12as A 2.2 BS02 AMP A 1 R100 L109 S111 V114 Q116 L249 S250 G296 R299 R97 L106 S108 V111 Q113 L246 S247 G293 R296 D46 R100 Q116 D235 E248 S251 D43 R97 Q113 D232 E245 S248 6.3.1.1 0004071,0005524,0005737,0005829,0006529,0006974,0016874,0042802,0042803,0070981 P00963 9437423 332 AYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGAEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLELEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQAGVWPAAVRESVPSLL 12as B 2.2 BS02 AMP B 1 R100 E103 S111 V114 Q116 E248 L249 S250 S251 G296 R299 R97 E100 S108 V111 Q113 E245 L246 S247 S248 G293 R296 D46 R100 Q116 D235 E248 S251 D43 R97 Q113 D232 E245 S248 6.3.1.1 0004071,0005524,0005737,0005829,0006529,0006974,0016874,0042802,0042803,0070981 P00963 9437423 332 AYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGAEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLELEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQAGVWPAAVRESVPSLL 1aer B 2.3 BS02 AMP B 1 H440 T442 A446 I450 R456 R458 F469 H41 T43 A47 I51 R57 R59 F70 E553 E148 2.4.2.36 0047286 P11439 8692916 701 FLGDGGDVSFSTRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRARSQDLDAIWRGFYIAGDPALAYGYAQDQEPDRGRIRNGALLRVYVPRSSLPGFYRTSLTLAAPEAAGEVERLIGHPLPLRLDAITGPRLETILGWPLAERTVVIPSAIPTDPRNVGGDLDPSSIPDKEQAISALPDY 1amu A 1.9 BS02 AMP A 1 T190 G302 S303 A304 A322 Y323 T326 D413 Y425 K517 T174 G281 S282 A283 A301 Y302 T305 D392 Y404 K496 T190 L210 T326 E327 K434 R439 K517 T174 L189 T305 E306 K413 R418 K496 5.1.1.11 P0C061 9250661 567 GTHEEEQYLFAVNNTKAEYPRDKTIHQLFEEQVSKRPNNVAIVCENEQLTYHELNVKANQLARIFIEKGIGKDTLVGIMMEKSIDLFIGILAVLKAGGAYVPIDIEYPKERIQYILDDSQARMLLTQKHLVHLIHNIQFNGQVEIFEEDTIKIREGTNLHVPSKSTDLAYVIYTSPKGTMLEHKGISNLKVFFENSLNVTEKDRIGQFASISFDASVWEMFMALLTGASLYIILKDTINDFVKFEQYINQKEITVITLPPTYVVHLDPERILSIQTLITAGSATSPSLVNKWKEKVTYINAYGPTETTICATTWVATKETIGHSVPIGAPIQNTQIYIVDENLQLKSVGEAGELCIGGEGLARGYWKRPELTSQKFVDNPFVPGEKLYKTGDQARWLSDGNIEYLGRIDNQVKIRGHRVELEEVESILLKHMYISETAVSVHKDHQEQPYLCAYFVSEKHIPLEQLRQFSSEELPTYMIPSYFIQLDKMPLTSNGKIDRKQLPEPDLTF 1amu B 1.9 BS03 AMP B 1 T190 G302 S303 A304 A322 Y323 T326 D413 Y425 K517 T173 G280 S281 A282 A300 Y301 T304 D391 Y403 K495 T190 L210 T326 E327 K434 R439 K517 T173 L188 T304 E305 K412 R417 K495 5.1.1.11 P0C061 9250661 567 GTHEEEQYLFAVNNTKAEYPRDKTIHQLFEEQVSKRPNNVAIVCENEQLTYHELNVKANQLARIFIEKGIGKDTLVGIMMEKSIDLFIGILAVLKAGGAYVPIDIEYPKERIQYILDDSQARMLLTQKHLVHLIHNQFNGQVEIFEEDTIKIREGTNLHVPSKSTDLAYVIYTNPKGTMLEHKGISNLKVFFENSLNVTEKDRIGQFASISFDASVWEMFMALLTGASLYIILKDTINDFVKFEQYINQKEITVITLPPTYVVHLDPERILSIQTLITAGSATSPSLVNKWKEKVTYINAYGPTETTICATTWVATKETIGHSVPIGAPIQNTQIYIVDENLQLKSVGEAGELCIGGEGLARGYWKRPELTSQKFVDNPFVPGEKLYKTGDQARWLSDGNIEYLGRIDNQVKIRGHRVELEEVESILLKHMYISETAVSVHKDHQEQPYLCAYFVSEKHIPLEQLRQFSSEELPTYMIPSYFIQLDKMPLTSNGKIDRKQLPEPDLTF 1ank A 2.0 BS01 AMP A 1 T31 L35 R36 K57 L58 V59 V64 R88 Q92 R156 T31 L35 R36 K57 L58 V59 V64 R88 Q92 R156 K13 R88 R123 R156 R167 K13 R88 R123 R156 R167 2.7.4.3 0000287,0004017,0004550,0005515,0005524,0005737,0005829,0006139,0006172,0009123,0009132,0009165,0015951,0016208,0016301,0016310,0016776,0019205,0044209,0046940,0050145 P69441 7937733 215 MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG 1ank B 2.0 BS01 AMP B 1 T31 L35 R36 M53 L58 V59 V64 G85 R88 Q92 R156 T31 L35 R36 M53 L58 V59 V64 G85 R88 Q92 R156 K13 R88 R123 R156 R167 K13 R88 R123 R156 R167 2.7.4.3 0000287,0004017,0004550,0005515,0005524,0005737,0005829,0006139,0006172,0009123,0009132,0009165,0015951,0016208,0016301,0016310,0016776,0019205,0044209,0046940,0050145 P69441 7937733 215 MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG 1c0a A 2.4 BS02 AMP A 1 F304 V306 K347 G348 A350 F304 V306 K347 G348 A350 E482 G485 R537 E482 G485 R537 6.1.1.12 0000166,0003676,0004812,0004815,0005524,0005737,0005829,0006412,0006418,0006422,0016874 P21889 10562565 800 MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEDILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVK 1cja A 2.9 BS01 AMP A 1 K80 T82 L85 I96 M162 V165 I231 D232 K64 T66 L69 I80 M146 V149 I215 D216 2.7.11.1 P80197 10357805 425 AGALWEIEKELFTKLPAPSSAINSHLQPAKPFKVDLSTAVSYNDIGDINWKNLQQFKGIERSEKGTEGLFFVETESGVFIVKRSTNIESETFCSLLCMRLGLHAPKVRVVSSNSEEGTNMLECLAAIDKSFRVITTLANQANILLMELVRGITLNKLTTTSAPEVLTKSTMQQLGSLMALDVIVNNSDRLPIAWTNEGNLDNIMLSERGATVVPIDSKIIPLDASHPHGERVRELLRTLIAHPGHESSQFHSIRDIITLYTGYDVGTEGSISMQEGFLATVRECASFDLDAFERELLSWQESLQKCHNLSISPQAIPFILRMLRIFH 1cja B 2.9 BS01 AMP B 1 K80 G81 T82 I96 M162 V165 I231 D232 K64 G65 T66 I80 M146 V149 I215 D216 2.7.11.1 P80197 10357805 525 AGALWEIEKELFTKLPAPSSAINSHLQPAKPFKVDLSTAVSYNDIGDINWKNLQQFKGIERSEKGTEGLFFVETESGVFIVKRSTNIESETFCSLLCMRLGLHAPKVRVVSSNSEEGTNMLECLAAIDKSFRVITTLANQANILLMELVRGITLNKLTTTSAPEVLTKSTMQQLGSLMALDVIVNNSDRLPIAWTNEGNLDNIMLSERGATVVPIDSKIIPLDASHPHGERVRELLRTLIAHPGHESSQFHSIRDIITLYTGYDVGTEGSISMQEGFLATVRECASFDLDAFERELLSWQESLQKCHNLSISPQAIPFILRMLRIFH 1ct9 A 2.0 BS01 AMP A 1 L232 L233 S234 S239 A271 V272 D279 M332 S346 G347 E348 L232 L233 S234 S239 A255 V256 D263 M316 S330 G331 E332 A1 L50 N74 G75 T321 R324 E348 M382 A1 L50 N74 G75 T305 R308 E332 M366 6.3.5.4 0004066,0004071,0005524,0005737,0005829,0006529,0006541,0008652,0009063,0016597,0016874,0042802,0042803,0070981 P22106 10587437 1100 ASIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNAILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEVILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVASEMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALEDSVKSHLMSDVPYGVLLSGGLDSSIISAITKKYALHSFAVGLPGSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMSRKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKAMSAWGVEARVPFLDKKFLDVAMRINPQDKMCKMEKHILRECFEAYLPASVAWRQKEQFSDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPLPSAAECVPG 1ct9 B 2.0 BS01 AMP B 1 L232 L233 S234 D238 S239 A271 V272 M332 S346 G347 E348 D351 L232 L233 S234 D238 S239 A258 V259 M319 S333 G334 E335 D338 A1 L50 N74 G75 T321 R324 E348 M382 A1 L50 N74 G75 T308 R311 E335 M369 6.3.5.4 0004066,0004071,0005524,0005737,0005829,0006529,0006541,0008652,0009063,0016597,0016874,0042802,0042803,0070981 P22106 10587437 1107 ASIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNAILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEVILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVASEMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALEDSVKSHLMSDVPYGVLLSGGLDSSIISAITKKYAWPQLHSFAVGLPGSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMSRKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKAMSAWGVEARVPFLDKKFLDVAMRINPQDKMCKMEKHILRECFEAYLPASVAWRQDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPLPSAAECVPG 1ct9 C 2.0 BS01 AMP C 1 L233 S234 S239 F270 A271 V272 M332 S346 G347 E348 D384 L233 S234 S239 F257 A258 V259 M319 S333 G334 E335 D371 A1 L50 N74 G75 T321 R324 E348 M382 A1 L50 N74 G75 T308 R311 E335 M369 6.3.5.4 0004066,0004071,0005524,0005737,0005829,0006529,0006541,0008652,0009063,0016597,0016874,0042802,0042803,0070981 P22106 10587437 1114 ASIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNAILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEVILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVASEMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALEDSVKSHLMSDVPYGVLLSGGLDSSIISAITKKYAWPQLHSFAVGLPGSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMSRKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKAMSAWGVEARVPFLDKKFLDVAMRINPQDKMCKMEKHILRECFEAYLPASVAWRQDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPLPSAAECVPG 1ct9 D 2.0 BS01 AMP D 1 L232 L233 S234 S239 F270 A271 V272 M332 S346 G347 E348 L232 L233 S234 S239 F256 A257 V258 M318 S332 G333 E334 A1 L50 N74 G75 T321 R324 E348 M382 A1 L50 N74 G75 T307 R310 E334 M368 6.3.5.4 0004066,0004071,0005524,0005737,0005829,0006529,0006541,0008652,0009063,0016597,0016874,0042802,0042803,0070981 P22106 10587437 1121 ASIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNAILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEVILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVASEMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALEDSVKSHLMSDVPYGVLLSGGLDSSIISAITKKYAAQLHSFAVGLPGSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMSRKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKAMSAWGVEARVPFLDKKFLDVAMRINPQDKMCGKMEKHILRECFEAYLPASVAWRQDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPLPSAAECVPG 1del B 2.2 BS03 AMP B 1 R11 G13 D15 T16 N223 G225 S226 L227 R11 G13 D15 T16 N213 G215 S216 L217 D15 R68 D15 R68 2.7.4.13 0005524,0016301,0016310,0047507 P04531 8670851 302 MKLIFLSGVKRSGKDTTADFIMSNYSAVKYQLAGPIKDALAYAWGVFAANTDYPCLTRKEFEGIDYDRETNLNLTKLEVITIMEQAFCYLNGKSPIKGVFVFDDEGKESVNFVAFNKITDVINNIEDQWSVRRLMQALGTDLIVNNFDRMYWVKLFALDYLDKFNSGYDYYIVPDTRQDHEMDAARAMGATVIHVVRPGAGLPIRDGDLVITNDGSLEELFSKIKNTLKVL 1dgs A 2.9 BS02 AMP A 1 E114 K116 E169 Y221 H253 K288 K312 E114 K116 E169 Y221 H253 K288 K312 E114 K116 D118 Y221 K312 C406 C409 C422 C427 E114 K116 D118 Y221 K312 C406 C409 C422 C427 6.5.1.2 0003677,0003911,0006260,0006281 Q9ZHI0 10698952 700 MTREEARRRINELRDLIRYHNYRYYVLADPEISDAEYDRLLRELKELEERFPEFKSPDSPTEQVGARPLEPTFRPVRHPTRMYSLDNAFTYEEVLAFEERLEREAEAPSLYTVEHKVDGLSVLYYEEGVWSTGSGDGEVGEEVTQNLLTIPTIPRRLKGVPDRLEVRGEVYMPIEAFLRLNEELEERGEKVFKNPRNAAAGSLRQKDPRVTAKRGLRATFYALGLGLGLEESGLKSQYELLLWLKEKGFPVEHCYEKALGAEGVEEVYRRGLAQRHALPFEADGVVLKLDDLTLWGELGYTARAPRFALAYKFPAEEKETRLLDVVFQVGRTGRVTPVGVLEPVFIEGSEVSRVTLHNESYIEELDIRIGDWVLVHKAGGVIPEVLRVLKERRTGKERPIRWPEACPECGHRLVKEGKVHRCPNPLCPAKRFEAIRHYASRKAMDIEGLGEKLIERLLEKGLVRDVADLYHLRKEDLLGLERMGEKSAQNLLRQIEESKHRGLERLLYALGLPGVGEVLARNLARRFGTMDRLLEASLEELIEVEEVGELTARAILETLKDPAFRDLVRRLKEAGVSMESK 1dgs B 2.9 BS02 AMP B 1 E2114 K2116 V2117 L2120 E2169 Y2221 K2312 E114 K116 V117 L120 E169 Y221 K312 E2114 K2116 D2118 Y2221 K2312 C2406 C2409 C2422 C2427 E114 K116 D118 Y221 K312 C406 C409 C422 C427 6.5.1.2 0003677,0003911,0006260,0006281 Q9ZHI0 10698952 2700 MTREEARRRINELRDLIRYHNYRYYVLADPEISDAEYDRLLRELKELEERFPEFKSPDSPTEQVGARPLEPTFRPVRHPTRMYSLDNAFTYEEVLAFEERLEREAEAPSLYTVEHKVDGLSVLYYEEGVWSTGSGDGEVGEEVTQNLLTIPTIPRRLKGVPDRLEVRGEVYMPIEAFLRLNEELEERGEKVFKNPRNAAAGSLRQKDPRVTAKRGLRATFYALGLGLGLEESGLKSQYELLLWLKEKGFPVEHCYEKALGAEGVEEVYRRGLAQRHALPFEADGVVLKLDDLTLWGELGYTARAPRFALAYKFPAEEKETRLLDVVFQVGRTGRVTPVGVLEPVFIEGSEVSRVTLHNESYIEELDIRIGDWVLVHKAGGVIPEVLRVLKERRTGKERPIRWPEACPECGHRLVKEGKVHRCPNPLCPAKRFEAIRHYASRKAMDIEGLGEKLIERLLEKGLVRDVADLYHLRKEDLLGLERMGEKSAQNLLRQIEESKHRGLERLLYALGLPGVGEVLARNLARRFGTMDRLLEASLEELIEVEEVGELTARAILETLKDPAFRDLVRRLKEAGVSMESK 1dma B 2.5 BS02 AMP B 1 H440 T442 A446 S449 I450 R456 R458 F469 H41 T43 A47 S50 I51 R57 R59 F70 E553 E145 2.4.2.36 0047286 P11439 7568123 701 FLGDGGDVSFSTRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRARSQDLDAIWRGFYIAGDPALAYGYAQIRNGALLRVYVPRSSLPGFYRTSLTLAAPEAAGEVERLIGHPLPLRLDAITGPEEEGGRLETILGWPLAERTVVIPSAIPTDPRNVDLDPSSIPDKEQAISALPD 1ds5 A 3.16 BS03 AMP A 1 I66 H160 N161 M163 I174 I61 H155 N156 M158 I169 D156 K158 N161 D175 S194 D151 K153 N156 D170 S189 2.7.11.1 0004672,0004674,0005524,0005634,0005829,0005956,0006338,0006468,0016310,0043231,0044024,0051726,0106310 P28523 10931203 501 MSKARVYADVNVLRPKEYWDYEALTVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEKCIIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYVNNTDFKVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDGLNVYLNKYRIELDPQLEALVGRHSRKPWLKFMNADNQHLVSPEAIDFLDKLLRYDHQERLTALEAMTHPYFQQVRAAENS 1ds5 B 3.16 BS04 AMP B 1 S51 V53 I66 K68 V116 M163 D175 S46 V48 I61 K63 V111 M158 D170 D156 K158 N161 D175 S194 D151 K153 N156 D170 S189 2.7.11.1 0004672,0004674,0005524,0005634,0005829,0005956,0006338,0006468,0016310,0043231,0044024,0051726,0106310 P28523 10931203 801 MSKARVYADVNVLRPKEYWDYEALTVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEKCIIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYVNNTDFKVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDGLNVYLNKYRIELDPQLEALVGRHSRKPWLKFMNADNQHLVSPEAIDFLDKLLRYDHQERLTALEAMTHPYFQQVRAAENS 1ds5 C 3.16 BS03 AMP C 1 I66 V116 M163 D175 I61 V111 M158 D170 D156 K158 N161 D175 S194 D151 K153 N156 D170 S189 2.7.11.1 0004672,0004674,0005524,0005634,0005829,0005956,0006338,0006468,0016310,0043231,0044024,0051726,0106310 P28523 10931203 601 MSKARVYADVNVLRPKEYWDYEALTVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEKCIIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYVNNTDFKVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDGLNVYLNKYRIELDPQLEALVGRHSRKPWLKFMNADNQHLVSPEAIDFLDKLLRYDHQERLTALEAMTHPYFQQVRAAENS 1ds5 D 3.16 BS03 AMP D 1 I66 K68 V116 M163 D175 I61 K63 V111 M158 D170 D156 K158 N161 D175 S194 D151 K153 N156 D170 S189 2.7.11.1 0004672,0004674,0005524,0005634,0005829,0005956,0006338,0006468,0016310,0043231,0044024,0051726,0106310 P28523 10931203 701 MSKARVYADVNVLRPKEYWDYEALTVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEKCIIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYVNNTDFKVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDGLNVYLNKYRIELDPQLEALVGRHSRKPWLKFMNADNQHLVSPEAIDFLDKLLRYDHQERLTALEAMTHPYFQQVRAAENS 1ecj A 2.5 BS01 AMP A 1 Y74 D366 D367 S368 V370 R371 G372 T374 Y74 D366 D367 S368 V370 R371 G372 T374 C1 G27 N101 G102 Y258 R321 K326 M336 D444 C1 G27 N101 G102 Y258 R321 K326 M336 D444 2.4.2.14 0000287,0004044,0005737,0005829,0006164,0006189,0006541,0009113,0016757,0042802,0046872,0097216 P0AG16 9514258 505 CGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFRLRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHNGNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAATNRLIRGAYACVAMIIGHGMVAFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLGFDFLRDVAPGEAIYITEEGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSARVNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRTFIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVYLASAAPEIRFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIDAVRAENPDIQQFECSVFNGVYVTKDVDQGYLDFLDTLRNDDAKAVQRQ 1ecj C 2.5 BS01 AMP C 1 Y74 Y258 D366 D367 S368 V370 R371 G372 T374 Y74 Y258 D366 D367 S368 V370 R371 G372 T374 C1 G27 N101 G102 Y258 R321 K326 M336 D444 C1 G27 N101 G102 Y258 R321 K326 M336 D444 2.4.2.14 0000287,0004044,0005737,0005829,0006164,0006189,0006541,0009113,0016757,0042802,0046872,0097216 P0AG16 9514258 505 CGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFRLRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHNGNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAATNRLIRGAYACVAMIIGHGMVAFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLGFDFLRDVAPGEAIYITEEGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSARVNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRTFIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVYLASAAPEIRFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIDAVRAENPDIQQFECSVFNGVYVTKDVDQGYLDFLDTLRNDDAKAVQRQ 1efp B 2.6 BS02 AMP A 1 P6 V7 D39 I63 V101 A119 G120 Q122 A123 N126 M128 N129 T131 P6 V7 D39 I63 V101 A119 G120 Q122 A123 N126 M128 N129 T131 ? 0009055 P38975 10026281 400 MKVLVPVKRLIDYNVKARVKSDGSGVDLANVKMSMNPFDEIAVEEAIRLKEKGQAEEIIAVSIGVKQAAETLRTALAMGADRAILVVAADDVQQDIEPLAVAKILAAVARAEGTELIIAGKQAIDNDMNATGQMLAAILGWAQATFASKVEIEGAKAKVTREVDGGLQTIAVSLPAVVTADLRLNEPRYASLPNIMKAKKKPLDEKTAADYGVDVAPRLEVVSVREPEGRKAGIKVGSVDELVGKL 1efp D 2.6 BS02 AMP C 1 P6 V7 D39 I63 A119 G120 Q122 A123 N126 M128 N129 T131 P6 V7 D39 I63 A119 G120 Q122 A123 N126 M128 N129 T131 ? 0009055 P38975 10026281 400 MKVLVPVKRLIDYNVKARVKSDGSGVDLANVKMSMNPFDEIAVEEAIRLKEKGQAEEIIAVSIGVKQAAETLRTALAMGADRAILVVAADDVQQDIEPLAVAKILAAVARAEGTELIIAGKQAIDNDMNATGQMLAAILGWAQATFASKVEIEGAKAKVTREVDGGLQTIAVSLPAVVTADLRLNEPRYASLPNIMKAKKKPLDEKTAADYGVDVAPRLEVVSVREPEGRKAGIKVGSVDELVGKL 1efv B 2.1 BS01 AMP B 1 A9 V10 K11 C42 C66 V104 L122 G123 Q125 A126 D129 C131 N132 T134 A6 V7 K8 C39 C63 V101 L119 G120 Q122 A123 D126 C128 N129 T131 ? 0005515,0005739,0005759,0009055,0009063,0022904,0033539,0045251 P38117 8962055 600 LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTEDLVAKLKEIGRI 1eyj A 2.28 BS04 AMP A 1 E20 G21 A24 G26 T27 E29 M30 K112 Y113 M177 E12 G13 A16 G18 T19 E21 M22 K104 Y105 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 10913263 341 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1eyj B 2.28 BS04 AMP B 1 E20 G21 A24 T27 G28 E29 M30 K112 Y113 R140 V160 M177 E12 G13 A16 T19 G20 E21 M22 K104 Y105 R132 V152 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 10913263 342 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1eyk A 2.23 BS04 AMP A 1 V17 E20 G21 T27 E29 M30 K112 Y113 R140 V160 V9 E12 G13 T19 E21 M22 K104 Y105 R132 V152 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 10913263 341 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1eyk B 2.23 BS04 AMP B 1 E20 G21 G26 T27 G28 E29 M30 K112 Y113 R140 M177 E12 G13 G18 T19 G20 E21 M22 K104 Y105 R132 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 10913263 342 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fa9 A 2.4 BS02 AMP A 1 W67 Q71 Y75 R309 R310 W63 Q67 Y71 R305 R306 H377 K568 R569 K574 T676 K680 H373 K564 R565 K570 T672 K676 2.4.1.1 0000166,0002060,0004645,0005515,0005524,0005536,0005576,0005737,0005829,0005975,0005977,0005980,0006015,0008184,0009617,0016208,0016757,0019842,0030170,0030246,0032052,0034774,0042593,0042802,0070062,0070266,0102250,0102499,1904813 P06737 10949035 997 TDQEKRRQISIRGIVGVENVAELKKSFNRHLHFTLVKDRNVATTRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDIEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYGNPWEKSRPEFMLPVHFYGKVEHTNTGTKWIDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKASKFGSTRGAGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWELTQKTFAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVALFPKDVDRLRRMSLIEEEGSKRINMAHLCIVGSHAVNGVAKIHSDIVKTKVFKDFSELEPDKFQNKTNGITPRRWLLLCNPGLAELIAEKIGEDYVKDLSQLTKLHSFLGDDVFLRELAKVKQENKLKFSQFLETEYKVKINPSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIKKDPKKLFVPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRIDDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPKQPDLFKDIINMLFYHDRFKVFADYEAYVKCQDKVSQLYMNPKAWNTMVLKNIAASGKFSSDRTIKEYAQNIWNVEPSDLKISLSN 1fbp A 2.5 BS03 AMP A 1 G21 T27 E29 M30 K112 Y113 R140 M177 G16 T22 E24 M25 K93 Y94 R121 M158 D68 D74 E97 E98 D118 L120 D121 E280 D49 D55 E78 E79 D99 L101 D102 E261 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 2164670 337 FDTNIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIDQVKKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fbp B 2.5 BS03 AMP B 1 V17 Q20 G21 G26 T27 G28 E29 M30 T31 K112 Y113 M177 V12 Q15 G16 G21 T22 G23 E24 M25 T26 K93 Y94 M158 D68 D74 E97 E98 D118 L120 D121 E280 D49 D55 E78 E79 D99 L101 D102 E261 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 2164670 337 FDTNIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIDQVKKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fj9 A 2.5 BS05 AMP A 1 E20 G21 T27 E29 M30 K112 Y113 R140 M177 E12 G13 T19 E21 M22 K96 Y97 R124 M161 D74 E97 E98 D118 L120 D121 E280 D58 E81 E82 D102 L104 D105 E264 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 10998248 401 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLWGIAGSKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fj9 B 2.5 BS05 AMP B 1 E20 G21 A24 G26 T27 E29 M30 K112 Y113 M177 E12 G13 A16 G18 T19 E21 M22 K96 Y97 M161 D74 E97 E98 D118 L120 D121 E280 D58 E81 E82 D102 L104 D105 E264 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 10998248 411 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLWGIAGSKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpd A 2.1 BS04 AMP A 1 V17 Q20 G21 G26 T27 E29 M30 K112 Y113 M177 V9 Q12 G13 G18 T19 E21 M22 K94 Y95 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7703244 339 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpd B 2.1 BS04 AMP B 1 Q20 G21 A24 G26 T27 E29 M30 K112 Y113 R140 M177 Q12 G13 A16 G18 T19 E21 M22 K94 Y95 R122 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7703244 339 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpe A 2.2 BS04 AMP A 1 V17 Q20 G21 G26 T27 E29 M30 Y113 V160 V9 Q12 G13 G18 T19 E21 M22 Y95 V142 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7703244 339 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpe B 2.2 BS04 AMP B 1 Q20 G21 A24 G26 T27 E29 M30 K112 Y113 R140 M177 Q12 G13 A16 G18 T19 E21 M22 K94 Y95 R122 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7703244 339 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpf A 2.1 BS04 AMP A 1 Q20 G21 G26 T27 E29 M30 Y113 M177 Q12 G13 G18 T19 E21 M22 Y95 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7703244 339 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpf B 2.1 BS04 AMP B 1 Q20 G21 G26 T27 E29 M30 K112 Y113 R140 M177 Q12 G13 G18 T19 E21 M22 K94 Y95 R122 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7703244 339 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpg A 2.3 BS04 AMP A 1 V17 Q20 G21 G26 T27 E29 M30 K112 Y113 M177 V9 Q12 G13 G18 T19 E21 M22 K94 Y95 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7703244 339 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpg B 2.3 BS04 AMP B 1 Q20 G21 A24 G26 T27 E29 M30 K112 Y113 R140 M177 Q12 G13 A16 G18 T19 E21 M22 K94 Y95 R122 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7703244 339 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpi A 2.3 BS04 AMP A 1 V17 Q20 G21 G26 T27 E29 M30 Y113 R140 V9 Q12 G13 G18 T19 E21 M22 Y95 R122 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 -logKd/Ki=5.89, IC50=1.3uM IC50=1300nM P00636 7568043 339 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpi B 2.3 BS04 AMP B 1 Q20 G21 A24 G26 T27 E29 M30 Y113 R140 Q12 G13 A16 G18 T19 E21 M22 Y95 R122 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7568043 339 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpj A 2.2 BS02 AMP A 1 V17 Q20 G21 G26 T27 E29 M30 Y113 M177 V9 Q12 G13 G18 T19 E21 M22 Y95 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7568043 338 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpj B 2.2 BS02 AMP B 1 V17 Q20 G21 A24 T27 E29 M30 K112 Y113 R140 V9 Q12 G13 A16 T19 E21 M22 K94 Y95 R122 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7568043 338 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpl A 2.3 BS04 AMP A 1 V17 Q20 G21 G26 T27 E29 M30 K112 Y113 R140 V9 Q12 G13 G18 T19 E21 M22 K94 Y95 R122 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7568043 339 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fpl B 2.3 BS04 AMP B 1 Q20 G21 A24 G26 T27 E29 M30 K112 Y113 R140 Q12 G13 A16 G18 T19 E21 M22 K94 Y95 R122 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7568043 339 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1frp A 2.0 BS03 AMP A 1 Q20 G21 A24 G26 T27 G28 E29 M30 K112 Y113 R140 M177 Q12 G13 A16 G18 T19 G20 E21 M22 K97 Y98 R125 M162 D74 E97 E98 D118 L120 D121 E280 D59 E82 E83 D103 L105 D106 E265 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7809062 338 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGAVKKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1frp B 2.0 BS03 AMP B 1 V17 Q20 G21 A24 G26 T27 G28 E29 M30 K112 Y113 R140 V9 Q12 G13 A16 G18 T19 G20 E21 M22 K97 Y98 R125 D74 E97 E98 D118 L120 D121 E280 D59 E82 E83 D103 L105 D106 E265 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 7809062 338 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGAVKKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1fsa A 2.3 BS03 AMP A 1 G21 G26 T27 G28 E29 K112 Y113 R140 G21 G26 T27 G28 E29 K112 Y113 R140 D68 D74 E97 E98 D118 L120 D121 E280 D68 D74 E97 E98 D118 L120 D121 E280 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 8931152 340 TDQAAFDTNIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVAAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK 1fsa B 2.3 BS03 AMP B 1 G21 A24 T27 G28 E29 M30 K112 Y113 R140 M177 G21 A24 T27 G28 E29 M30 K112 Y113 R140 M177 D68 D74 E97 E98 D118 L120 D121 E280 D68 D74 E97 E98 D118 L120 D121 E280 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 8931152 340 TDQAAFDTNIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVAAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK 1fta A 2.3 BS01 AMP A 1 V17 E20 G21 A24 G26 T27 G28 E29 L30 T31 K112 Y113 V9 E12 G13 A16 G18 T19 G20 E21 L22 T23 K96 Y97 D74 E97 E98 D118 L120 D121 E280 D58 E81 E82 D102 L104 D105 E264 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 -logKd/Ki=6.36, IC50=0.44uM IC50=3200nM P09467 7961695 338 DVVTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEAYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPIILGSPDDVLEFLKVYEKHS 1fta B 2.3 BS01 AMP B 1 G21 A24 G26 T27 E29 L30 Y113 R140 M177 G13 A16 G18 T19 E21 L22 Y95 R122 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 IC50=3200nM P09467 7961695 338 DVVTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEAYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPIILGSPDDVLEFLKVYEKHS 1fta C 2.3 BS01 AMP C 1 V17 E20 G21 A24 G26 T27 G28 E29 L30 K112 Y113 R140 M177 V9 E12 G13 A16 G18 T19 G20 E21 L22 K94 Y95 R122 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 -logKd/Ki=6.36, IC50=0.44uM IC50=3200nM P09467 7961695 338 DVVTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEAYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPIILGSPDDVLEFLKVYEKHS 1fta D 2.3 BS01 AMP D 1 E20 G21 A24 G26 T27 G28 E29 L30 T31 K112 Y113 M177 E12 G13 A16 G18 T19 G20 E21 L22 T23 K95 Y96 M160 D74 E97 E98 D118 L120 D121 E280 D57 E80 E81 D101 L103 D104 E263 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 IC50=3200nM P09467 7961695 338 DVVTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEAYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPIILGSPDDVLEFLKVYEKHS 1fvi A 2.0 BS01 AMP A 1 T25 P26 K27 I28 E67 F98 M164 K186 T24 P25 K26 I27 E66 F93 M159 K181 6.5.1.- 0000166,0003909,0003910,0005524,0006260,0006281,0006310 A7RCB1 11106756 501 AITKPLLAATLENIEDVQFPCLATPKIAGIRSVKQTQMLSRTFKPIRNSVMNRLLTELLPEGSDGEISIEGATFQDTTSAVMTGHAKFSYYWFDYVTDDPLKKYIDRVEDMKNYITVHPHILEHAQVKIIPLIPVEINNITELLQYERDVLSKGFEGVMIRKPDGKYKFGRSTLKEGILLKMKQFKDAEATIISMTALFKSGKVEEDVMGSIEVDYDGVVFSIGTGFDADQRRDFWQNKESYIGKMVKFKYFEMPRFPVFIGIR 1fyd A 2.25 BS01 AMP A 1 G44 I45 S46 S51 R78 L79 Q84 T157 G44 I45 S46 S51 R78 L79 Q84 T157 D50 E162 D50 E162 6.3.1.5 0003952,0004359,0005524,0005737,0008795,0009435,0016874,0030435,0046872 P08164 11375500 4000 SMQEKIMRELHVKPSIDPKQEIEDRVNFLKQYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVESIREEGGDAQFIAVRLPHGTQQDEDDAQLALKFIKPDKSWKFDIKSTVSAFSDQYQQETGDQLTDFNKGNVKARTRMIAQYAIGGQEGLLVLGTDHAAEAVTGFFTKYGDGGADLLPLTGLTKRQGRTLLKELGAPERLYLKEPTADLLDEKPQQSDETELGISYDEIDDYLEGKEVSAKVSEALEKRYSMTEHKRQVPASMFDDWWK 1g51 B 2.4 BS02 AMP B 1 V1313 Q1347 G1348 L1349 A1350 V1389 A1390 V313 Q347 G348 L349 A350 V389 A390 R1223 E1225 R1231 Q1232 E1476 G1479 R1531 R223 E225 R231 Q232 E476 G479 R531 6.1.1.12 0000166,0003676,0004812,0004815,0005524,0005737,0006412,0006418,0006422,0016874 P36419 7966328 800 MRRTHYAGSLRETHVGEEVVLEGWVNRRRDLGGLIFLDLRDREGLVQLVAHPASPAYATAERVRPEWVVRAKGLVRLRPEPNPRLATGRVEVELSALEVLAEAKTPPFPVDAGWRGEEEKEASEELRLKYRYLDLRRRRMQENLRLRHRVIKAIWDFLDREGFVQVETPFLTKSTPEGARDFLVPYRHEPGLFYALPQSPQLFKQMLMVAGLDRYFQIARCFRDEDLRADRQPDFTQLDLEMSFVEVEDVLELNERLMAHVFREALGVELPLPFPRLSYEEAMERYGSDKPDLRFGLELKEVGPLFRQSGFRVFQEAESVKALALPKALSRKEVAELEEVAKRHKAQGLAWARVEEGGFSGGVAKFLEPVREALLQATEARPGDTLLFVAGPRKVAATALGAVRLRAADLLGLKREGFRFLWVVDFPLLEWDEEEEAWTYMHHPFTSPHPEDLPLLEKDPGRVRALAYDLVLNGVEVGGGSIRIHDPRLQARVFRLLGIGEEEQREKFGFFLEALEYGAPPHGGIAWGLDRLLALMTGSPSIREVIAFPKNKEGKDPLTGAPSPVPEEQLRELGLMVVRP 1gph 1 3.0 BS02 AMP 1 1 Y242 S283 D345 D346 S347 V349 R350 T353 T388 Y242 S283 D345 D346 S347 V349 R350 T353 T388 E300 K305 Q315 K423 E300 K305 Q315 K423 2.4.2.14 0000287,0004044,0006164,0006189,0006541,0009113,0016757,0046872,0051536,0051539 P00497 8197456 467 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVDEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYPTEIYQDTVLPHVKEAVLTK 1gph 1 3.0 BS03 AMP 1 2 Y242 S244 R245 P246 D282 S283 K305 Y242 S244 R245 P246 D282 S283 K305 E300 K305 Q315 K423 E300 K305 Q315 K423 2.4.2.14 0000287,0004044,0006164,0006189,0006541,0009113,0016757,0046872,0051536,0051539 P00497 8197456 468 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVDEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYPTEIYQDTVLPHVKEAVLTK 1gph 1 3.0 BS04 AMP 2 2 I304 R307 I304 R307 E300 K305 Q315 K423 E300 K305 Q315 K423 2.4.2.14 0000287,0004044,0006164,0006189,0006541,0009113,0016757,0046872,0051536,0051539 P00497 8197456 468 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVDEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYPTEIYQDTVLPHVKEAVLTK 1gph 2 3.0 BS01 AMP 1 2 I304 R307 I304 R307 E300 K305 Q315 K423 E300 K305 Q315 K423 2.4.2.14 0000287,0004044,0006164,0006189,0006541,0009113,0016757,0046872,0051536,0051539 P00497 8197456 468 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVDEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYPTEIYQDTVLPHVKEAVLTK 1gph 2 3.0 BS03 AMP 2 1 Y242 S283 D345 D346 S347 V349 R350 G351 T352 T353 Y242 S283 D345 D346 S347 V349 R350 G351 T352 T353 E300 K305 Q315 K423 E300 K305 Q315 K423 2.4.2.14 0000287,0004044,0006164,0006189,0006541,0009113,0016757,0046872,0051536,0051539 P00497 8197456 467 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVDEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYPTEIYQDTVLPHVKEAVLTK 1gph 2 3.0 BS04 AMP 2 2 Y242 S244 R245 D282 S283 K305 Y242 S244 R245 D282 S283 K305 E300 K305 Q315 K423 E300 K305 Q315 K423 2.4.2.14 0000287,0004044,0006164,0006189,0006541,0009113,0016757,0046872,0051536,0051539 P00497 8197456 468 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVDEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYPTEIYQDTVLPHVKEAVLTK 1gph 3 3.0 BS02 AMP 3 1 M238 Y242 S283 D345 D346 S347 V349 R350 G351 T352 T353 M238 Y242 S283 D345 D346 S347 V349 R350 G351 T352 T353 E300 K305 Q315 K423 E300 K305 Q315 K423 2.4.2.14 0000287,0004044,0006164,0006189,0006541,0009113,0016757,0046872,0051536,0051539 P00497 8197456 467 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVDEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYPTEIYQDTVLPHVKEAVLTK 1gph 3 3.0 BS03 AMP 3 2 Y242 P281 D282 S283 K305 Y242 P281 D282 S283 K305 E300 K305 Q315 K423 E300 K305 Q315 K423 2.4.2.14 0000287,0004044,0006164,0006189,0006541,0009113,0016757,0046872,0051536,0051539 P00497 8197456 468 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVDEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYPTEIYQDTVLPHVKEAVLTK 1gph 3 3.0 BS04 AMP 4 2 I304 R307 I304 R307 E300 K305 Q315 K423 E300 K305 Q315 K423 2.4.2.14 0000287,0004044,0006164,0006189,0006541,0009113,0016757,0046872,0051536,0051539 P00497 8197456 468 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVDEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYPTEIYQDTVLPHVKEAVLTK 1gph 4 3.0 BS02 AMP 4 1 Y242 S283 D345 D346 S347 V349 R350 G351 T353 Y242 S283 D345 D346 S347 V349 R350 G351 T353 E300 K305 Q315 K423 E300 K305 Q315 K423 2.4.2.14 0000287,0004044,0006164,0006189,0006541,0009113,0016757,0046872,0051536,0051539 P00497 8197456 467 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVDEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYPTEIYQDTVLPHVKEAVLTK 1gph 4 3.0 BS03 AMP 4 2 Y242 S244 R245 P281 D282 S283 K305 Y242 S244 R245 P281 D282 S283 K305 E300 K305 Q315 K423 E300 K305 Q315 K423 2.4.2.14 0000287,0004044,0006164,0006189,0006541,0009113,0016757,0046872,0051536,0051539 P00497 8197456 468 CGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGEKLTAHKGQGLITEVFQNGELSKVKGKGAIGHVRYATAGGGGYENVQPLLFRSQNNGSLALAHNGNLVNATQLKQQLENQGSIFQTSSDTEVLAHLIKRSGHFTLKDQIKNSLSMLKGAYAFLIMTETEMIVALDPNGLRPLSIGMMGDAYVVASETCAFDVVGATYLREVEPGEMLIINDEGMKSERFSMNINRSICSMEYIYFSRPDSNIDGINVHSARKNLGKMLAQESAVEADVVTGVPDSSISAAIGYAEATGIPYELGLIKNRYVGRTFIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLREAGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHSVDEIRQEIGADTLSFLSVEGLLKGIGRKYDDSNCGQCLACFTGKYPTEIYQDTVLPHVKEAVLTK 1gpm A 2.2 BS02 AMP A 1 G233 L234 S235 V260 F315 G231 L232 S233 V258 F313 G59 C86 Y87 H181 E183 D239 K381 G57 C84 Y85 H179 E181 D237 K357 6.3.5.2 0003921,0003922,0005524,0005829,0006164,0006177,0006541,0016874,0042802,0046037 P04079 8548458 527 ENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFITVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAAKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE 1gpm B 2.2 BS02 AMP B 1 G233 L234 S235 V260 F315 G231 L232 S233 V258 F313 G59 C86 Y87 H181 E183 D239 K381 G57 C84 Y85 H179 E181 D237 K355 6.3.5.2 0003921,0003922,0005524,0005829,0006164,0006177,0006541,0016874,0042802,0046037 P04079 8548458 527 ENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFITVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE 1gpm C 2.2 BS02 AMP C 1 G233 L234 S235 V260 F315 G231 L232 S233 V258 F313 G59 C86 Y87 H181 E183 D239 K381 G57 C84 Y85 H179 E181 D237 K357 6.3.5.2 0003921,0003922,0005524,0005829,0006164,0006177,0006541,0016874,0042802,0046037 P04079 8548458 527 ENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFITVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAAKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE 1gpm D 2.2 BS02 AMP D 1 G233 L234 S235 V260 F315 G231 L232 S233 V258 F313 G59 C86 Y87 H181 E183 D239 K381 G57 C84 Y85 H179 E181 D237 K355 6.3.5.2 0003921,0003922,0005524,0005829,0006164,0006177,0006541,0016874,0042802,0046037 P04079 8548458 527 ENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFITVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE 1gts A 2.8 BS02 AMP A 1 E34 G42 H43 S46 T230 R260 L261 K270 E27 G35 H36 S39 T223 R253 L254 K263 6.1.1.18 0000166,0004812,0004819,0005524,0005737,0005829,0006412,0006418,0006424,0006425,0043039 P00962 8364025 999 TNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDT 1h3d A 2.7 BS01 AMP A 1 R16 E156 D169 L170 S172 T173 G174 A175 T176 R12 E152 D165 L166 S168 T169 G170 A171 T172 2.4.2.17 0000105,0000287,0003879,0005524,0005737,0005829,0016757,0046872 P60757 14741209 400 TRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME 1hdi A 1.8 BS01 AMP A 1 A214 G237 G238 L313 G340 V341 E343 D374 A211 G234 G235 L310 G337 V338 E340 D371 R38 K215 G373 G396 R35 K212 G370 G393 2.7.2.3 0004618,0005524,0005737,0005829,0006094,0006096,0016301,0016310,0043531 Q7SIB7 11178909 417 NKLTLDKLNVKGKRVVMRVDFNVPMAAAQITNNARIKAAVPSIKFCLDDGAKSVVLMSHLGRPDGSPMPDKYSLQPVAAELKSALGKAVLFLKDCVGPAVEKACADPAAGSVILLENLRFHVEEEGKGKDASGNKAAGEPAKIKAFRASLSALGDVYVNDAFGTAHRAHSSMVGVNLPKKAGAFLMKKELNYFAAAAESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEAGKKIVKNLMSKAAANGVKITLPVDFVTADKFDEQAKIGQATVASGIPAGWMGLDCGPKSSAKYSEAVARAKQIVWNGPVGVFEWEAFAQGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDNVSHVSTGGGASLELLEGKVLPGVDALSNV 1hto A 2.4 BS02 AMP A 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7475 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto B 2.4 BS02 AMP B 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7477 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto C 2.4 BS02 AMP C 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7479 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto D 2.4 BS02 AMP D 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7481 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto E 2.4 BS02 AMP E 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7483 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto F 2.4 BS02 AMP F 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7485 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto G 2.4 BS02 AMP G 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7487 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto H 2.4 BS02 AMP H 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7489 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto I 2.4 BS02 AMP I 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7491 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto J 2.4 BS02 AMP J 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7493 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto K 2.4 BS02 AMP K 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7495 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto L 2.4 BS02 AMP L 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7497 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto M 2.4 BS02 AMP M 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7499 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto N 2.4 BS02 AMP N 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7501 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto O 2.4 BS02 AMP O 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7503 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto P 2.4 BS02 AMP P 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7505 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto Q 2.4 BS02 AMP Q 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7507 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto R 2.4 BS02 AMP R 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7509 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto S 2.4 BS02 AMP S 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7511 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto T 2.4 BS02 AMP T 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7513 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto U 2.4 BS02 AMP U 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7515 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto V 2.4 BS02 AMP V 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7517 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto W 2.4 BS02 AMP W 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7519 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1hto X 2.4 BS02 AMP X 1 Y125 G127 E129 F225 H271 S273 R355 Y128 G130 E132 F231 H277 S279 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7521 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq A 2.4 BS02 AMP A 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7475 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq B 2.4 BS02 AMP B 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7477 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq C 2.4 BS02 AMP C 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7479 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq D 2.4 BS02 AMP D 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7481 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq E 2.4 BS02 AMP E 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7483 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq F 2.4 BS02 AMP F 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7485 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq G 2.4 BS02 AMP G 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7487 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq H 2.4 BS02 AMP H 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7489 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq I 2.4 BS02 AMP I 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7491 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq J 2.4 BS02 AMP J 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7493 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq K 2.4 BS02 AMP K 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7495 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq L 2.4 BS02 AMP L 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7497 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq M 2.4 BS02 AMP M 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7499 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq N 2.4 BS02 AMP N 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7501 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq O 2.4 BS02 AMP O 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7503 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq P 2.4 BS02 AMP P 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7505 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq Q 2.4 BS02 AMP Q 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7507 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq R 2.4 BS02 AMP R 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7509 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq S 2.4 BS02 AMP S 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7511 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq T 2.4 BS02 AMP T 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7513 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq U 2.4 BS02 AMP U 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7515 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq V 2.4 BS02 AMP V 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7517 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq W 2.4 BS02 AMP W 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7519 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htq X 2.4 BS02 AMP X 1 Y125 G127 E129 F225 H271 S273 W275 R355 Y128 G130 E132 F231 H277 S279 W281 R363 D50 E129 E131 E212 E220 H269 R339 E357 R359 D53 E132 E134 E218 E226 H275 R346 E365 R367 6.3.1.2 0000287,0001968,0003824,0004356,0005524,0005576,0005737,0005829,0005886,0006542,0009274,0010756,0016020,0016874,0019740,0035375,0046872,0051260 P9WN39 12146952 7521 TEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV 1htt A 2.6 BS02 AMP A 1 R113 G120 R121 Y122 F125 Q127 R259 T281 G308 R311 R110 G117 R118 Y119 F122 Q124 R205 T223 G250 R253 6.1.1.21 0004812,0004821,0005524,0005737,0005829,0006412,0006427,0042803 P60906 7556055 451 NIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEHVTLELNSIGSLEARANYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG 1htt B 2.6 BS02 AMP B 1 R113 E115 G120 R121 Y122 F125 Q127 R259 T281 G308 R311 R110 E112 G117 R118 Y119 F122 Q124 R196 T214 G241 R244 6.1.1.21 0004812,0004821,0005524,0005737,0005829,0006412,0006427,0042803 P60906 7556055 451 NIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEHVTLELNSIGDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG 1htt C 2.6 BS02 AMP C 1 R113 E115 G120 Y122 F125 Q127 R259 T281 G308 R311 R110 E112 G117 Y119 F122 Q124 R205 T223 G250 R253 6.1.1.21 0004812,0004821,0005524,0005737,0005829,0006412,0006427,0042803 P60906 7556055 451 NIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEHVTLELNSIGSLEARANYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG 1htt D 2.6 BS02 AMP D 1 R113 E115 G120 R121 Y122 F125 Q127 R259 T281 V282 G308 R311 R110 E112 G117 R118 Y119 F122 Q124 R196 T214 V215 G241 R244 6.1.1.21 0004812,0004821,0005524,0005737,0005829,0006412,0006427,0042803 P60906 7556055 451 NIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEHVTLELNSIGDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG 1j20 A 2.0 BS01 AMP A 1 A6 T13 A33 R92 H113 G114 F125 A6 T13 A33 R92 H113 G114 F125 D12 R92 D121 S173 D12 R92 D121 S168 6.3.4.5 0000050,0000053,0004055,0005524,0005737,0006526,0016874 P59846 12684518 510 MKIVLAYSGGLDTSIILKWLKETYRAEVIAFTADIGQGEEVEEAREKALRTGASKAIALDLKEEFVRDFVFPMMRAGAVYEGYYLLGTSIARPLIAKHLVRIAEEEGAEAIAHGATGKGNDQVRFELTAYALKPDIKVIAPWREWSFQGRKEMIAYAEAHGIPVPPYSMDANLLHISYEGGVLEDPWAEPPKGMFRMTQDPEEAPDAPEYVEVEFFEGDPVAVNGERLSPAALLQRLNEIGGRHGVGRVDIVENRFVGMKSRGVYETPGGTILYHARRAVESLTLDREVLHQRDMLSPKYAELVYYGFWYAPEREALQAYFDHVARSVTGVARLKLYKGNVYVVGRKAPKSLYRQDLVSFGYDQKDAEGFIKIQALRLRVRALVER 1j20 B 2.0 BS01 AMP B 1 A6 Y7 T13 A33 R92 H113 G114 F125 A6 Y7 T13 A33 R92 H113 G114 F125 D12 R92 D121 S173 D12 R92 D121 S168 6.3.4.5 0000050,0000053,0004055,0005524,0005737,0006526,0016874 P59846 12684518 2510 MKIVLAYSGGLDTSIILKWLKETYRAEVIAFTADIGQGEEVEEAREKALRTGASKAIALDLKEEFVRDFVFPMMRAGAVYEGYYLLGTSIARPLIAKHLVRIAEEEGAEAIAHGATGKGNDQVRFELTAYALKPDIKVIAPWREWSFQGRKEMIAYAEAHGIPVPPYSMDANLLHISYEGGVLEDPWAEPPKGMFRMTQDPEEAPDAPEYVEVEFFEGDPVAVNGERLSPAALLQRLNEIGGRHGVGRVDIVENRFVGMKSRGVYETPGGTILYHARRAVESLTLDREVLHQRDMLSPKYAELVYYGFWYAPEREALQAYFDHVARSVTGVARLKLYKGNVYVVGRKAPKSLYRQDLVSFGYDQKDAEGFIKIQALRLRVRALVER 1j20 C 2.0 BS01 AMP C 1 A6 T13 A33 R92 I95 G114 F125 D175 A6 T13 A33 R92 I95 G114 F125 D170 D12 R92 D121 S173 D12 R92 D121 S168 6.3.4.5 0000050,0000053,0004055,0005524,0005737,0006526,0016874 P59846 12684518 3510 MKIVLAYSGGLDTSIILKWLKETYRAEVIAFTADIGQGEEVEEAREKALRTGASKAIALDLKEEFVRDFVFPMMRAGAVYEGYYLLGTSIARPLIAKHLVRIAEEEGAEAIAHGATGKGNDQVRFELTAYALKPDIKVIAPWREWSFQGRKEMIAYAEAHGIPVPPYSMDANLLHISYEGGVLEDPWAEPPKGMFRMTQDPEEAPDAPEYVEVEFFEGDPVAVNGERLSPAALLQRLNEIGGRHGVGRVDIVENRFVGMKSRGVYETPGGTILYHARRAVESLTLDREVLHQRDMLSPKYAELVYYGFWYAPEREALQAYFDHVARSVTGVARLKLYKGNVYVVGRKAPKSLYRQDLVSFGYDQKDAEGFIKIQALRLRVRALVER 1j20 D 2.0 BS01 AMP D 1 A6 Y7 T13 A33 Q37 R92 G114 F125 A6 Y7 T13 A33 Q37 R92 G114 F125 D12 R92 D121 S173 D12 R92 D121 S168 6.3.4.5 0000050,0000053,0004055,0005524,0005737,0006526,0016874 P59846 12684518 4510 MKIVLAYSGGLDTSIILKWLKETYRAEVIAFTADIGQGEEVEEAREKALRTGASKAIALDLKEEFVRDFVFPMMRAGAVYEGYYLLGTSIARPLIAKHLVRIAEEEGAEAIAHGATGKGNDQVRFELTAYALKPDIKVIAPWREWSFQGRKEMIAYAEAHGIPVPPYSMDANLLHISYEGGVLEDPWAEPPKGMFRMTQDPEEAPDAPEYVEVEFFEGDPVAVNGERLSPAALLQRLNEIGGRHGVGRVDIVENRFVGMKSRGVYETPGGTILYHARRAVESLTLDREVLHQRDMLSPKYAELVYYGFWYAPEREALQAYFDHVARSVTGVARLKLYKGNVYVVGRKAPKSLYRQDLVSFGYDQKDAEGFIKIQALRLRVRALVER 1jp4 A 1.69 BS04 AMP A 1 D120 T195 H198 G219 G220 K224 F238 G242 C243 D247 D114 T189 H192 G213 G214 K218 F232 G236 C237 D241 D51 E74 D117 V119 D120 T122 D247 D47 E70 D111 V113 D114 T116 D241 3.1.3.57,3.1.3.7 0000287,0004441,0008150,0008441,0016787,0046854,0046872 Q9Z1N4 11812139 601 HNVLMRLVASAYSIAQKAGTIVRCVIAEGDLGIVQKTSATDLQTKADRMVQMSICSSLSRKFPKLTIIGEEDLPEVDQELIEDGQSEEILKQPCPSQYSAIKEEDLVVWVDPVDGTKEYTEGLLDNVTVLIGIAYEGKAIAGIINQPYYNYQAGPDAVLGRTIWGVLGLGAFGFQLKEAPAGKHIITTTRSHSNKLVTDCIAAMNPDNVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNPLQYDKEVKHMNSAGVLAALRNYEYYASRVPESVKSALIP 1jwb B 2.1 BS02 AMP D 1 G38 G40 G41 D62 F63 K86 L109 C128 T129 D130 N131 V134 G37 G39 G40 D61 F62 K85 L108 C127 T128 D129 N130 V133 R14 D130 R13 D129 2.7.7.80 0004792,0005515,0005524,0005737,0005829,0006777,0008146,0008641,0016779,0042803,0046872,0061605,1990133 P12282 11713534 82 AELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLIVGLGGLGCAASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVESARDALTRINPHIAITPVNALLDDAELAALIAEHDLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQITVFTYQDGEPCYRCLSRLFGEAGVMAPLIGVIGSLQAMEAIKMLAGYGKPASGKIVMYDAMTCQFREMKLMRNPGCEVCG 1k9y A 1.9 BS03 AMP A 1 G240 H241 D263 S264 K267 R281 Y288 D294 G239 H240 D262 S263 K266 R280 Y287 D293 D49 E72 D142 I144 D145 T147 D294 D48 E71 D141 I143 D144 T146 D293 3.1.3.7 0000103,0005575,0005634,0005737,0006790,0008441,0009086,0016078,0016787,0016791,0042538,0046854,0046872 P32179 12126627 501 ALERELLVATQAVRKASLLTKRIQSEVISHKDSTTITKNDNSPVTTGDYAAQTIIINAIKSNFPDDKVVGEESSSGLSDAFVSGILNEIKANDEVYNKNYKKDDFLFTNDQFPLKSLEDVRQIIDFGNYEGGRKGRFWCLDPIDGTKGFLRGEQFAVCLALIVDGVVQLGCIGCPNLVLSSYGAQDLKGHESFGYIFRAVRGLGAFYSPSSDAESWTKIHVRHLKDTKDMITLEGVEKGHSSHDEQTAIKNKLNISKSLHLDSQAKYCLLALGLADVYLRLPIKLSYQEKIWDHAAGNVIVHEAGGIHTDAMEDVPLDFGNGRTLATKGVIASSGPRELHDLVVSTSCDVIQSR 1ka0 A 1.8 BS01 AMP A 1 H241 D263 S264 K267 R281 Y288 D294 H239 D261 S262 K265 R279 Y286 D292 D49 E72 D142 I144 D145 T147 D294 D47 E70 D140 I142 D143 T145 D292 3.1.3.7 0000103,0005575,0005634,0005737,0006790,0008441,0009086,0016078,0016787,0016791,0042538,0046854,0046872 P32179 401 LERELLVATQAVRKASLLTKRIQSEVISHKDSTTITKNDNSPVTTGDYAAQTIIINAIKSNFPDDKVVGEESSSGLSDAFVSGILNEIKANDEVYNKNYKKDDFLFTNDQFPLKSLEDVRQIIDFGNYEGGRKGRFWCLDPIDGTKGFLRGEQFAVCLALIVDGVVQLGCIGCPNLVLSSYGAQDLKGHESFGYIFRAVRGLGAFYSPSSDAESWTKIHVRHLKDTKDMITLEGVEKGHSSHDEQTAIKNKLNISKSLHLDSQAKYCLLALGLADVYLRLPIKLSYQEKIWDHAAGNVIVHEAGGIHTDAMEDVPLDFGNGRTLATKGVIASSGPRELHDLVVSTSCDVIQSR 1kht B 2.5 BS01 AMP B 1 F39 G40 M43 R56 R60 Q71 T91 H92 V95 G104 R138 F38 G39 M42 R55 R59 Q70 T90 H91 V94 G103 R137 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43411 12860130 2193 KNKVVVVTGVPGVGSTTSSQLAMDNLRKEGVNYKMVSFGSVMFEVAKEENLVSDRDQMRKMDPETQKRIQKMAGRKIAEMAKESPVAVDTHSTVSTPKGYLPGLPSWVLNELNPDLIIVVETTGDEILMRRMSDETRVRDLDTASTIEQHQFMNRCAAMSYGVLTGATVKIVQNRNGLLDQAVEELTNVLR 1kht C 2.5 BS01 AMP C 1 F39 M43 R56 Q71 T91 H92 V95 G104 F38 M42 R55 Q70 T90 H91 V94 G103 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43411 12860130 3193 KNKVVVVTGVPGVGSTTSSQLAMDNLRKEGVNYKMVSFGSVMFEVAKEENLVSDRDQMRKMDPETQKRIQKMAGRKIAEMAKESPVAVDTHSTVSTPKGYLPGLPSWVLNELNPDLIIVVETTGDEILMRRMSDETRVRDLDTASTIEQHQFMNRCAAMSYGVLTGATVKIVQNRNGLLDQAVEELTNVLR 1kpf A 1.5 BS01 AMP A 1 D43 I44 N99 S107 V108 H112 H114 D28 I29 N84 S92 V93 H97 H99 3.4.22.-,3.9.1.- 0000118,0000166,0003824,0005080,0005515,0005634,0005654,0005737,0005829,0005856,0005886,0006355,0006508,0006915,0007165,0008234,0009154,0016787,0016926,0016929,0043530,0050850,0070062,0072332 P49773 9323207 200 DTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 1ktg A 1.8 BS04 AMP A 1 P29 H31 K36 Y76 K83 Y121 P28 H30 K35 Y75 K82 Y120 3.6.1.- 0004081,0005524,0005575,0006167,0006172,0006754,0006915,0008796,0015967,0016787,0019693,0043135 Q9U2M7 11937063 701 VVKAAGLVIYRKLAGKIEFLLLQASYPPHHWTPPKGHVDPGEDEWQAAIRETKEEANITKEQLTIHEDCHETLFYEAKGKPKSVKYWLAKLNNPDDVQLSHEHQNWKWCELEDAIKIADYAEMGSLLRKFSAFLAGF 1kz8 A 2.0 BS03 AMP A 1 Q20 G21 A24 G26 T27 G28 E29 M30 K112 Y113 R140 M177 Q12 G13 A16 G18 T19 G20 E21 M22 K96 Y97 R124 M161 D74 E97 E98 D118 L120 D121 E280 D58 E81 E82 D102 L104 D105 E264 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 12190310 737 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGVKKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1kz8 F 2.0 BS03 AMP F 1 G21 A24 G26 T27 E29 M30 K112 Y113 R140 M177 G13 A16 G18 T19 E21 M22 K96 Y97 R124 M161 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 12190310 837 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGVKKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1lgr A 2.79 BS03 AMP A 1 E207 T223 F225 H271 S273 R355 E201 T217 F219 H265 S267 R345 6.3.1.2 0003824,0004356,0005524,0005737,0006542,0016020,0016874,0016879,0019740,0030145,0046872,0051260 P0A1P6 7727369 471 SAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEPMDIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV 1lgr B 2.79 BS03 AMP B 1 E207 T223 F225 H271 S273 R355 E201 T217 F219 H265 S267 R345 6.3.1.2 0003824,0004356,0005524,0005737,0006542,0016020,0016874,0016879,0019740,0030145,0046872,0051260 P0A1P6 7727369 472 SAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEPMDIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV 1lgr C 2.79 BS03 AMP C 1 E207 T223 F225 H271 S273 R355 E201 T217 F219 H265 S267 R345 6.3.1.2 0003824,0004356,0005524,0005737,0006542,0016020,0016874,0016879,0019740,0030145,0046872,0051260 P0A1P6 7727369 473 SAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEPMDIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV 1lgr D 2.79 BS03 AMP D 1 E207 T223 F225 H271 S273 R355 E201 T217 F219 H265 S267 R345 6.3.1.2 0003824,0004356,0005524,0005737,0006542,0016020,0016874,0016879,0019740,0030145,0046872,0051260 P0A1P6 7727369 474 SAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEPMDIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV 1lgr E 2.79 BS03 AMP E 1 E207 T223 F225 H271 S273 R355 E201 T217 F219 H265 S267 R345 6.3.1.2 0003824,0004356,0005524,0005737,0006542,0016020,0016874,0016879,0019740,0030145,0046872,0051260 P0A1P6 7727369 475 SAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEPMDIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV 1lgr F 2.79 BS03 AMP F 1 E207 T223 F225 H271 S273 R355 E201 T217 F219 H265 S267 R345 6.3.1.2 0003824,0004356,0005524,0005737,0006542,0016020,0016874,0016879,0019740,0030145,0046872,0051260 P0A1P6 7727369 476 SAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEPMDIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV 1lgr G 2.79 BS03 AMP G 1 E207 T223 F225 H271 S273 R355 E201 T217 F219 H265 S267 R345 6.3.1.2 0003824,0004356,0005524,0005737,0006542,0016020,0016874,0016879,0019740,0030145,0046872,0051260 P0A1P6 7727369 477 SAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEPMDIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV 1lgr H 2.79 BS03 AMP H 1 E207 T223 F225 H271 S273 R355 E201 T217 F219 H265 S267 R345 6.3.1.2 0003824,0004356,0005524,0005737,0006542,0016020,0016874,0016879,0019740,0030145,0046872,0051260 P0A1P6 7727369 478 SAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEPMDIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV 1lgr I 2.79 BS03 AMP I 1 E207 T223 F225 H271 S273 R355 E201 T217 F219 H265 S267 R345 6.3.1.2 0003824,0004356,0005524,0005737,0006542,0016020,0016874,0016879,0019740,0030145,0046872,0051260 P0A1P6 7727369 479 SAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEPMDIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV 1lgr J 2.79 BS03 AMP J 1 E207 T223 F225 H271 S273 R355 E201 T217 F219 H265 S267 R345 6.3.1.2 0003824,0004356,0005524,0005737,0006542,0016020,0016874,0016879,0019740,0030145,0046872,0051260 P0A1P6 7727369 480 SAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEPMDIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV 1lgr K 2.79 BS03 AMP K 1 E207 T223 F225 H271 S273 R355 E201 T217 F219 H265 S267 R345 6.3.1.2 0003824,0004356,0005524,0005737,0006542,0016020,0016874,0016879,0019740,0030145,0046872,0051260 P0A1P6 7727369 481 SAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEPMDIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV 1lgr L 2.79 BS03 AMP L 1 E207 T223 F225 H271 S273 R355 E201 T217 F219 H265 S267 R345 6.3.1.2 0003824,0004356,0005524,0005737,0006542,0016020,0016874,0016879,0019740,0030145,0046872,0051260 P0A1P6 7727369 482 SAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEPMDIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV 1ltk A 3.0 BS01 AMP A 1 G213 A214 K215 G340 V341 D374 G215 A216 K217 G342 V343 D376 R39 K215 G373 G396 R41 K217 G375 G398 2.7.2.3 0004618,0005524,0005829,0006094,0006096,0016301,0016310,0043531 P27362 501 HHHLGNKLSISDLKDIKNKKVLVRVDFNVPIENGIIKDTNRITATLPTINHLKKEGASKIILISHCGRPDGLRNEKYTLKPVAETLKGLLGEEVLFLNDCVGKEVEDKINAAKENSVILLENLRFHIEEEGKGVDANGNKVKANKEDVEKFQNDLTKLADVFINDAFGTAHRAHSSMVGVKLNVKASGFLMKKELEYFSKALENPQRPLLAILGGAKVSDKIQLIKNLLDKVDRMIIGGGMAYTFKKVLNNMKIGTSLFDEAGSKIVGEIMEKAKAKNVQIFLPVDFKIADNFDNNANTKFVTDEEGIPDNWMGLDAGPKSIENYKDVILTSKTVIWNGPQGVFEMPNFAKGSIECLNLVVEVTKKGAITIVGGGDTASLVEQQNKKNEISHVSTGGGASLELLEGKELPGVLALSN 1ltk B 3.0 BS01 AMP B 1 A214 K215 K219 G237 G340 V341 E343 D374 A214 K215 K219 G237 G340 V341 E343 D374 R39 K215 G373 G396 R39 K215 G373 G396 2.7.2.3 0004618,0005524,0005829,0006094,0006096,0016301,0016310,0043531 P27362 502 HLGNKLSISDLKDIKNKKVLVRVDFNVPIENGIIKDTNRITATLPTINHLKKEGASKIILISHCGRPDGLRNEKYTLKPVAETLKGLLGEEVLFLNDCVGKEVEDKINAAKENSVILLENLRFHIEEEGKGVDANGNKVKANKEDVEKFQNDLTKLADVFINDAFGTAHRAHSSMVGVKLNVKASGFLMKKELEYFSKALENPQRPLLAILGGAKVSDKIQLIKNLLDKVDRMIIGGGMAYTFKKVLNNMKIGTSLFDEAGSKIVGEIMEKAKAKNVQIFLPVDFKIADNFDNNANTKFVTDEEGIPDNWMGLDAGPKSIENYKDVILTSKTVIWNGPQGVFEMPNFAKGSIECLNLVVEVTKKGAITIVGGGDTASLVEQQNKKNEISHVSTGGGASLELLEGKELPGVLALSN 1ltk C 3.0 BS01 AMP C 1 G213 A214 K215 G237 G238 G340 V341 E343 D374 G221 A222 K223 G245 G246 G348 V349 E351 D382 R39 K215 G373 G396 R47 K223 G381 G404 2.7.2.3 0004618,0005524,0005829,0006094,0006096,0016301,0016310,0043531 P27362 503 HSMHHHHHHLGNKLSISDLKDIKNKKVLVRVDFNVPIENGIIKDTNRITATLPTINHLKKEGASKIILISHCGRPDGLRNEKYTLKPVAETLKGLLGEEVLFLNDCVGKEVEDKINAAKENSVILLENLRFHIEEEGKGVDANGNKVKANKEDVEKFQNDLTKLADVFINDAFGTAHRAHSSMVGVKLNVKASGFLMKKELEYFSKALENPQRPLLAILGGAKVSDKIQLIKNLLDKVDRMIIGGGMAYTFKKVLNNMKIGTSLFDEAGSKIVGEIMEKAKAKNVQIFLPVDFKIADNFDNNANTKFVTDEEGIPDNWMGLDAGPKSIENYKDVILTSKTVIWNGPQGVFEMPNFAKGSIECLNLVVEVTKKGAITIVGGGDTASLVEQQNKKNEISHVSTGGGASLELLEGKELPGVLALSNK 1mb9 A 2.11 BS03 AMP A 1 V247 L248 S254 S272 M273 Y326 L330 G347 Y348 V235 L236 S242 S260 M261 Y314 L318 G335 Y336 A76 G77 D322 Y348 E382 K443 A70 G71 D310 Y336 E370 K431 6.3.3.4 0004066,0005524,0005829,0006529,0016874,0033050,0034027,0046872 P0DJQ7 12409610 706 PVLPAAFGFLASARTGAPGPVFATRGSHTDIDTPQGERSLAATLVHAPSVAPDRAVARSLTGAPTTAVLAGEIYNRDELLSVLPAGPAPEGDAELVLRLLERYDLHAFRLVNGRFATVVRTGDRVLLATDHAGSVPLYTCVAPGEVRASTEAKALAAFPLADARRVAGLTGVYQVPAGAVMDIDLGSGTAVTHRTWTPGLSRRILPEGEAVAAVRAALEKAVAQRVTPGDTPLVVLSGGIDSSGVAACAHRAAGELDTVSMGTDTSNEFREARAVVDHLRTRHREITIPTTELLAQLPYAVWASESVDPDIIEYLLPLTALYRALDGPERRILTGYGADIPLGGMHREDRLPALDTVLAHDMATFDGLNEMSPVLSTLAGHWTTHPYWDREVLDLLVSLEAGLKRRHGRDKWVLRAAMADALPAETVNRPKSSFSRLLLDHGVAEDRVHEAKRQVVRELFDLTVGGGRHPSEVDTDDVVRSVADR 1mc1 A 2.16 BS03 AMP A 1 V247 S249 S254 S272 M273 G347 K443 V446 V231 S233 S238 S256 M257 G331 K427 V430 A76 G77 D322 Y348 E382 K443 A65 G66 D306 Y332 E366 K427 6.3.3.4 0004066,0005524,0005829,0006529,0016874,0033050,0034027,0046872 P0DJQ7 12409610 702 VLPAAFGFLASARGPVFATRGSHTDIDTPQGERSLAATLVHAPSVAPDRAVARSLTGAPTTAVLAGEIYNRDELLSVLPAGPAPEGDAELVLRLLERYDLHAFRLVNGRFATVVRTGDRVLLATDHAGSVPLYTCVAPGEVRASTEAKALAAGFPLADARRVAGLTGVYQVPAGAVMDIDLGSGTAVTHRTWTPGLSRRILPEGEAVAAVRAALEKAVAQRVTPGDTPLVVLSGGIDSSGVAACAHRAAGELDTVSMGTDTSNEFREARAVVDHLRTRHREITIPTTELLAQLPYAVWASESVDPDIIEYLLPLTALYRALDGPERRILTGYGADIPLGGMHREDRLPALDTVLAHDMATFDGLNEMSPVLSTLAGHWTTHPYWDREVLDLLVSLEAGLKRRHGRDKWVLRAAMADALPAETVNRPKLGVHEGSGTTSSFSRLLLDHGVAEDRVHEAKRQVVRELFDLTVGGGRHPSEVDTDDVVRSVADR 1mc1 B 2.16 BS03 AMP B 1 V247 L248 S272 M273 L330 G347 Y348 V245 L246 S270 M271 L328 G345 Y346 A76 G77 D322 Y348 E382 K443 A74 G75 D320 Y346 E380 K441 6.3.3.4 0004066,0005524,0005829,0006529,0016874,0033050,0034027,0046872 P0DJQ7 12409610 705 APVLPAAFGFLASARTGGGRAPGPVFATRGSHTDIDTPQGERSLAATLVHAPSVAPDRAVARSLTGAPTTAVLAGEIYNRDELLSVLPAGPAPEGDAELVLRLLERYDLHAFRLVNGRFATVVRTGDRVLLATDHAGSVPLYTCVAPGEVRASTEAKALAAHRDPKGFPLADARRVAGLTGVYQVPAGAVMDIDLGSGTAVTHRTWTPGLSRRILPEGEAVAAVRAALEKAVAQRVTPGDTPLVVLSGGIDSSGVAACAHRAAGELDTVSMGTDTSNEFREARAVVDHLRTRHREITIPTTELLAQLPYAVWASESVDPDIIEYLLPLTALYRALDGPERRILTGYGADIPLGGMHREDRLPALDTVLAHDMATFDGLNEMSPVLSTLAGHWTTHPYWDREVLDLLVSLEAGLKRRHGRDKWVLRAAMADALPAETVNRPKLTSSFSRLLLDHGVAEDRVHEAKRQVVRELFDLTVGGGRHPSEVDTDDVVRSVADRT 1md9 A 2.8 BS01 AMP A 1 G191 G307 A308 K309 V329 F330 G331 M332 D413 V425 R428 K519 G191 G307 A308 K309 V329 F330 G331 M332 D413 V425 R428 K519 S190 S210 H234 A333 E334 N434 K439 K519 S190 S210 H234 A333 E334 N434 K439 K519 6.2.1.71 0005524,0005737,0008668,0016874,0019290 P40871 12221282 600 MLKGFTPWPDELAETYRKNGCWAGETFGDLLRDRAAKYGDRIAITCGNTHWSYRELDTRADRLAAGFQKLGIQQKDRVVVQLPNIKEFFEVIFALFRLGALPVFALPSHRSSEITYFCEFAEAAAYIIPDAYSGFDYRSLARQVQSKLPTLKNIIVAGEAEEFLPLEDLHTEPVKLPEVKSSDVAFLQLSGGSTGLSKLIPRTHDDYIYSLKRSVEVCWLDHSTVYLAALPMAHNYPLSSPGVLGVLYAGGRVVLSPSPSPDDAFPLIEREKVTITALVPPLAMVWMDAASSRRDDLSSLQVLQVGGAKFSAEAARRVKAVFGCTLQQVFGMAEGLVNYTRLDDPEEIIVNTQGKPMSPYDESRVWDDHDRDVKPGETGHLLTRGPYTIRGYYKAEEHNAASFTEDGFYRTGDIVRLTRDGYIVVEGRAKDQINRGGEKVAAEEVENHLLAHPAVHDAAMVSMPDQFLGERSCVFIIPRDEAPKAAELKAFLRERGLAAYKIPDRVEFVESFPQTGVGKVSKKALREAISEKLLAG 1mdb A 2.15 BS01 AMP A 1 H234 G307 A308 K309 V329 F330 G331 M332 A333 D413 V425 R428 K519 H234 G307 A308 K309 V329 F330 G331 M332 A333 D413 V425 R428 K519 S190 S210 H234 A333 E334 N434 K439 K519 S190 S210 H234 A333 E334 N434 K439 K519 6.2.1.71 0005524,0005737,0008668,0016874,0019290 P40871 12221282 600 MLKGFTPWPDELAETYRKNGCWAGETFGDLLRDRAAKYGDRIAITCGNTHWSYRELDTRADRLAAGFQKLGIQQKDRVVVQLPNIKEFFEVIFALFRLGALPVFALPSHRSSEITYFCEFAEAAAYIIPDAYSGFDYRSLARQVQSKLPTLKNIIVAGEAEEFLPLEDLHTEPVKLPEVKSSDVAFLQLSGGSTGLSKLIPRTHDDYIYSLKRSVEVCWLDHSTVYLAALPMAHNYPLSSPGVLGVLYAGGRVVLSPSPSPDDAFPLIEREKVTITALVPPLAMVWMDAASSRRDDLSSLQVLQVGGAKFSAEAARRVKAVFGCTLQQVFGMAEGLVNYTRLDDPEEIIVNTQGKPMSPYDESRVWDDHDRDVKPGETGHLLTRGPYTIRGYYKAEEHNAASFTEDGFYRTGDIVRLTRDGYIVVEGRAKDQINRGGEKVAAEEVENHLLAHPAVHDAAMVSMPDQFLGERSCVFIIPRDEAPKAAELKAFLRERGLAAYKIPDRVEFVESFPQTGVGKVSKKALREAISEKLLAG 1mf0 A 2.5 BS03 AMP A 1 D43 N68 A69 T162 T163 V270 T271 V305 G306 D17 N42 A43 T136 T137 V244 T245 V279 G280 D43 K46 G70 H71 N256 D17 K20 G44 H45 N230 6.3.4.4 0000166,0000287,0004019,0005515,0005525,0005737,0006163,0006164,0006167,0016020,0016874,0044208,0044209,0046872 P28650 12186864 1454 AATGSRVTVVLGAQWGDEGKGKVVDLLATDADIVSRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDFDEFSARFKNLAHQHQSMFPTLEIDVEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKVLVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGDLLQNRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLSEIKVGISYKLNGKRIPYFPANQEILQKVEVEYETLPGWKADTTGARKWEDLPPQAQSYVRFVENHMGVAVKWVGVGKSRESMIQLF 1mf1 A 2.7 BS01 AMP A 1 D43 N68 G161 T162 T163 N256 L260 V270 T271 V305 D16 N41 G134 T135 T136 N229 L233 V243 T244 V278 D43 K46 G70 H71 N256 D16 K19 G43 H44 N229 6.3.4.4 0000166,0000287,0004019,0005515,0005525,0005737,0006163,0006164,0006167,0016020,0016874,0044208,0044209,0046872 P28650 12186864 459 ATGSRVTVVLGAQWGDEGKGKVVDLLATDADIVSRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDFDEFSARFKNLAHQHQSMFPTLEIDVEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKVLVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGDLLQNRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLSEIKVGISYKLNGKRIPYFPANQEILQKVEVEYETLPGWKADTTGARKWEDLPPQAQSYVRFVENHMGVAVKWVGVGKSRESMIQLF 1mzv A 2.2 BS01 AMP A 1 R37 F42 A43 R82 D146 D147 V148 A150 T151 G152 T154 R36 F41 A42 R81 D145 D146 V147 A149 T150 G151 T153 R82 E120 R81 E119 2.4.2.7 0000166,0003999,0016757 O77103 14726202 301 SLKEIGPNSLLLEDSHSLSQLLKKNYRWYSPIFSPRNVPRFADVSSITESPETLKAIRDFLVERYRTMSPAPTHILGFDARGFLFGPMIAVELGIPFVLMRKADKNAGLLIRSEPYEKEYKEAAPEVMTIRHGSIGKNSRVVLIDDVLATGGTALSGLQLVEASGAEVVEMVSILTIPFLKAAERIHSTAGGRYKNVRFIGLLSEDVLTEANCGDL 1nh8 A 1.8 BS01 AMP A 1 V155 G157 S158 G159 R160 T161 V155 G157 S158 G159 R160 T161 2.4.2.17 0000105,0000287,0003879,0005515,0005524,0005737,0005886,0016208,0016757,0046872 P9WMN1 12511575 288 MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVEFFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVRERLALGFGSSSFRYAAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISVQLGVADAIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIAPLADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF 1nks C 2.57 BS01 AMP C 1 N36 Y37 G38 M41 R54 R58 Q69 T92 H93 I96 G105 R139 N36 Y37 G38 M41 R54 R58 Q69 T92 H93 I96 G105 R139 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P35028 9733648 195 MKIGIVTGIPGVGKSTVLAKVKEILDNQGINNKIINYGDFMLATALKLGYAKDRDEMRKLSVEKQKKLQIDAAKGIAEEARAGGEGYLFIDTHAVIRTPSGYLPGLPSYVITEINPSVIFLLEADPKIILSRQKRDTTRNRNDYSDESVILETINFARYAATASAVLAGSTVKVIVNVEGDPSIAANEIIRSMK 1nks D 2.57 BS01 AMP D 1 N36 Y37 G38 M41 R54 Q69 T92 H93 I96 G105 N36 Y37 G38 M41 R54 Q69 T92 H93 I96 G105 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P35028 9733648 195 MKIGIVTGIPGVGKSTVLAKVKEILDNQGINNKIINYGDFMLATALKLGYAKDRDEMRKLSVEKQKKLQIDAAKGIAEEARAGGEGYLFIDTHAVIRTPSGYLPGLPSYVITEINPSVIFLLEADPKIILSRQKRDTTRNRNDYSDESVILETINFARYAATASAVLAGSTVKVIVNVEGDPSIAANEIIRSMK 1nks F 2.57 BS01 AMP F 1 N36 Y37 G38 M41 R54 M57 R58 Q69 T92 H93 I96 G105 R139 N36 Y37 G38 M41 R54 M57 R58 Q69 T92 H93 I96 G105 R139 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P35028 9733648 195 MKIGIVTGIPGVGKSTVLAKVKEILDNQGINNKIINYGDFMLATALKLGYAKDRDEMRKLSVEKQKKLQIDAAKGIAEEARAGGEGYLFIDTHAVIRTPSGYLPGLPSYVITEINPSVIFLLEADPKIILSRQKRDTTRNRNDYSDESVILETINFARYAATASAVLAGSTVKVIVNVEGDPSIAANEIIRSMK 1nsy A 2.0 BS03 AMP A 1 G44 I45 S46 L79 Q84 R139 T157 T208 A209 G44 I45 S46 L79 Q84 R139 T157 T208 A209 D50 E162 D50 E162 6.3.1.5 0003952,0004359,0005524,0005737,0008795,0009435,0016874,0030435,0046872 P08164 8895556 4000 SMQEKIMRELHVKPSIDPKQEIEDRVNFLKQYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVESIREEGGDAQFIAVRLPHGTQQDEDDAQLALKFIKPDKSWKFDIKSTVSAFSDQYQQETGDQLTDFNKGNVKARTRMIAQYAIGGQEGLLVLGTDHAAEAVTGFFTKYGDGGADLLPLTGLTKRQGRTLLKELGAPERLYLKEPTADLLDEKPQQSDETELGISYDEIDDYLEGKEVSAKVSEALEKRYSMTEHKRQVPASMFDDWWK 1nsy B 2.0 BS04 AMP B 1 G44 I45 S46 L79 Q84 R139 T157 D173 T208 A209 G44 I45 S46 L79 Q84 R139 T157 D173 T208 A209 D50 E162 D50 E162 6.3.1.5 0003952,0004359,0005524,0005737,0008795,0009435,0016874,0030435,0046872 P08164 8895556 5000 SMQEKIMRELHVKPSIDPKQEIEDRVNFLKQYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVESIREEGGDAQFIAVRLPHGTQQDEDDAQLALKFIKPDKSWKFDIKSTVSAFSDQYQQETGDQLTDFNKGNVKARTRMIAQYAIGGQEGLLVLGTDHAAEAVTGFFTKYGDGGADLLPLTGLTKRQGRTLLKELGAPERLYLKEPTADLLDEKPQQSDETELGISYDEIDDYLEGKEVSAKVSEALEKRYSMTEHKRQVPASMFDDWWK 1nv7 A 2.15 BS04 AMP A 1 E1020 G1021 T1027 E1029 M1030 K1112 Y1113 V1160 M1177 E12 G13 T19 E21 M22 K104 Y105 V152 M169 D1068 D1074 E1097 E1098 D1118 L1120 D1121 E1280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 12595529 3337 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1nv7 B 2.15 BS04 AMP B 1 E2020 G2021 T2027 E2029 M2030 K2112 Y2113 R2140 V2160 M2177 E12 G13 T19 E21 M22 K104 Y105 R132 V152 M169 D2068 D2074 E2097 E2098 D2118 L2120 D2121 E2280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 12595529 4337 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1o0b A 2.7 BS03 AMP A 1 F31 P33 H40 G42 H43 S46 R260 L261 F24 P26 H33 G35 H36 S39 R253 L254 6.1.1.18 0000166,0004812,0004819,0005524,0005737,0005829,0006412,0006418,0006424,0006425,0043039 P00962 12691748 998 TNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDT 1o0c A 2.7 BS03 AMP A 1 F31 P33 H40 G42 H43 S46 T230 R260 L261 K270 F24 P26 H33 G35 H36 S39 T223 R253 L254 K263 6.1.1.18 0000166,0004812,0004819,0005524,0005737,0005829,0006412,0006418,0006424,0006425,0043039 P00962 12691748 998 TNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDT 1o94 C 2.0 BS01 AMP C 1 A6 V7 K8 N36 D39 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 A6 V7 K8 N35 D38 V62 V98 A116 G117 Q119 S120 Y125 A126 S127 T128 ? 