS01 B12 D 1 V195 T196 A226 H227 Q246 S247 F258 F329 I330 M401 L402 V195 T196 A226 H227 Q246 S247 F258 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 29797764 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 5ysr D 2.05 BS01 B12 D 1 L169 V207 G227 E228 R229 Y241 E253 R256 C258 S260 L126 V164 G184 E185 R186 Y198 E210 R213 C215 S217 4.3.1.7 0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P19636 29797764 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMT 6d5k A 2.85 BS01 B12 A 1 T168 A169 F170 I171 R186 R190 D218 F221 M239 T80 A81 F82 I83 R98 R102 D130 F133 M151 2.5.1.- Q96EY8 30282455 302 DDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMK 6d5k A 2.85 BS02 B12 A 2 V86 D90 Q122 S126 V8 D12 Q44 S48 2.5.1.- Q96EY8 30282455 303 DDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMK 6d5k B 2.85 BS01 B12 A 2 L167 T168 F170 I171 R186 R190 S217 F221 L111 T112 F114 I115 R130 R134 S161 F165 2.5.1.- Q96EY8 30282455 303 KIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIY 6d5k C 2.85 BS01 B12 A 1 F71 V86 D90 Q122 S126 F8 V23 D27 Q59 S63 2.5.1.- Q96EY8 30282455 302 DKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMKN 6d5x A 2.4 BS01 B12 A 1 T168 A169 F170 I171 R186 R190 S217 F221 T80 A81 F82 I83 R98 R102 S129 F133 2.5.1.- Q96EY8 30282455 302 DDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYM 6d5x A 2.4 BS03 B12 B 1 V86 D90 Q122 S126 V8 D12 Q44 S48 2.5.1.- Q96EY8 30282455 302 DDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYM 6d5x B 2.4 BS01 B12 B 1 L167 T168 F170 I171 R186 R190 F221 L111 T112 F114 I115 R130 R134 F165 2.5.1.- Q96EY8 30282455 302 KIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYM 6d5x C 2.4 BS01 B12 A 1 F71 V86 D90 Q122 G125 S126 Y142 F11 V26 D30 Q62 G65 S66 Y82 2.5.1.- Q96EY8 30282455 302 KTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMKN 6ffv A BS01 B12 A 1 R25 H27 D67 A70 V76 F79 C80 A84 Y85 T131 T132 F135 R153 Y157 R25 H27 D67 A70 V76 F79 C80 A84 Y85 T131 T132 F135 R153 Y157 301 MGLNLTRRQQIAIGFVLVLMMLLTRSHHWASIHSLPDASWAIFFLLGVYVRALWVVPALIAASVVIDYVAITWGGVSDFCVSPAYWLLIPAYLALFAGGRFYARGHSLSLLGLFRLAGVALAVVAVAQLLTTGGFYFYSGRFADPTLAGLVLRLEKYFPPMLGTFALYVGLAATVHVALAAVFRRRHHHHHHHH 6h9e A 1.82 BS01 B12 A 1 S13 C15 H16 A17 V18 G19 I22 L23 S61 L63 Y64 G65 G91 G92 N93 V95 V96 Y117 T121 P123 S13 C15 H16 A17 V18 G19 I22 L23 S61 L63 Y64 G65 G91 G92 N93 V95 V96 Y117 T121 P123 D14 H16 D14 H16 5.4.99.1 0005515,0016853,0016866,0019553,0019670,0031419,0046872,0050097 P80078 35793207 201 MEKKTIVLGVIGSDCHAVGNKILDHAFTNAGFNVVNIGVLSPQENFIKAAIETKADAILVSSLYGQGEIDCKGLRQKCDEAGLEGILLYVGGNIVVGKQHWPDVEKRFKDMGYDRVYAPGTPPEVGIADLKKDLNIE 6h9e B 1.82 BS01 B12 A 1 A97 R100 N123 Y181 T220 M294 G295 G296 F297 E330 G333 I334 F471 A97 R100 N123 Y181 T220 M294 G295 G296 F297 E330 G333 I334 F471 R100 E171 R100 E171 5.4.99.1 0003824,0005515,0016853,0016866,0019553,0019670,0031419,0050097 P80077 35793207 201 MELKNKKWTDEEFHKQREEVLQQWPTGKEVDLQEAVDYLKKIPAEKNFAEKLVLAKKKGITMAQPRAGVALLDEHIELLRYLQDEGGADFLPSTIDAYTRQNRYDECENGIKESEKAGRSLLNGFPGVNHGVKGCRKVLEAVNLPLQARHGTPDSRLLAEIIHAGGWTSNEGGGISYNVPYAKNVTIEKSLLDWQYCDRLVGFYEEQGVHINREPFGPLTGTLVPPSMSNAVGITEALLAAEQGVKNITVGYGECGNMIQDIAALRCLEEQTNEYLKAYGYNDVFVTTVFHQWMGGFPQDESKAFGVIVTATTIAALAGATKVIVKTPHEAIGIPTKEANAAGIKATKMALNMLEGQRMPMSKELETEMAVIKAETKCILDKMFELGKGDLAIGTVKAFETGVMDIPFGPSKYNAGKMMPVRDNLGCVRYLEFGNVPFTEEIKNYNRERLQERAKFEGRDVSFQMVIDDIFAVGKGRLIGRPE 6h9e C 1.82 BS01 B12 C 1 S13 C15 H16 A17 V18 G19 I22 L23 S61 L63 Y64 G65 G91 G92 N93 V95 V96 Y117 T121 P123 S13 C15 H16 A17 V18 G19 I22 L23 S61 L63 Y64 G65 G91 G92 N93 V95 V96 Y117 T121 P123 D14 H16 D14 H16 5.4.99.1 0005515,0016853,0016866,0019553,0019670,0031419,0046872,0050097 P80078 35793207 201 MEKKTIVLGVIGSDCHAVGNKILDHAFTNAGFNVVNIGVLSPQENFIKAAIETKADAILVSSLYGQGEIDCKGLRQKCDEAGLEGILLYVGGNIVVGKQHWPDVEKRFKDMGYDRVYAPGTPPEVGIADLKKDLNIE 6h9e D 1.82 BS01 B12 C 1 A97 R100 N123 Y181 T220 M294 G295 G296 F297 E330 A331 G333 I334 F471 A97 R100 N123 Y181 T220 M294 G295 G296 F297 E330 A331 G333 I334 F471 R100 E171 R100 E171 5.4.99.1 0003824,0005515,0016853,0016866,0019553,0019670,0031419,0050097 P80077 35793207 201 MELKNKKWTDEEFHKQREEVLQQWPTGKEVDLQEAVDYLKKIPAEKNFAEKLVLAKKKGITMAQPRAGVALLDEHIELLRYLQDEGGADFLPSTIDAYTRQNRYDECENGIKESEKAGRSLLNGFPGVNHGVKGCRKVLEAVNLPLQARHGTPDSRLLAEIIHAGGWTSNEGGGISYNVPYAKNVTIEKSLLDWQYCDRLVGFYEEQGVHINREPFGPLTGTLVPPSMSNAVGITEALLAAEQGVKNITVGYGECGNMIQDIAALRCLEEQTNEYLKAYGYNDVFVTTVFHQWMGGFPQDESKAFGVIVTATTIAALAGATKVIVKTPHEAIGIPTKEANAAGIKATKMALNMLEGQRMPMSKELETEMAVIKAETKCILDKMFELGKGDLAIGTVKAFETGVMDIPFGPSKYNAGKMMPVRDNLGCVRYLEFGNVPFTEEIKNYNRERLQERAKFEGRDVSFQMVIDDIFAVGKGRLIGRPE 6h9f A 2.1 BS01 B12 A 1 S13 C15 H16 A17 V18 G19 I22 L23 S61 L63 Y64 G65 G91 G92 N93 V95 V96 Y117 T121 P123 S13 C15 H16 A17 V18 G19 I22 L23 S61 L63 Y64 G65 G91 G92 N93 V95 V96 Y117 T121 P123 D14 H16 D14 H16 5.4.99.1 0005515,0016853,0016866,0019553,0019670,0031419,0046872,0050097 P80078 35793207 201 MEKKTIVLGVIGSDCHAVGNKILDHAFTNAGFNVVNIGVLSPQENFIKAAIETKADAILVSSLYGQGEIDCKGLRQKCDEAGLEGILLYVGGNIVVGKQHWPDVEKRFKDMGYDRVYAPGTPPEVGIADLKKDLNIE 6h9f B 2.1 BS01 B12 A 1 A97 R100 N123 Y181 T220 M294 G295 G296 F297 E330 G333 I334 P410 F471 A97 R100 N123 Y181 T220 M294 G295 G296 F297 E330 G333 I334 P410 F471 R100 E171 R100 E171 5.4.99.1 0003824,0005515,0016853,0016866,0019553,0019670,0031419,0050097 P80077 35793207 201 MELKNKKWTDEEFHKQREEVLQQWPTGKEVDLQEAVDYLKKIPAEKNFAEKLVLAKKKGITMAQPRAGVALLDEHIELLRYLQDEGGADFLPSTIDAYTRQNRYDECENGIKESEKAGRSLLNGFPGVNHGVKGCRKVLEAVNLPLQARHGTPDSRLLAEIIHAGGWTSNEGGGISYNVPYAKNVTIEKSLLDWQYCDRLVGFYEEQGVHINREPFGPLTGTLVPPSMSNAVGITEALLAAEQGVKNITVGYGECGNMIQDIAALRCLEEQTNEYLKAYGYNDVFVTTVFHQWMGGFPQDESKAFGVIVTATTIAALAGATKVIVKTPHEAIGIPTKEANAAGIKATKMALNMLEGQRMPMSKELETEMAVIKAETKCILDKMFELGKGDLAIGTVKAFETGVMDIPFGPSKYNAGKMMPVRDNLGCVRYLEFGNVPFTEEIKNYNRERLQERAKFEGRDVSFQMVIDDIFAVGKGRLIGRPE 6h9f C 2.1 BS01 B12 C 1 S13 C15 H16 A17 V18 G19 I22 L23 S61 L63 Y64 G65 G91 G92 N93 V95 V96 Y117 T121 P123 S13 C15 H16 A17 V18 G19 I22 L23 S61 L63 Y64 G65 G91 G92 N93 V95 V96 Y117 T121 P123 D14 H16 D14 H16 5.4.99.1 0005515,0016853,0016866,0019553,0019670,0031419,0046872,0050097 P80078 35793207 201 MEKKTIVLGVIGSDCHAVGNKILDHAFTNAGFNVVNIGVLSPQENFIKAAIETKADAILVSSLYGQGEIDCKGLRQKCDEAGLEGILLYVGGNIVVGKQHWPDVEKRFKDMGYDRVYAPGTPPEVGIADLKKDLNIE 6h9f D 2.1 BS01 B12 C 1 A97 R100 N123 Y181 T220 M294 G295 G296 F297 E330 A331 G333 I334 F471 A97 R100 N123 Y181 T220 M294 G295 G296 F297 E330 A331 G333 I334 F471 R100 E171 R100 E171 5.4.99.1 0003824,0005515,0016853,0016866,0019553,0019670,0031419,0050097 P80077 35793207 201 MELKNKKWTDEEFHKQREEVLQQWPTGKEVDLQEAVDYLKKIPAEKNFAEKLVLAKKKGITMAQPRAGVALLDEHIELLRYLQDEGGADFLPSTIDAYTRQNRYDECENGIKESEKAGRSLLNGFPGVNHGVKGCRKVLEAVNLPLQARHGTPDSRLLAEIIHAGGWTSNEGGGISYNVPYAKNVTIEKSLLDWQYCDRLVGFYEEQGVHINREPFGPLTGTLVPPSMSNAVGITEALLAAEQGVKNITVGYGECGNMIQDIAALRCLEEQTNEYLKAYGYNDVFVTTVFHQWMGGFPQDESKAFGVIVTATTIAALAGATKVIVKTPHEAIGIPTKEANAAGIKATKMALNMLEGQRMPMSKELETEMAVIKAETKCILDKMFELGKGDLAIGTVKAFETGVMDIPFGPSKYNAGKMMPVRDNLGCVRYLEFGNVPFTEEIKNYNRERLQERAKFEGRDVSFQMVIDDIFAVGKGRLIGRPE 6oxc A 1.9 BS01 B12 A 1 L135 A155 R223 E263 W350 E386 A387 L388 A389 G628 H629 D630 R631 G632 I636 S674 L676 G704 G705 F724 P725 T728 L130 A150 R218 E258 W345 E381 A382 L383 A384 G611 H612 D613 R614 G615 I619 S657 L659 G687 G688 F707 P708 T711 Y105 Y259 H260 K623 D627 H629 Y100 Y254 H255 K606 D610 H612 5.4.99.2 0003824,0004494,0005737,0005886,0016853,0016866,0019678,0031419,0046872 P9WJK5 31672889 1000 