0000166,0009055 P53570 12567183 1236 MKILVAVKQTAALEEDFEIRDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASLRGIKQAATKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIP 1o94 E 2.0 BS01 AMP E 1 A6 V7 K8 N36 D39 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 A6 V7 K8 N36 D39 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 ? 0000166,0009055 P53570 12567183 1237 MKILVAVKQTAALEEDFEIREDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASLRGIKQAATKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPE 1o95 C 3.7 BS01 AMP C 1 A6 V7 D39 V64 V100 A118 G119 Q121 S122 A128 S129 T130 A6 V7 D38 V62 V98 A116 G117 Q119 S120 A126 S127 T128 ? 0000166,0009055 P53570 12567183 1236 MKILVAVKQTAALEEDFEIRDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASLRGIKQAATKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIP 1o95 E 3.7 BS01 AMP E 1 V7 K8 D39 V64 V100 A118 G119 Q121 S122 A126 Y127 A128 T130 V7 K8 D39 V64 V100 A118 G119 Q121 S122 A126 Y127 A128 T130 ? 0000166,0009055 P53570 12567183 1237 MKILVAVKQTAALEEDFEIREDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASLRGIKQAATKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPE 1o96 A 3.1 BS01 AMP A 1 A6 V7 K8 D39 V64 V100 A118 G119 Q121 S122 Y127 A128 T130 A6 V7 K8 D38 V63 V99 A117 G118 Q120 S121 Y126 A127 T129 ? 0000166,0009055 P53570 12567183 1263 MKILVAVKQTAALEEDFEIRDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASLRGIKQAATKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPEKGRATMIEGTISEQAAKIIQIINEFK 1o96 C 3.1 BS01 AMP C 1 A6 V7 K8 D39 S63 V64 V100 L104 A118 G119 Q121 S122 Y127 A128 T130 A6 V7 K8 D38 S62 V63 V99 L103 A117 G118 Q120 S121 Y126 A127 T129 ? 0000166,0009055 P53570 12567183 1262 MKILVAVKQTAALEEDFEIRDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASLRGIKQAATKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPEKGRATMIEGTISEQAAKIIQIINEF 1o96 E 3.1 BS01 AMP E 1 A6 V7 K8 D39 S63 V64 V100 A118 G119 Q121 S122 Y127 A128 T130 A6 V7 K8 D38 S62 V63 V99 A117 G118 Q120 S121 Y126 A127 T129 ? 0000166,0009055 P53570 12567183 1262 MKILVAVKQTAALEEDFEIRDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASLRGIKQAATKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPEKGRATMIEGTISEQAAKIIQIINEF 1o96 Q 3.1 BS01 AMP Q 1 A6 V7 K8 D39 S63 V64 V100 A118 G119 Q121 S122 Y127 A128 T130 A6 V7 K8 D38 S62 V63 V99 A117 G118 Q120 S121 Y126 A127 T129 ? 0000166,0009055 P53570 12567183 1262 MKILVAVKQTAALEEDFEIRDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPEKGRATMIEGTISEQAAKIIQIINEF 1o97 C 1.6 BS01 AMP C 1 A6 V7 K8 D39 S63 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 A6 V7 K8 D39 S63 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 ? 0000166,0009055 P53570 12567183 1262 MKILVAVKQTAALEEDFEIREDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPEKGRATMIEGTISEQAAKIIQIINEF 1obd A 1.4 BS03 AMP A 1 E62 I79 L107 L108 E61 I78 L106 L107 6.3.2.6 0004639,0005515,0005524,0005634,0005737,0006164,0006189,0016874 P27616 315 SITKTELDGILPLVARGKVRDIYEVDAGTLLFVATDRISAYDVIMENSIPEKGILLTKLSEFWFKFLSNDVRNHLVDIAPGKTIFDYLPAKLSEPKYKTQLEDRSLLVHKHKLIPLEVIVRGYITGSAWKEYVKTGTVHGLKQPQGLKESQEFPEPIFTPSTKADENISPAQAAELVGEDLSRRVAELAVKLYSKCKDYAKEKGIIIADTKFEFGIDEKTNEIILVDEVLTPDSSRFWNGASYKVGESQDSYDKQFLRDWLTANKLNGVNGVKMPQDIVDRTRAKYIEAYETLTGSKW 1obg A 2.05 BS01 AMP A 1 R21 I23 F33 H75 K111 H112 K164 E219 V232 D233 R20 I22 F32 H74 K110 H111 K163 E218 V231 D232 6.3.2.6 0004639,0005515,0005524,0005634,0005737,0006164,0006189,0016874 P27616 307 SITKTELDGILPLVARGKVRDIYEVDAGTLLFVATDRISAYDVIMENSIPEKGILLTKLSEFWFKFLSNDVRNHLVDIAPGKTIFDYLPAKLSEPKYKTQLEDRSLLVHKHKLIPLEVIVRGYITGSAWKEYVKTGTVHGLKQPQGLKESQEFPEPIFTPSTKAEQGEHDENISPAQAAELVGEDLSRRVAELAVKLYSKCKDYAKEKGIIIADTKFEFGIDEKTNEIILVDEVLTPDSSRFWNGASYKVGESQDSYDKQFLRDWLTANKLNGVNGVKMPQDIVDRTRAKYIEAYETLTGSKWSH 1obg A 2.05 BS02 AMP A 2 E62 V77 I79 I85 L107 L108 E61 V76 I78 I84 L106 L107 6.3.2.6 0004639,0005515,0005524,0005634,0005737,0006164,0006189,0016874 P27616 309 SITKTELDGILPLVARGKVRDIYEVDAGTLLFVATDRISAYDVIMENSIPEKGILLTKLSEFWFKFLSNDVRNHLVDIAPGKTIFDYLPAKLSEPKYKTQLEDRSLLVHKHKLIPLEVIVRGYITGSAWKEYVKTGTVHGLKQPQGLKESQEFPEPIFTPSTKAEQGEHDENISPAQAAELVGEDLSRRVAELAVKLYSKCKDYAKEKGIIIADTKFEFGIDEKTNEIILVDEVLTPDSSRFWNGASYKVGESQDSYDKQFLRDWLTANKLNGVNGVKMPQDIVDRTRAKYIEAYETLTGSKWSH 1obt A 2.8 BS01 AMP A 1 Y80 G121 N122 Y123 I172 Y75 G116 N117 Y118 I167 V81 E177 H180 V76 E172 H175 3.2.2.22 0017148,0030598 P02879 8780513 701 YPIINFTTAGATVQSYTNFIRAVRGRLTTGADVRHEIPVLPNRVGLPINQRFILVELSNHAELSVTLALDVTNAYVVGYRAGNSAYFFHPDNQEDAEAITHLFTDVQNRYTFAFGGNYDRLEQLAGNLRENIELGNGPLEEAISALYYYSTGGTQLPTLARSFIICIQMISEAAHFQYIEGEMRTRIRYNRRSAPDPSVITLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFSVYDVSILIPIIALMVYRCAPPP 1ore A 2.1 BS01 AMP A 1 F26 R27 R67 D127 D128 L129 A131 T132 G133 T135 F25 R26 R66 D126 D127 L128 A130 T131 G132 T134 R67 E104 R66 E103 2.4.2.7 0002055,0003999,0005515,0005576,0005654,0005737,0005829,0006166,0006168,0007625,0016208,0016757,0032263,0032264,0034774,0044209,0046083,0070062 P07741 15196008 1001 ADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 1p8l A 2.95 BS01 AMP A 1 K27 I28 E67 F98 M164 L184 K186 K26 I27 E66 F97 M163 L183 K185 ? 0000166,0003909,0003910,0005524,0006260,0006281,0006310,0016874 O41026 12930960 301 AITKPLLAATLENIEDVQFPCLATPKIDGIRSVKQTQMLSRTFKPIRNSVMNRLLTELLPEGSDGEISIEGATFQDTTSAVMTGHKMYNAKFSYYWFDYVTDDPLKKYIDRVEDMKNYITVHPHILEHAQVKIIPLIPVEINNITELLQYERDVLSKGFEGVMIRKPDGKYKFGRSTLKEGILLKMKQFKDAEATIISMTALFKNFGYEDVMGSIEVDYDGVVFSIGTGFDADQRRDFWQNKESYIGKMVKFKYFEMGSKDCPRFPVFIGIRHEED 1ptw A 2.3 BS02 AMP A 1 H160 D201 D318 L319 N321 F340 Q369 F372 H82 D123 D240 L241 N243 F262 Q291 F294 3.1.4.53 0004114,0007165,0008081 Q08499 14609333 507 IPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 1ptw B 2.3 BS02 AMP B 1 H160 D201 D318 L319 N321 I336 Q369 F372 H75 D116 D233 L234 N236 I251 Q284 F287 3.1.4.53 0004114,0007165,0008081 Q08499 14609333 508 TEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 1ptw C 2.3 BS02 AMP C 1 H160 D318 L319 N321 F340 Q369 F372 H75 D233 L234 N236 F255 Q284 F287 3.1.4.53 0004114,0007165,0008081 Q08499 14609333 509 TEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 1ptw D 2.3 BS02 AMP D 1 H160 D201 D318 L319 N321 Q369 F372 H82 D123 D240 L241 N243 Q291 F294 3.1.4.53 0004114,0007165,0008081 Q08499 14609333 510 IPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 1pyg A 2.87 BS01 AMP A 1 W67 Q71 Y75 R309 R310 F316 G317 W58 Q62 Y66 R274 R275 F281 G282 H377 K568 R569 K574 T676 K680 H342 K533 R534 K539 T641 K645 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 -logKd/Ki=5.52, Kd=3uM P00489 1962195 843 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPQAVLDRNLAENISKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 1pyg A 2.87 BS03 AMP B 1 D42 N44 V45 D33 N35 V36 H377 K568 R569 K574 T676 K680 H342 K533 R534 K539 T641 K645 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 -logKd/Ki=5.52, Kd=3uM P00489 1962195 843 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPQAVLDRNLAENISKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 1pyg B 2.87 BS01 AMP A 1 D42 N44 V45 D23 N25 V26 H377 K568 R569 K574 T676 K680 H332 K523 R524 K529 T631 K635 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 -logKd/Ki=5.52, Kd=3uM P00489 1962195 843 GVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPQAVLDRNLAENISKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 1pyg B 2.87 BS02 AMP B 1 W67 Q71 Y75 R309 R310 F316 G317 W48 Q52 Y56 R264 R265 F271 G272 H377 K568 R569 K574 T676 K680 H332 K523 R524 K529 T631 K635 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 -logKd/Ki=5.52, Kd=3uM P00489 1962195 843 GVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPQAVLDRNLAENISKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 1pyg C 2.87 BS01 AMP C 1 W67 Q71 Y75 R309 R310 F316 W58 Q62 Y66 R274 R275 F281 H377 K568 R569 K574 T676 K680 H342 K533 R534 K539 T641 K645 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 1962195 843 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPQAVLDRNLAENISKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 1pyg C 2.87 BS03 AMP D 1 D42 N44 D33 N35 H377 K568 R569 K574 T676 K680 H342 K533 R534 K539 T641 K645 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 1962195 843 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPQAVLDRNLAENISKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 1pyg D 2.87 BS01 AMP C 1 D42 N44 V45 D33 N35 V36 H377 K568 R569 K574 T676 K680 H342 K533 R534 K539 T641 K645 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 1962195 843 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPQAVLDRNLAENISKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 1pyg D 2.87 BS02 AMP D 1 Q71 Y75 R309 R310 K315 F316 G317 C318 Q62 Y66 R274 R275 K280 F281 G282 C283 H377 K568 R569 K574 T676 K680 H342 K533 R534 K539 T641 K645 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 1962195 843 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPQAVLDRNLAENISKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 1qb8 A 2.0 BS02 AMP A 1 F42 A43 R82 D146 V148 A150 T151 G152 T154 F41 A42 R81 D145 V147 A149 T150 G151 T153 R82 E120 R81 E119 2.4.2.7 0000166,0003999,0016757,0046872 Q27679 10393170 300 PFKEVSPNSFLLDDSHALSQLLKKSYRWYSPVFSPRNVPRFADVSSITESPETLKAIRDFLVQRYRAMSPAPTHILGFDARGFLFGPMIAVELEIPFVLMRKADKNAGLLIRSEPYEKEYKEAAPEVMTIRYGSIGKGSRVVLIDDVLATGGTALSGLQLVEASDAVVVEMVSILSIPFLKAAEKIHSTANSRYKDIKFISLLSDDALTEENCGDSKNYTGPRVLSCGDVLAEHPH 1qf6 A 2.9 BS03 AMP A 1 R363 E365 R375 V376 F379 Q381 Q479 C480 G516 S517 R520 R362 E364 R374 V375 F378 Q380 Q478 C479 G515 S516 R519 C334 R363 Q381 D383 H385 K465 H511 C333 R362 Q380 D382 H384 K464 H510 6.1.1.3 0000049,0000166,0000900,0002161,0003723,0004812,0004829,0005515,0005524,0005737,0005829,0006412,0006417,0006418,0006435,0008270,0042803,0043039,0045947,0046677,0046872,0048027,0106074 P0A8M3 10319817 1002 PVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE 1qgx A 1.6 BS03 AMP A 1 G240 H241 D263 S264 K267 R281 Y288 D294 G239 H240 D262 S263 K266 R280 Y287 D293 D49 E72 D142 I144 D145 T147 D294 D48 E71 D141 I143 D144 T146 D293 3.1.3.7 0000103,0005575,0005634,0005737,0006790,0008441,0009086,0016078,0016787,0016791,0042538,0046854,0046872 P32179 10656801 405 ALERELLVATQAVRKASLLTKRIQSEVISHKDSTTITKNDNSPVTTGDYAAQTIIINAIKSNFPDDKVVGEESSSGLSDAFVSGILNEIKANDEVYNKNYKKDDFLFTNDQFPLKSLEDVRQIIDFGNYEGGRKGRFWCLDPIDGTKGFLRGEQFAVCLALIVDGVVQLGCIGCPNLVLSSYGAQDLKGHESFGYIFRAVRGLGAFYSPSSDAESWTKIHVRHLKDTKDMITLEGVEKGHSSHDEQTAIKNKLNISKSLHLDSQAKYCLLALGLADVYLRLPIKLSYQEKIWDHAAGNVIVHEAGGIHTDAMEDVPLDFGNGRTLATKGVIASSGPRELHDLVVSTSCDVIQSR 1rao A 1.56 BS01 AMP A 1 L70 Q74 R92 D97 I98 R110 L111 T112 L70 Q74 R92 D97 I98 R110 L111 T112 R82 R92 D95 D97 R82 R92 D95 D97 2.7.6.3 0000287,0003848,0005524,0009396,0016301,0016310,0046654,0046656 P26281 15016362 171 TVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTPPLGPQDQPDYLNAAVALETSLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLFGNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGEMLRQILHTRAFDKLNKW 1rdy A 2.2 BS02 AMP A 1 V17 Q20 G21 A24 T27 E29 M30 T31 K112 Y113 R140 V160 V17 Q20 G21 A24 T27 E29 M30 T31 K112 Y113 R140 V160 D68 D74 E97 E98 D118 L120 D121 E280 D68 D74 E97 E98 D118 L120 D121 E280 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 8844845 339 TDQAAFDTNIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGAAYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK 1rdy B 2.2 BS02 AMP B 1 Q20 G21 A24 G26 T27 E29 M30 T31 K112 Y113 R140 Q20 G21 A24 G26 T27 E29 M30 T31 K112 Y113 R140 D68 D74 E97 E98 D118 L120 D121 E280 D68 D74 E97 E98 D118 L120 D121 E280 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 8844845 339 TDQAAFDTNIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGAAYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK 1rdz A 2.05 BS02 AMP A 1 Q20 G21 A24 T27 G28 E29 M30 K112 Y113 R140 V160 Q20 G21 A24 T27 G28 E29 M30 K112 Y113 R140 V160 D68 D74 E97 E98 D118 L120 D121 E280 D68 D74 E97 E98 D118 L120 D121 E280 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 8844845 339 TDQAAFDTNIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGAAYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK 1rdz B 2.05 BS02 AMP B 1 Q20 G21 A24 T27 G28 E29 M30 K112 Y113 R140 M177 Q20 G21 A24 T27 G28 E29 M30 K112 Y113 R140 M177 D68 D74 E97 E98 D118 L120 D121 E280 D68 D74 E97 E98 D118 L120 D121 E280 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 8844845 339 TDQAAFDTNIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGAAYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK 1ror A 2.0 BS02 AMP A 1 H234 H238 D275 M347 D392 F414 Q443 F446 H83 H87 D124 M196 D241 F263 Q292 F295 3.1.4.53 0004114,0007165,0008081 Q07343 15003452 603 SISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQAPA 1ror B 2.0 BS02 AMP B 1 H234 H238 H274 D275 M347 D392 N395 I410 F414 Q443 F446 H83 H87 H123 D124 M196 D241 N244 I259 F263 Q292 F295 3.1.4.53 0004114,0007165,0008081 Q07343 15003452 703 SISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQAP 1ry2 A 2.3 BS01 AMP A 1 G443 E444 P445 T468 Y469 W470 Q471 T472 D559 I571 R574 G370 E371 P372 T395 Y396 W397 Q398 T399 D486 I498 R501 T320 T472 N580 K675 T247 T399 N507 K590 6.2.1.1 0003987,0005524,0005634,0005737,0005739,0005783,0005829,0006085,0016208,0016874,0016880,0019427,0019654,0044281 Q01574 14769018 720 QDYQRLHKESIEDPAKFFGSKATQFLNWSKPFDKVFIPDPKTGRPSFQNNAWFLNGQLNACYNCVDRHALKTPNKKAIIFEGDEPGQGYSITYKELLEEVCQVAQVLTYSMGVRKGDTVAVYMPMVPEAIITLLAISRIGAIHSVVFAGFSSNSLRDRINDGDSKVVITTDESNRGGKVIETKRIVDDALRETPGVRHVLVYRKTNNPSVAFHAPRDLDWATEKKKYKTYYPCTPVDSEDPLFLLYTSGSTGAPKGVQHSTAGYLLGALLTMRYTFDTHQEDVFFTAGDIGWITGHTYVVYGPLLYGCATLVFEGTPAYPNYSRYWDIIDEHKVTQFYVAPTALRLLKRAGDSYIENHSLKSLRCLGSVGEPIAAEVWEWYSEKIGKNEIPIVDTYWQTESGSHLVTPLAGGVTPMKPGSASFPFFGIDAVVLDPNTGEELNTSHAEGVLAVKAAWPSFARTIWKNHDRYLDTYLNPYPGYYFTGDGAAKDKDGYIWILGRVDDVVNVSGHRLSTAEIEAAIIEDPIVAECAVVGFNDDLTGQAVAAFVVLKLQDIKKHLVFTVRKDIGPFAAPKLIILVDDLPKTRSGKIMRRILRKILANPGIVRHLIDSVKL 1s68 A 1.9 BS01 AMP A 1 K35 I36 N40 R55 E99 F119 V207 K225 K35 I36 N40 R55 E99 F119 V207 K225 6.5.1.3 0003972,0005524,0016874 P32277 14962393 301 MFKKYSSLENHYNSKFIEKLYSLGLTGGEWVAREKIHGTNFSLIIERDKVTCAKRTGPILPAEDFFGYEIILKNYADSIKAVQDIMETSAVVSYQVFGEFAGPGIQKNVDYCDKDFYVFDIIVTTESGDVTYVDDYMMESFCNTFKFKMAPLLGRGKFEELIKLPNDLDSVVQDYNFTVDHAGLVDANKCVWNAEAKGEVFTAEGYVLKPCYPSWLRNGNRVAIKCKNSKFSE 1ses B 2.5 BS01 AMP B 1 R256 E258 M270 R271 V272 F275 E345 T346 H347 T380 A383 R256 E258 M270 R271 V272 F275 E345 T346 H347 T380 A383 R256 R271 E345 S348 R386 R256 R271 E345 S348 R386 6.1.1.11 0000049,0000166,0004812,0004828,0005524,0005737,0006412,0006418,0006434,0016260,0042802,0042803,0070905 P34945 8128224 423 MVDLKRLRQEPEVFHRAIREKGVALDLEALLALDREVQELKKRLQEVQTERNQVAKRVPKAPPEEKEALIARGKALGEEAKRLEEALREKEARLEALLLQVPLPPWPGAPVGGEEANREIKRVGGPPEFSFPPLDHVALMEKNGWWEPRISQVSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVWAIAETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSFGKDVRGLMRVHQFHKVEQYVLTEASLEASDRAFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTLNNTALATPRILAMLLENHQLQDGRVRVPQALIPYMGKEVLEPCG 1son A 2.55 BS01 AMP A 1 N38 G127 T128 T129 Q224 L228 V273 R303 N38 G127 T128 T129 Q224 L228 V273 R303 D13 K16 G40 H41 Q224 D13 K16 G40 H41 Q224 6.3.4.4 0000166,0000287,0004019,0005515,0005525,0005737,0005829,0006164,0006974,0015949,0016020,0016874,0044208,0046040,0046086,0046872,0097216 P0A7D4 8790347 453 GNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA 1t6y A 2.8 BS02 AMP A 1 V7 H15 V18 G99 D101 D127 V128 V135 V6 H14 V17 G98 D100 D126 V127 V134 2.7.1.26,2.7.7.2 0003919,0005524,0006747,0006771,0008531,0009231,0009398,0016301,0016310,0016779,0046872 Q9WZW1 295 VVSIGVFDGVHIGHQKVLRTMKEIAFFRKDDSLIYTISYPPEYFLPDFPGLLMTVESRVEMLSRYARTVVLDFFRIKDLTPEGFVERYLSGVSAVVVGRDFRFGKNASGNASFLRKKGVEVYEIEDVVVQGKRVSSSLIRNLVQEGRVEEIPAYLGRYFEIEGIVHKFPTANIDRGNEKLVDLKRGVYLVRVHLPDGKKKFGVMNVGFRRNVKYEVYILDFEGDLYGQRLKLEVLKFMRDEKKEELKAAIDQDVKSARNMIDDIINSK 1t6y B 2.8 BS02 AMP B 1 V307 H315 V318 V398 G399 D427 V428 V435 V6 H14 V17 V97 G98 D126 V127 V134 2.7.1.26,2.7.7.2 0003919,0005524,0006747,0006771,0008531,0009231,0009398,0016301,0016310,0016779,0046872 Q9WZW1 595 VVSIGVFDGVHIGHQKVLRTMKEIAFFRKDDSLIYTISYPPEYFLPDFPGLLMTVESRVEMLSRYARTVVLDFFRIKDLTPEGFVERYLSGVSAVVVGRDFRFGKNASGNASFLRKKGVEVYEIEDVVVQGKRVSSSLIRNLVQEGRVEEIPAYLGRYFEIEGIVHFPTANIDRGNEKLVDLKRGVYLVRVHLPDGKKKFGVMNVGFNVKYEVYILDFEGDLYGQRLKLEVLKFMRDEKKFDSIEELKAAIDQDVKSARNMIDDIINSKF 1t9g S 2.9 BS01 AMP S 1 A9 V10 K11 C42 C66 V104 L122 G123 Q125 A126 D129 C131 N132 Q133 T134 A6 V7 K8 C39 C63 V101 L119 G120 Q122 A123 D126 C128 N129 Q130 T131 ? 0005515,0005739,0005759,0009055,0009063,0022904,0033539,0045251 P38117 15159392 600 LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPP 1tb5 A 2.15 BS02 AMP A 1 H234 H238 D275 D392 L393 I410 F414 Q443 F446 H72 H76 D113 D230 L231 I248 F252 Q281 F284 3.1.4.53 0004114,0007165,0008081 Q07343 15260978 102 EDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIP 1tb5 B 2.15 BS02 AMP B 1 H234 D275 D392 L393 N395 I410 Q443 F446 H72 D113 D230 L231 N233 I248 Q281 F284 3.1.4.53 0004114,0007165,0008081 Q07343 15260978 101 EDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIP 1tb7 A 1.63 BS02 AMP A 1 H160 D201 D318 L319 N321 I336 Q369 F372 H74 D115 D228 L229 N231 I246 Q279 F282 3.1.4.53 0004114,0007165,0008081 Q08499 15260978 1003 EQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIP 1tb7 B 1.63 BS02 AMP B 1 H160 D201 D318 L319 N321 I336 Q369 F372 H75 D116 D233 L234 N236 I251 Q284 F287 3.1.4.53 0004114,0007165,0008081 Q08499 15260978 1003 TEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIP 1tbw A 2.15 BS01 AMP A 1 N107 A111 M154 N162 G198 F199 N32 A36 M79 N87 G123 F124 ? 0005524,0006457,0016887,0051082,0140662 P41148 15292259 301 FAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTGKTVWDWELMN 1tbw B 2.15 BS01 AMP B 1 N107 M154 N162 G198 F199 N29 M76 N84 G97 F98 ? 0005524,0006457,0016887,0051082,0140662 P41148 15292259 601 QAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKGKTVWDWELMN 1tuu B 2.5 BS01 AMP B 1 D283 R285 G331 I332 N335 S336 D283 R285 G331 I332 N335 S336 N7 R91 H180 R241 E384 N7 R91 H180 R241 E384 2.7.2.1 0000287,0005524,0005737,0006082,0006083,0006085,0008776,0016301,0016310,0016774,0046872 P38502 15647264 2853 MKVLVINAGSSSLKYQLIDMTNESALAVGLCERIGIDNSIITQKKFDGKKLEKLTDLPTHKDALEEVVKALTDDEFGVIKDMGEINAVGHRVVHGGEKFTTSALYDEGVEKAIKDCFELAPLHNPPNMMGISACAEIMPGTPMVIVFDTAFHQTMPPYAYMYALPYDLYEKHGVRKYGFHGTSHKYVAERAALMLGKPAEETKIITCHLGNGSSITAVEGGKSVETSMGFTPLEGLAMGTRCGSIDPAIVPFLMEKEGLTTREIDTLMNKKSGVLGVSGLSNDFRDLDEAASKGNRKAELALEIFAYKVKKFIGEYSAVLNGADAVVFTAGIGENSASIRKRILTGLDGIGIKIDDEKNKIRGQEIDISTPDAKVRVFVIPTNEELAIARETKEIVET 1u9z A 2.8 BS02 AMP B 1 R92 Q93 F97 H125 R92 Q93 F97 H125 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q58761 16288921 5302 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQNDAIVETILLCDALRDEGVKKITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNIVDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLNDPIVLAPDKGALEFAKTASKILNAEYDYLEIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLSEVSKVSVAEVIVDLL 1u9z A 2.8 BS03 AMP B 2 F32 D34 E36 F32 D34 E36 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q58761 16288921 6302 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQNDAIVETILLCDALRDEGVKKITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNIVDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLNDPIVLAPDKGALEFAKTASKILNAEYDYLEIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLSEVSKVSVAEVIVDLL 1u9z B 2.8 BS02 AMP B 1 F32 D34 E36 F32 D34 E36 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q58761 16288921 5302 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQNDAIVETILLCDALRDEGVKKITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNIVDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLNDPIVLAPDKGALEFAKTASKILNAEYDYLEIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLSEVSKVSVAEVIVDLL 1u9z B 2.8 BS03 AMP B 2 R92 Q93 F97 H125 R92 Q93 F97 H125 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q58761 16288921 6302 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQNDAIVETILLCDALRDEGVKKITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNIVDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLNDPIVLAPDKGALEFAKTASKILNAEYDYLEIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLSEVSKVSVAEVIVDLL 1u9z C 2.8 BS02 AMP C 1 F32 D34 E36 F32 D34 E36 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q58761 16288921 8302 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQNDAIVETILLCDALRDEGVKKITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNIVDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLNDPIVLAPDKGALEFAKTASKILNAEYDYLEIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLSEVSKVSVAEVIVDLL 1u9z C 2.8 BS03 AMP D 1 R92 Q93 F97 H125 R92 Q93 F97 H125 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q58761 16288921 7302 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQNDAIVETILLCDALRDEGVKKITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNIVDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLNDPIVLAPDKGALEFAKTASKILNAEYDYLEIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLSEVSKVSVAEVIVDLL 1u9z D 2.8 BS01 AMP C 1 R92 Q93 F97 H125 R92 Q93 F97 H125 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q58761 16288921 8302 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQNDAIVETILLCDALRDEGVKKITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNIVDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLNDPIVLAPDKGALEFAKTASKILNAEYDYLEIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLSEVSKVSVAEVIVDLL 1u9z D 2.8 BS03 AMP D 1 F32 D34 E36 F32 D34 E36 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q58761 16288921 7302 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQNDAIVETILLCDALRDEGVKKITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNIVDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLNDPIVLAPDKGALEFAKTASKILNAEYDYLEIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLSEVSKVSVAEVIVDLL 1ua4 A 1.9 BS03 AMP A 1 N292 H342 T343 Y344 I428 V429 P432 I438 G439 N291 H341 T342 Y343 I427 V428 P431 I437 G438 2.7.1.-,2.7.1.147 0000287,0004340,0005737,0005975,0006006,0006096,0016301,0016310,0016773,0043843,0046872,0051156 Ki~0.06mM -logKd/Ki=4.22, Ki=0.06mM Q9V2Z6 12909015 1456 PTWEELYKNAIEKAIKSVPKVKGVLLGYNTNIDAIKYLDSKDLEERIIKAGKEEVIKYSEELPDKINTVSQLLGSILWSIRRGKAAELFVESCPVRFYMKRWGWNELRMGGQAGIMANLLGGVYGVPVIVHVPQLSRLQANLFLDGPIYVPTLENGEVKLIHPKEFSGDEENCIHYIYEFPRGFRVFEFEAPRENRFIGSADDYNTTLFIREEFRESFSEVIKNVQLAILSGLQALTKENYKEPFEIVKSNLEVLNEREIPVHLEFAFTPDEKVREEILNVLGMFYSVGLNEVELASIMEILGEKKLAKELLAHDPVDPIAVTEAMLKLAKKTGVKRIHFHTYGYYLALTEYKGEHVRDALLFAALAAAAKAMKGNITSLEEIREATSVPVNEKATQVEEKLRAEYGIKEGIGEVEGYQIAFIPTKIVAKPKSTVGIGDTISSSAFIGEFSFTL 1ukz A 1.9 BS02 AMP A 1 L51 R52 I70 Q74 I75 V76 T81 G104 R107 Q111 R148 L43 R44 I62 Q66 I67 V68 T73 G96 R99 Q103 R140 K29 R107 R142 R148 R159 K21 R99 R134 R140 R151 2.7.4.14 0004017,0004127,0005524,0005634,0005737,0006139,0006207,0006221,0006225,0009041,0016301,0016310,0019205,0033862,0046705,0046940,0072528 P15700 7877173 206 PAFSPDQVSVIFVLGGPGAGKGTQCEKLVKDYSFVHLSAGDLLRAEQGRAGSQYGELIKNCIKEGQIVPQEITLALLRNAISDNVKANKHKFLIDGFPRKMDQAISFERDIVESKFILFFDCPEDIMLERLLERGKTSGRSDDNIESIKKRFNTFKETSMPVIEYFETKSKVVRVRCDRSVEDVYKDVQDAIRDSL 1uuy A 1.45 BS01 AMP A 1 R25 S26 G139 R23 S24 G137 2.10.1.1,2.7.7.75 0006777 Q39054 15306815 1165 GPEYKVAILTVSDTVSAGAGPDRSGPRAVSVVDSSSEKLGGAKVVATAVVPDEVERIKDILQKWSDVDEMDLILTLGGTGFTPRDVTPEATKKVIERETPGLLFVMMQESLKITPFAMLARSAAGIRGSTLIINMPGNPNAVAECMEALLPALKHALKQIK 1uxn A 2.3 BS01 AMP A 1 R72 R79 I133 G134 R154 R155 E156 Y184 R70 R77 I131 G132 R152 R153 E154 Y182 N168 K191 E263 C297 E395 E473 N166 K189 E261 C295 E393 E471 1.2.1.90 0000166,0008886,0008911,0016491,0016620,0043878,0050661,0051287 O57693 15288789 1502 AGLLEGVIKEKGGVPVYPSYLAGEWGGSGQEIEVKSPIDLATIAKVISPSREEVERTLDVLFKRGRWSARDMPGTERLAVLRKAADIIERNLDVFAEVLVMNAGKPKSAAVGEVKAAVDRLRLAELDLKKIGGDYIPGDWTYDTLETEGLVRREPLGVVAAITPFNYPLFDAVNKITYSFIYGNAVVVKPSISDPLPAAMAVKALLDAGFPPDAIALLNLPGKEAEKIVADDRVAAVSFTGSTEVGERVVKVGGVKQYVMELGGGDPAIVLEDADLDLAADKIARGIYSYAGQRCDAIKLVLAERPVYGKLVEEVAKRLSSLRVGDPRDPTVDVGPLISPSAVDEMMAAIEDAVEKGGRVLAGGRRLGPTYVQPTFVEAPADRVKDMVLYKREVFAPVALAVEVKDLDQAIELANGRPYGLDAAVFGRDVVKIRRAVRLLEVGAIYINDMPRHGIGYYPFGGRKKSGVFREGIGYAVEAVTAYKTIVFNYKGKGVWKYE 1uxp A 2.55 BS01 AMP A 1 R72 R79 I133 G134 R154 R155 R70 R77 I131 G132 R152 R153 N168 K191 E263 C297 E395 E473 N166 K189 E261 C295 E393 E471 1.2.1.90 0000166,0008886,0008911,0016491,0016620,0043878,0050661,0051287 O57693 15288789 1502 AGLLEGVIKEKGGVPVYPSYLAGEWGGSGQEIEVKSPIDLATIAKVISPSREEVERTLDVLFKRGRWSARDMPGTERLAVLRKAADIIERNLDVFAEVLVMNAGKPKSAAVGEVKAAVDRLRLAELDLKKIGGDYIPGDWTYDTLETEGLVRREPLGVVAAITPFNYPLFDAVNKITYSFIYGNAVVVKPSISDPLPAAMAVKALLDAGFPPDAIALLNLPGKEAEKIVADDRVAAVSFTGSTEVGERVVKVGGVKQYVMELGGGDPAIVLEDADLDLAADKIARGIYSYAGQRCDAIKLVLAERPVYGKLVEEVAKRLSSLRVGDPRDPTVDVGPLISPSAVDEMMAAIEDAVEKGGRVLAGGRRLGPTYVQPTFVEAPADRVKDMVLYKREVFAPVALAVEVKDLDQAIELANGRPYGLDAAVFGRDVVKIRRAVRLLEVGAIYINDMPRHGIGYYPFGGRKKSGVFREGIGYAVEAVTAYKTIVFNYKGKGVWKYE 1uxu A 2.25 BS02 AMP A 1 R72 R79 I133 G134 R154 R155 R70 R77 I131 G132 R152 R153 N168 K191 E263 C297 E395 E473 N166 K189 E261 C295 E393 E471 1.2.1.90 0000166,0008886,0008911,0016491,0016620,0043878,0050661,0051287 O57693 15288789 503 AGLLEGVIKEKGGVPVYPSYLAGEWGGSGQEIEVKSPIDLATIAKVISPSREEVERTLDVLFKRGRWSARDMPGTERLAVLRKAADIIERNLDVFAEVLVMNAGKPKSAAVGEVKAAVDRLRLAELDLKKIGGDYIPGDWTYDTLETEGLVRREPLGVVAAITPFNYPLFDAVNKITYSFIYGNAVVVKPSISDPLPAAMAVKALLDAGFPPDAIALLNLPGKEAEKIVADDRVAAVSFTGSTEVGERVVKVGGVKQYVMELGGGDPAIVLEDADLDLAADKIARGIYSYAGQRCDAIKLVLAERPVYGKLVEEVAKRLSSLRVGDPRDPTVDVGPLISPSAVDEMMAAIEDAVEKGGRVLAGGRRLGPTYVQPTFVEAPADRVKDMVLYKREVFAPVALAVEVKDLDQAIELANGRPYGLDAAVFGRDVVKIRRAVRLLEVGAIYINDMPRHGIGYYPFGGRKKSGVFREGIGYAVEAVTAYKTIVFNYKGKGVWKYE 1uxv A 2.35 BS02 AMP A 1 R72 K132 I133 G134 R154 R155 R70 K130 I131 G132 R152 R153 N168 K191 E263 C297 E395 E473 N166 K189 E261 C295 E393 E471 1.2.1.90 0000166,0008886,0008911,0016491,0016620,0043878,0050661,0051287 O57693 15288789 1503 AGLLEGVIKEKGGVPVYPSYLAGEWGGSGQEIEVKSPIDLATIAKVISPSREEVERTLDVLFKRGRWSARDMPGTERLAVLRKAADIIERNLDVFAEVLVMNAGKPKSAAVGEVKAAVDRLRLAELDLKKIGGDYIPGDWTYDTLETEGLVRREPLGVVAAITPFNYPLFDAVNKITYSFIYGNAVVVKPSISDPLPAAMAVKALLDAGFPPDAIALLNLPGKEAEKIVADDRVAAVSFTGSTEVGERVVKVGGVKQYVMELGGGDPAIVLEDADLDLAADKIARGIYSYAGQRCDAIKLVLAERPVYGKLVEEVAKRLSSLRVGDPRDPTVDVGPLISPSAVDEMMAAIEDAVEKGGRVLAGGRRLGPTYVQPTLVEAPADRVKDMVLYKREVFAPVALAVEVKDLDQAIELANGRPYGLDAAVFGRDVVKIRRAVRLLEVGAIYINDMPRHGIGYYPFGGRKKSGVFREGIGYAVEAVTAYKTIVFNYKGKGVWKYE 1v26 A 2.5 BS02 AMP A 1 G302 S303 A304 G323 Y324 G325 L326 T327 D418 K435 K439 W444 G295 S296 A297 G316 Y317 G318 L319 T320 D411 K428 K432 W437 T184 H204 H230 T327 E328 K439 W444 T177 H197 H223 T320 E321 K432 W437 6.2.1.3 0000287,0001676,0004467,0005524,0006631,0016874,0042802,0042803,0046872 Q5SKN9 15145952 1002 AFPSTMMDEELNLWDFLERAAALFGRKEVVSRLHTGEVHRTTYAEVYQRARRLMGGLRALGVGVGDRVATLGFNHFRHLEAYFAVPGMGAVLHTANPRLSPKEIAYILNHAEDKVLLFDPNLLPLVEAIRGELKTVQHFVVMDEKAPEGYLAYEEALGEEADPVRVPERAACGMAYTTGTTGLPKGVVYSHRALVLHSLAASLVDGTALSEKDVVLPVVPMFHVNAWCLPYAATLVGAKQVLPGPRLDPASLVELFDGEGVTFTAGVPTVWLALADYLESTGHRLKTLRRLVVGGSAAPRSLIARFERMGVEVRQGYGLTETSPVVVQNFVKSHLESLSEEEKLTLKAKTGLPIPLVRLRVADEEGRPVPKDGKALGEVQLKGPWITGGYYGNEEATRSALTPDGFFRTGDIAVWDEEGYVEIKDRLKDLIKSGGEWISSVDLENAAVVAIPHPKWQERPLAVVGFAKWQLPDAYLKRALREQYKNYYG 1v26 B 2.5 BS02 AMP B 1 G302 S303 A304 G323 Y324 G325 L326 T327 D418 K435 K439 W444 G295 S296 A297 G316 Y317 G318 L319 T320 D411 K428 K432 W437 T184 H204 H230 T327 E328 K439 W444 T177 H197 H223 T320 E321 K432 W437 6.2.1.3 0000287,0001676,0004467,0005524,0006631,0016874,0042802,0042803,0046872 Q5SKN9 15145952 2002 AFPSTMMDEELNLWDFLERAAALFGRKEVVSRLHTGEVHRTTYAEVYQRARRLMGGLRALGVGVGDRVATLGFNHFRHLEAYFAVPGMGAVLHTANPRLSPKEIAYILNHAEDKVLLFDPNLLPLVEAIRGELKTVQHFVVMDEKAPEGYLAYEEALGEEADPVRVPERAACGMAYTTGTTGLPKGVVYSHRALVLHSLAASLVDGTALSEKDVVLPVVPMFHVNAWCLPYAATLVGAKQVLPGPRLDPASLVELFDGEGVTFTAGVPTVWLALADYLESTGHRLKTLRRLVVGGSAAPRSLIARFERMGVEVRQGYGLTETSPVVVQNFVKSHLESLSEEEKLTLKAKTGLPIPLVRLRVADEEGRPVPKDGKALGEVQLKGPWITGGYYGNEEATRSALTPDGFFRTGDIAVWDEEGYVEIKDRLKDLIKSGGEWISSVDLENAAAVVAIPHPKWQERPLAVTPEELNEHLLKAGFAKWQLPDAYVFAEEIPRTRALREQYKNYYGGA 1v9p A 2.9 BS02 AMP A 1 E116 K118 Y226 K315 E116 K118 Y226 K315 E116 K118 D120 Y226 K315 C409 C412 C425 C430 E116 K118 D120 Y226 K315 C409 C412 C425 C430 6.5.1.2 0003677,0003911,0006260,0006281 Q9ZHI0 10698952 700 MTREEARRRINELRDLIRYHNYRYYVLADPEISDAEYDRLLRELKELEERFPEFKSPDSPTEQVGARPLEPTFRPVRHPTRMYSLDNAFTYEEVLAFEERLERALGRKRPFLYTVEHKVDGLSVNLYYEEGVLVFGATRGDGEVGEEVTQNLLTIPTIPRRLKGVPDRLEVRGEVYMPIEAFLRLNEELEERGEKVFKNPRNAAAGSLRQKDPRVTAKRGLRATFYALGLGLEESGLKSQYELLLWLKEKGFPVEHGYEKALGAEGVEEVYRRFLAQRHALPFEADGVVVKLDDLALWRELGYTARAPRFALAYKFPAEEKETRLLDVVFQVGRTGRVTPVGVLEPVFIEGSEVSRVTLHNESYIEELDIRIGDWVLVHKAGGVIPEVLRVLKERRTGEERPIRWPETCPECGHRLVKEGKVHRCPNPLCPAKRFEAIRHYASRKAMDIEGLGEKLIERLLEKGLVRDVADLYHLRKEDLLGLERMGEKSAQNLLRQIEESKHRGLERLLYALGLPGVGEVLARNLARRFGTMDRLLEASLEELLEVEEVGELTARAILETLKDPAFRDLVRRLKEAGVSMESK 1v9p B 2.9 BS02 AMP B 1 E2116 K2118 V2119 E2174 Y2226 K2315 E116 K118 V119 E174 Y226 K315 E2116 K2118 D2120 Y2226 K2315 C2409 C2412 C2425 C2430 E116 K118 D120 Y226 K315 C409 C412 C425 C430 6.5.1.2 0003677,0003911,0006260,0006281 Q9ZHI0 10698952 2700 MTREEARRRINELRDLIRYHNYRYYVLADPEISDAEYDRLLRELKELEERFPEFKSPDSPTEQVGARPLEPTFRPVRHPTRMYSLDNAFTYEEVLAFEERLERALGRKRPFLYTVEHKVDGLSVNLYYEEGVLVFGATRGDGEVGEEVTQNLLTIPTIPRRLKGVPDRLEVRGEVYMPIEAFLRLNEELEERGEKVFKNPRNAAAGSLRQKDPRVTAKRGLRATFYALGLGLEESGLKSQYELLLWLKEKGFPVEHGYEKALGAEGVEEVYRRFLAQRHALPFEADGVVVKLDDLALWRELGYTARAPRFALAYKFPAEEKETRLLDVVFQVGRTGRVTPVGVLEPVFIEGSEVSRVTLHNESYIEELDIRIGDWVLVHKAGGVIPEVLRVLKERRTGEERPIRWPETCPECGHRLVKEGKVHRCPNPLCPAKRFEAIRHYASRKAMDIEGLGEKLIERLLEKGLVRDVADLYHLRKEDLLGLERMGEKSAQNLLRQIEESKHRGLERLLYALGLPGVGEVLARNLARRFGTMDRLLEASLEELLEVEEVGELTARAILETLKDPAFRDLVRRLKEAGVSMESK 1vd1 A 1.8 BS01 AMP A 1 W42 N44 W50 H92 E93 K96 H97 W41 N43 W49 H91 E92 K95 H96 H39 W42 W50 E93 K96 H97 H38 W41 W49 E92 K95 H96 3.1.27.1 0003723,0033897 Q9SSV1 295 QDFDFFYFVQQWPASYCDTRRSCCYPTTGKPDEDFSIHGLWPNYENGKWPQNCDRESSLDESEISDLISTMEKNWPSLACPSSDGVRFWSHEWLKHGTCSALGERAYFQAALDFRKKSNLLENLKNAEITPRNGEHYTLESIKKAIEEGVGHSPYIECNVDTQGNHQIYQVYLCVDKTATDFIDCPIFPHGRGCGSKIEFPPF 1vd1 A 1.8 BS02 AMP A 2 Q12 Y17 H39 S78 L79 A80 Y170 Q11 Y16 H38 S77 L78 A79 Y169 H39 W42 W50 E93 K96 H97 H38 W41 W49 E92 K95 H96 3.1.27.1 0003723,0033897 Q9SSV1 296 QDFDFFYFVQQWPASYCDTRRSCCYPTTGKPDEDFSIHGLWPNYENGKWPQNCDRESSLDESEISDLISTMEKNWPSLACPSSDGVRFWSHEWLKHGTCSALGERAYFQAALDFRKKSNLLENLKNAEITPRNGEHYTLESIKKAIEEGVGHSPYIECNVDTQGNHQIYQVYLCVDKTATDFIDCPIFPHGRGCGSKIEFPPF 1w0h A 1.59 BS03 AMP A 1 E136 A137 C139 F185 L189 F238 H293 E14 A15 C17 F63 L67 F116 H171 D134 E136 D234 H293 D298 D12 E14 D112 H171 D176 3.1.-.- 0000175,0003676 Q8IV48 15451662 1002 ADSYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDWMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHCGLDDSKNIARIAVRMLQDGCELRINEKM 1wxe A 1.9 BS02 AMP A 1 G46 I47 S48 L83 R142 T160 D176 G45 I46 S47 L82 R141 T159 D175 D52 E165 D51 E164 6.3.1.5 0000287,0003952,0004359,0005515,0005524,0005737,0005829,0006974,0008795,0009435,0016874,0034355,0034628,0042803,0046872 P18843 15699042 400 TLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRLETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALACPEHLYKEVALGVTYDNIDDYLEGKNVPQQVARTIENWYLKTEHKRRPPITVFDDFWKK 1wxe A 1.9 BS03 AMP A 2 Y33 Y147 V156 D180 Y32 Y146 V155 D179 D52 E165 D51 E164 6.3.1.5 0000287,0003952,0004359,0005515,0005524,0005737,0005829,0006974,0008795,0009435,0016874,0034355,0034628,0042803,0046872 P18843 15699042 500 TLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRLETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALACPEHLYKEVALGVTYDNIDDYLEGKNVPQQVARTIENWYLKTEHKRRPPITVFDDFWKK 1wxi A 1.7 BS02 AMP A 1 T172 K173 H260 K261 T171 K172 H246 K247 D52 E165 D51 E164 6.3.1.5 0000287,0003952,0004359,0005515,0005524,0005737,0005829,0006974,0008795,0009435,0016874,0034355,0034628,0042803,0046872 P18843 15699042 300 TLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRLETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALACPEHLYKKADEVALGVTYDNIDDYLEGKNVPQQVARTIENWYLKTEHKRRPPITVFDDFWKK 1wxi A 1.7 BS03 AMP A 2 G46 I47 S48 L83 Q88 R142 T160 D176 G45 I46 S47 L82 Q87 R141 T159 D175 D52 E165 D51 E164 6.3.1.5 0000287,0003952,0004359,0005515,0005524,0005737,0005829,0006974,0008795,0009435,0016874,0034355,0034628,0042803,0046872 P18843 15699042 400 TLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRLETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALACPEHLYKKADEVALGVTYDNIDDYLEGKNVPQQVARTIENWYLKTEHKRRPPITVFDDFWKK 1x9n A 3.0 BS04 AMP C 1 Y567 K568 Y569 R573 E621 F660 M723 K725 W742 Y298 K299 Y300 R304 E352 F391 M454 K456 W473 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 15565146 100 DPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAEMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 1xqs C 2.9 BS01 AMP C 1 E268 K271 R272 S275 G339 S340 R342 E77 K80 R81 S84 G148 S149 R151 D199 D8 ? 0005524,0140662 P0DMV8 15694338 401 ERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNG 1xqs D 2.9 BS01 AMP D 1 G202 E268 K271 R272 S275 G338 G339 S340 G11 E77 K80 R81 S84 G147 G148 S149 D199 D8 ? 0005524,0140662 P0DMV8 15694338 402 ERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNG 1y1p A 1.6 BS02 AMP A 1 G19 N21 G22 F23 R44 M72 S93 S222 G18 N20 G21 F22 R43 M71 S92 S221 1.1.1.2 0008106,0008150,0016491,0016616 Q9UUN9 16095619 1002 AKIDNAVLPEGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVEDMLKQGAYDEVIKGAAGVAHIASVVSFSNKYDEVVTPAIGGTLNALRAAAATPSVKRFVLTSSTVSALIPKPNVEGIYLDEKSWNLESIDKAKTLPESDPQKSLWVYAASKTEAELAAWKFMDENKPHFTLNAVLPNYTIGTIFDPETQSGSTSGWMMSLFNGEVSPALALMPPQYYVSAVDIGLLHLGCLVLPQIERRRVYGTAGTFDWNTVLATFRKLYPSKTFPADFPDQGQDLSKFDTAPSLEILKSLGRPGWRSIEESIKDLVGSETA 1y1p B 1.6 BS02 AMP B 1 N21 G22 F23 R44 M72 S93 V94 N20 G21 F22 R43 M71 S92 V93 1.1.1.2 0008106,0008150,0016491,0016616 Q9UUN9 16095619 2002 AKIDNAVLPEGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVEDMLKQGAYDEVIKGAAGVAHIASVVSFSNKYDEVVTPAIGGTLNALRAAAATPSVKRFVLTSSTVSALIPKPNVEGIYLDEKSWNLESIDKAKTLPESDPQKSLWVYAASKTEAELAAWKFMDENKPHFTLNAVLPNYTIGTIFDPETQSGSTSGWMMSLFNGEVSPALALMPPQYYVSAVDIGLLHLGCLVLPQIERRRVYGTAGTFDWNTVLATFRKLYPSKTFPADFPDQGQDLSKFDTAPSLEILKSLGRPGWRSIEESIKDLVGSETA 1yxu A 2.24 BS01 AMP A 1 L44 F49 A65 K67 L120 N172 L174 I185 D186 L12 F17 A33 K35 L88 N140 L142 I153 D154 D167 K169 N172 D186 L193 T204 D135 K137 N140 D154 L161 T172 2.7.11.1 0004672,0004674,0005515,0005524,0005634,0005654,0005730,0005737,0005829,0005886,0006338,0006468,0006915,0008134,0016310,0022898,0030145,0043024,0043066,0043433,0044024,0045824,0045893,0046777,0046872,0050821,0060045,0070561,0071346,0090336,0106310,1902033,1904263,1905062,1990748 P11309 15808862 550 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 1yxu B 2.24 BS01 AMP B 1 L44 F49 A65 K67 I104 L120 I185 D186 L12 F17 A33 K35 I72 L88 I153 D154 D167 K169 N172 D186 L193 T204 D135 K137 N140 D154 L161 T172 2.7.11.1 0004672,0004674,0005515,0005524,0005634,0005654,0005730,0005737,0005829,0005886,0006338,0006468,0006915,0008134,0016310,0022898,0030145,0043024,0043066,0043433,0044024,0045824,0045893,0046777,0046872,0050821,0060045,0070561,0071346,0090336,0106310,1902033,1904263,1905062,1990748 P11309 15808862 650 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 1yxu C 2.24 BS01 AMP C 1 L44 F49 A65 K67 I104 L120 R122 L174 I185 D186 L11 F16 A32 K34 I71 L87 R89 L141 I152 D153 D167 K169 N172 D186 L193 T204 D134 K136 N139 D153 L160 T171 2.7.11.1 0004672,0004674,0005515,0005524,0005634,0005654,0005730,0005737,0005829,0005886,0006338,0006468,0006915,0008134,0016310,0022898,0030145,0043024,0043066,0043433,0044024,0045824,0045893,0046777,0046872,0050821,0060045,0070561,0071346,0090336,0106310,1902033,1904263,1905062,1990748 P11309 15808862 750 LESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 1yxu D 2.24 BS01 AMP D 1 F49 V52 K67 I104 L120 E121 L174 I185 D186 F17 V20 K35 I72 L88 E89 L142 I153 D154 D167 K169 N172 D186 L193 T204 D135 K137 N140 D154 L161 T172 2.7.11.1 0004672,0004674,0005515,0005524,0005634,0005654,0005730,0005737,0005829,0005886,0006338,0006468,0006915,0008134,0016310,0022898,0030145,0043024,0043066,0043433,0044024,0045824,0045893,0046777,0046872,0050821,0060045,0070561,0071346,0090336,0106310,1902033,1904263,1905062,1990748 P11309 15808862 850 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 1yyz A 1.85 BS04 AMP A 1 V17 E20 G21 A24 T27 E29 M30 Y113 R140 M177 V8 E11 G12 A15 T18 E20 M21 Y104 R131 M168 D68 D74 E97 E98 D118 L120 D121 E280 D59 D65 E88 E89 D109 L111 D112 E271 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 Kd=2.4uM IC50=1300nM P00636 15767255 435 IVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGILHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 1yz0 A 2.07 BS03 AMP A 1 V17 E20 G21 A24 T27 E29 M30 Y113 R140 M177 V9 E12 G13 A16 T19 E21 M22 Y105 R132 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 Kd=2.4uM IC50=1300nM P00636 15767255 1844 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGILHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK 1yz0 B 2.07 BS03 AMP B 1 V17 E20 G21 A24 G26 T27 E29 M30 K112 Y113 R140 M177 V9 E12 G13 A16 G18 T19 E21 M22 K104 Y105 R132 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 Kd=2.4uM IC50=1300nM P00636 15767255 1841 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGILHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK 1z6s A 1.5 BS01 AMP A 1 Q11 H12 N67 Q69 N71 A109 H119 Q11 H12 N67 Q69 N71 A109 H119 H12 K41 H119 F120 D121 H12 K41 H119 F120 D121 4.6.1.18 0003676,0004519,0004522,0004540,0005515,0005576,0016829,0050830 Ki=46uM -logKd/Ki=4.34, Ki=46uM P61823 16045769 1101 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 1z6s B 1.5 BS01 AMP B 1 H12 C65 N67 Q69 N71 A109 H119 F120 H12 C65 N67 Q69 N71 A109 H119 F120 H12 K41 H119 F120 D121 H12 K41 H119 F120 D121 4.6.1.18 0003676,0004519,0004522,0004540,0005515,0005576,0016829,0050830 Ki=46uM P61823 16045769 1102 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 1z84 A 1.83 BS03 AMP A 1 F65 N94 L95 Y96 N173 A180 S181 M182 H186 Q188 F33 N62 L63 Y64 N133 A140 S141 M142 H146 Q148 C63 C66 H133 N173 S181 H184 H186 Q188 C31 C34 H93 N133 S141 H144 H146 Q148 2.7.7.- 0005975,0006006,0006012,0008108,0008270,0016779,0017103,0043531,0046872,0047345,0080040 Q9FK51 16519510 601 SPELRKDPVTNRWVIFSPRPTDFKSKSPSSCPFCIGREQECAPELFRVPDHDPNWKLRVIENLYPALSRNLETQSRTIVGFGFHDVVIESPVHSIQLSDIDPVGIGDILIAYKKRINQIAQHDSINYIQVFKNQGASAGASMSHSHSQMMALPVVPPTVSSRLDGTKDYFEETGKCCLCEAKSKHFVIDESSHFVSVAPFAATYPFEIWIIPKDHSSHFHHLDDVKAVDLGGLLKLMLQKIAKQLNDPPYNYMIHTSPLKVTESQLPYTHWFLQIVPQLSGVGGFEIGTGCYINPVFPEDVAKVMREVSLT 1z84 B 1.83 BS03 AMP B 1 F65 N94 L95 Y96 N173 A180 S181 M182 H186 Q188 F28 N57 L58 Y59 N128 A135 S136 M137 H141 Q143 C63 C66 H133 N173 S181 H184 H186 Q188 C26 C29 H88 N128 S136 H139 H141 Q143 2.7.7.- 0005975,0006006,0006012,0008108,0008270,0016779,0017103,0043531,0046872,0047345,0080040 Q9FK51 16519510 602 QSPELRKDPVTNRWVIFSPTDFKSSCPFCIGREQECAPELFRVPDHDPNWKLRVIENLYPALSRNLETQSRTIVGFGFHDVVIESPVHSIQLSDIDPVGIGDILIAYKKRINQIAQHDSINYIQVFKNQGASAGASMSHSHSQMMALPVVPPTVSSRLDGTKDYFEETGKCCLCEAKSKHFVIDESSHFVSVAPFAATYPFEIWIIPKDHSSHFHHLDDVKAVDLGGLLKLMLQKIAKQLNDPPYNYMIHTSPLKVTESQLPYTHWFLQIVPQLSGVGGFEIGTGCYINPVFPEDVAKVMREVSL 1z8d A 2.3 BS02 AMP A 1 W67 Q71 Y75 R309 R310 F316 G317 C318 W63 Q67 Y71 R294 R295 F301 G302 C303 H377 K568 R569 K574 T676 K680 H362 K553 R554 K559 T661 K665 2.4.1.1 0000166,0004645,0005515,0005737,0005829,0005975,0005977,0005980,0008184,0016757,0030170,0070062,0102250,0102499 P11217 16523484 900 RPLSDQEKRKQISVRGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGHVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDLERMDWDKAWDVTVRTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEVIAERIGEDFISDLDQLRKLLSFVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIKREPNKFFVPRTVMIGGKAAPGYHMAKMIIRLVTAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDKLDQRGYNAQEYYDRIPELRQVIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEDYIKCQEKVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 1zau A 3.15 BS01 AMP A 1 L92 N94 L122 K123 E184 H236 V298 K300 L85 N87 L115 K116 E177 H229 V291 K293 E121 K123 D125 H236 K324 E114 K116 D118 H229 K317 6.5.1.2 0003911 P9WNV1 15901723 400 QTAPEVLRQWQALAEEVREHQFRYYVRDAPIISDAEFDELLRRLEALEEQHPELRTPDSPTQLVGGAGFATDFEPVDHLERMLSLDNAFTADELAAWAGRIHAEVGDAAHYLCELKIDGVALSLVYREGRLTRASTRGDGRTGEDVTLNARTIADVPERLTPGDDYPVPEVLEVRGEVFFRLDDFQALNASLVEEGKAPFANPRNSAAGSLRQKDPAVTARRRLRMICHGLGHVEGFRPATLHQAYLALRAWGLPVSEHTTLATDLAGVRERIDYWGEHRHEVDHEIDGVVVKVDEVALQRRLGSTSRAPRWAIAYKYPPE 1zbh A 3.0 BS04 AMP A 1 D134 F135 E136 A137 C139 N143 F185 F238 D75 F76 E77 A78 C80 N84 F126 F179 D134 D234 D298 D75 D175 D239 3.1.-.- 0000175,0003676 Q8IV48 1002 DFSDPVYKEIAITNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKESNFADSYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDLMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPNCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFR 1zbh B 3.0 BS02 AMP B 1 D134 E136 A137 C139 N143 F185 L189 F238 D11 E13 A14 C16 N20 F62 L66 F115 D134 D234 D298 D11 D111 D175 3.1.-.- 0000175,0003676 Q8IV48 2002 DSYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDLMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPNCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFR 1zbh C 3.0 BS03 AMP C 1 D134 E136 A137 C139 N143 F185 L189 F238 D11 E13 A14 C16 N20 F62 L66 F115 D134 E136 D234 N293 D298 D11 E13 D111 N170 D175 3.1.-.- 0000175,0003676 Q8IV48 3002 DSYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDLMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPNCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFR 1zbh D 3.0 BS04 AMP D 1 D134 E136 A137 C139 N143 F185 F238 D75 E77 A78 C80 N84 F126 F179 D134 E136 D234 N293 D298 D75 E77 D175 N234 D239 3.1.-.- 0000175,0003676 Q8IV48 4002 DFSDPVYKEIAITNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKESNFADSYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDLMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPNCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFR 1zbu A 2.998 BS03 AMP A 1 E136 A137 C139 N143 F185 H293 E12 A13 C15 N19 F61 H169 D134 E136 D234 H293 D298 D10 E12 D110 H169 D174 3.1.-.- 0000175,0000460,0000467,0003676,0003723,0004527,0005515,0005634,0005730,0005737,0006364,0008408,0019843,0031047,0031125,0043022,0046872,0071044,0071204,0071207 Q8IV48 1002 SYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDLMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFRK 1zbu B 2.998 BS02 AMP B 1 E136 A137 C139 N143 F185 L189 H293 E91 A92 C94 N98 F140 L144 H248 D134 E136 D234 H293 D298 D89 E91 D189 H248 D253 3.1.-.- 0000175,0000460,0000467,0003676,0003723,0004527,0005515,0005634,0005730,0005737,0006364,0008408,0019843,0031047,0031125,0043022,0046872,0071044,0071204,0071207 Q8IV48 2002 CKFDGQETKGSKFITSSASDYKEIAITNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKESNFADSYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDLMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFRK 1zbu C 2.998 BS03 AMP C 1 E136 A137 C139 N143 F185 F238 H293 E12 A13 C15 N19 F61 F114 H169 D134 E136 D234 H293 D298 D10 E12 D110 H169 D174 3.1.-.- 0000175,0000460,0000467,0003676,0003723,0004527,0005515,0005634,0005730,0005737,0006364,0008408,0019843,0031047,0031125,0043022,0046872,0071044,0071204,0071207 Q8IV48 3002 SYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDLMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFRK 1zbu D 2.998 BS02 AMP D 1 E136 A137 C139 N143 F185 W233 F238 H293 E12 A13 C15 N19 F61 W109 F114 H169 D134 E136 D234 H293 D298 D10 E12 D110 H169 D174 3.1.-.- 0000175,0000460,0000467,0003676,0003723,0004527,0005515,0005634,0005730,0005737,0006364,0008408,0019843,0031047,0031125,0043022,0046872,0071044,0071204,0071207 Q8IV48 4002 SYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDLMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFRK 1zjw A 2.5 BS02 AMP A 1 P33 E34 G42 H43 S46 T230 R260 L261 K270 P26 E27 G35 H36 S39 T223 R253 L254 K263 6.1.1.18 0000166,0004812,0004819,0005524,0005737,0005829,0006412,0006418,0006424,0006425,0043039 P00962 15845536 998 TNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDT 1zn8 A 1.76 BS01 AMP A 1 F26 R27 R67 D127 D128 L129 A131 T132 G133 T135 F24 R25 R65 D125 D126 L127 A129 T130 G131 T133 R67 E104 R65 E102 2.4.2.7 0002055,0003999,0005515,0005576,0005654,0005737,0005829,0006166,0006168,0007625,0016208,0016757,0032263,0032264,0034774,0044209,0046083,0070062 P07741 18399692 1031 DSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 1zn8 B 1.76 BS01 AMP B 1 F26 R27 R67 D127 D128 A131 T132 G133 G134 T135 F25 R26 R66 D126 D127 A130 T131 G132 G133 T134 R67 E104 R66 E103 2.4.2.7 0002055,0003999,0005515,0005576,0005654,0005737,0005829,0006166,0006168,0007625,0016208,0016757,0032263,0032264,0034774,0044209,0046083,0070062 P07741 18399692 1032 ADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 1zn9 B 2.05 BS01 AMP B 1 F26 R27 R67 D127 L129 A131 T132 G133 T135 F25 R26 R66 D126 L128 A130 T131 G132 T134 R67 E104 R66 E103 2.4.2.7 0002055,0003999,0005515,0005576,0005654,0005737,0005829,0006166,0006168,0007625,0016208,0016757,0032263,0032264,0034774,0044209,0046083,0070062 P07741 18399692 1031 ADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 2a1t S 2.8 BS01 AMP S 1 A9 K11 C42 C66 V104 L122 G123 Q125 A126 D129 C131 N132 T134 A7 K9 C40 C64 V102 L120 G121 Q123 A124 D127 C129 N130 T132 ? 0005515,0005739,0005759,0009055,0009063,0022904,0033539,0045251 P38117 15975918 600 ELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVERAIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPTTEDLVAKLK 2a1u B 2.11 BS02 AMP B 1 A9 V10 K11 C42 C66 V104 L122 G123 Q125 A126 D129 C131 N132 Q133 T134 A6 V7 K8 C39 C63 V101 L119 G120 Q122 A123 D126 C128 N129 Q130 T131 ? 0005515,0005739,0005759,0009055,0009063,0022904,0033539,0045251 P38117 15975918 600 LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVERAIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTEDLVAKLKEIGRI 2a7x A 1.7 BS01 AMP A 1 P38 M40 G46 H47 L50 F157 G158 K160 D161 T186 V187 M195 P36 M38 G44 H45 L48 F146 G147 K149 D150 T175 V176 M184 M40 H44 H47 D88 D89 Q92 K160 S196 S197 R198 M38 H42 H45 D77 D78 Q81 K149 S185 S186 R187 6.3.2.1 0000287,0004592,0005515,0005524,0005737,0005829,0015940,0016874,0019482,0030145,0046872 P9WIL5 16460002 501 IPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGSVVVVSIFVNPMQFGAGGDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIG 2a86 A 1.85 BS01 AMP A 1 P38 M40 G46 H47 L50 F157 G158 K160 D161 T186 V187 M195 P36 M38 G44 H45 L48 F155 G156 K158 D159 T184 V185 M193 M40 H44 H47 D88 D89 Q92 K160 S196 S197 R198 M38 H42 H45 D86 D87 Q90 K158 S194 S195 R196 6.3.2.1 0000287,0004592,0005515,0005524,0005737,0005829,0015940,0016874,0019482,0030145,0046872 P9WIL5 16460002 1001 IPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGSVVVVSIFVNPMQFGAGGDLDAYPRTPDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTF 2a86 B 1.85 BS01 AMP B 1 P38 T39 M40 G46 H47 L50 F157 G158 K160 D161 T186 V187 M195 P37 T38 M39 G45 H46 L49 F146 G147 K149 D150 T175 V176 M184 M40 H44 H47 D88 D89 Q92 K160 S196 S197 R198 M39 H43 H46 D77 D78 Q81 K149 S185 S186 R187 6.3.2.1 0000287,0004592,0005515,0005524,0005737,0005829,0015940,0016874,0019482,0030145,0046872 P9WIL5 16460002 1002 AIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGSVVVVSIFVNPMQFRTPDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIG 2ak3 A 1.85 BS02 AMP A 1 S36 L40 I58 K62 L63 I64 M69 R92 Q96 S37 L41 I59 K63 L64 I65 M70 R93 Q97 K18 R92 R126 R159 R170 K19 R93 R127 R160 R171 2.7.4.10 0004017,0005524,0005525,0005737,0005739,0005759,0006139,0006172,0009142,0016301,0016310,0016776,0019205,0043231,0046033,0046039,0046041,0046051,0046899,0046940 P08760 1994037 226 GASARLLRAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLTQYNWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDDRPETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGTETNKIWPHVYAFLQTKLPQRSQETSVTP 2ak3 B 1.85 BS02 AMP B 1 S36 L40 R41 L63 I64 M69 G89 R92 Q96 S37 L41 R42 L64 I65 M70 G90 R93 Q97 K18 R92 R126 R159 R170 K19 R93 R127 R160 R171 2.7.4.10 0004017,0005524,0005525,0005737,0005739,0005759,0006139,0006172,0009142,0016301,0016310,0016776,0019205,0043231,0046033,0046039,0046041,0046051,0046899,0046940 P08760 1994037 226 GASARLLRAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLTQYNWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDDRPETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGTETNKIWPHVYAFLQTKLPQRSQ 2art A 2.4 BS03 AMP A 1 G77 V79 Y80 P132 K135 K145 A163 L165 L173 G77 V79 Y80 P132 K135 K145 A163 L165 L173 6.3.1.20 0005515,0005524,0005737,0009249,0016874,0016979,0017118,0031405,0032991,0036211,0046872 Q9HKT1 16141198 302 MEGRLLLLETPGNTRMSLAYDEAIYRSFQYGDKPILRFYRHDRSVIIGYFQVAEEEVDLDYMKKNGIMLARRYTGGGAVYHDLGDLNFSVVRSSDDMDITSMFRTMNEAVVNSLRILGLDARPGELNDVSIPVNKKTDIMAGEKKIMGAAGAMRKGAKLWHAAMLVHTDLDMLSAVLKVPSTRERVANVTDFVDVSIDEVRNALIRGFSETLHIDFREDTITEKEESLARELFDKKYSTEEWNMGLL 2bwj B 2.3 BS01 AMP B 1 E29 H39 E26 H36 K24 R100 M135 P141 R152 K21 R97 M132 P138 R149 2.7.4.3,2.7.4.6 0004017,0005524,0005737,0006139,0019205,0046034 Q9Y6K8 1201 FMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQMSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIFL 2c38 B 3.1 BS01 AMP B 1 T88 R99 A134 A136 S138 R139 E179 D182 T81 R92 A127 A129 S131 R132 E172 D175 3.1.13.- 0000175,0000177,0000178,0003723,0004527,0005515,0005737,0006401,0016075,0016896 Q9UXC2 16285928 404 ERPKLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKEMHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVELFPRTAIDVFTEILQADAGSRLVSLMAASLALADAGIPMRDLIAGVAVGKADGVIILDLNETEDMWGEADMPIAMMPSLNQVTLFQLNGSMTPDEFRQAFDLAVKGINIIYNLEREALKSKYVEFKEEGV 2c38 F 3.1 BS01 AMP F 1 T88 R99 A136 S138 R139 E179 D182 T81 R92 A129 S131 R132 E172 D175 3.1.13.- 0000175,0000177,0000178,0003723,0004527,0005515,0005737,0006401,0016075,0016896 Q9UXC2 16285928 404 ERPKLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKEMHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVELFPRTAIDVFTEILQADAGSRLVSLMAASLALADAGIPMRDLIAGVAVGKADGVIILDLNETEDMWGEADMPIAMMPSLNQVTLFQLNGSMTPDEFRQAFDLAVKGINIIYNLEREALKSKYVEFKEEGV 2c38 G 3.1 BS01 AMP H 1 Y75 I85 Y75 I85 3.1.13.- 0000177,0000178,0005515,0005737,0006401,0016075,0035925 Q9UXC0 16285928 401 MSSTPSNQNIIPIIKKESIVSLFEKGIRQDGRKLTDYRPLSITLDYAKKADGSALVKLGTTMVLAGTKLEIDKPYEDTPNQGNLIVNVELLPLAYETFEPGPPDENAIELARVVDRSLRDSKALDLTKLVIEPGKSVWTVWLDVYVLDYGGNVLDACTLASVAALYNTKVYKVEQISVNKNEVVGKLPLNYPVVTISVAKVDKYLVVDPDLDEESIMDAKISFSYTPDLKIVGIQKSGKGSMSLQDIDQAENTARSTAVKLLEELKKHLGI 2c38 H 3.1 BS01 AMP H 2 T88 R99 A134 A136 S138 R139 E179 D182 T81 R92 A127 A129 S131 R132 E172 D175 3.1.13.- 0000175,0000177,0000178,0003723,0004527,0005515,0005737,0006401,0016075,0016896 Q9UXC2 16285928 404 ERPKLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKEMHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVELFPRTAIDVFTEILQADAGSRLVSLMAASLALADAGIPMRDLIAGVAVGKADGVIILDLNETEDMWGEADMPIAMMPSLNQVTLFQLNGSMTPDEFRQAFDLAVKGINIIYNLEREALKSKYVEFKEEGV 2c38 I 3.1 BS01 AMP J 1 R112 D115 R112 D115 3.1.13.- 0000177,0000178,0005515,0005737,0006401,0016075,0035925 Q9UXC0 16285928 402 MSSTPSNQNIIPIIKKESIVSLFEKGIRQDGRKLTDYRPLSITLDYAKKADGSALVKLGTTMVLAGTKLEIDKPYEDTPNQGNLIVNVELLPLAYETFEPGPPDENAIELARVVDRSLRDSKALDLTKLVIEPGKSVWTVWLDVYVLDYGGNVLDACTLASVAALYNTKVYKVEQISVNKNEVVGKLPLNYPVVTISVAKVDKYLVVDPDLDEESIMDAKISFSYTPDLKIVGIQKSGKGSMSLQDIDQAENTARSTAVKLLEELKKHLGI 2c38 J 3.1 BS01 AMP J 2 T88 R99 A136 R139 E179 D182 T81 R92 A129 R132 E172 D175 3.1.13.- 0000175,0000177,0000178,0003723,0004527,0005515,0005737,0006401,0016075,0016896 Q9UXC2 16285928 404 ERPKLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKEMHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVELFPRTAIDVFTEILQADAGSRLVSLMAASLALADAGIPMRDLIAGVAVGKADGVIILDLNETEDMWGEADMPIAMMPSLNQVTLFQLNGSMTPDEFRQAFDLAVKGINIIYNLEREALKSKYVEFKEEGV 2c38 N 3.1 BS01 AMP N 1 T88 R99 A136 S138 R139 E179 D182 T81 R92 A129 S131 R132 E172 D175 3.1.13.- 0000175,0000177,0000178,0003723,0004527,0005515,0005737,0006401,0016075,0016896 Q9UXC2 16285928 404 ERPKLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKEMHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVELFPRTAIDVFTEILQADAGSRLVSLMAASLALADAGIPMRDLIAGVAVGKADGVIILDLNETEDMWGEADMPIAMMPSLNQVTLFQLNGSMTPDEFRQAFDLAVKGINIIYNLEREALKSKYVEFKEEGV 2c38 U 3.1 BS01 AMP V 1 Y75 I85 Y75 I85 3.1.13.- 0000177,0000178,0005515,0005737,0006401,0016075,0035925 Q9UXC0 16285928 401 MSSTPSNQNIIPIIKKESIVSLFEKGIRQDGRKLTDYRPLSITLDYAKKADGSALVKLGTTMVLAGTKLEIDKPYEDTPNQGNLIVNVELLPLAYETFEPGPPDENAIELARVVDRSLRDSKALDLTKLVIEPGKSVWTVWLDVYVLDYGGNVLDACTLASVAALYNTKVYKVEQISVNKNEVVGKLPLNYPVVTISVAKVDKYLVVDPDLDEESIMDAKISFSYTPDLKIVGIQKSGKGSMSLQDIDQAENTARSTAVKLLEELKKHLG 2c38 U 3.1 BS02 AMP V 2 R112 D115 R119 R112 D115 R119 3.1.13.- 0000177,0000178,0005515,0005737,0006401,0016075,0035925 Q9UXC0 16285928 402 MSSTPSNQNIIPIIKKESIVSLFEKGIRQDGRKLTDYRPLSITLDYAKKADGSALVKLGTTMVLAGTKLEIDKPYEDTPNQGNLIVNVELLPLAYETFEPGPPDENAIELARVVDRSLRDSKALDLTKLVIEPGKSVWTVWLDVYVLDYGGNVLDACTLASVAALYNTKVYKVEQISVNKNEVVGKLPLNYPVVTISVAKVDKYLVVDPDLDEESIMDAKISFSYTPDLKIVGIQKSGKGSMSLQDIDQAENTARSTAVKLLEELKKHLG 2c38 V 3.1 BS01 AMP V 3 T88 R99 A134 A136 S138 R139 E179 D182 T80 R91 A126 A128 S130 R131 E171 D174 3.1.13.- 0000175,0000177,0000178,0003723,0004527,0005515,0005737,0006401,0016075,0016896 Q9UXC2 16285928 404 RPKLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKEMHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVELFPRTAIDVFTEILQADAGSRLVSLMAASLALADAGIPMRDLIAGVAVGKADGVIILDLNETEDMWGEADMPIAMMPSLNQVTLFQLNGSMTPDEFRQAFDLAVKGINIIYNLEREALKSKYVEFKEEG 2c38 W 3.1 BS01 AMP X 1 Y75 I85 Y75 I85 3.1.13.- 0000177,0000178,0005515,0005737,0006401,0016075,0035925 Q9UXC0 16285928 401 MSSTPSNQNIIPIIKKESIVSLFEKGIRQDGRKLTDYRPLSITLDYAKKADGSALVKLGTTMVLAGTKLEIDKPYEDTPNQGNLIVNVELLPLAYETFEPGPPDENAIELARVVDRSLRDSKALDLTKLVIEPGKSVWTVWLDVYVLDYGGNVLDACTLASVAALYNTKVYKVEQISVNKNEVVGKLPLNYPVVTISVAKVDKYLVVDPDLDEESIMDAKISFSYTPDLKIVGIQKSGKGSMSLQDIDQAENTARSTAVKLLEELKKHLGI 2c38 W 3.1 BS02 AMP X 2 R112 D115 R119 R112 D115 R119 3.1.13.- 0000177,0000178,0005515,0005737,0006401,0016075,0035925 Q9UXC0 16285928 402 MSSTPSNQNIIPIIKKESIVSLFEKGIRQDGRKLTDYRPLSITLDYAKKADGSALVKLGTTMVLAGTKLEIDKPYEDTPNQGNLIVNVELLPLAYETFEPGPPDENAIELARVVDRSLRDSKALDLTKLVIEPGKSVWTVWLDVYVLDYGGNVLDACTLASVAALYNTKVYKVEQISVNKNEVVGKLPLNYPVVTISVAKVDKYLVVDPDLDEESIMDAKISFSYTPDLKIVGIQKSGKGSMSLQDIDQAENTARSTAVKLLEELKKHLGI 2c38 X 3.1 BS01 AMP X 3 T88 R99 A134 D135 A136 R139 E179 T81 R92 A127 D128 A129 R132 E172 3.1.13.- 0000175,0000177,0000178,0003723,0004527,0005515,0005737,0006401,0016075,0016896 Q9UXC2 16285928 404 ERPKLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKEMHPRHLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVELFPRTAIDVFTEILQADAGSRLVSLMAASLALADAGIPMRDLIAGVAVGKADGVIILDLNETEDMWGEADMPIAMMPSLNQVTLFQLNGSMTPDEFRQAFDLAVKGINIIYNLEREALKSKYVEFKEEGV 2c5s A 2.5 BS01 AMP A 1 L183 L184 S185 S190 H208 F209 M268 G287 L178 L179 S180 S185 H203 F204 M263 G282 2.8.1.4 0000049,0002937,0003723,0004810,0005524,0005737,0005829,0009228,0009229,0016740,0016783,0034227,0052837,0140741 Q81KU0 16343540 1392 YEYILVRYGEMGKNRSKFVSTLKDNVKFKLKKFPNIKIDATHDRMYIQLNGEDHEAVSERLKDVFGIHKFNLAMKVPSELEDIKKGALAAFLQVKGDVKTFKITVHRSYKHFPMRTMELLPEIGGHILENTEDITVDVHNPDVNVRVEIRSGYSYIMCDERMGAGGLPVGVGGKVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHSPPFTSERAKQKVIDLAQELTKYCKRVTLHLVPFTEVQKTINKEIPSSYSMTVMRRMMMRITERIAEERNALAITTGESLGQVASQTLDSMHTINEVTNYPVIRPLITMDKLEIIKIAEEIGTYDISIRPYKPKREKANRFEAKYDFTPLIDEAVANKETMVLQTVE 2cfm A 1.8 BS01 AMP A 1 L226 A227 E247 K249 Y250 R254 R269 E299 F339 M401 K403 K420 L226 A227 E247 K249 Y250 R254 R269 E299 F339 M401 K403 K420 6.5.1.1 0003677,0003909,0003910,0005524,0006260,0006266,0006273,0006281,0006310,0016874,0046872,0051301,0071897 P56709 16820169 1563 MRYLELAQLYQKLEKTTMKLIKTRLVADFLKKVPDDHLEFIPYLILGEVFPEWDERELGVGEKLLIKAVAMATGIDAKEIEESVKDTGDLGESIALAVKKKKQKSFFSQPLTIKRVYQTLVKVAETTGEGSQDKKVKYLADLFMDAEPLEAKYLARTILGTMRTGVAEGLLRDAIAMAFHVKVELVERAYMLTSDFGYVAKIAKLEGNEGLAKVQVQLGKPIKPMLAQQAASIRDALLEMGGEAEFEIKYDGARVQVHKDGSKIIVYSRRLENVTRAIPEIVEALKEAIIPEKAIVEGELVAIGENGRPLPFQYVLRRFRRKHNIEEMMEKIPLELNLFDVLYVDGQSLIDTKFIDRRRTLEEIIKQNEKIKVAENLITKKVEEAEAFYKRALEMGHEGLMAKRLDAVYEPGNRGKKWLKIKPTMENLDLVIIGAEWGEGRRAHLFGSFILGAYDPETGEFLEVGKVGSGFTDDDLVEFTKMLKPLIIKEEGKRVWLQPKVVIEVTYQEIQKSPKYRSGFALRFPRFVALRDDKGPEDADTIERIAQLYELQEKMKGKVES 2cnq A 1.0 BS04 AMP A 1 E62 K66 V77 I79 I85 L107 L108 E61 K65 V76 I78 I84 L106 L107 6.3.2.6 0004639,0005515,0005524,0005634,0005737,0006164,0006189,0016874 P27616 1310 SITKTELDGILPLVARGKVRDIYEVDAGTLLFVATDRISAYDVIMENSIPEKGILLTKLSEFWFKFLSNDVRNHLVDIAPGKTIFDYLPAKLSEPKYKTQLEDRSLLVHKHKLIPLEVIVRGYITGSAWKEYVKTGTVHGLKQPQGLKESQEFPEPIFTPSTKAEHDENISPAQAAELVGEDLSRRVAELAVKLYSKCKDYAKEKGIIIADTKFEFGIDEKTNEIILVDEVLTPDSSRFWNGASYKVGESQDSYDKQFLRDWLTANKLNGVNGVKMPQDIVDRTRAKYIEAYETLTGSKWS 2d1q A 2.3 BS01 AMP A 1 S200 S201 H247 G318 A319 P320 G341 Y342 G343 L344 T345 D424 K531 S193 S194 H236 G307 A308 P309 G330 Y331 G332 L333 T334 D413 K520 S200 R220 H247 T345 E346 K445 Q450 K531 S193 R209 H236 T334 E335 K434 Q439 K520 1.13.12.7 0001676,0004467,0004497,0005524,0005777,0008218,0046872,0046949,0047077 P13129 16541080 1001 ENIVVGPKPFYPIEEGSAGTQLRKYMERYAKLGAIAFTNAVTGVDYSYAEYLEKSCCLGKALQNYGLVVDGRIALCSENCEEFFIPVIAGLFIGVGVAPTNEIYTLRELVHSLGISKPTIVFSSKKGLDKVITVQKTVTTIKTIVILDSKVDYRGYQCLDTFIKRNTPPGFQASSFKTVEVDRKEQVALIMNSSLPKGVQLTHENIVTRFSHARDPIYGNQVSPGTAVLTVVPFHHGFGMFTTLGYLICGFRVVMLTKFDEETFLKTLQDYKCTSVILVPTLFAILNKSELLNKYDLSNLVEIASGGAPLSKEVGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKPGASGKVVPLFKAKVIDLDTKKSLGPNRRGEVCVKGPMLMKGYVNNPEATKELIDEEGWLHTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPSIFDAGVAGVPDPVAGELPGAVVVLESGKNMTEKEVMDYVASQVSNAKRLRGGVRFVDEVPKGLTGKIDGRAIREILK 2d1r A 1.6 BS01 AMP A 1 S200 S201 H247 G318 A319 P320 G341 Y342 G343 L344 T345 D424 K531 S194 S195 H241 G312 A313 P314 G335 Y336 G337 L338 T339 D418 K525 S200 R220 H247 T345 E346 K445 Q450 K531 S194 R214 H241 T339 E340 K439 Q444 K525 1.13.12.7 0001676,0004467,0004497,0005524,0005777,0008218,0046872,0046949,0047077 P13129 16541080 1001 DENIVVGPKPFYPIEEGSAGTQLRKYMERYAKLGAIAFTNAVTGVDYSYAEYLEKSCCLGKALQNYGLVVDGRIALCSENCEEFFIPVIAGLFIGVGVAPTNEIYTLRELVHSLGISKPTIVFSSKKGLDKVITVQKTVTTIKTIVILDSKVDYRGYQCLDTFIKRNTPPGFQASSFKTVEVDRKEQVALIMNSSGSTGLPKGVQLTHENIVTRFSHARDPIYGNQVSPGTAVLTVVPFHHGFGMFTTLGYLICGFRVVMLTKFDEETFLKTLQDYKCTSVILVPTLFAILNKSELLNKYDLSNLVEIASGGAPLSKEVGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKPGASGKVVPLFKAKVIDLDTKKSLGPNRRGEVCVKGPMLMKGYVNNPEATKELIDEEGWLHTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPSIFDAGVAGVPDPVAGELPGAVVVLESGKNMTEKEVMDYVASQVSNAKRLRGGVRFVDEVPKGLTGKIDGRAIREILKKPV 2dcl A 2.28 BS01 AMP A 1 A41 G42 A43 T44 V77 A40 G41 A42 T43 V62 ? O59172 901 VEVEHWNTLRLRIYIGENDKWEGRPLYKVIVEKLREMGIAGATVYRGIYGFGTDLPIIVEVVDRGHNIEKVVNVIKPMIKDGMITVEPTIVLWVGTQEE 2dcl A 2.28 BS02 AMP B 1 G51 F52 G53 M98 G50 F51 G52 M83 ? O59172 902 VEVEHWNTLRLRIYIGENDKWEGRPLYKVIVEKLREMGIAGATVYRGIYGFGTDLPIIVEVVDRGHNIEKVVNVIKPMIKDGMITVEPTIVLWVGTQEE 2dcl B 2.28 BS01 AMP B 1 A43 T44 E75 V76 V77 A42 T43 E63 V64 V65 ? O59172 902 VEVEHWNTLRLRIYIGENDKWEGRPLYKVIVEKLREMGIAGATVYRGIYGFGKKSTDLPIIVEVVDRGHNIEKVVNVIKPMIKDGMITVEPTIVLWVG 2dcl B 2.28 BS02 AMP B 2 Y15 G51 F52 P71 D96 G97 M98 Y14 G50 F51 P59 D84 G85 M86 ? O59172 903 VEVEHWNTLRLRIYIGENDKWEGRPLYKVIVEKLREMGIAGATVYRGIYGFGKKSTDLPIIVEVVDRGHNIEKVVNVIKPMIKDGMITVEPTIVLWVG 2dcl C 2.28 BS01 AMP A 1 F52 G53 R65 P71 D96 M98 F51 G52 R55 P61 D86 M88 ? O59172 901 VEVEHWNTLRLRIYIGENDKWEGRPLYKVIVEKLREMGIAGATVYRGIYGFGKIRLSTDLPIIVEVVDRGHNIEKVVNVIKPMIKDGMITVEPTIVL 2dcl C 2.28 BS02 AMP B 2 G42 A43 T44 V77 G41 A42 T43 V67 ? O59172 903 VEVEHWNTLRLRIYIGENDKWEGRPLYKVIVEKLREMGIAGATVYRGIYGFGKIRLSTDLPIIVEVVDRGHNIEKVVNVIKPMIKDGMITVEPTIVL 2deu A 3.4 BS03 AMP C 1 G11 M12 S13 S18 F36 M37 T126 G127 H128 G7 M8 S9 S14 F32 M33 T122 G123 H124 2.8.1.13 0000049,0002143,0005524,0005737,0005829,0006400,0008033,0016740,0016783,0103016,1990228 P25745 16871210 134 AKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQPGKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILVVAQGHEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFDEPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV 2deu B 3.4 BS03 AMP D 1 G11 M12 S13 S18 F36 M37 T126 G127 H128 G7 M8 S9 S14 F32 M33 T122 G123 H124 2.8.1.13 0000049,0002143,0005524,0005737,0005829,0006400,0008033,0016740,0016783,0103016,1990228 P25745 16871210 134 AKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQPGKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILVVAQGHEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFDEPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV 2dsd A 2.6 BS03 AMP A 1 W28 A96 G97 E112 E116 E166 W15 A83 G84 E99 E103 E153 2.7.7.96,3.6.1.13,3.6.1.58 0000287,0003723,0005515,0005634,0005829,0006139,0006338,0006753,0009117,0009191,0016462,0016740,0016779,0016787,0017110,0019144,0019303,0019693,0030515,0042802,0042803,0044715,0044716,0046872,0047631,0055086,0070062,0140933,1990966 Q9UKK9 17052728 401 KQYIISEELISEGKWVKLEKTTYMDPTGKTRTWESVKRTTRKEQTADGVAVIPVLQRTLHYECIVLVKQFRPPMGGYCIEFPAGLIDDGETPEAAALRELEEETGYKGDIAECSPAVCMDPGLSNCTIHIVTVTINGDDAENARPKPKPGDGEFVEVISLPKNDLLQRLDALVAEEHLTVDARVYSYALALKHAN 2dsd A 2.6 BS04 AMP B 1 W46 E47 W33 E34 2.7.7.96,3.6.1.13,3.6.1.58 0000287,0003723,0005515,0005634,0005829,0006139,0006338,0006753,0009117,0009191,0016462,0016740,0016779,0016787,0017110,0019144,0019303,0019693,0030515,0042802,0042803,0044715,0044716,0046872,0047631,0055086,0070062,0140933,1990966 Q9UKK9 17052728 402 KQYIISEELISEGKWVKLEKTTYMDPTGKTRTWESVKRTTRKEQTADGVAVIPVLQRTLHYECIVLVKQFRPPMGGYCIEFPAGLIDDGETPEAAALRELEEETGYKGDIAECSPAVCMDPGLSNCTIHIVTVTINGDDAENARPKPKPGDGEFVEVISLPKNDLLQRLDALVAEEHLTVDARVYSYALALKHAN 2dsd B 2.6 BS01 AMP A 1 W46 E47 W33 E34 2.7.7.96,3.6.1.13,3.6.1.58 0000287,0003723,0005515,0005634,0005829,0006139,0006338,0006753,0009117,0009191,0016462,0016740,0016779,0016787,0017110,0019144,0019303,0019693,0030515,0042802,0042803,0044715,0044716,0046872,0047631,0055086,0070062,0140933,1990966 Q9UKK9 17052728 401 KQYIISEELISEGKWVKLEKTTYMDPTGKTRTWESVKRTTRKEQTADGVAVIPVLQRTLHYECIVLVKQFRPPMGGYCIEFPAGLIDDGETPEAAALRELEEETGYKGDIAECSPAVCMDPGLSNCTIHIVTVTINGDDAENARPKPKPGDGEFVEVISLPKNDLLQRLDALVAEEHLTVDARVYSYALALKHAN 2dsd B 2.6 BS04 AMP B 1 A96 G97 E112 A83 G84 E99 2.7.7.96,3.6.1.13,3.6.1.58 0000287,0003723,0005515,0005634,0005829,0006139,0006338,0006753,0009117,0009191,0016462,0016740,0016779,0016787,0017110,0019144,0019303,0019693,0030515,0042802,0042803,0044715,0044716,0046872,0047631,0055086,0070062,0140933,1990966 Q9UKK9 17052728 402 KQYIISEELISEGKWVKLEKTTYMDPTGKTRTWESVKRTTRKEQTADGVAVIPVLQRTLHYECIVLVKQFRPPMGGYCIEFPAGLIDDGETPEAAALRELEEETGYKGDIAECSPAVCMDPGLSNCTIHIVTVTINGDDAENARPKPKPGDGEFVEVISLPKNDLLQRLDALVAEEHLTVDARVYSYALALKHAN 2eck A 2.8 BS01 AMP A 1 T31 L35 R36 K57 L58 V59 R88 Q92 R156 T31 L35 R36 K57 L58 V59 R88 Q92 R156 K13 R88 R123 R156 R167 K13 R88 R123 R156 R167 2.7.4.3 0000287,0004017,0004550,0005515,0005524,0005737,0005829,0006139,0006172,0009123,0009132,0009165,0015951,0016208,0016301,0016310,0016776,0019205,0044209,0046940,0050145 P69441 16302237 215 MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG 2eck B 2.8 BS01 AMP B 1 T31 L35 R36 M53 K57 V59 R88 Q92 R156 T31 L35 R36 M53 K57 V59 R88 Q92 R156 K13 R88 R123 R156 R167 K13 R88 R123 R156 R167 2.7.4.3 0000287,0004017,0004550,0005515,0005524,0005737,0005829,0006139,0006172,0009123,0009132,0009165,0015951,0016208,0016301,0016310,0016776,0019205,0044209,0046940,0050145 P69441 16302237 215 MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG 2eqa A 1.8 BS01 AMP A 1 R59 N63 P64 T118 A120 P143 S144 R58 N62 P63 T117 A119 P142 S143 2.7.7.87 0000049,0003725,0005524,0005737,0006450,0008033,0016779,0061710 Q970S6 18004774 1379 TQIIKIDPLNPEIDKIKIAADVIRNGGTVAFPTETVYGLGANAFDGNACLKIFQAKNRPVDNPLIVHIADFNQLFEVAKDIPDKVLEIAQIVWPGPLTFVLKKTERVPKEVTAGLDTVAVRMPAHPIALQLIRESGVPIAAPSANLATRPSPTKAEDVIVDLNGRVDVIIDGGHTFFGVESTIINVTVEPVLLRPGPFTIEELKKLFGEIVIYKHYAPNTRLLLVENRNIFKDVVSLLSKKYKVALLIPKELSKEFEGLQQIILGSDENLYEVARNLFDSFRELDKLNVDLGIMIGFPERGIGFAIMNRARKASGFSIIKAISDVYKYVN 2f17 A 2.5 BS03 AMP A 1 N25 Q26 A45 D46 S74 D100 F101 G127 G129 G130 R131 Q134 N37 Q38 A57 D58 S86 D112 F113 G139 G141 G142 R143 Q146 2.7.6.2 0004788,0005524,0005829,0006772,0009229,0010510,0016301,0016310,0030975,0042723,0042802,0141200 Q9R0M5 16365036 301 HHSSGLVPRGSHMEHAFTPLEPLLPTGNLKYCLVVLNQPLDARFRHLWKKALLRACADGGANHLYDLTEGERESFLPEFVSGDFDSIRPEVKEYYTKKGCDLISTPDQDHTDFTKCLQVLQRKIEEKELQVDVIVTLGGLGGRFDQIMASVNTLFQATHITPVPIIIIQKDSLIYLLQPGKHRLHVDTGMEGSWCGLIPVGQPCNQVTTTGLKWNLTNDVLGFGTLVSTSNTYDGSGLVTVETDHPLLWTMAIKS 2f3d A 1.83 BS05 AMP A 1 V17 E20 G21 G26 T27 G28 E29 M30 K112 Y113 R140 M177 V8 E11 G12 G17 T18 G19 E20 M21 K103 Y104 R131 M168 D68 D74 E97 E98 D118 L120 D121 E280 D59 D65 E88 E89 D109 L111 D112 E271 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 23844654 435 DVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK 2fjb A 1.7 BS02 AMP A 1 Q145 R265 G274 L278 Q144 R264 G273 L277 1.8.99.2 0000104,0000166,0005886,0009055,0009061,0016491,0050660 O28603 16503650 1302 VYYPKKYELYKADEVPTEVVETDILIIGGGFSGCGAAYEAAYWAKLGGLKVTLVEKAAVERSGAVAQGLSAINTYIDLTGRSERQNTLEDYVRYVTLDMMGLAREDLVADYARHVDGTVHLFEKWGLPIWKTPDGKYVREGQWQIMIHGESYKPIIAEAAKMAVGEENIYERVFIFELLKDKNDPNAVAGAVGFSVREPKFYVFKAKAVILATGGATLLFRPRSTGEAAGRTWYAIFDTGSGYYMGLKAGAMLTQFEHRFIPFRFKDGYGPVGAWFLFFKCKAKNAYGEEYIKTRAAELEKYKPYGAAQPIPTPLRNHQVMLEIMDGNQPIYMHTEEALAELAGGDKKKLKHIYEEAFEDFLDMTVSQALLWACQNIDPQEQPSEAAPAEPYIMGSHSGEAGFWVCGPEDLMPEEYAKLFPLKYNRMTTVKGLFAIGDCAGANPHKFSSGSFTEGRIAAKAAVRFILEQKPNPEIDDAVVEELKKKAYAPMERFMQYKDLSTADDVNPEYILPWQGLVRLQKIMDEYAAGIATIYKTNEKMLQRALELLAFLKEDLEKLAARDLHELMRAWELVHRVWTAEAHVRHMLFRKETRWPGYYYRTDYPELNDEEWKCFVCSKYDAEKDEWTFEKVPYVQVIEWSF 2fjb A 1.7 BS03 AMP A 2 F264 F277 Y292 I293 V321 F263 F276 Y291 I292 V320 1.8.99.2 0000104,0000166,0005886,0009055,0009061,0016491,0050660 O28603 16503650 1303 VYYPKKYELYKADEVPTEVVETDILIIGGGFSGCGAAYEAAYWAKLGGLKVTLVEKAAVERSGAVAQGLSAINTYIDLTGRSERQNTLEDYVRYVTLDMMGLAREDLVADYARHVDGTVHLFEKWGLPIWKTPDGKYVREGQWQIMIHGESYKPIIAEAAKMAVGEENIYERVFIFELLKDKNDPNAVAGAVGFSVREPKFYVFKAKAVILATGGATLLFRPRSTGEAAGRTWYAIFDTGSGYYMGLKAGAMLTQFEHRFIPFRFKDGYGPVGAWFLFFKCKAKNAYGEEYIKTRAAELEKYKPYGAAQPIPTPLRNHQVMLEIMDGNQPIYMHTEEALAELAGGDKKKLKHIYEEAFEDFLDMTVSQALLWACQNIDPQEQPSEAAPAEPYIMGSHSGEAGFWVCGPEDLMPEEYAKLFPLKYNRMTTVKGLFAIGDCAGANPHKFSSGSFTEGRIAAKAAVRFILEQKPNPEIDDAVVEELKKKAYAPMERFMQYKDLSTADDVNPEYILPWQGLVRLQKIMDEYAAGIATIYKTNEKMLQRALELLAFLKEDLEKLAARDLHELMRAWELVHRVWTAEAHVRHMLFRKETRWPGYYYRTDYPELNDEEWKCFVCSKYDAEKDEWTFEKVPYVQVIEWSF 2fjb C 1.7 BS02 AMP C 1 Q2145 R2265 G2274 L2278 P2311 R2317 H2398 F2448 Q144 R264 G273 L277 P310 R316 H397 F447 1.8.99.2 0000104,0000166,0005886,0009055,0009061,0016491,0050660 O28603 16503650 1301 VYYPKKYELYKADEVPTEVVETDILIIGGGFSGCGAAYEAAYWAKLGGLKVTLVEKAAVERSGAVAQGLSAINTYIDLTGRSERQNTLEDYVRYVTLDMMGLAREDLVADYARHVDGTVHLFEKWGLPIWKTPDGKYVREGQWQIMIHGESYKPIIAEAAKMAVGEENIYERVFIFELLKDKNDPNAVAGAVGFSVREPKFYVFKAKAVILATGGATLLFRPRSTGEAAGRTWYAIFDTGSGYYMGLKAGAMLTQFEHRFIPFRFKDGYGPVGAWFLFFKCKAKNAYGEEYIKTRAAELEKYKPYGAAQPIPTPLRNHQVMLEIMDGNQPIYMHTEEALAELAGGDKKKLKHIYEEAFEDFLDMTVSQALLWACQNIDPQEQPSEAAPAEPYIMGSHSGEAGFWVCGPEDLMPEEYAKLFPLKYNRMTTVKGLFAIGDCAGANPHKFSSGSFTEGRIAAKAAVRFILEQKPNPEIDDAVVEELKKKAYAPMERFMQYKDLSTADDVNPEYILPWQGLVRLQKIMDEYAAGIATIYKTNEKMLQRALELLAFLKEDLEKLAARDLHELMRAWELVHRVWTAEAHVRHMLFRKETRWPGYYYRTDYPELNDEEWKCFVCSKYDAEKDEWTFEKVPYVQVIEWSF 2g1u A 1.5 BS01 AMP A 1 G16 R17 D37 K38 D58 A59 T80 N81 G13 R14 D34 K35 D55 A56 T77 N78 0005886,0006813,0015079 301 KQKSKYIVIFGCGRLGSLIANLASSSGHSVVVVDKNEYAFHRLNSEFSGFTVVGDAAEFETLKECGMEKADMVFAFTNDDSTNFFISMNARYMFNVENVIARVYDPEKIKIFEENGIKTICPAVLMIEKVKEFIIGS 2gm3 A 2.461 BS01 AMP A 1 A11 V12 N13 S26 C27 V53 P112 V130 G131 R133 V146 S147 A7 V8 N9 S22 C23 V49 P98 V116 G117 R119 V124 S125 ? 0005829,0005886,0016208 Q8LGG8 25921306 176 PTKVMVAVNASTIKDYPNPSISCKRAFEWTLEKIVRSNTSDFKILLLHVQVSIYASPEDFRDMRQSNKAKGLHLLEFFVNKCHEIGVGCEAWIKTGDPKDVICQEVKRVRPDFLVVGSRGLGTVSAFCVKHAECPVMTIKRNADETPSDPADD 2gm3 B 2.461 BS01 AMP B 1 A11 V12 N13 S26 C27 V53 P112 I116 V130 G131 R133 V146 S147 A7 V8 N9 S22 C23 V49 P91 I95 V109 G110 R112 V117 S118 ? 0005829,0005886,0016208 Q8LGG8 25921306 176 PTKVMVAVNASTIKDYPNPSISCKRAFEWTLEKIVRSNTSDFKILLLHVQVSIYASPEDFRDMGLHLLEFFVNKCHEIGVGCEAWIKTGDPKDVICQEVKRVRPDFLVVGSRGLGTVSAFCVKHAECPVMTIKRNADETPSDPAD 2gm3 C 2.461 BS01 AMP C 1 A11 V12 N13 S26 C27 V53 G131 R133 V146 S147 A7 V8 N9 S22 C23 V49 G117 R119 V124 S125 ? 0005829,0005886,0016208 Q8LGG8 25921306 176 PTKVMVAVNASTIKDYPNPSISCKRAFEWTLEKIVRSNTSDFKILLLHVQVSIYASPEDFRDMRQSNKAKGLHLLEFFVNKCHEIGVGCEAWIKTGDPKDVICQEVKRVRPDFLVVGSRGLGTVSAFCVKHAECPVMTIKRNADETPSDPADD 2gm3 D 2.461 BS01 AMP D 1 A11 V12 N13 S26 C27 V53 I116 G131 S132 R133 V146 S147 A7 V8 N9 S22 C23 V49 I102 G117 S118 R119 V124 S125 ? 0005829,0005886,0016208 Q8LGG8 25921306 176 PTKVMVAVNASTIKDYPNPSISCKRAFEWTLEKIVRSNTSDFKILLLHVQVSIYASPEDFRDMRQSNKAKGLHLLEFFVNKCHEIGVGCEAWIKTGDPKDVICQEVKRVRPDFLVVGSRGLGTVSAFCVKHAECPVMTIKRNADETPSDPADD 2gm3 E 2.461 BS01 AMP E 1 A11 V12 N13 S26 C27 V53 G131 R133 V146 S147 A7 V8 N9 S22 C23 V49 G117 R119 V124 S125 ? 0005829,0005886,0016208 Q8LGG8 25921306 176 PTKVMVAVNASTIKDYPNPSISCKRAFEWTLEKIVRSNTSDFKILLLHVQVSIYASPEDFRDMRQSNKAKGLHLLEFFVNKCHEIGVGCEAWIKTGDPKDVICQEVKRVRPDFLVVGSRGLGTVSAFCVKHAECPVMTIKRNADETPSDPADD 2gm3 F 2.461 BS01 AMP F 1 A11 V12 N13 S26 C27 V53 P112 V130 G131 R133 V146 S147 A7 V8 N9 S22 C23 V49 P93 V111 G112 R114 V119 S120 ? 0005829,0005886,0016208 Q8LGG8 25921306 176 PTKVMVAVNASTIKDYPNPSISCKRAFEWTLEKIVRSNTSDFKILLLHVQVSIYASPEDFRDMRQGLHLLEFFVNKCHEIGVGCEAWIKTGDPKDVICQEVKRVRPDFLVVGSRGLGTVSAFCVKHAECPVMTIKRNADETPSDPADD 2gmk A 1.65 BS01 AMP A 1 K9 K31 K9 K31 3.1.27.- 0003676,0004519,0004540,0050830 Ki=590uM -logKd/Ki=3.23, Ki=590uM P22069 18001769 940 QDWLTFQKKHITNTRDVDCDNIMSTNLFHCKDKNTFIYSRPEPVKAICKGIIASKNVLTTSEFYLSDCNVTSRPCKYKLKKSTNKFCVNCANQAPVHFVGVGSC 2gmk A 1.65 BS02 AMP A 2 K9 H10 H97 F98 K9 H10 H97 F98 3.1.27.- 0003676,0004519,0004540,0050830 Ki=590uM -logKd/Ki=3.23, Ki=590uM P22069 18001769 941 QDWLTFQKKHITNTRDVDCDNIMSTNLFHCKDKNTFIYSRPEPVKAICKGIIASKNVLTTSEFYLSDCNVTSRPCKYKLKKSTNKFCVNCANQAPVHFVGVGSC 2gsu A 2.0 BS03 AMP A 1 T90 F91 L123 Y174 Y205 D210 E211 H363 T47 F48 L80 Y131 Y162 D167 E168 H320 Ki=268uM -logKd/Ki=3.59, Ki=260uM 16893180 1004 TPHALLLISIDGLRADMLDRGITPNLSHLAREGVRARWMAPSYPSLTFPNHYTLVTGLRPDHHGIVHNSMRDPTLGGFWLSKSEAVGDARWWGGEPVWVGVENTGQHAATWSWPGSEAAIKGVRPSQWRHYQKGVRLDTRVDAVRGWLATDGAQRNRLVTLYFEHVDEAGHDHGPESRQYADAVRAVDAAIGRLLAGMQRDGTRARTNIIVVSDHGMAEVAPGHAISVEDIAPPQIATAITDGQVIGFEPLPGQQAAAEASVLGAHDHYDCWRKAELPARWQYGSHPRIPSLVCQMHEGWDALFPDKLAKRAQRGTRGSHGYDPALPSMRAVFLAQGPDLAQGKTLPGFDNVDVYALMSRLLGIPAAPNDGNPATLLPALRM 2gsu B 2.0 BS03 AMP B 1 T90 F91 L123 S155 Y174 K176 Y205 D210 E211 H214 H363 T47 F48 L80 S112 Y131 K133 Y162 D167 E168 H171 H320 Ki=268uM 16893180 1005 TPHALLLISIDGLRADMLDRGITPNLSHLAREGVRARWMAPSYPSLTFPNHYTLVTGLRPDHHGIVHNSMRDPTLGGFWLSKSEAVGDARWWGGEPVWVGVENTGQHAATWSWPGSEAAIKGVRPSQWRHYQKGVRLDTRVDAVRGWLATDGAQRNRLVTLYFEHVDEAGHDHGPESRQYADAVRAVDAAIGRLLAGMQRDGTRARTNIIVVSDHGMAEVAPGHAISVEDIAPPQIATAITDGQVIGFEPLPGQQAAAEASVLGAHDHYDCWRKAELPARWQYGSHPRIPSLVCQMHEGWDALFPDKLAKRAQRGTRGSHGYDPALPSMRAVFLAQGPDLAQGKTLPGFDNVDVYALMSRLLGIPAAPNDGNPATLLPALRM 2gxq A 1.2 BS01 AMP A 1 F3 L21 Q28 T47 G48 G50 K51 T52 I206 F3 L21 Q28 T47 G48 G50 K51 T52 I206 ? 0003676,0003724,0005524 O07897 16890241 401 MEFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAERLAPSQERGRKPRALVLTPTRELALQVASELTAVAPHLKVVAVYGGTGYGKQKEALLRGADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQTLLFSATLPSWAKRLAERYMKNPVLINVI 2gxs A 1.66 BS03 AMP A 1 F3 L21 Q28 T47 G48 G50 K51 T52 F3 L21 Q28 T47 G48 G50 K51 T52 ? 0003676,0003724,0005524 O07897 16890241 501 MEFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAERLAPSQERGRKPRALVLTPTRELALQVASELTAVAPHLKVVAVYGGTGYGKQKEALLRGADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQTLLFSATLPSWAKRLAERYMKNPVLINVI 2gxs B 1.66 BS03 AMP B 1 F3 L21 T23 T25 Q28 G48 G50 K51 T52 F3 L21 T23 T25 Q28 G48 G50 K51 T52 ? 0003676,0003724,0005524 O07897 16890241 502 MEFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAERLAPSQERGRKPRALVLTPTRELALQVASELTAVAPHLKVVAVYGGTGYGKQKEALLRGADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQTLLFSATLPSWAKRLAERYMKNPVLINVIK 2hbl A 2.3 BS03 AMP A 1 D238 E240 H241 W299 Q345 D112 E114 H115 W173 Q219 D238 E240 D296 A361 D365 D112 E114 D170 A235 D239 3.1.13.- 0000166,0000175,0000467,0003676,0006139,0008408,0044237 Q12149 16882719 2001 GMVEKPQLKFKSPIDNSESHPFIPLLKEKPNALKPLSESLRLVDDDENNPSHYPHPYEYEIDHQEYSPEILQIREEIPSKSWDDSVPIWVDTSTELESMLEDLKNTKEIAVDLEHHDYRSYYGIVCLMQISTRERDYLVDTLKLRENLHILNEVFTNPSIVKVFHGAFMDIIWLQRDLGLYVVGLFDTYHASKAIGLPRHSLAYLLENFANFKTSKKYQLADWRIRPLSKPMTAAARADTHFLLNIYDQLRNKLIESNKLAGVLYESRNVAKRRFEYSKYRPLTPSSEVYSPIEKESPWKILMYQYNIPPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTEHVRQNAKLLANLIRDALRNIKNTN 2hcr A 2.2 BS01 AMP A 1 R96 Q97 K99 H130 R94 Q95 K97 H128 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006144,0006164,0006221,0006796,0007399,0009156,0009165,0016301,0016310,0034418,0042802,0042803,0044249,0046101,0046872,0090407 P60891 16939420 3001 NIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLF 2hcr B 2.2 BS01 AMP B 1 R96 Q97 D101 H130 R94 Q95 D99 H128 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006144,0006164,0006221,0006796,0007399,0009156,0009165,0016301,0016310,0034418,0042802,0042803,0044249,0046101,0046872,0090407 P60891 16939420 3002 NIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKEDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVP 2hvs A 2.5 BS03 AMP E 1 Y5 K35 I36 N40 E99 F119 V207 K225 K227 Y6 K36 I37 N41 E100 F120 V208 K226 K228 6.5.1.3 0003972,0005524,0016874,0042245,0046872 P32277 17018278 236 SMFKKYSSLENHYNSKFIEKLYSLGLTGGEWVAREKIHGTNFSLIIERDKVTCAKRTGPILPAEDFFGYEIILKNYADSIKAVQDIMETSAVVSYQVFGEFAGPGIQKNVDYGDKDFYVFDIIVTTESGDVTYVDDYMMESFCNTFKFKMAPLLGRGKFEELIKLPNDLDSVVQDYNFTVDHAGLVDANKCVWNAEAKGEVFTAEGYVLKPCYPSWLRNGNRVAIKCKNSKFELSEADNKLVGILACYVTLNRVNNVISKIGEIGPKDFGKVMGLTVQDILEETSREGITLTQADNPSLIKKELVKMVQDVLRPAWIEL 2hvs B 2.5 BS04 AMP H 1 K35 I36 N40 E99 F119 K225 K36 I37 N41 E100 F120 K226 6.5.1.3 0003972,0005524,0016874,0042245,0046872 P32277 17018278 236 SMFKKYSSLENHYNSKFIEKLYSLGLTGGEWVAREKIHGTNFSLIIERDKVTCAKRTGPILPAEDFFGYEIILKNYADSIKAVQDIMETSAVVSYQVFGEFAGPGIQKNVDYGDKDFYVFDIIVTTESGDVTYVDDYMMESFCNTFKFKMAPLLGRGKFEELIKLPNDLDSVVQDYNFTVDHAGLVDANKCVWNAEAKGEVFTAEGYVLKPCYPSWLRNGNRVAIKCKNSKLSEADNKLVGILACYVTLNRVNNVISKIGEIGPKDFGKVMGLTVQDILEETSREGITLTQADNPSLIKKELVKMVQDVLRPAWIELVS 2i4i A 2.2 BS01 AMP A 1 Y200 T204 Q207 T226 G227 G229 K230 T231 Y34 T38 Q41 T60 G61 G63 K64 T65 3.6.4.13 0003676,0003724,0005524 O00571 17631897 600 MVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHY 2ivt A 2.6 BS01 AMP A 1 G733 V738 A756 K758 A807 L881 D892 G31 V36 A54 K56 A105 L158 D169 D850 D874 A876 R878 N879 D892 D127 D151 A153 R155 N156 D169 2.7.10.1 0004672,0004713,0005524,0006468 P07949 16928683 3015 GPLSLSVDAFKIPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVRALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKR 2j91 A 1.8 BS01 AMP A 1 R20 Y21 R303 R16 Y17 R288 H86 T158 H159 K295 E302 H82 T154 H155 K280 E287 4.3.2.2 0001666,0003824,0004018,0005829,0006164,0006167,0006177,0006189,0007584,0009060,0009152,0009168,0014850,0016829,0032991,0042594,0042802,0044208,0044209,0070626,0097294 P30566 1000 GDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIREMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYES 2j91 A 1.8 BS02 AMP D 1 R85 H86 D87 Q241 S334 A335 R338 R81 H82 D83 Q237 S319 A320 R323 H86 T158 H159 K295 E302 H82 T154 H155 K280 E287 4.3.2.2 0001666,0003824,0004018,0005829,0006164,0006167,0006177,0006189,0007584,0009060,0009152,0009168,0014850,0016829,0032991,0042594,0042802,0044208,0044209,0070626,0097294 P30566 1000 GDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIREMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYES 2j91 B 1.8 BS01 AMP B 1 R20 Y21 M299 R303 R16 Y17 M284 R288 H86 T158 H159 K295 E302 H82 T152 H153 K280 E287 4.3.2.2 0001666,0003824,0004018,0005829,0006164,0006167,0006177,0006189,0007584,0009060,0009152,0009168,0014850,0016829,0032991,0042594,0042802,0044208,0044209,0070626,0097294 P30566 1000 GDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIREMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVKAE 2j91 B 1.8 BS02 AMP C 1 Q241 R329 S334 R338 Q235 R314 S319 R323 H86 T158 H159 K295 E302 H82 T152 H153 K280 E287 4.3.2.2 0001666,0003824,0004018,0005829,0006164,0006167,0006177,0006189,0007584,0009060,0009152,0009168,0014850,0016829,0032991,0042594,0042802,0044208,0044209,0070626,0097294 P30566 1000 GDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIREMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVKAE 2j91 C 1.8 BS01 AMP B 1 R85 H86 D87 Q241 S334 R338 R81 H82 D83 Q237 S318 R322 H86 T158 H159 K295 E302 H82 T154 H155 K279 E286 4.3.2.2 0001666,0003824,0004018,0005829,0006164,0006167,0006177,0006189,0007584,0009060,0009152,0009168,0014850,0016829,0032991,0042594,0042802,0044208,0044209,0070626,0097294 P30566 1000 GDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIREMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPY 2j91 C 1.8 BS02 AMP C 1 R20 Y21 M299 R16 Y17 M283 H86 T158 H159 K295 E302 H82 T154 H155 K279 E286 4.3.2.2 0001666,0003824,0004018,0005829,0006164,0006167,0006177,0006189,0007584,0009060,0009152,0009168,0014850,0016829,0032991,0042594,0042802,0044208,0044209,0070626,0097294 P30566 1000 GDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIREMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPY 2j91 D 1.8 BS01 AMP A 1 R85 H86 D87 Q241 L331 S334 R338 R78 H79 D80 Q234 L314 S317 R321 H86 T158 H159 K295 E302 H79 T151 H152 K278 E285 4.3.2.2 0001666,0003824,0004018,0005829,0006164,0006167,0006177,0006189,0007584,0009060,0009152,0009168,0014850,0016829,0032991,0042594,0042802,0044208,0044209,0070626,0097294 P30566 1000 GDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITIREMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYE 2j91 D 1.8 BS02 AMP D 1 R20 Y21 M299 R303 R16 Y17 M282 R286 H86 T158 H159 K295 E302 H79 T151 H152 K278 E285 4.3.2.2 0001666,0003824,0004018,0005829,0006164,0006167,0006177,0006189,0007584,0009060,0009152,0009168,0014850,0016829,0032991,0042594,0042802,0044208,0044209,0070626,0097294 P30566 1000 GDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITIREMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYE 2j9d E 2.1 BS01 AMP E 1 G27 T29 L63 V64 E114 G29 T31 L65 V66 E116 ? 0005515,0005524,0005737,0005829,0006808,0030234 Q60381 17203075 1115 GSMKKVEAIIRPEKLEIVKKALSDAGYVGMTVSEVKGRGVQGGIVERYRGREYIVDLIPKVKIELVVKEEDVDNVIDIICENARTGNPGDGKIFVIPVERVVRVRTKEEGKEALEE 2j9d F 2.1 BS01 AMP E 1 G35 V38 K58 G87 G89 K90 G37 V40 K58 G87 G89 K90 ? 0005515,0005524,0005737,0005829,0006808,0030234 Q60381 17203075 1115 GSMKKVEAIIRPEKLEIVKKALSDAGYVGMTVSEVKGRGVGIVERYRGREYIVDLIPKVKIELVVKEEDVDNVIDIICENARTGNPGDGKIFVIPVERVVRVRTKEEGKEALL 2jb7 A 1.65 BS01 AMP A 1 N20 W95 A117 Y165 N16 W91 A113 Y161 ? 0000166 Q8ZVF7 1168 SIKFELIDVPIPQGTNVIIGQAHFIKTVEDLYEALVTSVPGVKFGIAFCEASGKRLVRHEANDEELRNLAIDLCKKIAAGHVFVIYIRNAWPINVLNAIKNVPEVVRIFAATANPLKVIVAEVEPERRGVVGVVDGHSPLGVETEKDREERKKFLREVVKYKL 2jb7 A 1.65 BS02 AMP B 1 F28 S56 F24 S52 ? 0000166 Q8ZVF7 1168 SIKFELIDVPIPQGTNVIIGQAHFIKTVEDLYEALVTSVPGVKFGIAFCEASGKRLVRHEANDEELRNLAIDLCKKIAAGHVFVIYIRNAWPINVLNAIKNVPEVVRIFAATANPLKVIVAEVEPERRGVVGVVDGHSPLGVETEKDREERKKFLREVVKYKL 2jb7 B 1.65 BS01 AMP B 1 N20 W95 A117 Y165 N16 W91 A113 Y161 ? 0000166 Q8ZVF7 1168 SIKFELIDVPIPQGTNVIIGQAHFIKTVEDLYEALVTSVPGVKFGIAFCEASGKRLVRHEANDEELRNLAIDLCKKIAAGHVFVIYIRNAWPINVLNAIKNVPEVVRIFAATANPLKVIVAEVEPERRGVVGVVDGHSPLGVETEKDREERKKFLREVVKYKL 2jb7 B 1.65 BS02 AMP C 1 F28 S56 F24 S52 ? 0000166 Q8ZVF7 1168 SIKFELIDVPIPQGTNVIIGQAHFIKTVEDLYEALVTSVPGVKFGIAFCEASGKRLVRHEANDEELRNLAIDLCKKIAAGHVFVIYIRNAWPINVLNAIKNVPEVVRIFAATANPLKVIVAEVEPERRGVVGVVDGHSPLGVETEKDREERKKFLREVVKYKL 2jb7 C 1.65 BS01 AMP A 1 H27 F28 S56 H22 F23 S51 ? 0000166 Q8ZVF7 1168 IKFELIDVPIPQGTNVIIGQAHFIKTVEDLYEALVTSVPGVKFGIAFCEASGKRLVRHEANDEELRNLAIDLCKKIAAGHVFVIYIRNAWPINVLNAIKNVPEVVRIFAATANPLKVIVAEVEPERRGVVGVVDGHSPLGVETEKDREERKKFLREVVKYKL 2jb7 C 1.65 BS02 AMP C 1 N20 W95 A117 Y165 N15 W90 A112 Y160 ? 0000166 Q8ZVF7 1168 IKFELIDVPIPQGTNVIIGQAHFIKTVEDLYEALVTSVPGVKFGIAFCEASGKRLVRHEANDEELRNLAIDLCKKIAAGHVFVIYIRNAWPINVLNAIKNVPEVVRIFAATANPLKVIVAEVEPERRGVVGVVDGHSPLGVETEKDREERKKFLREVVKYKL 2jgd A 2.6 BS01 AMP A 1 S302 H313 R337 M526 W533 T673 R710 M711 S207 H218 R242 M405 W412 T552 R589 M590 1.2.4.2 0000166,0000287,0004591,0005515,0005737,0005829,0006099,0016491,0016624,0030976,0042802,0045252 P0AFG3 17367808 1934 DTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQDDLDPSFHDLTEDFQETFNVGSFAETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRWIQQRIESRATFNSEEKKRFLSELTAAEGLERYLGAKFPGRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGHMSVHQKQQQDLVNDALNVE 2jgd B 2.6 BS01 AMP B 1 S302 H313 R337 W533 T673 R710 M711 S208 H219 R243 W409 T547 R584 M585 1.2.4.2 0000166,0000287,0004591,0005515,0005737,0005829,0006099,0016491,0016624,0030976,0042802,0045252 P0AFG3 17367808 1934 TNVKQVKVLQLINAYRFRGHQHANLDPLGLWKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLGAKFPRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYADRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGYMSVHQKQQQDLVNDALNVE 2nsy A 2.0 BS02 AMP A 1 G44 I45 S46 S51 R78 L79 Q84 R139 T157 D173 T208 A209 G44 I45 S46 S51 R78 L79 Q84 R139 T157 D173 T208 A209 D50 E162 D50 E162 6.3.1.5 0003952,0004359,0005524,0005737,0008795,0009435,0016874,0030435,0046872 P08164 9753692 300 SMQEKIMRELHVKPSIDPKQEIEDRVNFLKQYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVESIREEGGDAQFIAVRLPHGTQQDEDDAQLALKFIKPDKSWKFDIKSTVSAFSDQYQQETGDQLTDFNKGNVKARTRMIAQYAIGGQEGLLVLGTDHAAEAVTGFFTKYGDGGADLLPLTGLTKRQGRTLLKELGAPERLYLKEPTADLLDEKPQQSDETELGISYDEIDDYLEGKEVSAKVSEALEKRYSMTEHKRQVPASMFDDWWK 2nsy B 2.0 BS03 AMP B 1 G44 I45 S46 S51 L79 Q84 R139 T157 E162 D173 T208 A209 G44 I45 S46 S51 L79 Q84 R139 T157 E162 D173 T208 A209 D50 E162 D50 E162 6.3.1.5 0003952,0004359,0005524,0005737,0008795,0009435,0016874,0030435,0046872 P08164 9753692 302 SMQEKIMRELHVKPSIDPKQEIEDRVNFLKQYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVESIREEGGDAQFIAVRLPHGTQQDEDDAQLALKFIKPDKSWKFDIKSTVSAFSDQYQQETGDQLTDFNKGNVKARTRMIAQYAIGGQEGLLVLGTDHAAEAVTGFFTKYGDGGADLLPLTGLTKRQGRTLLKELGAPERLYLKEPTADLLDEKPQQSDETELGISYDEIDDYLEGKEVSAKVSEALEKRYSMTEHKRQVPASMFDDWWK 2oox E 2.6 BS01 AMP E 1 R141 T191 L195 A196 I216 S217 I303 S305 D308 R140 T190 L194 A195 I215 S216 I302 S304 D307 ? 0005515,0005524,0005634,0005737,0005829,0006357,0007165,0010514,0016208,0019887,0019901,0030295,0031588,0043531 Q10343 17289942 401 MDVQETQKGALKEIQAFIRSRTSYDVLPTSFRLIVFDVTLFVKTSLSLLTLNNIVSAPLWDSEANKFAGLLTMADFVNVIKYYYQSSSFPEAIAEIDKFRLLGLREVERKIGAIPPETIYVHPMHSLMDACLAMSKSRARRIPLIDVDGETGSEMIVSVLTQYRILKFISMNCKETAMLRVPLNQMTIGTWSNLATASMETKVYDVIKMLAEKNISAVPIVNSEGTLLNVYESVDVMHLIQDGDYSNLDLSVGEALLKRPANFDGVHTCRATDRLDGIFDAIKHSRVHRLFVVDENLKLEGILSLADILNYIIYDKTTTPGVPEQTDNFESAV 2oox G 2.6 BS01 AMP G 1 R139 R141 T191 A196 I216 S217 I303 S305 D308 R138 R140 T190 A195 I215 S216 I302 S304 D307 ? 0005515,0005524,0005634,0005737,0005829,0006357,0007165,0010514,0016208,0019887,0019901,0030295,0031588,0043531 Q10343 17289942 401 MDVQETQKGALKEIQAFIRSRTSYDVLPTSFRLIVFDVTLFVKTSLSLLTLNNIVSAPLWDSEANKFAGLLTMADFVNVIKYYYQSSSFPEAIAEIDKFRLLGLREVERKIGAIPPETIYVHPMHSLMDACLAMSKSRARRIPLIDVDGETGSEMIVSVLTQYRILKFISMNCKETAMLRVPLNQMTIGTWSNLATASMETKVYDVIKMLAEKNISAVPIVNSEGTLLNVYESVDVMHLIQDGDYSNLDLSVGEALLKRPANFDGVHTCRATDRLDGIFDAIKHSRVHRLFVVDENLKLEGILSLADILNYIIYDKTTTPGVPE 2oun A 1.56 BS02 AMP A 1 H525 H563 D564 L635 D674 L675 I692 Q726 F729 H79 H117 D118 L189 D228 L229 I246 Q280 F283 3.1.4.17 0004114,0007165,0008081 Q9Y233 17389385 401 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 2owo A 2.3 BS04 AMP D 1 S81 L82 E113 K115 A120 E173 Y225 V288 K290 S81 L82 E113 K115 A120 E173 Y225 V288 K290 Y225 T427 Y225 T427 6.5.1.2 0003677,0003911,0005515,0005829,0006259,0006260,0006266,0006281,0006288,0016874,0046872,0070403 P15042 17466627 53 MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKNNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLAQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAP 2p2f A 2.58 BS02 AMP A 1 G387 E388 P389 T412 W413 W414 Q415 T416 D500 I512 R515 N521 R526 G382 E383 P384 T407 W408 W409 Q410 T411 D495 I507 R510 N516 R521 T264 T416 E417 N521 R526 K609 T259 T411 E412 N516 R521 K604 6.2.1.1 0003987,0005524,0005829,0006085,0006935,0016208,0016874,0016877,0019427,0046872 Q8ZKF6 17497934 999 KHAIPANIADRCLINPEQYETKYKQSINDPDTFWGEQGKILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDTSQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITADEGVRAGRSIPLKKNVDDALKNPNVTSVEHVIVLKRTGSDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGKEKCPVVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHAIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTSSTLADPGVVEKLLEEKQA 2p2f B 2.58 BS02 AMP B 1 G387 E388 P389 D411 T412 W413 W414 Q415 T416 D500 I512 R515 R526 G383 E384 P385 D407 T408 W409 W410 Q411 T412 D496 I508 R511 R522 T264 T416 E417 N521 R526 K609 T260 T412 E413 N517 R522 K605 6.2.1.1 0003987,0005524,0005829,0006085,0006935,0016208,0016874,0016877,0019427,0046872 Q8ZKF6 17497934 998 HKHAIPANIADRCLINPEQYETKYKQSINDPDTFWGEQGKILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDTSQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITADEGVRAGRSIPLKKNVDDALKNPNVTSVEHVIVLKRTGSDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGKEKCPVVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHAIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDDPGVVEKLLEEKQA 2ptq A 2.0 BS02 AMP A 1 N90 H91 Q247 R335 L337 S340 T341 R344 N90 H91 Q247 R335 L337 S340 T341 R344 H91 T170 N171 S296 K301 E308 H91 T170 N171 S296 K301 E308 4.3.2.2 0003824,0004018,0005515,0005829,0006164,0006188,0006189,0006974,0009152,0016829,0044208,0070626,0097216 P0AB89 17531264 2200 MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFAADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGLKDLAVQYRDIPLLSRTNGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAITMVDELKHHH 2ptq A 2.0 BS04 AMP B 1 R15 Y16 N309 R15 Y16 N309 H91 T170 N171 S296 K301 E308 H91 T170 N171 S296 K301 E308 4.3.2.2 0003824,0004018,0005515,0005829,0006164,0006188,0006189,0006974,0009152,0016829,0044208,0070626,0097216 P0AB89 17531264 2100 MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFAADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGLKDLAVQYRDIPLLSRTNGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAITMVDELKHHH 2ptq B 2.0 BS02 AMP A 1 R15 Y16 N309 R15 Y16 N309 H91 T170 N171 S296 K301 E308 H91 T170 N171 S296 K301 E308 4.3.2.2 0003824,0004018,0005515,0005829,0006164,0006188,0006189,0006974,0009152,0016829,0044208,0070626,0097216 P0AB89 17531264 2200 MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFAADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGLKDLAVQYRDIPLLSRTNGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAITMVDELKHH 2ptq B 2.0 BS04 AMP B 1 N90 H91 D92 Q247 R335 L337 S340 T341 R344 N90 H91 D92 Q247 R335 L337 S340 T341 R344 H91 T170 N171 S296 K301 E308 H91 T170 N171 S296 K301 E308 4.3.2.2 0003824,0004018,0005515,0005829,0006164,0006188,0006189,0006974,0009152,0016829,0044208,0070626,0097216 P0AB89 17531264 2100 MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFAADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGLKDLAVQYRDIPLLSRTNGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAITMVDELKHH 2pza A 2.4 BS02 AMP A 1 G45 I46 S47 S52 R79 L80 Q85 R140 T158 E163 D174 T209 A210 G45 I46 S47 S52 R79 L80 Q85 R140 T158 E163 D174 T209 A210 D51 E163 D51 E163 6.3.1.5 0003952,0004359,0005524,0005737,0008795,0009435,0016874,0046872 Q81RP3 17642516 4000 MTLQEQIMKALHVQPVIDPKAEIRKRVDFLKDYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVEEIRNEGGNATFIAVRLPYKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYENLLDESLTDFNKGNVKARIRMVTQYAIGGQKGLLVIGTDHAAEAVTGFFTKFGDGGADLLPLTGLTKRQGRALLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKTVPADVAEKIEKRYTVSEHKRQVPASMFDDWWKLAAALEH 2pza B 2.4 BS02 AMP B 1 G45 I46 S47 S52 L80 Q85 R140 T158 E163 D174 T209 A210 G45 I46 S47 S52 L80 Q85 R140 T158 E163 D174 T209 A210 D51 E163 D51 E163 6.3.1.5 0003952,0004359,0005524,0005737,0008795,0009435,0016874,0046872 Q81RP3 17642516 5000 MTLQEQIMKALHVQPVIDPKAEIRKRVDFLKDYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVEEIRNEGGNATFIAVRLPYKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYENLLDESLTDFNKGNVKARIRMVTQYAIGGQKGLLVIGTDHAAEAVTGFFTKFGDGGADLLPLTGLTKRQGRALLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKTVPADVAEKIEKRYTVSEHKRQVPASMFDDWWKLAAALEH 2q2t A 2.3 BS04 AMP A 1 T25 K27 I28 E67 F98 M164 K186 K188 T25 K27 I28 E67 F98 M164 K186 K188 ? 0000166,0003909,0003910,0005524,0006260,0006281,0006310,0016874 O41026 17618295 300 MAITKPLLAATLENIEDVQFPCLATPKIDGIRSVKQTQMLSRTFKPIRNSVMNRLLTELLPEGSDGEISIEGATFQDTTSAVMTGHKMYNAKFSYYWFDYVTDDPLKKYIDRVEDMKNYITVHPHILEHAQVKIIPLIPVEINNITELLQYERDVLSKGFEGVMIRKPDGKYKFGRSTLKEGILLKMKQFKDAEATIISMTALFKNTNTKTKDNFGYSKRSTHKSGKVEEDVMGSIEVDYDGVVFSIGTGFDADQRRDFWQNKESYIGKMVKFKYFEMGSKDCPRFPVFIGIR 2q4h A 1.834 BS03 AMP A 1 F65 A74 N94 L95 Y96 N173 G179 A180 S181 M182 H186 Q188 F33 A42 N62 L63 Y64 N133 G139 A140 S141 M142 H146 Q148 C63 C66 H133 N173 S181 H184 H186 Q188 C31 C34 H93 N133 S141 H144 H146 Q148 2.7.7.- 0005975,0006006,0006012,0008108,0008270,0016779,0017103,0043531,0046872,0047345,0080040 Q9FK51 17850744 601 SPELRKDPVTNRWVIFSPRPTDFKSKSPSSCPFCIGREQECAPELFRVPDHDPNWKLRVIENLYPALSRNLETQSRTIVGFGFHDVVIESPVHSIQLSDIDPVGIGDILIAYKKRINQIAQHDSINYIQVFKNQGASAGASMSHSHSQMMALPVVPPTVSSRLDGTKDYFEETGKCCLCEAKSKHFVIDESSHFVSVAPFAATYPFEIWIIPKDHSSHFHHLDDVKAVDLGGLLKLMLQKIAKQLNDPPYNYMIHTSPLKVTESQLPYTHWFLQIVPQLSGVGGFEIGTGCYINPVFPEDVAKVMREVSLT 2q4h B 1.834 BS03 AMP B 1 A74 N94 L95 Y96 A180 S181 M182 H186 Q188 A37 N57 L58 Y59 A135 S136 M137 H141 Q143 C63 C66 H133 N173 S181 H184 H186 Q188 C26 C29 H88 N128 S136 H139 H141 Q143 2.7.7.- 0005975,0006006,0006012,0008108,0008270,0016779,0017103,0043531,0046872,0047345,0080040 Q9FK51 17850744 602 QSPELRKDPVTNRWVIFSPTDFKSSCPFCIGREQECAPELFRVPDHDPNWKLRVIENLYPALSRNLETQSRTIVGFGFHDVVIESPVHSIQLSDIDPVGIGDILIAYKKRINQIAQHDSINYIQVFKNQGASAGASMSHSHSQMMALPVVPPTVSSRLDGTKDYFEETGKCCLCEAKSKHFVIDESSHFVSVAPFAATYPFEIWIIPKDHSSHFHHLDDVKAVDLGGLLKLMLQKIAKQLNDPPYNYMIHTSPLKVTESQLPYTHWFLQIVPQLSGVGGFEIGTGCYINPVFPEDVAKVMREVSL 2q8m A 2.05 BS05 AMP A 1 I8 Q12 F15 A18 T19 G20 E21 L22 K104 Y105 I8 Q12 F15 A18 T19 G20 E21 L22 K82 Y83 E89 E90 D110 L112 D113 E275 E67 E68 D88 L90 D91 E253 3.1.3.11 0000166,0000287,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030388,0032991,0042132,0042578,0042802,0046872 Ki=94uM -logKd/Ki=4.03, Ki=94uM P0A993 17567577 341 MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAGLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVKKYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA 2q8m B 2.05 BS04 AMP B 1 I8 Q12 F15 A18 T19 G20 E21 L22 K104 Y105 I8 Q12 F15 A18 T19 G20 E21 L22 K82 Y83 E89 E90 D110 L112 D113 E275 E67 E68 D88 L90 D91 E253 3.1.3.11 0000166,0000287,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030388,0032991,0042132,0042578,0042802,0046872 Ki=94uM P0A993 17567577 343 MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAGLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVKKYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA 2qga B 2.01 BS01 AMP B 1 H86 D87 Q245 R333 L335 S338 T339 R342 H86 D87 Q245 R326 L328 S331 T332 R335 H86 T167 H168 S294 K299 E306 H86 T167 H168 S287 K292 E299 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0046872,0070626 A5KBL5 908 EHLKNISPIDGRYKKACGELSAFFSEHALIKHRIIVEVRWLLFLNEEELFFEKVTDHSVEVLNQIATNITDSDIARVKAIEEETNHDVKAVEYFVKEKLKNSKREDLLKIKEYVHYLCTSEDINNVAYATCLKACLNDVVIPCLEKIMLKLKDLAVEYSHVPLLSRTHGQPASSTTFGKEMANFYARIHHHVGVIRRVKVCAKFNGAVGNFNAHKVASKDTDWVNTIGLFLKKHFNLTYSIYCTQIQDHDYICELCDGLARANGTLIDLCVDIWLYISNNLLKLKSSTMPHKVNPIDFENAEGNLHIANAFFKLFSSKLPTSRLQRDLSDSTVLRNIGSSLAYCLIAYKSVLKGLNKIDIDRRNLEEELNQNWSTLAEPIQIVMKRHNYVDAYEELKQFTRGKVIDQKIMQEFIKTKCAFLPQDVVDQLLELTPATYTGYADYLAKNVERLSGE 2qga C 2.01 BS01 AMP C 1 N85 H86 D87 Q245 R333 S338 T339 R342 N85 H86 D87 Q245 R328 S333 T334 R337 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0046872,0070626 A5KBL5 907 EHLKNISPIDGRYKKACGELSAFFSEHALIKHRIIVEVRWLLFLNEEELFFEKVTDHSVEVLNQIATNITDSDIARVKAIEEETNHDVKAVEYFVKEKLKNSKREDLLKIKEYVHYLCTSEDINNVAYATCLKACLNDVVIPCLEKIMLKLKDLAVEYSHVPLLSRTHGQPASSTTFGKEMANFYARIHHHVGVIRRVKVCAKFNGAVGNFNAHKVASKDTDWVNTIGLFLKKHFNLTYSIYCTQIQDHDYICELCDGLARANGTLIDLCVDIWLYISNNLLKLKVGSSTMPHKVNPIDFENAEGNLHIANAFFKLFSSKLPTSRLQRDLSDSTVLRNIGSSLAYCLIAYKSVLKGLNKIDIDRRNLEEELNQNWSTLAEPIQIVMKRHNYVDAYEELKQFTRGKVIDQKIMQEFIKTKCAFLPQDVVDQLLELTPATYTGYADYLAKNVERLSG 2qjt A 2.3 BS04 AMP A 1 Y190 F203 G235 F236 E250 D308 Y186 F199 G231 F232 E246 D304 2.7.7.1,3.6.1.- 0000166,0000309,0003824,0009058,0016779,0016787,0046872 Q5NHR1 18275811 601 MYDISVFIGRFQPFHKGHLHNIIIALQNSKKVIINIGSCFNTPNIKNPFSFEQRKQMIESDLQVAGIDLDTVVIEPLADYFYQEQKWQDELRKNVYKHAKNNNSIAIVGSSSYYIRSFPEWDYIGVDNYKNFNATEFRQKFYNGIISKQYMCSNDPKLGTYNFLTKFMDTQVYQDLVAENNYVIEYKRLWLKAPFKPNFVTVDALVIVNDHILMVQRKAHPGKDLWALPGGFLECDETIAQAIIRELFEETNINLTHEQLAIAKRCEKVFDYPDRSVRGRTISHVGLFVFDQWPSLPEINAADDAKDVKWISLGSNIKNICDRMLEDHYQIITILLEECG 2qjt B 2.3 BS03 AMP B 1 Y190 F203 G235 F236 E250 D308 Y190 F203 G235 F236 E250 D308 2.7.7.1,3.6.1.- 0000166,0000309,0003824,0009058,0016779,0016787,0046872 Q5NHR1 18275811 602 MYDISVFIGRFQPFHKGHLHNIIIALQNSKKVIINIGSCFNTPNIKNPFSFEQRKQMIESDLQVAGIDLDTVVIEPLADYFYQEQKWQDELRKNVYKHAKNNNSIAIVGHIKDSSSYYIRSFPEWDYIGVDNYKNFNATEFRQKFYNGIISKQYMCSNDPKLGTYNFLTKFMDTQVYQDLVAENNYVIEYKRLWLKAPFKPNFVTVDALVIVNDHILMVQRKAHPGKDLWALPGGFLECDETIAQAIIRELFEETNINLTHEQLAIAKRCEKVFDYPDRSVRGRTISHVGLFVFDQWPSLPEINAADDAKDVKWISLGSNIKNICDRMLEDHYQIITILLEECG 2qrc G 2.7 BS01 AMP G 1 R141 T191 L195 A196 I216 S217 I303 S305 D308 R141 T191 L195 A196 I216 S217 I303 S305 D308 ? 0005515,0005524,0005634,0005737,0005829,0006357,0007165,0010514,0016208,0019887,0019901,0030295,0031588,0043531 Q10343 17937917 1001 AMDVQETQKGALKEIQAFIRSRTSYDVLPTSFRLIVFDVTLFVKTSLSLLTLNNIVSAPLWDSEANKFAGLLTMADFVNVIKYYYQSSSFPEAIAEIDKFRLLGLREVERKIGAIPPETIYVHPMHSLMDACLAMSKSRARRIPLIDVDGETGSEMIVSVLTQYRILKFISMNCKETAMLRVPLNQMTIGTWSNLATASMETKVYDVIKMLAEKNISAVPIVNSEGTLLNVYESVDVMHLIQDGDYSNLDLSVGEALLKRPANFDGVHTCRATDRLDGIFDAIKHSRVHRLFVVDENLKLEGILSLADILNYIIYDKDNFESAV 2qrk A 1.75 BS01 AMP A 1 L202 G203 R204 C205 D227 I228 T231 I250 L200 G201 R202 C203 D225 I226 T229 I248 1.5.1.7 0003729,0004753,0004754,0005515,0005737,0005777,0006553,0009085,0016491,0016558,0019878 Ki=55uM -logKd/Ki=4.26, Ki=55uM P38998 17939687 500 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDRHCARV 2r7m A 2.3 BS01 AMP A 1 I154 K156 Y166 E199 Y201 V202 E230 F309 I154 K156 Y160 E193 Y195 V196 E224 F303 6.3.4.23 0000287,0005524,0006164,0006188,0006189,0016874,0016879,0046872 Q57600 18069798 400 MISKDEILEIFDKYNKDEITIATLGSHTSLHILKGAKLEGFSTVCITMKGRDVPYKRFKVADKFIYVDNFSDIKNEEIQEKLRELNSIVVPHGSFIAYCGLDNVENSFLVPMFGNRRILRWESERSLEGKLLREAGLRVPKKYESPEDIDGTVIVKFPGYFIASSTEEFYKKAEDLKKRGILTDEDIANAHIEEYVVGTNFCIHYFYSPLKDEVELLGMDKRYESNIDGLVRIPAKDQLEMNINPSYVITGNIPVVIRESLLPQVFEMGDKLVAKAKELVPPGMIGPFCLQSLCNENLELVVFEMSARVDGGTNSFMNGGPYSFLYNGEPLSMGQRIAREIKMALQLDMIDKIIS 2r7m A 2.3 BS02 AMP A 2 H27 S94 R228 I255 N258 G317 H27 S94 R222 I249 N252 G311 6.3.4.23 0000287,0005524,0006164,0006188,0006189,0016874,0016879,0046872 Q57600 18069798 401 MISKDEILEIFDKYNKDEITIATLGSHTSLHILKGAKLEGFSTVCITMKGRDVPYKRFKVADKFIYVDNFSDIKNEEIQEKLRELNSIVVPHGSFIAYCGLDNVENSFLVPMFGNRRILRWESERSLEGKLLREAGLRVPKKYESPEDIDGTVIVKFPGYFIASSTEEFYKKAEDLKKRGILTDEDIANAHIEEYVVGTNFCIHYFYSPLKDEVELLGMDKRYESNIDGLVRIPAKDQLEMNINPSYVITGNIPVVIRESLLPQVFEMGDKLVAKAKELVPPGMIGPFCLQSLCNENLELVVFEMSARVDGGTNSFMNGGPYSFLYNGEPLSMGQRIAREIKMALQLDMIDKIIS 2r84 A 1.9 BS01 AMP A 1 I130 K132 Y142 Q173 Y175 V176 Y227 F282 I130 K132 Y137 Q168 Y170 V171 Y222 F277 6.3.4.23 0000287,0005524,0006164,0006188,0006189,0016874,0016879,0046872 Q8U0R7 18069798 400 MKVRIATYASHSALQILKGAKDEGFETIAFGSSKVKPLYTKYFPVADYFIEEKYPEEELLNLNAVVVPTGSFVAHLGIELVENMKVPYFGNKRVLRWESDRNLERKWLKKAGIRVPEVYEDPDDIEKPVIVKPGKGYFLAKDPEDFWRKAEKFLGIKRKEDLKNIQIQEYVLGVPVYPHYFYSKVREELELMSIDRRYESNVDAIGRIPAKDQLEFDMDITYTVIGNIPIVLRESLLMDVIEAGERVVKAAEELMGGLWGPFCLEGVFTPDLEFVVFEISARIVAGTNIFVNGSPYTWLRYDRPVSTGRRIAMEIREAIENDMLEKVLT 2r84 B 1.9 BS01 AMP B 1 P116 I130 K132 Y142 E174 Y175 V176 F282 P116 I130 K132 Y134 E153 Y154 V155 F261 6.3.4.23 0000287,0005524,0006164,0006188,0006189,0016874,0016879,0046872 Q8U0R7 18069798 400 MKVRIATYASHSALQILKGAKDEGFETIAFGSSKVKPLYTKYFPVADYFIEEKYPEEELLNLNAVVVPTGSFVAHLGIELVENMKVPYFGNKRVLRWESDRNLERKWLKKAGIRVPEVYEDPDDIEKPVIVKGYFLAKDPEDFWRKAEIQIQEYVLGVPVYPHYFYSKVREELELMSIDRRYESNVDAIGRIPAKDQLEFDMDITYTVIGNIPIVLRESLLMDVIEAGERVVKAAEELMGGLWGPFCLEGVFTPDLEFVVFEISARIVAGTNIFVNGSPYTWLRYDRPVSTGRRIAMEIREAIENDMLEKVLT 2r85 A 1.7 BS01 AMP A 1 P116 I130 K132 Y142 Q173 Y175 V176 Y227 F282 P116 I130 K132 Y138 Q169 Y171 V172 Y223 F278 6.3.4.23 0000287,0005524,0006164,0006188,0006189,0016874,0016879,0046872 Q8U0R7 18069798 400 MKVRIATYASHSALQILKGAKDEGFETIAFGSSKVKPLYTKYFPVADYFIEEKYPEEELLNLNAVVVPTGSFVAHLGIELVENMKVPYFGNKRVLRWESDRNLERKWLKKAGIRVPEVYEDPDDIEKPVIVKPHGKGYFLAKDPEDFWRKAEKFLGIKRKEDLKNIQIQEYVLGVPVYPHYFYSKVREELELMSIDRRYESNVDAIGRIPAKDQLEFDMDITYTVIGNIPIVLRESLLMDVIEAGERVVKAAEELMGGLWGPFCLEGVFTPDLEFVVFEISARIVAGTNIFVNGSPYTWLRYDRPVSTGRRIAMEIREAIENDMLEKVLT 2r85 A 1.7 BS02 AMP A 2 S10 S71 A74 H75 S10 S71 A74 H75 6.3.4.23 0000287,0005524,0006164,0006188,0006189,0016874,0016879,0046872 Q8U0R7 18069798 401 MKVRIATYASHSALQILKGAKDEGFETIAFGSSKVKPLYTKYFPVADYFIEEKYPEEELLNLNAVVVPTGSFVAHLGIELVENMKVPYFGNKRVLRWESDRNLERKWLKKAGIRVPEVYEDPDDIEKPVIVKPHGKGYFLAKDPEDFWRKAEKFLGIKRKEDLKNIQIQEYVLGVPVYPHYFYSKVREELELMSIDRRYESNVDAIGRIPAKDQLEFDMDITYTVIGNIPIVLRESLLMDVIEAGERVVKAAEELMGGLWGPFCLEGVFTPDLEFVVFEISARIVAGTNIFVNGSPYTWLRYDRPVSTGRRIAMEIREAIENDMLEKVLT 2r85 B 1.7 BS01 AMP B 1 I130 K132 Y142 Y175 V176 Y227 F282 I130 K132 Y137 Y170 V171 Y222 F277 6.3.4.23 0000287,0005524,0006164,0006188,0006189,0016874,0016879,0046872 Q8U0R7 18069798 400 MKVRIATYASHSALQILKGAKDEGFETIAFGSSKVKPLYTKYFPVADYFIEEKYPEEELLNLNAVVVPTGSFVAHLGIELVENMKVPYFGNKRVLRWESDRNLERKWLKKAGIRVPEVYEDPDDIEKPVIVKPGKGYFLAKDPEDFWRKAEKFLGIKRKEDLKNIQIQEYVLGVPVYPHYFYSKVREELELMSIDRRYESNVDAIGRIPAKDQLEFDMDITYTVIGNIPIVLRESLLMDVIEAGERVVKAAEELMGGLWGPFCLEGVFTPDLEFVVFEISARIVAGTNIFVNGSPYTWLRYDRPVSTGRRIAMEIREAIENDMLEKVLT 2r85 B 1.7 BS02 AMP B 2 S10 S71 A74 H75 S10 S71 A74 H75 6.3.4.23 0000287,0005524,0006164,0006188,0006189,0016874,0016879,0046872 Q8U0R7 18069798 401 MKVRIATYASHSALQILKGAKDEGFETIAFGSSKVKPLYTKYFPVADYFIEEKYPEEELLNLNAVVVPTGSFVAHLGIELVENMKVPYFGNKRVLRWESDRNLERKWLKKAGIRVPEVYEDPDDIEKPVIVKPGKGYFLAKDPEDFWRKAEKFLGIKRKEDLKNIQIQEYVLGVPVYPHYFYSKVREELELMSIDRRYESNVDAIGRIPAKDQLEFDMDITYTVIGNIPIVLRESLLMDVIEAGERVVKAAEELMGGLWGPFCLEGVFTPDLEFVVFEISARIVAGTNIFVNGSPYTWLRYDRPVSTGRRIAMEIREAIENDMLEKVLT 2rh6 A 1.45 BS03 AMP A 1 T90 F91 L123 Y174 Y205 D210 E211 H214 H363 T47 F48 L80 Y131 Y162 D167 E168 H171 H320 433 TPHALLLISIDGLRADMLDRGITPNLSHLAREGVRARWMAPSYPSLTFPNHYTLVTGLRPDHHGIVHNSMRDPTLGGFWLSKSEAVGDARWWGGEPVWVGVENTGQHAATWSWPGSEAAIKGVRPSQWRHYQKGVRLDTRVDAVRGWLATDGAQRNRLVTLYFEHVDEAGHDHGPESRQYADAVRAVDAAIGRLLAGMQRDGTRARTNIIVVSDHGMAEVAPGHAISVEDIAPPQIATAITDGQVIGFEPLPGQQAAAEASVLGAHDHYDCWRKAELPARWQYGSHPRIPSLVCQMHEGWDALFPDKLAKRAQRGTRGSHGYDPALPSMRAVFLAQGPDLAQGKTLPGFDNVDVYALMSRLLGIPAAPNDGNPATLLPALRM 2rh6 B 1.45 BS03 AMP B 1 T90 F91 L123 Y174 Y205 D210 E211 H363 T47 F48 L80 Y131 Y162 D167 E168 H320 433 TPHALLLISIDGLRADMLDRGITPNLSHLAREGVRARWMAPSYPSLTFPNHYTLVTGLRPDHHGIVHNSMRDPTLGGFWLSKSEAVGDARWWGGEPVWVGVENTGQHAATWSWPGSEAAIKGVRPSQWRHYQKGVRLDTRVDAVRGWLATDGAQRNRLVTLYFEHVDEAGHDHGPESRQYADAVRAVDAAIGRLLAGMQRDGTRARTNIIVVSDHGMAEVAPGHAISVEDIAPPQIATAITDGQVIGFEPLPGQQAAAEASVLGAHDHYDCWRKAELPARWQYGSHPRIPSLVCQMHEGWDALFPDKLAKRAQRGTRGSHGYDPALPSMRAVFLAQGPDLAQGKTLPGFDNVDVYALMSRLLGIPAAPNDGNPATLLPALRM 2rh6 B 1.45 BS04 AMP B 2 S112 W122 F347 D349 S69 W79 F304 D306 434 TPHALLLISIDGLRADMLDRGITPNLSHLAREGVRARWMAPSYPSLTFPNHYTLVTGLRPDHHGIVHNSMRDPTLGGFWLSKSEAVGDARWWGGEPVWVGVENTGQHAATWSWPGSEAAIKGVRPSQWRHYQKGVRLDTRVDAVRGWLATDGAQRNRLVTLYFEHVDEAGHDHGPESRQYADAVRAVDAAIGRLLAGMQRDGTRARTNIIVVSDHGMAEVAPGHAISVEDIAPPQIATAITDGQVIGFEPLPGQQAAAEASVLGAHDHYDCWRKAELPARWQYGSHPRIPSLVCQMHEGWDALFPDKLAKRAQRGTRGSHGYDPALPSMRAVFLAQGPDLAQGKTLPGFDNVDVYALMSRLLGIPAAPNDGNPATLLPALRM 2rif A 2.35 BS01 AMP A 1 R10 P12 V13 V33 G34 H100 V113 S115 R117 D118 R9 P11 V12 V32 G33 H99 V112 S114 R116 D117 ? 0000166 Q8ZVX8 18513746 201 IRTSELLKRPPVSLPETATIREVATELAKNRVGLAVLTARDNPKRPVAVVSERDILRAVAQRLDLDGPAMPIANSPITVLDTDPVHVAAEKMRRHNIRHVVVVNKNGELVGVLSIRDLCFERAILLELATA 2rif A 2.35 BS02 AMP A 2 L35 V50 S52 D55 N75 I78 I98 R99 H100 L34 V49 S51 D54 N74 I77 I97 R98 H99 ? 0000166 Q8ZVX8 18513746 301 IRTSELLKRPPVSLPETATIREVATELAKNRVGLAVLTARDNPKRPVAVVSERDILRAVAQRLDLDGPAMPIANSPITVLDTDPVHVAAEKMRRHNIRHVVVVNKNGELVGVLSIRDLCFERAILLELATA 2rif B 2.35 BS01 AMP B 1 R10 P12 V13 G34 H100 V113 S115 R117 D118 R9 P11 V12 G33 H99 V112 S114 R116 D117 ? 0000166 Q8ZVX8 18513746 201 IRTSELLKRPPVSLPETATIREVATELAKNRVGLAVLTARDNPKRPVAVVSERDILRAVAQRLDLDGPAMPIANSPITVLDTDPVHVAAEKMRRHNIRHVVVVNKNGELVGVLSIRDLCFERAILLELA 2rif B 2.35 BS02 AMP B 2 V50 S52 R54 D55 N75 P77 I78 I98 R99 H100 V49 S51 R53 D54 N74 P76 I77 I97 R98 H99 ? 0000166 Q8ZVX8 18513746 301 IRTSELLKRPPVSLPETATIREVATELAKNRVGLAVLTARDNPKRPVAVVSERDILRAVAQRLDLDGPAMPIANSPITVLDTDPVHVAAEKMRRHNIRHVVVVNKNGELVGVLSIRDLCFERAILLELA 2rif C 2.35 BS01 AMP C 1 R10 P12 V13 V33 G34 H100 V113 S115 R117 D118 R9 P11 V12 V32 G33 H99 V112 S114 R116 D117 ? 0000166 Q8ZVX8 18513746 201 IRTSELLKRPPVSLPETATIREVATELAKNRVGLAVLTARDNPKRPVAVVSERDILRAVAQRLDLDGPAMPIANSPITVLDTDPVHVAAEKMRRHNIRHVVVVNKNGELVGVLSIRDLCFERAILLEL 2rif C 2.35 BS02 AMP C 2 L35 V50 S52 R54 D55 N75 I78 I98 R99 H100 L34 V49 S51 R53 D54 N74 I77 I97 R98 H99 ? 0000166 Q8ZVX8 18513746 301 IRTSELLKRPPVSLPETATIREVATELAKNRVGLAVLTARDNPKRPVAVVSERDILRAVAQRLDLDGPAMPIANSPITVLDTDPVHVAAEKMRRHNIRHVVVVNKNGELVGVLSIRDLCFERAILLEL 2rif D 2.35 BS01 AMP D 1 R10 P12 V13 G34 H100 V113 S115 R117 D118 R9 P11 V12 G33 H99 V112 S114 R116 D117 ? 0000166 Q8ZVX8 18513746 201 IRTSELLKRPPVSLPETATIREVATELAKNRVGLAVLTARDNPKRPVAVVSERDILRAVAQRLDLDGPAMPIANSPITVLDTDPVHVAAEKMRRHNIRHVVVVNKNGELVGVLSIRDLCFERAILLELAT 2rif D 2.35 BS02 AMP D 2 V50 S52 R54 D55 N75 P77 I78 I98 R99 H100 V49 S51 R53 D54 N74 P76 I77 I97 R98 H99 ? 0000166 Q8ZVX8 18513746 301 IRTSELLKRPPVSLPETATIREVATELAKNRVGLAVLTARDNPKRPVAVVSERDILRAVAQRLDLDGPAMPIANSPITVLDTDPVHVAAEKMRRHNIRHVVVVNKNGELVGVLSIRDLCFERAILLELAT 2uv4 A 1.33 BS01 AMP A 1 T200 I204 A205 S226 I312 S314 S316 D317 V323 T20 I24 A25 S46 I132 S134 S136 D137 V143 ? P54619 17452784 1324 HEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALV 2uv6 A 2.0 BS01 AMP A 1 T200 I204 A205 V225 S226 A227 I312 S314 S316 D317 V323 T20 I24 A25 V45 S46 A47 I132 S134 S136 D137 V143 ? P54619 17452784 1324 HEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHQLVVVDENDVVKGIVSLSDILQALV 2uv7 A 2.0 BS01 AMP A 1 T200 I204 A205 V225 S226 A227 I312 S314 S316 D317 V323 T20 I24 A25 V45 S46 A47 I132 S134 S136 D137 V143 ? P54619 17452784 1324 HEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHGLVVVDENDVVKGIVSLSDILQALV 2v8q E 2.1 BS01 AMP E 1 R69 K169 I239 S241 F243 D244 R268 F272 V275 L276 V296 H297 R298 R47 K147 I217 S219 F221 D222 R246 F250 V253 L254 V274 H275 R276 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 Kd=24.5uM P80385 17851531 1327 SNSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLTGG 2v8q E 2.1 BS02 AMP E 2 M84 T86 T88 D89 L128 V129 I149 H150 R151 M62 T64 T66 D67 L106 V107 I127 H128 R129 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 Kd=24.5uM P80385 17851531 1328 SNSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLTGG 2v8q E 2.1 BS03 AMP E 3 H150 T199 I203 A204 V224 S225 H297 I311 S313 S315 D316 H128 T177 I181 A182 V202 S203 H275 I289 S291 S293 D294 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 Kd=24.5uM P80385 17851531 1329 SNSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLTGG 2v92 E 2.4 BS03 AMP E 1 H150 T199 I203 A204 V224 S225 H297 I311 S313 D316 H128 T177 I181 A182 V202 S203 H275 I289 S291 D294 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 Kd=24.5uM P80385 17851531 1329 SNSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLTGG 2v9j E 2.53 BS03 AMP E 1 T199 I203 A204 V224 S225 H297 I311 S313 D316 T177 I181 A182 V202 S203 H275 I289 S291 D294 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 17851531 1329 SNSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLTGG 2var A 2.1 BS04 AMP A 1 G228 G231 M260 S285 I289 G227 G230 M259 S284 I288 G255 A256 G257 D258 G254 A255 G256 D257 2.7.1.178 0000166,0005524,0008671,0008673,0016301,0016310,0046835 Q97U29 19018105 1316 VDVIALGEPLIQFNSFNPGPLRFVNYFEKHVAGSELNFCIAVVRNHLSCSLIARVGNDEFGKNIIEYSRAQGIDTSHIKVDNESFTGIYFIQRGYPIPMKSELVYYRKGSAGSRLSPEDINENYVRNSRLVHSTGITLAISDNAKEAVIKAFELAKSRSLDTNIRPKLWSSLEKAKETILSILKKYDIEVLITDPDDTKILLDVTDPDEAYRKYKELGVKVLLYKLGSKGAIAYKDNVKAFKDAYKVPVEDPTGAGDAMAGTFVSLYLQGKDIEYSLAHGIAASTLVITVRGDNELTPTLEDAERFLNEFK 2var B 2.1 BS04 AMP B 1 K226 G228 G231 M260 S285 I289 K225 G227 G230 M259 S284 I288 G255 A256 G257 D258 G254 A255 G256 D257 2.7.1.178 0000166,0005524,0008671,0008673,0016301,0016310,0046835 Q97U29 19018105 1316 VDVIALGEPLIQFNSFNPGPLRFVNYFEKHVAGSELNFCIAVVRNHLSCSLIARVGNDEFGKNIIEYSRAQGIDTSHIKVDNESFTGIYFIQRGYPIPMKSELVYYRKGSAGSRLSPEDINENYVRNSRLVHSTGITLAISDNAKEAVIKAFELAKSRSLDTNIRPKLWSSLEKAKETILSILKKYDIEVLITDPDDTKILLDVTDPDEAYRKYKELGVKVLLYKLGSKGAIAYKDNVKAFKDAYKVPVEDPTGAGDAMAGTFVSLYLQGKDIEYSLAHGIAASTLVITVRGDNELTPTLEDAERFLNEFK 2var C 2.1 BS04 AMP C 1 G228 S229 A245 S285 G227 S228 A244 S284 G255 A256 G257 D258 G254 A255 G256 D257 2.7.1.178 0000166,0005524,0008671,0008673,0016301,0016310,0046835 Q97U29 19018105 1316 VDVIALGEPLIQFNSFNPGPLRFVNYFEKHVAGSELNFCIAVVRNHLSCSLIARVGNDEFGKNIIEYSRAQGIDTSHIKVDNESFTGIYFIQRGYPIPMKSELVYYRKGSAGSRLSPEDINENYVRNSRLVHSTGITLAISDNAKEAVIKAFELAKSRSLDTNIRPKLWSSLEKAKETILSILKKYDIEVLITDPDDTKILLDVTDPDEAYRKYKELGVKVLLYKLGSKGAIAYKDNVKAFKDAYKVPVEDPTGAGDAMAGTFVSLYLQGKDIEYSLAHGIAASTLVITVRGDNELTPTLEDAERFLNEFK 2vd6 A 2.0 BS01 AMP A 1 R85 H86 Q241 L331 S334 R338 R81 H82 Q237 L318 S321 R325 H86 T158 H159 K295 E302 H82 T154 H155 K282 E289 4.3.2.2 0001666,0003824,0004018,0005829,0006164,0006167,0006177,0006189,0007584,0009060,0009152,0009168,0014850,0016829,0032991,0042594,0042802,0044208,0044209,0070626,0097294 P30566 1000 GDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYES 2vd6 B 2.0 BS02 AMP C 1 R20 Y21 M299 R303 R16 Y17 M284 R288 H86 T158 H159 K295 E302 H82 T154 H155 K280 E287 4.3.2.2 0001666,0003824,0004018,0005829,0006164,0006167,0006177,0006189,0007584,0009060,0009152,0009168,0014850,0016829,0032991,0042594,0042802,0044208,0044209,0070626,0097294 P30566 1000 GDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVM 2vd6 C 2.0 BS02 AMP C 1 R85 H86 D87 Q241 R329 L331 S334 R338 R81 H82 D83 Q237 R314 L316 S319 R323 H86 T158 H159 K295 E302 H82 T154 H155 K280 E287 4.3.2.2 0001666,0003824,0004018,0005829,0006164,0006167,0006177,0006189,0007584,0009060,0009152,0009168,0014850,0016829,0032991,0042594,0042802,0044208,0044209,0070626,0097294 P30566 1000 GDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPY 2vd6 D 2.0 BS01 AMP A 1 R20 Y21 R303 R16 Y17 R289 H86 T158 H159 K295 E302 H82 T154 H155 K281 E288 4.3.2.2 0001666,0003824,0004018,0005829,0006164,0006167,0006177,0006189,0007584,0009060,0009152,0009168,0014850,0016829,0032991,0042594,0042802,0044208,0044209,0070626,0097294 P30566 1000 GDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVM 2vfk A 1.5 BS01 AMP A 1 T134 F179 R219 H224 T226 T47 F92 R132 H137 T139 Kd=194uM -logKd/Ki=3.71, Kd=194uM 18082768 1293 YQPNYFLSIPITNKKITAGIKVLQNSILRQDNRLTKAMVGDGSFHITLLVMQLLNEDEVNIGTDALLELKPFVEEILEGKHLTLPFHGIGTFQGQVGFVKLADGDHVSALLEIAETAKRTFQEKGILAGESRTFKPHLTFMKLSKAPMLWKKGVRKIEPGLYEQFIDHRFGEEILYQIDLCSMLKKKQSNGYYHCESSIVIGEKD 2vii A 2.85 BS01 AMP A 1 N7 L8 L9 G39 T40 G41 K42 L44 M189 I226 R227 N1 L2 L3 G33 T34 G35 K36 L38 M177 I214 R215 ? 