PVIGSFAGVPLHSERAAQSPTEAAVHTHVAAAAAAHGYTPEQLVWHTPEGIDVTPVYIAADRAAAEAEGYPLHSFPGEPPFVRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLATHRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGAVLPILALYVVAAEEQGVAPEQLAGTIQNDILKEFMVRNTYIYPPKPSMRIISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIRAGLNAGLDIDSFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFAPKSAKSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDEALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHRLARRARAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVVGVNKYQVPSRVRAEQLAKLQRLRAGRDEPAVRAALAELTRAAAEQGRAGADGLGNNLLALAIDAARAQATVGEISEALEKVYGRHRAEIRTISGVYRDEVGKAPNIAAATELVEKFAEADGRRPRILIAKMGQDGHDRGQKVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTLVPALRDALAQVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADAAIDLLHRLAERLGYTL 6oxd A 2.0 BS01 B12 A 1 Y105 L135 H138 A155 R223 E263 G349 W350 E386 A387 A389 L390 G628 H629 D630 R631 S674 L676 A678 G704 G705 F724 P725 T728 Y100 L130 H133 A150 R218 E258 G344 W345 E381 A382 A384 L385 G615 H616 D617 R618 S661 L663 A665 G691 G692 F711 P712 T715 Y105 Y259 H260 K623 D627 H629 Y100 Y254 H255 K610 D614 H616 5.4.99.2 0003824,0004494,0005737,0005886,0016853,0016866,0019678,0031419,0046872 P9WJK5 31672889 1000 PVIGSFAGVPLHSERAAQSPTEAAVHTHVAAAAAAHGYTPEQLVWHTPEGIDVTPVYIAADRAAAEAEGYPLHSFPGEPPFVRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLATHRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGAVLPILALYVVAAEEQGVAPEQLAGTIQNDILKEFMVRNTYIYPPKPSMRIISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIRAGLNAGLDIDSFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFAPKSAKSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDEALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHRLARRARAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVVGVNKYQVPEDHEIEVLKVENSRVRAEQLAKLQRLRAGRDEPAVRAALAELTRAAAELGNNLLALAIDAARAQATVGEISEALEKVYGRHRAEIRTISGVYRDEVGKAPNIAAATELVEKFAEADGRRPRILIAKMGQDGHDRGQKVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTLVPALRDALAQVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADAAIDLLHRLAERLGYTL 6req A 2.2 BS02 B12 A 1 Y89 F117 L119 H122 A139 R207 E247 G333 W334 E370 A371 A373 G609 H610 D611 R612 G613 I617 Y621 S655 L657 G659 G685 G686 Y705 T706 T709 Y88 F116 L118 H121 A138 R206 E246 G332 W333 E369 A370 A372 G608 H609 D610 R611 G612 I616 Y620 S654 L656 G658 G684 G685 Y704 T705 T708 Y89 Y243 H244 K604 D608 H610 Y88 Y242 H243 K603 D607 H609 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 10387043 1800 STLPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 6req C 2.2 BS02 B12 C 1 Y89 F117 L119 H122 A139 V206 R207 H244 E247 G333 W334 E370 A371 A373 L374 G609 H610 D611 R612 G613 I617 Y621 S655 L657 G685 G686 V687 Y705 T706 T709 Y88 F116 L118 H121 A138 V205 R206 H243 E246 G332 W333 E369 A370 A372 L373 G608 H609 D610 R611 G612 I616 Y620 S654 L656 G684 G685 V686 Y704 T705 T708 Y89 Y243 H244 K604 D608 H610 Y88 Y242 H243 K603 D607 H609 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 10387043 2800 STLPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 6wgs A 1.5 BS01 B12 A 1 L114 K115 S116 F117 V118 R133 R137 S166 F170 W184 L103 K104 S105 F106 V107 R122 R126 S155 F159 W173 2.5.1.17 0005524,0005737,0006779,0008817,0009236,0016740 P9WP99 33199623 201 RGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDGDVLWRPGG 6wgv A 2.151 BS01 B12 A 1 L114 K115 S116 F117 V118 R133 R137 S166 D167 F170 W184 L100 K101 S102 F103 V104 R119 R123 S152 D153 F156 W170 2.5.1.17 0005524,0005737,0006779,0008817,0009236,0016740 P9WP99 33199623 201 DGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDGDVLWRPG 6wh5 A 1.866 BS02 B12 A 1 V3 H4 L5 T6 I8 M23 Y36 F71 G74 A75 P88 P89 L90 V1 H2 L3 T4 I6 M21 Y34 F69 G72 A73 P86 P87 L88 2.5.1.17 0005524,0005737,0006779,0008817,0009236,0016740 P9WP99 33199623 204 VHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDGDVLWRPGG 6wh5 A 1.866 BS04 B12 C 2 F117 V118 R133 R137 S166 D167 F170 F115 V116 R131 R135 S164 D165 F168 2.5.1.17 0005524,0005737,0006779,0008817,0009236,0016740 P9WP99 33199623 205 VHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDGDVLWRPGG 6wh5 B 1.866 BS02 B12 A 1 F117 V118 R133 R137 S166 D167 F170 F115 V116 R131 R135 S164 D165 F168 2.5.1.17 0005524,0005737,0006779,0008817,0009236,0016740 P9WP99 33199623 204 VHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDGDVLWRPGG 6wh5 B 1.866 BS04 B12 C 1 H4 L5 T6 I8 Y36 F71 G74 A75 S78 P88 P89 L90 H2 L3 T4 I6 Y34 F69 G72 A73 S76 P86 P87 L88 2.5.1.17 0005524,0005737,0006779,0008817,0009236,0016740 P9WP99 33199623 204 VHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDGDVLWRPGG 6wh5 C 1.866 BS03 B12 C 1 F117 V118 R133 R137 S166 D167 F170 F115 V116 R131 R135 S164 D165 F168 2.5.1.17 0005524,0005737,0006779,0008817,0009236,0016740 P9WP99 33199623 204 VHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDGDVLWRPGG 6wh5 C 1.866 BS04 B12 C 2 V3 H4 L5 T6 I8 M23 Y36 D40 F71 G74 A75 P88 P89 L90 V1 H2 L3 T4 I6 M21 Y34 D38 F69 G72 A73 P86 P87 L88 2.5.1.17 0005524,0005737,0006779,0008817,0009236,0016740 P9WP99 33199623 205 VHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDGDVLWRPGG 6wte A 1.67 BS02 B12 A 1 N11 V13 I17 A21 L25 T67 R69 N70 T71 V74 G104 G105 I106 V125 G127 P128 G129 E130 L218 E236 K240 T270 F414 N11 V13 I17 A21 L25 T67 R69 N70 T71 V74 G104 G105 I106 V125 G127 P128 G129 E130 L218 E236 K240 T270 F414 ? 0003824,0005829,0031419,0046872,0051536,0051539 E4N8S5 33462497 802 MSRLVLLVNPNKVHPPIAPYALDVLTTALEDEGFEVEVLDLTFRRDDWKTCLHEYFAERSPMLVGVTVRNTDTVYAFEQRPFVGEHREIITEIRRLTDAPVVGGGIGFSTMPFALVEYFGIEYGVKGPGEKILCELATAISEGRDTAGIPGLIRNTERGAVRVPPAVLTVRHGKTQPAEPTGQFEPRVWQVDQLSVYRRRSGVPRKVDNLEYYRRGGLGSILTKNGCAYRCSHCVEPDAKGTRYGQRELASVVDEMESLAAQGILDQHTTDSEFNLSIAHAKNLLREIVRRRHADPDNPLNRLRLWVYCQPSPFDEEFADLLAAAGCRGVNVGSDHIRPELLSGWKVTEKGGTYYTFEDTERLVRLCRERGILTMVEALFGMPGETPETVRACVDAFMALDATVTGFSLGLRLFPYTPMGIEIAEQCAGVRTAPGLQSNTADGPIVLKPLRMCASPAEYERQFMFDEHGNFRLVCYFSPGLLPDPARAADPEERWHGAVADLWALIDPADHHRVMLPTVEGMSEHDNNYADNPFLTSLGGLGYTGAFWSHWRGREEIMRKAREAAAQ 6wte B 1.67 BS02 B12 B 1 N11 V13 I17 A21 L25 T67 R69 N70 T71 V74 Y75 G104 G105 I106 V125 G127 P128 G129 E130 L218 E236 K240 T270 F414 N11 V13 I17 A21 L25 T67 R69 N70 T71 V74 Y75 G104 G105 I106 V125 G127 P128 G129 E130 L207 E225 K229 T259 F403 ? 0003824,0005829,0031419,0046872,0051536,0051539 E4N8S5 33462497 802 MSRLVLLVNPNKVHPPIAPYALDVLTTALEDEGFEVEVLDLTFRRDDWKTCLHEYFAERSPMLVGVTVRNTDTVYAFEQRPFVGEHREIITEIRRLTDAPVVGGGIGFSTMPFALVEYFGIEYGVKGPGEKILCELATAISEGRDTAGIPGLIRNTERGAVRVPPPAEPTGQFEPRVWQVDQLSVYRRRSGVPRKVDNLEYYRRGGLGSILTKNGCAYRCSHCVEPDAKGTRYGQRELASVVDEMESLAAQGILDQHTTDSEFNLSIAHAKNLLREIVRRRHADPDNPLNRLRLWVYCQPSPFDEEFADLLAAAGCRGVNVGSDHIRPELLSGWKVTEKGGTYYTFEDTERLVRLCRERGILTMVEALFGMPGETPETVRACVDAFMALDATVTGFSLGLRLFPYTPMGIEIAEQCAGVRTAPGLQSNTADGPIVLKPLRMCASPAEYERQFMFDEHGNFRLVCYFSPGLLWHGAVADLWALIDPADHHRVMLPTVNPFLTSLGGLGYTGAFWSHWRGREEIMRKAREAA 6wtf A 2.19 BS02 B12 A 1 N11 V13 I17 Y20 A21 V24 L25 T67 R69 N70 T71 T73 V74 G104 G105 I106 G107 G127 P128 G129 E130 L218 S220 E236 K240 T270 F414 N528 Y529 N10 V12 I16 Y19 A20 V23 L24 T66 R68 N69 T70 T72 V73 G103 G104 I105 G106 G126 P127 G128 E129 L205 S207 E223 K227 T257 F401 N504 Y505 ? 0003824,0005829,0031419,0046872,0051536,0051539 E4N8S5 33462497 802 SRLVLLVNPNKVHPPIAPYALDVLTTALEDEGFEVEVLDLTFRRDDWKTCLHEYFAERSPMLVGVTVRNTDTVYAFEQRPFVGEHREIITEIRRLTDAPVVGGGIGFSTMPFALVEYFGIEYGVKGPGEKILCELATAISEGRDTAGIPGLIRNTERGAVRVPPAEPTGQFEPRVWQVDQLSVYRRRSGVPRKVDNLEYYRRGGLGSILTKNGCAYRCSHCVEPDAKGTRYGQRELASVVDEMESLAAQGILDQHTTDSEFNLSIAHAKNLLREIVRRRHADPDNPLNRLRLWVYCQPSPFDEEFADLLAAAGCRGVNVGSDHIRPELLSGWKVTEKGGTYYTFEDTERLVRLCRERGILTMVEALFGMPGETPETVRACVDAFMALDATVTGFSLGLRLFPYTPMGIEIAEQCAGVRTAPGLQSNTADGPIVLKPLRMCASPAEYERQFMFDEHGNFRLVCYFSPGLLPWHGAVADLWALIDPADHHRVMLPTVEGMSEHDNNYADNPFLTSLGGLGYTGAFWSHWRGREEIMRKAREAAA 6wtf B 2.19 BS02 B12 B 1 V13 I17 A21 L25 V66 T67 R69 N70 T71 T73 V74 G104 G105 I106 G107 V125 G127 P128 G129 E130 L218 E236 K240 T270 Y308 F414 N528 Y529 V12 I16 A20 L24 V65 T66 R68 N69 T70 T72 V73 G103 G104 I105 G106 V124 G126 P127 G128 E129 L203 E221 K225 T255 Y293 F399 N504 Y505 ? 0003824,0005829,0031419,0046872,0051536,0051539 E4N8S5 33462497 802 SRLVLLVNPNKVHPPIAPYALDVLTTALEDEGFEVEVLDLTFRRDDWKTCLHEYFAERSPMLVGVTVRNTDTVYAFEQRPFVGEHREIITEIRRLTDAPVVGGGIGFSTMPFALVEYFGIEYGVKGPGEKILCELATAISEGRDTAGIPGLIRNTERGAVRVPPPTGQFEPRVWQVDQLSVYRRRSGVPRKVDNLEYYRRGGLGSILTKNGCAYRCSHCVEPDAKGTRYGQRELASVVDEMESLAAQGILDQHTTDSEFNLSIAHAKNLLREIVRRRHADPDNPLNRLRLWVYCQPSPFDEEFADLLAAAGCRGVNVGSDHIRPELLSGWKVTEKGGTYYTFEDTERLVRLCRERGILTMVEALFGMPGETPETVRACVDAFMALDATVTGFSLGLRLFPYTPMGIEIAEQCAGVRTAPGLQSNTADGPIVLKPLRMCASPAEYERQFMFDEHGNFRLVCYFSPGLLPERWHGAVADLWALIDPADHHRVMLPTVEGMSEHDNNYADNPFLTSLGGLGYTGAFWSHWRGREEIMRKARE 6x8z A 2.5 BS01 B12 A 1 W189 C261 W54 C123 1.-.-.- 0009235 Q9H3L0 32871076 301 EINSAETYFESARVECAIQTCPELLRKDFESLFPEGKLMILTVTQKTKNDMTVWSEEVEIEREVLLEKFINGAKEICYALRAEGYWADFIDPSSGLAFFGPYTNNTLDERYRHLGFSVDDLGCSKVIRHSLWGTHVVVGSIFTNATPDSHIMKKLSGN 6x8z B 2.5 BS01 B12 B 1 W189 L259 C261 W50 L114 C116 1.-.-.- 0009235 Q9H3L0 32871076 301 NSAETYFESARVECAIQTCPELLRKDFESLFPKLMILTVTQKTKNDMTVWSEEVEIEREVLLEKFINGAKEICYALRAEGYWADFIDPSSGLAFFGPYTTDERYRHLGFSVDDLGCSKVIRHSLWGTHVVVGSIFTNATPDSHIMKKLSG 6zxu A 1.73 BS03 B12 A 1 D289 F290 F291 Y379 Y426 I458 H459 N460 I463 I474 D476 T477 L478 K488 S489 F535 Y538 K542 C548 T549 R552 C561 M565 D293 F294 F295 Y383 Y430 I462 H463 N464 I467 I478 D480 T481 L482 K492 S493 F539 Y542 K546 C552 T553 R556 C565 M569 ? 0046872,0051539 K2MB66 32887524 703 AQISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSA 6zxu B 1.73 BS03 B12 B 1 D289 F290 F291 Y379 S422 Y426 I458 H459 N460 P461 I474 D476 T477 L478 K488 S489 F535 Y538 K542 C548 T549 R552 C561 M565 D292 F293 F294 Y382 S425 Y429 I461 H462 N463 P464 I477 D479 T480 L481 K491 S492 F538 Y541 K545 C551 T552 R555 C564 M568 ? 0046872,0051539 K2MB66 32887524 703 QISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSA 6zxu C 1.73 BS03 B12 C 1 D289 F290 F291 Y379 Y426 I458 H459 N460 I463 I474 D476 T477 L478 K488 S489 F535 Y538 K542 C548 T549 R552 D286 F287 F288 Y376 Y423 I455 H456 N457 I460 I471 D473 T474 L475 K485 S486 F532 Y535 K539 C545 T546 R549 ? 0046872,0051539 K2MB66 32887524 703 QISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKS 6zxx A 1.99 BS03 B12 A 1 D289 F290 F291 Y379 Y426 I458 H459 N460 P461 I463 I474 D476 T477 L478 S487 K488 S489 F535 Y538 K542 C548 T549 R552 M565 D292 F293 F294 Y382 Y429 I461 H462 N463 P464 I466 I477 D479 T480 L481 S490 K491 S492 F538 Y541 K545 C551 T552 R555 M568 ? 0046872,0051539 K2MB66 32887524 703 QISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSA 6zxx B 1.99 BS03 B12 B 1 D289 F290 F291 Y379 Y426 I458 H459 N460 P461 I463 I474 D476 T477 L478 K488 S489 F535 Y538 K542 C548 T549 R552 C561 M565 D293 F294 F295 Y383 Y430 I462 H463 N464 P465 I467 I478 D480 T481 L482 K492 S493 F539 Y542 K546 C552 T553 R556 C565 M569 ? 0046872,0051539 K2MB66 32887524 703 AQISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSA 6zxx C 1.99 BS03 B12 C 1 D293 F294 F295 Y383 Y430 I462 H463 N464 P465 I467 L468 I478 D480 T481 L482 K492 S493 F539 Y542 K546 C552 T553 R556 C565 M569 D290 F291 F292 Y380 Y427 I459 H460 N461 P462 I464 L465 I475 D477 T478 L479 K489 S490 F536 Y539 K543 C549 T550 R553 C562 M566 ? 0046872,0051539 K2MB66 32887524 803 QISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKS 6zy0 A 2.13 BS03 B12 A 1 D289 F290 F291 Y379 Y426 I458 H459 N460 P461 I463 I474 D476 T477 L478 Q488 S489 F535 Y538 K542 V545 T549 R552 M565 D293 F294 F295 Y383 Y430 I462 H463 N464 P465 I467 I478 D480 T481 L482 Q492 S493 F539 Y542 K546 V549 T553 R556 M569 ? 0046872,0051539 K2MB66 32887524 703 AQISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSQSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSA 6zy0 B 2.13 BS03 B12 B 1 D289 F290 F291 Y379 S422 Y426 I458 H459 N460 P461 I474 D476 T477 L478 Q488 S489 F535 Y538 K542 C548 T549 R552 D291 F292 F293 Y381 S424 Y428 I460 H461 N462 P463 I476 D478 T479 L480 Q490 S491 F537 Y540 K544 C550 T551 R554 ? 0046872,0051539 K2MB66 32887524 703 ISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSQSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSA 6zy0 C 2.13 BS03 B12 C 1 D289 F290 F291 Y379 Y426 I458 H459 N460 P461 I463 I474 D476 T477 L478 S487 Q488 S489 F535 Y538 K542 T549 R552 D290 F291 F292 Y380 Y427 I459 H460 N461 P462 I464 I475 D477 T478 L479 S488 Q489 S490 F536 Y539 K543 T550 R553 ? 0046872,0051539 K2MB66 32887524 703 AQISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSQSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKS 6zy1 A 1.99 BS03 B12 A 1 D289 F290 F291 Y379 Y426 I458 H459 N460 I463 I474 D476 T477 L478 K488 S489 F535 Y538 K542 V545 T549 R552 C561 M565 D292 F293 F294 Y382 Y429 I461 H462 N463 I466 I477 D479 T480 L481 K491 S492 F538 Y541 K545 V548 T552 R555 C564 M568 ? 0046872,0051539 K2MB66 32887524 703 QISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSA 6zy1 B 1.99 BS03 B12 B 1 D289 F290 F291 Y379 Y426 I458 H459 N460 P461 I474 D476 T477 L478 K488 S489 F535 Y538 K542 V545 T549 R552 C561 M565 D292 F293 F294 Y382 Y429 I461 H462 N463 P464 I477 D479 T480 L481 K491 S492 F538 Y541 K545 V548 T552 R555 C564 M568 ? 0046872,0051539 K2MB66 32887524 703 QISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSA 6zy1 C 1.99 BS03 B12 C 1 D289 F290 F291 Y379 Y426 I458 H459 N460 P461 I463 L464 I474 D476 T477 L478 K488 S489 F535 Y538 K542 V545 C548 T549 R552 M565 D288 F289 F290 Y378 Y425 I457 H458 N459 P460 I462 L463 I473 D475 T476 L477 K487 S488 F534 Y537 K541 V544 C547 T548 R551 M564 ? 0046872,0051539 K2MB66 32887524 703 QISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSS 7kdx A 1.791 BS02 B12 A 1 N18 F22 V26 L30 L71 S72 Y74 V75 W76 G100 G101 P102 G124 E125 G126 E127 L199 E201 D214 W215 G216 F247 C249 L386 N10 F14 V18 L22 L63 S64 Y66 V67 W68 G92 G93 P94 G116 E117 G118 E119 L188 E190 D203 W204 G205 F236 C238 L375 ? 0003824,0005829,0008168,0031419,0032259,0046872,0051536,0051539 A0A6B9HEI0 35110734 703 GRKVYFVGLNEYPFLPLVAGLLRTYAEQDERIAAAYDFQEPVFLVAPVQEMADGIVEPDVLALSCYVWNFRRQMKVAKLVKERYPNVLVVAGGPHVPDRPGNFFEKHPYVDVLAHGEGEVAFRELLATRLSDYTAVPGVSVRRGTEAVVGPKAKRLPRLIDTPSPYLLGVMDGAVATCRERGLRFYALWETNRGCPYSCSFCDWGSATMSTLRKFEDERLQDEIEWFARHDVEDLFICDANFGIMPRDLEIAHALAEARGELGAPRQVRVNFAKNSNDRVFDISKTWHDADLLMGTTLSMQSTDMDVLEAIDRKNIGLDNYRKLQQRYAAENIHTYTELILGLPMETARSFRDGIGSLLEAGNHEDLRVYELGILPNAPLNTPEKIEQYGLRTVPKRMYVETPDDEAETFEMVMETNAMPRDAWVESFSFIQAVQFLHNGCYTRYLSIFLRQEHGIGYTRFYEGLQDYFTGRPDTVLGALYLRMRSLYHDYIDMPALPLANLVASQPDMAADLAPYGRRRGWTIDNWGWLRIATDFDRFHTELREYLATLGLDPAGDARLEDVLRFQQDVMLRPDYSPELGKSAEYAHDWPGYFAGGLLRPRRVRVAYGDQSFGANGRYRPVPGDLKAFTMAAIGTSYPVSRMGHFCHRFESAEVTSL 7kdx B 1.791 BS01 B12 B 1 N18 F22 V26 L30 S72 Y74 V75 W76 G100 G101 P102 G124 E125 G126 E127 L199 D214 W215 G216 F247 C249 L386 Y652 N12 F16 V20 L24 S66 Y68 V69 W70 G94 G95 P96 G118 E119 G120 E121 L193 D208 W209 G210 F241 C243 L380 Y644 ? 