0005524,0006355,0008134,0016887 P37344 18082766 260 NLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHEAQKRHPGRFERADGGTLFLDELATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGTFRADLLDRLAFDVVQLPPLRERESDIMLMAEYFAIQMCREIKLPLFPGFTERARETLLNYRWPGNIRELKNVVERSVYRHGTSDYPLDDIIIDPFKRRP 2vso A 2.6 BS01 AMP A 1 F42 Q49 G69 G71 K72 T73 F31 Q38 G58 G60 K61 T62 3.6.4.13 0002183,0003676,0003723,0003724,0003743,0004386,0005515,0005524,0005737,0005840,0005886,0006412,0006413,0006446,0008186,0010494,0016281,0016787,0016887,1901195 P10081 18606994 1394 QIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGLRDAQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIATL 2vso B 2.6 BS01 AMP B 1 F42 Q49 G69 G71 K72 T73 F31 Q38 G58 G60 K61 T62 3.6.4.13 0002183,0003676,0003723,0003724,0003743,0004386,0005515,0005524,0005737,0005840,0005886,0006412,0006413,0006446,0008186,0010494,0016281,0016787,0016887,1901195 P10081 18606994 1394 QIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGLRDAQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIATL 2vsx A 2.8 BS01 AMP A 1 F42 Q49 G69 G71 K72 T73 F31 Q38 G58 G60 K61 T62 3.6.4.13 0002183,0003676,0003723,0003724,0003743,0004386,0005515,0005524,0005737,0005840,0005886,0006412,0006413,0006446,0008186,0010494,0016281,0016787,0016887,1901195 P10081 18606994 1178 QIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGLRDAQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIATL 2vsx B 2.8 BS01 AMP B 1 F42 Q49 G69 G71 K72 T73 F31 Q38 G58 G60 K61 T62 3.6.4.13 0002183,0003676,0003723,0003724,0003743,0004386,0005515,0005524,0005737,0005840,0005886,0006412,0006413,0006446,0008186,0010494,0016281,0016787,0016887,1901195 P10081 18606994 1178 QIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGLRDAQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIATL 2vze A 2.45 BS01 AMP A 1 W265 G338 E339 S340 E359 Y361 G362 Q363 T364 D446 F458 R461 R472 W229 G302 E303 S304 E323 Y325 G326 Q327 T328 D410 F422 R425 R436 T221 T364 E365 N467 R472 K557 T185 T328 E329 N431 R436 K521 6.2.1.2,6.2.1.25 0004321,0005524,0005739,0005759,0006631,0006633,0006637,0015645,0016874,0018858,0031956,0036112,0042593,0046872,0070328,0102391 Q08AH3 19345228 1570 HQEVPAKFNFASDVLDHWADMEKAGKRPPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKEWK 2vze B 2.45 BS01 AMP B 1 G338 E339 S340 E359 Y361 G362 Q363 T364 D446 F458 R461 R472 G302 E303 S304 E323 Y325 G326 Q327 T328 D410 F422 R425 R436 T221 T364 E365 N467 R472 K557 T185 T328 E329 N431 R436 K521 6.2.1.2,6.2.1.25 0004321,0005524,0005739,0005759,0006631,0006633,0006637,0015645,0016874,0018858,0031956,0036112,0042593,0046872,0070328,0102391 Q08AH3 19345228 1570 HQEVPAKFNFASDVLDHWADMEKAGKRPPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKEWK 2vze C 2.45 BS02 AMP C 1 G338 E339 S340 Y361 G362 Q363 T364 D446 F458 R461 R472 G305 E306 S307 Y328 G329 Q330 T331 D413 F425 R428 R439 T221 T364 E365 N467 R472 K557 T188 T331 E332 N434 R439 K524 6.2.1.2,6.2.1.25 0004321,0005524,0005739,0005759,0006631,0006633,0006637,0015645,0016874,0018858,0031956,0036112,0042593,0046872,0070328,0102391 Q08AH3 19345228 1571 QWGHQEVPAKFNFASDVLDHWADMEKAGKRPPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKEWK 2w4y A 2.9 BS03 AMP A 1 E31 Y33 R42 E31 Y33 R42 19559027 1125 ALGDTLTITLGGSGGTAKVLRKINQDGYTSEYYLPETSSSFRAKVRHTKESVKPNQVQYERHNVEFTETVYASGSTPEFVRQAYVVIRHKVGDVSATVSDLGEALSFYLNEALYGKLIGWES 2w4y A 2.9 BS04 AMP B 1 Y28 K49 Y28 K49 19559027 1124 ALGDTLTITLGGSGGTAKVLRKINQDGYTSEYYLPETSSSFRAKVRHTKESVKPNQVQYERHNVEFTETVYASGSTPEFVRQAYVVIRHKVGDVSATVSDLGEALSFYLNEALYGKLIGWES 2w4y B 2.9 BS03 AMP B 1 I23 E31 Y33 R42 I23 E31 Y33 R42 19559027 1124 ALGDTLTITLGGSGGTAKVLRKINQDGYTSEYYLPETSSSFRAKVRHTKESVKPNQVQYERHNVEFTETVYASGSTPEFVRQAYVVIRHKVGDVSATVSDLGEALSFYLNEALYGKLIGWES 2w4y C 2.9 BS02 AMP A 1 Y28 H47 T48 K49 Y28 H47 T48 K49 19559027 1125 ALGDTLTITLGGSGGTAKVLRKINQDGYTSEYYLPETSSSFRAKVRHTKESVKPNQVQYERHNVEFTETVYASGSTPEFVRQAYVVIRHKVGDVSATVSDLGEALSFYLNEALYGKLIGWES 2w4y C 2.9 BS03 AMP B 2 Y33 R42 Y33 R42 19559027 1125 ALGDTLTITLGGSGGTAKVLRKINQDGYTSEYYLPETSSSFRAKVRHTKESVKPNQVQYERHNVEFTETVYASGSTPEFVRQAYVVIRHKVGDVSATVSDLGEALSFYLNEALYGKLIGWES 2w4z A 3.6 BS02 AMP A 1 Y28 H47 T48 K49 E60 Y28 H47 T48 K49 E60 19559027 1124 ALGDTLTITLGGSGGTAKVLRKINQDGYTSEYYLPETSSSFRAKVRHTKESVKPNQVQYERHNVEFTETVYASGSTPEFVRQAYVVIRHKVGDVSATVSDLGEALSFYLNEALYGKLIGWES 2w4z A 3.6 BS04 AMP C 1 Y33 R42 Y33 R42 19559027 1125 ALGDTLTITLGGSGGTAKVLRKINQDGYTSEYYLPETSSSFRAKVRHTKESVKPNQVQYERHNVEFTETVYASGSTPEFVRQAYVVIRHKVGDVSATVSDLGEALSFYLNEALYGKLIGWES 2w4z B 3.6 BS01 AMP A 1 E31 Y33 R42 E31 Y33 R42 19559027 1124 ALGDTLTITLGGSGGTAKVLRKINQDGYTSEYYLPETSSSFRAKVRHTKESVKPNQVQYERHNVEFTETVYASGSTPEFVRQAYVVIRHKVGDVSATVSDLGEALSFYLNEALYGKLIGWES 2w4z B 3.6 BS03 AMP B 1 Y28 K49 Y28 K49 19559027 1124 ALGDTLTITLGGSGGTAKVLRKINQDGYTSEYYLPETSSSFRAKVRHTKESVKPNQVQYERHNVEFTETVYASGSTPEFVRQAYVVIRHKVGDVSATVSDLGEALSFYLNEALYGKLIGWES 2w4z C 3.6 BS01 AMP B 1 Y33 R42 Y33 R42 19559027 1124 ALGDTLTITLGGSGGTAKVLRKINQDGYTSEYYLPETSSSFRAKVRHTKESVKPNQVQYERHNVEFTETVYASGSTPEFVRQAYVVIRHKVGDVSATVSDLGEALSFYLNEALYGKLIGWES 2w4z C 3.6 BS04 AMP C 1 Y28 H47 T48 K49 Y28 H47 T48 K49 19559027 1125 ALGDTLTITLGGSGGTAKVLRKINQDGYTSEYYLPETSSSFRAKVRHTKESVKPNQVQYERHNVEFTETVYASGSTPEFVRQAYVVIRHKVGDVSATVSDLGEALSFYLNEALYGKLIGWES 2wef A 1.8 BS03 AMP A 1 D120 T195 H198 G219 G220 K224 F238 G242 C243 D247 D115 T190 H193 G214 G215 K219 F233 G237 C238 D242 D51 E74 D117 L119 D120 T122 D247 D46 E69 D112 L114 D115 T117 D242 3.1.3.57,3.1.3.7 0004441,0005739,0005829,0006139,0007399,0008441,0016787,0046854,0046872,0050427 O95861 601 TVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPESIKNALVP 2x3k A 2.5 BS01 AMP A 1 H170 R305 H444 Q446 N509 H163 R298 H437 Q439 N502 ? 0005524,0009058,0016881,0019290,0046872 Q93AT8 1588 DVLSRMISEKAALHGLLNCLIKEFAIPEGYLRYEWPDEMKGIPPGAYFDGADWKGIPMMIGLPDQLQLFVMVDRRDTFGSQHYLSDVYLRQAGDWQCPDFEPLVARLLAACEHIAGRKNPELYEQILQSQRLVSAIVSHNGRQRADAPLQHYLQSEQGLWFGHPSHPAPKARLWPAHLGQEQWAPEFQARAALHQFEVPVDGLHIGANGLTPQQVLDGFADQQPASPGHAIICMHPVQAQLFMQDARVQQLLRDNVIRDLGQSGRVASPTASIRTWFIDDHDYFIKGSLNVRITNCVRKNAWYELESTVLIDRLFRQLLDQHADTLGGLVAAAEPGVVSWSPAAAGELDSHWFREQTGGILRENFCRRTGAERSIMAGTLFARGVDLQPMIQTFLRTHYGEALDDNALLYWFDDYQTRLLRPVLSLFFNHGVVMEPHLQNSVLVHQQGRPQQVLLRDFEGVKLTDDLGIRYIDDDIHPRVRQSLLYSREQGWNRIMYCLFINHLSETILALSQGRPQLAPLMWRRVQQQLRAIQGELKQPSPELDALIAGHPVACKTNLKVRLAAASYVRLPSPW 2x3k B 2.5 BS01 AMP B 1 L166 H170 R305 H444 Q446 N509 L158 H162 R297 H436 Q438 N497 ? 0005524,0009058,0016881,0019290,0046872 Q93AT8 1588 DVLSRMISEKAALHGLLNCLIKEFAIPEGYLRYEWPDEMKGIPPGAYFDGADWKGIPMMIGLPDQLQLFVMVDRRDTFGSQHYLSDVYLRQGDWQCPDFEPLVARLLAACEHIAGRKNPELYEQILQSQRLVSAIVSHNGRQRADAPLQHYLQSEQGLWFGHPSHPAPKARLWPAHLGQEQWAPEFQARAALHQFEVPVDGLHIGANGLTPQQVLDGFADQQPASPGHAIICMHPVQAQLFMQDARVQQLLRDNVIRDLGQSGRVASPTASIRTWFIDDHDYFIKGSLNVRITNCVRKNAWYELESTVLIDRLFRQLLDQHADTLGGLVAAAEPGVVSWSPAAAGELDSHWFREQTGGILRENFCRRTGAERSIMAGTLFARGVDLQPMIQTFLRTHYGEALDDNALLYWFDDYQTRLLRPVLSLFFNHGVVMEPHLQNSVLVHQQGRPQQVLLRDFEGVKLTDDLGIRYIHPRVRQSLLYSREQGWNRIMYCLFINHLSETILALSQGRPQLAPLMWRRVQQQLRAIQGELKQPSPELDALIAGHPVACKTNLKVRLAAASYVRLPSPW 2x75 A 2.5 BS01 AMP A 1 R4 Y5 N276 R3 Y4 N275 H68 T140 H141 S262 S263 K268 E275 H67 T139 H140 S261 S262 K267 E274 4.3.2.2 0003824,0004018,0005829,0006164,0006189,0009152,0009168,0016829,0044208,0070626 Q7A0G9 20693687 1433 IERYSREEMSNIWTDQNRYEAWLEVEILACEAWSELGHIPKADVQKIRQNAKVNVERAQEIEQETRHDVVAFTRQVSETLGEERKWVHYGLTSTDVVDTALSFVIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTFGVKMALWYTEMQRNLQRFKQVREEIEVGKMSGAVGTFANIPPEIESYVCKHLGIGTAPVSTQTLQRDRHAYYIATLALIATSLEKFAVEIRNLQKTETREVEEAFAKGQKGSSAMPHKRNPIGSENITGISRVIRGYITTAYENVPLWHERDISHSSAERIMLPDVTIALDYALNRFTNIVDRLTVFEDNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDKVQPKAMISWETKTPFRELIEQDESITTKEELDECFDPKHHLNQVDTIFERAGLA 2xoy B 2.6 BS06 AMP B 1 W637 C641 R642 R661 K663 N664 W187 C191 R192 R211 K213 N214 2.3.2.27 Q96EP1 20880844 1665 YVVCRQCPEYRRQAAQPPHCPADYVCPLQGSHALCTCCFQPMPDRRVEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTVLCYCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFKN 2xoz B 2.374 BS06 AMP B 1 C635 Y636 F653 C184 Y185 F202 2.3.2.27 Q96EP1 20880844 1664 YVVCRQCPEYRRQAAQPPHCPDYVCPLQGSHALCTCCFQPMPDRRVEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTVLCYCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFK 2xoz B 2.374 BS07 AMP B 2 W637 C641 R642 T643 W186 C190 R191 T192 2.3.2.27 Q96EP1 20880844 1665 YVVCRQCPEYRRQAAQPPHCPDYVCPLQGSHALCTCCFQPMPDRRVEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTVLCYCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFK 2xxb A 2.15 BS01 AMP A 1 G28 G30 M31 D53 L54 Y85 A98 G99 G7 G9 M10 D32 L33 Y62 A75 G76 R109 D168 R171 H195 R85 D145 R148 H172 1.1.1.27 0003824,0004459,0005737,0006089,0006090,0006096,0016491,0016616,0019752 Q5SJA1 1332 MKVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDILHATPFAHPVWVWAGSYGDLEGARAVVLAAGVAQRPGETRLQLLDRNAQVFAQVVPRVLEAAPEAVLLVATNPVDVMTQVAYALSGLPPGRVVGSGTILDTARFRALLAEYLRVAPQSVHAYVLGEHGDSEVLVWSSAQVGGVPLLEFAEARGRALSPEDRARIDEGVRRAAYRIIEGKGATYYGIGAGLARLVRAILTDEKGVYTVSAFTPEVAGVLEVSLSLPRILGAGGVAGTVYPSLSPEERAALRRSAEILKEAAFALGF 2xxb B 2.15 BS01 AMP B 1 G30 M31 V32 D53 L54 A98 G99 V123 G9 M10 V11 D32 L33 A75 G76 V99 R109 D168 R171 H195 R85 D145 R148 H172 1.1.1.27 0003824,0004459,0005737,0006089,0006090,0006096,0016491,0016616,0019752 Q5SJA1 1332 MKVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDILHATPFAHPVWVWAGSYGDLEGARAVVLAAGVAQRPGETRLQLLDRNAQVFAQVVPRVLEAAPEAVLLVATNPVDVMTQVAYALSGLPPGRVVGSGTILDTARFRALLAEYLRVAPQSVHAYVLGEHGDSEVLVWSSAQVGGVPLLEFAEARGRALSPEDRARIDEGVRRAAYRIIEGKGATYYGIGAGLARLVRAILTDEKGVYTVSAFTPEVAGVLEVSLSLPRILGAGGVAGTVYPSLSPEERAALRRSAEILKEAAFALGF 2y8l E 2.5 BS03 AMP E 1 T199 I203 A204 V224 S225 H297 I311 S313 D316 T177 I181 A182 V202 S203 H275 I289 S291 D294 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 21399626 1329 SNSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLTGG 2y8q E 2.8 BS02 AMP E 1 T199 I203 A204 V224 S225 I311 S313 D316 T177 I181 A182 V202 S203 I289 S291 D294 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 21399626 1328 SNSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLTGG 2ya3 E 2.51 BS03 AMP E 1 T199 I203 A204 V224 S225 H297 I311 S313 S315 D316 T175 I179 A180 V200 S201 H273 I287 S289 S291 D292 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 21399626 1327 SSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLT 2yab A 1.9 BS01 AMP A 1 G20 S21 V27 A40 K42 V96 I160 D161 G18 S19 V25 A38 K40 V94 I158 D159 D139 K141 E143 N144 D161 T180 D137 K139 E141 N142 D159 T178 2.7.11.1 0004672,0004674,0005516,0005524,0005737,0006338,0006468,0006915,0016310,0031410,0034423,0035556,0044024,0106310,1990266,2001242 Q8VDF3 21497605 1302 TFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDTQQAMVRRESVVNLENFKKQYV 2yab B 1.9 BS01 AMP B 1 G20 V27 A40 K42 V96 D161 G18 V25 A38 K40 V94 D159 D139 K141 E143 N144 D161 T180 D137 K139 E141 N142 D159 T178 2.7.11.1 0004672,0004674,0005516,0005524,0005737,0006338,0006468,0006915,0016310,0031410,0034423,0035556,0044024,0106310,1990266,2001242 Q8VDF3 21497605 1302 TFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDTQQAMVRRESVVNLENFKKQYV 2yb1 A 1.898 BS04 AMP A 1 H39 R99 R102 S133 R134 T135 F154 H38 R98 R101 S132 R133 T134 F153 3.1.3.97 0000166,0003824,0004534,0006259,0016311,0016787,0030145,0035312,0046872,0097657 Q7NXD4 24401123 1292 ANIDLHFHSRTSDGALTPTEVIDRAAARAPALLALTDHDCTGGLAEAAAAAARRGIPFLNGVEVSVSWGRHTVHIVGLGIDPAEPALAAGLKSIREGRLERARQMGASLEAAGIAGCFDGAMRWCDNPEMISRTHFARHLVDSGAVKDMRTVFRKYLTPGKPGYVSHQWASLEDAVGWIVGAGGMAVIAHPGRYDMGRTLIERLILDFQAAGGQGIEVASGSHSLDDMHKFALHADRHGLYASSGSDFHAPGEDVGHTEDLPPICRPIWRELEARILRPADAEN 2yj4 A 2.4 BS01 AMP A 1 E445 H450 I479 G480 K494 I501 E61 H66 I95 G96 K110 I115 N416 N32 3.6.3.10 0000166,0005215,0005524,0016020,0016887 Q97UU7 1635 LSLYEKMLHKGMIIKNSNVYEKIKEIDTIIFNKTGTLTYGTPIVTQFIGDSLSLAYAASVEALSSHPIAKAIVKYAKEQGVKILEVKDFKEISGIGVRGKISDKIIEVKKAENDIAVYINGEPIASFNISDVPRPNLKDYLEKLKNEGLKIIILSGDKEDKVKELSKELNIQEYYSNLSPEDKVRIIEKLKQNGNKVLMIGDGVNDAAALALADVSVAMGNGVDISKNVADIILVSNDIGTLLGLIKN 2yrx A 1.9 BS02 AMP A 1 E186 L188 E192 K214 E189 L191 E195 K217 6.3.4.13 0003824,0004637,0005524,0006164,0006189,0009113,0016874,0046872 Q5L3C7 20716513 500 NLYFQSHMNVLVIGRGGREHAIAWKAAQSPLVGKLYVAPGNPGIADVAELVHIDELDIEALVQFAKQQAIDLTIVGPEAPLASGIVDRFMAEGLRIFGPSQRAALIEGSKAFAKELMKKYGIPTADHAAFTSYEEAKAYIEQKGAPIVIKADGKGVTVAQTVEEALAAAKAALVDGQFGTAGSQVVIEEYLEGEEFSFMAFVNGEKVYPLAIAQDHKRAYDGDEGPNTGGMGAYSPVPQISDEMMDAALEAILRPAAKALAAEGRPFLGVLYAGLMATANGPKVIEFNARFGDPEAQVVLPRLKTDLVEAVLAVMDGKELELEWTDEAVLGVVLAAKGYPGAYERGAEIRGLDRISPDALLFHAGTKREGGAWYTNGGRVLLLAAKGETLAKAKEKAYEQLAAIDCDGLFYRRDIGRRAI 2ys6 A 2.21 BS02 AMP A 1 E192 K214 I282 E195 K217 I285 6.3.4.13 0003824,0004637,0005524,0006164,0006189,0009113,0016874,0046872 Q5L3C7 20716513 432 NLYFQSHMNVLVIGRGGREHAIAWKAAQSPLVGKLYVAPGNPGIADVAELVHIDELDIEALVQFAKQQAIDLTIVGPEAPLASGIVDRFMAEGLRIFGPSQRAALIEGSKAFAKELMKKYGIPTADHAAFTSYEEAKAYIEQKGAPIVIKADGKGVTVAQTVEEALAAAKAALVDGQFGTAGSQVVIEEYLEGEEFSFMAFVNGEKVYPLAIAQDHKRAYDGDEGPNTGGMGAYSPVPQISDEMMDAALEAILRPAAKALAAEGRPFLGVLYAGLMATANGPKVIEFNARFGDPEAQVVLPRLKTDLVEAVLAVMDGKELELEWTDEAVLGVVLAAKGYPGAYERGAEIRGLDRISPDALLFHAGTKREGGAWYTNGGRVLLLAAKGETLAKAKEKAYEQLAAIDCDGLFYRRDIGRRAIE 2yvo A 1.67 BS03 AMP A 1 V17 G75 E90 E136 G138 E139 V17 G75 E90 E136 G138 E139 R62 A74 E90 E94 E137 R62 A74 E90 E94 E137 3.6.1.- 0000166,0005829,0006753,0016462,0016787,0019693,0046872 Q5SJY9 18039767 2001 MSPWERILLEEILSEPVRLVKERVRTHTGRELTYVYRPGPVAASFVLPVTERGTALLVRQYRHPTGKFLLEVPAGKVDEGETPEAAARRELREEVGAEAETLIPLPSFHPQPSFTAVVFHPFLALKARVVTPPTLEEGELLESLELPLTEVYALLAKGEIQDASTALTLFYAEPHLKRLGLL 2ze5 A 2.31 BS01 AMP A 1 D33 R34 V35 S45 S99 I100 S101 D171 I172 D173 H214 D33 R34 V35 S45 S99 I100 S101 D171 I172 D173 H214 2.5.1.27 0005515,0009691,0009824,0016740 P58758 18258747 401 MLLHLIYGPTCSGKTDMAIQIAQETGWPVVALDRVQCCPQIATGSGRPLESELQSTRRIYLDSRPLTEGILDAESAHRRLIFEVDWRKSEEGLILEGGSISLLNCMAKSPFWRSGFQWHVKRLRLGDSDAFLTRAKQRVAEMFAIREDRPSLLEELAELWNYPAARPILEDIDGYRCAIRFARKHDLAISQLPNIDAGRHVELIEAIANEYLEHALSQERDFPQWPE 2ze6 A 2.1 BS02 AMP A 1 D33 R34 V35 S45 S99 I100 S101 D171 I172 D173 H214 D33 R34 V35 S45 S99 I100 S101 D171 I172 D173 H214 2.5.1.27 0005515,0009691,0009824,0016740 P58758 18258747 401 MLLHLIYGPTCSGKTDMAIQIAQETGWPVVALDRVQCCPQIATGSGRPLESELQSTRRIYLDSRPLTEGILDAESAHRRLIFEVDWRKSEEGLILEGGSISLLNCMAKSPFWRSGFQWHVKRLRLGDSDAFLTRAKQRVAEMFAIREDRPSLLEELAELWNYPAARPILEDIDGYRCAIRFARKHDLAISQLPNIDAGRHVELIEAIANEYLEHALSQERDFPQWPE 2ze7 A 2.1 BS03 AMP A 1 D33 R34 V35 S45 S99 I100 S101 D171 I172 D173 H214 D33 R34 V35 S45 S99 I100 S101 D171 I172 D173 H214 2.5.1.27 0005515,0009691,0009824,0016740 P58758 18258747 401 MLLHLIYGPTCSGKTDMAIQIAQETGWPVVALDRVQCCPQIATGSGRPLESELQSTRRIYLDSRPLTEGILDAESAHRRLIFEVDWRKSEEGLILEGGSISLLNCMAKSPFWRSGFQWHVKRLRLGDSDAFLTRAKQRVAEMFAIREDRPSLLEELAELWNYPAARPILEDIDGYRCAIRFARKHDLAISQLPNIDAGRHVELIEAIANEYLEHALSQERDFPQWP 2zr2 A 2.8 BS01 AMP A 1 R283 E285 F297 R298 V299 F302 E370 V371 V372 T406 A409 S411 R412 R283 E285 F297 R298 V299 F302 E370 V371 V372 T406 A409 S411 R412 R283 R298 E370 S373 R412 R283 R298 E370 S373 R412 6.1.1.11 0000049,0000166,0004812,0004828,0005524,0005737,0005829,0006412,0006418,0006434,0016260 O58441 18818520 1001 MLDIKLIRENPELVKNDLIKRGELEKVKWVDEILKLDTEWRTKLKEINRLRHERNKIAVEIGKRRKKGEPVDELLAKSREIVKRIGELENEVEELKKKIDYYLWRLPNITHPSVPVGKDENDNVPIRFWGKARVWKGHLERFLEQSQGKMEYEILEWKPKLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDRLIEKGFTPVIPPYMVRRFVEEGSTSFEDFEDVIYKVEDEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGVSPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHEKIIRNAEELFQELEIPYRVVNICTGDLGYVAAKKYDIEAWMPGQGKFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEDGTVRIPKVLWKYTGFKEIVPVE 2zr2 B 2.8 BS01 AMP B 1 R283 E285 F297 R298 V299 F302 E370 V371 A409 S411 R412 R283 E285 F297 R298 V299 F302 E370 V371 A409 S411 R412 R283 R298 E370 S373 R412 R283 R298 E370 S373 R412 6.1.1.11 0000049,0000166,0004812,0004828,0005524,0005737,0005829,0006412,0006418,0006434,0016260 O58441 18818520 1002 MLDIKLIRENPELVKNDLIKRGELEKVKWVDEILKLDTEWRTKLKEINRLRHERNKIAVEIGKRRKKGEPVDELLAKSREIVKRIGELENEVEELKKKIDYYLWRLPNITHPSVPVGKDENDNVPIRFWGKARVWKGHLERFLEQSQGKMEYEILEWKPKLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDRLIEKGFTPVIPPYMVRRFVEEGSTSFEDFEDVIYKVEDEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGVSPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHEKIIRNAEELFQELEIPYRVVNICTGDLGYVAAKKYDIEAWMPGQGKFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEDGTVRIPKVLWKYTGFKEIVPVE 3a7a A 3.1 BS01 AMP A 1 G75 V77 F78 K133 T151 L153 V180 R181 S182 V184 G75 V77 F78 K133 T151 L153 V180 R181 S182 V184 6.3.1.20 0005524,0005737,0005829,0009249,0016874,0016979,0017118,0036211 P32099 20089862 402 STLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTVEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITEAFFAHYGERVEAEIISPNKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPEQEKELRELSAWMAGAVR 3a7a C 3.1 BS01 AMP C 1 G75 A76 V77 F78 K133 T151 L153 L161 S182 G75 A76 V77 F78 K133 T151 L153 L161 S182 6.3.1.20 0005524,0005737,0005829,0009249,0016874,0016979,0017118,0036211 P32099 20089862 402 STLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTVEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITEAFFAHYGERVEAEIISPNKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPEQEKELRELSAWMAGAVR 3a9v A 2.5 BS01 AMP A 1 H234 G306 A307 P308 Y330 G331 M332 T333 D417 K434 K438 Q443 H230 G302 A303 P304 Y326 G327 M328 T329 D413 K430 K434 Q439 S186 S206 H234 T333 E334 K438 Q443 K523 S182 S202 H230 T329 E330 K434 Q439 K519 6.2.1.12 0000166,0003824,0016405,0016874 Q941M3 20841425 551 EEFIFRSKLPDIYIPKNLPLHSYVLENLSNHSSKPCLINGANGDVYTYADVELTARRVASGLNKIGIQQGDVIMLFLPSSPEFVLAFLGASHRGAIITAANPFSTPAELAKHAKASRAKLLITQACYYEKVKDFARESDVKVMCVDSAPDGCLHFSELTQADENEAPQVDISPDDVVALPYSSGTTGLPKGVMLTHKGLITSVAQQVDGDNPNLYFHSEDVILCVLPMFHIYALNSIMLCGLRVGAPILIMPKFEIGSLLGLIEKYKVSIAPVVPPVMMSIAKSPDLDKHDLSSLRMIKSGGAPLGKELEDTVRAKFPQARLGQGYGMTEAGPVLAMCLAFAKEPFDIKPGACGTVVRNAEMKIVDPETGASLPRNQPGEICIRGDQIMKGYLNDPEATSRTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIAHPEISDAAVVGLKDEDAGEVPVAFVVKSEKSQATEDEIKQYISKQVIFYKRIKRVFFIEAIPKAPSGKILRKNLKEK 3aw8 A 2.6 BS01 AMP A 1 L135 K137 Q148 F174 V175 E180 H203 F248 E258 L135 K137 Q142 F168 V169 E174 H197 F242 E252 E246 E258 N265 S266 K335 E240 E252 N259 S260 K329 6.3.4.18 0004638,0005524,0006164,0006189,0016874,0034028,0046872 Q5SKY0 370 MIGILGGGQLGRMLALAGYPLGLSFRFLDPSPEACAGQVGELVVGEFLDEGALLRFAEGLALVTYEFENVPVEAARRLEGRLPLYPPAKALEVAQDRLREKTFFQGLGVPTPPFHPVDGPEDLEEGLKRVGLPALLKTRRGQALVRTEEEALEALKALGGRGLILEGFVPFDREVSLLAVRGRTGEVAFYPLVENRHWGGILRLSLAPAPGASEALQKKAEAYALRAMEALDYVGVLALEFFQVGEELLFNEMAPRVHNSGHWTIEGAETSQFENHLRAVLGLPLGSTAPRGQSAMVNLIGEKPPFAEVLKVEGAHLHWYGKAVRPGRKVGHITLRRDGLKALEEGLARLSRLVSELPWE 3aw8 B 2.6 BS01 AMP B 1 R97 L135 K137 Q148 F174 V175 F248 R97 L135 K137 Q142 F168 V169 F242 E246 E258 N265 S266 K335 E240 E252 N259 S260 K329 6.3.4.18 0004638,0005524,0006164,0006189,0016874,0034028,0046872 Q5SKY0 370 MIGILGGGQLGRMLALAGYPLGLSFRFLDPSPEACAGQVGELVVGEFLDEGALLRFAEGLALVTYEFENVPVEAARRLEGRLPLYPPAKALEVAQDRLREKTFFQGLGVPTPPFHPVDGPEDLEEGLKRVGLPALLKTRRGQALVRTEEEALEALKALGGRGLILEGFVPFDREVSLLAVRGRTGEVAFYPLVENRHWGGILRLSLAPAPGASEALQKKAEAYALRAMEALDYVGVLALEFFQVGEELLFNEMAPRVHNSGHWTIEGAETSQFENHLRAVLGLPLGSTAPRGQSAMVNLIGEKPPFAEVLKVEGAHLHWYGKAVRPGRKVGHITLRRDGLKALEEGLARLSRLVSELPWE 3b1r A 2.0 BS01 AMP A 1 S8 D12 G48 C49 F117 P143 Q169 G250 D253 S7 D11 G47 C48 F116 P142 Q168 G249 D252 D247 P248 G250 C251 D246 P247 G249 C250 2.7.1.143 0000166,0016301,0016310,0016772 Q2SZE4 22101821 501 ATLICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIASRVQALIITRGEHGATIRHRDGTEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEIDARFETAFGYRP 3b1r A 2.0 BS02 AMP A 2 N111 T220 G222 E223 G225 C251 F255 S277 G280 I284 N110 T219 G221 E222 G224 C250 F254 S276 G279 I283 D247 P248 G250 C251 D246 P247 G249 C250 2.7.1.143 0000166,0016301,0016310,0016772 Q2SZE4 22101821 502 ATLICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIASRVQALIITRGEHGATIRHRDGTEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEIDARFETAFGYRP 3b1r B 2.0 BS01 AMP B 1 S8 D12 G48 C49 F117 M122 Q169 G250 D253 S7 D11 G47 C48 F116 M121 Q168 G249 D252 D247 P248 G250 C251 D246 P247 G249 C250 2.7.1.143 0000166,0016301,0016310,0016772 Q2SZE4 22101821 501 ATLICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIASRVQALIITRGEHGATIRHRDGTEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEIDARFETAFGYRP 3b1r B 2.0 BS02 AMP B 2 N111 T220 G222 E223 G225 S277 G280 I284 N110 T219 G221 E222 G224 S276 G279 I283 D247 P248 G250 C251 D246 P247 G249 C250 2.7.1.143 0000166,0016301,0016310,0016772 Q2SZE4 22101821 502 ATLICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIASRVQALIITRGEHGATIRHRDGTEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEIDARFETAFGYRP 3b1r C 2.0 BS01 AMP C 1 S8 D12 G48 C49 N52 Q113 F117 M122 Q169 G250 D253 S7 D11 G47 C48 N51 Q112 F116 M121 Q168 G249 D252 D247 P248 G250 C251 D246 P247 G249 C250 2.7.1.143 0000166,0016301,0016310,0016772 Q2SZE4 22101821 501 ATLICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIASRVQALIITRGEHGATIRHRDGTEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEIDARFETAFGYRP 3b1r C 2.0 BS02 AMP C 2 T220 G222 G225 C251 F255 S277 G280 I284 T219 G221 G224 C250 F254 S276 G279 I283 D247 P248 G250 C251 D246 P247 G249 C250 2.7.1.143 0000166,0016301,0016310,0016772 Q2SZE4 22101821 502 ATLICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIASRVQALIITRGEHGATIRHRDGTEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEIDARFETAFGYRP 3b1r D 2.0 BS01 AMP D 1 S8 D12 G47 G48 C49 N52 Q113 F117 Q169 G250 D253 S7 D11 G46 G47 C48 N51 Q112 F116 Q168 G249 D252 D247 P248 G250 C251 D246 P247 G249 C250 2.7.1.143 0000166,0016301,0016310,0016772 Q2SZE4 22101821 501 ATLICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIASRVQALIITRGEHGATIRHRDGTEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEIDARFETAFGYRP 3b1r D 2.0 BS02 AMP D 2 T220 G222 G225 C251 G252 S277 I284 T219 G221 G224 C250 G251 S276 I283 D247 P248 G250 C251 D246 P247 G249 C250 2.7.1.143 0000166,0016301,0016310,0016772 Q2SZE4 22101821 502 ATLICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIASRVQALIITRGEHGATIRHRDGTEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEIDARFETAFGYRP 3b1r E 2.0 BS01 AMP E 1 S8 D12 G47 G48 C49 N52 F117 M122 Q169 G250 D253 S7 D11 G46 G47 C48 N51 F116 M121 Q168 G249 D252 D247 P248 G250 C251 D246 P247 G249 C250 2.7.1.143 0000166,0016301,0016310,0016772 Q2SZE4 22101821 501 ATLICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIASRVQALIITRGEHGATIRHRDGTEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEIDARFETAFGYRP 3b1r E 2.0 BS02 AMP E 2 N111 T220 G222 E223 G225 S277 I284 N110 T219 G221 E222 G224 S276 I283 D247 P248 G250 C251 D246 P247 G249 C250 2.7.1.143 0000166,0016301,0016310,0016772 Q2SZE4 22101821 502 ATLICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIASRVQALIITRGEHGATIRHRDGTEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEIDARFETAFGYRP 3b1r F 2.0 BS01 AMP F 1 S8 D12 G48 C49 Q113 F117 P143 Q169 G250 D253 S7 D11 G47 C48 Q112 F116 P142 Q168 G249 D252 D247 P248 G250 C251 D246 P247 G249 C250 2.7.1.143 0000166,0016301,0016310,0016772 Q2SZE4 22101821 501 ATLICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIASRVQALIITRGEHGATIRHRDGTEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEIDARFETAFGYRP 3b1r F 2.0 BS02 AMP F 2 N111 T220 G222 E223 G225 S277 G280 I284 N110 T219 G221 E222 G224 S276 G279 I283 D247 P248 G250 C251 D246 P247 G249 C250 2.7.1.143 0000166,0016301,0016310,0016772 Q2SZE4 22101821 502 ATLICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIASRVQALIITRGEHGATIRHRDGTEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEIDARFETAFGYRP 3b6j B 2.05 BS03 AMP B 1 A145 Q146 E147 S180 Y184 E187 A144 Q145 E146 S179 Y183 E186 1.6.5.2 0000166,0003955,0005829,0006979,0008753,0010181,0016020,0016491,0032991,0042802,0050136,0050660,0050661,0051287 P0A8G6 17951395 202 AKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG 3ber A 1.4 BS01 AMP A 1 W44 K46 Q51 T70 G71 G73 T75 Q111 W34 K36 Q41 T60 G61 G63 T65 Q101 3.6.4.13 0003676,0003724,0005524 Q9H0S4 20941364 300 TEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSS 3blw A 4.3 BS02 AMP A 1 G277 N287 D328 G257 N267 D308 F136 K183 D217 T241 N245 F116 K163 D197 T221 N225 1.1.1.41 0000287,0003723,0004449,0005515,0005739,0005758,0005759,0005829,0006099,0006102,0006537,0016491,0016616,0042645,0045242,0046872,0051287 P28834 18256028 2001 GRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKEGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLSTM 3blw C 4.3 BS02 AMP C 1 G255 H275 V276 G277 G244 H264 V265 G266 F136 K183 D217 T241 N245 F125 K172 D206 T230 N234 1.1.1.41 0000287,0003723,0004449,0005515,0005739,0005758,0005759,0005829,0006099,0006102,0006537,0016491,0016616,0042645,0045242,0046872,0051287 P28834 18256028 2002 ERTLPKKYGGRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKEGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLSTM 3blw E 4.3 BS02 AMP E 1 H275 G277 H264 G266 F136 K183 D217 T241 N245 F125 K172 D206 T230 N234 1.1.1.41 0000287,0003723,0004449,0005515,0005739,0005758,0005759,0005829,0006099,0006102,0006537,0016491,0016616,0042645,0045242,0046872,0051287 P28834 18256028 2003 ERTLPKKYGGRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKEGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLSTM 3blw G 4.3 BS02 AMP G 1 H275 G277 N287 D328 H255 G257 N267 D308 F136 K183 D217 T241 N245 F116 K163 D197 T221 N225 1.1.1.41 0000287,0003723,0004449,0005515,0005739,0005758,0005759,0005829,0006099,0006102,0006537,0016491,0016616,0042645,0045242,0046872,0051287 P28834 18256028 2004 GRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKEGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLSTM 3blw I 4.3 BS02 AMP I 1 H275 G277 N287 D328 H255 G257 N267 D308 F136 K183 D217 T241 N245 F116 K163 D197 T221 N225 1.1.1.41 0000287,0003723,0004449,0005515,0005739,0005758,0005759,0005829,0006099,0006102,0006537,0016491,0016616,0042645,0045242,0046872,0051287 P28834 18256028 2005 GRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKEGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLSTM 3blw K 4.3 BS02 AMP K 1 V28 V276 G277 V21 V264 G265 F136 K183 D217 T241 N245 F124 K171 D205 T229 N233 1.1.1.41 0000287,0003723,0004449,0005515,0005739,0005758,0005759,0005829,0006099,0006102,0006537,0016491,0016616,0042645,0045242,0046872,0051287 P28834 18256028 2006 RTLPKKYGGRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKEGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLSTM 3blw M 4.3 BS02 AMP M 1 G255 H275 G277 N287 G245 H265 G267 N277 F136 K183 D217 T241 N245 F126 K173 D207 T231 N235 1.1.1.41 0000287,0003723,0004449,0005515,0005739,0005758,0005759,0005829,0006099,0006102,0006537,0016491,0016616,0042645,0045242,0046872,0051287 P28834 18256028 2007 AERTLPKKYGGRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKEGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLSTM 3blw O 4.3 BS02 AMP O 1 H275 V276 G277 N287 D328 H256 V257 G258 N268 D309 F136 K183 D217 T241 N245 F117 K164 D198 T222 N226 1.1.1.41 0000287,0003723,0004449,0005515,0005739,0005758,0005759,0005829,0006099,0006102,0006537,0016491,0016616,0042645,0045242,0046872,0051287 P28834 18256028 2008 GGRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKEGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLSTM 3c0h A 2.3 BS01 AMP A 1 I18 A39 M94 H145 L148 I14 A35 M90 H141 L144 D141 K143 H145 C146 G162 T182 D137 K139 H141 C142 G158 T178 2.7.11.1 0004672,0005524,0006468 O14936 18423203 338 DVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKL 3c0h B 2.3 BS01 AMP B 1 V26 A39 M94 H145 L148 V22 A35 M90 H141 L144 D141 K143 H145 C146 G162 T182 D137 K139 H141 C142 G158 T178 2.7.11.1 0004672,0005524,0006468 O14936 18423203 338 DVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKL 3c85 C 1.9 BS01 AMP C 1 G42 G44 E66 I67 R68 G85 A87 M109 P110 H111 G13 G15 E37 I38 R39 G56 A58 M80 P81 H82 ? 0006813 Q87RG9 201 LINPGHAQVLILGMGRIGTGAYDELRARYGKISLGIEIREEAAQQHRSEGRNVISGDATDPDFWERILDTGHVKLVLLAMPHHQGNQTALEQLQRRNYKGQIAAIAEYPDQLEGLLESGVDAAFNIYSEAGSGFARHVCKQLEPQF 3cj7 A 1.8 BS01 AMP A 1 S48 S49 H50 G204 R245 D246 Y350 R394 Y398 S13 S14 H15 G169 R210 D211 Y308 R352 Y356 3.6.1.- 0016787 O35795 18458329 501 PALKYGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVQGGGISSYANDPSKAGQSLVRCLEQALRDVPRDRHASTPLYLGATAGMRLLNLTSPEATARVLEAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPGNEVHLRLYGQHYRVYTHSFLCYGRDQILLRLLASALQIHRFHPCWPKGYSTQVLLQEVYQSPCTMGQSAIVSLSGTSNATLCRDLVSRLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLTTVMGLPVGTLKQLEEATEITCNQTWTELQARVPGQKTRLADYCAVAMFIHQLLSRGYHFDERSFREVVFQKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHF 3cj9 A 1.8 BS02 AMP A 1 H50 G203 R245 D246 Y350 R394 Y398 H15 G168 R210 D211 Y308 R352 Y356 3.6.1.- 0016787 O35795 18458329 501 PALKYGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVQGGGISSYANDPSKAGQSLVRCLEQALRDVPRDRHASTPLYLGATAGMRLLNLTSPEATARVLEAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPGNEVHLRLYGQHYRVYTHSFLCYGRDQILLRLLASALQIHRFHPCWPKGYSTQVLLQEVYQSPCTMGQRAIVSLSGTSNATLCRDLVSRLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLTTVMGLPVGTLKQLEEATEITCNQTWTELQARVPGQKTRLADYCAVAMFIHQLLSRGYHFDERSFREVVFQKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHF 3clr C 1.9 BS01 AMP C 1 A6 V7 K8 D39 S63 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 A6 V7 K8 D39 S63 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 ? 0000166,0009055 P53570 18407658 1262 MKILVAVKQTAALEEDFEIREDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASTKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPEKGRATMIEGTISEQAAKIIQIINEFK 3cls C 1.65 BS01 AMP C 1 A6 V7 K8 D39 S63 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 A6 V7 K8 D39 S63 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 ? 0000166,0009055 P53570 18407658 1262 MKILVAVKQTAALEEDFEIREDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASTKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPEKGRATMIEGTISEQAAKIIQIINEFK 3clt C 2.0 BS01 AMP C 1 A6 V7 K8 D39 S63 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 A6 V7 K8 D39 S63 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 ? 0000166,0009055 P53570 18407658 1262 MKILVAVKQTAALEEDFEIREDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASTKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPEKGRATMIEGTISEQAAKIIQIINEFKG 3clu C 1.8 BS01 AMP C 1 A6 V7 K8 N36 D39 S63 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 A6 V7 K8 N36 D39 S63 V64 V100 A118 G119 Q121 S122 Y127 A128 S129 T130 ? 0000166,0009055 P53570 18407658 1262 MKILVAVKQTAALEEDFEIREDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVVVVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGSDAIVVGRILTEVIKKEAPDMVFAGVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPAVLTIQLGINKPRYASKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPEKGRATMIEGTISEQAAKIIQIINEF 3cw9 A 2.0 BS01 AMP A 1 T161 G281 A282 T283 I303 Y304 G305 T306 T307 D385 R400 I406 N411 T161 G281 A282 T283 I303 Y304 G305 T306 T307 D385 R400 I406 N411 T161 R181 H207 T307 E308 I406 N411 K492 T161 R181 H207 T307 E308 I406 N411 K492 6.2.1.33 0000166,0003824,0006631,0016020,0016874,0031956,0046872 Q8GN86 18620418 997 MQTVNEMLRRAATRAPDHCALAVPARGLRLTHAELRARVEAVAARLHADGLRPQQRVAVVAPNSADVVIAILALHRLGAVPALLNPRLKSAELAELIKRGEMTAAVIAVGRQVADAIFQSGSGARIIFLGDLVRDGEPYSYGPPIEDPQREPAQPAFIFYTSGTTGLPKAAIIPQRAAESRVLFMSTQVGLRHGRHNVVLGLMPLYHVVGFFAVLVAALALDGTYVVVEEFRPVDALQLVQQEQVTSLFATPTHLDALAAAAAHAGSSLKLDSLRHVTFAGATMPDAVLETVHQHLPGEKVNIYGTTEAMNSLYMRQPKTGTEMAPGFFSEVRIVRIGGGVDEIVANGEEGELIVAASDSAFVGYLNQPQATAEKLQDGWYRTSDVAVWTPEGTVRILGRVDDMIISGGENIHPSEIERVLGTAPGVTEVVVIGLADQRWGQSVTACVVPRLGETLSADALDTFCRSSELADFKRPKRYFILDQLPKNALNKVLRRQLVQQVS 3cw9 B 2.0 BS01 AMP B 1 T161 G281 A282 T283 I303 Y304 G305 T306 T307 D385 R400 I406 N411 T161 G281 A282 T283 I303 Y304 G305 T306 T307 D385 R400 I406 N411 T161 R181 H207 T307 E308 I406 N411 K492 T161 R181 H207 T307 E308 I406 N411 K492 6.2.1.33 0000166,0003824,0006631,0016020,0016874,0031956,0046872 Q8GN86 18620418 999 MQTVNEMLRRAATRAPDHCALAVPARGLRLTHAELRARVEAVAARLHADGLRPQQRVAVVAPNSADVVIAILALHRLGAVPALLNPRLKSAELAELIKRGEMTAAVIAVGRQVADAIFQSGSGARIIFLGDLVRDGEPYSYGPPIEDPQREPAQPAFIFYTSGTTGLPKAAIIPQRAAESRVLFMSTQVGLRHGRHNVVLGLMPLYHVVGFFAVLVAALALDGTYVVVEEFRPVDALQLVQQEQVTSLFATPTHLDALAAAAAHAGSSLKLDSLRHVTFAGATMPDAVLETVHQHLPGEKVNIYGTTEAMNSLYMRQPKTGTEMAPGFFSEVRIVRIGGGVDEIVANGEEGELIVAASDSAFVGYLNQPQATAEKLQDGWYRTSDVAVWTPEGTVRILGRVDDMIISGGENIHPSEIERVLGTAPGVTEVVVIGLADQRWGQSVTACVVPRLGETLSADALDTFCRSSELADFKRPKRYFILDQLPKNALNKVLRRQLVQQVS 3dah A 2.3 BS01 AMP A 1 R99 Q100 H134 R95 Q96 H130 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009156,0009165,0016301,0016310,0044249,0046872 Q63XL8 23382856 401 DGLMVFTGNANPALAQEVVKILGIPLGKAMVSRFSDGEIQVEIQENVRGKDVFVLQSTCAPTNDNLMELMIMVDALKRASAGRITAAIPYFGYARQDRRPRSARVAISAKVVANMLEIAGVERIITMDLHADQIQGFFDIPVDNIYATPILLGDLRKQNYPDLLVVSPDVGGVVRARALAKQLNCDLAIEGRTCVIMDDMVDTAGTLCKAAQVLKERGAKQVFAYATHPVLSGGAADRIAASALDELVVTDTIPLSAESLACPKIRALSSAGLLAETFSRIRRGDSVMSL 3dah B 2.3 BS01 AMP B 1 F38 D40 E42 F34 D36 E38 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009156,0009165,0016301,0016310,0044249,0046872 Q63XL8 23382856 401 DGLMVFTGNANPALAQEVVKILGIPLGKAMVSRFSDGEIQVEIQENVRGKDVFVLQSTCAPTNDNLMELMIMVDALKRASAGRITAAIPYFGYARQDRRPRSARVAISAKVVANMLEIAGVERIITMDLHADQIQGFFDIPVDNIYATPILLGDLRKQNYPDLLVVSPDVGGVVRARALAKQLNCDLAIGEVEGRTCVIMDDMVDTAGTLCKAAQVLKERGAKQVFAYATHPVLSGGAADRIAASALDELVVTDTIPLSAESLACPKIRALSSAGLLAETFSRIRRGDSVMSLF 3dah B 2.3 BS02 AMP B 2 R99 Q100 R102 R95 Q96 R98 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009156,0009165,0016301,0016310,0044249,0046872 Q63XL8 23382856 402 DGLMVFTGNANPALAQEVVKILGIPLGKAMVSRFSDGEIQVEIQENVRGKDVFVLQSTCAPTNDNLMELMIMVDALKRASAGRITAAIPYFGYARQDRRPRSARVAISAKVVANMLEIAGVERIITMDLHADQIQGFFDIPVDNIYATPILLGDLRKQNYPDLLVVSPDVGGVVRARALAKQLNCDLAIGEVEGRTCVIMDDMVDTAGTLCKAAQVLKERGAKQVFAYATHPVLSGGAADRIAASALDELVVTDTIPLSAESLACPKIRALSSAGLLAETFSRIRRGDSVMSLF 3dah C 2.3 BS01 AMP B 1 R99 Q100 R94 Q95 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009156,0009165,0016301,0016310,0044249,0046872 Q63XL8 23382856 401 GLMVFTGNANPALAQEVVKILGIPLGKAMVSRFSDGEIQVEIQENVRGKDVFVLQSTCAPTNDNLMELMIMVDALKRASAGRITAAIPYFGYARQDRRPRSARVAISAKVVANMLEIAGVERIITMDLHADQIQGFFDIPVDNIYATPILLGDLRKQNYPDLLVVSPDVGGVVRARALAKQLNCDLAIIDKRRVMNIIGEVEGRTCVIMDDMVDTAGTLCKAAQVLKERGAKQVFAYATHPVLSGGAADRIAASALDELVVTDTIPLSAESLACPKIRALSSAGLLAETFSRIRRGDSVM 3dah C 2.3 BS02 AMP B 2 F38 D40 E42 F33 D35 E37 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009156,0009165,0016301,0016310,0044249,0046872 Q63XL8 23382856 402 GLMVFTGNANPALAQEVVKILGIPLGKAMVSRFSDGEIQVEIQENVRGKDVFVLQSTCAPTNDNLMELMIMVDALKRASAGRITAAIPYFGYARQDRRPRSARVAISAKVVANMLEIAGVERIITMDLHADQIQGFFDIPVDNIYATPILLGDLRKQNYPDLLVVSPDVGGVVRARALAKQLNCDLAIIDKRRVMNIIGEVEGRTCVIMDDMVDTAGTLCKAAQVLKERGAKQVFAYATHPVLSGGAADRIAASALDELVVTDTIPLSAESLACPKIRALSSAGLLAETFSRIRRGDSVM 3ddj A 1.8 BS01 AMP A 1 S144 V147 Q148 F168 R169 R170 T256 D259 S147 V150 Q151 F171 R172 R173 T259 D262 ? 0000166 Q97U20 278 NLYFQGMNIETLMIKNPPILSKEDRLGSAFKKINEGGIGRIIVANEKIEGLLTTRDLLSTVESYCCSQGDLYHISTTPIIDYMTPNPVTVYNTSDEFTAINIMVTRNFGSLPVVDINDKPVGIVTEREFLLLYKDLDEIFPVKVFMSTKVQTIYKEVRLDQAVKLMLRRGFRRLPVIDDDNKVVGIVTVVNAIKQLAKAVDKLDPDYFYGKVVKDVMVTNLVTIDELASVNRAAAEMIVKRIGSLLILNKDNTIRGIITERDLLIALHHILVMEKFKEK 3dhv A 2.0 BS02 AMP A 1 G270 E271 V272 T293 Y294 T297 V321 D383 Y394 R397 G264 E265 V266 T287 Y288 T291 V315 D377 Y388 R391 T152 F172 T297 E298 K403 R408 K492 T151 F166 T291 E292 K397 R402 K486 6.2.1.54 0005524,0005737,0016874,0047473,0070395 Q81G39 18847223 711 KLLEQIEKWAAETPDQTAFVWRDAKITYKQLKEDSDALAHWISSEYPDDRSPIMVYGHMQPEMIINFLGCVKAGHAYIPVDLSIPADRVQRIAENSGAKLLLSATAVTVTDLPVRIVSEDNLKDIFFTHKGNTPNPEHAVKGDENFYIIYTSPKGVQITYNCLVSFTKWAVEDFNLQTGQVFLNQAPFSFDLSVMDIYPSLVTGGTLWAIDKDMIARPKDLFASLEQSDIQVWTSTPSFAEMCLMEASFSESMLPNMKTFLFCGEVLPNEVARKLIERFPKATIMNTYGPTEATVAVTGIHVTEEVLDQYKSLPVGYCKSDCRLLIMKEDGTIAPDGEKGEIVIVGPSVSVGYLGSPELTEKAFTMIDGERAYKTGDAGYVENGLLFYNGRLDFQIKLHGYRMELEEIEHHLRACSYVEGAVIVPIKKGEKYDYLLAVVVPGEHSFEKEFKLTSAIKKELNERLPNYMIPRKFMYQSSIPMTPNGKVDRKKLLSEVTA 3dlz A 1.85 BS02 AMP A 1 I490 G491 F495 V498 A509 K511 F607 G608 D611 G653 N654 L656 I686 D687 I21 G22 F26 V29 A40 K42 F138 G139 D142 G184 N185 L187 I217 D218 2.7.11.1 0004672,0005524,0006468 Q8TF76 19918057 902 KGPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK 3dqx A 2.3 BS01 AMP A 1 V281 A293 M341 L393 D404 V23 A35 M83 L135 D146 D386 R388 A390 N391 D404 F424 D128 R130 A132 N133 D146 F158 2.7.10.2 0004672,0004713,0005524,0006468 P00523 18794843 1 AWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 3dqx B 2.3 BS01 AMP B 1 V281 A293 K295 M341 L393 D404 V23 A35 K37 M83 L135 D146 D386 R388 A390 N391 D404 F424 D128 R130 A132 N133 D146 F159 2.7.10.2 0004672,0004713,0005524,0006468 P00523 18794843 2 AWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 3drw A 1.9 BS01 AMP A 1 T336 L421 V422 L431 I435 T346 L431 V432 L441 I445 2.7.1.146 0000287,0005737,0005975,0006000,0006096,0008443,0016301,0016310,0016773,0043844,0046835,0046872 O59355 19553681 1484 SGRENLYFQGMIPEHLSIYTAYNANIAAIVKLNQETIQNLINAFDPDEVKRRIEEYPREINEPIDFVARLVHTLKLGKPAAVPLVNEKMNEWFDKTFRYEEERLGGQAGIIANTLAGLKIRKVIAYTPFLPKRLAELFKKGVLYPVVENGELQFKPIQEAYREGDPLKINRIFEFRKGLKFKLGDETIEIPNSGRFIVSARFESISRIETREDIKPFLGEIGKEVDGAIFSGYQGLRTKYSDGKDANYYLRRAKEDIIEFKEKDVKIHVEFASVQDRKLRKKIITNILPFVDSVGIDEAEIAQILSVLGYRELADRIFTYNRLEDSILGGMIILDELNFEILQVHTTYYLMYITHRDNPLSEEELAKSLEFGTTLAAARASLGDIRGPDDYKVGLKVPFNERSEYVKLRFEEAKSRLRMREYKVVVIPTRLVQNPVLTVGLGDTISAGAFLTYLEFLKRH 3drw B 1.9 BS01 AMP B 1 T336 L421 V422 L431 G432 I435 T336 L421 V422 L431 G432 I435 2.7.1.146 0000287,0005737,0005975,0006000,0006096,0008443,0016301,0016310,0016773,0043844,0046835,0046872 O59355 19553681 1485 MIPEHLSIYTAYNANIAAIVKLNQETIQNLINAFDPDEVKRRIEEYPREINEPIDFVARLVHTLKLGKPAAVPLVNEKMNEWFDKTFRYEEERLGGQAGIIANTLAGLKIRKVIAYTPFLPKRLAELFKKGVLYPVVENGELQFKPIQEAYREGDPLKINRIFEFRKGLKFKLGDETIEIPNSGRFIVSARFESISRIETREDIKPFLGEIGKEVDGAIFSGYQGLRTKYSDGKDANYYLRRAKEDIIEFKEKDVKIHVEFASVQDRKLRKKIITNILPFVDSVGIDEAEIAQILSVLGYRELADRIFTYNRLEDSILGGMIILDELNFEILQVHTTYYLMYITHRDNPLSEEELAKSLEFGTTLAAARASLGDIRGPDDYKVGLKVPFNERSEYVKLRFEEAKSRLRMREYKVVVIPTRLVQNPVLTVGLGDTISAGAFLTYLEFLKRH 3e3n A 2.7 BS01 AMP A 1 W67 Q71 Y75 R309 R310 F316 G317 W61 Q65 Y69 R286 R287 F293 G294 H377 K568 R569 K574 T676 K680 H354 K545 R546 K551 T653 K657 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 QEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 3e3n A 2.7 BS02 AMP B 1 D42 N44 V45 D36 N38 V39 H377 K568 R569 K574 T676 K680 H354 K545 R546 K551 T653 K657 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 QEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 3e3n B 2.7 BS01 AMP A 1 D42 N44 V45 D36 N38 V39 H377 K568 R569 K574 T676 K680 H355 K546 R547 K552 T654 K658 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 QEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYPGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 3e3n B 2.7 BS02 AMP B 1 W67 Q71 Y75 R309 R310 F316 G317 C318 W61 Q65 Y69 R287 R288 F294 G295 C296 H377 K568 R569 K574 T676 K680 H355 K546 R547 K552 T654 K658 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 QEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYPGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 3e3n C 2.7 BS01 AMP C 1 W67 Q71 Y75 R309 R310 W59 Q63 Y67 R284 R285 H377 K568 R569 K574 T676 K680 H342 K533 R534 K539 T641 K645 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 KRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 3e3n C 2.7 BS02 AMP D 1 D42 N44 V45 D34 N36 V37 H377 K568 R569 K574 T676 K680 H342 K533 R534 K539 T641 K645 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 KRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 3e3n D 2.7 BS01 AMP C 1 D42 N44 V45 D36 N38 V39 H377 K568 R569 K574 T676 K680 H354 K545 R546 K551 T653 K657 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 QEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPD 3e3n D 2.7 BS02 AMP D 1 W67 Q71 Y75 R309 R310 F316 G317 C318 W61 Q65 Y69 R286 R287 F293 G294 C295 H377 K568 R569 K574 T676 K680 H354 K545 R546 K551 T653 K657 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 QEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPD 3e3n E 2.7 BS01 AMP E 1 W67 Q71 Y75 R309 R310 W60 Q64 Y68 R285 R286 H377 K568 R569 K574 T676 K680 H343 K534 R535 K540 T642 K646 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 EKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 3e3n E 2.7 BS02 AMP F 1 D42 N44 V45 D35 N37 V38 H377 K568 R569 K574 T676 K680 H343 K534 R535 K540 T642 K646 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 EKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 3e3n F 2.7 BS01 AMP E 1 D42 N44 V45 D35 N37 V38 H377 K568 R569 K574 T676 K680 H353 K544 R545 K550 T652 K656 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 EKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 3e3n F 2.7 BS02 AMP F 1 Q71 Y75 R309 R310 F316 G317 Q64 Y68 R285 R286 F292 G293 H377 K568 R569 K574 T676 K680 H353 K544 R545 K550 T652 K656 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 EKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 3e3n G 2.7 BS01 AMP G 1 W67 Q71 Y75 R309 R310 F316 G317 W61 Q65 Y69 R286 R287 F293 G294 H377 K568 R569 K574 T676 K680 H354 K545 R546 K551 T653 K657 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 QEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 3e3n G 2.7 BS02 AMP H 1 D42 N44 V45 D36 N38 V39 H377 K568 R569 K574 T676 K680 H354 K545 R546 K551 T653 K657 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 QEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 3e3n H 2.7 BS01 AMP G 1 D42 N44 D37 N39 H377 K568 R569 K574 T676 K680 H355 K546 R547 K552 T654 K658 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 DQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 3e3n H 2.7 BS02 AMP H 1 W67 Q71 Y75 R309 R310 F316 G317 C318 W62 Q66 Y70 R287 R288 F294 G295 C296 H377 K568 R569 K574 T676 K680 H355 K546 R547 K552 T654 K658 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 34473107 843 DQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNGYIQAVLDRNLAENISRVLYGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 3e7w A 2.28 BS01 AMP A 1 G269 E270 V271 T292 Y293 G294 T296 V320 D382 K402 R407 G269 E270 V271 T292 Y293 G294 T296 V320 D382 K402 R407 T151 F171 T296 E297 K402 R407 K491 T151 F171 T296 E297 K402 R407 K491 6.2.1.54 0005524,0005737,0016874,0047473,0070395 P39581 18784082 513 MKLLHAIQTHAETYPQTDAFRSQGQSLTYQELWEQSDRAAAAIQKRISGEKKSPILVYGHMEPHMIVSFLGSVKAGHPYIPVDLSIPSERIAKIIESSGAELLIHAAGLSIDAVGQQIQTVSAEELLENEGGSVSQDQWVKEHETFYIIYTSGSTGNPKGVQISAANLQSFTDWICADFPVSGGKIFLNQAPFSFDLSVMDLYPCLQSGGTLHCVTKDAVNKPKVLFEELKKSGLNVWTSTPSFVQMCLMDPGFSQDLLPHADTFMFCGEVLPVSVAKALLERFPKAKIFNTYGPTEATVAVTSVEITNDVISRSESLPVGFAKPDMNIFIMDEEGQPLPEGEKGEIVIAGPSVSRGYLGEPELTEKAFFSHEGQWAYRTGDAGFIQDGQIFCQGRLDFQIKLHGYRMELEEIEFHVRQSQYVRSAVVIPYQPNGTVEYLIAAIVPEEHEFEKEFQLTSAIKKELAASLPAYMIPRKFIYQDHIQMTANGKIDRKRIGEEVLVRSHHH 3e7x A 2.6 BS01 AMP A 1 G269 E270 V271 T292 Y293 P295 T296 D382 K402 R407 G269 E270 V271 T292 Y293 P295 T296 D382 K402 R407 T151 F171 T296 E297 K402 R407 K491 T151 F171 T296 E297 K402 R407 K491 6.2.1.54 0005524,0005737,0016874,0047473,0070395 P39581 18784082 512 MKLLHAIQTHAETYPQTDAFRSQGQSLTYQELWEQSDRAAAAIQKRISGEKKSPILVYGHMEPHMIVSFLGSVKAGHPYIPVDLSIPSERIAKIIESSGAELLIHAAGLSIDAVGQQIQTVSAEELLENEGGSVSQDQWVKEHETFYIIYTSGSTGNPKGVQISAANLQSFTDWICADFPVSGGKIFLNQAPFSFDLSVMDLYPCLQSGGTLHCVTKDAVNKPKVLFEELKKSGLNVWTSTPSFVQMCLMDPGFSQDLLPHADTFMFCGEVLPVSVAKALLERFPKAKIFNTYGPTEATVAVTSVEITNDVISRSESLPVGFAKPDMNIFIMDEEGQPLPEGEKGEIVIAGPSVSRGYLGEPELTEKAFFSHEGQWAYRTGDAGFIQDGQIFCQGRLDFQIKLHGYRMELEEIEFHVRQSQYVRSAVVIPYQPNGTVEYLIAAIVPEEHEFEKEFQLTSAIKKELAASLPAYMIPRKFIYQDHIQMTANGKIDRKRIGEEVLVRSHHH 3eps A 2.8 BS01 AMP A 1 N104 S105 H113 K291 K294 T295 Y298 F375 E376 N377 N103 S104 H112 K290 K293 T294 Y297 F374 E375 N376 2.7.11.5,3.1.3.- 0004674,0004721,0005524,0005737,0006006,0006097,0006099,0006470,0008772,0016208,0016310,0016788,0016791,0018105,0050790 Q8X607 20505668 1604 PRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYG 3eps B 2.8 BS01 AMP B 1 N104 S105 H113 L116 K291 K294 T295 Y298 E376 N377 N103 S104 H112 L115 K290 K293 T294 Y297 E375 N376 2.7.11.5,3.1.3.- 0004674,0004721,0005524,0005737,0006006,0006097,0006099,0006470,0008772,0016208,0016310,0016788,0016791,0018105,0050790 Q8X607 20505668 1604 PRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYG 3eq6 A 2.4 BS01 AMP A 1 G338 E339 S340 E359 S360 Y361 G362 Q363 T364 D446 F458 R461 R472 G302 E303 S304 E323 S324 Y325 G326 Q327 T328 D410 F422 R425 R436 T221 T364 E365 N467 R472 K557 T185 T328 E329 N431 R436 K521 6.2.1.2,6.2.1.25 0004321,0005524,0005739,0005759,0006631,0006633,0006637,0015645,0016874,0018858,0031956,0036112,0042593,0046872,0070328,0102391 Q08AH3 19345228 901 HQEVPAKFNFASDVLDHWADMEKAGKRPPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKEWK 3eq6 B 2.4 BS01 AMP B 1 G338 E339 S340 Y361 G362 Q363 T364 D446 F458 R461 R472 G302 E303 S304 Y325 G326 Q327 T328 D410 F422 R425 R436 T221 T364 E365 N467 R472 K557 T185 T328 E329 N431 R436 K521 6.2.1.2,6.2.1.25 0004321,0005524,0005739,0005759,0006631,0006633,0006637,0015645,0016874,0018858,0031956,0036112,0042593,0046872,0070328,0102391 Q08AH3 19345228 902 HQEVPAKFNFASDVLDHWADMEKAGKRPPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKEWK 3err A 2.27 BS01 AMP A 1 R256 E258 M270 V272 F275 E345 T346 S348 T380 R363 E365 M377 V379 F382 E452 T453 S455 T487 R256 R271 E345 S348 R386 R363 R378 E452 S455 R493 ?,6.1.1.11 0000166,0004812,0004828,0005524,0006418,0006434 Q5SJX7,Q9JHU4 19074350 1507 DLKRLRQEPEVFHRAIREKGVALDLEALLAVDEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESIALLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLAAGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKLEALLLQVPLPPWPGAPVGGEEANREIKRVGGPPEFSFPPLDHVALMEKNGWWEPRISQVSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVWAIAETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSFGKDVRGLMRVHQFHKVEQYVLTEASLEASDRAFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTLNNTALATPRILAMLLENHQLQDGRVRVPQALIPYMGKEVLEPG 3err B 2.27 BS01 AMP B 1 R256 M270 R271 V272 F275 K277 E345 T346 R386 R363 M377 R378 V379 F382 K384 E452 T453 R493 R256 R271 E345 S348 R386 R363 R378 E452 S455 R493 ?,6.1.1.11 0000166,0004812,0004828,0005524,0006418,0006434 Q5SJX7,Q9JHU4 19074350 1508 DLKRLRQEPEVFHRAIREKGVALDLEALLAVDEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESIALLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLAAGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKLEALLLQVPLPPWPGAPVGGEEANREIKRVGGPPEFSFPPLDHVALMEKNGWWEPRISQVSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVWAIAETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSFGKDVRGLMRVHQFHKVEQYVLTEASLEASDRAFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTLNNTALATPRILAMLLENHQLQDGRVRVPQALIPYMGKEVLEPG 3feg A 1.302 BS03 AMP A 1 L82 L102 Y147 I148 L249 L36 L56 Y98 I99 L200 2.7.1.32,2.7.1.82 0004103,0004305,0005524,0005737,0005829,0006646,0006656,0006657,0007517,0008654,0016301,0016310 Q9Y259 20299452 398 SRDAERRAYQWCREYLGGAWRRVQPEELRVYPVNLLFRCSLPDHLPSVGEEPREVLLRLYGQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPVLSAAIATKMAQFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPTGLPEMNLLEMYSLKDEMGNLRKLLESTPSPVVFCHNDIQEGNILLLSEPDSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQASMSTIEFGYLDYAQSRFQFYFQQKGQL 3fhj A 2.65 BS02 AMP A 1 G17 N18 G21 I183 K192 G12 N13 G16 I165 K174 K192 K195 K174 K177 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYPGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fhj B 2.65 BS03 AMP B 1 G17 N18 G21 G12 N13 G16 K192 K195 K166 K169 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYFTIPERIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYPGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fhj C 2.65 BS02 AMP C 1 G17 N18 K192 M193 G12 N13 K174 M175 K192 K195 K174 K177 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTPGISNLLNIYSTLGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fhj D 2.65 BS03 AMP D 1 G17 N18 I183 K192 M193 G17 N18 I166 K175 M176 K192 K195 K175 K178 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQPSGVITIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSAISNLLNIYSTLSGQSIEELERQYVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fhj E 2.65 BS03 AMP E 1 G17 N18 G21 I183 K192 M193 G12 N13 G16 I165 K174 M175 K192 K195 K174 K177 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSPGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fhj F 2.65 BS03 AMP F 1 G17 N18 I183 K192 M193 G17 N18 I162 K171 M172 K192 K195 K171 K174 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQPSGVITIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYFTIPEARRIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYPGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fhm A 2.7 BS01 AMP A 1 I52 T54 R56 D57 T79 V83 F103 R104 H105 I58 T60 R62 D63 T85 V89 F109 R110 H111 ? 0000166 A9CIP4 200 NLYFQGMATFVKDLLDRKGRDVVTVGPDVSIGEAAGTLHAHKIGAVVVTDADGVVLGIFTERDLVKAVAGQGAASLQQSVSVAMTKNVVRCQHNSTTDQLMEIMTGGRFRHVPVEENGRLAGIISIGDVVKARIGE 3fhm B 2.7 BS01 AMP B 1 I52 T54 D57 T79 V83 F103 R104 H105 I50 T52 D55 T77 V81 F101 R102 H103 ? 0000166 A9CIP4 200 TFVKDLLDRKGRDVVTVGPDVSIGEAAGTLHAHKIGAVVVTDADGVVLGIFTERDLVKAVAGQGAASLQQSVSVAMTKNVVRCQHNSTTDQLMEIMTGGRFRHVPVEENGRLAGIISIGDVVKARI 3fhm C 2.7 BS02 AMP C 1 I52 T54 D57 T79 V83 F103 R104 H105 I58 T60 D63 T85 V89 F109 R110 H111 ? 0000166 A9CIP4 200 NLYFQGMATFVKDLLDRKGRDVVTVGPDVSIGEAAGTLHAHKIGAVVVTDADGVVLGIFTERDLVKAVAGQGAASLQQSVSVAMTKNVVRCQHNSTTDQLMEIMTGGRFRHVPVEENGRLAGIISIGDVVKARI 3fhm D 2.7 BS02 AMP D 1 I52 T54 D57 T79 V83 F103 R104 H105 I51 T53 D56 T78 V82 F102 R103 H104 ? 0000166 A9CIP4 200 ATFVKDLLDRKGRDVVTVGPDVSIGEAAGTLHAHKIGAVVVTDADGVVLGIFTERDLVKAVAGQGAASLQQSVSVAMTKNVVRCQHNSTTDQLMEIMTGGRFRHVPVEGRLAGIISIGDVVKARI 3fi0 A 2.7 BS02 AMP A 1 G17 N18 I183 K192 M193 G12 N13 I164 K173 M174 K192 K195 K173 K176 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPRIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 B 2.7 BS02 AMP B 1 G17 N18 R182 I183 K192 M193 G12 N13 R161 I162 K171 M172 K192 K195 K171 K174 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYLFTIPEARIPRIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 C 2.7 BS02 AMP C 1 G17 N18 I183 K192 M193 G12 N13 I164 K173 M174 K192 K195 K173 K176 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPRIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 D 2.7 BS02 AMP D 1 G17 N18 A22 I183 K192 M193 G12 N13 A17 I168 K177 M178 K192 K195 K177 K180 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 E 2.7 BS02 AMP E 1 G17 G21 I183 K192 M193 G10 G14 I166 K175 M176 K192 K195 K175 K178 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYDGISNLLNIYSTLSGQSIEELERGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 F 2.7 BS02 AMP F 1 G17 N18 I183 G11 N12 I163 K192 K195 K172 K175 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 G 2.7 BS02 AMP G 1 G17 N18 I183 K192 M193 G13 N14 I169 K178 M179 K192 K195 K178 K181 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQITIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 H 2.7 BS02 AMP H 1 G17 N18 G144 K192 G12 N13 G129 K177 K192 K195 K177 K180 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 I 2.7 BS02 AMP I 1 G17 N18 I183 K192 M193 G12 N13 I168 K177 M178 K192 K195 K177 K180 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 J 2.7 BS02 AMP J 1 G17 N18 I183 M193 G12 N13 I168 M178 K192 K195 K177 K180 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 K 2.7 BS02 AMP K 1 G17 N18 G21 A22 I176 R182 I183 K192 M193 G12 N13 G16 A17 I160 R166 I167 K176 M177 K192 K195 K176 K179 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 L 2.7 BS02 AMP L 1 G17 N18 I183 K192 M193 G12 N13 I168 K177 M178 K192 K195 K177 K180 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 M 2.7 BS02 AMP M 1 G17 D146 Q147 G12 D131 Q132 K192 K195 K177 K180 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 N 2.7 BS02 AMP N 1 G17 N18 I176 I183 M193 G12 N13 I161 I168 M178 K192 K195 K177 K180 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 O 2.7 BS02 AMP O 1 G17 N18 R182 I183 K192 M193 G12 N13 R167 I168 K177 M178 K192 K195 K177 K180 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 P 2.7 BS02 AMP P 1 G17 G144 K192 M193 G12 G128 K176 M177 K192 K195 K176 K179 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 Q 2.7 BS02 AMP Q 1 G17 N18 R182 I183 K192 M193 G12 N13 R167 I168 K177 M178 K192 K195 K177 K180 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIRYGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fi0 R 2.7 BS02 AMP R 1 G17 N18 G21 I183 G12 N13 G16 I164 K192 K195 K173 K176 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0006412,0006418,0006436 P00953 19174517 1003 MKTIFSGIQTIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPRIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSSEGTIGISNLLNIYSTLSGQSIEELERQYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGR 3fiu A 1.85 BS02 AMP A 1 G35 L36 S37 L61 R124 T142 D158 S193 G30 L31 S32 L56 R113 T131 D147 S182 0003952,0004359,0005737,0008795,0009435 19204287 3001 DFSPKEYSQKLVNWLSDSCMNYPAEGFVIGLSGGIDSAVAASLAVKTGLPTTALILPSDNNQHQDMQDALELIEMLNIEHYTISIQPAYEAFLASTQSFTQLVIKGNAQARLRMMYLYAYAQQYNRIVIGTDNACEWYMGYFTKFGDGAADILPLVNLKKSQVFELGKYLDVPKNILDKAPSAGLWQGQTDEDEMGVTYQEIDDFLDGKQVSAKALERINFWHNRSHHKRKLALTPNF 3fiu B 1.85 BS02 AMP B 1 G35 L36 S37 L61 R124 T142 D158 S193 G30 L31 S32 L56 R113 T131 D147 S182 0003952,0004359,0005737,0008795,0009435 19204287 3001 DFSPKEYSQKLVNWLSDSCMNYPAEGFVIGLSGGIDSAVAASLAVKTGLPTTALILPSDNNQHQDMQDALELIEMLNIEHYTISIQPAYEAFLASTQSFTQLVIKGNAQARLRMMYLYAYAQQYNRIVIGTDNACEWYMGYFTKFGDGAADILPLVNLKKSQVFELGKYLDVPKNILDKAPSAGLWQGQTDEDEMGVTYQEIDDFLDGKQVSAKALERINFWHNRSHHKRKLALTPNF 3fiu C 1.85 BS02 AMP C 1 G35 L36 S37 L61 R124 T142 D158 S193 G30 L31 S32 L56 R113 T131 D147 S182 0003952,0004359,0005737,0008795,0009435 19204287 3001 DFSPKEYSQKLVNWLSDSCMNYPAEGFVIGLSGGIDSAVAASLAVKTGLPTTALILPSDNNQHQDMQDALELIEMLNIEHYTISIQPAYEAFLASTQSFTQLVIKGNAQARLRMMYLYAYAQQYNRIVIGTDNACEWYMGYFTKFGDGAADILPLVNLKKSQVFELGKYLDVPKNILDKAPSAGLWQGQTDEDEMGVTYQEIDDFLDGKQVSAKALERINFWHNRSHHKRKLALTPNF 3fiu D 1.85 BS02 AMP D 1 G35 L36 S37 S42 L61 R124 T142 D158 S193 G30 L31 S32 S37 L56 R113 T131 D147 S182 0003952,0004359,0005737,0008795,0009435 19204287 3001 DFSPKEYSQKLVNWLSDSCMNYPAEGFVIGLSGGIDSAVAASLAVKTGLPTTALILPSDNNQHQDMQDALELIEMLNIEHYTISIQPAYEAFLASTQSFTQLVIKGNAQARLRMMYLYAYAQQYNRIVIGTDNACEWYMGYFTKFGDGAADILPLVNLKKSQVFELGKYLDVPKNILDKAPSAGLWQGQTDEDEMGVTYQEIDDFLDGKQVSAKALERINFWHNRSHHKRKLALTPNF 3fna A 2.1 BS01 AMP A 1 T261 D264 R267 T285 I309 T57 D60 R63 T75 I99 401 LGRKLLLRVNDIMHTGDEIPHVKKTASLRDALLEVTRKNLGMTVICDDNMMIEGIFTDGDLRRVFDRLSIADVMTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMHDLL 3fna B 2.1 BS01 AMP B 1 I259 T261 D264 R267 T285 G288 I289 I309 S311 I54 T56 D59 R62 T77 G80 I81 I101 S103 401 GRKLLLRVNDIMHTGDEIPHVKKTASLRDALLEVTRKNLGMTVICDDNMMIEGIFTDGDLRRVFDMVRRLSIADVMTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMHDLLR 3fwz A 1.79 BS01 AMP A 1 G426 R427 V428 E447 T448 R452 N467 I489 R514 G16 R17 V18 E37 T38 R42 N57 I79 R104 ? 0006813 P39830 601 SNAVDICNHALLVGYGRVGSLLGEKLLASDIPLVVIETSRTRVDELRERGVRAVLGNAANEEIMQLAHLECAKWLILTIPNGYEAGEIVASARAKNPDIEIIARAHYDDEVAYITERGANQVVMGEREIARTMLELLETP 3fwz B 1.79 BS01 AMP B 1 G426 R427 E447 T448 N467 I489 R514 G13 R14 E34 T35 N54 I76 R101 ? 0006813 P39830 601 VDICNHALLVGYGRVGSLLGEKLLASDIPLVVIETSRTRVDELRERGVRAVLGNAANEEIMQLAHLECAKWLILTIPNGYEAGEIVASARAKNPDIEIIARAHYDDEVAYITERGANQVVMGEREIARTMLELLE 3g1z A 1.95 BS01 AMP A 1 R100 H108 N109 F112 M114 E244 L245 A246 A298 G300 R303 R93 H101 N102 F105 M107 E237 L238 A239 A290 G292 R295 6.3.1.- 0000049,0000166,0004812,0004824,0005524,0005737,0005829,0006418,0006430,0016874,0016880,0071915 Q9ZJ12 20670890 401 ATWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLFPFETRFVGSQGINLYLMTSPEYHMKRLLAAGCGPVFQLCRSFRNEEMGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCQPAESLSYQQAFQRHLEIDPLSADKTQLREAAAKLDLSNIADTEEDRDTLLQLLFTMGVEPHIGKEKPTFIYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARLPQQPIDQNLLDALAAGLPDCSGVALGVDRLVMLALGAESLADVIAFTVDRA 3g1z B 1.95 BS01 AMP B 1 R100 H108 N109 F112 E244 N247 G300 R303 R93 H101 N102 F105 E231 N234 G284 R287 6.3.1.- 0000049,0000166,0004812,0004824,0005524,0005737,0005829,0006418,0006430,0016874,0016880,0071915 Q9ZJ12 20670890 401 ATWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLFPFETRFVGPQGINLYLMTSPEYHMKRLLAAGCGPVFQLCRSFRNEEMGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCQPAESLSYQQAFQRHLEIDPLSADKTQLREAAAKLDLEEDRDTLLQLLFTMGVEPHIGKEKPTFIYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRGLPQQPIDQNLLDALAAGLPDCSGVALGVDRLVMLALGAESLADVIAFTVDRA 3g89 A 1.5 BS02 AMP A 1 R245 H246 R235 H236 2.1.1.170 0005737,0005829,0006364,0008168,0008649,0031167,0032259,0070043,0070476 Q9LCY2 19622680 304 MFHGKHPGGLSERGRALLLEGGKALGLDLKPHLEAFSRLYALLQEAGEEEVVVKHFLDSLTLLRLPLWQGPLRVLDLGTGAGFPGLPLKIVRPELELVLVDATRKKVAFVERAIEVLGLKGARALWGRAEVLAREAGHREAYARAVARAVAPLCVLSELLLPFLEVGGAAVAMKGPRVEEELAPLPPALERLGGRLGEVLALQLPLSGEARHLVVLEKTAPTPPAYPRRPGVPERHPLC 3g89 B 1.5 BS02 AMP B 1 R239 R245 H246 R228 R234 H235 2.1.1.170 0005737,0005829,0006364,0008168,0008649,0031167,0032259,0070043,0070476 Q9LCY2 19622680 304 MFHGKHPGGLSERGRALLLEGGKALGLDLKPHLEAFSRLYALLQEAEEEVVVKHFLDSLTLLRLPLWQGPLRVLDLGTGAGFPGLPLKIVRPELELVLVDATRKKVAFVERAIEVLGLKGARALWGRAEVLAREAGHREAYARAVARAVAPLCVLSELLLPFLEVGGAAVAMKGPRVEEELAPLPPALERLGGRLGEVLALQLPLSGEARHLVVLEKTAPTPPAYPRRPGVPERHPLC 3gc0 A 2.0 BS01 AMP A 1 G24 V29 A42 K44 Y93 A94 L143 G14 V19 A32 K34 Y76 A77 L126 D136 K138 Q140 N141 D159 T179 D119 K121 Q123 N124 D138 T149 ? 0000082,0000307,0004672,0004674,0004693,0005524,0005634,0005737,0006468,0007165,0010389,0010468,0016310,0030332 A8BZ95 21904054 309 SIDRYRRITKLGEGTYGEVYKAIDTVTNETVAIKRIRLEHTAIREVSLLKELQHRNIIELKSVIHHNHRLHLIFEYAENDLKKYMDKNPDVSMRVIKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSVETPVLKIGDFGLARAFEIITLWYRPPEILLGSRHYSTSVDIWSIACIWAEMLMKTPLFPGDSEIDQLFKIFEVLGLPDDTTWPGVTALPDWKQSFPKFRGKTLKRVLGALLDDEGLDLLTAMLEMDPVKRISAKNALEHPYFSHNDFDP 3glv B 1.99 BS01 AMP B 1 G8 V9 F10 H14 G16 H17 Y20 G91 Y92 D93 Q94 K119 Y120 G9 V10 F11 H15 G17 H18 Y21 G92 Y93 D94 Q95 K120 Y121 N44 K46 N45 K47 2.7.7.2 0003824,0003919,0005524,0006747,0009058,0016779,0046444 Q979C2 201 GMIRVMATGVFDILHLGHIHYLKESKKLGDELVVVVARDSTARNNGKIPIFDENSRLALISELKVVDRAILGHEGDMMKTVIEVKPDIITLGYDQKFDEAELQSKINKLGITVKIVRISKYD 3gru A 1.6 BS01 AMP A 1 E59 I60 D84 A85 P103 E50 I51 D75 A76 P94 G38 E59 N101 Y104 F167 G29 E50 N92 Y95 F158 2.1.1.- 0000154,0000179,0003723,0005737,0006364,0008168,0016433,0016740,0031167,0032259 Q58435 20163168 300 QCFLIDKNFVNKAVESANLTKDDVVLEIGLGKGILTEELAKNAKKVYVIEIDKSLEPYANKLKELYNNIEIIWGDALKVDLNKLDFNKVVANLPYQISSPITFKLIKRGFDLAVLMYQYEFAKRMVAAAGTKDYGRLSVAVQSRADVEIVAKVPPSAFYPKPKVYSAIVKIKPNKGKYHIENENFFDDFLRAIFQHRNKSVRKALIDSSKELNYNKDEMKKILEDFLNTNSEIKNLINEKVFKLSVKDIVNLSNEFYRFLQNR 3hf7 A 2.75 BS01 AMP A 1 I214 V215 H235 G236 T317 D320 I14 V15 H35 G36 T117 D120 ? A6TCM0 1 KVSVNDIMVPRNEIVGIDINDDWKSIVRQLTHSPHGRIVLYRDSLDDAISMLRVREAYRLMTEKKEFTKEIMLRAADEIYFVPEGTPLSTQLVKFQRNKKKVGLVVDEYGDIQGLVTVEDILEEIVG 3hw5 A 1.81 BS02 AMP A 1 A20 I38 H41 L42 E80 G81 D108 K134 A24 I42 H45 L46 E59 G60 D87 K113 3.1.-.- 0003723,0039694 Q9Q0U9 19587036 257 PLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHTYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGE 3i0q A 2.8 BS01 AMP A 1 F50 F102 I103 I229 D230 F40 F92 I93 I219 D220 ? 