0003824,0005829,0008168,0031419,0032259,0046872,0051536,0051539 A0A6B9HEI0 35110734 1902 SRGRKVYFVGLNEYPFLPLVAGLLRTYAEQDERIAAAYDFQEPVFLVAPVQEMADGIVEPDVLALSCYVWNFRRQMKVAKLVKERYPNVLVVAGGPHVPDRPGNFFEKHPYVDVLAHGEGEVAFRELLATRLSDHPDYTAVPGVSVRRGTEAVVGPKAKRLPRLIDTPSPYLLGVMDGAVATCRERGLRFYALWETNRGCPYSCSFCDWGSATMSTLRKFEDERLQDEIEWFARHDVEDLFICDANFGIMPRDLEIAHALAEARGELGAPRQVRVNFAKNSNDRVFDISKTWHDADLLMGTTLSMQSTDMDVLEAIDRKNIGLDNYRKLQQRYAAENIHTYTELILGLPMETARSFRDGIGSLLEAGNHEDLRVYELGILPNAPLNTPEKIEQYGLRTVPKRMYVERTPDDEAETFEMVMETNAMPRDAWVESFSFIQAVQFLHNGCYTRYLSIFLRQEHGIGYTRFYEGLQDYFTGRPDTVLGALYLRMRSLYHDYIDMPALPLANLVASQPDMAADLAPYGRRRGWTIDNWGWLRIATDFDRFHTELREYLATLGLDPAGDARLEDVLRFQQDVMLRPDYSPELGKSAEYAHDWPGYFAGGLLRPRRVRVAYGDQSFGANGRYRPVPGDLKAFTMAAIGTSYPVSRMGHFCHRFESAEVTSL 7kdy A 1.939 BS02 B12 A 1 N18 F22 V26 L30 L71 S72 Y74 V75 W76 G100 G101 P102 G124 E125 G126 E127 L199 D214 W215 G216 F247 C249 Y381 L386 L513 N11 F15 V19 L23 L64 S65 Y67 V68 W69 G93 G94 P95 G117 E118 G119 E120 L192 D207 W208 G209 F240 C242 Y374 L379 L506 ? 0003824,0005829,0008168,0031419,0032259,0046872,0051536,0051539 A0A6B9HEI0 35110734 702 RGRKVYFVGLNEYPFLPLVAGLLRTYAEQDERIAAAYDFQEPVFLVAPVQEMADGIVEPDVLALSCYVWNFRRQMKVAKLVKERYPNVLVVAGGPHVPDRPGNFFEKHPYVDVLAHGEGEVAFRELLATRLSDHPDYTAVPGVSVRRGTEAVVGPKAKRLPRLIDTPSPYLLGVMDGAVATCRERGLRFYALWETNRGCPYSCSFCDWGSATMSTLRKFEDERLQDEIEWFARHDVEDLFICDANFGIMPRDLEIAHALAEARGELGAPRQVRVNFAKNSNDRVFDISKTWHDADLLMGTTLSMQSTDMDVLEAIDRKNIGLDNYRKLQQRYAAENIHTYTELILGLPMETARSFRDGIGSLLEAGNHEDLRVYELGILPNAPLNTPEKIEQYGLRTVPKRMYVERPGTPDDEAETFEMVMETNAMPRDAWVESFSFIQAVQFLHNGCYTRYLSIFLRQEHGIGYTRFYEGLQDYFTGRPDTVLGALYLRMRSLYHDYIDMPALPLANLVASQPDMAADLAPYGRRRGWTIDNWGWLRIATDFDRFHTELREYLATLGLDARLEDVLRFQQDVMLRPDYSPELGKSAEYAHDWPGYFAGGLLRPRRVRVAYGDQSFGANGRYRPVPGDLKAFTMAAIGTSYPVSRMGHFCHRFESAEVTSL 7kdy B 1.939 BS02 B12 B 1 N18 F22 V26 L30 L71 S72 Y74 V75 W76 G100 G101 P102 G124 E125 G126 E127 L199 E201 D214 W215 G216 F247 C249 L386 N10 F14 V18 L22 L63 S64 Y66 V67 W68 G92 G93 P94 G116 E117 G118 E119 L191 E193 D206 W207 G208 F239 C241 L378 ? 0003824,0005829,0008168,0031419,0032259,0046872,0051536,0051539 A0A6B9HEI0 35110734 702 GRKVYFVGLNEYPFLPLVAGLLRTYAEQDERIAAAYDFQEPVFLVAPVQEMADGIVEPDVLALSCYVWNFRRQMKVAKLVKERYPNVLVVAGGPHVPDRPGNFFEKHPYVDVLAHGEGEVAFRELLATRLSDHPDYTAVPGVSVRRGTEAVVGPKAKRLPRLIDTPSPYLLGVMDGAVATCRERGLRFYALWETNRGCPYSCSFCDWGSATMSTLRKFEDERLQDEIEWFARHDVEDLFICDANFGIMPRDLEIAHALAEARGELGAPRQVRVNFAKNSNDRVFDISKTWHDADLLMGTTLSMQSTDMDVLEAIDRKNIGLDNYRKLQQRYAAENIHTYTELILGLPMETARSFRDGIGSLLEAGNHEDLRVYELGILPNAPLNTPEKIEQYGLRTVPKRMYVERPGTPDDEAETFEMVMETNAMPRDAWVESFSFIQAVQFLHNGCYTRYLSIFLRQEHGIGYTRFYEGLQDYFTGRPDTVLGALYLRMRSLYHDYIDMPALPLANLVASQPDMAADLAPYGRRRGWTIDNWGWLRIATDFDRFHTELREYLATLGLDPAGDARLEDVLRFQQDVMLRPDYSPELGKSAEYAHDWPGYFAGGLLRPRRVRVAYGDQSFGANGRYRPVPGDLKAFTMAAIGTSYPVSRMGHFCHRFESAEVTSL 7req A 2.2 BS02 B12 A 1 Y89 L119 A139 R207 E247 G333 W334 E370 A371 A373 G609 H610 D611 R612 G613 I617 S655 L657 G685 G686 Y705 T706 T709 Y86 L116 A136 R204 E244 G330 W331 E367 A368 A370 G606 H607 D608 R609 G610 I614 S652 L654 G682 G683 Y702 T703 T706 Y89 Y243 H244 K604 D608 H610 Y86 Y240 H241 K601 D605 H607 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 10387043 1800 LPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 7req C 2.2 BS02 B12 C 1 Y89 L119 A139 R207 E247 G333 W334 E370 A371 A373 G609 H610 D611 R612 G613 S655 L657 G659 G685 G686 V687 Y705 T706 T709 Y86 L116 A136 R204 E244 G330 W331 E367 A368 A370 G606 H607 D608 R609 G610 S652 L654 G656 G682 G683 V684 Y702 T703 T706 Y89 Y243 H244 K604 D608 H610 Y86 Y240 H241 K601 D605 H607 5.4.99.2 0003824,0004494,0005515,0005737,0016853,0016866,0019678,0031419,0046872 P11653 10387043 2800 LPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA 7ruu A 1.85 BS01 B12 A 1 L167 T168 A169 F170 I171 R186 S217 D218 F221 L79 T80 A81 F82 I83 R98 S129 D130 F133 2.5.1.- Q96EY8 34757128 305 KDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCCRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMK 7ruu A 1.85 BS02 B12 B 1 S162 Q163 L164 P165 P166 S74 Q75 L76 P77 P78 2.5.1.- Q96EY8 34757128 303 KDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCCRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMK 7ruu B 1.85 BS01 B12 B 1 L167 T168 A169 F170 I171 R186 S217 D218 F221 L75 T76 A77 F78 I79 R94 S125 D126 F129 2.5.1.- Q96EY8 34757128 303 DDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCCRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMK 7ruu C 1.85 BS01 B12 A 1 S162 Q163 L164 P165 P166 S72 Q73 L74 P75 P76 2.5.1.- Q96EY8 34757128 305 DDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATKYFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCCRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIY 7ruu C 1.85 BS02 B12 C 1 L167 T168 A169 F170 I171 R186 S217 D218 F221 L77 T78 A79 F80 I81 R96 S127 D128 F131 2.5.1.- Q96EY8 34757128 304 DDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATKYFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCCRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIY 7ruu D 1.85 BS01 B12 C 1 V86 D90 Q122 S126 V8 D12 Q41 S45 2.5.1.- Q96EY8 34757128 304 DDQVFEAVGTTDELSSAIGFALELVTHTFAEELQKIQCTLQDVGSALATFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCCRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMK 7ruu D 1.85 BS02 B12 D 1 L167 T168 A169 F170 I171 R186 S217 D218 F221 L72 T73 A74 F75 I76 R91 S122 D123 F126 2.5.1.- Q96EY8 34757128 303 DDQVFEAVGTTDELSSAIGFALELVTHTFAEELQKIQCTLQDVGSALATFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCCRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMK 7ruv A 2.1 BS01 B12 A 1 L167 T168 A169 F170 I171 R186 R190 S217 D218 F221 L79 T80 A81 F82 I83 R97 R101 S128 D129 F132 2.5.1.- Q96EY8 34757128 303 DDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPGGKISSALHFCRAVCRRAKRRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYM 7ruv A 2.1 BS02 B12 C 1 S162 Q163 L164 P165 P166 S74 Q75 L76 P77 P78 2.5.1.- Q96EY8 34757128 503 DDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPGGKISSALHFCRAVCRRAKRRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYM 7ruv B 2.1 BS01 B12 B 1 L167 T168 A169 F170 I171 R186 R190 S217 F221 L76 T77 A78 F79 I80 R94 R98 S125 F129 2.5.1.- Q96EY8 34757128 301 DDQVFEAVGTTDELSSAIGFALELVTGHTFAEELQKIQCTLQDVGSALATYTTFKAGPILELEQWIDKYTSQLPPLTAFILPGGKISSALHFCRAVCRRAKRRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYM 7ruv B 2.1 BS02 B12 D 1 V86 D90 Q122 S126 V8 D12 Q42 S46 2.5.1.- Q96EY8 34757128 301 DDQVFEAVGTTDELSSAIGFALELVTGHTFAEELQKIQCTLQDVGSALATYTTFKAGPILELEQWIDKYTSQLPPLTAFILPGGKISSALHFCRAVCRRAKRRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYM 7ruv C 2.1 BS01 B12 C 1 L167 T168 A169 F170 I171 R186 R190 S217 F221 L79 T80 A81 F82 I83 R98 R102 S129 F133 2.5.1.- Q96EY8 34757128 503 DDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAKRRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYM 7ruv D 2.1 BS01 B12 A 1 S162 Q163 L164 P165 P166 S74 Q75 L76 P77 P78 2.5.1.- Q96EY8 34757128 303 DDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAKRRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYM 7ruv D 2.1 BS02 B12 D 1 L167 T168 A169 F170 I171 R186 R190 S217 D218 F221 L79 T80 A81 F82 I83 R98 R102 S129 D130 F133 2.5.1.- Q96EY8 34757128 301 DDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAKRRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYM 7te2 A 2.25 BS01 B12 A 1 W54 D55 F61 V64 I68 Q104 H105 T106 G108 V112 L147 I148 T149 G151 S152 G179 G180 A181 T199 N200 W55 D56 F62 V65 I69 Q97 H98 T99 G101 V105 L140 I141 T142 G144 S145 G172 G173 A174 T192 N193 ? 