0000166,0016740,0046872 O06916 20089863 400 PIQAQQLIELLKVHYGIDIHTAQFIQAFAYQADSESKSYFIKLKYGYHDEINLSIIRLLHDSGIKEIIFPIHTLEAKLFQQLKHFKIIAYPFIHAPNGFTQNLTGKQWKQLGKVLRQIHETSVPISIQQQLRKEIYSPKWREIVRSFYNQIEFDNSDDKLTAAFKSFFNQNSAAIHRLVDTSEKLSKKIQPDLDKYVLCHSDIHAGNVLVGNEESIYIIDWDEPMLAPKERDLMFIGGGVGNVWNKPHEIQYFYEGYGEINVDKTILSYYRHERIVEDIAVYGQDLLNQSRLESFKYFKEMFDPNNVVEIAFATEQ 3ib8 A 1.8 BS03 AMP A 1 H23 D63 N97 H98 M179 A180 V183 H207 H20 D60 N94 H95 M176 A177 V180 H204 3.1.4.16,3.1.4.17 0000166,0004112,0004115,0005506,0005515,0005576,0005737,0005886,0008199,0008663,0009274,0016787,0030145,0030313,0042301,0042545,0046872,0047555 P9WP65 19801656 666 LRAAEHPRPDYVLLHISDTHLIGGDRRLYGAVDADDRLGELLEQLNQSGLRPDAIVFTGDLADKGEPAAYRKLRGLVEPFAAQLGAELVWVMGNHDDRAELRKFLLDEAPSMAPLDRVCMIDGLRIIVLDTSVPGHHHGEIRASQLGWLAEELATPAPDGTILALHHPPIPSVLDMAVTVELRDQAALGRVLRGTDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVAAGGTRGRDGAQGCNLVHVYPDTVVHSVIPLGGGETVGTFVSPGQARRKIAESGIFIEPSRRD 3ifa A 1.93 BS01 AMP A 1 G21 A24 T27 L30 K112 Y113 R140 T177 G14 A17 T20 L23 K103 Y104 R131 T167 D74 E97 E98 D118 L120 D121 E280 D65 E88 E89 D109 L111 D112 E270 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 O00757 22120740 339 TDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGSVNVDQVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTSDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQA 3ifa B 1.93 BS01 AMP B 1 V17 K20 G21 A24 G26 T27 E29 L30 K112 Y113 T177 V10 K13 G14 A17 G19 T20 E22 L23 K98 Y99 T162 D74 E97 E98 D118 L120 D121 E280 D60 E83 E84 D104 L106 D107 E265 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 O00757 22120740 339 TDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGQVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTSDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQA 3ifa C 1.93 BS01 AMP C 1 K20 G21 A24 G26 T27 E29 L30 K112 Y113 T177 K12 G13 A16 G18 T19 E21 L22 K99 Y100 T163 D74 E97 E98 D118 L120 D121 E280 D61 E84 E85 D105 L107 D108 E266 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 O00757 22120740 339 DMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGSVQVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTSDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQ 3ifa D 1.93 BS01 AMP D 1 V17 K20 G21 A24 G26 T27 E29 L30 K112 Y113 R140 T177 V9 K12 G13 A16 G18 T19 E21 L22 K100 Y101 R128 T163 D74 E97 E98 D118 L120 D121 E280 D62 E85 E86 D106 L108 D109 E266 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 O00757 22120740 339 DMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGSVNVVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTSEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQA 3ifc A 1.97 BS01 AMP A 1 V17 K20 G21 A24 T27 L30 K112 Y113 R140 T177 V9 K12 G13 A16 T19 L22 K98 Y99 R126 T163 D74 E97 E98 D118 L120 D121 E280 D60 E83 E84 D104 L106 D107 E266 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 O00757 22120740 339 DMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGSQVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTSEDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQAG 3ifc B 1.97 BS01 AMP B 1 V17 K20 G21 A24 G26 T27 E29 L30 K112 Y113 T177 V9 K12 G13 A16 G18 T19 E21 L22 K97 Y98 T161 D74 E97 E98 D118 L120 D121 E280 D59 E82 E83 D103 L105 D106 E264 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 O00757 22120740 339 DMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGQVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTSDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQA 3ifc C 1.97 BS01 AMP C 1 V17 K20 G21 A24 G26 T27 E29 L30 K112 Y113 T177 V9 K12 G13 A16 G18 T19 E21 L22 K98 Y99 T163 D74 E97 E98 D118 L120 D121 E280 D60 E83 E84 D104 L106 D107 E266 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 O00757 22120740 339 DMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGSQVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTSEDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQ 3ifc D 1.97 BS01 AMP D 1 V17 K20 G21 A24 G26 T27 G28 E29 L30 K112 Y113 R140 T177 V9 K12 G13 A16 G18 T19 G20 E21 L22 K96 Y97 R124 T160 D74 E97 E98 D118 L120 D121 E280 D58 E81 E82 D102 L104 D105 E263 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 O00757 22120740 339 DMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTSDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQA 3iuy A 2.4 BS01 AMP A 1 I251 Q258 G278 G280 K281 T282 L283 H320 E324 I40 Q47 G67 G69 K70 T71 L72 H100 E104 3.6.4.13 0003676,0005524 Q86TM3 20941364 160 MTCDDLKSGEKRLIPKPTCRFKDAFQQYPDLLKSIIRVGILKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDNGPGMLVLTPTRELALHVEAECSKYSYKGLKSICIYGQIEDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYV 3iuy B 2.4 BS01 AMP B 1 I251 K253 Q258 T277 G278 G280 K281 T282 H320 E324 I40 K42 Q47 T66 G67 G69 K70 T71 H101 E105 3.6.4.13 0003676,0005524 Q86TM3 20941364 160 MTCDDLKSGEKRLIPKPTCRFKDAFQQYPDLLKSIIRVGILKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSNGPGMLVLTPTRELALHVEAECSKYSYKGLKSICIYGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYV 3jtf A 2.0 BS01 AMP A 1 M88 D89 H109 S110 R111 T187 E189 D190 M14 D15 H35 S36 R37 T112 E114 D115 ? Q7WB69 1 ERTVADIMVPRSRMDLLDISQPLPQLLATIIETAHSRFPVYEDDRDNIIGILLAKDLLRYMLEPALDIRSLVRPAVFIPEVKRLNVLLREFRASRNHLAIVIDEGGISGLVTMEDVLEQIVGDI 3jtf B 2.0 BS01 AMP B 1 D89 H109 R111 T187 D190 D15 H35 R37 T113 D116 ? Q7WB69 1 ERTVADIMVPRSRMDLLDISQPLPQLLATIIETAHSRFPVYEDDRDNIIGILLAKDLLRYMLEPALDIRSLVRPAVFIPEVKRLNVLLREFRASRNHLAIVIDEHGGISGLVTMEDVLEQIVGDI 3jwp A 2.65 BS01 AMP A 1 S29 G30 E34 R41 G199 T200 S202 N225 I226 K243 F244 S28 G29 E33 R40 G198 T199 S201 N224 I225 K242 F243 P38 S39 F40 R41 N107 D109 H124 P37 S38 F39 R40 N106 D108 H123 2.3.1.- 0000781,0003677,0005515,0005634,0005677,0005694,0005730,0005737,0005739,0006338,0006355,0006476,0016233,0016740,0017136,0034979,0036049,0036054,0036055,0046872,0070403 Q8IE47 266 KKDTQSITLEELAKIIKKCKHVVALTGSGTSAESNIPSFRGSSNSIWSKYDPRIYGTIWGFWKYPEKIWEVIRDISSDYEIEINNGHVALSTLESLGYLKSVVTQNVDGLHEASGNTKVISLHGNVFEAVCCTCNKIVKLNKIMLQKTSHFMHQLPPECPCGGIFKPNIILFGEVVSSDLLKEAEEEIAKCDLLLVIGTSSTVSTATNLCHFACKKKKKIVEINISKTYITNKMSDYHVCAKFSELTKVANILKG 3kd6 A 1.88 BS01 AMP A 1 S8 D12 G27 F81 W83 R94 N125 M149 F151 W152 G234 D237 S8 D12 G27 F81 W83 R94 N125 M149 F151 W152 G234 D237 G234 A235 G236 D237 G234 A235 G236 D237 ? 0000166,0005829,0016301,0016310,0016772 Q8KDR9 509 LSLLVIGSLAFDDIETPFGRSDNTLGGSSTYIALSASYFTDEPIRMVGVVGSDFGKEHFDLLHAKNIDTRGIQVIEDGKTFRWAGRYHYDMNTRDTLDTQLNVFAEFDPHVPQYYRDSKFVCLGNIDPELQLKVLDQIDDPKLVVCDTMNFWIEGKPEELKKVLARVDVFIVNDSEARLLSGDPNLVKTARIIREMGPKTLIIKKGEHGALLFTDNGIFAAPAFPLESIYDPTGAGDTFAGGFIGHLARCGNTSEAEMRKAVLYGSAMASFCVEQFGPYRYNDLDLLEVDDRYQSFLELS 3kd6 B 1.88 BS01 AMP B 1 S8 D12 G27 F81 W83 R94 N125 M149 F151 W152 G234 D237 S7 D11 G26 F80 W82 R93 N124 M148 F150 W151 G233 D236 G234 A235 G236 D237 G233 A234 G235 D236 ? 0000166,0005829,0016301,0016310,0016772 Q8KDR9 509 SLLVIGSLAFDDIETPFGRSDNTLGGSSTYIALSASYFTDEPIRMVGVVGSDFGKEHFDLLHAKNIDTRGIQVIEDGKTFRWAGRYHYDMNTRDTLDTQLNVFAEFDPHVPQYYRDSKFVCLGNIDPELQLKVLDQIDDPKLVVCDTMNFWIEGKPEELKKVLARVDVFIVNDSEARLLSGDPNLVKTARIIREMGPKTLIIKKGEHGALLFTDNGIFAAPAFPLESIYDPTGAGDTFAGGFIGHLARCGNTSEAEMRKAVLYGSAMASFCVEQFGPYRYNDLDLLEVDDRYQSFLEL 3kgd A 1.68 BS01 AMP A 1 S129 A130 P131 F135 F251 Y284 D287 Q288 H309 S126 A127 P128 F132 F248 Y281 D284 Q285 H306 E14 H309 E11 H306 6.5.1.4 0003824,0003963,0005524,0005737,0006396,0016874 P46849 20399182 501 RMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICGATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASTAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERFLPVRFSLIETDGVTRVSIE 3kgd B 1.68 BS01 AMP B 1 S129 A130 P131 F135 F251 Y284 D287 Q288 H309 S132 A133 P134 F138 F254 Y287 D290 Q291 H312 E14 H309 E17 H312 6.5.1.4 0003824,0003963,0005524,0005737,0006396,0016874 P46849 20399182 501 HHHHHKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICGATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASTAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERFLPVRFSLIETDGVTRVSIE 3kgd C 1.68 BS01 AMP C 1 S129 A130 P131 F135 F251 Y284 D287 Q288 H309 S128 A129 P130 F134 F250 Y283 D286 Q287 H308 E14 H309 E13 H308 6.5.1.4 0003824,0003963,0005524,0005737,0006396,0016874 P46849 20399182 501 MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICGATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASTAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERFLPVRFSLIETDGVTRVSIE 3kgd D 1.68 BS01 AMP D 1 S129 A130 P131 F135 F251 Y284 D287 Q288 H309 S130 A131 P132 F136 F252 Y285 D288 Q289 H310 E14 H309 E15 H310 6.5.1.4 0003824,0003963,0005524,0005737,0006396,0016874 P46849 20399182 501 RHMKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICGATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASTAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERFLPVRFSLIETDGVTRVSIE 3kh5 A 2.1 BS02 AMP A 1 R181 T195 T197 D198 V233 I234 R179 T193 T195 D196 V231 I232 1.1.1.34 Q58622 20382158 282 VRVMKIAQNKKIVTVYPTTTIRKALMTMNENKYRRLPVVNAGNNKVVGIITSMDIVDFMGGGSKYNLIREKHERNFLAAINEPVREIMEENVITLKENADIDEAIETFLTKNVGGAPIVNDENQLISLITERDVIRALLDKIDENEVIDDYITRDVIVATPGERLKDVARTMVRNGFRRLPVVSEGRLVGIITSTDFIKLLGSDWAFNHMQTGNVREITNVRMEEIMKRDVITAKEGDKLKKIAEIMVTNDIGALPVVDENLRIKGIITEKDVLKYFA 3kh5 A 2.1 BS05 AMP A 2 N68 L69 E72 K73 E88 N66 L67 E70 K71 E86 1.1.1.34 Q58622 20382158 1605 VRVMKIAQNKKIVTVYPTTTIRKALMTMNENKYRRLPVVNAGNNKVVGIITSMDIVDFMGGGSKYNLIREKHERNFLAAINEPVREIMEENVITLKENADIDEAIETFLTKNVGGAPIVNDENQLISLITERDVIRALLDKIDENEVIDDYITRDVIVATPGERLKDVARTMVRNGFRRLPVVSEGRLVGIITSTDFIKLLGSDWAFNHMQTGNVREITNVRMEEIMKRDVITAKEGDKLKKIAEIMVTNDIGALPVVDENLRIKGIITEKDVLKYFA 3l2p A 3.0 BS04 AMP A 1 E419 K421 Y422 F508 K573 W586 K588 K590 E237 K239 Y240 F326 K391 W404 K406 K408 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P49916 20518483 901 HMRHKDCLLREFRKLCAMVADNPSYNTKTQIIQDFLRKGGDVYLTVKLLLPGVIKTVYNLNDKQIVKLFSRIFNCNPDDMARDLEQGDVSETIRVFFEQSKSFPPAAKSLLTIQEVDEFLLRLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEVELSVQASLMTPVQPMLAEACKSVEYAMKKCPNGMFSEIKYDGERVQVHKNGDHFSYFSRSLKPVLPHKVAHFKDYIPQAFPGGHSMILDSEVLLIDNKTGKPLPFGTLGVHKKAAFQDANVCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEMKRVTKALDLADMITRVIQEGLEGLVLKDVKGTYEPGKRHWLKVKKDYLNMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPGSQKWCTVTKCAGGHDDATLARLQNELDMVKISKAAVWEITGAEFSKSEAHTADGISIRFPRCTRIRDDKDWKSATNLPQLKELYQLSK 3l31 A 2.3 BS01 AMP A 1 S116 N119 T253 V258 Y278 S51 N54 T188 V193 Y213 3.6.1.1 Q8XIQ9 20303981 1 VKLKVEDLEMDKIAPLAPEVSLKMAWNIMRDKNLKSIPVADGNNHLLGMLSTSNITATYMDIWDSNILAKSATSLDNILDTLSAEAQNINEERKVFPGKVVVAAMQAESLKEFISEGDIAIAGDRAEIQAELIELKVSLLIVTGGHTPSKEIIELAKKNNITVITTPHDSFTASRLIVQSLPVDYVMTKDNLVAVSTDDLVEDVKVTMSETRYSNYPVIDENNKVVGSIARFHL 3l31 B 2.3 BS01 AMP B 1 M114 S116 N119 T253 V258 Y278 M47 S49 N52 T186 V191 Y211 3.6.1.1 Q8XIQ9 20303981 1 LKVEDLEMDKIAPLAPEVSLKMAWNIMRDKNLKSIPVADGNNHLLGMLSTSNITATYMDIWDSNILAKSATSLDNILDTLSAEAQNINEERKVFPGKVVVAAMQAESLKEFISEGDIAIAGDRAEIQAELIELKVSLLIVTGGHTPSKEIIELAKKNNITVITTPHDSFTASRLIVQSLPVDYVMTKDNLVAVSTDDLVEDVKVTMSETRYSNYPVIDENNKVVGSIARFH 3l4b A 3.45 BS01 AMP A 1 G14 G16 R17 D37 K38 D58 A59 T80 N81 R105 G8 G10 R11 D31 K32 D52 A53 T74 N75 R99 ? 0000166,0005886,0006813,0015079,0071805 D3KFX7 144 SKYIVIFGCGRLGSLIANLASSSGHSVVVVDKNEYAFHRLNSEFSGFTVVGDAAEFETLKECGMEKADMVFAFTNDDSTNFFISMNARYMFNVENVIARVYDPEKIKIFEENGIKTICPAVLMIEKVKEFI 3l4b B 3.45 BS01 AMP B 1 G16 R17 D37 K38 G57 D58 A59 T80 N81 R105 G10 R11 D31 K32 G51 D52 A53 T74 N75 R99 ? 0000166,0005886,0006813,0015079,0071805 D3KFX7 144 SKYIVIFGCGRLGSLIANLASSSGHSVVVVDKNEYAFHRLNSEFSGFTVVGDAAEFETLKECGMEKADMVFAFTNDDSTNFFISMNARYMFNVENVIARVYDPEKIKIFEENGIKTICPAVLMIEKVKE 3l4b E 3.45 BS01 AMP E 1 G16 R17 D37 K38 A59 T80 N81 R105 G8 R9 D29 K30 A46 T67 N68 R92 ? 0000166,0005886,0006813,0015079,0071805 D3KFX7 144 YIVIFGCGRLGSLIANLASSSGHSVVVVDKNEYAFHFSGFTVVGDAAEFETLKECGMEKADMVFAFTNDDSTNFFISMNARYMFNVENVIARVYDPEKIKIFEENGIKTICPAVLMIEKVKEFII 3l4b F 3.45 BS01 AMP F 1 G16 R17 D37 K38 G57 D58 A59 T80 N81 R105 G9 R10 D30 K31 G50 D51 A52 T73 N74 R98 ? 0000166,0005886,0006813,0015079,0071805 D3KFX7 144 KYIVIFGCGRLGSLIANLASSSGHSVVVVDKNEYAFHRLNSEFSGFTVVGDAAEFETLKECGMEKADMVFAFTNDDSTNFFISMNARYMFNVENVIARVYDPEKIKIFEENGIKTICPAVLMIEKVKE 3l9w A 1.75 BS02 AMP A 1 G408 R409 F410 D429 H430 H434 D449 A450 I471 D472 R496 G10 R11 F12 D31 H32 H36 D51 A52 I73 D74 R98 G1107 F1113 H1118 G271 F277 H282 ?,1.6.5.2 0003955,0005515,0005886,0006813,0008753,0009055,0010181,0015079,0016491,0032414,0042803,0050136,0051453,0051454,1901381,1903103 P03819,P0A754 21041667 2401 GMRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVGMILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAH 3l9w B 1.75 BS02 AMP B 1 G408 R409 F410 D429 H434 A450 I471 D472 R496 G10 R11 F12 D31 H36 A52 I73 D74 R98 G1107 F1113 H1118 G290 F296 H301 ?,1.6.5.2 0003955,0005515,0005886,0006813,0008753,0009055,0010181,0015079,0016491,0032414,0042803,0050136,0051453,0051454,1901381,1903103 P03819,P0A754 21041667 2401 GMRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSGMILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAH 3lc6 B 3.1 BS01 AMP B 1 S101 N104 S105 H113 I123 K291 K294 F375 N377 S100 N103 S104 H111 I121 K284 K287 F360 N362 2.7.11.5,3.1.3.- 0004674,0004721,0005524,0005737,0006006,0006097,0006099,0006470,0008772,0016208,0016310,0016788,0016791,0018105,0050790 Q8X607 20505668 1604 PRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLDHRSLTPERLFIFSSQPTIPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYG 3lcb A 2.9 BS01 AMP A 1 N104 S105 H113 L116 K294 T295 Y298 F375 N377 N95 S96 H104 L107 K277 T278 Y281 F358 N360 2.7.11.5,3.1.3.- 0004674,0004721,0005524,0005737,0006006,0006097,0006099,0006470,0008772,0016208,0016310,0016788,0016791,0018105,0050790 Q8X607 20505668 1604 GLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSV 3lcb B 2.9 BS02 AMP B 1 N104 S105 H113 L116 K291 K294 T295 Y298 F375 N377 N94 S95 H103 L106 K281 K284 T285 Y288 F365 N367 2.7.11.5,3.1.3.- 0004674,0004721,0005524,0005737,0006006,0006097,0006099,0006470,0008772,0016208,0016310,0016788,0016791,0018105,0050790 Q8X607 20505668 1604 LELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSV 3lfr A 1.53 BS01 AMP A 1 I74 H94 S95 T175 D178 I14 H34 S35 T115 D118 ? Q87VX8 1 LQVRDIMVPRSQMISIKATQTPREFLPAVIDAAHSRYPVIGESHDDVLGVLLAKDLLPLILKADGDSDDVKKLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLVTIEDVLEQI 3lfr B 1.53 BS01 AMP B 1 I74 H94 S95 T175 D178 I16 H36 S37 T115 D118 ? Q87VX8 2 ADLQVRDIMVPRSQMISIKATQTPREFLPAVIDAAHSRYPVIGESHDDVLGVLLAKDLLPLILKAGDSDVKKLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLVTIEDVLEQIVGDIE 3lfz A 2.2 BS04 AMP A 1 N68 L69 E72 K73 E88 N68 L69 E72 K73 E88 ? Q58622 20382158 284 MFVRVMKIAQNKKIVTVYPTTTIRKALMTMNENKYRRLPVVNAGNNKVVGIITSMDIVDFMGGGSKYNLIREKHERNFLAAINEPVREIMEENVITLKENADIDEAIETFLTKNVGGAPIVNDENQLISLITERDVIRALLDKIDENEVIDDYITRDVIVATPGERLKDVARTMVRNGFRRLPVVSEGRLVGIITSTDFIKLLGSDWAFNHMQTGNVREITNVRMEEIMKRDVITAKEGDKLKKIAEIMVTNDIGALPVVDENLRIKGIITEKDVLKYFA 3lhh A 2.1 BS01 AMP A 1 V53 H73 S74 T152 D155 V13 H33 S34 T112 D115 ? Q8EDE1 171 TISSLMVPRSDIVFLDLNLPLDANLRTVMQSPHSRFPVCRNNVDDMVGIISAKQLLSESIAGERLELVDLVKNCNFVPNSLSGMELLEHFRTTGSQMVFVVDEYGDLKGLVTLQDMMDALTGEFF 3lkm A 1.6 BS06 AMP A 1 F586 A587 R592 K645 E713 L716 F720 D766 F31 A32 R37 K87 E153 L156 F160 D206 2.7.11.7 0004674,0005524,0006468 P42527 20197546 907 TGEMGILWEFDPIINKWIRLSMKLKVERKPFAEGALREAYHTVSLGVGTDENYPLGKLFPPIEMISPISKNNEAMTQLKNGTKFVLKLYKKEQQASRELYFEDVKMQMVCRDWGNKFNQKKPPKKIEFLMSWVVELIDRSPSSNGQPILCSIEPLLVGEFKKNNSNYGAVLTNRSTPQAFSHFTYELSNKQMIVVDIQGVDDLYTDPQIHTPDGKGFGLGNLGKAGINKFITTHKCNAVCALLDLDV 3loq A 2.32 BS01 AMP A 1 P4 T5 D6 N10 S11 V34 M105 G106 R108 S120 V121 S122 P12 T13 D14 N18 S19 V42 M108 G109 R111 S123 V124 S125 E16 E24 ? 0000166 O28514 271 NLYFQSNAMLLPTDLSENSFKVLEYLGDFKKVGVEEIGVLFVINLTKLGIDIDHYIDEMSEKAEEVLPEVAQKIEAAGIKAEVIKPFPAGDPVVEIIKASENYSFIAMGSRGASKFKKILLGSVSEGVLHDSKVPVYIFKHDMVVNSLFDRVLVAYDFSKWADRALEYAKFVVKKTGGELHIIHVSEDGDKTADLRVMEEVIGAEGIEVHVHIESGTPHKAILAKREEINATTIFMGSRGAGSVMTMILGSTSESVIRRSPVPVFVCKRGDDE 3loq B 2.32 BS01 AMP B 1 P4 T5 D6 S11 V34 M105 G106 R108 G119 V121 S122 P9 T10 D11 S16 V39 M104 G105 R107 G118 V120 S121 E16 E21 ? 0000166 O28514 271 FQSNAMLLPTDLSENSFKVLEYLGDFKKVGVEEIGVLFVINLTKLSDIDHYIDEMSEKAEEVLPEVAQKIEAAGIKAEVIKPFPAGDPVVEIIKASENYSFIAMGSRGASKFKKILLGSVSEGVLHDSKVPVYIFKHDMVVNSLFDRVLVAYDFSKWADRALEYAKFVVKKTGGELHIIHVSEDGDKTADLRVMEEVIGAEGIEVHVHIESGTPHKAILAKREEINATTIFMGSRGAGSVMTMILGSTSESVIRRSPVPVFVCKRG 3loq B 2.32 BS02 AMP B 2 A152 Y153 D154 V182 M233 G234 T249 S250 A151 Y152 D153 V181 M232 G233 T248 S249 E16 E21 ? 0000166 O28514 272 FQSNAMLLPTDLSENSFKVLEYLGDFKKVGVEEIGVLFVINLTKLSDIDHYIDEMSEKAEEVLPEVAQKIEAAGIKAEVIKPFPAGDPVVEIIKASENYSFIAMGSRGASKFKKILLGSVSEGVLHDSKVPVYIFKHDMVVNSLFDRVLVAYDFSKWADRALEYAKFVVKKTGGELHIIHVSEDGDKTADLRVMEEVIGAEGIEVHVHIESGTPHKAILAKREEINATTIFMGSRGAGSVMTMILGSTSESVIRRSPVPVFVCKRG 3lq3 A 1.42 BS04 AMP A 1 L82 L102 Y147 I148 L249 L36 L56 Y101 I102 L203 2.7.1.32,2.7.1.82 0004103,0004305,0005524,0005737,0005829,0006646,0006656,0006657,0007517,0008654,0016301,0016310 Q9Y259 20299452 402 SRDAERRAYQWCREYLGGAWRRVQPEELRVYPVNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPVLSAAIATKMAQFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPTGLPEMNLLEMYSLKDEMGNLRKLLESTPSPVVFCHNDIQEGNILLLSEPDSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQASMSTIEFGYLDYAQSRFQFYFQQKGQL 3lud A 2.095 BS01 AMP A 1 G524 K525 T526 Y529 K533 Q545 C546 Q548 K570 G85 K86 T87 Y90 K94 Q106 C107 Q109 K131 3.1.26.n2 0003676 Kd=0.26mM Q9UKV8 20505670 600 KQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLG 3lud B 2.095 BS01 AMP B 1 G524 T526 Y529 K533 Q545 C546 Q548 K570 G85 T87 Y90 K94 Q106 C107 Q109 K131 3.1.26.n2 0003676 Kd=0.26mM Q9UKV8 20505670 600 KQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKL 3lud C 2.095 BS01 AMP C 1 G524 K525 T526 Y529 K533 Q545 C546 Q548 K566 G85 K86 T87 Y90 K94 Q106 C107 Q109 K127 3.1.26.n2 0003676 Kd=0.26mM Q9UKV8 20505670 600 KQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLG 3lw7 B 2.3 BS01 AMP B 1 K21 M38 S39 L56 M57 A60 R64 G92 R94 E98 R144 E148 K14 M31 S32 L49 M50 A53 R57 G85 R87 E91 R129 E133 ? 0005524 Q97Z90 189 IKVILITGMPGSGKSEFAKLLKERGAKVIVMSDVVRKRYSIEAKPGERLMDFAKRLREIYGDGVVARLCVEELGTSNHDLVVFDGVRSLAEVEEFKRLLGDSVYIVAVHSPPKIRYKRMIEEISELIRRDREELKLGIGEVIAMADYIITNDSNYEEFKRRCEEVTDRVL 3m84 A 1.699 BS01 AMP A 1 S41 D107 G140 E141 S42 D108 G141 E142 6.3.3.1 0004637,0004641,0005524,0005737,0005829,0006164,0006189,0016874,0046084 Q5NGF2 354 AMAGLKYEDAGVNIEAGNQAVERMKQHVKKTFTQDVLTGLGSFGSLYSLKNIINNYDDPVLVQSIDGVGTKTKVAVMCGKFENLGYDLFSAATNDIVVMGAKPITFLDYVAHDKLDPAIMEELVKGMSKACAECGVSLVGGETAEMPGVYQAGEIDMVGVITGIVDRKRIINGENIKEGDIVFGLSSSGLHTNGYSFARKLFFDVAGNKHTDTYPELEGKTIGDVLLEPHINYTNIIHDFLDNGVDIKGMAHITGGGFIENIPRVLPQGLGAQIDKDSFATPAIFKLMQRIGDISEFEMYRSFNMGIGMTIIASQDQFDKMQELAKKHTNTKLYQIGKITNSGKVEII 3mf2 A 2.15 BS02 AMP A 1 R159 E161 L169 F172 M174 K235 A250 C251 S253 G283 R286 R143 E145 L153 F156 M158 K219 A234 C235 S237 G267 R270 C131 R159 E161 R168 E176 K235 A250 S253 C279 R286 C115 R143 E145 R152 E160 K219 A234 S237 C263 R270 6.2.1.n2 0000166,0004812,0005515,0005524,0006418,0016874,0046872 Q89VT8 20663952 1010 ADPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSHREAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVCGLHGTEREINAAVSRFDAGGDWTTSLSPADLVLSPAACYPVYPIAASRGPLPKGGLRFDVAADCFRREPSKHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDYASDPFFGRVGQMKAVSQKQQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGEPAHTGCVAFGMDRLAVAMFHTHGTDLSAWPAKVRDILGLQPH 3mf2 B 2.15 BS02 AMP B 1 R159 L169 F172 K235 A250 C251 M252 G283 R286 R142 L152 F155 K218 A233 C234 M235 G266 R269 C131 R159 E161 R168 E176 K235 A250 S253 C279 R286 C114 R142 E144 R151 E159 K218 A233 S236 C262 R269 6.2.1.n2 0000166,0004812,0005515,0005524,0006418,0016874,0046872 Q89VT8 20663952 1010 DPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSHREAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVCGLHGTEREINAAVSRFDAGGDWTTSLSPADLVLSPAACYPVYPIAASRGPLPKGGLRFDVAADCFRREPSKHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDYASDPFFGRVGQMKAVSQKQQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGEPAHTGCVAFGMDRLAVAMFHTHGTDLSAWPAKVRDILGLQ 3n8h A 2.001 BS02 AMP A 1 M29 H33 G35 H36 L39 L146 G147 K149 D150 T175 Q176 L184 M30 H34 G36 H37 L40 L147 G148 K150 D151 T176 Q177 L185 M29 H33 H36 Q76 D77 I80 K149 S185 S186 R187 M30 H34 H37 Q77 D78 I81 K150 S186 S187 R188 6.3.2.1 0003824,0004592,0005524,0005737,0005829,0009058,0015940,0016874 Q5NF57 270 AMIIADNIKQFHSIRNSLIKQQKIGFVPTMGALHNGHISLIKKAKSENDVVIVSIFVNPTQFNNPNDYQTYPNQLQQDIQILASLDVDVLFNPSEKDIYPDGNLLRIEPKLEIANILEGKSRPGHFSGMLTVVLKLLQITKPNNLYLGEKDYQQVMLIKQLVKDFFINTKIIVCPTQRQPSGLPLSSRNKNLTSTDIEIANKIYEILRQDDFSNLEELTNKINSTGAKLQYIQKLNNRIFLAFYIGKVRLIDNFLKETGPSC 3n8h B 2.001 BS02 AMP B 1 P27 M29 H33 G35 H36 L39 L146 G147 D150 T175 Q176 L184 P28 M30 H34 G36 H37 L40 L147 G148 D151 T176 Q177 L185 M29 H33 H36 Q76 D77 I80 K149 S185 S186 R187 M30 H34 H37 Q77 D78 I81 K150 S186 S187 R188 6.3.2.1 0003824,0004592,0005524,0005737,0005829,0009058,0015940,0016874 Q5NF57 270 AMIIADNIKQFHSIRNSLIKQQKIGFVPTMGALHNGHISLIKKAKSENDVVIVSIFVNPTQFNNPNDYQTYPNQLQQDIQILASLDVDVLFNPSEKDIYPDGNLLRIEPKLEIANILEGKSRPGHFSGMLTVVLKLLQITKPNNLYLGEKDYQQVMLIKQLVKDFFINTKIIVCPTQRQPSGLPLSSRNKNLTSTDIEIANKIYEILRQDDFSNLEELTNKINSTGAKLQYIQKLNNRIFLAFYIGKVRLIDNFLKETGPSC 3ngn A 2.4 BS01 AMP A 1 H360 W363 P365 K371 D410 N412 N479 F484 H529 H177 W180 P182 K188 D215 N217 N263 F268 H313 3.1.13.4 0003824,0004535 Q96LI5 20628353 556 LPPRPWITLKERDSASFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEIVNCDADIISLQEVETEQYFTLFLPALKERGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMANSDGSEAMLNRVMTKDNIGVAVVLEVHKELFKQLLIVANAHMHWDPEYSDVKLIQTMMFVSEVKNILEKASIPLVLCADLNSLPDSGVVEYLSNGGVADNHKDFKERITHGFQLKSAYENNLMPYTNYTFDFKGVIDYIFYSKTHMNVLGVLGPLDPQWLVENNITGCPHPHIPSDHFSLLTQLELHP 3ngn A 2.4 BS02 AMP A 2 I271 M272 S273 E276 I99 M100 S101 E104 3.1.13.4 0003824,0004535 Q96LI5 20628353 557 LPPRPWITLKERDSASFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEIVNCDADIISLQEVETEQYFTLFLPALKERGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMANSDGSEAMLNRVMTKDNIGVAVVLEVHKELFKQLLIVANAHMHWDPEYSDVKLIQTMMFVSEVKNILEKASIPLVLCADLNSLPDSGVVEYLSNGGVADNHKDFKERITHGFQLKSAYENNLMPYTNYTFDFKGVIDYIFYSKTHMNVLGVLGPLDPQWLVENNITGCPHPHIPSDHFSLLTQLELHP 3ngt A 2.57 BS01 AMP A 1 K11 Y51 L54 F59 L63 V111 H117 K10 Y50 L53 F58 L62 V110 H116 K11 Y51 N114 H117 E128 K10 Y50 N113 H116 E127 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 SSERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDLCSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIYE 3ngt B 2.57 BS01 AMP B 1 K11 Y51 F59 T93 V111 N114 H117 K8 Y48 F56 T90 V108 N111 H114 K11 Y51 N114 H117 E128 K8 Y48 N111 H114 E125 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 ERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDLCSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIYE 3ngt C 2.57 BS01 AMP C 1 K11 Y51 F59 T93 V111 H117 K8 Y48 F56 T90 V108 H114 K11 Y51 N114 H117 E128 K8 Y48 N111 H114 E125 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 ERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDLCSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIYE 3ngt D 2.57 BS01 AMP D 1 Y51 F59 V111 H117 Y50 F58 V110 H116 K11 Y51 N114 H117 E128 K10 Y50 N113 H116 E127 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 SSERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDLCSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIYE 3ngt E 2.57 BS01 AMP E 1 K11 Y51 L54 F59 V111 H117 K10 Y50 L53 F58 V110 H116 K11 Y51 N114 H117 E128 K10 Y50 N113 H116 E127 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 SSERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDLCSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIYE 3ngt F 2.57 BS01 AMP F 1 K11 Y51 F59 V111 H117 K10 Y50 F58 V110 H116 K11 Y51 N114 H117 E128 K10 Y50 N113 H116 E127 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 SSERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDLCSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIYE 3ngt G 2.57 BS01 AMP G 1 K11 Y51 F59 L63 V111 H117 K9 Y49 F57 L61 V109 H115 K11 N114 H117 E128 K9 N112 H115 E126 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 SERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDLCSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIYE 3ngt H 2.57 BS01 AMP H 1 K11 Y51 F59 T93 V111 H117 K9 Y49 F55 T89 V107 H113 K11 N114 H117 E128 K9 N110 H113 E124 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 SERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIYE 3ngt I 2.57 BS01 AMP I 1 K11 F59 L63 T93 V111 H117 K10 F58 L62 T92 V110 H116 K11 N114 H117 E128 K10 N113 H116 E127 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 SSERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDLCSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIYE 3ngt J 2.57 BS01 AMP J 1 K11 Y51 F59 V111 H117 K9 Y49 F57 V109 H115 K11 N114 H117 E128 K9 N112 H115 E126 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 SERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDLCSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIY 3ngt K 2.57 BS01 AMP K 1 F59 L63 T93 N114 H117 F57 L61 T91 N112 H115 K11 N114 H117 E128 K9 N112 H115 E126 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 SERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDLCSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIYE 3ngt M 2.57 BS01 AMP M 1 K11 Y51 F59 T93 V111 H117 K9 Y49 F57 T91 V109 H115 K11 Y51 N114 H117 E128 K9 Y49 N112 H115 E126 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 SERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDLCSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIYE 3ngt N 2.57 BS01 AMP N 1 K11 Y51 L54 F59 T93 V111 N114 H117 K10 Y50 L53 F58 T92 V110 N113 H116 K11 Y51 N114 H117 E128 K10 Y50 N113 H116 E127 2.7.4.6 0004550,0005524,0005737,0006183,0006228,0006241,0009142,0016301,0016310,0097014 Q9U1E1 21528129 152 SSERTFIAVKPDGVQRGLVGEIIARFERKGYKLVALKILQPTTEQAQGHYKDLCSKPFFPALVKYFSSGPIVCMVWEGKNVVKSGRVLLGATNPADSQPGTIRGDFAVDVGRNVCHGSDSVESAEREIAFWFKADEIASWTSHSVSQIYE 3nkv A 1.7 BS03 AMP A 1 F45 W62 Y77 F42 W59 Y74 Q67 Q64 3.6.5.2 0003924,0005525 Q9H0U4 20651120 600 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKRM 3nkv B 1.7 BS03 AMP B 1 F45 W62 Y77 F42 W59 Y74 Q67 Q64 3.6.5.2 0003924,0005525 Q9H0U4 20651120 600 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASNVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKRM 3nqr A 2.0 BS01 AMP A 1 I74 M79 I80 H100 S101 T180 D183 I8 M13 I14 H34 S35 T114 D117 ? P0A2L3 1 QRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRTAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 3nqr B 2.0 BS01 AMP B 1 I80 H100 M165 T180 E182 D183 I16 H36 M98 T113 E115 D116 ? P0A2L3 2 ADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDHIEGILMAKDLLPFMRSDAAFSMDKVLRTAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 3nqr C 2.0 BS01 AMP C 1 I74 M79 I80 H100 S101 R102 M165 T180 D183 I9 M14 I15 H35 S36 R37 M100 T115 D118 ? P0A2L3 3 DQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRTAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 3nqr D 2.0 BS01 AMP D 1 I74 I80 H100 S101 R102 D183 I8 I14 H34 S35 R36 D117 ? P0A2L3 4 QRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRTAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 3nrn A 2.1 BS01 AMP A 1 G7 L29 E30 K31 G37 R38 V212 N238 V239 G7 L29 E30 K31 G37 R38 V204 N230 V231 ? 0000166,0016491 Q8U1X1 422 MRAVVVGAGLGGLLAGAFLARNGHEIIVLEKSAMIGGRFTNLPYKGFQLSTGALHMIPHGEDGPLAHLLRILGAKVEIVNSNPKGKILWEGKIFHYRESWKFLSKLLAEIRMNKLPKEEIPADEWIKEKIGENEFLLSVLESFAGWADSVSLSDLTALELAKEIRAALRWGGPGLIRGGCKAVIDELERIIMENKGKILTRKEVVEINIEEKKVYTRDNEEYSFDVAISNVGVRETVKLIGRDYFDRDYLKQVDSIEPSEGIKFNLAVPGEPRIGNTIVFTPGLMINGFNEPSALDKSLAREGYTLIMAHMALKNGNVKKAIEKGWEELLEIFPEGEPLLAQVYHIEWPLNEVLVVGDGYRPPGGIEVDGIALGVMKALEKLNLGSFSEWYL 3nua A 1.4 BS02 AMP A 1 R95 S101 D176 K178 T198 C199 R200 R96 S102 D177 K179 T199 C200 R201 6.3.2.6 0004639,0005524,0006164,0006189,0009236,0016874 Q0TTB4 242 AMVNQLEMLYEGKAKKIYATDKEDMVIVHYKDDATAFNGEKKAQIESKGVLNNEITSLIFEMLNKEGIKTHFVEKLNDRDQLCKKVEIVPLEVIVRNVAAGSMAKRLGLEEGYELKTTVFELSYKDDSLGDPLINDYHAVGIGATTFEELNKIYEITAKVNEILKEAFKKQNINLIDFKLEFGRYNGEILLADEISPDTCRFWDATTGEKMDKDRFRRDMGNVINGYREVLNRLRN 3nyo A 2.92 BS01 AMP A 1 K194 G195 V200 A213 K215 M266 D270 L318 D329 K193 G194 V199 A212 K214 M265 D269 L317 D328 D311 K313 E315 N316 D329 E338 T348 D310 K312 E314 N315 D328 E337 T347 2.7.11.16 0004672,0004674,0004703,0005515,0005524,0005737,0005886,0006468,0007165,0007186,0008277,0009966,0016020,0016055,0016310,0047696 P43250 20729810 577 ELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFS 3nyo B 2.92 BS01 AMP B 1 G195 V200 A213 K215 M266 D270 E315 L318 D329 G194 V199 A212 K214 M265 D269 E314 L317 D328 D311 K313 E315 N316 D329 E338 T348 D310 K312 E314 N315 D328 E337 T347 2.7.11.16 0004672,0004674,0004703,0005515,0005524,0005737,0005886,0006468,0007165,0007186,0008277,0009966,0016020,0016055,0016310,0047696 P43250 20729810 577 ELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFS 3nyq A 1.43 BS02 AMP A 1 S261 A262 A263 R283 Y284 G285 M286 T287 D368 K390 K395 S255 A256 A257 R277 Y278 G279 M280 T281 D357 K379 K384 T143 T163 H187 T287 E288 K390 K395 T137 T157 H181 T281 E282 K379 K384 ? 0000166,0003824 Q9L0A2 21338915 487 LFPALSPAPTGAPADRPALRFGERSLTYAELAAAAGATAGRIGRVAVWATPAMETGVAVVAALLAGVAAVPLNPKSGDKELAHILSDSAPSLVLAPPDAELPPALGALERVDVDVRARGAVPEDGADDGDPALVVYTSGTTGPPKGAVIPRRALATTLDALADAWQWTGEDVLVQGLPLFHVHGLVLGILGPLRRGGSVRHLGRFSTEGAARELNDGATMLFGVPTMYHRIAETLPADPELAKALAGARLLVSGSAALPVHDHERIAAATGRRVIERYGMTETLMNTSVRADGEPRAGTVGVPLPGVELRLVPIAALDGESVGEIQVRGPNLFTEYLNRPDATAAAFTEDGFFRTGDMAVRDPDGYVRIVGRKATDLIKSGGYKIGAGEIENALLEHPEVREAAVTGEPDPDLGERIVAWIVPADPAAPPALGTLADHVAARLAPHKRPRVVRYLDAVPR 3nyr A 1.45 BS02 AMP A 1 S261 A262 A263 R283 Y284 G285 M286 T287 D368 K390 K395 S255 A256 A257 R277 Y278 G279 M280 T281 D357 K379 K384 T143 T163 H187 T287 E288 K390 K395 T137 T157 H181 T281 E282 K379 K384 ? 0000166,0003824 Q9L0A2 21338915 487 LFPALSPAPTGAPADRPALRFGERSLTYAELAAAAGATAGRIGRVAVWATPAMETGVAVVAALLAGVAAVPLNPKSGDKELAHILSDSAPSLVLAPPDAELPPALGALERVDVDVRARGAVPEDGADDGDPALVVYTSGTTGPPKGAVIPRRALATTLDALADAWQWTGEDVLVQGLPLFHVHGLVLGILGPLRRGGSVRHLGRFSTEGAARELNDGATMLFGVPTMYHRIAETLPADPELAKALAGARLLVSGSAALPVHDHERIAAATGRRVIERYGMTETLMNTSVRADGEPRAGTVGVPLPGVELRLVPIAALDGESVGEIQVRGPNLFTEYLNRPDATAAAFTEDGFFRTGDMAVRDPDGYVRIVGRKATDLIKSGGYKIGAGEIENALLEHPEVREAAVTGEPDPDLGERIVAWIVPADPAAPPALGTLADHVAARLAPHKRPRVVRYLDAVPR 3nzt A 2.0 BS01 AMP A 1 I56 T57 K58 P59 N139 F140 S141 I289 Y307 I55 T56 K57 P58 N138 F139 S140 I286 Y304 6.3.2.2 0003824,0004357,0005524,0005829,0006750,0016874,0016879,0046872 Q5NHS8 502 YDFKKINNLRGIERETLRVTDCGNLATSNHPDGLGHKLTNNSITVDFSENLLELITKPHDSIDKAIGELYQLSAFTLDNMHSDEIILNTSMPLSANDNDIQEADFGSSNSGRMKRVYRKGLSARYGKIMQIISGIHYNFSFDKDLISNIATNKQVSISDIYFDVLNNYFEFMWLLPYLFGASPICAKTSVKNKPDYLSVLDDKFYVGEYATSLRMSDLGSPAQKDLAISYDNVKAYVKDLIQATDDTFADYKRIGLYNSQGQRIQLNDGILQIENEYYSAIRPKQIAKRGERPACALYNRGVEYVEVRVLDVDPFEPVGISKDTALFVEVMLMTCLDKDAKKYHKDIIKQAKQNLTAVAIQGRNPQLKLKKLDDDSEILLKDYALELFDEIEAVAKKMPKEYLDAVEIQKRKVLDISQTPSAKIIELARQHGYKKFILDISRRVSQQFRSYELPAAIVAKLKDQAGQSVAAEKELVANDKISLDEYINRYYKSSKGCC 3o0f A 1.94 BS01 AMP A 1 D24 R109 R112 G144 R145 P146 R161 S162 F165 K266 D18 R103 R106 G138 R139 P140 R155 S156 F159 K260 ? 0000166,0003824,0004534,0006259,0035312,0046872 A1A2L3 21538547 301 AEPPAQGWDIHCHTVFSDGTETPRTLVEQARKLGLHGVAIADHDTTAGWDEATEASEEIGLPLLLGTEITAVDEDVSVHMLAFQYDPSNEHISSMFANTRAARLRRTKRMVERLSQDFPITWDDVLAQVKEGERTTIGRPHIADALVAAGVYETRSDAFADAVSAKSKYYIPTPSPSTHEVIAAVKGAGGVVVAAHAGDPQRNRRLLSDEQLDAMIADGLDGLEVWHRGNPPEQRERLLTIAARHDLLVTGGSDWHGKGKPNGLGENLTDDDTVREILCRGVDLIGR 3o0m A 1.9 BS02 AMP A 1 D29 I30 L39 F92 Q93 T94 V95 H99 H101 D31 I32 L41 F94 Q95 T96 V97 H101 H103 N86 H97 H99 H101 N88 H99 H101 H103 ? 0000166,0003824,0006790,0009150,0046872,0047627 A0R291 25613812 155 GSMSCVFCAIVSGDAPAIRIYEDENFLGILDIRPFTRGHTLVIPKTHTVDLTDTPPETVAGMAAVGQRIARAARESGLHADGNNIAINDGKAAFQTVFHIHLHVVPRRNGDKLSFRRDPDREESGRLLRAALAQLDSAE 3o0m B 1.9 BS02 AMP B 1 F5 D29 I30 L39 F92 Q93 T94 V95 H99 H101 F4 D28 I29 L38 F91 Q92 T93 V94 H98 H100 N86 H97 H99 H101 N85 H96 H98 H100 ? 0000166,0003824,0006790,0009150,0046872,0047627 A0R291 25613812 155 SCVFCAIVSGDAPAIRIYEDENFLGILDIRPFTRGHTLVIPKTHTVDLTDTPPETVAGMAAVGQRIARAARESGLHADGNNIAINDGKAAFQTVFHIHLHVVPRRNGDKLSFRRDPDREESGRLLRAALAQLDSA 3ocv A 1.551 BS01 AMP A 1 D64 N66 F86 W91 T124 N125 R126 K161 Y221 D56 N58 F78 W83 T116 N117 R118 K153 Y213 3.1.3.2 0009279 P26093 20934434 263 EEHANMQLQQQAVLGLNWMQDSGEYKALAYQAYNAAKVAFDHAKVAKGKKKAVVADLNETMLDNSPYAGWQVQNNKPFDGKDWTRWVDARQSRAVPGAVEFNNYVNSHNGKVFYVTNRKDSTEKSGTIDDMKRLGFNGVEESAFYLKKDKSAKAARFAEIEKQGYEIVLYVGDNLDDFGNTVYGKLNADRRAFVDQNQGKFGKTFIMLPNANYGGWEGGLAEGYFKKDTQGQIKARLDAVQAWDGKL 3omf A 1.8 BS02 AMP A 1 F29 D31 I32 L41 N86 Q93 T94 H99 H101 F27 D29 I30 L39 N84 Q91 T92 H97 H99 N86 H97 H99 H101 N84 H95 H97 H99 3.9.1.- 0000166,0003824,0005634,0005737,0016787,0043530 C4LYI2 25945711 115 DSCIFCKIAQKQIPSTIVYEDDEIFAFKDINPIAPIHILVIPKQHIASLNEITEENEAFIGKVLYKVSLIGKKECPEGYRVVNNIGEDAGQTVKHIHFHILGGKKLAWDKL 3p4e A 1.77 BS01 AMP A 1 D108 I124 G140 G141 E142 T143 D85 I101 G117 G118 E119 T120 6.3.3.1 0004637,0004641,0005524,0005737,0005829,0006164,0006189,0016874,0046084 Q9KPY6 501 DAGNALVERIKGAVKRTRRPEVMGALCELPTKYKHPVLVSGTDGVGTKLRLALDMKKHDTIGIDLVAMCVNDLIVQGAEPLFFLDYYATGKLDVDTAAEVISGIADGCLQAGCALIGGETAEMPGMYEGEDYDVAGFCVGVVEKEEIIDGSKVQVGDALIAVGSSGPHSNGYSLVRKILEVSKADKNERLAGKTIGEHLLAPTKIYIKSGLKLIAEHDIHAISHITGGGFWENIPRVLPEGTKAVIDGKSWEWPVIFQWLQEKGNVTTHEMYRTFNCGVGLIIALPKDQANAAVALLQAEGETAWVIGEIAAANSNEAQVEIN 3pco A 3.02 BS02 AMP A 1 H202 T203 F206 E268 R301 L312 H117 T118 F121 E183 R216 L227 H155 Q169 R195 Q208 T251 A294 H70 Q84 R110 Q123 T166 A209 6.1.1.20 0000049,0000166,0000287,0004812,0004826,0005515,0005524,0005737,0005829,0006412,0006432,0009328,0043039,0046872 P08312 21082706 992 RLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDTTRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK 3pco C 3.02 BS02 AMP C 1 R195 T201 H202 F206 E268 R301 R191 T197 H198 F202 E264 R297 H155 Q169 R195 Q208 T251 A294 H151 Q165 R191 Q204 T247 A290 6.1.1.20 0000049,0000166,0000287,0004812,0004826,0005515,0005524,0005737,0005829,0006412,0006432,0009328,0043039,0046872 P08312 21082706 999 AELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDTTRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK 3py5 A 1.7 BS03 AMP A 1 S18 H88 A89 D90 H170 D188 H219 H241 S16 H86 A87 D88 H168 D186 H217 H239 ? 0000166,0046872 Q2YQ74 21904058 303 SPRNCLRFTLLGCGSSPGVPRINGDWGKCDPKNPKNRRRRASLLVERYDAEGNNTVVVIDTGPDFRMQMIDSGVHMLDAAVYTHPHADHIHGIDDLRTYVVDNGRLMDVYANRLTRNRLYDTFGYCFETPVGSSYPPILSMHDIAPETPFSIEGAGGAIRFEPFSQVHGDIESLGFRIGSVVYCTDVSAFPEQSLQYIKDADVLIIGALQYRPHPSHFSLGEALEWIEKLSPKRAILTHMHVPLDYETVMRETPHHVEPGYDGLRFEVAV 3q10 A 1.83 BS01 AMP A 1 P28 M30 H34 H37 L40 F148 G149 D152 T177 V178 L186 P29 M31 H35 H38 L41 F149 G150 D153 T178 V179 L187 M30 H34 H37 E77 D78 K81 K151 S187 S188 R189 M31 H35 H38 E78 D79 K82 K152 S188 S189 R190 6.3.2.1 0004592,0005524,0005737,0005829,0015940,0016874 Q8ZBK7 501 AMLIIETLPLLRQQIRRWRQEGKRIALVPTMGNLHEGHMTLVDEAKTRADVVVVTIFVNPLQFERPDDLAHYPRTLQEDCEKLTRHGADLVFAPAAADIYPAGLEKQTYVDVPALSTILEGASRPGHFRGVSTIVSKLFNLIQPDVACFGEKDYQQLALIRKMVADMGYDINIVGVPTVRAKDGLALSSRNGYLTEEERQIAPQLSKIMWALAEKMALGERQIDALLEEAAAQLLRVGFTPDELFIRDAETLQPLTVDSQQAVILMAAWLGKARLIDNQLVDLRH 3q10 B 1.83 BS01 AMP B 1 P28 H34 H37 L40 F148 G149 D152 T177 V178 L186 P29 H35 H38 L41 F149 G150 D153 T178 V179 L187 M30 H34 H37 E77 D78 K81 K151 M31 H35 H38 E78 D79 K82 K152 6.3.2.1 0004592,0005524,0005737,0005829,0015940,0016874 Q8ZBK7 501 AMLIIETLPLLRQQIRRWRQEGKRIALVPTMGNLHEGHMTLVDEAKTRADVVVVTIFVNPLQFERPDDLAHYPRTLQEDCEKLTRHGADLVFAPAAADIYPAGLEKQTYVDVPALSTILEGASRPGHFRGVSTIVSKLFNLIQPDVACFGEKDYQQLALIRKMVADMGYDINIVGVPTVRAKDGLALSSRNGYLTEEERQIAPQLSKIMWALAEKMALGERQIDALLEEAAAQLLRVGFTPDELFIRDAETLQPLTVDSQQAVILMAAWLGKARLIDNQLVDLRH 3q10 C 1.83 BS01 AMP C 1 H37 L40 G149 K151 T177 V178 L186 H39 L42 G151 K153 T179 V180 L188 M30 H34 H37 E77 D78 K81 K151 S187 S188 R189 M32 H36 H39 E79 D80 K83 K153 S189 S190 R191 6.3.2.1 0004592,0005524,0005737,0005829,0015940,0016874 Q8ZBK7 501 NAMLIIETLPLLRQQIRRWRQEGKRIALVPTMGNLHEGHMTLVDEAKTRADVVVVTIFVNPLQFERPDDLAHYPRTLQEDCEKLTRHGADLVFAPAAADIYPAGLEKQTYVDVPALSTILEGASRPGHFRGVSTIVSKLFNLIQPDVACFGEKDYQQLALIRKMVADMGYDINIVGVPTVRAKDGLALSSRNGYLTEEERQIAPQLSKIMWALAEKMALGERQIDALLEEAAAQLLRVGFTPDELFIRDAETLQPLTVDSQQAVILMAAWLGKARLIDNQLVDL 3q10 D 1.83 BS01 AMP D 1 P28 H37 L40 F148 G149 K151 T177 P29 H38 L41 F149 G150 K152 T178 M30 H34 H37 E77 D78 K81 K151 M31 H35 H38 E78 D79 K82 K152 6.3.2.1 0004592,0005524,0005737,0005829,0015940,0016874 Q8ZBK7 501 AMLIIETLPLLRQQIRRWRQEGKRIALVPTMGNLHEGHMTLVDEAKTRADVVVVTIFVNPLQFERPDDLAHYPRTLQEDCEKLTRHGADLVFAPAAADIYPAGLEKQTYVDVPALSTILEGASRPGHFRGVSTIVSKLFNLIQPDVACFGEKDYQQLALIRKMVADMGYDINIVGVPTPDELFIRVILMAAARLIDNQ 3qfo A 2.2 BS01 AMP A 1 H13 D39 N66 W67 R137 I140 H141 H164 H166 F189 H252 H11 D37 N64 W65 R135 I138 H139 H162 H164 F187 H250 ? 0000166,0005737,0016791,0046872 Q8DNX4 263 MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTGRRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEEIEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVYGHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRRVDYDVAAELQLAKDLRLPYFEVYYESLVNGIH 3qfo B 2.2 BS01 AMP B 1 H13 D39 N66 W67 R137 I140 H141 H164 H166 F189 H252 H11 D37 N64 W65 R135 I138 H139 H162 H164 F187 H250 ? 0000166,0005737,0016791,0046872 Q8DNX4 263 MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTGRRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEEIEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVYGHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRRVDYDVAAELQLAKDLRLPYFEVYYESLVNGIH 3qh8 A 1.6 BS03 AMP A 1 S18 H88 A89 D90 H170 D188 H219 H241 S18 H88 A89 D90 H170 D188 H219 H241 ? 0000166,0046872 Q2YQ74 21904058 303 MTSPRNCLRFTLLGCGSSPGVPRINGDWGKCDPKNPKNRRRRASLLVERYDAEGNNTVVVIDTGPDFRMQMIDSGVHMLDAAVYTHPHADHIHGIDDLRTYVVDNGRLMDVYANRLTRNRLYDTFGYCFETPVGSSYPPILSMHDIAPETPFSIEGAGGAIRFEPFSQVHGDIESLGFRIGSVVYCTDVSAFPEQSLQYIKDADVLIIGALQYRPHPSHFSLGEALEWIEKLSPKRAILTHMHVPLDYETVMRETPHHVEPGYDGLRFEVAV 3r96 A 1.3 BS02 AMP A 1 I35 M46 W48 F61 V88 S90 N92 G104 Y105 W106 I32 M43 W45 F58 V85 S87 N89 G101 Y102 W103 ? 0016747 Kd=1.03mM Q47510 21507941 500 DVSLTPSGIKVNDEITLLYPALKYAEELYLLINQNKINFIKSMAWPAFVNNISDSVSFIEQSMIDNQNEKALILFIKYKTKIAGVVSFNIIDHANKTAYIGYWLGANFQGKGIVTNAINKLIQEYGDSGVIKRFVIKCIVDNKKSNATALRCGFTLEGVLQKAEILNGVSYDQNIYSKVI 3r96 B 1.3 BS02 AMP B 1 M46 W48 F61 V88 S90 N92 G104 Y105 W106 M36 W38 F51 V78 S80 N82 G94 Y95 W96 ? 0016747 Kd=1.03mM Q47510 21507941 500 GIKVNDEITLLYPALKYAEELYLLINQNKINFIKSMAWPAFVNNISDSVSFIEQSMIDNQNEKALILFIKYKTKIAGVVSFNIIDHANKTAYIGYWLGANFQGKGIVTNAINKLIQEYGDSGVIKRFVIKCIVDNKKSNATALRCGFTLEGVLQKAEILNGVSYDQNIYSKVI 3rex A 1.8 BS01 AMP A 1 R99 H110 S111 F114 Q116 E215 V216 S217 G264 R267 R99 H110 S111 F114 Q116 E215 V216 S217 G264 R267 R99 E101 R109 H110 R99 E101 R109 H110 ? 0000166,0004812,0004816,0005524,0006412,0006418,0006421,0046872 Q9V228 21820443 295 MNAVEIISRDIYKAIDIQTKILDYMTKFFTDRGFKWLLPIMLSPITDPLWPDPAGEGIRPAEVDVYGVRMRLTHSMILHKQLAIAMGLEKIFVLSPNIRLESRRKDDGRHSYEFTQLDFEIEGAKMKDVMRLIEELIYGLFRKAEEWTGREFPRARHFKVYDYKDILEEFGSDEKASMEMEEPFWIVNIPREFYDREENGVWKNYDLILPYGYGEVSSGGEREWEYEKIVAKIRAAGLKEDSFRPYLEIARAGKLKPSAGAGIGVERLVRFIVGAKHIAEVQPFPRVPGIPAVI 3rex B 1.8 BS01 AMP B 1 R99 H110 S111 F114 Q116 E215 V216 S217 G264 R267 R95 H106 S107 F110 Q112 E211 V212 S213 G260 R263 R99 E101 R109 H110 R95 E97 R105 H106 ? 0000166,0004812,0004816,0005524,0006412,0006418,0006421,0046872 Q9V228 21820443 295 MNAVEIISRDIYKAIDIQTKILDYMTKFFTDRGFKWLLPIMLSPITDPLWPDPIRPAEVDVYGVRMRLTHSMILHKQLAIAMGLEKIFVLSPNIRLESRRKDDGRHSYEFTQLDFEIEGAKMKDVMRLIEELIYGLFRKAEEWTGREFPRARHFKVYDYKDILEEFGSDEKASMEMEEPFWIVNIPREFYDREENGVWKNYDLILPYGYGEVSSGGEREWEYEKIVAKIRAAGLKEDSFRPYLEIARAGKLKPSAGAGIGVERLVRFIVGAKHIAEVQPFPRVPGIPAVI 3rk0 A 2.4 BS01 AMP A 1 L10 S12 G14 D16 S17 A96 G97 Q104 R107 L7 S9 G11 D13 S14 A85 G86 Q93 R96 ? 0005524,0017178,0017183 Q8U2K6 22102225 301 LADVAVLYSGGKDSNYALYWAIKNRFSVKFLVTMVSENEMYHTINANLTDLQARALGIPLVKGFTKEVEDLKRVLSGLKIQGIVAGALASKYQRKRIEKVAKELGLEVYTPARDAKEYMRELLNLGFKIMVVGVSAYGLDESWLGRILDESALEELITLNEKYKVHVAGEGGEFETFVLDMPLFKYKIVVDKAKKVTSSGKLIIEEAHLESKLE 3rl6 A 2.0 BS02 AMP A 1 R99 H110 S111 F114 Q116 E215 V216 S217 G264 R267 R99 H110 S111 F114 Q116 E215 V216 S217 G264 R267 R99 E101 R109 H110 R99 E101 R109 H110 ? 0000166,0004812,0004816,0005524,0006412,0006418,0006421,0046872 Q9V228 21820443 296 MNAVEIISRDIYKAIDIQTKILDYMTKFFTDRGFKWLLPIMLSPITDPLWPDPAGEGIRPAEVDVYGVRMRLTHSMILHKQLAIAMGLEKIFVLSPNIRLESRRKDDGRHSYEFTQLDFEIEGAKMKDVMRLIEELIYGLFRKAEEWTGREFPRARHFKVYDYKDILEEFGSDEKASMEMEEPFWIVNIPREFYDREENGVWKNYDLILPYGYGEVSSGGEREWEYEKIVAKIRAAGLKEDSFRPYLEIARAGKLKPSAGAGIGVERLVRFIVGAKHIAEVQPFPRVPGIPAVI 3rl6 B 2.0 BS02 AMP B 1 R99 H110 S111 F114 E215 R267 R90 H101 S102 F105 E206 R258 R99 E101 R109 H110 R90 E92 R100 H101 ? 0000166,0004812,0004816,0005524,0006412,0006418,0006421,0046872 Q9V228 21820443 296 MNAVEIISRDIYKAIDIQTKILDYMTKFFTDRGFKWLLPIMLSPITDPLRPAEVDVYGVRMRLTHSMILHKQLAIAMGLEKIFVLSPNIRLESRRKDDGRHSYEFTQLDFEIEGAKMKDVMRLIEELIYGLFRKAEEWTGREFPRARHFKVYDYKDILEEFGSDEKASMEMEEPFWIVNIPREFYDREENGVWKNYDLILPYGYGEVSSGGEREWEYEKIVAKIRAAGLKEDSFRPYLEIARAGKLKPSAGAGIGVERLVRFIVGAKHIAEVQPFPRVPGIPAVI 3roj A 2.3 BS03 AMP A 1 R307 F309 R314 V341 I342 Q343 H345 R309 F311 R316 V343 I344 Q345 H347 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 348 GSVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3roj A 2.3 BS04 AMP B 1 R164 G211 N213 H215 R166 G213 N215 H217 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 348 GSVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3roj B 2.3 BS01 AMP A 1 R164 G211 N213 H215 R164 G211 N213 H215 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 348 VDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3roj B 2.3 BS02 AMP B 1 R307 F309 R314 V341 Q343 H345 R307 F309 R314 V341 Q343 H345 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 348 VDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3roj C 2.3 BS03 AMP C 1 R164 G211 N213 H215 R166 G213 N215 H217 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 348 GSVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3roj C 2.3 BS04 AMP C 2 R307 F309 R314 V341 Q343 H345 R309 F311 R316 V343 Q345 H347 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 349 GSVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3roj D 2.3 BS01 AMP C 1 R307 F309 R314 V341 I342 Q343 H345 R308 F310 R315 V342 I343 Q344 H346 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 348 SVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3roj D 2.3 BS02 AMP C 2 R164 G211 N213 H215 R165 G212 N214 H216 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 349 SVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3rph A 1.75 BS01 AMP A 1 K186 G187 N206 L209 A210 T214 G215 K187 G188 N207 L210 A211 T215 G216 4.2.1.136 0005524,0016829,0016836,0046496,0052855,0052856,0052857,0110051 P94368 22940582 278 AMNVPFWTEEHVRATLPERDAESHKGTYGTALLLAGSDDMPGAALLAGLGAMRSGLGKLVIGTSENVIPLIVPVLPEATYWRDGWKKAADAQLEETYRAIAIGPGLPQTESVQQAVDHVLTADCPVILDAGALAKRTYPKREGPVILTPHPGEFFRMTGVPVNELQKKRAEYAKEWAAQLQTVIVLKGNQTVIAFPDGDCWLNPTGNGALAKGGTGDTLTGMILGMLCCHEDPKHAVLNAVYLHGACAELWTDEHSAHTLLAHELSDILPRVWKRFE 3rph A 1.75 BS02 AMP A 2 H149 P150 H150 P151 4.2.1.136 0005524,0016829,0016836,0046496,0052855,0052856,0052857,0110051 P94368 22940582 280 AMNVPFWTEEHVRATLPERDAESHKGTYGTALLLAGSDDMPGAALLAGLGAMRSGLGKLVIGTSENVIPLIVPVLPEATYWRDGWKKAADAQLEETYRAIAIGPGLPQTESVQQAVDHVLTADCPVILDAGALAKRTYPKREGPVILTPHPGEFFRMTGVPVNELQKKRAEYAKEWAAQLQTVIVLKGNQTVIAFPDGDCWLNPTGNGALAKGGTGDTLTGMILGMLCCHEDPKHAVLNAVYLHGACAELWTDEHSAHTLLAHELSDILPRVWKRFE 3rpl A 2.4 BS04 AMP A 1 R307 F309 R314 V341 Q343 H345 R309 F311 R316 V343 Q345 H347 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 349 GSVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3rpl A 2.4 BS05 AMP B 1 R164 G211 N213 H215 R166 G213 N215 H217 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 349 GSVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3rpl B 2.4 BS01 AMP A 1 R164 G211 N213 H215 R168 G215 N217 H219 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 349 GRGSVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3rpl B 2.4 BS02 AMP B 1 R307 F309 R314 V341 Q343 H345 R311 F313 R318 V345 Q347 H349 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 349 GRGSVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3rpl C 2.4 BS04 AMP C 1 R307 F309 R314 Q343 H345 R309 F311 R316 Q345 H347 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 349 GSVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3rpl C 2.4 BS05 AMP D 1 R164 G211 N213 H215 R166 G213 N215 H217 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 349 GSVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3rpl D 2.4 BS01 AMP C 1 R164 G211 N213 H215 R165 G212 N214 H216 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 349 SVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3rpl D 2.4 BS02 AMP D 1 R307 F309 R314 V341 Q343 H345 R308 F310 R315 V342 Q344 H346 3.1.3.11,3.1.3.37 0006071,0006094,0016787,0019253,0030388,0042132,0046872,0050278 P73922 349 SVDSTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIHMRGRIVIGEGERDDAPMLYIGEEVGICTREDAKSFCNPDELVEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGHVDIDKSATENLKILSDCLNRSIEELVVVVMDRPRHKELIQEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESREGNLERLASMGIKNPDQVYNCEELACGETVLFAACGITPGTLMEGVRFFHGGVRTQSLVISSQSSTARFVDTVHMKESPKVIQLH 3rpz A 1.51 BS01 AMP A 1 K186 G187 N206 L209 A210 T214 G215 K187 G188 N207 L210 A211 T215 G216 4.2.1.136 0005524,0016829,0016836,0046496,0052855,0052856,0052857,0110051 P94368 22940582 278 AMNVPFWTEEHVRATLPERDAESHKGTYGTALLLAGSDDMPGAALLAGLGAMRSGLGKLVIGTSENVIPLIVPVLPEATYWRDGWKKAADAQLEETYRAIAIGPGLPQTESVQQAVDHVLTADCPVILDAGALAKRTYPKREGPVILTPHPGEFFRMTGVPVNELQKKRAEYAKEWAAQLQTVIVLKGNQTVIAFPDGDCWLNPTGNGALAKGGTGDTLTGMILGMLCCHEDPKHAVLNAVYLHGACAELWTDEHSAHTLLAHELSDILPRVWKRFE 3rq2 A 1.8 BS01 AMP A 1 K186 G187 N206 L209 A210 T214 G215 K187 G188 N207 L210 A211 T215 G216 4.2.1.136 0005524,0016829,0016836,0046496,0052855,0052856,0052857,0110051 P94368 22940582 278 AMNVPFWTEEHVRATLPERDAESHKGTYGTALLLAGSDDMPGAALLAGLGAMRSGLGKLVIGTSENVIPLIVPVLPEATYWRDGWKKAADAQLEETYRAIAIGPGLPQTESVQQAVDHVLTADCPVILDAGALAKRTYPKREGPVILTPHPGEFFRMTGVPVNELQKKRAEYAKEWAAQLQTVIVLKGNQTVIAFPDGDCWLNPTGNGALAKGGTGDTLTGMILGMLCCHEDPKHAVLNAVYLHGACAELWTDEHSAHTLLAHELSDILPRVWKRFE 3rrb A 2.4 BS02 AMP A 1 H366 K402 S403 A404 N421 L424 S425 S429 G430 H366 K402 S403 A404 N421 L424 S425 S429 G430 4.2.1.136,5.1.99.6 0005524,0016829,0016836,0016853,0046496,0046872,0052855,0052856,0052857,0110051 Q9X024 22940582 492 MKEIDELTIKEYGVDSRILMERAGISVVLAMEEELGNLSDYRFLVLCGGGNNGGDGFVVARNLLGVVKDVLVVFLGKKKTPDCEYNYGLYKKFGGKVVEQFEPSILNEFDVVVDAIFGTGLRGEITGEYAEIINLVNKSGKVVVSVDVPSGIDSNTGKVLRTAVKADLTVTFGVPKIGHILFPGRDLTGKLKVANIGHPVHLINSINRYVITREMVRSLLPERPRDSHKGTYGKVLIIAGSRLYSGAPVLSGMGSLKVGTGLVKLAVPFPQNLIATSRFPELISVPIDTEKGFFSLQNLQECLELSKDVDVVAIGPGLGNNEHVREFVNEFLKTLEKPAVIDADAINVLDTSVLKERKSPAVLTPHPGEMARLVKKTVGDVKYNYELAEEFAKENDCVLVLKSATTIVTDGEKTLFNITGNTGLSKGGSGDVLTGMIAGFIAQGLSPLEASTVSVYLHGFAAELFEQDERGLTASELLRLIPEAIRRLK 3rrb A 2.4 BS03 AMP A 2 H366 P367 V378 K382 H366 P367 V378 K382 4.2.1.136,5.1.99.6 0005524,0016829,0016836,0016853,0046496,0046872,0052855,0052856,0052857,0110051 Q9X024 22940582 493 MKEIDELTIKEYGVDSRILMERAGISVVLAMEEELGNLSDYRFLVLCGGGNNGGDGFVVARNLLGVVKDVLVVFLGKKKTPDCEYNYGLYKKFGGKVVEQFEPSILNEFDVVVDAIFGTGLRGEITGEYAEIINLVNKSGKVVVSVDVPSGIDSNTGKVLRTAVKADLTVTFGVPKIGHILFPGRDLTGKLKVANIGHPVHLINSINRYVITREMVRSLLPERPRDSHKGTYGKVLIIAGSRLYSGAPVLSGMGSLKVGTGLVKLAVPFPQNLIATSRFPELISVPIDTEKGFFSLQNLQECLELSKDVDVVAIGPGLGNNEHVREFVNEFLKTLEKPAVIDADAINVLDTSVLKERKSPAVLTPHPGEMARLVKKTVGDVKYNYELAEEFAKENDCVLVLKSATTIVTDGEKTLFNITGNTGLSKGGSGDVLTGMIAGFIAQGLSPLEASTVSVYLHGFAAELFEQDERGLTASELLRLIPEAIRRLK 3sbx A 2.5 BS01 AMP A 1 E80 M95 R98 K99 G115 G117 T118 D120 E121 E71 M86 R89 K90 G106 G108 T109 D111 E112 3.2.2.n1 0000166,0005829,0009691,0016787,0016799,0102682 B2HS63 25613812 188 RWTVAVYCAAAPTHPELLELAGAVGAAIAARGWTLVWGGGHVSAMGAVSSAARAHGGWTVGVIPKMLVHRELADHDADELVVTETMWERKQVMEDRANAFITLPGGVGTLDELLDVWTEGYLGMHDKSIVVLDPWGHFDGLRAWLSELADTGYVSRTAMERLIVVDNLDDALQACAP 3sbx B 2.5 BS01 AMP B 1 A19 M54 E80 M95 R98 K99 G115 G117 T118 D120 E121 A10 M45 E71 M86 R89 K90 G106 G108 T109 D111 E112 3.2.2.n1 0000166,0005829,0009691,0016787,0016799,0102682 B2HS63 25613812 188 RWTVAVYCAAAPTHPELLELAGAVGAAIAARGWTLVWGGGHVSAMGAVSSAARAHGGWTVGVIPKMLVHRELADHDADELVVTETMWERKQVMEDRANAFITLPGGVGTLDELLDVWTEGYLGMHDKSIVVLDPWGHFDGLRAWLSELADTGYVSRTAMERLIVVDNLDDALQACAP 3sbx C 2.5 BS01 AMP C 1 A18 A19 M54 E80 M95 R98 K99 G115 G117 T118 E121 A9 A10 M45 E71 M86 R89 K90 G106 G108 T109 E112 3.2.2.n1 0000166,0005829,0009691,0016787,0016799,0102682 B2HS63 25613812 188 RWTVAVYCAAAPTHPELLELAGAVGAAIAARGWTLVWGGGHVSAMGAVSSAARAHGGWTVGVIPKMLVHRELADHDADELVVTETMWERKQVMEDRANAFITLPGGVGTLDELLDVWTEGYLGMHDKSIVVLDPWGHFDGLRAWLSELADTGYVSRTAMERLIVVDNLDDALQACAP 3sbx D 2.5 BS01 AMP D 1 A19 M54 E80 M95 R98 K99 G115 G117 T118 D120 E121 A10 M45 E71 M86 R89 K90 G106 G108 T109 D111 E112 3.2.2.n1 0000166,0005829,0009691,0016787,0016799,0102682 B2HS63 25613812 188 RWTVAVYCAAAPTHPELLELAGAVGAAIAARGWTLVWGGGHVSAMGAVSSAARAHGGWTVGVIPKMLVHRELADHDADELVVTETMWERKQVMEDRANAFITLPGGVGTLDELLDVWTEGYLGMHDKSIVVLDPWGHFDGLRAWLSELADTGYVSRTAMERLIVVDNLDDALQACAP 3sbx E 2.5 BS01 AMP E 1 A18 A19 M54 E80 M95 R98 K99 G115 G117 T118 E121 A9 A10 M45 E71 M86 R89 K90 G106 G108 T109 E112 3.2.2.n1 0000166,0005829,0009691,0016787,0016799,0102682 B2HS63 25613812 188 RWTVAVYCAAAPTHPELLELAGAVGAAIAARGWTLVWGGGHVSAMGAVSSAARAHGGWTVGVIPKMLVHRELADHDADELVVTETMWERKQVMEDRANAFITLPGGVGTLDELLDVWTEGYLGMHDKSIVVLDPWGHFDGLRAWLSELADTGYVSRTAMERLIVVDNLDDALQACAP 3sbx F 2.5 BS01 AMP E 1 T127 L131 T118 L122 3.2.2.n1 0000166,0005829,0009691,0016787,0016799,0102682 B2HS63 25613812 188 RWTVAVYCAAAPTHPELLELAGAVGAAIAARGWTLVWGGGHVSAMGAVSSAARAHGGWTVGVIPKMLVHRELADHDADELVVTETMWERKQVMEDRANAFITLPGGVGTLDELLDVWTEGYLGMHDKSIVVLDPWGHFDGLRAWLSELADTGYVSRTAMERLIVVDNLDDALQACAP 3sbx F 2.5 BS02 AMP F 1 A19 E80 M95 R98 K99 G115 G117 T118 D120 E121 A10 E71 M86 R89 K90 G106 G108 T109 D111 E112 3.2.2.n1 0000166,0005829,0009691,0016787,0016799,0102682 B2HS63 25613812 188 RWTVAVYCAAAPTHPELLELAGAVGAAIAARGWTLVWGGGHVSAMGAVSSAARAHGGWTVGVIPKMLVHRELADHDADELVVTETMWERKQVMEDRANAFITLPGGVGTLDELLDVWTEGYLGMHDKSIVVLDPWGHFDGLRAWLSELADTGYVSRTAMERLIVVDNLDDALQACAP 3sbx G 2.5 BS01 AMP G 1 A19 E80 M95 R98 K99 G115 G117 T118 D120 E121 A10 E71 M86 R89 K90 G106 G108 T109 D111 E112 3.2.2.n1 0000166,0005829,0009691,0016787,0016799,0102682 B2HS63 25613812 188 RWTVAVYCAAAPTHPELLELAGAVGAAIAARGWTLVWGGGHVSAMGAVSSAARAHGGWTVGVIPKMLVHRELADHDADELVVTETMWERKQVMEDRANAFITLPGGVGTLDELLDVWTEGYLGMHDKSIVVLDPWGHFDGLRAWLSELADTGYVSRTAMERLIVVDNLDDALQACAP 3sbx H 2.5 BS01 AMP H 1 A18 A19 M54 E80 M95 R98 K99 G115 G117 T118 D120 E121 A9 A10 M45 E71 M86 R89 K90 G106 G108 T109 D111 E112 3.2.2.n1 0000166,0005829,0009691,0016787,0016799,0102682 B2HS63 25613812 188 RWTVAVYCAAAPTHPELLELAGAVGAAIAARGWTLVWGGGHVSAMGAVSSAARAHGGWTVGVIPKMLVHRELADHDADELVVTETMWERKQVMEDRANAFITLPGGVGTLDELLDVWTEGYLGMHDKSIVVLDPWGHFDGLRAWLSELADTGYVSRTAMERLIVVDNLDDALQACAP 3sf0 A 1.35 BS02 AMP A 1 N64 D66 F86 W91 N125 R126 K161 Y221 N56 D58 F78 W83 N117 R118 K153 Y213 3.1.3.2 0009279 P26093 21933344 264 EEHANMQLQQQAVLGLNWMQDSGEYKALAYQAYNAAKVAFDHAKVAKGKKKAVVANLDETMLDNSPYAGWQVQNNKPFDGKDWTRWVDARQSRAVPGAVEFNNYVNSHNGKVFYVTNRKDSTEKSGTIDDMKRLGFNGVEESAFYLKKDKSAKAARFAEIEKQGYEIVLYVGDNLDDFGNTVYGKLNADRRAFVDQNQGKFGKTFIMLPNANYGGWEGGLAEGYFKKDTQGQIKARLDAVQAWDGKL 3sgi A 3.5 BS01 AMP A 1 L92 K123 E184 H236 V298 L85 K116 E177 H229 V291 E121 K123 D125 H236 K324 E114 K116 D118 H229 K317 6.5.1.2 0003911,0006260,0006281 P9WNV1 616 QTAPEVLRQWQALAEEVREHQFRYYVRDAPIISDAEFDELLRRLEALEEQHPELRTPDSPTQLVGGAGFATDFEPVDHLERMLSLDNAFTADELAAWAGRIHAEVGDAAHYLCELKIDGVALSLVYREGRLTRASTRGDGRTGEDVTLNARTIADVPERLTPGDDYPVPEVLEVRGEVFFRLDDFQALNASLVEEGKAPFANPRNSAAGSLRQKDPAVTARRRLRMICHGLGHVEGFRPATLHQAYLALRAWGLPVSEHTTLATDLAGVRERIDYWGEHRHEVDHEIDGVVVKVDEVALQRRLGSTSRAPRWAIAYKYPPEEAQTKLLDIRVNVGRTGRITPFAFMTPVKVAGSTVGQATLHNASEIKRKGVLIGDTVVIRKAGDVIPEVLGPVVELRDGSEREFIMP 3sp1 A 2.55 BS02 AMP A 1 T30 G38 N39 T42 Y43 G239 H242 F271 L272 T30 G38 N39 T42 Y43 G198 H201 F230 L231 6.1.1.16 0000166,0004812,0004817,0005524,0005737,0006412,0006418,0006423,0008270,0046872 O51545 28303005 482 MILKLYNTRTKDFSELTNFENVKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKVNYAMNITDIGHLLTVYEISEFFTEAFFNDCRKLNIVYPDKVLVASKHIPIMIEVVKILEEKKITYFSNGNVYFDTSCFKSYGEMAGFKRNKTDFVLWFTNSKMKWDSPWGFGYPSWHLECAAMNLEYFKDALDIHLGGVDHIGVHHINEIAIAECFLNKKWCDVFVHGEFLIMDFITVKDLEDQNFSPLDFRYLCLTSHYRNQLKFSLDNLQASKIARENLINKLSYFYESLDPVDLNTLNKDLKNFGFSVEKEYYDSFVEKISFDLNVAQGLALLWEIIKSDNLSFVSKLRLAFIFDEIMSLNLREEILKNLQNHDVVIDENMKALIEERRIAKCEKNFKRADEIRDFFAKKGFVLV 3sp1 B 2.55 BS02 AMP B 1 G38 N39 T42 Y43 G239 H242 F271 L272 K278 M279 G39 N40 T43 Y44 G206 H209 F238 L239 K245 M246 6.1.1.16 0000166,0004812,0004817,0005524,0005737,0006412,0006418,0006423,0008270,0046872 O51545 28303005 482 SMILKLYNTRTKDFSELTNFENVKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKVNYAMNITDIGHGLTVYEISEFFTEAFFNDCRKLNIVYPDKVLVASKHIPIMIEVVKILEEKKITYFSNGNVYFDTSCFKSYGEMAGIKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKDALDIHLGGVDHIGVHHINEIAIAECFLNKKWCDVFVHGEFLIMDYNKMSFITVKDLEDQNFSPLDFRYLCLTSHYRNQLKFSLDNLQASKIARENLINKLSYFYESLDPVDLNTLNKDLKNFGFSVEKEYYDSFVEKISFDLNVAQGLALLWEIIKSDNLSFVSKLRLAFIFDEIMSLNLREEILKNLQNHDVVIDENMKALIEERRIAKCEKNFKRADEIRDFFAKKGFVLVDGTKVKRG 3spl A 2.101 BS04 AMP A 1 L38 Y41 D63 M64 F65 H138 P141 S142 M143 H147 H149 L6 Y9 D31 M32 F33 H106 P109 S110 M111 H115 H117 3.6.1.71,3.6.1.72 0003824 O74859 21984208 800 SFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLTHVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALANYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTSNLPTRGTLTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSVSM 3spl B 2.101 BS04 AMP B 1 L38 Y41 D63 M64 F65 H138 P141 S142 M143 H147 H149 L6 Y9 D31 M32 F33 H106 P109 S110 M111 H115 H117 3.6.1.71,3.6.1.72 0003824 O74859 21984208 800 SFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLTHVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALANYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTSNLPTRGTLTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSVSM 3spl C 2.101 BS04 AMP C 1 L38 Y41 D63 M64 F65 H138 P141 S142 M143 H147 H149 L6 Y9 D31 M32 F33 H106 P109 S110 M111 H115 H117 3.6.1.71,3.6.1.72 0003824 O74859 21984208 800 SFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLTHVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALANYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTSNLPTRGTLTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSVSM 3spl D 2.101 BS04 AMP D 1 L38 Y41 D63 M64 F65 H138 P141 S142 M143 H147 H149 L6 Y9 D31 M32 F33 H106 P109 S110 M111 H115 H117 3.6.1.71,3.6.1.72 0003824 O74859 21984208 800 SFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLTHVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALANYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTSNLPTRGTLTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSVSM 3sr0 A 1.565 BS02 AMP A 1 T31 G32 L35 R36 M53 E57 V59 I64 G82 R85 Q89 R150 R161 T31 G32 L35 R36 M53 E57 V59 I64 G82 R85 Q89 R150 R161 K13 R85 R124 R150 R161 K13 R85 R124 R150 R161 2.7.4.3 0004017,0004550,0005524,0005737,0005829,0006139,0009123,0009132,0009165,0016301,0016310,0016776,0019205,0043231,0044209,0046940,0050145 O66490 25580578 208 MILVFLGPPGAGKGTQAKRLAKEKGFVHISTGDILREAVQKGTPLGKKAKEYMERGELVPDDLIIALIEEVFPKHGNVIFDGFPRTVKQAEALDEMLEKKGLKVDHVLLFEVPDEVVIERLSGRRINPETGEVYHVKYNPPPPGVKVIQREDDKPEVIKKRLEVYREQTAPLIEYYKKKGILRIIDASKPVEEVYRQVLEVIG 3sr0 B 1.565 BS02 AMP B 1 T31 L35 R36 M53 E57 L58 V59 I64 G82 R85 Q89 R150 T31 L35 R36 M53 E57 L58 V59 I64 G82 R85 Q89 R150 K13 R85 R124 R150 R161 K13 R85 R124 R150 R161 2.7.4.3 0004017,0004550,0005524,0005737,0005829,0006139,0009123,0009132,0009165,0016301,0016310,0016776,0019205,0043231,0044209,0046940,0050145 O66490 25580578 208 MILVFLGPPGAGKGTQAKRLAKEKGFVHISTGDILREAVQKGTPLGKKAKEYMERGELVPDDLIIALIEEVFPKHGNVIFDGFPRTVKQAEALDEMLEKKGLKVDHVLLFEVPDEVVIERLSGRRINPETGEVYHVKYNPPPPGVKVIQREDDKPEVIKKRLEVYREQTAPLIEYYKKKGILRIIDASKPVEEVYRQVLEVIG 3syt A 2.6511 BS03 AMP A 1 G366 V367 S368 S373 L399 R462 T480 G366 V367 S368 S373 L399 R456 T474 6.3.5.1 0003952,0004359,0005524,0005737,0005886,0008795,0009274,0009435,0016874,0042802 P9WJJ3 22280445 681 MNFYSAYQHGFVRVAACTHHTTIGDPAANAASVLDMARACHDDGAALAVFPELTLSGYSIEDVLLQDSLLDAVEDALLDLVTESADLLPVLVVGAPLRHRHRIYNTAVVIHRGAVLGVVPKSYLPTYREFYERRQMAPGDGERGTIRIGGADVAFGTDLLFAASDLPGFVLHVEICEDMFVPMPPSAEAALAGATVLANLSGSPITIGRAEDRRLLARSASARCLAAYVYAAAGEGESTTDLAWDGQTMIWENGALLAESERFPKGVRRSVADVDTELLRSERLRMGTFDDNRRHHRELTESFRRIDFALDPPAGDIGLLREVERFPFVPADPQRLQQDCYEAYNIQVSGLEQRLRALDYPKVVIGVSGGLDSTHALIVATHAMDREGRPRSDILAFALPGFKNNAIKLARALGVTFSEIDIGDTARLMLHTIGHPYSVGEKVYDVTFENVQAGLRTDYLFRIANQRGGIVLGTGDLSELALGWSTYGVGDQMSHYNVNAGVPKTLIQHLIRWVISAGEFGEKVGEVLQSVLDTEITSEAKVGPFALQDFSLFQVLRYGFRPSKIAFLAWHAWNDAERGNWPPGFPKSERPSYSLAEIRHWLQIFVQRFYSFSQFKRSALPNGPKVSHGGALSPRGDWRAPSDMSARIWLDQIDREVPKG 3syt B 2.6511 BS03 AMP B 1 G366 V367 S368 L399 R462 T480 G366 V367 S368 L399 R456 T474 6.3.5.1 0003952,0004359,0005524,0005737,0005886,0008795,0009274,0009435,0016874,0042802 P9WJJ3 22280445 681 MNFYSAYQHGFVRVAACTHHTTIGDPAANAASVLDMARACHDDGAALAVFPELTLSGYSIEDVLLQDSLLDAVEDALLDLVTESADLLPVLVVGAPLRHRHRIYNTAVVIHRGAVLGVVPKSYLPTYREFYERRQMAPGDGERGTIRIGGADVAFGTDLLFAASDLPGFVLHVEICEDMFVPMPPSAEAALAGATVLANLSGSPITIGRAEDRRLLARSASARCLAAYVYAAAGEGESTTDLAWDGQTMIWENGALLAESERFPKGVRRSVADVDTELLRSERLRMGTFDDNRRHHRELTESFRRIDFALDPPAGDIGLLREVERFPFVPADPQRLQQDCYEAYNIQVSGLEQRLRALDYPKVVIGVSGGLDSTHALIVATHAMDREGRPRSDILAFALPGFKNNAIKLARALGVTFSEIDIGDTARLMLHTIGHPYSVGEKVYDVTFENVQAGLRTDYLFRIANQRGGIVLGTGDLSELALGWSTYGVGDQMSHYNVNAGVPKTLIQHLIRWVISAGEFGEKVGEVLQSVLDTEITSEAKVGPFALQDFSLFQVLRYGFRPSKIAFLAWHAWNDAERGNWPPGFPKSERPSYSLAEIRHWLQIFVQRFYSFSQFKRSALPNGPKVSHGGALSPRGDWRAPSDMSARIWLDQIDREVPKG 3syt C 2.6511 BS04 AMP C 1 G366 V367 S368 A398 L399 R462 T480 G366 V367 S368 A398 L399 R448 T466 6.3.5.1 0003952,0004359,0005524,0005737,0005886,0008795,0009274,0009435,0016874,0042802 P9WJJ3 22280445 681 MNFYSAYQHGFVRVAACTHHTTIGDPAANAASVLDMARACHDDGAALAVFPELTLSGYSIEDVLLQDSLLDAVEDALLDLVTESADLLPVLVVGAPLRHRHRIYNTAVVIHRGAVLGVVPKSYLPTYREFYERRQMAPGDGERGTIRIGGADVAFGTDLLFAASDLPGFVLHVEICEDMFVPMPPSAEAALAGATVLANLSGSPITIGRAEDRRLLARSASARCLAAYVYAAAGEGESTTDLAWDGQTMIWENGALLAESERFPKGVRRSVADVDTELLRSERLRMGTFDDNRRHHRELTESFRRIDFALDPPAGDIGLLREVERFPFVPADPQRLQQDCYEAYNIQVSGLEQRLRALDYPKVVIGVSGGLDSTHALIVATHAMDREGRPRSDILAFALPGFKNNAIKLARALGVTFSEIDIGDTARLMLHTIGHPDVTFENVQAGLRTDYLFRIANQRGGIVLGTGDLSELALGWSTYGVGDQMSHYNVNAGVPKTLIQHLIRWVISAGEFGEKVGEVLQSVLDTEISEAKVGPFALQDFSLFQVLRYGFRPSKIAFLAWHAWNDAERGNWPPGFPKSERPSYSLAEIRHWLQIFVQRFYSFSQFKRSALPNGPKVSHGGALSPRGDWRAPSDMSARIWLDQIDREVPKG 3syt D 2.6511 BS04 AMP D 1 G366 V367 S368 A398 L399 R462 G366 V367 S368 A398 L399 R446 6.3.5.1 0003952,0004359,0005524,0005737,0005886,0008795,0009274,0009435,0016874,0042802 P9WJJ3 22280445 681 MNFYSAYQHGFVRVAACTHHTTIGDPAANAASVLDMARACHDDGAALAVFPELTLSGYSIEDVLLQDSLLDAVEDALLDLVTESADLLPVLVVGAPLRHRHRIYNTAVVIHRGAVLGVVPKSYLPTYREFYERRQMAPGDGERGTIRIGGADVAFGTDLLFAASDLPGFVLHVEICEDMFVPMPPSAEAALAGATVLANLSGSPITIGRAEDRRLLARSASARCLAAYVYAAAGEGESTTDLAWDGQTMIWENGALLAESERFPKGVRRSVADVDTELLRSERLRMGTFDDNRRHHRELTESFRRIDFALDPPAGDIGLLREVERFPFVPADPQRLQQDCYEAYNIQVSGLEQRLRALDYPKVVIGVSGGLDSTHALIVATHAMDREGRPRSDILAFALPGFKNNAIKLARALGVTFSEIDIGDTARLMLHTIGHVTFENVQAGLRTDYLFRIANQRGGIVLGTGDLSELALGWSTYGVGDQMSHYNVNAGVPKTLIQHLIRWVISAGEFGEKVGEVLQSVLDTEISEAKVGPFALQDFSLFQVLRYGFRPSKIAFLAWHAWNDAERGNWPPGFPKSERPSYSLAEIRHWLQIFVQRFYSFSQFKRSALPNGPKVSHGGALSPRGDWRAPSDMSARIWLDQIDREVPKG 3szg A 2.25 BS02 AMP A 1 G366 V367 S368 S373 A398 L399 T480 G366 V367 S368 S373 A398 L399 T465 6.3.5.1 0003952,0004359,0005524,0005737,0005886,0008795,0009274,0009435,0016874,0042802 P9WJJ3 22280445 681 MNFYSAYQHGFVRVAACTHHTTIGDPAANAASVLDMARACHDDGAALAVFPELTLSGYSIEDVLLQDSLLDAVEDALLDLVTESADLLPVLVVGAPLRHRHRIYNTAVVIHRGAVLGVVPKSYLPTYREFYERRQMAPGDGERGTIRIGGADVAFGTDLLFAASDLPGFVLHVEIAEDMFVPMPPSAEAALAGATVLANLSGSPITIGRAEDRRLLARSASARCLAAYVYAAAGEGESTTDLAWDGQTMIWENGALLAESERFPKGVRRSVADVDTELLRSERLRMGTFDDNRRHHRELTESFRRIDFALDPPAGDIGLLREVERFPFVPADPQRLQQDCYEAYNIQVSGLEQRLRALDYPKVVIGVSGGLDSTHALIVATHAMDREGRPRSDILAFALPGFKNNAIKLARALGVTFSEIDIGDTARLMLHTIGHDVTFENVQAGLRTDYLFRIANQRGGIVLGTGDLSELALGWSTYGVGDQMSHYNVNAGVPKTLIQHLIRWVISAGEFGEKVGEVLQSVLDTEISEAKVGPFALQDFSLFQVLRYGFRPSKIAFLAWHAWNDAERGNWPPGFPKSERPSYSLAEIRHWLQIFVQRFYSFSQFKRSALPNGPKVSHGGALSPRGDWRAPSDMSARIWLDQIDREVPKG 3szg B 2.25 BS02 AMP B 1 G366 S368 A398 L399 R462 G366 S368 A398 L399 R446 6.3.5.1 0003952,0004359,0005524,0005737,0005886,0008795,0009274,0009435,0016874,0042802 P9WJJ3 22280445 681 MNFYSAYQHGFVRVAACTHHTTIGDPAANAASVLDMARACHDDGAALAVFPELTLSGYSIEDVLLQDSLLDAVEDALLDLVTESADLLPVLVVGAPLRHRHRIYNTAVVIHRGAVLGVVPKSYLPTYREFYERRQMAPGDGERGTIRIGGADVAFGTDLLFAASDLPGFVLHVEIAEDMFVPMPPSAEAALAGATVLANLSGSPITIGRAEDRRLLARSASARCLAAYVYAAAGEGESTTDLAWDGQTMIWENGALLAESERFPKGVRRSVADVDTELLRSERLRMGTFDDNRRHHRELTESFRRIDFALDPPAGDIGLLREVERFPFVPADPQRLQQDCYEAYNIQVSGLEQRLRALDYPKVVIGVSGGLDSTHALIVATHAMDREGRPRSDILAFALPGKNNAIKLARALGVTFSEIDIGDTARLMLHTIGHDVTFENVQAGLRTDYLFRIANQRGGIVLGTGDLSELALGWSTYGVGDQMSHYNVNAGVPKTLIQHLIRWVISAGEFGEKVGEVLQSVLDTEITEAKVGPFALQDFSLFQVLRYGFRPSKIAFLAWHAWNDAERGNWPPGFPKSERPSYSLAEIRHWLQIFVQRFYSFSQFKRSALPNGPKVSHGGALSPRGDWRAPSDMSARIWLDQIDREVPKG 3szg C 2.25 BS03 AMP C 1 G366 V367 S368 L399 R462 T480 G367 V368 S369 L400 R457 T475 6.3.5.1 0003952,0004359,0005524,0005737,0005886,0008795,0009274,0009435,0016874,0042802 P9WJJ3 22280445 681 SMNFYSAYQHGFVRVAACTHHTTIGDPAANAASVLDMARACHDDGAALAVFPELTLSGYSIEDVLLQDSLLDAVEDALLDLVTESADLLPVLVVGAPLRHRHRIYNTAVVIHRGAVLGVVPKSYLPTYREFYERRQMAPGDGERGTIRIGGADVAFGTDLLFAASDLPGFVLHVEIAEDMFVPMPPSAEAALAGATVLANLSGSPITIGRAEDRRLLARSASARCLAAYVYAAAGEGESTTDLAWDGQTMIWENGALLAESERFPKGVRRSVADVDTELLRSERLRMGTFDDNRRHHRELTESFRRIDFALDPPAGDIGLLREVERFPFVPADPQRLQQDCYEAYNIQVSGLEQRLRALDYPKVVIGVSGGLDSTHALIVATHAMDREGRPRSDILAFALPGFKNNAIKLARALGVTFSEIDIGDTARLMLHTIGHPYSVGEKVYDVTFENVQAGLRTDYLFRIANQRGGIVLGTGDLSELALGWSTYGVGDQMSHYNVNAGVPKTLIQHLIRWVISAGEFGEKVGEVLQSVLDTEISEAKVGPFALQDFSLFQVLRYGFRPSKIAFLAWHAWNDAERGNWPPGFPKSERPSYSLAEIRHWLQIFVQRFYSFSQFKRSALPNGPKVSHGGALSPRGDWRAPSDMSARIWLDQIDREVPKG 3szg D 2.25 BS03 AMP D 1 G366 V367 S368 L399 R462 G366 V367 S368 L399 R456 6.3.5.1 0003952,0004359,0005524,0005737,0005886,0008795,0009274,0009435,0016874,0042802 P9WJJ3 22280445 681 MNFYSAYQHGFVRVAACTHHTTIGDPAANAASVLDMARACHDDGAALAVFPELTLSGYSIEDVLLQDSLLDAVEDALLDLVTESADLLPVLVVGAPLRHRHRIYNTAVVIHRGAVLGVVPKSYLPTYREFYERRQMAPGDGERGTIRIGGADVAFGTDLLFAASDLPGFVLHVEIAEDMFVPMPPSAEAALAGATVLANLSGSPITIGRAEDRRLLARSASARCLAAYVYAAAGEGESTTDLAWDGQTMIWENGALLAESERFPKGVRRSVADVDTELLRSERLRMGTFDDNRRHHRELTESFRRIDFALDPPAGDIGLLREVERFPFVPADPQRLQQDCYEAYNIQVSGLEQRLRALDYPKVVIGVSGGLDSTHALIVATHAMDREGRPRSDILAFALPGFKNNAIKLARALGVTFSEIDIGDTARLMLHTIGHPYSVGEKVYDVTFENVQAGLRTDYLFRIANQRGGIVLGTGDLSELALGWSTYGVGDQMSHYNVNAGVPKTLIQHLIRWVISAGEFGEKVGEVLQSVLDTEIEAKVGPFALQDFSLFQVLRYGFRPSKIAFLAWHAWNDAERGNWPPGFPKSERPSYSLAEIRHWLQIFVQRFYSFSQFKRSALPNGPKVSHGGALSPRGDWRAPSDMSARIWLDQIDREVPKG 3szq A 2.353 BS03 AMP A 1 L38 Y41 D63 M64 F65 H138 P141 S142 M143 H147 H149 L7 Y10 D32 M33 F34 H107 P110 S111 M112 H116 H118 3.6.1.71,3.6.1.72 0003824 O74859 21984210 1 QSFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLTHVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALCNYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTSNLPTRGTLTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSV 3t5m A 1.749 BS01 AMP A 1 G85 A112 F177 W180 E269 H303 G87 A114 F179 W182 E271 H305 ? 0000166,0016787 A0A6L8PEJ7 22516613 801 NAMPLPKSLKYGDTIGIYSPSSPVTYTSPKRFERAKSYLLQKGFHILEGSLTGRYDYYRSGSIQERAKELNALIRNPNVSCIMSTIGGMNSNSLLPYIDYDAFQNNPKIMIGYADATALLLGIYAKTGIPTFYGPALVPSFGEFEPFVDDTYKYFLETLLHDQALPYNIKQPLFWSDEFINWEEKTKEKELRPNNWISVTNGQATGRVIGGNLNTIQGIWGSPYMPCIQEGDILFIEDSSKDAATIERSFSFLKINGVFDKVSGIILGKHEQFDDCGTNRKPYEILLEVLQNQRIPLLADFDCCHTHPMITMPIGVQVKMDATNKTIHILEKWKI 3t5m B 1.749 BS01 AMP B 1 I84 G85 A112 F177 W180 E269 H303 I84 G85 A112 F177 W180 E269 H303 ? 0000166,0016787 A0A6L8PEJ7 22516613 801 MPLPKSLKYGDTIGIYSPSSPVTYTSPKRFERAKSYLLQKGFHILEGSLTGRYDYYRSGSIQERAKELNALIRNPNVSCIMSTIGGMNSNSLLPYIDYDAFQNNPKIMIGYADATALLLGIYAKTGIPTFYGPALVPSFGEFEPFVDDTYKYFLETLLHDQALPYNIKQPLFWSDEFINWEEKTKEKELRPNNWISVTNGQATGRVIGGNLNTIQGIWGSPYMPCIQEGDILFIEDSSKDAATIERSFSFLKINGVFDKVSGIILGKHEQFDDCGTNRKPYEILLEVLQNQRIPLLADFDCCHTHPMITMPIGVQVKMDATNKTIHILEKWKI 3tdh C 2.3 BS01 AMP C 1 T195 M199 K200 V220 S221 T309 S311 D312 T190 M194 K195 V215 S216 T304 S306 D307 ? 0004679,0005515,0005524,0005634,0005641,0005737,0005829,0005886,0006357,0006914,0007031,0016208,0019887,0019901,0030447,0031588,0042802,0043539,0045722,1904547,2000217 Kd=55uM -logKd/Ki=4.26, Kd=55uM P12904 22019086 323 DSQEKVSIEQQLAVESIRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRPLFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYILLGS 3tj7 A 2.1 BS01 AMP A 1 H36 H56 Y61 M89 H37 H57 Y62 M90 ? 0000166 A0A6L8P3N5 501 AMTQEIEIEFKNIVTEEEFHALCKSFSIEVFTKQVNHYFETPNSSLKEAGSALRIRHKGETYTLTLKQPAEVGLLETHQVVTENEAKMMMETNVIISGAVMNQLCKLQIPVSALTYMGSLTTERAETLFEGGTLVFDHSFYYNHDDYEIEFEVQDEETGKAAFIHLLKQHNIPIRH 3tj7 B 2.1 BS01 AMP B 1 H36 H56 Y61 K86 E90 H37 H57 Y62 K87 E91 ? 0000166 A0A6L8P3N5 501 AMTQEIEIEFKNIVTEEEFHALCKSFSIEVFTKQVNHYFETPNSSLKEAGSALRIRHKGETYTLTLKQPAEVGLLETHQVVTENEAKMMMETNVIISGAVMNQLCKLQIPVSALTYMGSLTTERAETLFEGGTLVFDHSFYYNHDDYEIEFEVQDEETGKAAFIHLLKQHNIPIRH 3tj7 C 2.1 BS01 AMP C 1 H36 H56 Y61 M89 E90 H37 H57 Y62 M90 E91 ? 0000166 A0A6L8P3N5 501 AMTQEIEIEFKNIVTEEEFHALCKSFSIEVFTKQVNHYFETPNSSLKEAGSALRIRHKGETYTLTLKQPAEVGLLETHQVVTENEAKMMMETNVIISGAVMNQLCKLQIPVSALTYMGSLTTERAETLFEGGTLVFDHSFYYNHDDYEIEFEVQDEETGKAAFIHLLKQHNIPIRHT 3tj7 D 2.1 BS01 AMP D 1 H36 H56 Y61 K86 M89 H38 H58 Y63 K88 M91 ? 0000166 A0A6L8P3N5 501 NAMTQEIEIEFKNIVTEEEFHALCKSFSIEVFTKQVNHYFETPNSSLKEAGSALRIRHKGETYTLTLKQPAEVGLLETHQVVTENEAKMMMETNVIISGAVMNQLCKLQIPVSALTYMGSLTTERAETLFEGGTLVFDHSFYYNHDDYEIEFEVQDEETGKAAFIHLLKQHNIPIR 3tlx A 2.75 BS03 AMP A 1 T59 G60 L63 K85 L86 V87 V92 G113 Q120 R199 T52 G53 L56 K78 L79 V80 V85 G106 Q113 R192 K41 R116 R155 R188 R199 K34 R109 R148 R181 R192 2.7.4.3 0004017,0005524,0005737,0005739,0005829,0006091,0006139,0016301,0016310,0016776,0019205,0046940 Q8IJV6 245 FSTIDLLNELKRRYACLSKPDGRYIFLGAPGSGKGTQSLNLKKSHCYCHLSTGDLLREAAEKKTELGLKIKNIINEGKLVDDQMVLSLVDEKLKTPQCKKGFILDGYPRNVKQAEDLNKLLQKNQTKLDGVFYFNVPDEVLVNRISGRLIHKPSGRIYHKIFNPPKVPFRDDVTNEPLIQREDDNEDVLKKRLTVFKSETSPLISYYKNKNLLINLDATQPANDLEKKISQHIDG 3tlz A 1.5 BS01 AMP A 1 G91 S118 P143 F186 R246 E277 H311 G85 S112 P137 F180 R240 E271 H305 ? 0016787,0030153,0042802 Q47511 22388748 500 PLLAAPLAVGDTIGFFSSSAPATVTAKNRFFRGVEFLQRKGFKLVSGKLTGKTDFYRSGTIKERAQEFNELVYNPDITCIMSTIGGDNSNSLLPFLDYDAIIANPKIIIGYSDTTALLAGIYAKTGLITFYGPALIPSFGEHPPLVDITYESFIKILTRKQSGIYTYTLPEKWSDESINFNENKILRPKKLYKNNCAFYGSGKVEGRVIGGNLNTLTGIWGSEWMPEIRNGDILFIEDSRKSIATVERLFSMLKLNRVFDKVSAIILGKHELFDCAGSKRRPYEVLTEVLDGKQIPVLDGFDCSHTHPMLTLPLGVKLAIDFDNKNISITEQYLS 3tlz B 1.5 BS01 AMP B 1 G91 S118 F186 R246 E277 H311 G85 S112 F180 R240 E271 H305 ? 0016787,0030153,0042802 Q47511 22388748 500 PLLAAPLAVGDTIGFFSSSAPATVTAKNRFFRGVEFLQRKGFKLVSGKLTGKTDFYRSGTIKERAQEFNELVYNPDITCIMSTIGGDNSNSLLPFLDYDAIIANPKIIIGYSDTTALLAGIYAKTGLITFYGPALIPSFGEHPPLVDITYESFIKILTRKQSGIYTYTLPEKWSDESINFNENKILRPKKLYKNNCAFYGSGKVEGRVIGGNLNTLTGIWGSEWMPEIRNGDILFIEDSRKSIATVERLFSMLKLNRVFDKVSAIILGKHELFDCAGSKRRPYEVLTEVLDGKQIPVLDGFDCSHTHPMLTLPLGVKLAIDFDNKNISITEQYLS 3tnj A 2.0 BS01 AMP A 1 A10 V11 D12 H39 V40 V113 G114 H116 T128 A9 V10 D11 H38 V39 V104 G105 H107 T111 ? 0000166,0005737 Q82VN8 23745136 149 SVYHHILLAVDFSSEDSQVVQKVRNLASQIGARLSLIHVLDYGTAIPLDTETTYDAMLDVEKQKLSQIGNTLGIDPAHRWLVWGEPREEIIRIAEQENVDLIVVGSHLGSTANSVLHYAKCDVLAVRLRD 3ttf A 1.92 BS04 AMP A 1 H479 D502 F598 E615 A619 E623 G697 V698 N701 G726 D727 H379 D402 F498 E515 A519 E523 G597 V598 N601 G626 D627 3.6.1.7,6.2.-.- 0003725,0008270,0016743,0046872,0046944 A0A0H3JHT3 22153500 747 QIVPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCPACDKEYRDPLDRRFHAQPVACPECGPYLEWVSHGEHAEQEAALQAAIAQLKMGNIVAIKGIGGFHLACDARNSNAVATLRARKHRPAKPLAVMLPVADGLPDAARQLLTTPAAPIVLVDKKYVPELCDDIAPGLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPAISNEQALEDLQGIADGFLIHNRDIVQRMDDSVVRESGEMLRRSRGYVPDALALPPGFKNVPPVLCLGADLKNTFCLVRGEQVVLSQHLGDLSDDGIQTQWREALRLMQNIYNFTPQYVVHDAHPGYVSCQWASEMNLPTQTVLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECEHLGGLPAVALPGGDLAAKQPWRNLLAQCLRFVPEWQNYPETASVAAANWSVLARAIERGINAPLASSCGRLFDAVAAALGCAPATLSYEGEAACALEALAASCDGVTHPVTMPRVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGFAALMREQATMRGITTLVFSGGVIHNRLLRARLAHYLADFTLLFPQSLPAGDGGLSLGQGVIAAARWLAGE 3tv1 A 1.9 BS01 AMP A 1 A130 P131 P132 F135 F251 Y284 D287 Q288 N309 A127 P128 P129 F132 F248 Y281 D284 Q285 N306 E14 N309 E11 N306 6.5.1.4 0003824,0003963,0005524,0005737,0006396,0016874 P46849 22167800 401 RMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICGATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASTAAVGEYLADQLVLPMALAGAGEFTVAHPSSNLLTNIAVVERFLPVRFSLIETDGVTRVSIE 3tv1 B 1.9 BS01 AMP B 1 S129 A130 P131 F135 F251 Y284 D287 Q288 N309 S126 A127 P128 F132 F248 Y281 D284 Q285 N306 E14 N309 E11 N306 6.5.1.4 0003824,0003963,0005524,0005737,0006396,0016874 P46849 22167800 401 RMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICGATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASTAAVGEYLADQLVLPMALAGAGEFTVAHPSSNLLTNIAVVERFLPVRFSLIETDGVTRVSIE 3tw2 A 1.38 BS01 AMP A 1 I18 D43 I44 G105 Q106 S107 V108 H112 H114 I8 D33 I34 G95 Q96 S97 V98 H102 H104 3.4.22.-,3.9.1.- 0000118,0000166,0003824,0005080,0005515,0005634,0005654,0005737,0005829,0005856,0005886,0006355,0006508,0006915,0007165,0008234,0009154,0016787,0016926,0016929,0043530,0050850,0070062,0072332 P49773 22869114 127 ARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 3ty9 A 3.12 BS01 AMP A 1 E529 K531 H532 R536 E607 R687 F704 K774 K792 E52 K54 H55 R59 E130 R195 F212 K282 K298 6.5.1.3 A3DJ38 22308407 900 SMSRFAADPHWLIYLPPTMSPCETSKKEGMLEHPIEAFEYFRTRGVGKVVCEQKHMGSRAVVIVCKDSQVAEKRFGVLDGTAGICYTRTGRHFFDDMQLEAELIDRVRKVLDKSGFWGDFNTDWVCLDCELMPWSAKAQKLLEEQYSAVGISGRVVLDEAVKLLKQASLNADINELLQRFTERSEMMQKYVEAYRKYCWPVNSIDDLKLAPFHILATEGKVHSDKNHIWHMDTIAKYCTQDDSLIMATNHILVDVTDAESVDKGIKWWEDLTASGGEGMVVKPYDFIVKNELLQPAVKCRGREYLRIIYGPEYTMDENIERLRNRAVGKKRSLALREFSLGMEALERFVRNEPLYRVHECVFGVLALESEPVDPRL 3ty9 B 3.12 BS01 AMP B 1 E529 Q530 K531 H532 R536 E607 R687 F704 K774 K792 E52 Q53 K54 H55 R59 E130 R194 F211 K281 K296 6.5.1.3 A3DJ38 22308407 900 SMSRFAADPHWLIYLPPTMSPCETSKKEGMLEHPIEAFEYFRTRGVGKVVCEQKHMGSRAVVIVCKDSQVAEKRFGVLDGTAGICYTRTGRHFFDDMQLEAELIDRVRKVLDKSGFWGDFNTDWVCLDCELMPWSAKAQKLLEEQYSAVGISGRVVLDEAVKLLKQASLNDINELLQRFTERSEMMQKYVEAYRKYCWPVNSIDDLKLAPFHILATEGKVHSDKNHIWHMDTIAKYCTQDDSLIMATNHILVDVTDAESVDKGIKWWEDLTASGGEGMVVKPYDFIVKNLLQPAVKCRGREYLRIIYGPEYTMDENIERLRNRAVGKKRSLALREFSLGMEALERFVRNEPLYRVHECVFGVLALESEPVDPRL 3ty9 C 3.12 BS01 AMP C 1 E529 Q530 K531 H532 R536 E607 R687 F704 K774 K792 E52 Q53 K54 H55 R59 E130 R196 F213 K283 K298 6.5.1.3 A3DJ38 22308407 900 SMSRFAADPHWLIYLPPTMSPCETSKKEGMLEHPIEAFEYFRTRGVGKVVCEQKHMGSRAVVIVCKDSQVAEKRFGVLDGTAGICYTRTGRHFFDDMQLEAELIDRVRKVLDKSGFWGDFNTDWVCLDCELMPWSAKAQKLLEEQYSAVGISGRVVLDEAVKLLKQASLNNADINELLQRFTERSEMMQKYVEAYRKYCWPVNSIDDLKLAPFHILATEGKVHSDKNHIWHMDTIAKYCTQDDSLIMATNHILVDVTDAESVDKGIKWWEDLTASGGEGMVVKPYDFIVRELLQPAVKCRGREYLRIIYGPEYTMDENIERLRNRAVGKKRSLALREFSLGMEALERFVRNEPLYRVHECVFGVLALESEPVDPRL 3ty9 D 3.12 BS01 AMP D 1 E529 K531 H532 R536 E607 R687 F704 K792 E52 K54 H55 R59 E130 R195 F212 K296 6.5.1.3 A3DJ38 22308407 900 SMSRFAADPHWLIYLPPTMSPCETSKKEGMLEHPIEAFEYFRTRGVGKVVCEQKHMGSRAVVIVCKDSQVAEKRFGVLDGTAGICYTRTGRHFFDDMQLEAELIDRVRKVLDKSGFWGDFNTDWVCLDCELMPWSAKAQKLLEEQYSAVGISGRVVLDEAVKLLKQASLNADINELLQRFTERSEMMQKYVEAYRKYCWPVNSIDDLKLAPFHILATEGKVHSDKNHIWHMDTIAKYCTQDDSLIMATNHILVDVTDAESVDKGIKWWEDLTASGGEGMVVKPYDFIRELLQPAVKCRGREYLRIIYGPEYTMDENIERLRNRAVGKKRSLALREFSLGMEALERFVRNEPLYRVHECVFGVLALESEPVDPRL 3tyx A 2.04 BS01 AMP A 1 I84 G85 S112 W180 E269 H303 I86 G87 S114 W182 E271 H305 ? 0000166,0016787 A0A6L8PEJ7 22516613 401 NAMPLPKSLKYGDTIGIYSPSSPVTYTSPKRFERAKSYLLQKGFHILEGSLTGRYDYYRSGSIQERAKELNALIRNPNVSCIMSTIGGMNSNSLLPYIDYDAFQNNPKIMIGYSDATALLLGIYAKTGIPTFYGPALVPSFGEFEPFVDDTYKYFLETLLHDQALPYNIKQPLFWSDESINWEEKTKEKELRPNNWISVTNGQATGRVIGGNLNTIQGIWGSPYMPCIQEGDILFIEDSSKDAATIERSFSFLKINGVFDKVSGIILGKHEQFDDCGTNRKPYEILLEVLQNQRIPLLADFDCCHTHPMITMPIGVQVKMDATNKTIHILEKWKI 3tyx B 2.04 BS01 AMP B 1 I84 G85 S112 W180 E269 H303 I83 G84 S111 W179 E268 H302 ? 0000166,0016787 A0A6L8PEJ7 22516613 401 PLPKSLKYGDTIGIYSPSSPVTYTSPKRFERAKSYLLQKGFHILEGSLTGRYDYYRSGSIQERAKELNALIRNPNVSCIMSTIGGMNSNSLLPYIDYDAFQNNPKIMIGYSDATALLLGIYAKTGIPTFYGPALVPSFGEFEPFVDDTYKYFLETLLHDQALPYNIKQPLFWSDESINWEEKTKEKELRPNNWISVTNGQATGRVIGGNLNTIQGIWGSPYMPCIQEGDILFIEDSSKDAATIERSFSFLKINGVFDKVSGIILGKHEQFDDCGTNRKPYEILLEVLQNQRIPLLADFDCCHTHPMITMPIGVQVKMDATNKTIHILEKWKI 3u1b A 1.604 BS01 AMP A 1 G85 S112 F177 W180 E269 H303 G88 S115 F180 W183 E272 H306 ? 0000166,0016787 A0A6L8PEJ7 22516613 401 SNAMPLPKSLKYGDTIGIYSPSSPVTYTSPKRFERAKSYLLQKGFHILEGSLTGRYDYYRSGSIQERAKELNALIRNPNVSCIMSTIGGMNSNSLLPYIDYDAFQNNPKIMIGYSDATALLLGIYAKTGIPTFYGPALVPSFGEFEPFVDDTYKYFLETLLHDQALPYNIKQPLFWSDEFINWEEKTKEKELRPNNWISVTNGQATGRVIGGNLNTIQGIWGSPYMPCIQEGDILFIEDSRKDAATIERSFSFLKINGVFDKVSGIILGKHEQFDDCGTNRKPYEILLEVLQNQRIPLLADFDCCHTHPMITMPIGVQVKMDATNKTIHILEKWKI 3u1b B 1.604 BS01 AMP B 1 I84 G85 S112 F177 W180 E269 H303 I84 G85 S112 F177 W180 E269 H303 ? 0000166,0016787 A0A6L8PEJ7 22516613 401 MPLPKSLKYGDTIGIYSPSSPVTYTSPKRFERAKSYLLQKGFHILEGSLTGRYDYYRSGSIQERAKELNALIRNPNVSCIMSTIGGMNSNSLLPYIDYDAFQNNPKIMIGYSDATALLLGIYAKTGIPTFYGPALVPSFGEFEPFVDDTYKYFLETLLHDQALPYNIKQPLFWSDEFINWEEKTKEKELRPNNWISVTNGQATGRVIGGNLNTIQGIWGSPYMPCIQEGDILFIEDSRKDAATIERSFSFLKINGVFDKVSGIILGKHEQFDDCGTNRKPYEILLEVLQNQRIPLLADFDCCHTHPMITMPIGVQVKMDATNKTIHILEKWKI 3uk2 A 2.25 BS01 AMP A 1 P24 M26 H33 L36 F143 G144 K146 D147 T172 V173 L181 P25 M27 H34 L37 F144 G145 K147 D148 T173 V174 L182 M26 H30 H33 E73 D74 K77 K146 S182 S183 R184 M27 H31 H34 E74 D75 K78 K147 S183 S184 R185 6.3.2.1 0003824,0004592,0005524,0005737,0005829,0009058,0015940,0016874 Q2T095 23382856 280 SMKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQEDIEKLQKENVYVLFAPTERDMYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVEIVAAETVRDADGLALSSRNRYLSEAERAEAPELAKTLARVRDAVLDGERDLAAIERRAVAHLSARGWQPDYVSIRRRENLVAPSAAQIEAGDPLVVLTAAKLGATRLIDNLEI 3uk2 B 2.25 BS01 AMP B 1 P24 T25 M26 H33 L36 F143 G144 D147 T172 V173 L181 P25 T26 M27 H34 L37 F144 G145 D148 T173 V174 L182 M26 H30 H33 E73 D74 K77 K146 S182 S183 R184 M27 H31 H34 E74 D75 K78 K147 S183 S184 R185 6.3.2.1 0003824,0004592,0005524,0005737,0005829,0009058,0015940,0016874 Q2T095 23382856 280 SMKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQEDIEKLQKENVYVLFAPTERDMYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVEIVAAETVRDADGLALSSRNRYLSEAERAEAPELAKTLARVRDAVLDGERDLAAIERRAVAHLSARGWQPDYVSIRRRENLVAPSAAQIEAGDPLVVLTAAKLGATRLIDNLEI 3uq6 A 2.3 BS02 AMP A 1 T265 G267 K268 V286 F289 A329 I333 T263 G265 K266 V284 F287 A327 I331 R132 D302 R130 D300 0004001,0006166,0016301 23275171 402 DLSEGYVFGMGNPLLDIIVDADDFMYRKYNLKKDNIVLAEEKHMTIYDEIQKKKKLNYIAGGATLNTVKMIQWIIQKPFVCSYVGCIGADIQGKYIKNDCSALDLVTEFQIAEEPLMTGKVAVLVSEKLRSMVTYLGAACDLSLAHIEQPHVWSLVEKAQVYYIAGFVINTCYEGMLKIAKHSLENEKLFCFNLSAPFLSQFNTKEVDEMISYSNIVFGNESEAEAYGEVHGLLEDTVHATARYIADLPFADGKKRKRLVIITRGKNPLLYTDSSDSEIHQFMVEQFKDDQIIDTNGAGDAFAAGFIADYIRGKPMITSLHAAVKAAAYIICRSGFSLGSRDSYS 3uq6 B 2.3 BS02 AMP B 1 T265 G267 A300 A329 I333 T258 G260 A287 A316 I320 D302 D289 0004001,0006166,0016301 23275171 402 LSEGYVFGMGNPLLDIIVDADDFMYRKYNLKKDNIVLAEEKHMTIYDEIQKKKKLNYIAGGATLNTVKMIQWIIQKPFVCSYVGCIGADIQGKYIKNDCSALDLVTEFQIAEEPLMTGKVAVLVSSMVTYLGAACDLSLAHIEQPHVWSLVEKAQVYYIAGFVINTCYEGMLKIAKHSLENEKLFCFNLSAPFLSQFNTKEVDEMISYSNIVFGNESEAEAYGEVHGLLEDTVHATARYIADLPFADGKKRKRLVIITRGKNPLLYTDSSDSEIHQFMVEIIDTNGAGDAFAAGFIADYIRGKPMITSLHAAVKAAAYIICRSGFSLGSRDSY 3uq8 A 1.7 BS02 AMP A 1 L82 K116 R137 E174 R201 Y226 V289 K291 L80 K114 R135 E172 R199 Y224 V287 K289 E114 K116 D118 Y226 K315 E112 K114 D116 Y224 K313 6.5.1.2 0003911 P43813 22230472 700 NIQTQLDNLRKTLRQYEYEYHVLDNPSVPDSEYDRLFHQLKALELEHPEFLTSDSPTQRVGAKPLSGFSQIRHEIPMLSLDNAFSDAEFNAFVARIEDRLILLPAPLTFCCEPKLDGLAVSILYVNGELTQAATRGDGTTGEDITANIRTIRNVPLQLLTDNPPARLEVRGEVFMPHAGFERLNKYALEHNEKTFANPRNAAAGSLRQLDPNITSKRPLVLNAYGIGIAEGVDLPTTHYARLQWLKSIGIPVNPEIRLCNGADEVLGFYRDIQNKRSSLGYDIDGTVLKINDIALQNELGFISKAPRWAIAYKFPAQEELTL 3uy4 A 1.851 BS01 AMP A 1 P28 M30 H37 L40 M145 G146 D149 I174 I175 K183 P29 M31 H38 L41 M146 G147 D150 I175 I176 K184 M30 H34 H37 R76 D77 M80 K148 S184 S185 R186 M31 H35 H38 R77 D78 M81 K149 S185 S186 R187 6.3.2.1 0004592,0005524,0005737,0005829,0015940,0016874 Q9PIK2 301 AMQVITSVKEAKQIVKDWKSHQLSIGYVPTMGFLHDGHLSLVKHAKTQDKVIVSIFVNPMQFGPNEDFSSYPRDLERDIKMCQDNGVDMVFIPDATQMYLKNFSTYVDMNTITDKLCGAKRPGHFRGVCTVLTKFFNILNPDIVYMGQKDAQQCVVVRHMVDDLNFDLKIQICPIIREEDGLAKSSRNVYLSKEERKASLAISQSIFLAEKLVREGEKNTSKIIQAMKDILEKEKLIKIDYIELVDFNTMENIENITDNVLGAVAAFVGKTRLIDNFLVQGLK 3vbf A 2.6 BS01 AMP A 1 T28 Q30 T28 Q30 2.7.7.48,3.4.22.28,3.4.22.29,3.6.1.15 B2ZUN0 22388738 302 GDRVADVIESSIGDSVSRALTHALPAPTGQNTQVSSHRLDTGKVPALQAAEIGASSNASDESMIETRCVLNSHSTAETTLDSFFSRAGLVGEIDLPLKGTTNPNGYANWDIDITGYAQMRRKVELFTYMRFDAEFTFVACTPTGEVVPQLLQYMFVPPGAPKPDSRESLAWQTATNPSVFVKLSDPPAQVSVPFMSPASAYQWFYDGYPTFGEHKQEKDLEYGAMPNNMMGTFSVRTVGTSKSKYPLVVRIYMRMKHVRAWIPRPMRNQNYLFKANPNYAGNSIKPTGASRTAITTL 3vgj A 2.212 BS02 AMP A 1 D61 G62 F63 E64 H70 A72 Q73 G207 D209 H235 M237 L238 K247 M248 D42 G43 F44 E45 H51 A53 Q54 G188 D190 H216 M218 L219 K228 M229 6.1.1.1 0000166,0004812,0004831,0005524,0005737,0006412,0006418,0006437,0044164,0044650,0046789,0046872 Q8IAR7 22068597 402 EESKIEDVDKILNDILSISSECIQPDELRVKLLLKRKLICYDGFEPSGRMHIAQGLLKSIIVNKLTSNGCTFIFWIADWFAHLNNKMSGDLKKIKKVGSYFIEVWKSCGMNMENVQFLWASEEINKKPNEYWSLVLDISRSFNINRMKRCLKIMGRSEGEENYCSQILYPCMQCADIFFLNVDICQLGIDQRKVNMLAREYCDIKKIKKKPVILSHGMLPGLLEGQEKMSKSDENSAIFMDDSESDVNRKIKKAYCPPNVIENNPIYAYAKSIIFPSYNEFNLVRKEKNGGDKTYYTLQELEHDYVNGFIHPLDLKDNVAMYINKLLQPVRDHFQNNIEAKNLLNEIKKYKVT 3vgj B 2.212 BS02 AMP B 1 D61 G62 F63 E64 A72 L206 G207 D209 H235 M237 L238 K247 M248 D44 G45 F46 E47 A55 L189 G190 D192 H218 M220 L221 K230 M231 6.1.1.1 0000166,0004812,0004831,0005524,0005737,0006412,0006418,0006437,0044164,0044650,0046789,0046872 Q8IAR7 22068597 402 AQEESKIEDVDKILNDILSISSECIQPDELRVKLLLKRKLICYDGFEPSGRMHIAQGLLKSIIVNKLTSNGCTFIFWIADWFAHLNNKMSGDLKKIKKVGSYFIEVWKSCGMNMENVQFLWASEEINKKPNEYWSLVLDISRSFNINRMKRCLKIMGRSEGEENYCSQILYPCMQCADIFFLNVDICQLGIDQRKVNMLAREYCDIKKIKKKPVILSHGMLPGLLEGQEKMSKSDENSAIFMDDSESDVNRKIKKAYCPPNVIENNPIYAYAKSIIFPSYNEFNLVRKEKNGGDKTYYTLQELEHDYVNGFIHPLDLKDNVAMYINKLLQPVRDHFQNNIEAKNLLNEIKKYKVTK 3vnr A 1.75 BS01 AMP A 1 G281 E282 K283 G306 Y307 G308 T310 D401 Y413 R416 K507 G264 E265 K266 G289 Y290 G291 T293 D377 Y389 R392 K483 601 TSDPIARNSDLVSLFREVAATAPERTALSAEDDRISYGRLDAWSDAVARTLLAEGVRPGDRVALRMSPGAEAIVAILAILKCGAAYVPVDLRNPVSRSDFILADSGASALIGEPHEGCAVTRVVRTAAVAECKDAEPPGPGAEDMAYVIYTSPKGVPVRHANVLALLAGAPSVFDFSGDDRWLLFHSLSFDFSVWEIWGAFSTGAELVVLPHWAARTPEQYLAVIIDRGVTVINQTPTAFLALTEAAVRGGRDVSGLRYVIFGGEKLTAPMLRPWAKAFGLDRPRLVNGYGITETTVFTTFEEITEAYLAQDASIIGRALPSFGTRVVGDDGRDVAPGETGELWLSGAQLAEGYLRRPELTAEKFPEVSVRYYRTGDLVSELPDGRFAYEGRADLQIKLRGYRIELSDIETAVRRHDDVVDAVVTVREFKPGDLRLVCAYVAREGSATTARELRNHIKTLLPAYMHPARYLPLPGLPRTVNGKVDRAAVARSW 3vns A 2.001 BS01 AMP A 1 G281 E282 K283 G306 Y307 G308 T310 D401 Y413 R416 K507 G269 E270 K271 G294 Y295 G296 T298 D381 Y393 R396 K487 601 TSDPIARNSDLVSLFREVAATAPERTALSAEDDRISYGRLDAWSDAVARTLLAEGVRPGDRVALRMSPGAEAIVAILAILKCGAAYVPVDLRNPVSRSDFILADSGASALIGEPHEGCAVTRVVRTAAVAECKDAEPAPGPGAEDMAYVIYTSGTGNPKGVPVRHANVLALLAGAPSVFDFSGDDRWLLFHSLSFDFSVWEIWGAFSTGAELVVLPHWAARTPEQYLAVIIDRGVTVINQTPTAFLALTEAAVRGGRDVSGLRYVIFGGEKLTAPMLRPWAKAFGLDRPRLVNGYGITETTVFTTFEEITEAYLAQDASIIGRALPSFGTRVVGDDGRDVAPGETGELWLSGAQLAEGYLRRPELTAEKFPEVVRYYRTGDLVSELPDGRFAYEGRADLQIKLRGYRIELSDIETAVRRHDDVVDAVVTVREFKPGDLRLVCAYVAREGSATTARELRNHIKTLLPAYMHPARYLPLPGLPRTVNGKVDRAAVARSW 3vqx A 2.3 BS01 AMP A 1 R330 H338 L339 M344 E396 L397 S399 G423 R426 R131 H137 L138 M143 E195 L196 S198 G222 R225 6.1.1.26 0000049,0004812,0005524,0043039 Q8PWY1 23275158 501 TKSQTDRLEVLLNPKDEISGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKEGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVYGDTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSGSYYNGISTNL 3vqx B 2.3 BS01 AMP B 1 R330 E332 H338 L339 F342 M344 E396 L397 S399 G423 R426 R132 E134 H139 L140 F143 M145 E188 L189 S191 G215 R218 6.1.1.26 0000049,0004812,0005524,0043039 Q8PWY1 23275158 501 PALTKSQTDRLEVLLNPKDEIGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKEDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSGSYYNGISTNL 3w1b A 2.4 BS02 AMP A 1 K273 K449 K451 K257 K433 K435 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0051103,0071897 P49917 23523427 701 TSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSALEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISITLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTDQFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNEAIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMMSHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILCGTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLEQLRGK 3wjr A 1.864 BS01 AMP A 1 L20 L38 L41 D42 R224 L18 L36 L39 D40 R222 ? 0005515,0005524,0046872,0051604 Q5JII7 24297906 403 EKIKLEHGAGGEIMEELLRDVILKTLTLKSAGGIGLDALDDGATIPFGDKHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAEPIALANSMIIGEGLDMEVLKRVLKSMDETAREVPVPIVTGDTKVVEDKIEMFVITAGIGIAEHPVSDAGAKVGDAVLVSGTIGDHGIALMSHREGIAFETELKSDVAPIWDVVKAVAETIGWENIHAMKDPTRAGLSNALNEIARKSNVGILVREADIPIRPEVRAASEMLGISPYDVANEGKVVMVVAREYAEEALEAMRKTEKGRNAAIIGEVIADYRGKVLLETGIGGKRFMEPPEGDPVPRIC 3wuh A 2.937 BS02 AMP A 1 S172 G173 G199 D203 M215 A217 R218 E221 G325 S328 N329 S360 S132 G133 G159 D163 M175 A177 R178 E181 G271 S274 N275 S298 2.3.1.234 0000049,0002949,0005739,0005759,0006400,0008033,0008252,0008270,0016746,0016747,0046872,0061711,0070525,0072670 P43122 25084372 502 KGYKVLAIETSCDDTCVSVLDRFSKSAAPNVLANLKDTLDKAHIHHQARIGPLTERALIESNAREGIDLICVTRGPGMPGSLSGGLDFAKGLAVAWNKPLIGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFVLSRAIDDHEILCDTIDIAVGDSLDKCGRELGFKGTMIAREMEKFINQDINDQDFALKLEMPRNMLSFSFSAFITALRTNLTKLGKTPEREIRSIAYQVQESVFDHIINKLKHVLKSQPEKFKNVREFVCSGGVSSNQRLRTKLETELFNFYYPPMDLCSDNSIMIGWAGIEIWESLRLVSDLDICPIRQWPLNDLLSVDGWRTDQ 3wuh B 2.937 BS02 AMP B 1 S172 G173 D203 M215 A217 R218 E221 G325 N329 S131 G132 D162 M174 A176 R177 E180 G277 N281 2.3.1.234 0000049,0002949,0005739,0005759,0006400,0008033,0008252,0008270,0016746,0016747,0046872,0061711,0070525,0072670 P43122 25084372 502 KGYKVLAIETSCDDTCVSVLDRFSKSAAPNVLANLKDTLKAHIHHQARIGPLTERALIESNAREGIDLICVTRGPGMPGSLSGGLDFAKGLAVAWNKPLIGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFVLSRAIDDHEILCDTIDIAVGDSLDKCGRELGFKGTMIAREMEKFINQDINDQDFALKLEMPSKRNMLSFSFSAFITALRTNLTKLGKTEIQELPEREIRSIAYQVQESVFDHIINKLKHVLKSQPEKFKNVREFVCSGGVSSNQRLRTKLETELFNFYYPPMDLCSDNSIMIGWAGIEIWESLRLVSDLDICPIRQWPLNDLLSVDGWRTDQ 3wvr B 2.175 BS01 AMP B 1 K185 S192 G208 E243 R244 Y245 H246 V320 T330 K185 S192 G208 E243 R244 Y245 H246 V320 T330 ? 0005524,0046872 A0A0A6YVN3 25402768 504 MRLLVGNDWSEELAEPTGSTGWAVQRLVWFARDGDVLVLPVAPQEEFLAYVTSLTGTRRSSLTVVVPPPGRLGAGALTADRLADPRFLAALREAFAGRPVHEVFALWPDAVVADLADALGCPEALEGHDFLTQSGGLIGSSKAAFRALAAGAGVALPAGAVCADRRRAHRHVTRLLDEGSPVILKQDYGSGSDGNEILSRTPGLALRGARALRVLADSAALDAYLDERWDWLTEGGRHRVVVERYHPGSRAYFAEFWISDGGVRLGGHGEMRYRPLPDSQVMPAPDLDQAQLDDLVEGGRRLCVALHALGYRGVLSADAVVTPAGEVLFTEHNGRATGSTHIYEIVGKRVVGPGFGTDRILLERVWPEGWEAPSFAGALTRLRDSGHLYDPETRRGAVILAAYNTHRKGVMLCYVAEDLEAALHREESVS 3wvr C 2.175 BS01 AMP C 1 K185 S192 G208 E243 R244 Y245 H246 M271 T330 E331 K185 S192 G208 E243 R244 Y245 H246 M271 T330 E331 ? 0005524,0046872 A0A0A6YVN3 25402768 507 MRLLVGNDWSEELAEPTGSTGWAVQRLVWFARDGDVLVLPVAPQEEFLAYVTSLTGTRRSSLTVVVPPPGRLGAGALTADRLADPRFLAALREAFAGRPVHEVFALWPDAVVADLADALGCPEALEGHDFLTQSGGLIGSSKAAFRALAAGAGVALPAGAVCADRRRAHRHVTRLLDEGSPVILKQDYGSGSDGNEILSRTPGLALRGARALRVLADSAALDAYLDERWDWLTEGGRHRVVVERYHPGSRAYFAEFWISDGGVRLGGHGEMRYRPLPDSQVMPAPDLDQAQLDDLVEGGRRLCVALHALGYRGVLSADAVVTPAGEVLFTEHNGRATGSTHIYEIVGKRVVGPGFGTDRILLERVWPEGWEAPSFAGALTRLRDSGHLYDPETRRGAVILAAYNTHRKGVMLCYVAEDLEAALHREESVSRLF 3wvr D 2.175 BS01 AMP D 1 K185 G191 S192 G208 E243 R244 Y245 H246 V320 T330 K185 G191 S192 G208 E243 R244 Y245 H246 V320 T330 ? 0005524,0046872 A0A0A6YVN3 25402768 506 MRLLVGNDWSEELAEPTGSTGWAVQRLVWFARDGDVLVLPVAPQEEFLAYVTSLTGTRRSSLTVVVPPPGRLGAGALTADRLADPRFLAALREAFAGRPVHEVFALWPDAVVADLADALGCPEALEGHDFLTQSGGLIGSSKAAFRALAAGAGVALPAGAVCADRRRAHRHVTRLLDEGSPVILKQDYGSGSDGNEILSRTPGLALRGARALRVLADSAALDAYLDERWDWLTEGGRHRVVVERYHPGSRAYFAEFWISDGGVRLGGHGEMRYRPLPDSQVMPAPDLDQAQLDDLVEGGRRLCVALHALGYRGVLSADAVVTPAGEVLFTEHNGRATGSTHIYEIVGKRVVGPGFGTDRILLERVWFAGALTRLRDSGHLYDPETRRGAVILAAVMLCYVAEDLEAALHREESVS 3x01 A 2.15 BS01 AMP A 1 F139 N203 V204 K214 L282 D369 F100 N164 V165 K175 L241 D295 K150 D278 K111 D237 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 501 KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPEQYSKRFNEFMSNILT 3x01 A 2.15 BS02 AMP A 2 K96 Y98 S154 A158 H161 R188 Y197 K65 Y67 S115 A119 H122 R149 Y158 K150 D278 K111 D237 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 502 KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPEQYSKRFNEFMSNILT 3x01 A 2.15 BS03 AMP A 3 Q293 E297 Q252 E256 K150 D278 K111 D237 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 503 KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPEQYSKRFNEFMSNILT 3x01 B 2.15 BS01 AMP B 1 F139 V148 N203 V204 K214 F99 V108 N163 V164 K174 K150 D278 K110 D230 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 501 KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKREASDKEKAKDLPTFKDNDFLNEGQLHVGSKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAERFFGPGEFDPSVDVYAMKSHESSPKEVYFMAIIDILNPEQYSKRFNEFMSNILT 3x05 A 2.5 BS01 AMP A 1 F139 K150 N203 V204 K214 L282 I368 D369 F99 K110 N163 V164 K174 L242 I295 D296 K150 D278 K110 D238 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 501 VKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVMRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPTVNPEQYSKRFNEFMSNILT 3x05 A 2.5 BS02 AMP A 2 Y98 S154 H161 R188 Y197 Y66 S114 H121 R148 Y157 K150 D278 K110 D238 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 502 VKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVMRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPTVNPEQYSKRFNEFMSNILT 3x05 B 2.5 BS01 AMP B 1 F139 V148 N203 V204 K214 L282 D369 F99 V108 N163 V164 K174 L237 D282 K150 D278 K110 D233 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 501 VKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVMRNVFSHRLTVHRKYDLKREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAERFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTNPEQYSKRFNEFMSNILT 3x05 B 2.5 BS02 AMP B 2 K96 Y98 S154 H161 R188 Y197 K64 Y66 S114 H121 R148 Y157 K150 D278 K110 D233 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 502 VKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVMRNVFSHRLTVHRKYDLKREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAERFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTNPEQYSKRFNEFMSNILT 3x07 A 2.6 BS01 AMP A 1 F139 V204 L282 F98 V163 L240 K150 D278 K109 D236 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 501 KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRAVFSHRLTVHRKYDLKGSVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILNPEQYSKRFNEFMSNILT 3x07 A 2.6 BS02 AMP A 2 Q293 E297 Q251 E255 K150 D278 K109 D236 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 502 KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRAVFSHRLTVHRKYDLKGSVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILNPEQYSKRFNEFMSNILT 3x07 A 2.6 BS03 AMP A 3 K96 Y98 S154 H161 R188 Y197 K65 Y67 S113 H120 R147 Y156 K150 D278 K109 D236 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 503 KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRAVFSHRLTVHRKYDLKGSVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILNPEQYSKRFNEFMSNILT 3x09 A 2.7 BS01 AMP A 1 F139 V148 N203 V204 K214 F98 V107 N162 V163 K173 K150 D278 K109 D235 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 501 VKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVLSHRLTVHRKYDLKGSTREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTVNPEQYSKRFNEFMSNILT 3x09 A 2.7 BS02 AMP A 2 Q293 E297 Q250 E254 K150 D278 K109 D235 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 502 VKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVLSHRLTVHRKYDLKGSTREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTVNPEQYSKRFNEFMSNILT 3x09 A 2.7 BS03 AMP A 3 Y98 S154 H161 R188 Y197 Y66 S113 H120 R147 Y156 K150 D278 K109 D235 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 503 VKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVLSHRLTVHRKYDLKGSTREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTVNPEQYSKRFNEFMSNILT 3x09 B 2.7 BS01 AMP B 1 F139 V148 K150 N203 V204 K214 L282 F99 V108 K110 N163 V164 K174 L239 K150 D278 K110 D235 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 501 KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVLSHRLTVHRKYDLKGVAREASDKEKAKDLPTFKDNDFLNEGQKHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAERFFGPGEFDPSVDVYAMKSHESSPKEVYFMAIIDILTPNPEQYSKRFNEFMSNILT 3x0b A 2.6 BS01 AMP A 1 F139 N203 V204 K214 D369 F100 N164 V165 K175 D295 K150 D278 K111 D237 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 501 KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIADILTTVNPEQYSKRFNEFMSNILT 3x0b A 2.6 BS02 AMP A 2 Q293 E297 Q252 E256 K150 D278 K111 D237 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 502 KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIADILTTVNPEQYSKRFNEFMSNILT 3x0b A 2.6 BS03 AMP A 3 K96 Y98 S154 A158 H161 Y197 K65 Y67 S115 A119 H122 Y158 K150 D278 K111 D237 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 503 KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIADILTTVNPEQYSKRFNEFMSNILT 3x0b B 2.6 BS01 AMP B 1 F139 V148 N203 V204 D216 L282 D369 F99 V108 N163 V164 D176 L234 D280 K150 D278 K110 D230 2.7.1.149 0005515,0005524,0005525,0005634,0005654,0005737,0005776,0005783,0005789,0005829,0005886,0006629,0007166,0010506,0016301,0016308,0016309,0016310,0042803,0046488,0046627,0046854,0052742,0061909,1902635,2000786 P78356 26774281 501 KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKAREASDKEKAKDLPTFKDNDFLNEGQKHVSKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIADILTNPEQYSKRFNEFMSNILT 3zet B 2.31 BS01 AMP B 1 H115 S136 G137 G163 F166 D167 P181 G267 G268 N272 H115 S136 G137 G163 F166 D167 P181 G267 G268 N272 2.3.1.234 0000166,0002949,0005506,0005737,0006400,0008033,0016746,0016747,0046872,0061711,0070525 E8XBD7 23471679 400 MRVLGIETSCDETGIAIYDDKKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEAGLTASDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPMLSKMASQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRSNGGDEQTRADIARAFEDAVVDTLMIKCKRALESTGFKRLVMAGGVSANRTLRAKLAEMMQKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGVTADLGVTVRPRWPLAELPAA 4a59 A 2.2 BS01 AMP A 1 M329 G491 G492 G493 A496 L553 M293 G455 G456 G457 A460 L517 3.6.1.15 0005576,0016787,0017111,0020003 Q27893 22130673 700 DTEKRINVGKKHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIGAGKRFAGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEKQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARCMIDEYGVKQCRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVNNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIKGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMIVTGGGMLAAINTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRNAYEAGYSHNLE 4a59 B 2.2 BS01 AMP B 1 M329 G491 G492 G493 A496 L553 M294 G456 G457 G458 A461 L518 3.6.1.15 0005576,0016787,0017111,0020003 Q27893 22130673 700 ADTEKRINVGKKHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIGAGKRFAGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEKQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARCMIDEYGVKQCRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVNNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIKGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMIVTGGGMLAAINTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRNAYEAGYSHNL 4a59 C 2.2 BS01 AMP C 1 M329 G492 G493 A496 L553 M290 G453 G454 A457 L514 3.6.1.15 0005576,0016787,0017111,0020003 Q27893 22130673 700 KRINVGKKHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIGAGKRFAGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEKQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARCMIDEYGVKQCRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVNNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIKGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMIVTGGGMLAAINTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRNAYEAGYSHNLE 4a59 D 2.2 BS01 AMP D 1 G280 M329 G492 G493 A496 L553 G246 M295 G458 G459 A462 L519 3.6.1.15 0005576,0016787,0017111,0020003 Q27893 22130673 700 DADTEKRINVGKKHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIGAGKRFAGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEKQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARCMIDEYGVKQCRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVNNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIKGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMIVTGGGMLAAINTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRNAYEAGYSHNLE 4a59 D 2.2 BS02 AMP D 2 H195 N399 N400 H161 N365 N366 3.6.1.15 0005576,0016787,0017111,0020003 Q27893 22130673 701 DADTEKRINVGKKHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIGAGKRFAGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEKQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARCMIDEYGVKQCRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVNNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIKGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMIVTGGGMLAAINTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRNAYEAGYSHNLE 4azs A 2.15 BS01 AMP A 1 Q226 P229 Y243 F245 V250 K310 L311 L315 M358 I368 Q223 P226 Y232 F234 V239 K299 L300 L304 M347 I357 2.1.1.294,2.7.1.181 0004672,0005524,0006468 Q47592 22970759 1474 DLNTLVSELPEIYQTIFGHPEWDGDAARDCNQRLDLITEQYDNLSRALGRPLNVLDLGCAQGFFSLSLASKGATIVGIDFQQENINVCRALAEENPDFAAEFRVGRIEEVIAALEEGEFDLAIGLSVFHHIVHLHGIDEVKRLLSRLADVTQAVILELAVKEEPFYWGVSQPDDPRELIEQCAFYRLIGEFDTHLSPVPRPMYLVSNHRVLINDFNQPFQHWQNQPYRSRRYFFGEDYVCKFFYYDMPHGILTAEESQRNKYELHNEIKFLTQPPAGFDAPAVLAHGENAQSGWLVMEKLPGRLLSDMLAAGEEIDREKILGSLLRSLAALEKQGFWHDDVRPWNVMVDARQHARLIDFGSIVTTPSWPTNLVQSFFVFVNELFFNLPQPWSNWLYAVWQEPVERWNFVLLLALFEKKAKLPSAEQQRGATEQWIIAQETVL 4b8s A 2.58 BS02 AMP A 1 N305 H352 T353 V440 I449 I453 N304 H351 T352 V439 I448 I452 2.7.1.-,2.7.1.147 0000287,0004340,0005737,0005975,0006006,0006096,0016301,0016310,0016773,0043843,0046872,0051156 Q7M537 23818958 1472 KESLKDRIRLWKRLYVNAFENALNAIPNVKGVLLAYNTNIDAIKYLDKDDLEKRVTEIGKEKVFEIIENPPEKISSIEELLGGILRSIKLGKAMEWFVESEEVRRYLREWGWDELRIGGQAGIMANLLGGVYRIPTIVHVPQNPKLQAELFVDGPIYVPVFEGNKLKLVHPKDAIAEEEELIHYIYEFPRGFQVFDVQAPRENRFIANADDYNARVYMRREFREGFEEITRNVELAIISGLQVLKEYYPDGTTYRDVLDRVESHLNILNRYNVKSHFEFAYTANRRVREALVELLPKFTSVGLNEVELASIMEIIGDEELAKEVLEGHIFSVIDAMNVLMDETGIERIHFHTYGYYLALTQYRGEEVRDALLFASLAAAAKAMKGNLERIEQIRDALSVPTNERAIVLEEELEKEFTEFENGLIDMVDRQLAFVPTKIVASPKSTVGIGDTISSSAFVSEFGMRKR 4blw A 1.95 BS01 AMP A 1 H9 N12 M235 H9 N12 M235 2.1.1.266 0003676,0003723,0005515,0005829,0006364,0008168,0008649,0008988,0015976,0032259,0036307,0070475 P37634 23945937 1281 MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAGAGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPLIARLLLREQDSLQLTELHPSDYPLLRSEFQKDSRARVEKADGFQQLKAKLPPVSRRGLILIDPPYEMKTDYQAVVSGIAEGYKRFATGIYALWYPVVLRQQIKRMIHDLEATGIRKILQIELAVLPDSDRRGMTASGMIVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSWIVPE 4blw B 1.95 BS01 AMP B 1 H9 N12 V199 M235 H9 N12 V199 M235 2.1.1.266 0003676,0003723,0005515,0005829,0006364,0008168,0008649,0008988,0015976,0032259,0036307,0070475 P37634 23945937 1280 MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAGAGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPLIARLLLREQDSLQLTELHPSDYPLLRSEFQKDSRARVEKADGFQQLKAKLPPVSRRGLILIDPPYEMKTDYQAVVSGIAEGYKRFATGIYALWYPVVLRQQIKRMIHDLEATGIRKILQIELAVLPDSDRRGMTASGMIVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSWIVP 4brf B 1.6 BS02 AMP B 1 T53 K80 K82 Q231 N302 L303 Y346 Y350 T17 K44 K46 Q195 N266 L267 Y310 Y314 3.6.1.5 0000166,0016787,0046872 Q5ZUA2 23830739 1399 NPCEKHSCIAVIDAGSTGSRLHIYSYDTDDTNTPIHIEEIWNKKIKPGFASIQPNSVTIDAYLTMLLADAPIHNIPVYFYATAGMRLLPQSQQKKYYDELDYWFRQQSQWQLVEAKTITGNDEALFDWLAVNYKLDTLKSVQNKSVGVMDMGGASVQIVFPMPKNAEISKHNQVELNIYGQNINLYVHSFLGLGQTEMSHQFLNSPSCFANDYPLPDGESGQGNAPSCKEEVTSLMNSVHKVNQQIQPLLALNPVNEWYSIGGISNLASSQLFHFENSELTNQSLLQQGDNQICHQQWDILNGQYPDDEYLYQYCLLSSYYYALMVDGYGINPNQTIHYIPPEQNLDWTIGVVLHRAL 4brn A 1.69 BS01 AMP A 1 S52 T53 R56 G188 G189 Q231 G299 N302 Y346 S16 T17 R20 G152 G153 Q195 G263 N266 Y310 ? 0000166,0016787,0046872 Q5ZUA2 23830739 1393 NPCEKHSCIAVIDAGSTGSRLHIYSYDTDDTNTPIHIEEIWNKKIKPGFASIQPNSVTIDAYLTMLLADAPIHNIPVYFYATAGMRLLPQSQQKKYYDELDYWFRQQSQWQLVEAKTITGNDEALFDWLAVNYKLDTLKSVQNKSVGVMDMGGASVQIVFPMPKNAEISKHNQVELNIYGQNINLYVHSFLGLGQTEMSHQFLNSPSCFANDYPLPDGESGQGNAPSCKEEVTSLMNSVHKVNQQIQPLLALNPVNEWYSIGGISNLASSQLFHFENSELTNQSLLQQGDNQICHQQWDILNGQYPDDEYLYQYCLLSSYYYALMVDGYGINPNQTIHYIPPEQNLDWTIGVVLHR 4brn B 1.69 BS01 AMP B 1 S52 T53 R56 G188 G189 Q231 G299 N302 Y346 Y350 S16 T17 R20 G152 G153 Q195 G263 N266 Y310 Y314 ? 0000166,0016787,0046872 Q5ZUA2 23830739 1395 NPCEKHSCIAVIDAGSTGSRLHIYSYDTDDTNTPIHIEEIWNKKIKPGFASIQPNSVTIDAYLTMLLADAPIHNIPVYFYATAGMRLLPQSQQKKYYDELDYWFRQQSQWQLVEAKTITGNDEALFDWLAVNYKLDTLKSVQNKSVGVMDMGGASVQIVFPMPKNAEISKHNQVELNIYGQNINLYVHSFLGLGQTEMSHQFLNSPSCFANDYPLPDGESGQGNAPSCKEEVTSLMNSVHKVNQQIQPLLALNPVNEWYSIGGISNLASSQLFHFENSELTNQSLLQQGDNQICHQQWDILNGQYPDDEYLYQYCLLSSYYYALMVDGYGINPNQTIHYIPPEQNLDWTIGVVLHRAL 4brq A 1.45 BS01 AMP A 1 T53 R56 K80 Q231 G299 N302 L303 Y346 Y350 T17 R20 K44 Q195 G263 N266 L267 Y310 Y314 3.6.1.5 0000166,0016787,0046872 Q5ZUA2 23830739 1396 NPCEKHSCIAVIDAGSTGSRLHIYSYDTDDTNTPIHIEEIWNKKIKPGFASIQPNSVTIDAYLTMLLADAPIHNIPVYFYATAGMRLLPQSQQKKYYDELDYWFRQQSQWQLVEAKTITGNDEALFDWLAVNYKLDTLKSVQNKSVGVMDMGGASVQIVFPMPKNAEISKHNQVELNIYGQNINLYVHSFLGLGQTEMSHQFLNSPSCFANDYPLPDGESGQGNAPSCKEEVTSLMNSVHKVNQQIQPLLALNPVNEWYSIGGISNLASSQLFHFENSELTNQSLLQQGDNQICHQQWDILNGQYPDDEYLYQYCLLSSYYYALMVDGYGINPNQTIHYIPPEQNLDWTIGVVLHRALE 4brq B 1.45 BS01 AMP B 1 T53 K80 Q231 G299 N302 L303 Y346 Y350 T17 K44 Q195 G263 N266 L267 Y310 Y314 3.6.1.5 0000166,0016787,0046872 Q5ZUA2 23830739 1396 NPCEKHSCIAVIDAGSTGSRLHIYSYDTDDTNTPIHIEEIWNKKIKPGFASIQPNSVTIDAYLTMLLADAPIHNIPVYFYATAGMRLLPQSQQKKYYDELDYWFRQQSQWQLVEAKTITGNDEALFDWLAVNYKLDTLKSVQNKSVGVMDMGGASVQIVFPMPKNAEISKHNQVELNIYGQNINLYVHSFLGLGQTEMSHQFLNSPSCFANDYPLPDGESGQGNAPSCKEEVTSLMNSVHKVNQQIQPLLALNPVNEWYSIGGISNLASSQLFHFENSELTNQSLLQQGDNQICHQQWDILNGQYPDDEYLYQYCLLSSYYYALMVDGYGINPNQTIHYIPPEQNLDWTIGVVLHRALE 4cf7 B 1.594 BS03 AMP B 1 T31 G32 L35 R36 E57 L58 V59 I64 G82 F83 R85 Q89 R150 T31 G32 L35 R36 E57 L58 V59 I64 G82 F83 R85 Q89 R150 K13 R85 R124 R150 R161 K13 R85 R124 R150 R161 2.7.4.3 0004017,0004550,0005524,0005737,0005829,0006139,0009123,0009132,0009165,0016301,0016310,0016776,0019205,0043231,0044209,0046940,0050145 O66490 25580578 1206 MILVFLGPPGAGKGTQAKRLAKEKGFVHISTGDILREAVQKGTPLGKKAKEYMERGELVPDDLIIALIEEVFPKHGNVIFDGFPRTVKQAEALDEMLEKKGLKVDHVLLFEVPDEVVIERLSGRRINPETGEVYHVKYNPPPPGVKVIQREDDKPEVIKKRLEVYREQTAPLIEYYKKKGILRIIDASKPVEEVYRQVLEVIG 4cfe E 3.023 BS01 AMP E 1 T87 L129 V130 I150 H151 R152 T61 L98 V99 I119 H120 R121 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 24352254 1326 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4cfe E 3.023 BS02 AMP E 2 K170 I240 S242 F244 D245 R269 L277 V297 H298 R299 K139 I209 S211 F213 D214 R238 L246 V266 H267 R268 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 24352254 1327 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4cfe E 3.023 BS03 AMP E 3 H151 T200 I204 A205 V225 S226 I312 S314 S316 D317 H120 T169 I173 A174 V194 S195 I281 S283 S285 D286 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 24352254 1328 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4cfe F 3.023 BS01 AMP F 1 T87 T89 D90 V130 I150 R152 T61 T63 D64 V98 I118 R120 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 24352254 1326 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4cfe F 3.023 BS02 AMP F 2 K170 I240 S242 D245 R269 V276 L277 V297 H298 R299 K138 I208 S210 D213 R237 V239 L240 V260 H261 R262 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 24352254 1327 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4cfe F 3.023 BS03 AMP F 3 H151 T200 I204 A205 V225 S226 H298 S314 S316 D317 H119 T168 I172 A173 V193 S194 H261 S277 S279 D280 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 24352254 1328 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4cff E 3.924 BS01 AMP E 1 R70 K170 I240 S242 D245 R269 V276 L277 V297 H298 R299 R44 K144 I214 S216 D219 R243 V250 L251 V271 H272 R273 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 24352254 1326 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4cff E 3.924 BS02 AMP E 2 H151 T200 I204 A205 V225 S226 H298 S314 S316 D317 H125 T174 I178 A179 V199 S200 H272 S288 S290 D291 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 24352254 1327 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4cff F 3.924 BS01 AMP F 1 R70 K170 I240 S242 D245 R269 V276 L277 V297 H298 R299 R44 K138 I208 S210 D213 R237 V244 L245 V265 H266 R267 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 24352254 1325 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 4cff F 3.924 BS02 AMP F 2 H151 T200 I204 A205 V225 S226 H298 I312 S314 S316 D317 H119 T168 I172 A173 V193 S194 H266 I280 S282 S284 D285 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 24352254 1326 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 4cfh E 3.24 BS02 AMP E 1 R69 I239 S241 F243 D244 V275 L276 V296 H297 R298 R46 I216 S218 F220 D221 V252 L253 V273 H274 R275 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 21399626 1325 NSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLT 4cfh E 3.24 BS03 AMP E 2 H150 T199 I203 A204 V224 S225 H297 I311 S313 S315 D316 H127 T176 I180 A181 V201 S202 H274 I288 S290 S292 D293 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 21399626 1326 NSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLT 4co4 B 1.5 BS04 AMP C 1 G27 T29 V63 A64 G27 T29 V45 A46 ? 0005524,0005829,0006808,0030234,0046872 P70731 24846646 120 MKLVMAIIKPFKLDEVREALTSLGIQGLTVSEVKGFFLPKVKVEVAVSDDQYEQVVEAIQKAANTGRIGDGKIFVLDIAQAVRIRTGETNTE 4co4 C 1.5 BS04 AMP C 1 I7 G35 K58 G87 D88 G89 K90 I7 G35 K40 G69 D70 G71 K72 ? 0005524,0005829,0006808,0030234,0046872 P70731 24846646 120 MKLVMAIIKPFKLDEVREALTSLGIQGLTVSEVKGFFLPKVKVEVAVSDDQYEQVVEAIQKAANTGRIGDGKIFVLDIAQAVRIRTGETN 4cs3 A 1.499 BS02 AMP A 1 R330 E332 H338 L339 F342 E396 L397 S398 S399 G421 G423 R142 E144 H150 L151 F154 E208 L209 S210 S211 G233 G235 6.1.1.26 0000049,0004812,0005524,0043039 Q8PWY1 24737732 1459 ALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTELSKQIFRVDKNFCLRPMLAPNLANYLRKLDRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVFGDTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTNLHHHH 4cs9 A 2.01 BS02 AMP A 1 C7 K8 Y9 F23 C5 K6 Y7 F21 ? 0000166,0003746,0005198,0005737,0006414,0030430,0042025,0044423,0046782,0046872 -logKd/Ki=2.10, Kd=8mM Q8QN58 24842877 1172 RKAPCKYEVRGKCNRGSECKFNHNYWSWPDRYLLIRSNYLLNQLLRNTDRGREDRTQDFVLGSTNVVQGYIDDNQSITKAAACYSLHNIIKQLQEVEVRQARDNKLSDSKHVALHNLVLSYMEMSKTPASLINNLKRLPREKLKKLAKLIIDLSAGAE 4cs9 B 2.01 BS02 AMP B 1 K8 F23 K6 F21 ? 0000166,0003746,0005198,0005737,0006414,0030430,0042025,0044423,0046782,0046872 Q8QN58 24842877 1171 RKAPCKYEVRGKCNRGSECKFNHNYWSWPDRYLLIRSNYLLNQLLRNTDRASIISGAGREDRTQDFVLGSTNVVQGYIDDNQSITKAAACYSLHNIIKQLQEVEVRQARDNKLSDSKHVALHNLVLSYMEMSKTPASLINNLKRLPREKLKKLAKLIIDLSAGA 4cs9 C 2.01 BS02 AMP C 1 C7 K8 Y9 F23 C6 K7 Y8 F22 ? 0000166,0003746,0005198,0005737,0006414,0030430,0042025,0044423,0046782,0046872 -logKd/Ki=2.10, Kd=8mM Q8QN58 24842877 1174 SRKAPCKYEVRGKCNRGSECKFNHNYWSWPDRYLLIRSNYLLNQLLRDTDRADGAGREDRTQDFVLGSTNVVQGYIDDNQSITKAAACYSLHNIIKQLQEVEVRQARDNKLSDSKHVALHNLVLSYMEMSKTPASLINNLKRLPREKLKKLAKLIIDLSAGAEND 4cs9 C 2.01 BS03 AMP C 2 Y9 C15 N16 R17 Y8 C14 N15 R16 ? 0000166,0003746,0005198,0005737,0006414,0030430,0042025,0044423,0046782,0046872 -logKd/Ki=2.10, Kd=8mM Q8QN58 24842877 1175 SRKAPCKYEVRGKCNRGSECKFNHNYWSWPDRYLLIRSNYLLNQLLRDTDRADGAGREDRTQDFVLGSTNVVQGYIDDNQSITKAAACYSLHNIIKQLQEVEVRQARDNKLSDSKHVALHNLVLSYMEMSKTPASLINNLKRLPREKLKKLAKLIIDLSAGAEND 4ct9 A 2.14 BS01 AMP A 1 L13 T18 L19 D20 T21 N22 G152 P153 L13 T18 L19 D20 T21 N22 G152 P153 ? 0005524,0046872 Q5SHB0 400 MERAEILGVGTELLYGETLDTNTAEIARSLKPYALKVERTLRVADEVAPLAREVEEAFARARLVVLSGGLGPTPDDVTREAVALALGEPLELDEAVLGEIEAFFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVLLPGPPPEWRPMWQEVLPRLGLPRRPYAERVLKTWGIGESEIVERLGPLFVREEEVEVGTYPKVHGVEVVVRGREDRVAELAERIKKKLLKEVWGEGEMTLAEAVKRRMEREGATLSTMESLTGGLLGAEITRVPGASRFYLGGVVSYSVGAKARFGVPQDLLSRTVSAETARAMAEAARSLFGSTYALATTGVAGPDPLEGEPPGTVYVALAGPTGAEVRRYRFPGDRETVRLRSVYAALALLVT 4d05 A 1.65 BS01 AMP A 1 S23 K25 L26 E64 F97 M155 K173 S24 K26 L27 E65 F98 M156 K174 6.5.1.1 0000166,0003910,0005524,0006260,0006281,0006310 A0A0A6YVN6 25372693 1263 GQPPPIQLATNYRQDIDVTQYYVSEKLDGIRAYWNGHQLISKQGNIFTAPTWFIASFPTTAMDGELWIARQQFETVSGIARTQDNQNEQWKQIKFMIFDLPKSTVSFEQRINKMQTLVTDTNSPYLQMIEQQKIPNTVALFDLLNKVVMGKGEGLMLHHQDALYQTKRSRDLMKLKKFEDAEATVIAYLPGKGKYEGLLGAILVKNEEGVTFKIGSGFSDEERSTPPPIGSLITYRFTGKTNNNIPRFASFVRIRVIY 4d05 B 1.65 BS01 AMP B 1 S23 K25 L26 R30 E64 F97 I128 K173 S19 K21 L22 R26 E60 F93 I124 K167 6.5.1.1 0000166,0003910,0005524,0006260,0006281,0006310 A0A0A6YVN6 25372693 1260 IQLATNYRQDIDVTQYYVSEKLDGIRAYWNGHQLISKQGNIFTAPTWFIASFPTTAMDGELWIARQQFETVSGIARTQDNQNEQWKQIKFMIFDLPKSTVSFEQRINKMQTLVTDTNSPYLQMIEQQKIPNTVALFDLLNKVVMGKGEGLMLHHQDALYQTSRDLMKLKKFEDAEATVIAYLPGKGKYEGLLGAILVKNEEGVTFKIGSGFSDEERSTPPPIGSLITYRFTGKTNNNIPRFASFVRIRV 4d56 A 2.1 BS02 AMP A 1 G274 E275 R276 V298 Y299 G300 P301 T302 D394 Y406 K415 R420 G273 E274 R275 V297 Y298 G299 P300 T301 D393 Y405 K414 R419 T155 F175 T302 E303 K415 R420 T154 F174 T301 E302 K414 R419 ? 0000166,0005737,0005829,0031177,0043041,0044550,0046872 G0WVH3 26096082 1591 FKQSIHQLFETQVERTPEAVAVLSEQGQLTYEELNTKANQLAHYLRTLGVKSETLVGVCVDRSLEMVIGLLAILKAGGAYVPLDPTYPRERLTYMVQDAQISVLVTQTQWSNLISDYQGQVICLDSQWAKIASYSQENLVNTVNPENLAYVIYTSGSTGKPKGVMIEHQSLVNFTKLAIAQYQITTSDRTLQFVSISFDVAAEEIYVTLCSGATLILRTEEMISSIPSFVQKSQDWQITVWSLPTAYWHLLVNELVKSKIALPDSLRLVIIGGERVQPELVRMWFKNVGNFPELINVYGPTEGTIAVSLCRLSQLTESQRNRTEIPIGKSLGENISVYVLDETLKTVPPETPGEIYIGGTALARGYLNRPELTAQKFIQDPFSPSERLYKTGDLGRYLADGNLEYLGRVDHQVKINGFRVELGEIETVLLQHHQVAQAVVIDRRLVAYLVPHSTEENLTVTLQQFLKNKLPSYMIPATFVVL 4d57 A 2.0 BS02 AMP A 1 G274 E275 R276 V298 Y299 G300 P301 T302 D394 K415 R420 G273 E274 R275 V297 Y298 G299 P300 T301 D393 K414 R419 T155 F175 T302 E303 K415 R420 T154 F174 T301 E302 K414 R419 ? 0000166,0005737,0005829,0031177,0043041,0044550,0046872 G0WVH3 26096082 1495 FKQSIHQLFETQVERTPEAVAVLSEQGQLTYEELNTKANQLAHYLRTLGVKSETLVGVCVDRSLEMVIGLLAILKAGGAYVPLDPTYPRERLTYMVQDAQISVLVTQTQWSNLISDYQGQVICLDSQWAKIASYSQENLVNTVNPENLAYVIYTSGSTGKPKGVMIEHQSLVNFTKLAIAQYQITTSDRTLQFVSISFDVAAEEIYVTLCSGATLILRTEEMISSIPSFVQKSQDWQITVWSLPTAYWHLLVNELVKSKIALPDSLRLVIIGGERVQPELVRMWFKNVGNFPELINVYGPTEGTIAVSLCRLSQLTESQRNRTEIPIGKSLGENISVYVLDETLKTVPPETPGEIYIGGTALARGYLNRPELTAQKFIQDPFSPSERLYKTGDLGRYLADGNLEYLGRVDHQVKINGFRVELGEIETVLLQHHQVAQAVVIDRRLVAYLVPHSTEENLTVTLQQFLKNKLPSYMIPATFVVL 4d7a A 1.801 BS01 AMP A 1 G37 G39 G40 D61 D63 R72 K85 F108 V109 I129 D130 P134 G36 G38 G39 D60 D62 R71 K84 F107 V108 I128 D129 P133 6.1.-.- 0005515,0005524,0008641,0016020,0016874,0030955,0031402,0042803,0061503,0061504 Q46927 25897750 401 SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPGFGAATMVTATFGFVAVSHALKKMMAKAARQ 4d7a B 1.801 BS01 AMP B 1 G37 G39 G40 I60 D61 D63 R72 K85 F108 V109 I129 D130 P134 G36 G38 G39 I59 D60 D62 R71 K84 F107 V108 I128 D129 P133 6.1.-.- 0005515,0005524,0008641,0016020,0016874,0030955,0031402,0042803,0061503,0061504 Q46927 25897750 401 SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGFGAATMVTATFGFVAVSHALKKMMAKAARQ 4d7a D 1.801 BS01 AMP D 1 G37 G39 G40 D61 R72 K85 F108 V109 I129 D130 P134 G36 G38 G39 D60 R71 K84 F107 V108 I128 D129 P133 6.1.-.- 0005515,0005524,0008641,0016020,0016874,0030955,0031402,0042803,0061503,0061504 Q46927 25897750 401 SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQGFGAATMVTATFGFVAVSHALKKMMAKAAR 4dg8 A 2.15 BS01 AMP A 1 G283 D284 I285 G306 Y307 G308 P309 T310 D400 F412 K421 R426 G269 D270 I271 G292 Y293 G294 P295 T296 D386 F398 K407 R412 S170 E311 K421 R426 S156 E297 K407 R412 6.2.1.- 0000166,0005737,0031177,0043041,0044550 Q9I4B7 22452656 701 QNSLLDLYAHPTVVARFSEMAALHPHREAIRDRFGSVDYRQLLDSAEQLSDYLLEHYPQPGVCLGVYGEYSRESITCLLAILLSGHHYLYIDLKQPAAWNAELCRQVDCRLILDCSTTPTPANGLPCVPVRHLPAAPASVARPCFAADQIAYINFSSGTTGRPKAIACTHAGITRLCLGQSFLAFAPQMRFLVNSPLSFDAATLEIWGALLNGGCCVLNDLGPLDPGVLRQLIGERGADSAWLTASLFNTLVDLDPDCLGGLRQLLTGGDILSVPHVRRALLRHPRLHLVNGYGPTENTTFTCCHVVTDDDLEEDDIPIGKAIAGTAVLLLDEHGQEIAEPDRAGEIVAFGAGLAQGYRNDAARTRASFVELPYRGRLLRAYRTGDRARYDEQGRLRFIGRGDGQVKLNGYRLDLPALEQRFRRQPGILDCALLVRERNGVKQLLCAWTGKADASPQALLRQLPTWQRPHACVRVEALPLTLDRAALLRRLEEPL 4e6n A 2.39 BS01 AMP A 1 M496 E529 K531 H532 R536 E607 F704 V772 K774 K792 M44 E77 K79 H80 R84 E155 F241 V309 K311 K329 ? A3DJ38 22847431 902 GKKIITTRLMSSITIHEENSIAALEVMSRFAADPHWLIYLPPTMSPCETSKKEGMLEHPIEAFEYFRTRGVGKVVCEQKHMGSRAVVIVCKDSQVAEKRFGVLDGTAGICYTRTGRHFFDDMQLEAELIDRVRKVLDKSGFWGDFNTDWVCLDCELMPWSAKAQKLLEEQYSAVGISGRVVLDEAVKLLKQASLNKGKNADINELLQRFTERSEMMQKYVEAYRKYCWPVNSIDDLKLAPFHILATEGKVHSDKNHIWHMDTIAKYCTQDDSLIMATNHILVDVTDAESVDKGIKWWEDLTASGGEGMVVKPYDFIVKNGRELLQPAVKCRGREYLRIIYGPEYTMDENIERLRNRAVGKKRSLALREFSLGMEALERFVRNEPLYRVHECVFGVLALESEPVDPRL 4e6n C 2.39 BS01 AMP C 1 M496 E529 K531 H532 R536 E607 F704 V772 K774 K792 M44 E77 K79 H80 R84 E155 F241 V309 K311 K329 ? A3DJ38 22847431 902 GKKIITTRLMSSITIHEENSIAALEVMSRFAADPHWLIYLPPTMSPCETSKKEGMLEHPIEAFEYFRTRGVGKVVCEQKHMGSRAVVIVCKDSQVAEKRFGVLDGTAGICYTRTGRHFFDDMQLEAELIDRVRKVLDKSGFWGDFNTDWVCLDCELMPWSAKAQKLLEEQYSAVGISGRVVLDEAVKLLKQASLNKGKNADINELLQRFTERSEMMQKYVEAYRKYCWPVNSIDDLKLAPFHILATEGKVHSDKNHIWHMDTIAKYCTQDDSLIMATNHILVDVTDAESVDKGIKWWEDLTASGGEGMVVKPYDFIVKNGRELLQPAVKCRGREYLRIIYGPEYTMDENIERLRNRAVGKKRSLALREFSLGMEALERFVRNEPLYRVHECVFGVLALESEPVDPRL 4eai C 2.285 BS01 AMP C 1 R69 I239 S241 F243 D244 F272 V275 L276 V296 H297 R298 R44 I209 S211 F213 D214 F237 V240 L241 V261 H262 R263 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 22659875 401 SVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAANLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLT 4eai C 2.285 BS02 AMP C 2 M84 T86 T88 D89 L128 V129 I149 H150 R151 M59 T61 T63 D64 L98 V99 I119 H120 R121 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 22659875 402 SVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAANLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLT 4eai C 2.285 BS03 AMP C 3 H150 T199 I203 A204 V224 S225 H297 S313 S315 D316 H120 T169 I173 A174 V194 S195 H262 S278 S280 D281 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 22659875 403 SVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAANLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLT 4eaj C 2.609 BS03 AMP C 1 H150 T199 I203 A204 V224 S225 H297 I311 S313 D316 H120 T169 I173 A174 V194 S195 H262 I276 S278 D281 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 22659875 403 SVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAANLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLT 4eal C 2.506 BS01 AMP C 1 M84 T86 T88 D89 Q122 L128 V129 I149 H150 R151 M62 T64 T66 D67 Q90 L96 V97 I117 H118 R119 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 22659875 401 SNSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTNLDVSVTKALQHRSVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLT 4eal C 2.506 BS02 AMP C 2 H150 T199 I203 A204 V224 S225 I311 S313 D316 H118 T167 I171 A172 V192 S193 I272 S274 D277 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 22659875 402 SNSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTNLDVSVTKALQHRSVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLT 4eei A 1.921 BS01 AMP A 1 K66 H67 D68 Q212 R301 I303 S306 R310 K66 H67 D68 Q212 R289 I291 S294 R298 H67 S140 H141 K268 E275 H67 S140 H141 K256 E263 4.3.2.2 0000166,0003824,0004018,0005829,0006164,0006189,0009152,0016829,0044208,0044281,0070626 Q5NIQ1 501 MIKRYDVAEISKIWADENKYAKMLEVELAILEALEDRMVPKGTAAEIRARAQIRPERVDEIEKVTKHDIIAFCTSIAEQFTAETGKFFHFGVTSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFGQKFLGAYVEFKRRLKDLKDFQKDGLTVQFSGAVGNYCILTTEDEKKAADILGLPVEEVSTQVIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFEVYEGFKKNPISTENLTGMARMLRSHVSIALENCVLWHERDISHSSAERFYLPDNFGIMVYALRRMKNTIDNLVVQRDIIEDRVRSTSAYLSSFYLHFLVANTPFMREDCYKIVQQVESFSKKLQKVMHDEHNIILDIPEMDFEGIKKTYLKEIDHVFDRSVKAR 4eei B 1.921 BS01 AMP B 1 K66 H67 D68 Q212 R301 I303 S306 R310 K66 H67 D68 Q212 R289 I291 S294 R298 H67 S140 H141 K268 E275 H67 S140 H141 K256 E263 4.3.2.2 0000166,0003824,0004018,0005829,0006164,0006189,0009152,0016829,0044208,0044281,0070626 Q5NIQ1 503 MIKRYDVAEISKIWADENKYAKMLEVELAILEALEDRMVPKGTAAEIRARAQIRPERVDEIEKVTKHDIIAFCTSIAEQFTAETGKFFHFGVTSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFGQKFLGAYVEFKRRLKDLKDFQKDGLTVQFSGAVGNYCILTTEDEKKAADILGLPVEEVSTQVIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFEVYEGFKKNPISTENLTGMARMLRSHVSIALENCVLWHERDISHSSAERFYLPDNFGIMVYALRRMKNTIDNLVVQRDIIEDRVRSTSAYLSSFYLHFLVANTPFMREDCYKIVQQVAFDLESFSKKLQKVMHDEHNIILDIPEMDFEGIKKTYLKEIDHVFDRSVKARGENLY 4efc A 2.0 BS01 AMP A 1 N106 H107 D108 S138 Q139 R350 L352 S355 T356 R359 N95 H96 D97 S127 Q128 R339 L341 S344 T345 R348 H107 T184 H185 S311 K316 E323 H96 T173 H174 S300 K305 E312 4.3.2.2 0000166,0003824,0004018,0005654,0005737,0006164,0006188,0006189,0009152,0016829,0020015,0044208,0046872,0070626 Q38EJ2 501 VDYSVDNPLFALSPLDGRYKRQTKALRAFFSEYGFFRYRVLVEVEYFTALCKDVPTIVPLRSVTDEQLQKLRKITLDCFSVSSAEEIKRLERVTNHDIKAVEYFIKERMDTCGLSHVTEFVHFGLTSQDINNTAIPMMIRDAIVTLYLPALDGIIGSLTSKLVDWDVPMLARTHGQPASPTNLAKEFVVWIERLREQRRQLCEVPTTGKFGGATGNFNAHLVAYPSVNWRAFADMFLAKYLGLKRQQATTQIENYDHLAALCDACARLHVILIDMCRDVWQYISMGFFKQKVKEGEVGSSTMPHKVNPIDFENAEGNLALSNALLNFFASKLPISRLQRDLTDSTVLRNLGVPIGHACVAFASISQGLEKLMISRETISRELSSNWAVVAEGIQTVLRRECYPKPYETLKKLTVTEEQVRNFINGLTDISDDVRAELLAITPFTYVGYVPRF 4efc A 2.0 BS03 AMP B 1 R29 Y30 I320 N324 R18 Y19 I309 N313 H107 T184 H185 S311 K316 E323 H96 T173 H174 S300 K305 E312 4.3.2.2 0000166,0003824,0004018,0005654,0005737,0006164,0006188,0006189,0009152,0016829,0020015,0044208,0046872,0070626 Q38EJ2 501 VDYSVDNPLFALSPLDGRYKRQTKALRAFFSEYGFFRYRVLVEVEYFTALCKDVPTIVPLRSVTDEQLQKLRKITLDCFSVSSAEEIKRLERVTNHDIKAVEYFIKERMDTCGLSHVTEFVHFGLTSQDINNTAIPMMIRDAIVTLYLPALDGIIGSLTSKLVDWDVPMLARTHGQPASPTNLAKEFVVWIERLREQRRQLCEVPTTGKFGGATGNFNAHLVAYPSVNWRAFADMFLAKYLGLKRQQATTQIENYDHLAALCDACARLHVILIDMCRDVWQYISMGFFKQKVKEGEVGSSTMPHKVNPIDFENAEGNLALSNALLNFFASKLPISRLQRDLTDSTVLRNLGVPIGHACVAFASISQGLEKLMISRETISRELSSNWAVVAEGIQTVLRRECYPKPYETLKKLTVTEEQVRNFINGLTDISDDVRAELLAITPFTYVGYVPRF 4efc B 2.0 BS01 AMP A 1 R29 Y30 I320 N324 R18 Y19 I309 N313 H107 T184 H185 S311 K316 E323 H96 T173 H174 S300 K305 E312 4.3.2.2 0000166,0003824,0004018,0005654,0005737,0006164,0006188,0006189,0009152,0016829,0020015,0044208,0046872,0070626 Q38EJ2 501 VDYSVDNPLFALSPLDGRYKRQTKALRAFFSEYGFFRYRVLVEVEYFTALCKDVPTIVPLRSVTDEQLQKLRKITLDCFSVSSAEEIKRLERVTNHDIKAVEYFIKERMDTCGLSHVTEFVHFGLTSQDINNTAIPMMIRDAIVTLYLPALDGIIGSLTSKLVDWDVPMLARTHGQPASPTNLAKEFVVWIERLREQRRQLCEVPTTGKFGGATGNFNAHLVAYPSVNWRAFADMFLAKYLGLKRQQATTQIENYDHLAALCDACARLHVILIDMCRDVWQYISMGFFKQKVKEGEVGSSTMPHKVNPIDFENAEGNLALSNALLNFFASKLPISRLQRDLTDSTVLRNLGVPIGHACVAFASISQGLEKLMISRETISRELSSNWAVVAEGIQTVLRRECYPKPYETLKKVTEEQVRNFINGLTDISDDVRAELLAITPFTYVGYVPRF 4efc B 2.0 BS02 AMP B 1 N106 H107 D108 S138 Q139 R350 L352 S355 T356 R359 N95 H96 D97 S127 Q128 R339 L341 S344 T345 R348 H107 T184 H185 S311 K316 E323 H96 T173 H174 S300 K305 E312 4.3.2.2 0000166,0003824,0004018,0005654,0005737,0006164,0006188,0006189,0009152,0016829,0020015,0044208,0046872,0070626 Q38EJ2 501 VDYSVDNPLFALSPLDGRYKRQTKALRAFFSEYGFFRYRVLVEVEYFTALCKDVPTIVPLRSVTDEQLQKLRKITLDCFSVSSAEEIKRLERVTNHDIKAVEYFIKERMDTCGLSHVTEFVHFGLTSQDINNTAIPMMIRDAIVTLYLPALDGIIGSLTSKLVDWDVPMLARTHGQPASPTNLAKEFVVWIERLREQRRQLCEVPTTGKFGGATGNFNAHLVAYPSVNWRAFADMFLAKYLGLKRQQATTQIENYDHLAALCDACARLHVILIDMCRDVWQYISMGFFKQKVKEGEVGSSTMPHKVNPIDFENAEGNLALSNALLNFFASKLPISRLQRDLTDSTVLRNLGVPIGHACVAFASISQGLEKLMISRETISRELSSNWAVVAEGIQTVLRRECYPKPYETLKKVTEEQVRNFINGLTDISDDVRAELLAITPFTYVGYVPRF 4epm A 2.099 BS01 AMP A 1 S95 S96 V299 T301 T324 Y325 G326 S327 S328 Y347 D398 F414 S87 S88 V291 T293 T316 Y317 G318 S319 S320 Y339 D390 F406 6.3.2.- 0005515,0006952,0009626,0009863,0010112,0016046,0016874,0018874,0034052,0042742,0052625,0052626,0052627,0052628,0071456 Q9LYU4 22628555 601 ETFEKQLKDLTSNVKSIQDNLLEEIITPNTKTEYLQRFLIDRFDKELFKKNVPIVSYEDIKPYLDRVVNGESSDVISARTITGFLLSSGTSGGAQKMMPWNNKYLDNLTFIYDLRMQVITKHVKGVEEGKGMMFLFTKQESMTPSGLPARVATSSYFKSDYFKNRPSNWYYSYTSPDEVILCPNNTESLYCHLLCGLVQRDEVVRTGSIFASVMVRAIEVLKNSWEELCSNIRSGHLSNWVTDLGCQNSVSLVLGGPRPELADTIEEICNQNSWKGIVKRLWPNTKYIETVVTGSMGQYVPMLNYYCNDLPLVSTTYGSSETTFGINLDPLCKPEDVSYTFMPNMSYFEFIPMDGGDKNDVVDLEDVKLGCTYEPVVTNFAGLYRMRVGDIVLVTGFYNNAPQFKFVRRENVVLSIDSDKTNEEDLFKAVSQAKLVLESSGLDLKDFTSYADTSTFPGHYVVYLEVDTQFELDEEALSTCCLVMEESLDNVYKRCRFKDGSIGPLEIRVVRQGTFDSLMDFFISQGAYKTPRCIKSGKALQVLETCVVAKFFSI 4eq4 A 2.074 BS01 AMP A 1 S95 S96 V299 T301 T324 Y325 G326 S327 S328 Y347 D398 F414 K428 S88 S89 V292 T294 T317 Y318 G319 S320 S321 Y340 D391 F407 K421 6.3.2.- 0005515,0006952,0009626,0009863,0010112,0016046,0016874,0018874,0034052,0042742,0052625,0052626,0052627,0052628,0071456 Q9LYU4 22628555 602 NETFEKQLKDLTSNVKSIQDNLLEEIITPNTKTEYLQRFLIDRFDKELFKKNVPIVSYEDIKPYLDRVVNGESSDVISARTITGFLLSSGTSGGAQKMMPWNNKYLDNLTFIYDLRMQVITKHVKGVEEGKGMMFLFTKQESMTPSGLPARVATSSYFKSDYFKNRPSNWYYSYTSPDEVILCPNNTESLYCHLLCGLVQRDEVVRTGSIFASVMVRAIEVLKNSWEELCSNIRSGHLSNWVTDLGCQNSVSLVLGGPRPELADTIEEICNQNSWKGIVKRLWPNTKYIETVVTGSMGQYVPMLNYYCNDLPLVSTTYGSSETTFGINLDPLCKPEDVSYTFMPNMSYFEFIPMDGGDKNDVVDLEDVKLGCTYEPVVTNFAGLYRMRVGDIVLVTGFYNNAPQFKFVRRENVVLSIDSDKTNEEDLFKAVSQAKLVLESSGDFTSYADTSTFPGHYVVYLEVELDEEALSTCCLVMEESLDNVYKRCRFKDGSIGPLEIRVVRQGTFDSLMDFFISQYKTPRCIKSGKALQVLETCVVAKFFSI 4eq4 B 2.074 BS01 AMP B 1 S95 S96 V299 T301 S327 S328 Y347 D398 F414 R417 S87 S88 V291 T293 S319 S320 Y339 D390 F406 R409 6.3.2.