0031419,0046872 D5ANS8 35630357 301 SLQTVLVNRMVELATGPELGAMDLLFDEFRAAHVPVEEMATHYIPEAARQIGAAWDSDRIGFAQVTIAISRLQELLHALQTLVTGATVLLIVPPGEQHTLGALIVAMELRRRGVSVRIVFAPGLSDLSRLMATTRFDAALITVGSMDRVEICAKLVKTLSSLTKGRMRVAIGGAIVSQRAEALARTGADLVTNDLSLVISEFSLV 7xrk A 2.3 BS03 B12 B 1 Y226 D234 Q267 M268 Y225 D233 Q266 M267 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 35974426 301 RSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNED 7xrk B 2.3 BS01 B12 B 1 D112 K135 T137 L148 L153 P155 Q156 A157 R193 Y196 Q197 S200 D67 K90 T92 L103 L108 P110 Q111 A112 R148 Y151 Q152 S155 4.2.1.28 Q59471 35974426 301 GFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVA 7xrk D 2.3 BS03 B12 E 1 Y226 Q267 M268 Y226 Q267 M268 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 35974426 301 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNED 7xrk E 2.3 BS01 B12 E 1 D112 K135 T137 L148 N150 L153 P155 Q156 A157 R193 Y196 Q197 S200 D67 K90 T92 L103 N105 L108 P110 Q111 A112 R148 Y151 Q152 S155 4.2.1.28 Q59471 35974426 301 GFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVA 7xrl A 1.75 BS03 B12 B 1 Y226 G235 Q267 M268 Y226 G235 Q267 M268 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 35974426 301 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNE 7xrl B 1.75 BS01 B12 B 1 K135 T137 L148 L153 P155 Q156 A157 P158 R193 Y196 S200 K90 T92 L103 L108 P110 Q111 A112 P113 R148 Y151 S155 4.2.1.28 Q59471 35974426 301 GFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 7xrl D 1.75 BS03 B12 E 1 Y226 D234 G235 Q267 M268 Y226 D234 G235 Q267 M268 4.2.1.28 0003824,0016829,0016836,0031419,0046872,0050215 Q59470 35974426 301 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNEID 7xrl E 1.75 BS01 B12 E 1 K135 T137 L148 L153 P155 Q156 A157 P158 R193 Y196 Q197 S200 K90 T92 L103 L108 P110 Q111 A112 P113 R148 Y151 Q152 S155 4.2.1.28 Q59471 35974426 301 GFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVA 7xrm A 2.13 BS02 B12 B 1 P194 V195 A226 Q246 S247 E257 F258 F329 I330 M401 L402 P194 V195 A226 Q246 S247 E257 F258 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 35974426 301 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 7xrm B 2.13 BS01 B12 B 1 L169 R206 V207 E228 R229 Y241 E253 C258 S260 L127 R164 V165 E186 R187 Y199 E211 C216 S218 4.3.1.7 0006520,0008851 P19636 35974426 301 HALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 7xrm C 2.13 BS02 B12 D 1 P194 S247 F258 F329 I330 M401 L402 P194 S247 F258 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 35974426 301 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 7xrm D 2.13 BS01 B12 D 1 L169 R206 V207 K208 E228 R229 Y241 E253 R256 S260 L126 R163 V164 K165 E185 R186 Y198 E210 R213 S217 4.3.1.7 0006520,0008851 P19636 35974426 301 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 7xrn A 2.07 BS02 B12 B 1 N193 P194 T196 A226 H227 Q246 E257 F258 F329 I330 M401 L402 N193 P194 T196 A226 H227 Q246 E257 F258 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 35974426 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 7xrn B 2.07 BS01 B12 B 1 R206 V207 E228 R229 Y241 E253 R256 C258 S260 R163 V164 E185 R186 Y198 E210 R213 C215 S217 4.3.1.7 0006520,0008851 P19636 35974426 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 7xrn C 2.07 BS02 B12 D 1 P194 V195 A226 H227 Q246 S247 E257 F258 F329 I330 M401 L402 P194 V195 A226 H227 Q246 S247 E257 F258 F329 I330 M401 L402 4.3.1.7 0005829,0006520,0008851,0009350,0016829,0031419,0031469,0031471,0046336 P0AEJ6 35974426 601 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 7xrn D 2.07 BS01 B12 D 1 L169 R206 V207 E228 R229 Y241 E253 R256 C258 S260 L126 R163 V164 E185 R186 Y198 E210 R213 C215 S217 4.3.1.7 0006520,0008851 P19636 35974426 601 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR 8c31 A 1.8 BS01 B12 A 1 L124 G128 H132 E141 S145 R176 H177 E178 I179 G180 L183 S222 L225 G247 G248 Q249 M264 D266 L267 L47 G51 H55 E64 S68 R99 H100 E101 I102 G103 L106 S142 L145 G167 G168 Q169 M184 D186 L187 ? 0031419,0046872 Q746J7 37604813 302 VRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRARLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c31 B 1.8 BS01 B12 B 1 L121 L124 R125 G128 W131 H132 E141 S145 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 L267 L40 L43 R44 G47 W50 H51 E60 S64 R95 H96 E97 I98 G99 S141 L144 G166 G167 Q168 M183 L186 ? 0031419,0046872 Q746J7 37604813 302 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRG 8c31 C 1.8 BS01 B12 C 1 L121 L124 R125 G128 E141 S145 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L44 L47 R48 G51 E64 S68 R99 H100 E101 I102 G103 S145 L148 G170 G171 Q172 M187 D189 L190 ? 0031419,0046872 Q746J7 37604813 302 VRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c31 D 1.8 BS01 B12 D 1 L121 L124 R125 G128 E141 S145 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L40 L43 R44 G47 E60 S64 R95 H96 E97 I98 G99 S141 L144 G166 G167 Q168 M183 D185 L186 ? 0031419,0046872 Q746J7 37604813 702 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW 8c32 A 2.2 BS01 B12 A 1 L121 L124 G128 W131 E141 S145 R176 H177 E178 I179 G180 L183 S222 L225 G247 G248 Q249 M264 L267 L40 L43 G47 W50 E60 S64 R95 H96 E97 I98 G99 L102 S141 L144 G166 G167 Q168 M183 L186 ? 0031419,0046872 Q746J7 37604813 302 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c32 B 2.2 BS01 B12 B 1 L121 L124 W131 E141 S145 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 L267 L41 L44 W51 E61 S65 R96 H97 E98 I99 G100 S142 L145 G167 G168 Q169 M184 L187 ? 0031419,0046872 Q746J7 37604813 301 EDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 8c32 C 2.2 BS01 B12 C 1 L121 L124 E141 S145 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L44 L47 E64 S68 R99 H100 E101 I102 G103 S145 L148 G170 G171 Q172 M187 D189 L190 ? 0031419,0046872 Q746J7 37604813 301 VRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c32 D 2.2 BS01 B12 D 1 L121 L124 R125 G128 E141 S145 R176 H177 E178 I179 S222 L225 G247 G248 Q249 M264 L267 L40 L43 R44 G47 E60 S64 R95 H96 E97 I98 S141 L144 G166 G167 Q168 M183 L186 ? 0031419,0046872 Q746J7 37604813 301 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW 8c33 A 2.25 BS01 B12 A 1 R125 E129 W131 H132 E141 S145 H177 G180 S222 V224 L225 S226 G247 G248 Q249 M264 L267 R46 E50 W52 H53 E62 S66 H98 G101 S143 V145 L146 S147 G168 G169 Q170 M185 L188 ? 0031419,0046872 Q746J7 37604813 301 PEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW 8c33 B 2.25 BS01 B12 B 1 L124 R125 E129 W131 H132 S145 H177 S222 V224 L225 S226 G247 G248 Q249 M264 E265 L267 L47 R48 E52 W54 H55 S68 H100 S145 V147 L148 S149 G170 G171 Q172 M187 E188 L190 ? 0031419,0046872 Q746J7 37604813 301 VRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 8c33 C 2.25 BS01 B12 C 1 L124 G128 E129 W131 H132 H177 L221 S222 G247 G248 Q249 M264 L267 L46 G50 E51 W53 H54 H99 L143 S144 G169 G170 Q171 M186 L189 ? 0031419,0046872 Q746J7 37604813 301 RPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c33 D 2.25 BS01 B12 D 1 L124 G128 E129 W131 H132 E141 S145 H177 S222 V224 L225 S226 G247 G248 Q249 M264 L267 L46 G50 E51 W53 H54 E63 S67 H99 S144 V146 L147 S148 G169 G170 Q171 M186 L189 ? 0031419,0046872 Q746J7 37604813 301 RPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLP 8c34 A 1.82 BS01 B12 A 1 R125 E129 W131 H132 E141 S145 H177 G180 S222 V224 L225 S226 G247 G248 Q249 M264 L267 R48 E52 W54 H55 E64 S68 H100 G103 S145 V147 L148 S149 G170 G171 Q172 M187 L190 ? 