- 0005515,0006952,0009626,0009863,0010112,0016046,0016874,0018874,0034052,0042742,0052625,0052626,0052627,0052628,0071456 Q9LYU4 22628555 602 ETFEKQLKDLTSNVKSIQDNLLEEIITPNTKTEYLQRFLIDRFDKELFKKNVPIVSYEDIKPYLDRVVNGESSDVISARTITGFLLSSGTSGGAQKMMPWNNKYLDNLTFIYDLRMQVITKHVKGVEEGKGMMFLFTKQESMTPSGLPARVATSSYFKSDYFKNRPSNWYYSYTSPDEVILCPNNTESLYCHLLCGLVQRDEVVRTGSIFASVMVRAIEVLKNSWEELCSNIRSGHLSNWVTDLGCQNSVSLVLGGPRPELADTIEEICNQNSWKGIVKRLWPNTKYIETVVTGSMGQYVPMLNYYCNDLPLVSTTYGSSETTFGINLDPLCKPEDVSYTFMPNMSYFEFIPMDGGDKNDVVDLEDVKLGCTYEPVVTNFAGLYRMRVGDIVLVTGFYNNAPQFKFVRRENVVLSIDSDKTNEEDLFKAVSQAKLVLESSGLDLKDFTSYADTSTFPGHYVVYLEVDTELDEEALSTCCLVMEESLDNVYKRCRFKDGSIGPLEIRVVTPRCIKSGKALQVLETCVVAKFF 4eq5 A 2.85 BS01 AMP A 1 L238 E259 K261 Y262 R266 R281 E311 F351 K415 R426 K432 L183 E204 K206 Y207 R211 R226 E256 F296 K360 R371 K377 6.5.1.6 0003677,0003909,0003910,0005524,0006260,0006266,0006273,0006281,0006310,0016874,0046872,0051301,0071897 C6A2U9 22297989 601 SLYKELVELYKRLEKTTLKTLKTKFVSDFLKSVEKPELLEVIPYLILGKVFPDWDERELGILLIKAVSTIERVYNTLVKIAEASGAGSQDRKLKYLANLFMDASPDEGKYLARTVLGIMRTGVAEGLLRDALADAFKVRVELVERAYMLTSDFGFVAKVAKLEGDEGLAKVKIQVGKPIKPMLAQMAANVREALVEMGGEAEFEIKYDGARVQVHKNGNKVLIYSRRLENVTKSIPEVVERVKEALKPEKVIVEGELVAVEETGRPRPFQYVLRRFRRKYNIEEMIEKIPLELNLFDILYVDGQNMIDTPFMERRKVLESVVNSNEWIKSAENLITKSPEEAEAFYHKALDLGHEGLMAKRLDSTYEPGNRGKKWLKIKPTMENLDLVVLGAEWGEGRRSGVLSSFLLGAYDPVKGDFVPVGKVGSGFTDEDLVEFTKMLKPLIKKEHGKEVELEPKVVIEVAYQEIQKSPKYESGFALRFPRYIALREDKGPEDADTVQRLAELYQFQERLKGGR 4eql A 1.8 BS01 AMP A 1 S95 S96 V299 T301 T324 Y325 G326 S327 S328 Y347 D398 F414 K428 S88 S89 V292 T294 T317 Y318 G319 S320 S321 Y340 D391 F407 K421 6.3.2.- 0005515,0006952,0009626,0009863,0010112,0016046,0016874,0018874,0034052,0042742,0052625,0052626,0052627,0052628,0071456 Q9LYU4 22628555 601 NETFEKQLKDLTSNVKSIQDNLLEEIITPNTKTEYLQRFLIDRFDKELFKKNVPIVSYEDIKPYLDRVVNGESSDVISARTITGFLLSSGTSGGAQKMMPWNNKYLDNLTFIYDLRMQVITKHVKGVEEGKGMMFLFTKQESMTPSGLPARVATSSYFKSDYFKNRPSNWYYSYTSPDEVILCPNNTESLYCHLLCGLVQRDEVVRTGSIFASVMVRAIEVLKNSWEELCSNIRSGHLSNWVTDLGCQNSVSLVLGGPRPELADTIEEICNQNSWKGIVKRLWPNTKYIETVVTGSMGQYVPMLNYYCNDLPLVSTTYGSSETTFGINLDPLCKPEDVSYTFMPNMSYFEFIPMDGGDKNDVVDLEDVKLGCTYEPVVTNFAGLYRMRVGDIVLVTGFYNNAPQFKFVRRENVVLSIDSDKTNEEDLFKAVSQATSYADTSTFPGHYVVYLELDEEALSTCCLVMEESLDNVYKRCRFKDGSIGPLEIRVKFFS 4eql B 1.8 BS01 AMP B 1 S95 S96 V299 T301 T324 Y325 G326 S327 S328 Y347 D398 F414 R417 S87 S88 V291 T293 T316 Y317 G318 S319 S320 Y339 D390 F406 R409 6.3.2.- 0005515,0006952,0009626,0009863,0010112,0016046,0016874,0018874,0034052,0042742,0052625,0052626,0052627,0052628,0071456 Q9LYU4 22628555 601 ETFEKQLKDLTSNVKSIQDNLLEEIITPNTKTEYLQRFLIDRFDKELFKKNVPIVSYEDIKPYLDRVVNGESSDVISARTITGFLLSSGTSGGAQKMMPWNNKYLDNLTFIYDLRMQVITKHVKGVEEGKGMMFLFTKQESMTPSGLPARVATSSYFKSDYFKNRPSNWYYSYTSPDEVILCPNNTESLYCHLLCGLVQRDEVVRTGSIFASVMVRAIEVLKNSWEELCSNIRSGHLSNWVTDLGCQNSVSLVLGGPRPELADTIEEICNQNSWKGIVKRLWPNTKYIETVVTGSMGQYVPMLNYYCNDLPLVSTTYGSSETTFGINLDPLCKPEDVSYTFMPNMSYFEFIPMDGGDKNDVVDLEDVKLGCTYEPVVTNFAGLYRMRVGDIVLVTGFYNNAPQFKFVRRENVVLSIDSDKTNEETSYADTSTFPGHYVVYLLSTCCLVMEESLDNVYKRCRFKDGSIGPLEIRAKFFSI 4eum A 1.8 BS01 AMP A 1 K223 G225 V242 A283 K229 G231 V248 A289 A253 A254 G255 D256 A259 A260 G261 D262 2.7.1.45 0005829,0006974,0008673,0016301,0016310,0016772,0019698,0042840,0046835,0046872 Q2CIP5 401 GVDLGTENLYFQSMMHILSIGECMAELAPADLPGTYRLGFAGDTFNTAWYLARLRPESRISYFSAIGDDALSQQMRAAMSAAGIDGGGLRVIPGRTVGLYLIFAYWRGQSAARELAGDADALAAAMARADVVYFSGITLAILDQCGRATLLRALAQARATGRTIAFDPNLRPRLWAGTGEMTETIMQGAAVSDIALPSFEDEAAWFGDAGPDATADRYARAGVRSVVVKNGPHAVHFLQDGRRGRVPVPPVAQVVDTTAAGDSFNAGLLDSVLAGQPLETAIAAAAALAGQVVQ 4eum B 1.8 BS01 AMP B 1 G225 P226 A280 A283 G236 P237 A289 A292 A253 A254 G255 D256 A262 A263 G264 D265 2.7.1.45 0005829,0006974,0008673,0016301,0016310,0016772,0019698,0042840,0046835,0046872 Q2CIP5 401 GVDLGTENLYFQSMMHILSIGECMAELAPADLPGTYRLGFAGDTFNTAWYLARLRPESRISYFSAIGDDALSQQMRAAMSAAGIDGGGLRVIPGRTVGLYLITLERSFAYWRGQSAARELAGDADALAAAMARADVVYFSGITLAILDQCGRATLLRALAQARATGRTIAFDPNLRPRLWAGTGEMTETIMQGAAVSDIALPSFEDEAAWFGDAGPDATADRYARAGVRSVVVKNGPHAVHFLQDGRRGRVPVPPVVVDTTAAGDSFNAGLLDSVLAGQPLETAIAAAAALAGQVVQGKGALVEV 4eys A 1.58 BS01 AMP A 1 E23 I78 G79 F108 S109 L132 A133 E171 F175 E252 H315 E23 I78 G79 F108 S109 L132 A133 E171 F175 E252 H315 ? 0000166,0016787 A0A0H2UN46 401 MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHSLKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQKIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRISEIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFDNSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVINGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQEQVILFDYNK 4fbc A 1.7 BS01 AMP A 1 Y87 L88 L170 R178 Y84 L85 L167 R175 3.2.2.22 0005737,0016787,0017148,0030598,0031640,0035821,0050832,0090729 P22244 23090398 301 KMAKNVDKPLFTATFNVQASSADYATFIAGIRNKLRNPAHFSHNRPVLPPVEPNVPPSRWFHVVLKASPTSAGLTLAIRADNIYLEGFKSSDGTWWELTPGLIPGATYVGFGGTYRDLLGDTDKLTNVALGRQQLADAVTALHGRTKADKPSGPKQQQAREAVTTLLLMVNEATRFQTVSGFVAGLLHPKAVAAASGKIGNEMKAQVNGWQDLSAALLKTDVKPPPGKSPAKFAPIEKMGVRTAVQAANTLGILLFVEVPGGLTVAKALELFHASGGK 4fbc B 1.7 BS01 AMP B 1 Y87 L88 L170 R178 Y84 L85 L167 R175 3.2.2.22 0005737,0016787,0017148,0030598,0031640,0035821,0050832,0090729 P22244 23090398 301 KMAKNVDKPLFTATFNVQASSADYATFIAGIRNKLRNPAHFSHNRPVLPPVEPNVPPSRWFHVVLKASPTSAGLTLAIRADNIYLEGFKSSDGTWWELTPGLIPGATYVGFGGTYRDLLGDTDKLTNVALGRQQLADAVTALHGRTKADKPSGPKQQQAREAVTTLLLMVNEATRFQTVSGFVAGLLHPKAVAAASGKIGNEMKAQVNGWQDLSAALLKTDVKPPPGKSPAKFAPIEKMGVRTAVQAANTLGILLFVEVPGGLTVAKALELFHASGGK 4fbc C 1.7 BS01 AMP C 1 Y87 L88 L170 R178 Y84 L85 L167 R175 3.2.2.22 0005737,0016787,0017148,0030598,0031640,0035821,0050832,0090729 P22244 23090398 301 KMAKNVDKPLFTATFNVQASSADYATFIAGIRNKLRNPAHFSHNRPVLPPVEPNVPPSRWFHVVLKASPTSAGLTLAIRADNIYLEGFKSSDGTWWELTPGLIPGATYVGFGGTYRDLLGDTDKLTNVALGRQQLADAVTALHGRTKADKPSGPKQQQAREAVTTLLLMVNEATRFQTVSGFVAGLLHPKAVAAASGKIGNEMKAQVNGWQDLSAALLKTDVKPPPGKSPAKFAPIEKMGVRTAVQAANTLGILLFVEVPGGLTVAKALELFHASGGK 4fbc D 1.7 BS01 AMP D 1 Y87 L88 G116 L170 R178 Y84 L85 G113 L167 R175 3.2.2.22 0005737,0016787,0017148,0030598,0031640,0035821,0050832,0090729 P22244 23090398 301 KMAKNVDKPLFTATFNVQASSADYATFIAGIRNKLRNPAHFSHNRPVLPPVEPNVPPSRWFHVVLKASPTSAGLTLAIRADNIYLEGFKSSDGTWWELTPGLIPGATYVGFGGTYRDLLGDTDKLTNVALGRQQLADAVTALHGRTKADKPSGPKQQQAREAVTTLLLMVNEATRFQTVSGFVAGLLHPKAVAAASGKIGNEMKAQVNGWQDLSAALLKTDVKPPPGKSPAKFAPIEKMGVRTAVQAANTLGILLFVEVPGGLTVAKALELFHASGGK 4fbh A 2.3 BS01 AMP A 1 Y87 L88 R178 Y84 L85 R175 3.2.2.22 0005737,0016787,0017148,0030598,0031640,0035821,0050832,0090729 P22244 23090398 301 KMAKNVDKPLFTATFNVQASSADYATFIAGIRNKLRNPAHFSHNRPVLPPVEPNVPPSRWFHVVLKASPTSAGLTLAIRADNIYLEGFKSSDGTWWELTPGLIPGATYVGFGGTYRDLLGDTDKLTNVALGRQQLADAVTALHGRTKADKPSGPKQQQAREAVTTLLLMVNEATRFQTVSGFVAGLLHPKSGKIGNEMKAQVNGWQDLSAALLKTDVKPPAKFAPIEKMGVRTAVQAANTLGILLFVEVPGGLTVAKALELFHASGGK 4fbp A 2.5 BS01 AMP A 1 G21 A24 T27 M30 K112 Y113 R140 M177 G13 A16 T19 M22 K94 Y95 R122 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 1850623 338 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4fbp B 2.5 BS01 AMP B 1 Q20 G21 A24 G26 T27 G28 E29 M30 K112 Y113 R140 M177 Q12 G13 A16 G18 T19 G20 E21 M22 K94 Y95 R122 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 1850623 338 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4fbp C 2.5 BS01 AMP D 1 Q20 G21 G26 T27 M30 K112 Y113 R140 V160 Q12 G13 G18 T19 M22 K94 Y95 R122 V142 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 1850623 338 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4fbp D 2.5 BS01 AMP C 1 Q20 G21 A24 T27 G28 E29 M30 T31 K112 Y113 M177 Q12 G13 A16 T19 G20 E21 M22 T23 K94 Y95 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 IC50=1300nM P00636 1850623 338 NIVTLTRFVMEQGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGKLDVLSNDLVINVLKSSFATCVLVTEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRNVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4ff4 A 2.026 BS02 AMP A 1 R424 G564 T674 Y678 D951 R419 G559 T669 Y673 D946 2.7.7.6 Q859P9 23235152 1201 EELKEGIDAVYPSLVGTADSKAEGIKNYFKLSFTLPEEQKSRTVGSEAPLKDVAQALSSRARYELFTEKETANPAFNGEVIKRYKELMEHGEGIADILRSRLAKFLNTKDVGKRFAQGTEANRWVGGKLLNIVEQDGDTFKYNEQLLQTAVLAGLQWRLTATSNTAIKDAKDVAAITGIDQALLPEGLVEQFDTGMTLTEAVSSLAQKIESYWGLSRNPNAPLGYTKGIPTAMAAEILAAFVESTDVVENIVDMSEIDPDNKKTIGLYTITELDSFDPINSFPTAIEEAVLVNPTEKMFFGDDIPPVANTQLRNPAVRNTPEQKAALKAEQATEFYVHTPMVQFYETLGKDRILELMGAGTLNKELLNDNHAKSLEGKNRSVEDSYNQLFSVIEQVRAQSEDISTVPIHYAYNMTRVGRMQMLGKYNPQSAKLVREAILPTKATLDLSNQNNEDFSAFQLGLAQALDIKVHTMTREVMSDELTKLLEGNLKPAIDMMVEFNTTGSLPENAVDVLNTALGDRKSFVALMALMEYSRYLVAEDKSAFVTPLYVEADGVTNGPINAMMLMTGGLFTPDWIRNIAKGGLFIGSPNKTMNEHRSTADNNDLYQASTNALMESLGKLRSNYASNMPIQSQIDSLLSLMDLFLPDINLGENGALELKRGIAKNPLTITIYGSGARGIAGKLVSSVTDAIYERMSDVLKARAKDPNISAAMAMFGKQAASEAHAEELLARFLKDMETLTSTVPVKRKGVLELQSTGTGAKGKINPKTYTIKGEQLKALQENMLHFFVEPLRNGITQTVGESLVYSTEQLQKATQIQSVVLEDMFKQRVQEKLAEKAKDPTWKKGDFLTQKELNDIQASLNNLAPMIETGSQTFYIAGSENAEVANQVLATNLDDRMRVPMSIYAPAQAGVAGIPFMTIGTGDGMMMQTLSTMKGAPKNTLKIFDGMNIGLNDITDASRKANEAVYTSWQGNPIKNVYESYAKFMKNVDFSKLSPEALEAIGKSALEYDQRENATVDDIANAASLIERNLRNIALGVDIRHKVLDKVNLSIDQMAAVGAPYQNNGKIDLSNMTPEQQADELNKLFREELEARKQ 4fry A 2.1 BS02 AMP A 1 I54 T56 D59 T81 V84 R85 M105 R106 H107 I52 T54 D57 T79 V82 R83 M103 R104 H105 ? 0000166 B1YXI0 23382856 202 TTVAQILKAKPDSGRTIYTVTKNDFVYDAIKLMAEKGIGALLVVDGDDIAGIVTERDYARKVVLQERSSKATRVEEIMTAKVRYVEPSQSTDECMALMTEHRMRHLPVLDGGKLIGLISIGDLVKSVIADQQFTIS 4fry B 2.1 BS03 AMP B 1 I54 T56 D59 T81 V84 R85 M105 R106 H107 I53 T55 D58 T80 V83 R84 M104 R105 H106 ? 0000166 B1YXI0 23382856 202 STTVAQILKAKPDSGRTIYTVTKNDFVYDAIKLMAEKGIGALLVVDGDDIAGIVTERDYARKVVLQERSSKATRVEEIMTAKVRYVEPSQSTDECMALMTEHRMRHLPVLDGGKLIGLISIGDLVKSVIADQQFTISQ 4fwk A 2.8 BS02 AMP A 1 G205 N206 D278 L279 R280 G326 I327 N330 G202 N203 D275 L276 R277 G323 I324 N327 N11 R86 H175 R236 E381 N8 R83 H172 R233 E378 2.7.2.15 0005524,0005829,0006082,0006083,0008776,0008980,0016301,0016310,0016774,0046872,0070689 O06961 23747922 502 FPVVLVINCGSSSIKFSVLDVATCDVLMAGIADGMNTENAFLSINGDKPINLAHSNYEDALKAIAFELEKRDLTDSVALIGHRIAHGGELFTQSVIITDEIIDNIRRVSPLAPLHNYANLSGIDAARHLFPAVRQVAVFDTSFHQTLAPEAYLYGLPWEYFSSLGVRRYGFHGTSHRYVSRRAYELLDLDEKDSGLIVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMAWIAKETGQTLSDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERARLAIKTFVHRIARHIAGHAASLHRLDGIIFTGGIGENSVLIRQLVIEHLGVLGLTLDVEMNKQPNSHGERIISANPSQVICAVIPTNEEKMIALDAIHLGNVKA 4g0y A 1.65 BS01 AMP A 1 N687 Y691 K695 Q707 C708 L710 K728 K732 N94 Y98 K102 Q114 C115 L117 K135 K139 ? 0003676 Kd=4.99mM -logKd/Ki=2.30, Kd=4.99mM O04379 22850669 801 SNKKMINGGTVNNWICINFSRQVQDNLARTFCQELAQMCYVSGMAFNPEPVLPPVSARPEQVEKVLKTRYHDATSKLSQGKEIDLLIVILPDNNGSLYGDLKRICETELGIVSQCCLTKHVFKMSKQYMANVALKINVKVGGRNTVL 4ga6 A 2.21 BS01 AMP A 1 H164 S165 I166 S194 A196 I197 T198 S199 T203 D256 M261 S264 K288 H164 S165 I166 S194 A196 I197 T198 S199 T203 D256 M261 S264 K288 D162 V163 H164 S165 T203 D243 A249 S264 K268 K269 D162 V163 H164 S165 T203 D243 A249 S264 K268 K269 2.4.2.57 0004645,0005829,0006196,0006206,0006213,0016208,0016757,0016763,0042301,0046125 Q5JCX3 23659790 601 MKAKIRILDMFSGRYTVLINEEDAKEAKLHPDDLVKIEAGKKAVYGSVALSNLVGKGEVGISRDVLDLHNFSEGETVSVIPAGTPESVRYIKKKMHGEKLRKVEIEAIVRDIVDRKLRDIEISSFVTALEINGLDMDEIAALTIAMAETGDMLDIDRKPIMDVHSIGGVPGNKTNILVVPIVAAAGLTIPKTSSRAITSAAGTADVVEVFADVSFSLDEIKRIVEKVGACLVWGGALNLAPADDITIKAERALSIDPTGLMLASIMSKKYAMGSQYVLIDIPTGKGVKVETVEEARSLARDFIELGKRLGQYVEVAITYGGQPIGHTVGPALEAREALSALMTGKGPGSLIEKATGLAGILLEMGGVAPAGTGKKMAKEILESGKAWEKMKEIIEAQGGDPNIKPEEIPIGDKTYTFTAATSGYVTAIDNRAITAIARAAGAPEDKGAGIELYVKVGEKVKEGDPLFTIHAEHEARLDQAIVLARRTEPIRIE 4ga6 B 2.21 BS01 AMP B 1 H164 S165 I166 S194 A196 I197 T198 S199 T203 D256 M261 S264 K288 H164 S165 I166 S194 A196 I197 T198 S199 T203 D256 M261 S264 K288 D162 V163 H164 S165 T203 D243 A249 S264 K268 K269 D162 V163 H164 S165 T203 D243 A249 S264 K268 K269 2.4.2.57 0004645,0005829,0006196,0006206,0006213,0016208,0016757,0016763,0042301,0046125 Q5JCX3 23659790 601 MKAKIRILDMFSGRYTVLINEEDAKEAKLHPDDLVKIEAGKKAVYGSVALSNLVGKGEVGISRDVLDLHNFSEGETVSVIPAGTPESVRYIKKKMHGEKLRKVEIEAIVRDIVDRKLRDIEISSFVTALEINGLDMDEIAALTIAMAETGDMLDIDRKPIMDVHSIGGVPGNKTNILVVPIVAAAGLTIPKTSSRAITSAAGTADVVEVFADVSFSLDEIKRIVEKVGACLVWGGALNLAPADDITIKAERALSIDPTGLMLASIMSKKYAMGSQYVLIDIPTGKGVKVETVEEARSLARDFIELGKRLGQYVEVAITYGGQPIGHTVGPALEAREALSALMTGKGPGSLIEKATGLAGILLEMGGVAPAGTGKKMAKEILESGKAWEKMKEIIEAQGGDPNIKPEEIPIGDKTYTFTAATSGYVTAIDNRAITAIARAAGAPEDKGAGIELYVKVGEKVKEGDPLFTIHAEHEARLDQAIVLARRTEPIRIE 4gbv A 2.9 BS04 AMP A 1 G21 T27 E29 M30 K112 Y113 R140 M177 G12 T18 E20 M21 K103 Y104 R131 M168 D68 D74 E97 E98 D118 L120 D121 E280 D59 D65 E88 E89 D109 L111 D112 E271 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 405 IVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGILHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4gbw A 2.0 BS05 AMP A 1 V17 E20 G21 A24 G26 T27 G28 E29 M30 K112 Y113 R140 M177 V8 E11 G12 A15 G17 T18 G19 E20 M21 K103 Y104 R131 M168 D68 D74 E97 E98 D118 L120 D121 E280 D59 D65 E88 E89 D109 L111 D112 E271 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 406 IVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGILHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4gqy A 2.193 BS01 AMP A 1 V125 S127 D130 T178 P181 L182 F202 R203 R204 V50 S52 D55 T93 P96 L97 F117 R118 R119 ? Q9C5D0 23664870 301 GYTVGDFMTPRQNLHVVKPSTSVDDALELLVEKKVTGLPVIDDNWTLVGVVSDYDLLALDSISGDVDSTWKTFNELQKLISKTYGKVVGDLMTPSPLVVRDSTNLEDAARLLLETKFRRLPVVDADGKLIGILTRGNVVRAALQIKR 4gqy B 2.193 BS01 AMP A 1 R203 R220 R106 R123 ? Q9C5D0 23664870 301 GYTVGDFMTPRQNLHVVKPSTSVDDALELLVEKKVTGLPVIDDNWTLVGVVSDYDLLALDFNELQKLISKTYGKVVGDLMTPSPLVVRDSTNLEDAARLLLETKFRRLPVVDADGKLIGILTRGNVVRAALQIKR 4gqy B 2.193 BS02 AMP B 1 S127 D130 T178 P181 L182 F202 R203 R204 S52 D55 T81 P84 L85 F105 R106 R107 ? Q9C5D0 23664870 301 GYTVGDFMTPRQNLHVVKPSTSVDDALELLVEKKVTGLPVIDDNWTLVGVVSDYDLLALDFNELQKLISKTYGKVVGDLMTPSPLVVRDSTNLEDAARLLLETKFRRLPVVDADGKLIGILTRGNVVRAALQIKR 4gqy C 2.193 BS01 AMP C 1 V125 S127 D130 T178 P181 L182 F202 R203 R204 V50 S52 D55 T92 P95 L96 F116 R117 R118 ? Q9C5D0 23664870 301 GYTVGDFMTPRQNLHVVKPSTSVDDALELLVEKKVTGLPVIDDNWTLVGVVSDYDLLALDSISGVDSTWKTFNELQKLISKTYGKVVGDLMTPSPLVVRDSTNLEDAARLLLETKFRRLPVVDADGKLIGILTRGNVVRAALQIKR 4gqy D 2.193 BS01 AMP D 1 S127 D130 T178 P181 L182 F202 R203 S52 D55 T80 P83 L84 F104 R105 ? Q9C5D0 23664870 301 GYTVGDFMTPRQNLHVVKPSTSVDDALELLVEKKVTGLPVIDDNWTLVGVVSDYDLLALDNELQKLISKTYGKVVGDLMTPSPLVVRDSTNLEDAARLLLETKFRRLPVVDADGKLIGILTRGNVVRAALQIKR 4gtw A 2.7 BS01 AMP A 1 T238 F239 N259 L272 K277 Y322 Y353 D358 H406 H517 T69 F70 N90 L103 K108 Y153 Y184 D189 H237 H348 3.1.4.1,3.1.4.39,3.6.1.9 0003676,0005044,0006955,0016787,0030247,0046872 P06802,Q9R1E6 23027977 1009 KSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDPEDDDIYHMTVPYGRPRILLKQHRVCLLQQQQFLTGYSLDLLMPLWASYTFLSNDSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNHIYSEALLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFS 4gtw B 2.7 BS01 AMP B 1 D200 T238 F239 N259 K277 Y322 Y353 D358 H406 H517 D31 T69 F70 N90 K108 Y153 Y184 D189 H237 H345 3.1.4.1,3.1.4.39,3.6.1.9 0003676,0005044,0006955,0016787,0030247,0046872 P06802,Q9R1E6 23027977 1005 KSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDPDDDIYHMTVPYGRPRILLKQHRVCLLQQQQFLTGYSLDLLMPLWASYTFLSNDNCLYQDLRIPLSPVHKCSYYKLSYGFLTPPRLNHIYSEALLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFS 4gvl A 3.0 BS02 AMP A 1 G360 R361 D381 R382 D397 T419 N420 R444 G251 R252 D272 R273 D288 T310 N311 R335 ? 0006813,0008324 Q74FS9 23240087 602 APWIERRLRYHPTIELPDDTRGHILIFGIDPITRTLIRKLESRNHLFVVVTDNYDQALHLEEQEGFKVVYGSPTDAHVLAGLRVAAARSIIANLSDPDNANLCLTVRSLCQTPIIAVVKEPVHGELLRLAGANQVVPLTRILGRYLGIRATTCGALAHILDSFGNLQIAELPVHGTPFAGKTIGESGIRQRTGLSIIGVWERGSLTTPQRETVLTEQSLLVLAGTKSQLAALEYLIGEAPEDELIFIIGHGRIGCAAAAFLDRKPVPFILIDRQESPVCNDHVVVYGDATVGQTLRQAGIDRASGIIVTTNDDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYAAGADFVVSNASVGANILGNLLEHKESAFLSEGMAVFRRPLPPAMAGKTIAETRLRPLTGCSIVAIEAPDRADILISPPPETILAEGARLILIGTSEQEKTFDQTIAAR 4gvl B 3.0 BS03 AMP B 1 G360 R361 D381 R382 D397 A398 T419 N420 R444 G251 R252 D272 R273 D288 A289 T310 N311 R335 ? 0006813,0008324 Q74FS9 23240087 602 APWIERRLRYHPTIELPDDTRGHILIFGIDPITRTLIRKLESRNHLFVVVTDNYDQALHLEEQEGFKVVYGSPTDAHVLAGLRVAAARSIIANLSDPDNANLCLTVRSLCQTPIIAVVKEPVHGELLRLAGANQVVPLTRILGRYLGIRATTCGALAHILDSFGNLQIAELPVHGTPFAGKTIGESGIRQRTGLSIIGVWERGSLTTPQRETVLTEQSLLVLAGTKSQLAALEYLIGEAPEDELIFIIGHGRIGCAAAAFLDRKPVPFILIDRQESPVCNDHVVVYGDATVGQTLRQAGIDRASGIIVTTNDDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYAAGADFVVSNASVGANILGNLLEHKESAFLSEGMAVFRRPLPPAMAGKTIAETRLRPLTGCSIVAIEAPDRADILISPPPETILAEGARLILIGTSEQEKTFDQTIAAR 4gvl C 3.0 BS03 AMP C 1 G360 R361 D381 R382 T419 N420 R444 G251 R252 D272 R273 T310 N311 R335 ? 0006813,0008324 Q74FS9 23240087 602 APWIERRLRYHPTIELPDDTRGHILIFGIDPITRTLIRKLESRNHLFVVVTDNYDQALHLEEQEGFKVVYGSPTDAHVLAGLRVAAARSIIANLSDPDNANLCLTVRSLCQTPIIAVVKEPVHGELLRLAGANQVVPLTRILGRYLGIRATTCGALAHILDSFGNLQIAELPVHGTPFAGKTIGESGIRQRTGLSIIGVWERGSLTTPQRETVLTEQSLLVLAGTKSQLAALEYLIGEAPEDELIFIIGHGRIGCAAAAFLDRKPVPFILIDRQESPVCNDHVVVYGDATVGQTLRQAGIDRASGIIVTTNDDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYAAGADFVVSNASVGANILGNLLEHKESAFLSEGMAVFRRPLPPAMAGKTIAETRLRPLTGCSIVAIEAPDRADILISPPPETILAEGARLILIGTSEQEKTFDQTIAAR 4gvl D 3.0 BS04 AMP D 1 G360 R361 D381 R382 D397 A398 T419 N420 R444 G251 R252 D272 R273 D288 A289 T310 N311 R335 ? 0006813,0008324 Q74FS9 23240087 602 APWIERRLRYHPTIELPDDTRGHILIFGIDPITRTLIRKLESRNHLFVVVTDNYDQALHLEEQEGFKVVYGSPTDAHVLAGLRVAAARSIIANLSDPDNANLCLTVRSLCQTPIIAVVKEPVHGELLRLAGANQVVPLTRILGRYLGIRATTCGALAHILDSFGNLQIAELPVHGTPFAGKTIGESGIRQRTGLSIIGVWERGSLTTPQRETVLTEQSLLVLAGTKSQLAALEYLIGEAPEDELIFIIGHGRIGCAAAAFLDRKPVPFILIDRQESPVCNDHVVVYGDATVGQTLRQAGIDRASGIIVTTNDDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYAAGADFVVSNASVGANILGNLLEHKESAFLSEGMAVFRRPLPPAMAGKTIAETRLRPLTGCSIVAIEAPDRADILISPPPETILAEGARLILIGTSEQEKTFDQTIAAR 4gws A 2.75 BS03 AMP A 1 E20 G21 A24 G26 T27 E29 M30 K112 Y113 R140 E12 G13 A16 G18 T19 E21 M22 K104 Y105 R132 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 403 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAIHRAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMYDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4gws B 2.75 BS03 AMP B 1 G21 A24 G26 T27 M30 K112 Y113 R140 M177 G13 A16 G18 T19 M22 K104 Y105 R132 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 403 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAIHRAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMYDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4gwy A 3.0 BS05 AMP A 1 V17 G21 A24 G26 T27 E29 M30 T31 K112 Y113 R140 M177 V8 G12 A15 G17 T18 E20 M21 T22 K103 Y104 R131 M168 D68 D74 E97 E98 D118 L120 D121 E280 D59 D65 E88 E89 D109 L111 D112 E271 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 406 IVTLTRFVKEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4gwz A 2.6 BS04 AMP A 1 E20 G21 A24 T27 E29 M30 K112 Y113 V160 M177 E12 G13 A16 T19 E21 M22 K104 Y105 V152 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 404 NIVTLTRFVWEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4gwz B 2.6 BS04 AMP B 1 G21 A24 G26 T27 E29 M30 T31 K112 Y113 R140 V160 M177 G13 A16 G18 T19 E21 M22 T23 K104 Y105 R132 V152 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 404 NIVTLTRFVWEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4gx4 A 2.5 BS04 AMP A 1 E20 G21 G26 T27 G28 E29 M30 Y113 M177 E12 G13 G18 T19 G20 E21 M22 Y105 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 404 NIVTLTRFVMEEGMKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4gx4 B 2.5 BS04 AMP B 1 E20 G21 A24 G26 T27 M30 K112 Y113 M177 E12 G13 A16 G18 T19 M22 K104 Y105 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 404 NIVTLTRFVMEEGMKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4gx6 A 2.5 BS04 AMP A 1 E20 G21 G26 T27 M30 K112 Y113 R140 M177 E12 G13 G18 T19 M22 K104 Y105 R132 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 404 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGQFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4gx6 B 2.5 BS04 AMP B 1 V17 E20 G21 A24 G26 T27 E29 M30 K112 Y113 R140 M177 V9 E12 G13 A16 G18 T19 E21 M22 K104 Y105 R132 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 404 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGQFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4h2s A 2.15 BS02 AMP A 1 R159 L169 F172 K235 A250 C251 S253 G283 R286 R142 L152 F155 K218 A233 C234 S236 G266 R269 C131 R159 E161 R168 E176 K235 A250 S253 C279 R286 C114 R142 E144 R151 E159 K218 A233 S236 C262 R269 6.2.1.n2 0000166,0004812,0005515,0005524,0006418,0016874,0046872 Q89VT8 23541895 1001 DPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSHREAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVCGLHGTEREINAAVSRFDAGGDWTTSLSPADLVLSPAACYPVYPIAASRGPLPKGGLRFDVAADCFRREPSKHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDYASDPFFGRVGQMKAVSQKQQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGEPAHTGCVAFGMDRLAVAMFHTHGTDLSAWPAKVRDILGL 4h2s B 2.15 BS02 AMP B 1 R159 L169 F172 K235 A250 C251 M252 S253 G283 R286 R143 L153 F156 K219 A234 C235 M236 S237 G267 R270 C131 R159 E161 R168 E176 K235 A250 S253 C279 R286 C115 R143 E145 R152 E160 K219 A234 S237 C263 R270 6.2.1.n2 0000166,0004812,0005515,0005524,0006418,0016874,0046872 Q89VT8 23541895 402 ADPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSHREAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVCGLHGTEREINAAVSRFDAGGDWTTSLSPADLVLSPAACYPVYPIAASRGPLPKGGLRFDVAADCFRREPSKHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDYASDPFFGRVGQMKAVSQKQQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGEPAHTGCVAFGMDRLAVAMFHTHGTDLSAWPAKVRDILGLQ 4h2v A 2.0 BS03 AMP A 1 R159 E161 L169 F172 K235 A250 C251 M252 S253 G283 R286 R142 E144 L152 F155 K218 A233 C234 M235 S236 G266 R269 C131 R159 E161 R168 E176 K235 A250 S253 C279 R286 C114 R142 E144 R151 E159 K218 A233 S236 C262 R269 6.2.1.n2 0000166,0004812,0005515,0005524,0006418,0016874,0046872 Q89VT8 23541895 402 DPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSHREAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVCGLHGTEREINAAVSRFDAGGDWTTSLSPADLVLSPAACYPVYPIAASRGPLPKGGLRFDVAADCFRREPSKHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDYASDPFFGRVGQMKAVSQKQQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGEPAHTGCVAFGMDRLAVAMFHTHGTDLSAWPAKVRDILGL 4h2v B 2.0 BS02 AMP B 1 R159 E161 L169 F172 M174 K235 A250 C251 S253 G283 R286 R143 E145 L153 F156 M158 K219 A234 C235 S237 G267 R270 C131 R159 E161 R168 E176 K235 A250 S253 C279 R286 C115 R143 E145 R152 E160 K219 A234 S237 C263 R270 6.2.1.n2 0000166,0004812,0005515,0005524,0006418,0016874,0046872 Q89VT8 23541895 402 ADPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSHREAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVCGLHGTEREINAAVSRFDAGGDWTTSLSPADLVLSPAACYPVYPIAASRGPLPKGGLRFDVAADCFRREPSKHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDYASDPFFGRVGQMKAVSQKQQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGEPAHTGCVAFGMDRLAVAMFHTHGTDLSAWPAKVRDILGLQ 4h2w B 1.95 BS02 AMP B 1 R159 L169 F172 K235 A250 C251 M252 S253 G283 R286 R143 L153 F156 K219 A234 C235 M236 S237 G267 R270 C131 R159 E161 R168 E176 K235 A250 S253 C279 R286 C115 R143 E145 R152 E160 K219 A234 S237 C263 R270 6.2.1.n2 0000166,0004812,0005515,0005524,0006418,0016874,0046872 Q89VT8 23541895 402 ADPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSHREAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVCGLHGTEREINAAVSRFDAGGDWTTSLSPADLVLSPAACYPVYPIAASRGPLPKGGLRFDVAADCFRREPSKHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDYASDPFFGRAGKMLANNQRDQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGEPAHTGCVAFGMDRLAVAMFHTHGTDLSAWPAKVRDILGL 4h46 A 2.5 BS03 AMP A 1 V17 E20 G21 A24 G26 T27 E29 M30 Y113 M177 V9 E12 G13 A16 G18 T19 E21 M22 Y97 M161 D74 E97 E98 D118 L120 D121 E280 D58 E81 E82 D102 L104 D105 E264 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 404 NIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4he2 A 1.6 BS01 AMP A 1 V17 K20 G21 A24 G26 T27 E29 L30 K112 Y113 T177 V7 K10 G11 A14 G16 T17 E19 L20 K85 Y86 T150 D74 E97 E98 D118 L120 D121 E280 D47 E70 E71 D91 L93 D94 E253 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 ic50=3.65uM O00757 24086250 401 LTLTRYVMEKGRQAKGTGELTRLLNSMLTAIKAISSAVRKAGLAKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTSEDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQ 4hg0 A 3.102 BS01 AMP A 1 I80 H100 S101 R102 F103 M165 E182 D183 I30 H50 S51 R52 F53 M115 E132 D133 ? 0005886,0050660 P0AE78 301 DEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 4hv4 A 2.25 BS01 AMP A 1 H128 G129 T131 T132 H292 N296 R327 D351 Y352 E358 T362 H110 G111 T113 T114 H274 N278 R309 D333 Y334 E340 T344 K130 T131 L155 E174 H199 K112 T113 L137 E156 H181 6.3.2.8 0005524,0005737,0008360,0008763,0009058,0009252,0016874,0016881,0051301,0071555 Q8ZIE8 501 VRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNSVTQHLTALGAQIYFHHRPENVLDASVVVVSTAISADNPEIVAAREARIPVIRRAEMLAELMRYRHGIAVAGTHGKTTTTAMLSSIYAEAGLDPTFVNGGLVKAAGTHARLGSSRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYGFSDDADVQIASYRQEGPQGHFTLRRQDKPLIEVTLNAPGRHNALNAAAAVAVATEEGIEDEDILRALVGFQGTGRRFDFLGNFPLAPVNGKEGSAMLVDDYGHHPTEVDATIKAARAGWPDKRIVMLFQPHRYTRTRDLYDDFANVLSQVDVLLMLDVYAAGEPPIPGADSRALCRTIRNRGKLDPILVPDSESAPEMLAQILNGEDLILVQGAGNIGKIARKLAEHKLQPQ 4hv4 B 2.25 BS01 AMP B 1 H128 G129 T131 T132 H292 N296 R327 D351 E358 T362 H114 G115 T117 T118 H271 N275 R306 D330 E337 T341 K130 T131 L155 E174 K116 T117 L141 E160 6.3.2.8 0005524,0005737,0008360,0008763,0009058,0009252,0016874,0016881,0051301,0071555 Q8ZIE8 501 EMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNSVTQHLTALGAQIYFHHRPENVLDASVVVVSTAISADNPEIVAAREARIPVIRRAEMLAELMRYRHGIAVAGTHGKTTTTAMLSSIYAEAGLDPTFVNGGLVKAAGTHARLGSSRYLIAEADESDASFLHLQPMVAIVTNIEADDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYGFSDDADVQIASYRQEGPQGHFTLRRQDKPLIEVTLNAPGRHNALNAAAAVAVATEEGIEDEDILRALVGFQGTGRRFDFLGNFPLAPVNGKEGSAMLVDDYGHHPTEVDATIKAARAGWPDKRIVMLFQPHRYTRTRDLYDDFANVLSQVDVLLMLDVYAAGEPPIPGADSRALCRTIRNRGKLDPILVPDSESAPEMLAQILNGEDLILVQGAGNIGKIARKLAEHKLQPQ 4hvj A 2.1 BS01 AMP A 1 D7 E9 F10 W47 H141 D8 E10 F11 W48 H138 3.1.13.- 0000287,0003676,0004527,0004532,0008408,0042802,0046872 P9WJ73 24311791 300 SMVRYFYDTEFIEDGHTIELISIGVVAEDGREYYAVSTEFDPERAGSWVRTHVLPKLPPPASQLWRSRQQIRLDLEEFLRIDGTDSIELWAWVGAYDHVALCQLWGPMTALPPTVPRFTRELRQLWEDRGCPRMPPVHDALVDARDQLRRFRLITS 4hxv A 2.6 BS02 AMP A 1 S198 S202 H203 D226 S227 R244 Y251 D257 S198 S202 H203 D226 S227 R244 Y251 D257 D46 E69 D118 I120 D121 T123 D257 D46 E69 D118 I120 D121 T123 D257 3.1.3.57,3.1.3.7 0000103,0000166,0000287,0004441,0005737,0006790,0008441,0016787,0016791,0046854,0046872 C4M4T9 25004978 402 MSFDKELALALEIVQVSCKITTSVAEHTLTDQTQIKNDKSPVTVGDYSVQAYVNKKIHETFPEDQIVAEEDTKTIPEDIFAKVCKHVQIYSDMKDDEIRKSIDLGNSTGGKGRHWVLDPIDGTLGFLRREQYAVCLAFMIDGDIKVGVLGCPNFEGGLIVAAQKGCGAKMFSVNDIKNGKDIHVSTTPKTSDMCFCESVEVSHTDQSRSKTITERLQVTKPPVRMDSQCKYMAIASGRADVYLRLPRNLSYQEKIWDHAAGYLIVKEAGGKVTDIYGNDLDFSLGRTLCNNHGIVASNGILHEETVNVVKDVLSDLK 4i5w A 2.793 BS02 AMP A 1 L50 N92 F94 V96 M165 T279 L286 K288 L50 N79 F81 V83 M145 T252 L259 K261 2.7.7.5,2.7.7.53 0003877,0004780,0005524,0005634,0005737,0008796,0009117,0009164,0009165,0016779,0016787,0033699 P22108 23628156 402 MIEENLKQKIHDKFVAAKKNGHLKVTHAESKKLKDPQTTTQYWVTFAPSLALDPFANPDEELVVTEDLNGDGEYKLLLNKFPVVPEHSLLVTSEFKDQRSALTPSDLMTAYNVLCSLQGCERYLVFYNCGPHSGSSQDHKHLQIMQMPEKFIPFQDVLCNGKDHFLPTFNAEPLQDDKVSFAHFVLPLPESSDQVDEDLLAMCYVSLMQRALTFFQDLTKSYNVLLTKKWICVVPRSHAKSGPPLMLNINSTGYCGMILVKDREKLENLTEDPHLVDKSLLQCGFPNTAGQK 4i5w A 2.793 BS03 AMP A 2 F68 N92 K93 S155 S156 H161 Q163 F55 N79 K80 S135 S136 H141 Q143 2.7.7.5,2.7.7.53 0003877,0004780,0005524,0005634,0005737,0008796,0009117,0009164,0009165,0016779,0016787,0033699 P22108 23628156 403 MIEENLKQKIHDKFVAAKKNGHLKVTHAESKKLKDPQTTTQYWVTFAPSLALDPFANPDEELVVTEDLNGDGEYKLLLNKFPVVPEHSLLVTSEFKDQRSALTPSDLMTAYNVLCSLQGCERYLVFYNCGPHSGSSQDHKHLQIMQMPEKFIPFQDVLCNGKDHFLPTFNAEPLQDDKVSFAHFVLPLPESSDQVDEDLLAMCYVSLMQRALTFFQDLTKSYNVLLTKKWICVVPRSHAKSGPPLMLNINSTGYCGMILVKDREKLENLTEDPHLVDKSLLQCGFPNTAGQK 4i5w B 2.793 BS01 AMP B 1 L75 N92 K93 F94 L102 S155 S156 H161 L60 N77 K78 F79 L87 S134 S135 H140 2.7.7.5,2.7.7.53 0003877,0004780,0005524,0005634,0005737,0008796,0009117,0009164,0009165,0016779,0016787,0033699 P22108 23628156 401 MIEENLKQKIHDKFVAAKKNGHLKVTHAESKKLKDPQTTTQYWVTFAPSLDPFANPDEELVVTEDLNGDGEYKLLLNKFPVVPEHSLLVTSEFKDQRSALTPSDLMTAYNVLCSLQGTCERYLVFYNCGPHSGSSQDHKHLQIMQMPEKFIPFQDVLCNGKDHAEPLQDDKVSFAHFVLPLPESSDQVDEDLLAMCYVSLMQRALTFFQELTKSYNVLLTKKWICVVPRSHAKSGPPLMLNINSTGYCGMILVKDREKLENLTEDPHLVDKSLLQCGFPNTA 4i5w B 2.793 BS02 AMP B 2 N92 F94 V96 V97 H100 M165 T279 N77 F79 V81 V82 H85 M144 T245 2.7.7.5,2.7.7.53 0003877,0004780,0005524,0005634,0005737,0008796,0009117,0009164,0009165,0016779,0016787,0033699 P22108 23628156 402 MIEENLKQKIHDKFVAAKKNGHLKVTHAESKKLKDPQTTTQYWVTFAPSLDPFANPDEELVVTEDLNGDGEYKLLLNKFPVVPEHSLLVTSEFKDQRSALTPSDLMTAYNVLCSLQGTCERYLVFYNCGPHSGSSQDHKHLQIMQMPEKFIPFQDVLCNGKDHAEPLQDDKVSFAHFVLPLPESSDQVDEDLLAMCYVSLMQRALTFFQELTKSYNVLLTKKWICVVPRSHAKSGPPLMLNINSTGYCGMILVKDREKLENLTEDPHLVDKSLLQCGFPNTA 4ifz A 1.9012 BS01 AMP A 1 F97 N98 L101 D159 G161 A162 S240 H256 I258 T288 F93 N94 L97 D155 G157 A158 S230 H246 I248 T278 2.7.1.180 0005886,0016740,0017013,0046872 O83774 23447540 501 ARVREYSRAELVIGTLCRVRVYSKRPAAEVHAALEEVFTLLQQQEMVLSANRDDSALAALNAQAGSAPVVVDRSLYALLERALFFAEKSGGAFNPALGAVVKLWNIGFDRAAVPDPDALKEALTRCDFRQVHLRAGVSVGAPHTVQLAQAGMQLDLGAIAKGFLADKIVQLLTAHALDSALVDLGGNIFALGLKYGAQRLEWNVGIRDPHGTGQKPALVVSVRDCSVVTSGAYERFFERDGVRYHHIIDPVTGFPAHTDVDSVSIFAPRSTDADALATACFVLGYEKSCALLREFPGVDALFIFPDKRVRASAGIVDRVRVLDARFVLER 4ig1 A 1.4318 BS01 AMP A 1 F97 N98 L101 D159 G161 A162 S240 H256 I258 T288 F91 N92 L95 D153 G155 A156 S228 H244 I246 T276 2.7.1.180 0005886,0016740,0017013,0046872 O83774 23447540 501 VREYSRAELVIGTLCRVRVYSKRPAAEVHAALEEVFTLLQQQEMVLSANRDDSALAALNAQAGSAPVVVDRSLYALLERALFFAEKSGGAFNPALGAVVKLWNIGFDRAAVPDPDALKEALTRCDFRQVHLRAGVSVGAPHTVQLAQAGMQLDLGAIAKGFLADKIVQLLTAHALDSALVDLGGNIFALGLKYGAQRLEWNVGIRDPHGTGQKPALVVSVRDCSVVTSGAYERFFERDGVRYHHIIDPVTGFPAHTDVDSVSIFAPRSTDADALATACFVLGYEKSCALLREFPGVDALFIFPDKRVRASAGIVDRVRVLDARFVLER 4ijn A 1.7 BS01 AMP A 1 G191 N192 D263 F264 R265 G311 V312 N315 V316 G191 N192 D263 F264 R265 G311 V312 N315 V316 N8 R72 H161 R222 E365 N8 R72 H161 R222 E365 2.7.2.1 0000287,0005524,0005737,0006082,0006083,0006085,0008776,0016301,0016310,0016774,0046872 A0QQK1 25613812 402 MVTVLVVNSGSSSLKYAVVRPASGEFLADGIIEEIGSGAVPDHDAALRAAFDELAAAGLHLEDLDLKAVGHRMVHGGKTFYKPSVVDDELIAKARELSPLAPLHNPPAIKGIEVARKLLPDLPHIAVFDTAFFHDLPAPASTYAIDRELAETWHIKRYGFHGTSHEYVSQQAAIFLDRPLESLNQIVLHLGNGASASAVAGGKAVDTSMGLTPMEGLVMGTRSGDIDPGVIMYLWRTAGMSVDDIESMLNRRSGVLGLGGASDFRKLRELIESGDEHAKLAYDVYIHRLRKYIGAYMAVLGRTDVISFTAGVGENVPPVRRDALAGLGGLGIEIDDALNSAKSDEPRLISTPDSRVTVLVVPTNEELAIARACVGV 4ijn B 1.7 BS01 AMP B 1 G191 N192 D263 F264 R265 A310 G311 V312 N315 V316 G190 N191 D262 F263 R264 A309 G310 V311 N314 V315 N8 R72 H161 R222 E365 N7 R71 H160 R221 E364 2.7.2.1 0000287,0005524,0005737,0006082,0006083,0006085,0008776,0016301,0016310,0016774,0046872 A0QQK1 25613812 402 VTVLVVNSGSSSLKYAVVRPASGEFLADGIIEEIGSGAVPDHDAALRAAFDELAAAGLHLEDLDLKAVGHRMVHGGKTFYKPSVVDDELIAKARELSPLAPLHNPPAIKGIEVARKLLPDLPHIAVFDTAFFHDLPAPASTYAIDRELAETWHIKRYGFHGTSHEYVSQQAAIFLDRPLESLNQIVLHLGNGASASAVAGGKAVDTSMGLTPMEGLVMGTRSGDIDPGVIMYLWRTAGMSVDDIESMLNRRSGVLGLGGASDFRKLRELIESGDEHAKLAYDVYIHRLRKYIGAYMAVLGRTDVISFTAGVGENVPPVRRDALAGLGGLGIEIDDALNSAKSDEPRLISTPDSRVTVLVVPTNEELAIARACVGV 4ike A 1.48 BS01 AMP A 1 T31 L35 R36 M53 E57 L58 V59 I64 R85 Q89 T31 L35 R36 M53 E57 L58 V59 I64 R85 Q89 K13 R85 R124 R150 R161 K13 R85 R124 R150 R161 2.7.4.3 0004017,0004550,0005524,0005737,0005829,0006139,0009123,0009132,0009165,0016301,0016310,0016776,0019205,0043231,0044209,0046940,0050145 O66490 301 MILVFLGPPGAGKGTQAKRLAKEKGFVHISTGDILREAVQKGTPLGKKAKEYMERGELVPDDLIIALIEEVFPKHGNVIFDGFPRTVKQAEALDEMLEKKGLKVDHVLLFEVPDEVVIERLSGRRINPETGEVYHVKYNPPPPGVKVIQREDDKPEVIKKRLEVYREQTAPLIEYYKKKGILRIIDASKPVEEVYRQVLEVIGDGN 4ike B 1.48 BS01 AMP B 1 T31 G32 L35 R36 M53 E57 L58 V59 I64 G82 R85 Q89 T31 G32 L35 R36 M53 E57 L58 V59 I64 G82 R85 Q89 K13 R85 R124 R150 R161 K13 R85 R124 R150 R161 2.7.4.3 0004017,0004550,0005524,0005737,0005829,0006139,0009123,0009132,0009165,0016301,0016310,0016776,0019205,0043231,0044209,0046940,0050145 O66490 301 MILVFLGPPGAGKGTQAKRLAKEKGFVHISTGDILREAVQKGTPLGKKAKEYMERGELVPDDLIIALIEEVFPKHGNVIFDGFPRTVKQAEALDEMLEKKGLKVDHVLLFEVPDEVVIERLSGRRINPETGEVYHVKYNPPPPGVKVIQREDDKPEVIKKRLEVYREQTAPLIEYYKKKGILRIIDASKPVEEVYRQVLEVIGDGN 4imy A 2.94 BS01 AMP A 1 A46 K48 E66 L70 V79 F103 D104 F105 C106 L156 A166 D167 F168 A39 K41 E59 L63 V72 F88 D89 F90 C91 L141 A151 D152 F153 D149 K151 A153 N154 D167 S180 T191 D134 K136 A138 N139 D152 S165 T176 2.7.11.22,2.7.11.23 0004672,0005524,0006468 P50750 23471103 401 VECPFCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKGMLST 4imy C 2.94 BS01 AMP C 1 A46 K48 F103 D104 C106 D167 A35 K37 F84 D85 C87 D148 D149 K151 A153 N154 D167 S180 T191 D130 K132 A134 N135 D148 S161 T172 2.7.11.22,2.7.11.23 0004672,0005524,0006468 P50750 23471103 401 VECPFCDEVSKYEKLAKIGGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKGMLST 4imy E 2.94 BS01 AMP E 1 A46 K48 E66 F103 D104 F105 C106 L156 D167 A39 K41 E59 F87 D88 F89 C90 L140 D151 D149 K151 A153 N154 D167 S180 T191 D133 K135 A137 N138 D151 S164 T175 2.7.11.22,2.7.11.23 0004672,0005524,0006468 P50750 23471103 401 VECPFCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKGMLST 4ini A 1.65 BS01 AMP A 1 S63 D80 V81 N136 S144 V145 H151 S2 D19 V20 N75 S83 V84 H90 3.9.1.- 0003824 Q9BX68 23659632 201 KSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKPIPRISQAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVINDGKLGAQSVYHLHIHVLGGRQLQWPPG 4ini B 1.65 BS01 AMP B 1 D80 V81 N136 S144 V145 H149 H151 D29 V30 N85 S93 V94 H98 H100 3.9.1.- 0003824 Q9BX68 23659632 201 APTIFSRILDKSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKPIPRISQAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVINDGKLGAQSVYHLHIHVLGGRQLQWPPG 4itr A 2.3 BS01 AMP D 1 A3673 G3722 N3723 G3724 R3728 I3755 Q3757 A186 G235 N236 G237 R241 I268 Q270 2.7.7.108,3.4.22.- Q06277 20622875 201 VNYQDLEDNLNLKGLISLEDDRNANFESNVLKNEKFLDEAREISKKSIPEATVKQMSHLPEFDDILTEGAKKVESRINKAITFRPSVEEFSEIQDLVKTLPKTKVIEDLSTKTNEITEALAATSKTIQRTPELKEQLKTAIEDFLQNSQGKPLTVQMIENLNHGLRPDEGEGRLLYKKENLTKENAVFSSPEAAKIQLAETVDFINRAKNEGIEPSVVGALVYQRLIAYAPFAEGNGRMARVIVNKILLDAGYPAFTKFSDEFEPQIIPQTKASTKSATSSEVVVEFLKELAKKGSKED 4itr B 2.3 BS01 AMP C 1 E3671 A3673 I3714 N3723 G3724 R3728 I3755 Q3757 E184 A186 I227 N236 G237 R241 I268 Q270 2.7.7.108,3.4.22.- Q06277 20622875 201 VNYQDLEDNLNLKGLISLEDDRNANFESNVLKNEKFLDEAREISKKSIPEATVKQMSHLPEFDDILTEGAKKVESRINKAITFRPSVEEFSEIQDLVKTLPKTKVIEDLSTKTNEITEALAATSKTIQRTPELKEQLKTAIEDFLQNSQGKPLTVQMIENLNHGLRPDEGEGRLLYKKENLTKENAVFSSPEAAKIQLAETVDFINRAKNEGIEPSVVGALVYQRLIAYAPFAEGNGRMARVIVNKILLDAGYPAFTKFSDEFEPQIIPQTKASTKSATSSEVVVEFLKELAKKGS 4jzk A 1.63 BS02 AMP A 1 T31 G32 L35 R36 M53 K57 L58 V59 V64 R88 Q92 R156 T31 G32 L35 R36 M53 K57 L58 V59 V64 R88 Q92 R156 0004017,0005524,0006139,0016776,0019205 302 MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG 4jzk B 1.63 BS02 AMP B 1 T31 G32 L35 R36 M53 K57 V59 V64 R88 Q92 R156 T31 G32 L35 R36 M53 K57 V59 V64 R88 Q92 R156 0004017,0005524,0006139,0016776,0019205 302 MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG 4k46 A 2.01 BS02 AMP A 1 T31 G32 L35 R36 I53 Q57 V59 I64 R88 Q92 T31 G32 L35 R36 I53 Q57 V59 I64 R88 Q92 K13 R88 R123 R156 R167 K13 R88 R123 R156 R167 2.7.4.3 0004017,0004550,0005524,0005737,0005829,0006139,0009123,0009132,0009165,0016301,0016310,0016776,0019205,0044209,0046940,0050145 Q6LTE1 302 MRIILLGAPGAGKGTQAQFIMAKFGIPQISTGDMLRAAIKAGTELGKQAKSVIDAGQLVSDDIILGLVKERIAQDDCAKGFLLDGFPRTIPQADGLKEVGVVVDYVIEFDVADSVIVERMAGRRAHLASGRTYHNVYNPPKVEGKDDVTGEDLVIREDDKEETVLARLGVYHNQTAPLIAYYGKEAEAGNTQYLKFDGTKAVAEVSAELEKALA 4kbf A 1.9 BS01 AMP A 1 F3 L21 T23 Q28 G48 G50 K51 T52 F3 L21 T23 Q28 G48 G50 K51 T52 ? 0003676,0003724,0005524 Q72GF3 23765433 401 MEFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAERLAPSQERGRKPRALVLTPTRELALQVASELTAVAPHLKVVAVYGGTGYGKQKEALLRGADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQTLLFSATLPSWAKRLAERYMKNPVLINVIKDEPVTYEEEAVPAPVRGRLEVLSDLLYVASPDRAMVFTRTKAETEEIAQGLLRLGHPAQALHGDLSQGERERVLGAFRQGEVRVLVATDVAARGLDIPQVDLVVHYRLPDRAEAYQHRSGRTGRAGRGGRVVLLYGPRERRDVEALERAVGRRFKRVN 4kfs A 1.946 BS01 AMP A 1 K14 S15 G16 K17 S18 Y19 Y186 K14 S15 G16 K17 S18 Y19 Y183 3.-.-.- 0000166,0046872 D5IEZ9 23698307 301 MNPDDIVVLVGRKKSGKSYLIKHYFIPVLKAHKISYIIDDHNLSGSEYSKFGYNATSLSDIVSKQYVVVYDRANDDFFEKLWQASKLHSKKYGTTVLIIDEAYYHFKYKQKVTPAIDEALHANRHAGLGLILSTQRVYDLMPIVYKQADLIIMFYTREPNELRWISKYISAEAAEKVKTLKQYHFLIYDVNSQTIKIHKPIL 4kke A 2.2 BS01 AMP A 1 I70 S72 V78 A91 K93 M149 N152 S193 L206 I26 S28 V34 A47 K49 M105 N108 S149 L162 D189 K191 N194 D207 T226 D145 K147 N150 D163 T180 2.7.11.24 0004672,0004707,0005524,0006468 P53779 501 DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTASFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMN 4kr2 A 3.292 BS02 AMP A 1 R277 I287 V289 F292 E403 I404 G526 R133 I143 V145 F148 E252 I253 G308 2.7.7.-,6.1.1.14 0000166,0004812,0004820,0005524,0005737,0006418,0006426 P41250 24898252 701 IVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMECDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQE 4kxp A 2.7 BS04 AMP A 1 E20 G21 A24 G26 T27 M30 T31 Y113 M177 E11 G12 A15 G17 T18 M21 T22 Y87 M151 D74 E97 E98 D118 L120 D121 E280 D48 E71 E72 D92 L94 D95 E254 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 23844654 405 DVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHA 4kxp B 2.7 BS04 AMP B 1 G21 A24 G26 T27 M30 K112 Y113 R140 M177 G12 A15 G17 T18 M21 K86 Y87 R114 M151 D74 E97 E98 D118 L120 D121 E280 D48 E71 E72 D92 L94 D95 E254 3.1.3.11 0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0071286,0071466 P00636 23844654 405 DVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK 4li4 A 1.71 BS01 AMP A 1 F57 P61 Y62 Y63 S64 F66 S67 G68 Y124 R164 A171 E189 F2 P6 Y7 Y8 S9 F11 S12 G13 Y66 R106 A113 E131 ? 0003723,0019013 P33469 24564608 201 EFNVVPYYSWFSGITQFQKGKEFEFVEGQGVPIAPGVPATEAKGYWYRHNRRSFKTADGQLLPRWYFYYLGTGPHAKDQYGTDIDGVYWVASNQADVNTPADIVDRDPSSDEAIPTRFPPGTVLPQGYYIEGS 4lqy A 1.54 BS01 AMP A 1 D34 T70 F71 N91 D104 Y154 Y184 D189 H336 D11 T47 F48 N68 D81 Y131 Y161 D166 H313 3.6.1.29 ic50=129uM -logKd/Ki=3.89, IC50=129uM Q9Y6X5 24338010 505 LPPKLLLVSFDGFRADYLKNYEFPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKHFSDSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDVPIHDTISSYFMNYNSSVSFEERLNNITMWLNNSNPPVTFATLYWEEPDASGHKYGPEDKENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYYTLIDLSPVAAILPKINRTEVYNKLKNCSPHMNVYLKEDIPNRFYYQHNDRIQPIILVADEGWTIVLNESSQKLGDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINIVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCI 4m0k A 1.4 BS01 AMP A 1 Q25 F26 K27 D124 V126 A128 T129 G130 T132 Q21 F22 K23 D120 V122 A124 T125 G126 T128 R64 E101 L121 A128 R60 E97 L117 A124 2.4.2.7 0000166,0002055,0003999,0005737,0006166,0006168,0016208,0016757,0044209,0046872 D0MGF4 300 ALETLKQAIRTVPDFPEPGIQFKDITPVLGHPELLRLAIEALLEPFQEQEITKVVGIESRGFILGGMLAHHLDAGFVPVRKKGKLPYQTLAESYQLEYGTDTIEMHIDAIEPGDRVLIHDDVIATGGTAEATIRLVERAGGEVVGCAFLIELTGLQGRKRLPAHVPVHTVLQL 4m0k B 1.4 BS01 AMP B 1 Q25 F26 K27 D124 V126 A128 T129 G130 T132 Q22 F23 K24 D121 V123 A125 T126 G127 T129 R64 E101 L121 A128 R61 E98 L118 A125 2.4.2.7 0000166,0002055,0003999,0005737,0006166,0006168,0016208,0016757,0044209,0046872 D0MGF4 300 TALETLKQAIRTVPDFPEPGIQFKDITPVLGHPELLRLAIEALLEPFQEQEITKVVGIESRGFILGGMLAHHLDAGFVPVRKKGKLPYQTLAESYQLEYGTDTIEMHIDAIEPGDRVLIHDDVIATGGTAEATIRLVERAGGEVVGCAFLIELTGLQGRKRLPAHVPVHTVLQL 4m0k C 1.4 BS01 AMP C 1 F26 K27 D124 V126 A128 T129 G130 T132 F25 K26 D123 V125 A127 T128 G129 T131 R64 E101 L121 A128 R63 E100 L120 A127 2.4.2.7 0000166,0002055,0003999,0005737,0006166,0006168,0016208,0016757,0044209,0046872 D0MGF4 201 NATALETLKQAIRTVPDFPEPGIQFKDITPVLGHPELLRLAIEALLEPFQEQEITKVVGIESRGFILGGMLAHHLDAGFVPVRKKGKLPYQTLAESYQLEYGTDTIEMHIDAIEPGDRVLIHDDVIATGGTAEATIRLVERAGGEVVGCAFLIELTGLQGRKRLPAHVPVHTVLQL 4m0k D 1.4 BS01 AMP D 1 Q25 F26 K27 D124 V126 A128 T129 G130 T132 Q24 F25 K26 D123 V125 A127 T128 G129 T131 R64 E101 L121 A128 R63 E100 L120 A127 2.4.2.7 0000166,0002055,0003999,0005737,0006166,0006168,0016208,0016757,0044209,0046872 D0MGF4 300 NATALETLKQAIRTVPDFPEPGIQFKDITPVLGHPELLRLAIEALLEPFQEQEITKVVGIESRGFILGGMLAHHLDAGFVPVRKKGKLPYQTLAESYQLEYGTDTIEMHIDAIEPGDRVLIHDDVIATGGTAEATIRLVERAGGEVVGCAFLIELTGLQGRKRLPAHVPVHTVLQL 4m9d A 1.821 BS01 AMP A 1 N38 G126 T127 T128 Q223 L227 V237 T238 V272 G273 N38 G126 T127 T128 Q223 L227 V237 T238 V272 G273 D13 K16 G40 H41 Q223 D13 K16 G40 H41 Q223 6.3.4.4 0000166,0000287,0004019,0005525,0005737,0006164,0016874,0044208,0046040,0046872 Q81JI9 501 MSSVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEELKYLHDRGVSTDNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLEQNLAQKNRLFEKMYDTEGFSVDEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSSNPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVSGLTDLSLNSIDVLTGIPTLKICVAYKCDGKVIDEVPANLNILAKCEPVCEELPGWTEDITGVRSLDELPENARKYVERVSELTGIQLSMFSVGPDRNQTNIV 4m9d B 1.821 BS01 AMP B 1 N38 T127 T128 Q223 L227 V237 T238 V272 G273 N41 T130 T131 Q226 L230 V240 T241 V275 G276 D13 K16 G40 H41 Q223 D16 K19 G43 H44 Q226 6.3.4.4 0000166,0000287,0004019,0005525,0005737,0006164,0016874,0044208,0046040,0046872 Q81JI9 501 SNAMSSVVVVGTQWGDEGKGKITDFLSEHAEVVARYQGGNNAGHTIVFGGVKYKLHLIPSGIFYKEKICVIGNGLVVDPKALLEELKYLHDRGVSTDNLRVSNRAHVILPYHLKQDELEEASKGDNKIGTTKKGIGPAYMDKAARIGIRMADLLDREAFKEKLEQNLAQKNRLFEKMYDTEGFSVDEIFEEYFEYGQQIAQYVCDTSVVLNDALDNNHRVLFEGAQGVMLDIDHGTYPFVTSSNPIAGGVTVGTGVGPAKVTRVVGVCKAYTSRVGDGPFPTELHDEIGHQIREVGREYGTTTGRPRRVGWFDSVVVRHARRVSGLTDLSLNSIDVLTGIPTLKICVAYKCDGKVIDEVPANLNILAKCEPVCEELPGWTEDITGVRSLDELPENARKYVERVSELTGIQLSMFSVGPDRNQTNIVRNVYE 4ma0 A 1.982 BS01 AMP A 1 I136 K138 E175 A176 F177 V178 E183 H206 F249 E259 I136 K138 E175 A176 F177 V178 E183 H206 F249 E259 Y144 G146 E247 E259 N266 S267 K335 Y144 G146 E247 E259 N266 S267 K335 6.3.4.18 0004638,0005524,0006164,0006189,0016829,0016874,0034028,0046872 Q5NGE8 401 MKIGIIGAGQLARMLSLAGTPLGLEFHCLGKNGDCAEEVVKTVTDIELTKVNDVVAWAKQFDVITFENENISHELIKAINHEVSVYPSAKAIAISQDRLLEKSFMQDHGIATAKFVNIDSLAKLQSAVDDHGLPAILKTRRFGYDGKGQFVIRSQEDITKAWDVLKDAPDGLIYEAFVDFDYEVSQICTADLKGNIAFYPLARNTHKQGIIVESEAPFENVVLAEKAQQIAKILVKEFAYVGTLAIEFFVKGDELIVNEIAPRVHNSGHWSIDGAVTSQFENHVRAIAGLILGDTTSRKTVMLNCIGGMPATKDLAALDRVKIHSYNKEPRKGRKVGHLNLNLNDETDEYQLLQVKKLIALSEEIA 4mpo A 1.9 BS01 AMP A 1 H38 K43 Y80 F82 K92 F129 H35 K40 Y77 F79 K89 F126 3.-.-.- 0000166,0004081,0006167,0006754,0016787,0046872 A0A0H3MCJ9 24354275 202 TKHEYSFGVIPIRFFGTPDRSTLKACFICHTDGKHWGFPKGHAEEKEGPQEAAERELVEETGLGIVNFFPKIFVENYSFNDKEEIFVRKEVTYFLAEVKGEVHADPDEICDVQWLSFQEGLRLLNFPEIRNIVTEADKFVQSYLF 4mpo B 1.9 BS01 AMP B 1 H38 K43 Y80 F82 K92 F129 E131 H38 K43 Y80 F82 K92 F129 E131 3.-.-.- 0000166,0004081,0006167,0006754,0016787,0046872 A0A0H3MCJ9 24354275 202 MMKTKHEYSFGVIPIRFFGTPDRSTLKACFICHTDGKHWGFPKGHAEEKEGPQEAAERELVEETGLGIVNFFPKIFVENYSFNDKEEIFVRKEVTYFLAEVKGEVHADPDEICDVQWLSFQEGLRLLNFPEIRNIVTEADKFVQSYLF 4mpo C 1.9 BS03 AMP C 1 H38 K43 Y80 F82 K92 F129 H35 K40 Y77 F79 K89 F126 3.-.-.- 0000166,0004081,0006167,0006754,0016787,0046872 A0A0H3MCJ9 24354275 204 TKHEYSFGVIPIRFFGTPDRSTLKACFICHTDGKHWGFPKGHAEEKEGPQEAAERELVEETGLGIVNFFPKIFVENYSFNDKEEIFVRKEVTYFLAEVKGEVHADPDEICDVQWLSFQEGLRLLNFPEIRNIVTEADKFVQSYLF 4mpo D 1.9 BS01 AMP D 1 H38 K43 Y80 F82 K92 F129 H35 K40 Y77 F79 K89 F126 3.-.-.- 0000166,0004081,0006167,0006754,0016787,0046872 A0A0H3MCJ9 24354275 202 TKHEYSFGVIPIRFFGTPDRSTLKACFICHTDGKHWGFPKGHAEEKEGPQEAAERELVEETGLGIVNFFPKIFVENYSFNDKEEIFVRKEVTYFLAEVKGEVHADPDEICDVQWLSFQEGLRLLNFPEIRNIVTEADKFVQSYLF 4mpo E 1.9 BS03 AMP E 1 H38 K43 Y80 F82 K92 F129 H34 K39 Y76 F78 K88 F125 3.-.-.- 0000166,0004081,0006167,0006754,0016787,0046872 A0A0H3MCJ9 24354275 204 KHEYSFGVIPIRFFGTPDRSTLKACFICHTDGKHWGFPKGHAEEKEGPQEAAERELVEETGLGIVNFFPKIFVENYSFNDKEEIFVRKEVTYFLAEVKGEVHADPDEICDVQWLSFQEGLRLLNFPEIRNIVTEADKFVQSYLF 4mpo F 1.9 BS01 AMP F 1 H38 K43 Y80 F82 K92 F129 E131 H34 K39 Y76 F78 K88 F125 E127 3.-.-.- 0000166,0004081,0006167,0006754,0016787,0046872 A0A0H3MCJ9 24354275 201 KHEYSFGVIPIRFFGTPDRSTLKACFICHTDGKHWGFPKGHAEEKEGPQEAAERELVEETGLGIVNFFPKIFVENYSFNDKEEIFVRKEVTYFLAEVKGEVHADPDEICDVQWLSFQEGLRLLNFPEIRNIVTEADKFVQSY 4mpo G 1.9 BS01 AMP G 1 H38 K43 Y80 F82 K92 F129 H31 K36 Y73 F75 K80 F117 3.-.-.- 0000166,0004081,0006167,0006754,0016787,0046872 A0A0H3MCJ9 24354275 201 KHEYSFGVIPIRFFDRSTLKACFICHTDGKHWGFPKGHAEEKEGPQEAAERELVEETGLGIVNFFPKIFVENYSFNFVRKEVTYFLAEVKGEVHADPDEICDVQWLSFQEGLRLLNFPEIRNIVTEADKFVQSYLF 4mpo H 1.9 BS01 AMP H 1 H38 K43 Y80 F82 K92 F129 E131 H34 K39 Y76 F78 K88 F125 E127 3.-.-.- 0000166,0004081,0006167,0006754,0016787,0046872 A0A0H3MCJ9 24354275 201 KHEYSFGVIPIRFFGTPDRSTLKACFICHTDGKHWGFPKGHAEEKEGPQEAAERELVEETGLGIVNFFPKIFVENYSFNDKEEIFVRKEVTYFLAEVKGEVHADPDEICDVQWLSFQEGLRLLNFPEIRNIVTEADKFVQSYLF 4mx2 A 1.9 BS01 AMP A 1 N117 H118 D119 S149 R361 L363 S366 T367 R370 N94 H95 D96 S126 R329 L331 S334 T335 R338 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQITEEVRQELLAITPFTYVGYT 4mx2 A 1.9 BS02 AMP B 1 R40 Y41 N335 R17 Y18 N303 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQITEEVRQELLAITPFTYVGYT 4mx2 B 1.9 BS01 AMP A 1 R40 Y41 I331 N335 R17 Y18 I299 N303 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKPYEALKDHVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 B 1.9 BS02 AMP B 1 N117 H118 D119 S149 R361 L363 S366 T367 R370 N94 H95 D96 S126 R329 L331 S334 T335 R338 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKPYEALKDHVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 C 1.9 BS01 AMP C 1 N117 H118 D119 S149 R361 L363 S366 T367 R370 N94 H95 D96 S126 R329 L331 S334 T335 R338 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTA 4mx2 C 1.9 BS02 AMP D 1 R40 Y41 I331 N335 R17 Y18 I299 N303 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTA 4mx2 D 1.9 BS01 AMP C 1 R40 Y41 I331 N335 R17 Y18 I301 N305 H118 T195 H196 E334 H95 T172 H173 E304 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVRAGEVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKPYEALKVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 D 1.9 BS02 AMP D 1 N117 H118 D119 R361 L363 S366 T367 R370 N94 H95 D96 R331 L333 S336 T337 R340 H118 T195 H196 E334 H95 T172 H173 E304 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVRAGEVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKPYEALKVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 E 1.9 BS01 AMP E 1 N117 H118 D119 S149 R361 L363 S366 T367 R370 N94 H95 D96 S126 R329 L331 S334 T335 R338 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 502 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQLITEEVRQELLAITPFTYVGYT 4mx2 E 1.9 BS02 AMP F 1 R40 Y41 N335 R17 Y18 N303 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQLITEEVRQELLAITPFTYVGYT 4mx2 F 1.9 BS01 AMP E 1 R40 Y41 I331 N335 R17 Y18 I299 N303 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 502 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPHVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 F 1.9 BS02 AMP F 1 N117 H118 S149 Q150 R361 L363 S366 T367 R370 N94 H95 S126 Q127 R329 L331 S334 T335 R338 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPHVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 G 1.9 BS01 AMP G 1 N117 H118 D119 S149 R361 L363 S366 T367 R370 N94 H95 D96 S126 R329 L331 S334 T335 R338 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGHVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTA 4mx2 G 1.9 BS02 AMP H 1 R40 Y41 I331 N335 R17 Y18 I299 N303 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGHVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTA 4mx2 H 1.9 BS01 AMP G 1 R40 Y41 I331 N335 R17 Y18 I299 N303 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKPYEALKDVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 H 1.9 BS02 AMP H 1 N117 H118 D119 S149 R361 L363 S366 T367 R370 N94 H95 D96 S126 R329 L331 S334 T335 R338 H118 T195 H196 E334 H95 T172 H173 E302 4.3.2.2 0000166,0003824,0004018,0006164,0006188,0006189,0009152,0016829,0044208,0070626 A7LBL3 501 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKPYEALKDVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4ndf A 1.944 BS03 AMP A 1 L171 S174 D193 K194 Y195 H251 P254 S255 M256 H260 H262 L11 S14 D33 K34 Y35 H91 P94 S95 M96 H100 H102 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 24362567 401 GSHMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 4ndf B 1.944 BS03 AMP B 1 L171 D193 K194 Y195 L203 H251 S255 M256 H260 H262 L11 D33 K34 Y35 L43 H91 S95 M96 H100 H102 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 24362567 401 GSHMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 4ndh A 1.848 BS03 AMP A 1 L171 S174 D193 K194 Y195 H251 S255 M256 H260 H262 L11 S14 D33 K34 Y35 H91 S95 M96 H100 H102 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 24362567 401 GSHMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 4ndh B 1.848 BS03 AMP B 1 L171 S174 D193 K194 L203 H251 S255 M256 H260 H262 L9 S12 D31 K32 L41 H89 S93 M94 H98 H100 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 24362567 401 HMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 4ndi A 1.9 BS03 AMP A 1 L171 S174 M180 D193 K194 Y195 H251 P254 S255 M256 H260 H262 L11 S14 M20 D33 K34 Y35 H91 P94 S95 M96 H100 H102 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 24362567 401 GSHMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPQARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 4ndi B 1.9 BS03 AMP B 1 L171 D193 K194 Y195 L203 H251 S255 M256 H260 H262 L11 D33 K34 Y35 L43 H91 S95 M96 H100 H102 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 24362567 401 GSHMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPQARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 4nnj A 2.4 BS01 AMP B 1 A444 D470 K494 K519 V520 A542 L543 D544 N545 A434 D460 K484 K509 V510 A532 L533 D534 N535 R21 R481 D544 C600 T601 R603 N781 D782 R11 R471 D534 C590 T591 R593 N771 D772 6.2.1.45 0004839,0005515,0005524,0005634,0005737,0006511,0006974,0008641,0016567,0016874,0036211,0043412 P22515 24816100 101 AGEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKQSGDVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPDEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL 4nnj C 2.4 BS01 AMP D 1 G443 A444 D470 K494 K519 V520 A542 L543 D544 N545 G433 A434 D460 K484 K509 V510 A532 L533 D534 N535 R21 R481 D544 C600 T601 R603 N781 D782 R11 R471 D534 C590 T591 R593 N771 D772 6.2.1.45 0004839,0005515,0005524,0005634,0005737,0006511,0006974,0008641,0016567,0016874,0036211,0043412 P22515 24816100 101 AGEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKQSGDVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPDEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL 4o6r A 1.9 BS01 AMP A 1 I145 V146 K172 G205 G209 Q210 F223 G225 S226 T229 R232 I146 V147 K173 G206 G210 Q211 F224 G226 S227 T230 R233 N149 K172 E247 C281 E382 E459 N150 K173 E248 C282 E383 E460 ? 0000166,0016491,0016620 B4EJX1 501 HMQTQLFIDGRFVDAVDRGTIDVLNPHDGSVITKIAAATAADVDLAVDAATRAFPAWSAMPAAERGRLLLRLADAIEANTEALAQLESLDTGHPIRDSRALDVPRTAACFRYFGGMADKLQGSVIPVDTGFLNYVQRAPIGVVGQIVPWNFPLMFTSWKMGPALAAGNTVVLKPSEITPLSTLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVGKIAFTGSTATGRRIVEASQGNLKRVQLELGGKGANIVFDDANLDAAINGAAWAIFHNQGQACIAGSRLVLHERIADAFLERFVALASSIRIGNPLDPNTEMGPLTSKQHLDRVLSYVDVAREQGGRVLTGGSAPQDPALANGYYVRPTIVEAKHATDRVAQEEVFGPFVTVLRFGSDDEALAIANATEYGLGSGLWTNDLSRAHRMAARIDAGMCWINCYKRVNPGSPFGGVGKSGYGREMGFEAMHDYTEARSVWVNVDGNVPPHFKR 4o6r B 1.9 BS01 AMP B 1 I145 V146 K172 G205 G209 Q210 F223 G225 S226 T229 I146 V147 K173 G206 G210 Q211 F224 G226 S227 T230 N149 K172 E247 C281 E382 E459 N150 K173 E248 C282 E383 E460 ? 0000166,0016491,0016620 B4EJX1 501 HMQTQLFIDGRFVDAVDRGTIDVLNPHDGSVITKIAAATAADVDLAVDAATRAFPAWSAMPAAERGRLLLRLADAIEANTEALAQLESLDTGHPIRDSRALDVPRTAACFRYFGGMADKLQGSVIPVDTGFLNYVQRAPIGVVGQIVPWNFPLMFTSWKMGPALAAGNTVVLKPSEITPLSTLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVGKIAFTGSTATGRRIVEASQGNLKRVQLELGGKGANIVFDDANLDAAINGAAWAIFHNQGQACIAGSRLVLHERIADAFLERFVALASSIRIGNPLDPNTEMGPLTSKQHLDRVLSYVDVAREQGGRVLTGGSAPQDPALANGYYVRPTIVEAKHATDRVAQEEVFGPFVTVLRFGSDDEALAIANATEYGLGSGLWTNDLSRAHRMAARIDAGMCWINCYKRVNPGSPFGGVGKSGYGREMGFEAMHDYTEARSVWVNVDGNVPPHFKR 4o6r C 1.9 BS01 AMP C 1 I145 V146 K172 G205 G209 Q210 F223 G225 S226 T229 I146 V147 K173 G206 G210 Q211 F224 G226 S227 T230 N149 K172 E247 C281 E382 E459 N150 K173 E248 C282 E383 E460 ? 0000166,0016491,0016620 B4EJX1 502 HMQTQLFIDGRFVDAVDRGTIDVLNPHDGSVITKIAAATAADVDLAVDAATRAFPAWSAMPAAERGRLLLRLADAIEANTEALAQLESLDTGHPIRDSRALDVPRTAACFRYFGGMADKLQGSVIPVDTGFLNYVQRAPIGVVGQIVPWNFPLMFTSWKMGPALAAGNTVVLKPSEITPLSTLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVGKIAFTGSTATGRRIVEASQGNLKRVQLELGGKGANIVFDDANLDAAINGAAWAIFHNQGQACIAGSRLVLHERIADAFLERFVALASSIRIGNPLDPNTEMGPLTSKQHLDRVLSYVDVAREQGGRVLTGGSAPQDPALANGYYVRPTIVEAKHATDRVAQEEVFGPFVTVLRFGSDDEALAIANATEYGLGSGLWTNDLSRAHRMAARIDAGMCWINCYKRVNPGSPFGGVGKSGYGREMGFEAMHDYTEARSVWVNVDGNVPPHFKR 4o6r D 1.9 BS01 AMP D 1 I145 V146 K172 G205 G209 F223 G225 S226 T229 I146 V147 K173 G206 G210 F224 G226 S227 T230 N149 K172 E247 C281 E382 E459 N150 K173 E248 C282 E383 E460 ? 0000166,0016491,0016620 B4EJX1 502 HMQTQLFIDGRFVDAVDRGTIDVLNPHDGSVITKIAAATAADVDLAVDAATRAFPAWSAMPAAERGRLLLRLADAIEANTEALAQLESLDTGHPIRDSRALDVPRTAACFRYFGGMADKLQGSVIPVDTGFLNYVQRAPIGVVGQIVPWNFPLMFTSWKMGPALAAGNTVVLKPSEITPLSTLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVGKIAFTGSTATGRRIVEASQGNLKRVQLELGGKGANIVFDDANLDAAINGAAWAIFHNQGQACIAGSRLVLHERIADAFLERFVALASSIRIGNPLDPNTEMGPLTSKQHLDRVLSYVDVAREQGGRVLTGGSAPQDPALANGYYVRPTIVEAKHATDRVAQEEVFGPFVTVLRFGSDDEALAIANATEYGLGSGLWTNDLSRAHRMAARIDAGMCWINCYKRVNPGSPFGGVGKSGYGREMGFEAMHDYTEARSVWVNVDGNVPPHFKR 4o81 A 2.1 BS01 AMP A 1 K13 M15 H68 L83 M85 E177 D190 K2 M4 H57 L72 M74 E166 D179 6.3.2.6 0004639,0005524,0006164,0006189,0009236,0016874 O57978 308 AKKMIPIDDDKLIMEFKDDATAFDGTKKARFKGKGWLNAQLSVIFFKLLEEHGIKTHFIGVAGGNRLIVEKLDMYPLEVVVRNVVAGSLKKRLPLPEGYELPEPIVELYYKNDELHDPMINYYHAKVLGISLDEIKKIEEIALKVNEILKDYLAKKGIILVDFKLEFGKDKNGDIVLADEISPDTCRFWDAKTKRSLDKDVFRFDKGDLIEAYKEIYERITGEKPEF 4o81 A 2.1 BS02 AMP A 2 E89 R93 G98 S99 D173 K175 T196 C197 R198 E78 R82 G87 S88 D162 K164 T185 C186 R187 6.3.2.6 0004639,0005524,0006164,0006189,0009236,0016874 O57978 309 AKKMIPIDDDKLIMEFKDDATAFDGTKKARFKGKGWLNAQLSVIFFKLLEEHGIKTHFIGVAGGNRLIVEKLDMYPLEVVVRNVVAGSLKKRLPLPEGYELPEPIVELYYKNDELHDPMINYYHAKVLGISLDEIKKIEEIALKVNEILKDYLAKKGIILVDFKLEFGKDKNGDIVLADEISPDTCRFWDAKTKRSLDKDVFRFDKGDLIEAYKEIYERITGEKPEF 4o81 B 2.1 BS02 AMP B 1 E89 R93 S99 D173 K175 T196 C197 R198 E78 R82 S88 D162 K164 T185 C186 R187 6.3.2.6 0004639,0005524,0006164,0006189,0009236,0016874 O57978 312 AKKMIPIDDDKLIMEFKDDATAFDGTKKARFKGKGWLNAQLSVIFFKLLEEHGIKTHFIGVAGGNRLIVEKLDMYPLEVVVRNVVAGSLKKRLPLPEGYELPEPIVELYYKNDELHDPMINYYHAKVLGISLDEIKKIEEIALKVNEILKDYLAKKGIILVDFKLEFGKDKNGDIVLADEISPDTCRFWDAKTKRSLDKDVFRFDKGDLIEAYKEIYERITGEKP 4o82 A 2.16 BS01 AMP A 1 E89 R93 G98 S99 D173 K175 T196 C197 R198 E78 R82 G87 S88 D162 K164 T185 C186 R187 6.3.2.6 0004639,0005524,0006164,0006189,0009236,0016874 O57978 307 AKKMIPIDDDKLIMEFKDDATAFDGTKKARFKGKGWLNAQLSVIFFKLLEEHGIKTHFIGVAGGNRLIVEKLDMYPLEVVVRNVVAGSLKKRLPLPEGYELPEPIVELYYKNDELHDPMINYYHAKVLGISLDEIKKIEEIALKVNEILKDYLAKKGIILVDFKLEFGKDKNGDIVLADEISPDTCRFWDAKTKRSLDKDVFRFDKGDLIEAYKEIYERITGEKPEF 4o82 B 2.16 BS01 AMP B 1 E89 R93 S99 D173 K175 T196 C197 R198 E78 R82 S88 D162 K164 T185 C186 R187 6.3.2.6 0004639,0005524,0006164,0006189,0009236,0016874 O57978 411 AKKMIPIDDDKLIMEFKDDATAFDGTKKARFKGKGWLNAQLSVIFFKLLEEHGIKTHFIGVAGGNRLIVEKLDMYPLEVVVRNVVAGSLKKRLPLPEGYELPEPIVELYYKNDELHDPMINYYHAKVLGISLDEIKKIEEIALKVNEILKDYLAKKGIILVDFKLEFGKDKNGDIVLADEISPDTCRFWDAKTKRSLDKDVFRFDKGDLIEAYKEIYERITGEKPE 4o83 A 2.05 BS01 AMP A 1 K13 M15 H68 L83 M85 E177 D190 K2 M4 H57 L72 M74 E166 D179 6.3.2.6 0004639,0005524,0006164,0006189,0009236,0016874 O57978 310 AKKMIPIDDDKLIMEFKDDATAFDGTKKARFKGKGWLNAQLSVIFFKLLEEHGIKTHFIGVAGGNRLIVEKLDMYPLEVVVRNVVAGSLKKRLPLPEGYELPEPIVELYYKNDELHDPMINYYHAKVLGISLDEIKKIEEIALKVNEILKDYLAKKGIILVDFKLEFGKDKNGDIVLADEISPDTCRFWDAKTKRSLDKDVFRFDKGDLIEAYKEIYERITGEKPEF 4oke A 1.7 BS01 AMP A 1 D6 E8 F9 W46 V47 H140 D6 E8 F9 W46 V47 H140 3.1.13.- 0000287,0003676,0004527,0004532,0008408,0042802,0046872 P9WJ73 24704253 201 VRYFYDTEFIEDGHTIELISIGVVAEDGREYYAVSTEFDPERAGSWVRTHVLPKLPPPASQLWRSRQQIRLDLEEFLRIDGTDSIELWAWVGAYDHVALCQLWGPMTALPPTVPRFTRELRQLWEDRGCPRMPPRPRDVHDALVDARDQLRRFRLITSTD 4oke A 1.7 BS02 AMP A 2 M106 R115 M106 R115 3.1.13.- 0000287,0003676,0004527,0004532,0008408,0042802,0046872 P9WJ73 24704253 203 VRYFYDTEFIEDGHTIELISIGVVAEDGREYYAVSTEFDPERAGSWVRTHVLPKLPPPASQLWRSRQQIRLDLEEFLRIDGTDSIELWAWVGAYDHVALCQLWGPMTALPPTVPRFTRELRQLWEDRGCPRMPPRPRDVHDALVDARDQLRRFRLITSTD 4oke B 1.7 BS01 AMP A 2 W90 V91 Y94 R121 W90 V91 Y94 R121 3.1.13.- 0000287,0003676,0004527,0004532,0008408,0042802,0046872 P9WJ73 24704253 203 VRYFYDTEFIEDGHTIELISIGVVAEDGREYYAVSTEFDPERAGSWVRTHVLPKLPPPASQLWRSRQQIRLDLEEFLRIDGTDSIELWAWVGAYDHVALCQLWGPMTALPPTVPRFTRELRQLWEDRGCPRMPPRPRDVHDALVDARDQLRRFRLITS 4oke B 1.7 BS02 AMP B 1 D6 E8 F9 W46 V47 H140 D6 E8 F9 W46 V47 H140 3.1.13.- 0000287,0003676,0004527,0004532,0008408,0042802,0046872 P9WJ73 24704253 201 VRYFYDTEFIEDGHTIELISIGVVAEDGREYYAVSTEFDPERAGSWVRTHVLPKLPPPASQLWRSRQQIRLDLEEFLRIDGTDSIELWAWVGAYDHVALCQLWGPMTALPPTVPRFTRELRQLWEDRGCPRMPPRPRDVHDALVDARDQLRRFRLITS 4ozl A 1.4942 BS01 AMP A 1 I18 G46 R47 G98 G100 K101 I14 G42 R43 G79 G81 K82 ? 0005524,0005737,0005829,0006808,0030234 -logKd/Ki=4.97, Kd=10.6uM B8ZYW1 24946894 201 DLPNDGGIKLVMAIIRPDKLADVKTALAEVGAPSLTVTNVSGRGSDLHQKVKVECVVADTPAEDVADAIADAAHTGEKGDGKIFILPVENAIQVRTGKTGRDAV 4p1g A 2.603 BS01 AMP A 1 C456 F457 Y478 R480 T568 D571 C28 F29 Y50 R52 T140 D143 ? 0010960 Q3TWN3 1000 MEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSE 4p69 A 3.3 BS01 AMP A 1 N104 H113 L116 K291 K294 T295 Y298 E376 N95 H104 L107 K274 K277 T278 Y281 E359 2.7.11.5,3.1.3.- 0004674,0004721,0005524,0005737,0006006,0006097,0006099,0006470,0008772,0016208,0016310,0016788,0016791,0018105,0050790 Q8X607 25272278 601 GLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYAEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSV 4p69 B 3.3 BS02 AMP B 1 N104 S105 H113 K291 K294 T295 Y298 N94 S95 H103 K281 K284 T285 Y288 2.7.11.5,3.1.3.- 0004674,0004721,0005524,0005737,0006006,0006097,0006099,0006470,0008772,0016208,0016310,0016788,0016791,0018105,0050790 Q8X607 25272278 602 LELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYAEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSV 4q86 A 2.25 BS01 AMP A 1 K9 K61 A70 S71 G74 E75 E78 S184 A185 Q195 R286 K8 K60 A69 S70 G73 E74 E77 S183 A184 Q194 R285 ? 