0031419,0046872 Q746J7 37604813 301 VRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c34 B 1.82 BS01 B12 B 1 L124 R125 E129 W131 H132 E141 S145 H177 G180 S222 L225 S226 G247 G248 Q249 M264 E265 L267 L47 R48 E52 W54 H55 E64 S68 H100 G103 S145 L148 S149 G170 G171 Q172 M187 E188 L190 ? 0031419,0046872 Q746J7 37604813 301 VRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 8c34 C 1.82 BS01 B12 C 1 G128 E129 W131 H132 E141 H177 S222 L225 G247 G248 Q249 M264 L267 G51 E52 W54 H55 E64 H100 S145 L148 G170 G171 Q172 M187 L190 ? 0031419,0046872 Q746J7 37604813 301 VRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c34 D 1.82 BS01 B12 D 1 L124 G128 E129 W131 H132 E141 S145 H177 G180 S222 L225 S226 G247 G248 Q249 M264 L267 L46 G50 E51 W53 H54 E63 S67 H99 G102 S144 L147 S148 G169 G170 Q171 M186 L189 ? 0031419,0046872 Q746J7 37604813 301 RPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 8c35 A 2.1 BS01 B12 A 1 L121 L124 G128 E141 R176 H177 E178 I179 G180 L183 S222 L225 G247 G248 Q249 M264 D266 L267 L41 L44 G48 E61 R96 H97 E98 I99 G100 L103 S142 L145 G167 G168 Q169 M184 D186 L187 ? 0031419,0046872 Q746J7 37604813 301 EDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWARGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c35 B 2.1 BS01 B12 B 1 L124 R125 G128 E141 G174 E175 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 L267 L43 R44 G47 E60 G93 E94 R95 H96 E97 I98 G99 S141 L144 G166 G167 Q168 M183 L186 ? 0031419,0046872 Q746J7 37604813 301 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWARGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW 8c35 C 2.1 BS01 B12 C 1 L121 L124 R125 G128 E141 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L39 L42 R43 G46 E59 R94 H95 E96 I97 G98 S140 L143 G165 G166 Q167 M182 D184 L185 ? 0031419,0046872 Q746J7 37604813 301 LGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWARGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c35 D 2.1 BS01 B12 D 1 R125 G128 E141 S145 G174 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 R44 G47 E60 S64 G93 R95 H96 E97 I98 G99 S141 L144 G166 G167 Q168 M183 D185 L186 ? 0031419,0046872 Q746J7 37604813 301 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWARGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c36 A 2.0 BS01 B12 A 1 L121 L124 G128 W131 H142 R176 H177 E178 I179 G180 S222 L225 G247 G248 M264 D266 L267 L40 L43 G47 W50 H61 R95 H96 E97 I98 G99 S141 L144 G166 G167 M183 D185 L186 ? 0031419,0046872 Q746J7 37604813 301 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWARGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c36 B 2.0 BS01 B12 B 1 G128 E141 H142 R176 H177 E178 I179 G180 S222 V224 L225 G247 G248 M264 L267 G47 E60 H61 R95 H96 E97 I98 G99 S141 V143 L144 G166 G167 M183 L186 ? 0031419,0046872 Q746J7 37604813 301 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWARGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 8c36 C 2.0 BS01 B12 C 1 L121 L124 R125 G128 H142 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L39 L42 R43 G46 H60 R94 H95 E96 I97 G98 S140 L143 G165 G166 Q167 M182 D184 L185 ? 0031419,0046872 Q746J7 37604813 301 LGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWARGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW 8c36 D 2.0 BS01 B12 D 1 L121 L124 G128 H142 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L40 L43 G47 H61 R95 H96 E97 I98 G99 S141 L144 G166 G167 Q168 M183 D185 L186 ? 0031419,0046872 Q746J7 37604813 301 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWARGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW 8c37 A 2.15 BS01 B12 A 1 E129 W131 E141 S145 R176 H177 I179 S222 L225 G247 G248 Q249 M264 D266 L267 E50 W52 E62 S66 R97 H98 I100 S143 L146 G168 G169 Q170 M185 D187 L188 ? 0031419,0046872 Q746J7 37604813 301 PEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWARGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c37 B 2.15 BS01 B12 B 1 L124 R125 G128 E129 S145 H177 G180 S222 L225 S226 G247 G248 Q249 M264 L267 L43 R44 G47 E48 S64 H96 G99 S141 L144 S145 G166 G167 Q168 M183 L186 ? 0031419,0046872 Q746J7 37604813 301 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWARGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLP 8c37 C 2.15 BS01 B12 C 1 L124 R125 G128 E141 H142 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 L267 L47 R48 G51 E64 H65 R99 H100 E101 I102 G103 S145 L148 G170 G171 Q172 M187 L190 ? 0031419,0046872 Q746J7 37604813 301 VRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWARGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c37 D 2.15 BS01 B12 D 1 L124 R125 G128 W131 E141 H142 G174 R176 H177 E178 G180 S222 L225 G247 G248 Q249 M264 L267 L43 R44 G47 W50 E60 H61 G93 R95 H96 E97 G99 S141 L144 G166 G167 Q168 M183 L186 ? 0031419,0046872 Q746J7 37604813 301 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWARGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 8c73 A 1.7 BS01 B12 A 1 L121 L124 R125 G128 E141 S145 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L41 L44 R45 G48 E61 S65 R96 H97 E98 I99 G100 S142 L145 G167 G168 Q169 M184 D186 L187 ? 0031419,0046872 Q53W62 37604813 402 EDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW 8c73 B 1.7 BS01 B12 B 1 L121 L124 R125 G128 E141 S145 R176 H177 E178 I179 G180 L183 S222 L225 G247 G248 Q249 D266 L267 L41 L44 R45 G48 E61 S65 R96 H97 E98 I99 G100 L103 S142 L145 G167 G168 Q169 D186 L187 ? 0031419,0046872 Q53W62 37604813 301 EDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLP 8c73 C 1.7 BS01 B12 C 1 L121 L124 R125 G128 E141 R176 H177 E178 I179 G180 S222 V224 L225 G247 G248 Q249 M264 D266 L267 L44 L47 R48 G51 E64 R99 H100 E101 I102 G103 S145 V147 L148 G170 G171 Q172 M187 D189 L190 ? 0031419,0046872 Q53W62 37604813 301 VRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW 8c73 D 1.7 BS01 B12 D 1 L121 R125 G128 E141 S145 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L40 R44 G47 E60 S64 R95 H96 E97 I98 G99 S141 L144 G166 G167 Q168 M183 D185 L186 ? 0031419,0046872 Q53W62 37604813 301 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 8c76 A 2.5 BS01 B12 A 1 L121 L124 R125 W131 H132 E141 H177 S222 V224 L225 S226 G247 G248 Q249 M264 D266 L267 L44 L47 R48 W54 H55 E64 H100 S145 V147 L148 S149 G170 G171 Q172 M187 D189 L190 ? 0031419,0046872 Q53W62 37604813 301 VRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c76 B 2.5 BS01 B12 B 1 L124 R125 G128 E129 W131 H132 E141 H177 S222 L225 G247 G248 Q249 M264 L267 L43 R44 G47 E48 W50 H51 E60 H96 S141 L144 G166 G167 Q168 M183 L186 ? 0031419,0046872 Q53W62 37604813 301 DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 8c76 C 2.5 BS01 B12 C 1 L124 R125 G128 W131 H132 E141 H177 S222 L225 G247 G248 Q249 M264 L267 L47 R48 G51 W54 H55 E64 H100 S145 L148 G170 G171 Q172 M187 L190 ? 0031419,0046872 Q53W62 37604813 301 VRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 8c76 D 2.5 BS01 B12 D 1 L124 R125 G128 E129 H177 S222 L225 G247 G248 Q249 M264 L267 L47 R48 G51 E52 H100 S145 L148 G170 G171 Q172 M187 L190 ? 0031419,0046872 Q53W62 37604813 301 VRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 8c7p A 3.0 BS01 B12 A 1 R25 S26 H28 W40 D67 A70 V76 S77 F79 C80 A84 Y85 T131 F135 F142 Y157 M161 R22 S23 H25 W37 D64 A67 V73 S74 F76 C77 A81 Y82 T128 F132 F139 Y154 M158 ? 0016020 Q3SFD8 38733996 201 NLTRRQQIAIGFVLVLMMLLTRSHHWASIHSLPDASWAIFFLLGVYVRALWVVPALIAASVVIDYVAITWGGVSDFCVSPAYWLLIPAYLALFAGGRFYARGHSLSLLGLFRLAGVALAVVAVAQLLTTGGFYFYSGRFADPTLAGLVLRLEKYFPPMLGTFALYVGLAATVHVALAAV 8dyj B 2.2 BS01 B12 B 1 F101 L103 H106 A123 V190 R191 H228 E231 G318 W319 E355 G358 L359 G589 H590 D591 R592 G593 I597 S635 L637 A639 G665 G666 V667 F685 G686 T689 F102 L104 H107 A124 V191 R192 H229 E232 G319 W320 E356 G359 L360 G590 H591 D592 R593 G594 I598 S636 L638 A640 G666 G667 V668 F686 G687 T690 5.4.99.2 0003824,0003924,0004494,0005515,0005737,0005739,0005759,0006790,0009791,0016853,0016866,0019678,0031419,0042802,0042803,0043547,0046872,0050667,0072341,1901290 P22033 36888659 801 QPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDTVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLE 8dyl B 1.9 BS01 B12 B 1 A160 V227 R228 E268 W356 E392 A393 L394 G395 G626 H627 D628 R629 G630 I634 S672 L674 A675 A676 G702 G703 F722 G723 T726 A125 V192 R193 E233 W321 E357 A358 L359 G360 G582 H583 D584 R585 G586 I590 S628 L630 A631 A632 G658 G659 F678 G679 T682 5.4.99.2 0003824,0003924,0004494,0005515,0005737,0005739,0005759,0006790,0009791,0016853,0016866,0019678,0031419,0042802,0042803,0043547,0046872,0050667,0072341,1901290 P22033 36888659 801 QQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQ 8g3h A 3.6 BS01 B12 A 1 Q364 T366 S367 F711 V721 K729 G756 V758 H759 D760 I761 G762 V766 M803 S804 L806 V808 I831 L832 G833 G834 A835 Y854 A855 E856 D857 Q328 T330 S331 F675 V685 K693 G720 V722 H723 D724 I725 G726 V730 M767 S768 L770 V772 I795 L796 G797 G798 A799 Y818 A819 E820 D821 2.1.1.13 0005829,0008168,0008270,0008705,0009086,0031419,0032259,0042558,0044237,0046653,0046872,0050667 A0A0A2XCD7 37339208 1202 RRFPYLRALSQRVLVFDGAMGTELQKRDLTPEDYGEEAYYGCPEVLNRTRPDVVREIHLSYLEAGAEVIETNSFGALRHVLAEYGLGEEAEELAYRAARIAKEAAEPYGAFVAGALGPGTKLVSLGQISWEELFSAYKEAVRGLVRGGVDLILLETAQDILQVRCAVLAAREAMAELGVELPLQVQVTFEATGTMLVGTDEQAALAALESLPIDVVGMNCATGPDLMDAKIRYFAQESTRFVACLPNAGLPRNEGGRVVYDLTPEELARWHLKFVTEYGVNAVGGCCGTGPEHIRKVAEAVGGRPSPVHKTAFPPQVASLYQAVPLRQETSLLLVGERLNATGSKRFRELLFAGDLEGILALAQEQVAEGAHVLDLSVAWTGRDELEDMKRVLSKLATGVTVPFMVDSTSPEVMEEALKRLPGRAILNSANLEDGLEKFDRVASLAKAHGAALVALAIDEEGMAKTRVKKVEVALRMYERLTEHHGLRPEDLLFDLLTFPITQGDEETRPLARETLLALEELRERLPGVGFVLGVSNVSFGLKPKARRVLNSVFLDEARKKGLTAAIVDAGKILPISQIPEEAYALALDLIYDRREGQDPLFAFIRFFEEHKEVLAEDKEAFQALPVEERLRRRVLEGKRVGLEEDLAEALGRMRPLEIINGPLLEAMKEVGELFGAGKMQLPFVLQAAEVMKQAVAYLEPHMEKKGEGKGKLVLATVKGDVHDIGKNLVDIILTNNGYTVYNLGIKVPIEEMLKAVDEVKPHALGMSGLLVKSTQVMKENLEYMRARGYTLPVILGGAALTRAYVEELRSIYPEVYYAEDAFEGLALMEELTGHRPKDLT 8ixt A 1.2 BS01 B12 A 1 G103 S104 Y155 D197 N245 Y247 S248 M289 Q292 L376 S377 G378 P379 Y380 L381 Y394 W395 Q396 L397 L405 L406 G408 G80 S81 Y129 D171 N219 Y221 S222 M263 Q266 L350 S351 G352 P353 Y354 L355 Y368 W369 Q370 L371 L379 L380 G382 ? 0005576,0005615,0006824,0009897,0015889,0031419,0046872,0140355 Q9R0D6 38636663 501 DDKGEFCVIPKMDGQLVEKLGQRLLPWMDRLSSEQLNPSIYVGLRLSSMQAGTKENLYLHNLKLHYQQCLLGCQTKISGGSLALYLLALRANCELLGGDRMVSQLKWFLEDEKKAIGHHHEGHPHTSYYQYGLSILALCVHRKRVHDSVVGKLLYAVEHDYFTYQGHLSVDTEAMAGLAFTCLERFNFNSDLRPRITTAIETVREKILKAQAPEGYFGNIYSTPLALQMLMTSPGVGLGPACLKARKSLLLSLQDGAFQNPMMISQLLPVLNHKTYLNLISPDCQAPRVMLVPATEDPVHLSEVSVTLKVSSVLPPYERTVSVFAGASLEDVLNRARDLGEFTYGTQASLSGPYLTSVLGKEAGDREYWQLLRVPDTPLLQGIADYKPKNGETIELRLVKM 8ixu A 1.3 BS01 B12 A 1 G103 S104 Y155 D197 N245 Y247 S248 M289 Q292 L376 S377 G378 P379 Y380 L381 Y394 W395 Q396 L397 L405 L406 G408 G76 S77 Y128 D170 N218 Y220 S221 M262 Q265 L349 S350 G351 P352 Y353 L354 Y367 W368 Q369 L370 L378 L379 G381 ? 0005576,0005615,0006824,0009897,0015889,0031419,0046872,0140355 Q9R0D6 38636663 501 GEFCVIPKMDGQLVEKLGQRLLPWMDRLSSEQLNPSIYVGLRLSSMQAGTKENLYLHNLKLHYQQCLGCQTKISGGSLALYLLALRANCELLGSRKGDRMVSQLKWFLEDEKKAIGHHHEGHPHTSYYQYGLSILALCVHRKRVHDSVVGKLLYAVEHDYFTYQGHLSVDTEAMAGLAFTCLERFNFNSDLRPRITTAIETVREKILKAQAPEGYFGNIYSTPLALQMLMTSPGVGLGPACLKARKSLLLSLQDGAFQNPMMISQLLPVLNHKTYLNLISPDCQAPRVMLVPATEDPVHLSEVSVTLKVSSVLPPYERTVSVFAGASLEDVLNRARDLGEFTYGTQASLSGPYLTSVLGKEAGDREYWQLLRVPDTPLLQGIADYKPKNGETIELRLVKM 8j2w A 1.7 BS01 B12 A 1 A51 Q54 G58 Q62 E71 T75 E79 W107 H108 A109 L110 P111 I114 V115 A151 L152 S153 L156 L178 V179 G180 G181 L182 P201 T202 A203 W296 A45 Q48 G52 Q56 E65 T69 E73 W101 H102 A103 L104 P105 I108 V109 A145 L146 S147 L150 L172 V173 G174 G175 L176 P195 T196 A197 W281 ? 0031419,0046872 A0A5Q0H231 38548733 401 DILAAGREELMAALAEGDEHAAVDLAMRLLDGGVPADVVLLELVADAQVEIGVLWQANRWSVAQEHAATAISERVIAAVGDRAAAAPTRGHVVVACLDGEWHALPARIVAEVLRGRGWRVTFLGASVPAAHLVPYLEEHGPDAVALSCTLPRGLPRADQVVAACRATGTPVLVGGLGFGPDGRWARVLGAGTWAPTARAAADLLDRPEPRPADPEYAALRARRAELVDAGLAALHEWFPPLRDYDARRLDATLDDLGDIVDHLAASVYVDDPELFGEFVTWTAEVLAARGVSPASVEVALEAIARVLDDHPRTRHHLDHGRRALAAHLEH 8j2w B 1.7 BS01 B12 B 1 A51 Q54 G58 Q62 E71 T75 W107 H108 A109 L110 P111 V115 A151 L152 S153 L156 L178 V179 G180 G181 A200 P201 T202 A203 W296 A45 Q48 G52 Q56 E65 T69 W101 H102 A103 L104 P105 V109 A145 L146 S147 L150 L172 V173 G174 G175 A194 P195 T196 A197 W280 ? 0031419,0046872 A0A5Q0H231 38548733 403 DILAAGREELMAALAEGDEHAAVDLAMRLLDGGVPADVVLLELVADAQVEIGVLWQANRWSVAQEHAATAISERVIAAVGDRAAAAPTRGHVVVACLDGEWHALPARIVAEVLRGRGWRVTFLGASVPAAHLVPYLEEHGPDAVALSCTLPRGLPRADQVVAACRATGTPVLVGGLGFGPDGRWARVLGAGTWAPTARAAADLLDRPERPADPEYAALRARRAELVDAGLAALHEWFPPLRDYDARRLDATLDDLGDIVDHLAASVYVDDPELFGEFVTWTAEVLAARGVSPASVEVALEAIARVLDDHPRTRHHLDHGRRALAAHLEH 8j2x A 1.98 BS01 B12 A 1 A51 Q54 G58 W61 Q62 W107 H108 A109 L110 P111 V115 A151 L152 S153 L156 L178 V179 G180 G181 A200 P201 T202 A203 W296 A46 Q49 G53 W56 Q57 W102 H103 A104 L105 P106 V110 A146 L147 S148 L151 L173 V174 G175 G176 A195 P196 T197 A198 W287 ? 0031419,0046872 A0A5Q0H231 38548733 401 VDILAAGREELMAALAEGDEHAAVDLAMRLLDGGVPADVVLLELVADAQVEIGVLWQANRWSVAQEHAATAISERVIAAVGDRAAAAPTRGHVVVACLDGEWHALPARIVAEVLRGRGWRVTFLGASVPAAHLVPYLEEHGPDAVALSCTLPRGLPRADQVVAACRATGTPVLVGGLGFGPDGRWARVLGAGTWAPTARAAADLLDRPEWPPAPPRPADPEYAALRARRAELVDAGLAALHEWFPPLRDYDARRLDATLDDLGDIVDHLAASVYVDDPELFGEFVTWTAEVLAARGVSPASVEVALEAIARVLDDHPRTRHHLDHGRRALAAHLEHH 8j2y A 2.3 BS01 B12 A 1 A46 Q49 R50 E66 D101 W102 H103 L105 S106 M109 F110 S148 F154 V174 G175 G176 R177 W291 A45 Q48 R49 E65 D100 W101 H102 L104 S105 M108 F109 S147 F153 V173 G174 G175 R176 W286 ? 0031419,0046872 A0A349B205 38548733 401 EAPASYVEPYLGDAIVGNRRPAVRLTLDLLDHRVPEADIVEDLLAAAQREVGERWYRNELSPADEHLASGVAGAALDALAAELPPPTRDGLVVVACAEGDWHSLSAQMFGETLRASGFDVSVLGASTPRTAVVDFLTRAGGDSLAVSCNMPIFFPGVAQLINAAHEIGVPVIVGGRAFGDDDRRAARLGADAWAAGASEAAEILAGWHARRPEVGSEPAPLDGAALRLFAASSTLATATVDELTASPILDADQVDQLREHLVFAVQFLAAARLVDDDSIFEDFLVWIDELLRTRDVPREVLAAGLEGLRAKVIAVDPGATRLLDAAW 8j2y B 2.3 BS01 B12 B 1 A46 Q49 R50 G53 D101 W102 H103 S104 L105 S106 M109 F110 V147 S148 V174 G175 G176 R177 A195 W291 A45 Q48 R49 G52 D100 W101 H102 S103 L104 S105 M108 F109 V146 S147 V173 G174 G175 R176 A194 W287 ? 0031419,0046872 A0A349B205 38548733 401 EAPASYVEPYLGDAIVGNRRPAVRLTLDLLDHRVPEADIVEDLLAAAQREVGERWYRNELSPADEHLASGVAGAALDALAAELPPPTRDGLVVVACAEGDWHSLSAQMFGETLRASGFDVSVLGASTPRTAVVDFLTRAGGDSLAVSCNMPIFFPGVAQLINAAHEIGVPVIVGGRAFGDDDRRAARLGADAWAAGASEAAEILAGWHARRPEVGSEPAPLDGAALRLFAASSTLATATVDELTASPILLDADQVDQLREHLVFAVQFLAAARLVDDDSIFEDFLVWIDELLRTRDVPREVLAAGLEGLRAKVIAVDPGATRLLDAA 8ovv A 2.26 BS01 B12 A 1 R25 S26 H28 W29 D67 A70 V76 F79 C80 A84 T131 T132 F135 F142 R153 K156 Y157 M161 R21 S22 H24 W25 D63 A66 V72 F75 C76 A80 T124 T125 F128 F135 R146 K149 Y150 M154 ? 0016020 Q3SFD8 201 LTRRQQIAIGFVLVLMMLLTRSHHWASIHSLPDASWAIFFLLGVYVRALWVVPALIAASVVIDYVAITWGGVSDFCVSPAYWLLIPAYLALFAGGRFYARGHSLGLFRLAGVALAVVAVAQLLTTGGFYFYSGRFADPTLAGLVLRLEKYFPPMLGTFALYVGLAATVHVALAAV 8ptd A 1.6 BS01 B12 A 1 E40 L42 F43 N78 R124 G179 L180 Y182 N210 R227 I231 Y273 Y325 E19 L21 F22 N57 R103 G158 L159 Y161 N189 R206 I210 Y252 Y304 Q8A7N4 402 ESNGDVFETGTAEMYILSEGLFNQNNSSLARYSFNRQRCTNNYFSANNQRGLGDTANDIAIYGNKIYVVVNVSSTVEVIDFPTGKSIRQISMLRDNGSSRQPRAIAFDKDKAYICSYDGTVARIDTTSLEIEEIVTVGRNAEDICVQNGKLYVSNSGGLDYSGPGVDTTVSVIDITTFKETKKIEVGPNPGKILPGLEEAVYVVTRGTDIEAGDYHLVKIDSRTDAVAITYDEKVLSFAIDGPIAYLYTYDYQTKDSANKVFDLNAGTVIRDNFITDGTAIQTPFSIQLNPFSGNIYITEAYNYTVKGDVLCFNQQGQLQYRLNDIGLNPNTVVFSDKASQNE 8sse A 3.15 BS01 B12 A 1 H761 G764 V768 S806 L809 V810 I833 G835 G836 A837 H1083 V1087 S1129 F1130 G1131 Y1132 Q1141 L1163 E1166 A1168 S1170 H97 G100 V104 S142 L145 V146 I169 G171 G172 A173 H405 V409 S451 F452 G453 Y454 Q463 L485 E488 A490 S492 2.1.1.13 0008705,0009086,0031419,0046872 Q5SKM5 37821448 1201 PLLERLKRRVVEGRKQGLEADLEEALKAGHKPLDLINGPLLAGMKEVGDLFGAGKMQLPFVLQAAEVMKRAVAYLEPHMEKEGKGTLVLATVKGDVHDIGKNLVDIILSNNGYRVVNLGIKVPIEEILKAVEAHKPHAVGMSGLLVKSTLVMKENLEYMRDRGYTLPVILGGAALTRSYVEELRAIYPNVYYAEDAFEGLRLMEELTGHAPPELTRPRARPVGEAPAVPRPPFFGVRVEEGLDLATIAHYVNKLALYRGQWGYSRKGLSREAWQALVEREAEPVFQRLLKEAMAEGWLEPKVLYGFFPVAREGEELLVFSPETGEVLERFRFPRQKGGGLSLVDYFRPRFAAPLGDEADWMPKEAFRAGARDVLGVQLVTMGEAPSRKAQALFASGAYQDYLFVHGFSVEMTEALAEYWHKRMRQMWGIAHQDATEIQKLFQQGYQGARYSFGYPACPDLADQAKLDRLMGFHRVGVRLTENFQLEPEHATSALVVHHPEARYFSVD 8sse B 3.15 BS01 B12 B 1 H761 G764 V768 M805 S806 L809 I833 G835 G836 A837 A860 H1083 S1129 F1130 G1131 Y1132 L1163 E1166 T1169 S1170 H97 G100 V104 M141 S142 L145 I169 G171 G172 A173 A196 H404 S450 F451 G452 Y453 L484 E487 T490 S491 2.1.1.13 0008705,0009086,0031419,0046872 Q5SKM5 37821448 1201 PLLERLKRRVVEGRKQGLEADLEEALKAGHKPLDLINGPLLAGMKEVGDLFGAGKMQLPFVLQAAEVMKRAVAYLEPHMEKEGKGTLVLATVKGDVHDIGKNLVDIILSNNGYRVVNLGIKVPIEEILKAVEAHKPHAVGMSGLLVKSTLVMKENLEYMRDRGYTLPVILGGAALTRSYVEELRAIYPNVYYAEDAFEGLRLMEELTGHAPPELTRRARPVGEAPAVPRPPFFGVRVEEGLDLATIAHYVNKLALYRGQWGYSRKGLSREAWQALVEREAEPVFQRLLKEAMAEGWLEPKVLYGFFPVAREGEELLVFSPETGEVLERFRFPRQKGGGLSLVDYFRPRFAAPLGDEADWMPKEAFRAGARDVLGVQLVTMGEAPSRKAQALFASGAYQDYLFVHGFSVEMTEALAEYWHKRMRQMWGIAHQDATEIQKLFQQGYQGARYSFGYPACPDLADQAKLDRLMGFHRVGVRLTENFQLEPEHATSALVVHHPEARYFSVD 8sse C 3.15 BS01 B12 C 1 H761 G764 V768 M805 S806 L808 L809 V810 I833 G835 G836 A837 A860 Q938 V1087 S1129 F1130 G1131 Y1132 Q1141 Q1162 L1163 E1166 A1168 S1170 H97 G100 V104 M141 S142 L144 L145 V146 I169 G171 G172 A173 A196 Q260 V409 S451 F452 G453 Y454 Q463 Q484 L485 E488 A490 S492 2.1.1.13 0008705,0009086,0031419,0046872 Q5SKM5 37821448 1201 PLLERLKRRVVEGRKQGLEADLEEALKAGHKPLDLINGPLLAGMKEVGDLFGAGKMQLPFVLQAAEVMKRAVAYLEPHMEKEGKGTLVLATVKGDVHDIGKNLVDIILSNNGYRVVNLGIKVPIEEILKAVEAHKPHAVGMSGLLVKSTLVMKENLEYMRDRGYTLPVILGGAALTRSYVEELRAIYPNVYYAEDAFEGLRLMEELTGHAPPELTRPRARPVGEAPAVPRPPFFGVRVEEGLDLATIAHYVNKLALYRGQWGYSRKGLSREAWQALVEREAEPVFQRLLKEAMAEGWLEPKVLYGFFPVAREGEELLVFSPETGEVLERFRFPRQKGGGLSLVDYFRPRFAAPLGDEADWMPKEAFRAGARDVLGVQLVTMGEAPSRKAQALFASGAYQDYLFVHGFSVEMTEALAEYWHKRMRQMWGIAHQDATEIQKLFQQGYQGARYSFGYPACPDLADQAKLDRLMGFHRVGVRLTENFQLEPEHATSALVVHHPEARYFSVD 8sse D 3.15 BS01 B12 D 1 H761 I763 G764 V768 M805 S806 L809 V810 I833 G835 G836 A837 A860 Q938 S1129 F1130 G1131 Y1132 Q1162 L1163 E1166 A1168 T1169 S1170 H97 I99 G100 V104 M141 S142 L145 V146 I169 G171 G172 A173 A196 Q259 S450 F451 G452 Y453 Q483 L484 E487 A489 T490 S491 2.1.1.13 0008705,0009086,0031419,0046872 Q5SKM5 37821448 1201 PLLERLKRRVVEGRKQGLEADLEEALKAGHKPLDLINGPLLAGMKEVGDLFGAGKMQLPFVLQAAEVMKRAVAYLEPHMEKEGKGTLVLATVKGDVHDIGKNLVDIILSNNGYRVVNLGIKVPIEEILKAVEAHKPHAVGMSGLLVKSTLVMKENLEYMRDRGYTLPVILGGAALTRSYVEELRAIYPNVYYAEDAFEGLRLMEELTGHAPPELTRRARPVGEAPAVPRPPFFGVRVEEGLDLATIAHYVNKLALYRGQWGYSRKGLSREAWQALVEREAEPVFQRLLKEAMAEGWLEPKVLYGFFPVAREGEELLVFSPETGEVLERFRFPRQKGGGLSLVDYFRPRFAAPLGDEADWMPKEAFRAGARDVLGVQLVTMGEAPSRKAQALFASGAYQDYLFVHGFSVEMTEALAEYWHKRMRQMWGIAHQDATEIQKLFQQGYQGARYSFGYPACPDLADQAKLDRLMGFHRVGVRLTENFQLEPEHATSALVVHHPEARYFSVD 8sse E 3.15 BS01 B12 E 1 H761 V768 M805 S806 L809 V810 I833 G835 G836 A837 A860 H1083 V1087 S1129 F1130 G1131 Y1132 Q1141 L1163 E1166 T1169 S1170 H97 V104 M141 S142 L145 V146 I169 G171 G172 A173 A196 H405 V409 S451 F452 G453 Y454 Q463 L485 E488 T491 S492 2.1.1.13 0008705,0009086,0031419,0046872 Q5SKM5 37821448 1201 PLLERLKRRVVEGRKQGLEADLEEALKAGHKPLDLINGPLLAGMKEVGDLFGAGKMQLPFVLQAAEVMKRAVAYLEPHMEKEGKGTLVLATVKGDVHDIGKNLVDIILSNNGYRVVNLGIKVPIEEILKAVEAHKPHAVGMSGLLVKSTLVMKENLEYMRDRGYTLPVILGGAALTRSYVEELRAIYPNVYYAEDAFEGLRLMEELTGHAPPELTRPRARPVGEAPAVPRPPFFGVRVEEGLDLATIAHYVNKLALYRGQWGYSRKGLSREAWQALVEREAEPVFQRLLKEAMAEGWLEPKVLYGFFPVAREGEELLVFSPETGEVLERFRFPRQKGGGLSLVDYFRPRFAAPLGDEADWMPKEAFRAGARDVLGVQLVTMGEAPSRKAQALFASGAYQDYLFVHGFSVEMTEALAEYWHKRMRQMWGIAHQDATEIQKLFQQGYQGARYSFGYPACPDLADQAKLDRLMGFHRVGVRLTENFQLEPEHATSALVVHHPEARYFSVD 8sse F 3.15 BS01 B12 F 1 H761 V768 M805 S806 L809 I833 G835 G836 A837 A860 V1087 S1129 F1130 G1131 Y1132 L1138 Q1162 L1163 E1166 A1168 S1170 H97 V104 M141 S142 L145 I169 G171 G172 A173 A196 V407 S449 F450 G451 Y452 L458 Q482 L483 E486 A488 S490 2.1.1.13 0008705,0009086,0031419,0046872 Q5SKM5 37821448 1201 PLLERLKRRVVEGRKQGLEADLEEALKAGHKPLDLINGPLLAGMKEVGDLFGAGKMQLPFVLQAAEVMKRAVAYLEPHMEKEGKGTLVLATVKGDVHDIGKNLVDIILSNNGYRVVNLGIKVPIEEILKAVEAHKPHAVGMSGLLVKSTLVMKENLEYMRDRGYTLPVILGGAALTRSYVEELRAIYPNVYYAEDAFEGLRLMEELTGHAPPELTRARPVGEAPAVPRPPFFGVRVEEGLDLATIAHYVNKLALYRGQWGYSRKGLSREAWQALVEREAEPVFQRLLKEAMAEGWLEPKVLYGFFPVAREGEELLVFSPETGEVLERFRFPRQKGGGLSLVDYFRPRFAAPLGDEADWMPKEAFRAGARDVLGVQLVTMGEAPSRKAQALFASGAYQDYLFVHGFSVEMTEALAEYWHKRMRQMWGIAHQDATEIQKLFQQGYQGARYSFGYPACPDLADQAKLDRLMGFHRVGVRLTENFQLEPEHATSALVVHHPEARYFSVD 8t0q A 3.06 BS01 B12 A 1 H133 V135 G136 I140 Y146 L185 S187 C220 G221 G222 P223 F239 G240 P241 T243 H122 V124 G125 I129 Y135 L174 S176 C209 G210 G211 P212 F228 G229 P230 T232 Q8RBT2 401 QYDTTLDLTRVKPYGDTMNDGKVQLSFTLPVPDGAKAVEAAKQLAKKMGLENPMVVYHAPLDKNFTFFIIYGSLIHTVDYTSIQVQELEIKAMSMEETNEYIKKHIGRKVVVVGATTGTDAHTVGLDAIMNMKGYAGHYGLERYEMIEAYNLGSQVPNEEFVKKAIEVGADALLVSQTVTQKDAHIKNLTHLVELLEAEGIRDKVLLICGGPRITHELAKELGYDAGFGPGTFADHVATFIVTEMVKRKIPGLKGYK 8t0q B 3.06 BS01 B12 B 1 A132 H133 V135 G136 I140 Y146 L185 S187 G221 G222 T243 A120 H121 V123 G124 I128 Y134 L173 S175 G209 G210 T231 Q8RBT2 401 YDTTLDLTRVKPYGDTMNDGKVQLSFTLPVPDGAKAVEAAKQLAKKMGLENPMVVYHAPLDKNFTFFIIYGSLIHTVDYTSIQVQELEIKAMSMEETNEYIKKHIGRKVVVVGATTGTDAHTVGLDAIMNMKGYAGHYGLERYEMIEAYNLGSQVPNEEFVKKAIEVGADALLVSQTVTQKDAHIKNLTHLVELLEAEGIRDKVLLICGGPRITHELAKELGYDAGFGPGTFADHVATFIVTEMVKRKIPGLKGYK 8t0v B 3.0 BS01 B12 B 1 D131 A132 H133 V135 G136 I140 L185 S187 V190 Q192 I219 C220 G221 R224 F239 P241 T243 D118 A119 H120 V122 G123 I127 L172 S174 V177 Q179 I206 C207 G208 R211 F226 P228 T230 Q8RBT2 301 DTTLDLTRVKPYGDTMNDGKVQLSFTLPVPDGAKAVEAAKQLAKKMGLENPMVVYHAPLDKNFTFFIIYGSLIHTVDYTSIQVQELEIKAMSMEETNEYIKKHIGRKVVVVGATTGTDAHTVGLDAIMNMKGYAGHYGLERYEMIEAYNLGSQVPNEEFVKKAIEVGADALLVSQTVTQKDAHIKNLTHLVELLEAEGIRDKVLLICGGPRITHELAKELGYDAGFGPGTFADHVATFIVTEMVKRKIPGLKGYK 8t0v D 3.0 BS01 B12 B 1 T187 G205 T376 E412 H415 T186 G204 T375 E411 H414 Q8RBT3 301 RESKLNLDWELVDKAREAARNIVKDTQKFIDAHTTVSVERTVCRLLGIDGVNDLGVPLPNVVVDHIKSKGNLSLGAATYIGNAMIYTGLSPQEIAERVAKGELDLTSIPMADLFEIKLAVQDIAIKTVEKIRENRRKREEFLKKYGDKEGPLLYVIVATGNIYEDVVQAQAAARQGADVIAVIRATAQSLLDYVPYGPTTEGFGGTYATQENFRIMRKALDEVSEELGRYIRLCNYASGLCMPEIAAMGALERLDVMLNDALYGILFRDINMKRTMVDQFFSRVINGFAGIIINTGEDNYLTTADAYEKAHTVLASQLINEQFALIAGIPEEQMGLGHAFEMNPDLRNGFLYELAQAQMVREIFPKAPLKYMPPTKYMTGNIFKGHVQDAMFNVVTIMTKQRIHLLGMLTEAIHTPFMSDRALSIESAKYIFNNMADIADEIYFKEGGIIQRRANEVLKKAYELLKEIEQEGLFKALEQGKFADIKRPIDGGKGLEGVVEKDPNYFNPFIDLMLRGD