0000287,0005829,0047693 P75838 25129028 601 TQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAF 4q86 B 2.25 BS01 AMP B 1 K9 F20 K61 S71 G74 E75 E78 S184 A185 N187 Q195 R286 K8 F19 K60 S70 G73 E74 E77 S183 A184 N186 Q194 R285 ? 0000287,0005829,0047693 P75838 25129028 601 TQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAFW 4q86 C 2.25 BS01 AMP C 1 F20 K61 A70 S71 G74 E75 E78 S184 A185 N187 Q195 R286 F9 K50 A59 S60 G63 E64 E67 S173 A174 N176 Q184 R275 ? 0000287,0005829,0047693 P75838 25129028 601 ALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKA 4q86 D 2.25 BS01 AMP D 1 K9 K61 A70 S71 G74 E75 E78 S184 A185 Q195 R286 K8 K60 A69 S70 G73 E74 E77 S183 A184 Q194 R285 ? 0000287,0005829,0047693 P75838 25129028 601 TQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAF 4q86 E 2.25 BS01 AMP E 1 K9 K61 S71 G74 E75 E78 S184 A185 E191 Q195 R286 K6 K58 S68 G71 E72 E75 S181 A182 E188 Q192 R283 ? 0000287,0005829,0047693 P75838 25129028 601 TFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKA 4q86 G 2.25 BS01 AMP G 1 K9 F20 K61 S71 G74 E75 E78 S184 A185 N187 Q195 R286 K3 F14 K55 S65 G68 E69 E72 S178 A179 N181 Q189 R280 ? 0000287,0005829,0047693 P75838 25129028 601 PGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKA 4q86 H 2.25 BS01 AMP H 1 K9 F20 K61 A70 S71 G74 E75 E78 S184 A185 N187 Q195 R286 K8 F19 K60 A69 S70 G73 E74 E77 S183 A184 N186 Q194 R285 ? 0000287,0005829,0047693 P75838 25129028 601 TQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAFW 4qei A 2.875 BS02 AMP A 1 R277 I287 V289 F292 M294 E403 I404 G526 R529 R172 I182 V184 F187 M189 E290 I291 G408 R411 2.7.7.-,6.1.1.14 0000166,0004812,0004820,0005524,0005737,0006418,0006426 P41250 26797133 701 IVDRAKMGDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGERFRADHLLKAHLQKLQQELADLFVNFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMEDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTIETQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETGKK 4qfg C 3.46 BS01 AMP C 1 H150 T199 I203 A204 V224 S225 I311 S313 S315 D316 H122 T171 I175 A176 V196 S197 I276 S278 S280 D281 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 -logKd/Ki=5.48, Kd=3.3uM P80385 25066137 401 SSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 4qfr C 3.34 BS01 AMP C 1 H150 T199 I203 A204 V224 S225 H297 I311 S313 D316 H123 T162 I166 A167 V187 S188 H254 I268 S270 D273 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 25066137 401 YTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 4qfr C 3.34 BS02 AMP C 2 R69 K169 I239 S241 F243 D244 R268 V275 L276 V296 H297 R298 R42 K142 I202 S204 F206 D207 R231 V232 L233 V253 H254 R255 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 25066137 402 YTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 4qfs C 3.55 BS01 AMP C 1 H150 I203 A204 V224 S225 H297 S313 S315 D316 H123 I160 A161 V181 S182 H247 S258 S260 D261 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 25066137 401 YTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITSLEELQIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRLKCYLHETLEAIINRLVEAEVHRLVDVVKGIVSLSDILQALV 4r1l A 2.42 BS03 AMP A 1 A214 E215 P216 S236 F237 G238 M239 T240 D304 R328 N339 A215 E216 P217 S237 F238 G239 M240 T241 D305 R329 N340 6.2.1.30 0000166,0010124,0016874,0046872,0047475 Q8AAN6 503 GMSTQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSGTTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEAVRVKDLRDN 4r1l C 2.42 BS02 AMP C 1 A214 E215 P216 S236 G238 M239 T240 D304 R328 I334 N339 A215 E216 P217 S237 G239 M240 T241 D305 R329 I335 N340 6.2.1.30 0000166,0010124,0016874,0046872,0047475 Q8AAN6 502 GMSTQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSGTTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLRD 4r1m A 2.48 BS02 AMP A 1 A214 E215 P216 N235 S236 F237 G238 M239 T240 D304 R328 I334 N339 A215 E216 P217 N236 S237 F238 G239 M240 T241 D305 R329 I335 N340 6.2.1.30 0000166,0010124,0016874,0046872,0047475 Q8AAN6 502 GMSTQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSGTTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLRDN 4r1m B 2.48 BS02 AMP B 1 A214 E215 P216 S236 F237 G238 M239 T240 D304 I325 R328 K424 A208 E209 P210 S230 F231 G232 M233 T234 D298 I319 R322 K418 6.2.1.30 0000166,0010124,0016874,0046872,0047475 Q8AAN6 502 TQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLR 4r1m D 2.48 BS02 AMP D 1 A214 E215 P216 N235 S236 F237 G238 M239 T240 D304 R328 K424 A208 E209 P210 N229 S230 F231 G232 M233 T234 D298 R322 K418 6.2.1.30 0000166,0010124,0016874,0046872,0047475 Q8AAN6 502 STQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLRDN 4r78 A 1.45 BS01 AMP A 1 N32 I43 E89 Y90 I91 T96 E180 N181 I183 I193 D194 N35 I46 E92 Y93 I94 T99 E183 N184 I186 I196 D197 2.7.1.32 0000166,0016301,0016310 Q8DPI4 25781969 302 GSHMEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIVKFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSIKTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLEKRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTSQEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRAVKGLASYG 4rdh A 2.1 BS01 AMP A 1 G37 G39 G40 D61 R72 K85 F108 V109 I129 S131 P134 G36 G38 G39 D60 R71 K84 F107 V108 I128 S130 P133 6.1.-.- 0005515,0005524,0008641,0016020,0016874,0030955,0031402,0042803,0061503,0061504 Q46927 26101842 301 SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSGFGAATMVTATFGFVAVSHALKKMMAKAARQ 4rdh B 2.1 BS01 AMP B 1 G37 G40 D61 R72 K85 F108 V109 I129 D130 G36 G39 D60 R71 K84 F107 V108 I128 D129 6.1.-.- 0005515,0005524,0008641,0016020,0016874,0030955,0031402,0042803,0061503,0061504 Q46927 26101842 301 SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPGFGAATMVTATFGFVAVSHALKKMMAKAARQ 4rdh C 2.1 BS01 AMP C 1 G37 G40 D61 R72 K85 F108 V109 I129 D130 P134 G36 G39 D60 R71 K84 F107 V108 I128 D129 P133 6.1.-.- 0005515,0005524,0008641,0016020,0016874,0030955,0031402,0042803,0061503,0061504 Q46927 26101842 301 SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPGFGAATMVTATFGFVAVSHALKKMMAKAARQ 4rdh D 2.1 BS01 AMP D 1 G37 G40 D61 D63 R72 K85 F108 V109 I129 D130 P134 G35 G38 D59 D61 R70 K83 F106 V107 I127 D128 P132 6.1.-.- 0005515,0005524,0008641,0016020,0016874,0030955,0031402,0042803,0061503,0061504 Q46927 26101842 301 VVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVGFGAATMVTATFGFVAVSHALKKMMAKAARQ 4rdx A 2.55 BS02 AMP A 1 R112 R120 Y121 F124 Q126 A281 L282 G283 G308 R311 R100 R108 Y109 F112 Q114 A269 L270 G271 G296 R299 6.1.1.21 0004812,0004821,0005524,0005737,0006412,0006427 P62374 25722375 501 TARAVRGTKDLFGKELRMHQRIVATARKVLEAAGALELVTPIFEETQVFEKEMFTFQDRGGRSLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQKGRYRQFHQVNYEALGSENPILDAEAVVLLYECLKELGLRRLKVKLSSVGDPEDRARYNAYLREVLSPHREALSEDSKERLELNPMRILDSKSERDQALLKELGVRPMLDFLGEEARAHLKEVERHLERLSVPYELEPALVRGLDYYVRTAFEVHHEEIGAQSALGGGGRYDGLSELLGGPRVPGVGFAFGVERVALALEAEGFGLPEEKGPDLYLIPLTEEAVAEAFYLAEALRPRLRAEYALAPRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLATGEQVRLSREEVPGYLLQALG 4rer G 4.047 BS01 AMP G 1 T87 T89 D90 Y121 L129 V130 I150 H151 R152 T63 T65 D66 Y97 L105 V106 I126 H127 R128 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 25412657 401 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 4rer G 4.047 BS02 AMP G 2 R70 I240 S242 F244 D245 R269 V276 L277 V297 H298 R299 R46 I216 S218 F220 D221 R245 V252 L253 V273 H274 R275 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 25412657 402 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 4rer G 4.047 BS03 AMP G 3 H151 T200 A205 V225 S226 H298 I312 S314 S316 D317 H127 T176 A181 V201 S202 H274 I288 S290 S292 D293 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 25412657 403 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 4rew G 4.58 BS01 AMP G 1 M84 T86 T88 D89 Y120 L128 I149 H150 R151 M61 T63 T65 D66 Y97 L105 I126 H127 R128 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 25412657 401 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4rew G 4.58 BS02 AMP G 2 R69 I239 S241 F243 D244 R268 L276 V296 H297 R298 R46 I216 S218 F220 D221 R245 L253 V273 H274 R275 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 25412657 402 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4rew G 4.58 BS03 AMP G 3 H150 T199 A204 V224 S225 H297 I311 S313 S315 D316 H127 T176 A181 V201 S202 H274 I288 S290 S292 D293 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 25412657 403 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4rvn A 2.2 BS02 AMP A 1 A214 E215 P216 S236 F237 G238 M239 T240 D304 I325 R328 I334 N339 A215 E216 P217 S237 F238 G239 M240 T241 D305 I326 R329 I335 N340 6.2.1.30 0000166,0010124,0016874,0046872,0047475 Q8AAN6 502 GMSTQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSGTTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEAVRVKDLRDN 4rvn B 2.2 BS02 AMP B 1 S94 A214 E215 P216 S236 F237 G238 M239 T240 D304 I325 R328 K424 S92 A210 E211 P212 S232 F233 G234 M235 T236 D300 I321 R324 K416 6.2.1.30 0000166,0010124,0016874,0046872,0047475 Q8AAN6 502 TQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLR 4rvn C 2.2 BS02 AMP C 1 A214 E215 P216 S236 G238 M239 T240 D304 I325 R328 I334 N339 A215 E216 P217 S237 G239 M240 T241 D305 I326 R329 I335 N340 6.2.1.30 0000166,0010124,0016874,0046872,0047475 Q8AAN6 502 GMSTQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSGTTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLRD 4rvn D 2.2 BS02 AMP D 1 A214 P216 S236 F237 G238 M239 T240 D304 I325 R328 K424 A208 P210 S230 F231 G232 M233 T234 D298 I319 R322 K416 6.2.1.30 0000166,0010124,0016874,0046872,0047475 Q8AAN6 502 STQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLRDN 4ts5 A 2.4 BS01 AMP A 1 D95 D96 I97 D99 T100 G101 S103 W148 F149 D94 D95 I96 D98 T99 G100 S102 W147 F148 D95 D96 D99 D94 D95 D98 2.4.2.- 0000166,0016757 Q97W95 25790177 301 QKIPVKVVTWDEIVSLSTKLAEKIKADEYNVNVIVAIARGGLVPARLVADVLGVFDILSIKIEHWIETASHTPEAKVKYPFKVDLSDKNVLIIDDITDTGDSIELARKYVMENFRPTEVKTATLQYIKPAAKIIPDYYAEEIVSWAWFMYPWNYWEDEINLVNKILIERKTKDIDINELKRNFVESYGIENPPISLDKILTEMKRRKIV 4ts5 B 2.4 BS01 AMP B 1 D95 D96 I97 D99 T100 G101 S103 W148 F149 D94 D95 I96 D98 T99 G100 S102 W147 F148 D95 D96 D99 D94 D95 D98 2.4.2.- 0000166,0016757 Q97W95 25790177 301 QKIPVKVVTWDEIVSLSTKLAEKIKADEYNVNVIVAIARGGLVPARLVADVLGVFDILSIKIEHWIETASHTPEAKVKYPFKVDLSDKNVLIIDDITDTGDSIELARKYVMENFRPTEVKTATLQYIKPAAKIIPDYYAEEIVSWAWFMYPWNYWEDEINLVNKILIERKTKDIDINELKRNFVESYGIENPPISLDKILTEMKRRKIV 4twb A 2.802 BS01 AMP A 1 R93 F98 H127 R93 F98 H127 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q97Z86 25605536 301 MIIIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIEDPFILAPDRGALDRARKIAEEINAPYSYIEKERNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 4twb A 2.802 BS02 AMP A 2 F32 D34 E36 F32 D34 E36 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q97Z86 25605536 303 MIIIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIEDPFILAPDRGALDRARKIAEEINAPYSYIEKERNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 4twb B 2.802 BS01 AMP A 1 F32 D34 E36 F32 D34 E36 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q97Z86 25605536 301 MIIIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIEDPFILAPDRGALDRARKIAEEINAPYSYIEKERNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 4twb B 2.802 BS02 AMP A 2 R93 F98 H127 R93 F98 H127 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q97Z86 25605536 303 MIIIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIEDPFILAPDRGALDRARKIAEEINAPYSYIEKERNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 4twb C 2.802 BS01 AMP C 1 R93 F98 H127 R93 F98 H127 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q97Z86 25605536 301 MIIIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIEDPFILAPDRGALDRARKIAEEINAPYSYIEKERNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 4twb C 2.802 BS02 AMP C 2 F32 E36 F32 E36 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q97Z86 25605536 303 MIIIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIEDPFILAPDRGALDRARKIAEEINAPYSYIEKERNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 4twb D 2.802 BS01 AMP C 1 F32 D34 E36 F32 D34 E36 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q97Z86 25605536 301 MIIIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIEDPFILAPDRGALDRARKIAEEINAPYSYIEKERNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 4twb D 2.802 BS02 AMP C 2 R93 F98 H127 R93 F98 H127 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q97Z86 25605536 303 MIIIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIEDPFILAPDRGALDRARKIAEEINAPYSYIEKERNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 4twb E 2.802 BS01 AMP E 1 F32 D34 E36 F32 D34 E36 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q97Z86 25605536 302 MIIIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIEDPFILAPDRGALDRARKIAEEINAPYSYIEKERNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 4twb E 2.802 BS02 AMP F 1 R93 F98 H127 R93 F98 H127 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q97Z86 25605536 301 MIIIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIEDPFILAPDRGALDRARKIAEEINAPYSYIEKERNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 4twb F 2.802 BS01 AMP E 1 R93 F98 H127 R93 F98 H127 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q97Z86 25605536 302 MIIIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIEDPFILAPDRGALDRARKIAEEINAPYSYIEKERNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 4twb F 2.802 BS02 AMP F 1 F32 D34 E36 F32 D34 E36 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009165,0016301,0016310,0046872 Q97Z86 25605536 301 MIIIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIEDPFILAPDRGALDRARKIAEEINAPYSYIEKERNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKSVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 4uuw A 1.98 BS01 AMP A 1 L13 T18 L19 D20 T21 N22 L13 T18 L19 D20 T21 N22 ? 0005524,0046872 Q5SHB0 25313401 400 MERAEILGVGTELLYGETLDTNTAEIARSLKPYALKVERTLRVADEVAPLAREVEEAFARARLVVLSGGLGPTPDDVTREAVALALGEPLELDEAVLGEIEAFFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVLLPGPPPEWRPMWQEVLPRLGLPRRPYAERVLKTWGIGESEIVERLGPLFVREEEVEVGTYPKVHGVEVVVRGREDRVAELAERIKKKLLKEVWGEGEMTLAEAVKRRMEREGATLSTMESLTGGLLGAEITRVPGASRFYLGGVVSYSVGAKARFGVPQDLLSRTVSAETARAMAEAARSLFGSTYALATTGVAGPDPLEGEPPGTVYVALAGPTGAEVRRYRFPGDRETVRLRSVYAALALLVT 4v1u A 2.86 BS03 AMP A 1 R344 K409 Q415 S419 C422 E423 E426 A533 A534 N536 R636 R315 K380 Q386 S390 C393 E394 E397 A504 A505 N507 R607 ? 0000166,0046872 A0YXD2 26098679 777 LLQIQPHFHVEVIEPKQVYLLGEQANHALTGQLYCQILPLLNGQYTLEQIVEKLDGEVPPEYIDYVLERLAEKGYLTEAAPELSSEVAAFWSELGIAPPVAAEALRQPVTLTPVGNISEVTVAALTTALRDIGISVQTALNVVLTDDYLQPELAKINKQALESQQTWLLVKPVGSVLWLGPVFVPGKTGCWDCLAHRLRGNREVEASVLRQKQAQGCLPTARATLPSTLQTGLQFAATEIAKWIVKYHVNATAPGTVFFPTLDGKIITLNHSILDLKSHILIKRSQCPTCGDPKILQHRGFEPLKLESRPKQGHRGTTPEQTVQKYQHLISPVTGVVTELVRITDPANPLVHTYRAGHSFGSATSLRGLRNTLKHKSSGKGKTDSQSKASGLCEAVERYSGIFQGDEPRKRATLAELGDLAIHPEQCLCFSDGQYANRETLNEQATVAHDWIPQRFDASQAIEWTPVWSLTEQTHKYLPTALCYYHYPLPPEHRFARGDSNGNAAGNTLEEAILQGFMELVERDGVALWWYNRLRRPAVDLGSFNEPYFVQLQQFYRENDRDLWVLDLTADLGIPAFAGVSNRKTGSSERLILGFGAHLDPTIAILRAVTEVNQIGLELDKVPDENLKSDATDWLITEKLADHPYLLPDTTQPLKTAQDYPKRWSDDIYTDVMTCVNIAQQAGLETLVIDQTRPDIGLNVVKVTVPGMRHFWSRFGEGRLYDVPVKLGWLDEPLTEAQMNPTPMPF 4v1u B 2.86 BS03 AMP B 1 R344 K409 S419 C422 E423 E426 A533 A534 N536 R636 R316 K379 S389 C392 E393 E396 A503 A504 N506 R604 ? 0000166,0046872 A0YXD2 26098679 777 LLQIQPHFHVEVIEPKQVYLLGEQANHALTGQLYCQILPLLNGQYTLEQIVEKLDGEVPPEYIDYVLERLAEKGYLTEAAPELSSEVAAFWSELGIAPPVAAEALRQPVTLTPVGNISEVTVAALTTALRDIGISVQTTALNVVLTDDYLQPELAKINKQALESQQTWLLVKPVGSVLWLGPVFVPGKTGCWDCLAHRLRGNREVEASVLRQKQAQGCLPTARATLPSTLQTGLQFAATEIAKWIVKYHVNATAPGTVFFPTLDGKIITLNHSILDLKSHILIKRSQCPTCGDPKILQHRGFEPLKLESRPKQGHRGTTPEQTVQKYQHLISPVTGVVTELVRITDPANPLVHTYRAGHGSATSLRGLRNTLKHKSSGKGKTDSQSKASGLCEAVERYSGIFQGDEPRKRATLAELGDLAIHPEQCLCFSDGQYANRETLNEQATVAHDWIPQRFDASQAIEWTPVWSLTEQTHKYLPTALCYYHYPLPPEHRFARGDSNGNAAGNTLEEAILQGFMELVERDGVALWWYNRLRRPAVDLGSFNEPYFVQLQQFYRENDRDLWVLDLTADLGIPAFAGVSNRKTSERLILGFGAHLDPTIAILRAVTEVNQIGLELDKVPDENLKSDATDWLITEKLADHPYLLPDTTQPLKTAQDYPKRWSDDIYTDVMTCVNIAQQAGLETLVIDQTRPDIGLNVVKVTVPGMRHFWSRFGEGRLYDVPVKLGWLDEPLTEAQMNPTPMPF 4wer A 2.05 BS01 AMP A 1 N9 S11 S12 T40 E41 G43 G66 G68 T69 N10 S12 S13 T41 E42 G44 G67 G69 T70 ? 0004143,0005524,0005886,0008654,0016301,0016310 Q830X4 401 AMKKAVLIVNPSSGGEKAKEFETLAEEKLKQLFDEVVVKQTEKGGDAEQFAREAAESHFDSVFVMGGDGTVNEGISGLAEQAYRPKFGFFPLGTVNDLARALNLPMDPEEAIQQLDLEKTSALDVGKINDDYFMNVVAIGTIKLGKLAYFISGAKHLANAQTYPFHLSLDQKEQTIESSTVLVGLTNSIGGFETLLPEAQVDDGKLHLVYLKDQSLWDAVKAVPDLLKGVDQSTDNLVYLTFKEGTISLENQEELTTNVDGDEGAALPITLKILPKHLTVYCGEE 4ww7 A 1.669 BS01 AMP A 1 S23 V30 I50 K52 E107 F108 L109 D182 S20 V26 I46 K48 E87 F88 L89 D162 2.7.11.1,3.6.-.- 0000282,0000408,0000722,0000723,0000781,0002949,0004672,0004674,0005515,0005524,0005634,0005654,0005694,0005737,0005829,0006338,0006468,0008033,0016310,0016787,0016887,0044024,0045944,0070525,0106310,1990145 P53323 25735745 301 EFIDKVSSYLTPDVDIAPISQGAAIVFTTTTHPYLPRAKDSHQKYIIKYRPRTLNESRLLAKLYLIPGLCVPQLIACDPYNGFIWLEFLGEDLPGGHGFSNLKNFLWMHDQDPYSDLVATTLRKVGRQIGLLHWNDYCHGDLTSSNIVLVRDGARWTPHLIDFGLGSVSNLVEDKGVDLYVLERAILSTHSKHAEKYNAWIMEGFEEVYREQGAKGAKKLKEVTKRFEEVRLRGRKR 4wyp A 1.502 BS01 AMP A 1 K41 P42 H119 F120 K41 P42 H119 F120 H12 K41 H119 F120 D121 H12 K41 H119 F120 D121 4.6.1.18 0003676,0004519,0004522,0004540,0005515,0005576,0016829,0050830 Kd=440uM -logKd/Ki=3.36, Kd=440uM P61823 26655472 401 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVGCEGNPYVPVHFDASV 4wyp B 1.502 BS01 AMP B 1 N67 H119 N68 H120 H12 K41 H119 F120 D121 H13 K42 H120 F121 D122 4.6.1.18 0003676,0004519,0004522,0004540,0005515,0005576,0016829,0050830 Kd=440uM P61823 26655472 401 MKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVGCEGNPYVPVHFDASV 4x44 A 2.0535 BS01 AMP A 1 F26 R27 R67 D128 L129 A131 T132 G133 G134 T135 F23 R24 R64 D125 L126 A128 T129 G130 G131 T132 R67 E104 R64 E101 2.4.2.7 0002055,0003999,0005515,0005576,0005654,0005737,0005829,0006166,0006168,0007625,0016208,0016757,0032263,0032264,0034774,0044209,0046083,0070062 P07741 1001 SELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKQGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 4x45 B 1.75 BS01 AMP B 1 F26 R27 R67 D128 L129 A131 T132 G133 T135 F25 R26 R66 D123 L124 A126 T127 G128 T130 R67 R66 2.4.2.7 0002055,0003999,0005515,0005576,0005654,0005737,0005829,0006166,0006168,0007625,0016208,0016757,0032263,0032264,0034774,0044209,0046083,0070062 P07741 201 ADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPGFSLLQYE 4xje A 1.88 BS01 AMP A 1 G28 D44 D46 D131 Y132 Y135 E138 H148 G27 D43 D45 D130 Y131 Y134 E137 H147 ? Q6X3H6 32100995 201 DTTQVTLIHKILAAADERNLPLWIGGGWAIDARLGRVTRKHDDIDLTFPGERRGELEAIVEMLGGRVMEELDYGFLAEIGDELLDCEPAWWADEAYEIAEAPQGSCPEAAEGVIAGRPVRCNSWEAIIWDYFYYADEVPPVDWPTKHIESYRLACTSLGAEKVEVLRAAFRSRYA 4y5q A 2.0 BS05 AMP A 1 G83 G85 V90 A103 K105 Y155 L205 D219 G18 G20 V25 A38 K40 Y90 L140 D154 D198 K200 E202 N203 D219 T238 D133 K135 E137 N138 D154 T170 ? 0004672,0005509,0005524,0006468 A3FQ16 605 LYFQGTFAERYNIVCMLGKGSFGEVLKCKDRITQQEYAVKVINKASAKNKDTSTILREVELLKKLDHPNIMKLFEILEDSSSFYIVGELYTGGELFDEIIKRKRFSEHDAARIIKQVFSGITYMHKHNIVHRDLKPENILLESKEKDCDIKIIDFGLSTCFQQNTDRIGTAYYIAPEVLRGTYDEKCDVWSAGVILYILLSGTPPFYGKNEYDILKRVETGKYAFDLPQWRTISDDAKDLIRKMLTFHPSLRITATQCLEHPWIQKYSSETPTISDLPSLESAMTNIRQFQAEKKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSGSTIEDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKDGSGKISTKELFKLFSEQVDNNKDGEVDFNEFVEMLQNFVRN 4yb6 A 1.98 BS01 AMP A 1 L170 S172 S173 G174 T176 L167 S169 S170 G171 T173 2.4.2.17 0000105,0000287,0003879,0005524,0005737,0016757,0046872 -logKd/Ki=5.32, Kd=4.8uM Q5HSJ4 27191057 301 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 B 1.98 BS01 AMP B 1 L170 S172 S173 G174 T176 L161 S163 S164 G165 T167 2.4.2.17 0000105,0000287,0003879,0005524,0005737,0016757,0046872 Q5HSJ4 27191057 301 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 C 1.98 BS02 AMP C 1 C104 L170 S172 S173 G174 T176 C100 L166 S168 S169 G170 T172 2.4.2.17 0000105,0000287,0003879,0005524,0005737,0016757,0046872 Q5HSJ4 27191057 301 TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 D 1.98 BS01 AMP D 1 C104 L170 S172 S173 G174 T176 C100 L166 S168 S169 G170 T172 2.4.2.17 0000105,0000287,0003879,0005524,0005737,0016757,0046872 -logKd/Ki=5.32, Kd=4.8uM Q5HSJ4 27191057 301 TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 E 1.98 BS02 AMP E 1 L170 S172 S173 G174 T176 L164 S166 S167 G168 T170 2.4.2.17 0000105,0000287,0003879,0005524,0005737,0016757,0046872 Q5HSJ4 27191057 301 NTRLRIAIQKSGRLSKESIELLSECGVKMHISLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 F 1.98 BS02 AMP F 1 L170 V171 S172 S173 G174 T176 L160 V161 S162 S163 G164 T166 2.4.2.17 0000105,0000287,0003879,0005524,0005737,0016757,0046872 Q5HSJ4 27191057 301 TRLRIAIQKSGRLSKESIELLSECGVKMHSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQEFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yed A 1.9 BS01 AMP A 1 G37 G39 G40 I60 D61 D63 R72 K85 F108 V109 I129 D130 P134 G36 G38 G39 I59 D60 D62 R71 K84 F107 V108 I128 D129 P133 6.1.-.- 0005515,0005524,0008641,0016020,0016874,0030955,0031402,0042803,0061503,0061504 Q46927 26101842 301 SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSGFGAATMVTATFGFVAVSHALKKMMAKAARQ 4yed B 1.9 BS01 AMP B 1 G37 G39 G40 D61 D63 R72 K85 F108 V109 I129 D130 S131 P134 G36 G38 G39 D60 D62 R71 K84 F107 V108 I128 D129 S130 P133 6.1.-.- 0005515,0005524,0008641,0016020,0016874,0030955,0031402,0042803,0061503,0061504 Q46927 26101842 301 SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKSGFGAATMVTATFGFVAVSHALKKMMAKAARQ 4yed C 1.9 BS01 AMP C 1 G37 G39 G40 D61 K85 F108 V109 D130 P134 G36 G38 G39 D60 K84 F107 V108 D129 P133 6.1.-.- 0005515,0005524,0008641,0016020,0016874,0030955,0031402,0042803,0061503,0061504 Q46927 26101842 301 SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMGFGAATMVTATFGFVAVSHALKKMMAKAARQ 4yed D 1.9 BS01 AMP D 1 G37 G40 I60 D61 D63 K85 F108 V109 D130 P134 G36 G39 I59 D60 D62 K84 F107 V108 D129 P133 6.1.-.- 0005515,0005524,0008641,0016020,0016874,0030955,0031402,0042803,0061503,0061504 Q46927 26101842 301 SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATGFGAATMVTATFGFVAVSHALKKMMAKAARQ 4zcf C 2.6 BS03 AMP C 1 T91 I119 G122 F126 D226 R537 T86 I114 G117 F121 D211 R465 3.1.21.5 0003677,0004386,0004519,0005524,0009307,0015668,0016787 Q5ZND2 26067164 1001 TLEKNLPHQKAGVDAVMNVFVSATPHLTDNVAVRLLANPELKLSEQQYYNNIKNVQAFNGIAHSKDNHNAKSNIIDVSMETGTGKTYTYIKTIFDLNKSFGINKFIIIVPTLSIKAGTVNFLKSDALKEHFRDDYKRELRTYVVESQKMPQAIHDFVEASNFKKYIHVLVINSGMINSKSLTDTYDTGLLDNQFNTPVDALRAVKPFIIIDEPHRFPTGKKTWENIEKFNAQYIIRYGATFSEGYKNLVYRLTAVDAFNDDLVKGIDAYIEDNANLKFVKDGKEATFFKLAKSLSKTHSAIHDLTLDALNTAVLSNGIELKIGSSINPYSYDQTLADNMMRKAVKEHFKLEKELLTQPRIKPLTLFFIDDLKTKFEEYVLAEANELLYKNYLEKTVTNISSVHGGYIEQEINEILHDKELLLSLDNPRRFIFSKWTLREGWDNPNVFQICKLRSSKLQEVGRGLRLPVNEYMCRVKNFTLKYYVDFTEKDFVDSLVKEVNESSPSKFTQELKEQIDNFKDSDAYSRLKSELKELWDLINQKAVIEYKINSESEFLSIFKSFMLEETERSYREFLDNLSQTIFVKHGTLHKVFCDIKDTILNIQTIRKIKSGFSKYLLNNSFSLGYNL 4zgl B 2.95 BS01 AMP B 1 D28 I29 G88 Q89 E90 H95 H97 D28 I29 G88 Q89 E90 H95 H97 ? 0003824,0005737,0005829,0043530,0055130 P64382 26750483 201 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSG 4zgl C 2.95 BS01 AMP C 1 V3 F26 D28 I29 Q89 E90 V91 H95 H97 V3 F26 D28 I29 Q89 E90 V91 H95 H97 ? 0003824,0005737,0005829,0043530,0055130 P64382 26750483 201 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSG 4zgl F 2.95 BS01 AMP F 1 F4 F26 D28 I29 L38 G88 Q89 E90 H95 H97 F4 F26 D28 I29 L38 G88 Q89 E90 H95 H97 ? 0003824,0005737,0005829,0043530,0055130 P64382 26750483 201 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSGD 4zgl H 2.95 BS01 AMP H 1 F4 D28 I29 N30 G88 Q89 E90 H95 H97 F4 D28 I29 N30 G88 Q89 E90 H95 H97 ? 0003824,0005737,0005829,0043530,0055130 P64382 26750483 201 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSG 4zgl I 2.95 BS01 AMP I 1 D28 I29 E90 H95 H97 D28 I29 E90 H95 H97 ? 0003824,0005737,0005829,0043530,0055130 P64382 26750483 201 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSGD 4zhx F 2.99 BS01 AMP F 1 R70 K170 I240 S242 F244 D245 R269 F273 L277 V297 R299 R45 K145 I215 S217 F219 D220 R244 F248 L252 V272 R274 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 26952388 401 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4zhx F 2.99 BS02 AMP F 2 H151 T200 I204 A205 V225 S226 I312 S314 S316 D317 H126 T175 I179 A180 V200 S201 I287 S289 S291 D292 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 26952388 402 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4zkl B 2.34 BS01 AMP B 1 D43 I44 N99 G105 Q106 S107 H112 H114 D31 I32 N87 G93 Q94 S95 H100 H102 3.4.22.-,3.9.1.- 0000118,0000166,0003824,0005080,0005515,0005634,0005654,0005737,0005829,0005856,0005886,0006355,0006508,0006915,0007165,0008234,0009154,0016787,0016926,0016929,0043530,0050850,0070062,0072332 P49773 26905466 201 PGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 4zkl D 2.34 BS02 AMP D 1 D43 I44 N99 G105 Q106 S107 H112 H114 D30 I31 N86 G92 Q93 S94 H99 H101 3.4.22.-,3.9.1.- 0000118,0000166,0003824,0005080,0005515,0005634,0005654,0005737,0005829,0005856,0005886,0006355,0006508,0006915,0007165,0008234,0009154,0016787,0016926,0016929,0043530,0050850,0070062,0072332 P49773 26905466 201 GGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 4zmf A 2.39 BS01 AMP A 1 A587 R592 K645 E713 L716 F720 A36 R41 K92 E156 L159 F163 2.7.11.7 0004674,0005524,0006468 Kd=110uM -logKd/Ki=3.96, Kd=110uM P42527 26260792 901 ISSETGEMGILWEFDPIINKWIRLSMKLKVERKPFAEGALREAYHTVSLGVGTDENYPLGTKLFPPIEMISPISKNNEAMTQLKNGTKFVLKLYKKEASRELYFEDVKMQMVCRDWGNKFNQKKPPKKIEFLMSWVVELIDRSPSSNGQPILCSIEPLLVGEFKKNNSNYGAVLTNRSTPQAFSHFTYELSNKQMIVVDIQGVDDLYTDPQIHTPDGKGFGLGNLGKAGINKFITTHKCNAVCALLDLDVK 4zmf B 2.39 BS01 AMP B 1 A587 R592 K645 E713 L716 F720 A36 R41 K94 E157 L160 F164 2.7.11.7 0004674,0005524,0006468 Kd=110uM P42527 26260792 901 ISSETGEMGILWEFDPIINKWIRLSMKLKVERKPFAEGALREAYHTVSLGVGTDENYPLGTTTKLFPPIEMISPISKNNEAMTQLKNGTKFVLKLYKKEAASRELYFEDVKMQMVCRDWGNKFNQKKPPKKIEFLMSWVVELIDRSPNGQPILCSIEPLLVGEFKKNNSNYGAVLTNRSTPQAFSHFTYELSNKQMIVVDIQGVDDLYTDPQIHTPDGKGFGLGNLGKAGINKFITTHKCNAVCALLDLDVK 4zxi A 2.9 BS03 AMP A 1 S626 G739 E740 A741 V760 Y761 D849 H861 R864 K952 S626 G735 E736 A737 V756 Y757 D845 H857 R860 K948 T625 V754 V869 F874 T625 V750 V865 F870 ? 0000166,0003824,0005737,0005829,0009058,0031177,0043041,0044550 A0A0X1KH98 26762461 1403 GHMNNLARLEPEVLSRHAISSEQLGIWYIQRLEPTCSAYNMVVAFDVKVNQSLGNKPIEILEAVMHDYPLLRVSMPANDQGIEQLIWDRVYPNIIFSDARHIEASDLTQLVEQDTKQPFDLTQPPLWRIHCYECGQNHYVIAFVIHHALMDFWSIGLLLRDVSKRFGLVAESDAVNGIEFVQYADKQQSSVIDDTDESLIFWKNALKHAPHVHSIPLDYPRPAVQQHKGSSLVFRVSESVSSGLVNLAKDYEITLFGLVLSGFYVLLHKLSNENNLVIATPVAGRLERSLRNALGQFVNTIAIHMDIDADQTLRQFTQQVQEQLRQSLKHQKIAFSRVVEAVSPKRDGSINPLAQIGMFWERLGGMDEFKELLLPIQTPATLVGQDLTLGSFPVRQQEGQLDITLEMGGEYQGELVGVLKYNTDLFSAQSAENMVQLLQAVLSEMVAHPERKIVELDIAPDYKDGIQFEALRGKATDYAQHDLFAMILKQIDERGDNHALTSHTVSYRELGQHIAGIAEYLRAHGITQGDRVGLMLDRTALLPAAILGIWAAGAAYVPLDPNFPTERLQNIIEDAEPKVILTQTELMDGLNVSVPRLDINQAGVVALEQVRETLAFGDIAYVMYTSKPKGVRIGHPSIINFLLSMNDRLQVTTETQLLAITTYAFDISILELLIPLMYGGVVHVCPREVSQDGIQLVDYLNAKSINVLQATPATWKMLLDSEWSGNAGLTALCGGEALDTILAEKLLGKVGCLWNVYGPTETTVWSSAARITDAKYIDLGEPLANTQLYVLDEQQRLVPPGVMGELWIGGDGLAVDYWQRPELTDAQFRTLPSLPNAGRLYRTGDKVCLRTDGRLTHHGRLDFQVKIRGFRIELGEIENVLKQIDGITDAVVLVKTTGDNDQKLVAYVTGQELDIAGLKKNLQIHLPAYMVPSAFIRLDEFPMTANKKLDRKAFPEPIFEQSNDYVAPRDPIEIELCTTFEQILSVKRVGIHDDFFELGGHSLLAVKLVNHLKKAFGTELSVALLAQYSTVERLGEIIRENKEIKPSIVIELRRGTYEQPLWLFHPIGGSTFCYMELSRHLNPNRTLRAIQSPGLIEADAAEVAIEEMATLYIAEMQKMQPQGPYFLGGWCFGGAIAYEISRQLRQMGQQVTGIVMIDTRAPIPENVPEDADDAMLLSWFARDLAAPYGKKLTIPAQYLRELSPDQMFDHVLKEAKAINVLPLDADPSDFRLYFDTYLANGIALQTYFPEPEDFPILLVKAKDEQEDFGESLGWDQLVKDTLTQVDLPGDHSSIMYAENVVAVAQTIDQMYPIP 5b6h A 1.9 BS01 AMP A 1 F32 R33 D131 L132 A134 T135 G136 T138 F26 R27 D125 L126 A128 T129 G130 T132 R70 E107 R64 E101 2.4.2.7 0003999,0005737,0005829,0006166,0006168,0009116,0016757,0044209 Q66DQ2 501 KTAQQLKYIKDSIKTIPDYPKAGILFRDVTSLLENPKAYSASIELLSEHYSESGVTKVVGTEARGFLFGAPVALALGVGFVPVRKPGKLPRETISESYELEYGTDTLEIHTDSIQPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVVHAAFIINLPELGGEARLTQQGIHCYSLVSFD 5b8h A 2.1999 BS03 AMP A 1 I83 R84 R86 Q89 I254 I82 R83 R85 Q88 I253 2.7.1.33 0004594,0005524,0005737,0015937,0016301,0016310 B4E9P3 304 SEPHLLIDAGNSRIKWALADARRTLVDTGAFGHTRDGGADPDWSRLPRPRGAWISNVAGADVAARIDALLDARWPGLPRTTIRSRPAQCGVTNGYTTPEQLGSDRWAGLIGAHAAFPGEHLLIATFGTATTLEALRADGCFTGGLIAPGWALMMRALGTHTAQLPTLTTDIASGLLAGAQAEPFQVDTPRSLSAGCLYAQAGLIERAWRDLVAAWQAPVRLVLAGGAADDVARALTIAHTRHDTLILSGLALIAAD 5bph A 1.7 BS01 AMP A 1 K97 I142 K144 M154 E180 W182 L183 E187 F209 Y210 M259 E270 K97 I142 K144 M154 E180 W182 L183 E187 F209 Y210 M259 E270 E15 V18 L21 H63 S150 D213 R255 D257 E270 N272 G276 H280 E15 V18 L21 H63 S150 D213 R255 D257 E270 N272 G276 H280 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q8ZIE7 26894530 401 MAEKVAVLLGGTSAEREVSLLSGQAVLAGLKEAGIDAYGVDTKDFPVTQLKEQGFDKVFIALHGRGGEDGTLQGVLEFLQLPYTGSGVMASALTMDKLRTKLVWQALGLPISPYVALNRQQFETLSPEELVACVAKLGLPLIVKPSHEGSSVGMSKVDHASELQKALVEAFQHDSDVLIEKWLSGPEFTVAILGDEVLPSIRIQPPGVFYDYDAKYLSDKTQYFCPSGLSDESEQQLAALALQAYHALDCSGWGRVDVMQDRDGHFYLLEVNTSPGMTSHSLVPMAARQYGLSFSQLVARILMLAD 5bph B 1.7 BS01 AMP B 1 K97 I142 K144 E180 W182 L183 E187 V208 Y210 M259 E270 K96 I141 K143 E179 W181 L182 E186 V207 Y209 M258 E269 E15 V18 L21 H63 S150 D213 Y216 R255 D257 E270 N272 G276 H280 E14 V17 L20 H62 S149 D212 Y215 R254 D256 E269 N271 G275 H279 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q8ZIE7 26894530 401 AEKVAVLLGGTSAEREVSLLSGQAVLAGLKEAGIDAYGVDTKDFPVTQLKEQGFDKVFIALHGRGGEDGTLQGVLEFLQLPYTGSGVMASALTMDKLRTKLVWQALGLPISPYVALNRQQFETLSPEELVACVAKLGLPLIVKPSHEGSSVGMSKVDHASELQKALVEAFQHDSDVLIEKWLSGPEFTVAILGDEVLPSIRIQPPGVFYDYDAKYLSDKTQYFCPSGLSDESEQQLAALALQAYHALDCSGWGRVDVMQDRDGHFYLLEVNTSPGMTSHSLVPMAARQYGLSFSQLVARILMLAD 5bph C 1.7 BS01 AMP C 1 K97 I142 K144 W182 L183 E187 Y210 M259 E270 K97 I142 K144 W182 L183 E187 Y210 M259 E270 E15 V18 L21 H63 S150 D213 Y216 R255 D257 E270 N272 G276 H280 E15 V18 L21 H63 S150 D213 Y216 R255 D257 E270 N272 G276 H280 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q8ZIE7 26894530 401 MAEKVAVLLGGTSAEREVSLLSGQAVLAGLKEAGIDAYGVDTKDFPVTQLKEQGFDKVFIALHGRGGEDGTLQGVLEFLQLPYTGSGVMASALTMDKLRTKLVWQALGLPISPYVALNRQQFETLSPEELVACVAKLGLPLIVKPSHEGSSVGMSKVDHASELQKALVEAFQHDSDVLIEKWLSGPEFTVAILGDEVLPSIRIQPPGVFYDYDAKYLSDKTQYFCPSGLSDESEQQLAALALQAYHALDCSGWGRVDVMQDRDGHFYLLEVNTSPGMTSHSLVPMAARQYGLSFSQLVARILMLAD 5bph D 1.7 BS01 AMP D 1 K97 I142 K144 E180 W182 L183 E187 Y210 M259 E270 K97 I142 K144 E179 W181 L182 E186 Y209 M256 E267 E15 V18 L21 H63 S150 D213 R255 D257 E270 N272 G276 H280 E15 V18 L21 H63 S149 D212 R252 D254 E267 N269 G273 H277 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q8ZIE7 26894530 401 MAEKVAVLLGGTSAEREVSLLSGQAVLAGLKEAGIDAYGVDTKDFPVTQLKEQGFDKVFIALHGRGGEDGTLQGVLEFLQLPYTGSGVMASALTMDKLRTKLVWQALGLPISPYVALNRQQFETLSPEELVACVAKLGLPLIVKPSHESSVGMSKVDHASELQKALVEAFQHDSDVLIEKWLSGPEFTVAILGDEVLPSIRIQPPGVFYDYDAKSDKTQYFCPSGLSDESEQQLAALALQAYHALDCSGWGRVDVMQDRDGHFYLLEVNTSPGMTSHSLVPMAARQYGLSFSQLVARILMLAD 5bsr A 1.5 BS02 AMP A 1 A309 G334 T336 D420 K437 K441 Q446 A301 G326 T328 D412 K429 K433 Q438 S189 S209 H237 T336 E337 K441 Q446 K526 S181 S201 H229 T328 E329 K433 Q438 K518 6.2.1.-,6.2.1.12,6.2.1.34 0003824,0005524,0009611,0009698,0009753,0016207,0016405,0016874,0050563,0106286,0106290 O24146 26412334 602 DIIFRSKLPDIYIPNHLPLHSYCFENISEFSSRPCLINGANKQIYTYADVELNSRKVAAGLHKQGIQPKDTIMILLPNSPEFVFAFIGASYLGAISTMANPLFTPAEVVKQAKASSAKIIVTQACHVNKVKDYAFENDVKIICIDSAPEGCLHFSVLTQANEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVSFLELIQRYKVTIGPFVPPIVLAIAKSPMVDDYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPKTGNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDKEGWLYTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFVDAIPKSPSGKILRKDLRAKL 5bu2 B 2.11 BS01 AMP B 1 K393 K396 E477 Y480 W481 S494 A495 K96 K99 E180 Y183 W184 S193 A194 26294765 701 DYLLSANGSKAIDFVWSNFLKHPYNPKLKQPDANVKAAWEKHADWEHWSNMGQDWSLNTPSGLVPRPNHGIAHTLRVAQLVPVIAEFLKAYSGDPKFQKLTQKEIQKAQYMMLFSVIGRENDMSWTDANHYQQAFKEAYNGQYSKHIYATFKENAQKGFLNHVVTNKSSLIPSLFSDESELQYWAEALDTISSASGILMALAHDLDLMRCYDKGKFNSLKMKDLVARLGGNEDAAKKLADYAHDLIVATGDRCMGYGVTQDYNYSLFGKCSLDPNECLKQLQSIPKPETT 5bu2 C 2.11 BS01 AMP B 1 K396 E477 Y480 S494 K99 E180 Y183 S193 26294765 701 DYLLSANGSKAIDFVWSNFLKHPYNPKLKQPDANVKAAWEKHADWEHWSNMGQDWSLNTPSGLVPRPNHGIAHTLRVAQLVPVIAEFLKAYSGDPKFQKLTQKEIQKAQYMMLFSVIGRENDMSWTDANHYQQAFKEAYNGQYSKHIYATFKENAQKGFLNHVVTNKSSLIPSLFSDESELQYWAEALDTISSASGILMALAHDLDLMRCYDKGKFNSLKMKDLVARLGGNEDAAKKLADYAHDLIVATGDRCMGYGVTQDYNYSLFGKCSLDPNECLKQLQSIPKPETT 5bus A 2.603 BS01 AMP A 1 H196 G264 G265 S285 M288 T289 D367 V379 R382 K471 H194 G262 G263 S283 M286 T287 D365 V377 R380 K467 T152 S172 H196 T289 E290 T150 S170 H194 T287 E288 6.2.1.26 0005524,0008756,0009234,0016405,0016874 P23971 26276389 503 TEQPNWLMQRAQLTPERIALIYEDQTVTFAELFAASKRMAEQLAAHSVRKGDTAAILLQNRAEMVYAVHACFLLGVKAVLLNTKLSTHERLFQLEDSGSGFLLTDSSFEKKEYEHIVQTIDVDELMKEAAEEIEIEAYMQMDATATLMYTSGTTGKPKGVQQTFGNHYFSAVSSALNLGITEQDRWLIALPLFHISGLSALFKSVIYGMTVVLHQRFSVSDVLHSINRHEVTMISAVQTMLASLLEETNRCPESIRCILLGGGPAPLPLLEECREKGFPVFQSYGMTETCSQIVTLSPEFSMEKLGSAGKPLFSCEIKIERDGQVCEPYEHGEIMVKGPNVMKSYFNRESANEASFQNGWLKTGDLGYLDNEGFLYVLDRRSDLIISGGENIYPAEVESVLLSHPAVAEAGVSGAEDKKKVPHAYLVLHKPVSAGELTDYCKERLAKYKIPAKFFVLDRLPRNASNKLLRNQLKDARKGEL 5bus B 2.603 BS01 AMP B 1 G264 M288 T289 D367 G260 M283 T284 D362 T152 S172 H196 T289 E290 T150 S170 H194 T284 E285 6.2.1.26 0005524,0008756,0009234,0016405,0016874 P23971 26276389 503 TEQPNWLMQRAQLTPERIALIYEDQTVTFAELFAASKRMAEQLAAHSVRKGDTAAILLQNRAEMVYAVHACFLLGVKAVLLNTKLSTHERLFQLEDSGSGFLLTDSSFEKKEYEHIVQTIDVDELMKEAAEEIEIEAYMQMDATATLMYTSGTTGKPKGVQQTFGNHYFSAVSSALNLGITEQDRWLIALPLFHISGLSALFKSVIYGMTVVLHQRFSVSDVLHSINRHEVTMISAVQTMLASLLEETCPESIRCILLGGGPPLPLLEECREKGFPVFQSYGMTETCSQIVTLSPEFSMEKLGSAGKPLFSCEIKIERDGQVCEPYEHGEIMVKGPNVMKSYFNRESANEASFQNGWLKTGDLGYLDNEGFLYVLDRRSDL 5byf A 2.0 BS01 AMP A 1 T235 G237 A238 G240 N295 A298 T223 G225 A226 G228 N283 A286 G266 A267 G268 D269 G254 A255 G256 D257 2.7.1.15 0004747,0005515,0005524,0005634,0005737,0005829,0006014,0006098,0006753,0016301,0016310,0019303,0042802,0046835,0046872 Q9H477 401 EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDLPLTLFLEH 5byf B 2.0 BS01 AMP B 1 T235 G237 A238 A267 G268 N295 A298 T222 G224 A225 A254 G255 N282 A285 G266 A267 G268 D269 G253 A254 G255 D256 2.7.1.15 0004747,0005515,0005524,0005634,0005737,0005829,0006014,0006098,0006753,0016301,0016310,0019303,0042802,0046835,0046872 Q9H477 401 EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDLPLTLFLEH 5ck7 A 2.99 BS01 AMP A 1 N324 H381 T382 L383 A409 A413 V468 C469 L478 G479 N277 H334 T335 L336 A362 A366 V421 C422 L431 G432 2.7.1.147 0005576,0005975,0006006,0006096,0016301,0016310,0016773,0043843,0046872 Q8VDL4 26555263 601 KLALSPESRLAAAWDALIAQPARRWRRVAVGVNACVDVVISGVKLLQALGLSPGSGKDHAILHSRSDLEEAFLYFMGKGAAAERFFSDKETFHDIAQAASEFPGAQHYVGGNAALIGQRFAANTDLKVLLCGPIGPKLHELLDDNVFVPPESLQEEDEFHLILEYLAGEEWGPFKAPHANRFIFSHDLSNGAMNMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKELQRKRLLEVVTAISDIPTGIPVHLELASMTNRELMSSIVHQVFPAVASLGLNEQELLFLSQSASGPHSSLSSWDGVPDVGMVSDILFWILKEHGRSENRSSDLTRIHFHTLVYHILATVDGHWANQLAAVAAGARVAGTQACATETIDTNRVSLRAPQEFTTSHLESGSRIVLNPDKPVVEWHREGITFHFTPVLVCKDPVRTVGLGDAISAEGLFYSEARPD 5cot A 1.69 BS01 AMP A 1 T145 T168 V169 K170 L171 S175 E227 F248 V315 K317 K326 T146 T169 V170 K171 L172 S176 E228 F249 V316 K318 K327 ? 0005524,0046872 D2W2Z5 26512110 401 SMGVRKLATIRTAGEITPIAGAEAIECCHVDGWTCVIKKGEFKQGDRGVYFEIDSFIKEDNDRYPMLSKQVIDYEGQRGTRLRTARLRGQLSQGLFLPMDRFPELASNQVGDDVTEILGITKWEPPISTNLSGEILGEFPTFISKTDQERVQNLIPQIEENKGQKFEVTVKLDGSSMTVYRKDDHIGVCGRNWELRETATNAQWHAARRNKMIEGLQFLNRNLALQGEIIGESIQGNLEKLKGQDFYLFDIYDIDKAQYLTPIERQSLVKQLNDNGFTVKHVPILDDLELNHTAEQILAMADGPSLNKNVKREGLVFKRLDGKFSFKAISNAYLEKHKDR 5d0n A 3.2 BS01 AMP A 1 S144 D145 G146 T147 G148 T150 T204 P248 R249 S14 D15 G16 T17 G18 T20 T74 P118 R119 2.7.11.32,2.7.4.27 0000166,0004674,0005524,0009507,0009570,0016310,0016772,0016776 Q195N6 26620526 501 DVCEAAGKAIYIVSDGTGWTAEHSVNAALGQFENCLADRGCAVNTHLFSLIDDMDRLIEVIKQAAKEGALVLYTLADPSMAEATKKACDFWGVPCTDVLRPTVEAIASHIGVAPSGIPRSSPSRNGRLSEDYFQRIDAIDFTIKQDDGALPQNLYRADIVLAGVSRTGKTPLSIYLAQKGYKVANVPIVMGVDLPKSLFEINQDKVFGLTINPAIEMDHVRQELVHANQIFAQNPSWPVIAVTGKAIEETAAVILGILHDRKQKCSMPRISKRY 5d1f A 3.4 BS01 AMP A 1 S144 D145 T147 G148 T150 T204 P248 R249 S14 D15 T17 G18 T20 T74 P118 R119 2.7.11.32,2.7.4.27 0000166,0004674,0005524,0009507,0009570,0016310,0016772,0016776 Q195N6 26620526 501 DVCEAAGKAIYIVSDGTGWTAEHSVNAALGQFENCLADRGCAVNTHLFSLIDDMDRLIEVIKQAAKEGALVLYTLADPSMAEATKKACDFWGVPCTDVLRPTVEAIASHIGVAPSGIPRSSPSRNGRLSEDYFQRIDAIDFTIKQDDGALPQNLYRADIVLAGVSRTGKTPLSIYLAQKGYKVANVPIVMGVDLPKSLFEINQDKVFGLTINPAIEMDHVRQELVHANQIFAQNPSWPVIAVTGKAIEETAAVILGILHDRKQKCSMPRISKRY 5d4n A 1.6 BS02 AMP B 1 G35 Y36 T37 A69 K105 F106 G33 Y34 T35 A67 K103 F104 ? 0000166,0006808,0030234 D5X329 27464895 201 AIKLYPLKKLEIILEGAHKEFATDLLDRAGVKGYTIVGNLSGKGSHGMYEGHLMFNEDDALIMIIAAVPEELVGPLLEGFQPFFEAHSGVVFVHDIQVGRPIKFR 5d4n B 1.6 BS01 AMP B 1 K45 G46 S47 Y51 L63 S90 G91 K42 G43 S44 Y48 L50 S77 G78 ? 0000166,0006808,0030234 D5X329 27464895 201 IKLYPLKKLEIILEGAHKEFATDLLDRAGVKGYTIVGNLSGKGSHGMYALIMIIAAVPEELVGPLLEGFQPFFEAHSGVVFVHDIQVGRP 5d4o A 1.8 BS03 AMP A 1 G35 Y36 T37 A69 K105 F106 G33 Y34 T35 A67 K103 F104 ? 0000166,0006808,0030234 D5X329 27464895 203 AIKLYPLKKLEIILEGAHKEFATDLLDRAGVKGYTIVGNLSGKGSHGMYEGHLMFNEDDALIMIIAAVPEELVGPLLEGFQPFFEAHSGVVFVHDIQVGRPIKFRN 5d4o B 1.8 BS01 AMP A 1 K45 G46 S47 Y51 L63 S90 G91 K41 G42 S43 Y47 L49 S76 G77 ? 0000166,0006808,0030234 D5X329 27464895 203 KLYPLKKLEIILEGAHKEFATDLLDRAGVKGYTIVGNLSGKGSHGMYALIMIIAAVPEELVGPLLEGFQPFFEAHSGVVFVHDIQVGRPI 5djh A 1.451 BS03 AMP A 1 D94 S162 R165 G185 S186 K190 H204 G206 G207 Q208 D212 D89 S147 R150 G170 S171 K175 H189 G191 G192 Q193 D197 3.1.3.11,3.1.3.25,3.1.3.7 0000103,0000287,0005515,0005886,0008441,0008934,0016787,0030145,0042132,0046872,0050427,0050897,0052832,0052833,0052834 P9WKJ1 26512869 304 HHHHHDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFSTPGRDDWAVHIALWRRSPEITDAAVALPARGNVVYRTDTVTSVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPYLPDLLMCRAEVAPILLGAIADAWR 5dji A 1.659 BS03 AMP A 1 D94 S162 R165 G185 S186 K190 H204 G206 G207 Q208 D212 D90 S147 R150 G170 S171 K175 H189 G191 G192 Q193 D197 3.1.3.11,3.1.3.25,3.1.3.7 0000103,0000287,0005515,0005886,0008441,0008934,0016787,0030145,0042132,0046872,0050427,0050897,0052832,0052833,0052834 P9WKJ1 26512869 303 HHHHHSDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFSTPGRDDWAVHIALWRRSSEITDAAVALPARGNVVYRTDTVTSPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPYLPDLLMCRAEVAPILLGAIADAWR 5drk A 2.38 BS01 AMP B 1 G44 K45 G46 S47 L63 S90 G41 K42 G43 S44 L51 S78 ? 0000166,0006808,0030234 D5X329 27464895 201 IKLYPLKKLEIILEGAHKEFATDLLDRAGVKGYTIVGNLSGKGSHGMYEALIMIIAAVPEELVGPLLEGFQPFFEAHSGVVFVHDIQVG 5drk B 2.38 BS01 AMP B 1 G35 Y36 T37 A69 K105 G33 Y34 T35 A67 K103 ? 0000166,0006808,0030234 D5X329 27464895 201 AIKLYPLKKLEIILEGAHKEFATDLLDRAGVKGYTIVGNLSGKGSHGMYEGHLMFNEDDALIMIIAAVPEELVGPLLEGFQPFFEAHSGVVFVHDIQVGRPIKFR 5ds7 A 2.0 BS01 AMP A 1 G35 Y36 T37 A69 G32 Y33 T34 A57 ? 0000166,0006808,0030234 D5X329 27464895 201 IKLYPLKKLEIILEGAHKEFATDLLDRAGVKGYTIVGNLSGKGSHGMYEALIMIIAAVPEELVGPLLEGFQPFFEAHSGVVFVHDIQVGRP 5ds7 A 2.0 BS02 AMP B 1 K45 G46 S47 Y51 L63 S90 G91 K42 G43 S44 Y48 L51 S78 G79 ? 0000166,0006808,0030234 D5X329 27464895 201 IKLYPLKKLEIILEGAHKEFATDLLDRAGVKGYTIVGNLSGKGSHGMYEALIMIIAAVPEELVGPLLEGFQPFFEAHSGVVFVHDIQVGRP 5ds7 B 2.0 BS01 AMP B 1 G35 Y36 T37 A69 F106 G33 Y34 T35 A67 F104 ? 0000166,0006808,0030234 D5X329 27464895 201 AIKLYPLKKLEIILEGAHKEFATDLLDRAGVKGYTIVGNLSGKGSHGMYEGHLMFNEDDALIMIIAAVPEELVGPLLEGFQPFFEAHSGVVFVHDIQVGRPIKFR 5ds7 B 2.0 BS02 AMP C 1 G44 K45 G46 S47 H48 L63 S90 G42 K43 G44 S45 H46 L61 S88 ? 0000166,0006808,0030234 D5X329 27464895 201 AIKLYPLKKLEIILEGAHKEFATDLLDRAGVKGYTIVGNLSGKGSHGMYEGHLMFNEDDALIMIIAAVPEELVGPLLEGFQPFFEAHSGVVFVHDIQVGRPIKFR 5ds7 C 2.0 BS01 AMP A 1 G44 K45 S47 H48 S90 G91 G41 K42 S44 H45 S77 G78 ? 0000166,0006808,0030234 D5X329 27464895 201 IKLYPLKKLEIILEGAHKEFATDLLDRAGVKGYTIVGNLSGKGSHGMYALIMIIAAVPEELVGPLLEGFQPFFEAHSGVVFVHDIQVGRPIKFR 5ds7 C 2.0 BS02 AMP C 1 G35 Y36 T37 A69 K105 F106 G32 Y33 T34 A56 K92 F93 ? 0000166,0006808,0030234 D5X329 27464895 201 IKLYPLKKLEIILEGAHKEFATDLLDRAGVKGYTIVGNLSGKGSHGMYALIMIIAAVPEELVGPLLEGFQPFFEAHSGVVFVHDIQVGRPIKFR 5dy9 A 1.6 BS01 AMP A 1 N16 N47 Y48 N1 N32 Y33 ? 0003723,0006355 Q58830 27187760 101 NFEYARRLNGKKVKIFLRNGEVLDAEVTGVSNYEIMVKVGDRNLLVFKHAIDTIEY 5dy9 D 1.6 BS01 AMP E 1 Y48 F62 H64 Y33 F47 H49 ? 0003723,0006355 Q58830 27187760 101 NFEYARRLNGKKVKIFLRNGEVLDAEVTGVSNYEIMVKVGDRNLLVFKHAIDTIEY 5dy9 E 1.6 BS01 AMP E 1 E18 N47 K63 E7 N36 K52 ? 0003723,0006355 Q58830 27187760 101 KVIPNFEYARRLNGKKVKIFLRNGEVLDAEVTGVSNYEIMVKVGDRNLLVFKHAIDTIEY 5dy9 F 1.6 BS01 AMP A 1 Y48 H64 Y35 H51 ? 0003723,0006355 Q58830 27187760 101 IPNFEYARRLNGKKVKIFLRNGEVLDAEVTGVSNYEIMVKVGDRNLLVFKHAIDTIEY 5dy9 G 1.6 BS01 AMP G 1 E18 N47 Y48 E3 N32 Y33 ? 0003723,0006355 Q58830 27187760 101 NFEYARRLNGKKVKIFLRNGEVLDAEVTGVSNYEIMVKVGDRNLLVFKHAIDTIEY 5dy9 L 1.6 BS01 AMP G 1 Y48 H64 Y34 H50 ? 0003723,0006355 Q58830 27187760 101 PNFEYARRLNGKKVKIFLRNGEVLDAEVTGVSNYEIMVKVGDRNLLVFKHAIDTIEY 5dyj A 2.5 BS02 AMP A 1 F586 A587 G589 K645 E713 L716 F720 D766 F35 A36 G38 K94 E162 L165 F169 D215 2.7.11.7 0004674,0005524,0006468 P42527 27211275 904 ISSETGEMGILWEFDPIINKWIRLSMKLKVERKPFAEGALREAYHTVSLGVGTDENYPLGTTTKLFPPIEMISPISKNNEAMTQLKNGTKFVLKLYKKEAEQQASRELYFEAVKMQMVCRDWGNKFNQKKPPKKIEFLMSWVVELIDRSPSSNGQPILCSIEPLLVGEFKKNNSNYGAVLTNRSTPQAFSHFTYELSNKQMIVVDIQGVDDLYTDPQIHTPDGKGFGLGNLGKAGINKFITTHKCNAVCALLDLDVKL 5dyj B 2.5 BS02 AMP B 1 A587 E588 G589 K645 E713 L716 F720 D766 A36 E37 G38 K94 E157 L160 F164 D210 2.7.11.7 0004674,0005524,0006468 P42527 27211275 904 ISSETGEMGILWEFDPIINKWIRLSMKLKVERKPFAEGALREAYHTVSLGVGTDENYPLGTTTKLFPPIEMISPISKNNEAMTQLKNGTKFVLKLYKKEAEQQASRELYFEAVKMQMVCRDWGNKFNQKKPPKKIEFLMSWVVELIDRSPPILCSIEPLLVGEFKKNNSNYGAVLTNRSTPQAFSHFTYELSNKQMIVVDIQGVDDLYTDPQIHTPDGKGFGLGNLGKAGINKFITTHKCNAVCALLDLDVKL 5dzt A 2.2 BS02 AMP A 1 Q250 V272 K274 E312 E313 Y314 I315 D364 Q232 V254 K256 E294 E295 Y296 I297 D346 ? 0000166,0005975,0031179,0046872 Q8KUA3 26226635 1002 NLINVLSINERCFLLKQSGNEKYDIKNLQAWKERKSVLKQDDLDYLIKYKYESLDNFGLGITPIENFPDKEVAIQYIKDQSWYIFFESILDSYNDSEEQLLEVDASYPFRYFLQYARLFLLDLNSELNICTKEFIINLLEILTQELIHLTSKTLVLDLHRFIYYLKKRFNSKKDIIAFYTCYPELMRITVVRMRYFLDNTKQMLIRVTEDLPSIQNCFNIQSSELNSISESQGDSHSRGKTVSTLTFSDGKKIVYKPKINSENKLRDFFEFLNKELEADIYIVKKVTRNTYFYEEYIDNIEINNIEEVKKYYERYGKLIGIAFLFNVTDLHYENIIAHGEYPVIIDNETFFQQNIPIEFGNSATVDAKYKYLDSIMVTGLVPKNTPIMNNEKISFISYEKYIVTGMKSILMKAKDSKKKILAYINNNLQNLIVRNVIRPTQRYADMLEFSYHPNCFSNAIEREKVLHNMWAYPYKNKKVVHYEFSDLIDGDIPIFYNNISKTSLIASDGCLVEDFYQESALNRCLNKINDLCDEDISIQTVWLEIALNIYNPYKYINDLKNQNSNKYIYTGLELNGKIIQACQKIEKKIFKRAIFNKKTNTVNWIDIKLDQDWNVGILNNNMYDGLPGIFIFYVALKYITKNHKYDYVIECIKNSIYTIPSEDILSAFFGKGSLIYPLLVDYRLNNDINSLNVAVEIADMDWIHGHNSIIKVLLLLSEITEDEKYRKFSLEIFEKLSEEPYFNFRGFGHGIYSYVHLLSKFNRIDKANSLLHKIKNNSWCKGTVGELLATDINKTIEYKNKDCLCHGNAGTLEGLIQLAKKDPETYQYKKNKLISYMLKYFEKNNTLKVAGSEYLESLGFFVGISGVGYELLRNLDSEIPNALLFE 5e7j A 2.23 BS01 AMP A 1 Y200 T204 Q207 G227 S228 G229 K230 T231 Y57 T61 Q64 G84 S85 G86 K87 T88 3.6.4.13 0003676,0003724,0005524 O00571 26598523 801 EDDWSKPLPPSERLEQELFSGGIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSS 5ed3 B 1.309 BS01 AMP B 1 D43 I44 Q106 S107 V108 H112 H114 D32 I33 Q95 S96 V97 H101 H103 3.4.22.-,3.9.1.- 0000118,0000166,0003824,0005080,0005515,0005634,0005654,0005737,0005829,0005856,0005886,0006355,0006508,0006915,0007165,0008234,0009154,0016787,0016926,0016929,0043530,0050850,0070062,0072332 P49773 31604935 201 RPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 5ed6 B 1.52 BS01 AMP B 1 I18 D43 I44 N99 Q106 S107 H112 I7 D32 I33 N88 Q95 S96 H101 3.4.22.-,3.9.1.- 0000118,0000166,0003824,0005080,0005515,0005634,0005654,0005737,0005829,0005856,0005886,0006355,0006508,0006915,0007165,0008234,0009154,0016787,0016926,0016929,0043530,0050850,0070062,0072332 P49773 31604935 201 RPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLAVLGGRQMHWPPG 5ers A 1.7 BS01 AMP A 1 E509 L510 D524 S525 N526 G572 G573 G626 N627 P628 E191 L192 D206 S207 N208 G254 G255 G308 N309 P310 2.10.1.1,2.7.7.75 0006777,0032324 Kd=2mM Q03555 27112598 801 SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 5et6 A 1.845 BS01 AMP A 1 K20 G21 A24 T27 E29 L30 K112 Y113 T177 K13 G14 A17 T20 E22 L23 K99 Y100 T161 D74 E97 E98 D118 L120 D121 E280 D61 E84 E85 D105 L107 D108 E264 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 O00757 27050133 401 TDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGSVVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQA 5et6 B 1.845 BS01 AMP B 1 V17 K20 G21 A24 G26 T27 E29 L30 K112 Y113 T177 V9 K12 G13 A16 G18 T19 E21 L22 K97 Y98 T158 D74 E97 E98 D118 L120 D121 E280 D59 E82 E83 D103 L105 D106 E261 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 O00757 27050133 401 DMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGSVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKN 5et6 C 1.845 BS01 AMP C 1 V17 K20 G21 A24 T27 E29 L30 K112 Y113 R140 T177 V9 K12 G13 A16 T19 E21 L22 K97 Y98 R125 T159 D74 E97 E98 D118 L120 D121 E280 D59 E82 E83 D103 L105 D106 E262 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 O00757 27050133 401 DMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGSVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQ 5et6 D 1.845 BS01 AMP D 1 V17 K20 G21 A24 G26 T27 E29 L30 K112 Y113 T177 V9 K12 G13 A16 G18 T19 E21 L22 K97 Y98 T158 D74 E97 E98 D118 L120 D121 E280 D59 E82 E83 D103 L105 D106 E261 3.1.3.11 0005515,0005634,0005737,0005829,0005886,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0030018,0030388,0042132,0042578,0042802,0046872,0070062,0070161 O00757 27050133 401 DMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGSVKKLDVLSNSLVINMLQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKN 5eyt A 2.3649 BS01 AMP A 1 R14 Y15 R298 R12 Y13 R290 H80 T152 H153 K290 E297 H78 T150 H151 K282 E289 4.3.2.2 0000166,0003824,0004018,0005829,0006164,0006189,0009152,0009168,0016829,0044208,0070626 G4VQX9 28347672 1000 EFEEYRNPLTKRYASREMVCNFGEKRKVILWRQLWIWLAETQKELGFDITDEQINEMKSQRDSVDFGTAAAEEKARRHDVMAHVYTFALACPKAAPIIHLGATSCFVGDNADLIMLKDGLNILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLERLKNHTIRFRGAKGAVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVTGQTYPRKVDIEITNALSNIGATVHKICTDIRLLSSFHEVEEPFETKMPYKRNPIRSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLTLLQNIAEGLIVYPMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAAAEIKLKGLKNSLMDKLLNDYYFAPIHSLLPTVLDPSYMIGRAVEQVEVFLNTEVDPAIHSYKDCLALNSNITI 5f1f A 1.548 BS01 AMP A 1 S65 Q121 Y151 Y223 G314 S315 T316 S67 Q123 Y153 Y225 G316 S317 T318 S65 K68 M107 E109 F122 Y151 G157 E272 K312 S315 S67 K70 M109 E111 F124 Y153 G159 E274 K314 S317 3.5.2.6 0000166,0008800,0016787,0017001,0030288,0046677,0046872 Q99QC1 27999057 407 HHGEASPVDPLRPVVDASIQPLLKEHRIPGMAVAVLKDGKAHYFNYGVANRESGAGVSEQTLFEIGSVSKTLTATLGAYAVVKGAMQLDDKASRHAPWLKGSAFDSITMGELATYSAGGLPLQFPEEVDSSEKMRAYYRQWAPVYSPGSHRQYSNPSIGLFGHLAASSLKQPFAPLMEQTLLPGLGMHHTYVNVPKQAMASYAYGYSKEDKPIRVNPGMLADEAYGIKTSSADLLRFVKANIGGVDDKALQQAISLTHQGHYSVGGMTQGLGWESYAYPVTEQTLLAGNSAKVILEANPTAAPRESGSQVLFNKTGSTNGFGAYVAFVPARGIGIVMLANRNYPIEARIKAAHAILAQLAG 5f1g A 1.76 BS01 AMP A 1 S61 Q117 D120 Y147 N149 Y218 G316 A317 T318 S62 Q118 D121 Y148 N150 Y219 G307 A308 T309 S61 K64 Y109 A111 V118 Y147 G153 E269 K314 A317 S62 K65 Y110 A112 V119 Y148 G154 E270 K305 A308 3.5.2.6 0000166,0008800,0016787,0017001,0030288,0046677 A7TUE6 27999057 401 HHPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPATKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPPEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVRSNMNPRDINDKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINAAHPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVAAAWQILNALQ 5f5x A 2.006 BS01 AMP A 1 G89 A116 R179 E181 W182 E246 H313 G90 A117 R180 E182 W183 E247 H314 ? 0000166,0016787 Q734X3 501 AMLIKPKRLQAGDIVATVSPSWGGAGDSEIRWRYEQGVKRLEEVFGLTVVPMPNSLKGSEFIYNNPQARAEDLMTAFQDTRVKAIIANIGGQDSIRLLPYIDFNAIRENPKIFMGYADVTISHLFCHKAGLSSFYGPAILTDFAENVEMDPYTVEMVNRTLFSNEMIGEIQPAPEWTSERLEWIEINKDTRRTMQQNNGYELLQGSTTVQGRLIGGCIEVLEFAKGTELWPEKKHWEDSILFFETSEDHPEPSYIKYWLRNYAAQGILQKAKGIIFGKPKDEMYYEEYKHEILQVMKEHNLEDLPILYNLNFGHTEPKFILPYGSMAEIDCENGSFSILESGVE 5f5x B 2.006 BS01 AMP B 1 G89 A116 R179 L180 E181 W182 E246 H313 G90 A117 R180 L181 E182 W183 E247 H314 ? 0000166,0016787 Q734X3 501 AMLIKPKRLQAGDIVATVSPSWGGAGDSEIRWRYEQGVKRLEEVFGLTVVPMPNSLKGSEFIYNNPQARAEDLMTAFQDTRVKAIIANIGGQDSIRLLPYIDFNAIRENPKIFMGYADVTISHLFCHKAGLSSFYGPAILTDFAENVEMDPYTVEMVNRTLFSNEMIGEIQPAPEWTSERLEWIEINKDTRRTMQQNNGYELLQGSTTVQGRLIGGCIEVLEFAKGTELWPEKKHWEDSILFFETSEDHPEPSYIKYWLRNYAAQGILQKAKGIIFGKPKDEMYYEEYKHEILQVMKEHNLEDLPILYNLNFGHTEPKFILPYGSMAEIDCENGSFSILESGVE 5f74 A 2.35 BS02 AMP A 1 K51 R58 K122 R129 N175 K50 R57 K119 R126 N172 ? 0004860,0005515,0005634,0005737,0005829,0006605,0019899,0019904,0035308,0042470,0042802,0042826,0043085,0045184,0045744,0048471,0050815,0051219,0051220 Kd=7.6uM -logKd/Ki=5.12, Kd=7.6uM Q9CQV8 26984404 301 TMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLILNATQAESKVFYLKMKGDYFRYLSEVASGENKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTS 5f9y A 2.8 BS02 AMP A 1 I341 R342 T343 F346 Q416 T453 R455 I153 R154 T155 F158 Q228 T265 R267 E302 R331 H352 E114 R143 H164 0000166,0004812,0004827,0005524,0005737,0006418,0006433 701 AHHHHHHSKENESLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETSPEVAWVTKSSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARLAMKSLCIPNDQIFKIEEGKTKCFFCDKLAKKFTLFGRSY 5f9y B 2.8 BS02 AMP B 1 I341 R342 T343 F346 T419 T453 R455 I138 R139 T140 F143 T216 T250 R252 E302 R331 H352 E99 R128 H149 0000166,0004812,0004827,0005524,0005737,0006418,0006433 701 SLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLEEVAWVTKSSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARGAMKSLCIPNDQIFTKCFFCDKLAKKFTLFGRSY 5fbb A 1.75 BS05 AMP A 1 F81 D83 L144 A151 G152 H168 F61 D63 L124 A131 G132 H148 W21 H26 D65 K68 H80 H135 D139 H145 H168 D172 W1 H6 D45 K48 H60 H115 D119 H125 H148 D152 3.1.30.1 0003676,0004518,0004519,0005575,0006308,0016788,0046872 P24021 28036383 701 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fbb B 1.75 BS05 AMP B 1 F81 D83 L144 A151 G152 H168 F61 D63 L124 A131 G132 H148 W21 H26 D65 K68 H80 H135 D139 H145 H168 D172 W1 H6 D45 K48 H60 H115 D119 H125 H148 D152 3.1.30.1 0003676,0004518,0004519,0005575,0006308,0016788,0046872 P24021 28036383 701 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fcb A 1.55 BS03 AMP A 1 H111 N148 H149 Y257 H290 H92 N129 H130 Y238 H271 3.1.4.-,3.6.1.15 0004767,0005576,0005615,0006685,0008081,0008150,0008270,0009143,0016787,0016887,0046872,0160049 P70158 26792860 516 HKLVPLAPADRAPAVGQFWHVTDLHLDPTYHITDDRTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTGTVIKVITNMTMTVQNLFPNLQVFPALGNHDYWPQDQLPIVTSKVYSAVADLWKPWLGEEAISTLKKGGFYSQKVASNPGLRIISLNTNLYYGPNIMTLNKTDPANQFEWLENTLNSSLWNKEKVYIIAHVPVGYLPYATDTPAIRQYYNEKLLDIFRRYSSVIAGQFYGHTHRDSLMVLSDKNGNPLNSVFVAPAVTPVKGVLQKETNNPGVRLFQYKPGDYTLLDMVQYYLNLTEANLKGESNWTLEYVLTQAYSVADLQPKSLYALVQQFATKDSKQFLKYYHYYFVSYDSSATCDQHCKTLQVCAIMNLDSMSYDDCLKQHL 5g40 A 1.69 BS03 AMP A 1 T31 G32 F35 R36 M53 E57 V59 T64 G85 R88 Q92 R160 T31 G32 F35 R36 M53 E57 V59 T64 G85 R88 Q92 R160 0004017,0005524,0006139,0016776,0019205 28008087 1218 MNLVLMGLPGAGKGTQAEKIVEKYGIPHISTGDMFRAAIKEGTELGLKAKSFMDKGELVPDEVTIGIVRERLSKDDCKKGFLLDGFPRTVAQAEALDNILSELGKKLDYVINIEVPKEELMERLTGRRICKTCGATYHLIFNPPKVEGICDKDGGELYQRADDNPETVANRLDVNMKQTQPLLDFYEEKGVLRNIDGQQDINKVFADIKALLGGL 5g5x A 2.8 BS01 AMP A 1 V242 V243 H263 F266 R323 I335 S337 D340 V8 V9 H29 F32 R89 I101 S103 D106 3.4.24.85 O29915 28502790 1354 MDVMNTEVVTVTPEMTVSEVIDLILKTKHLGFPVVEGERLVGIITLHDIIGVEPEERVGNIMSREVVAVSPNQSAFEAFKIMSEMGIGRLPVVEHGRVVGIVSRSDLMRIKEILEALEV 5gju A 1.6 BS01 AMP A 1 Y26 Q33 T52 G53 G55 K56 T57 Y21 Q28 T47 G48 G50 K51 T52 3.6.4.13 0003676,0003724,0005524 P0A9P6 29107486 301 TTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMRGVNVVALYVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADEMLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRI 5gmd A 1.5 BS03 AMP A 1 R22 G23 K155 E157 E159 R22 G23 K155 E157 E159 4.1.1.33 0004163,0005524,0005829,0008299,0016829,0016831,0019287 Q97UL5 28003359 1003 MLKSVTVSAPSNIAVVKYWGKRGDERLNLPLNNSLSITLDDQLSVITKVTLNDKNIVIVNDRILSEDEMKEYAGRVLDTFKKIVGKEFHVKVESKSKFPINAGLASSAAGIAALAFSLNELLELNLKSEELSKIARLGSGSACRSMFGGFVVWNKGEREDGEDSYCYQIFRHDYWSELVDIIPILSEKEKKISSRKGMIRSAETSELMECRLKYIEKTFNEVIEAIRNRDEKKFYYLMMRHSNSMHAVILDSWPSFFYLNDTSIRIMEWIHDYGKAGYTFDAGPNPHIFTTERNIGDILEFLKSLEIKRIIVSKVGDGPKVLSRE 5gme A 1.7 BS03 AMP A 1 R22 G23 K155 E157 E159 R21 G22 K154 E156 E158 4.1.1.33 0004163,0005524,0005829,0008299,0016829,0016831,0019287 Q97UL5 28003359 1003 LKSVTVSAPSNIAVVKYWGKRGDERLNLPLNNSLSITLDDQLSVITKVTLNDKNIVIVNDRILSEDEMKEYAGRVLDTFKKIVGKEFHVKVESKSKFPINAGLASSAAGIAALAFSLNELLELNLKSEELSKIARLGSGSACRSMFGGFVVWNKGEREDGEDSYCYQIFRHDYWSELVDIIPILSEKEKKISSRKGMIRSAETSELMECRLKYIEKTFNEVIEAIRNRDEKKFYYLMMRHSNSMHAVILDSWPSFFYLNDTSIRIMEWIHDYGKAGYTFDAGPNPHIFTTERNIGDILEFLKSLEIKRIIVSKVGDGPKVLSRE 5gxd A 2.001 BS01 AMP A 1 G365 E366 R367 H387 W388 W389 Q390 T391 D478 I490 R493 N499 R504 G364 E365 R366 H386 W387 W388 Q389 T390 D477 I489 R492 N498 R503 T239 T391 E392 N499 R504 K588 T238 T390 E391 N498 R503 K587 6.2.1.- 0000166,0016874,0050218 A8LRC0 701 TYSQTYAAWKNDPEGFWMEAAQAIDWVTPPGAALNSDNAPLYEWFTDAEVNTCFNAVDRHVQAGNGDRVAIIHDSPVTHTKQEITYAELQERVSLLAGALRAKGIEKGDRVLIYMPMVPQALEAMLACARLGAIHSVVFGGFAANELAVRIDDATPKAIIAASCGIEPGRVVHYKPLLDGAIDLATHKPDFCLIFQREQEVAHLEPGRDFDWHEAQYGVDPAECVPVAGNHPAYILYTSGTTGQPKGVLRPTAGHLVALNWTMKNIYNVDPGDVFWAASDVGWVVGHSYICYAPLIHGNTTIVFEGKPVGTPDAGTFWRVISEHKVKSFFTAPTALRAVKREDPNGEFIGKYDLSHLKTVYLAGERADPDTIQWTMDKLGVPVIDHWWQTETGWAIAANPMGIEHLPVKIGSPSVAMPGYDVQVLDEGGHPVAPGTLGAIAVKLPLAPGTLPNLWQAEERFVKSYLTTFPGYYETGDAGYIDEDGYLYIMARTDDVINVAGHRLSTGAMEEVLASHPDVAECAVIGVSDTLKGQMPLGFLCLSAGVNRPHDEIAKECVKLVREKIGPVAAFKLACVVDRLPKTRSGKILRGTMVNIADGTPWKMPATIDDPAILDEITEALGKLGYP 5gyz A 2.4 BS02 AMP A 1 G316 A317 P318 Y340 L342 T343 D422 G309 A310 P311 Y333 L335 T336 D415 S198 R218 H245 T343 E344 S195 R211 H238 T336 E337 1.13.12.7 P08659 501 AKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRL 5gz5 A 2.093 BS04 AMP A 1 T185 F186 Y269 K271 Y300 D305 H309 H462 T117 F118 Y201 K203 Y232 D237 H241 H394 3.6.1.- 0003676,0005576,0009143,0016787,0035821,0043262,0046872,0047429,0090729 A0A2D0TC04 1016 YQDICVLPTQSWSCNKLRCGEKRMANVLCSCSEDCLTKKDCCTDYKSICKRETSWLKDQCASQCPEGFDQSPLILFSMDGFRAEYLETWDTLMPNINKLKTCGTHAKYMRAVYPTKTFVNHYTIVTGLYAETHGIIDNNMYDVKLNQNFSLSGSNMRNAAWWGGQPIWHTASYQGLKAATYFWPGSEVKINGSYPTIYKVYNKSTPFEARVMEVLKWLDLPKAKRPDFSTLYIEEPDTTGHKFGPVSGQVIKSLQMADRTLGMLMEGLKQRNLHNCVNLILLADHGMEAISCNRLEYMTDYFNTVDFFMYEGAAPRIRSKNVPKDFYTFDSEAIVKKLTCRKPKQHFKAYLAKDLPKRLHFANNIRIDKVNLMVDRQWLAVRNKKYKYCSGGTHGYDNEFKSMEAIFLAHGPGFKEKTEVTSFENIEVYNLMCDLLKLKPAPNNGTHGSLNHLLKNPFYNPSPAKEQSPPLYCLFGPVPSPDVSGCKCSSITDLEAVNQRLNLIDQAKMQSEADNLPYGRPHVLQHSKYCLLHQTKYISAYSQDILMPLWNSYTISKSLPSASDCLRLDVRIPTVQSQTCSNYQPDLAITPGFLYPPDFSSSGPEQYDALITSNIVPMYKEFARLWNYFHSTLLPKYATERNGLNVISGPIFDYNYDGHFDPYDTIDQYVNNTKIPIPTHYFVVLTSCENSTKTPLNCPPGSLKVLSFILPHRPDNSESCADKSPDNLWVEERMQTHTARVRDVELLTGLDFYSALKQPLSETLRLKTFLPIFINSV 5gzw A 1.489 BS01 AMP A 1 S64 Q120 Y150 N152 Y221 G319 A320 T321 S61 Q117 Y147 N149 Y218 G304 A305 T306 S64 K67 Y112 A114 V121 Y150 G156 E272 K317 A320 S61 K64 Y109 A111 V118 Y147 G153 E269 K302 A305 3.5.2.6 0008800,0017001,0030288 A0A076YIY5 27999057 401 HPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPATKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPPEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVRSNMNPRDINDKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIAAHPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVAAAWQILNALQ 5gzw B 1.489 BS01 AMP B 1 S64 Q120 Y150 N152 Y221 G319 A320 T321 S57 Q113 Y143 N145 Y214 G304 A305 T306 S64 K67 Y112 A114 V121 Y150 G156 E272 K317 A320 S57 K60 Y105 A107 V114 Y143 G149 E265 K302 A305 3.5.2.6 0008800,0017001,0030288 A0A076YIY5 27999057 401 INDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPATKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPPEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVRSNMNPRDINDKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSAAHPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVAAAWQILNALQ 5ie3 A 1.9 BS01 AMP A 1 S171 S289 A290 S291 Y312 A313 M314 T315 D394 L406 R409 K500 S164 S282 A283 S284 Y305 A306 M307 T308 D387 L399 R402 K493 T170 S190 H214 T315 E316 N415 K420 K500 T163 S183 H207 T308 E309 N408 K413 K493 6.2.1.8 0005524,0005737,0005829,0006952,0009506,0009507,0009570,0010030,0010214,0016874,0033611,0048046,0050203,0050832 Q9SMT7 27326693 601 MDSDTLSGLLENVAKKFPDRRALSVSGKFNLTHARLHDLIERAASRLVSDAGIKPGDVVALTFPNTVEFVIMFLAVIRARATAAPLNAAYTAEEFEFYLSDSDSKLLLTSKEGNAPAQEAASKLKISHVTATLLDAGSDLVLSVADATELVNHPDDGALFLHTSGTTSRPKGVPLTQLNLASSVKNIKAVYKLTESDSTVIVLPLFHVHGLLAGLLSSLGAGAAVTLPAAGRFSATTFWPDMKKYNATWYTAVPTIHQIILDRHASHPETEYPKLRFIRSCSASLAPVILSRLEEAFGAPVLEAYAMTEATHLMSSNPLPEEGPHKPGSVGKPVGQEMAILNEKGEIQEPNNKGEVCIRGPNVTKGYKNNPEANKAGFEFGWFHTGDIGYFDTDGYLHLVGRIKELINRGGEKISPIEVDAVLLTHPDVSQGVAFGVPDEKYGEEINCAVIPREGTTVTEEDIKAFCKKNLAAFKVPKRVFITDNLPKTASGKIQRRIVAQHFL 5ie3 B 1.9 BS01 AMP B 1 S289 A290 S291 Y312 A313 M314 T315 D394 L406 R409 K500 S282 A283 S284 Y305 A306 M307 T308 D387 L399 R402 K493 T170 S190 H214 T315 E316 N415 K420 K500 T163 S183 H207 T308 E309 N408 K413 K493 6.2.1.8 0005524,0005737,0005829,0006952,0009506,0009507,0009570,0010030,0010214,0016874,0033611,0048046,0050203,0050832 Q9SMT7 27326693 601 MDSDTLSGLLENVAKKFPDRRALSVSGKFNLTHARLHDLIERAASRLVSDAGIKPGDVVALTFPNTVEFVIMFLAVIRARATAAPLNAAYTAEEFEFYLSDSDSKLLLTSKEGNAPAQEAASKLKISHVTATLLDAGSDLVLSVADATELVNHPDDGALFLHTSGTTSRPKGVPLTQLNLASSVKNIKAVYKLTESDSTVIVLPLFHVHGLLAGLLSSLGAGAAVTLPAAGRFSATTFWPDMKKYNATWYTAVPTIHQIILDRHASHPETEYPKLRFIRSCSASLAPVILSRLEEAFGAPVLEAYAMTEATHLMSSNPLPEEGPHKPGSVGKPVGQEMAILNEKGEIQEPNNKGEVCIRGPNVTKGYKNNPEANKAGFEFGWFHTGDIGYFDTDGYLHLVGRIKELINRGGEKISPIEVDAVLLTHPDVSQGVAFGVPDEKYGEEINCAVIPREGTTVTEEDIKAFCKKNLAAFKVPKRVFITDNLPKTASGKIQRRIVAQHFL 5ikp A 3.4 BS02 AMP A 1 Y75 Y196 R309 Y55 Y176 R283 H377 K568 R569 K574 T676 K680 H344 K535 R536 K541 T643 K647 2.4.1.1 0004645,0005515,0005576,0005737,0005975,0005977,0005980,0008184,0016020,0016757,0030170,0035578,0070062,0102250,0102499 P11216 27402852 902 LGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDDFNVGDYIEAVLDRNLAENISRVLYPNDFEGKELRLKQEYFVVAATLQDIIRRFKSSKFTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNI 5ipp A 1.95 BS01 AMP A 1 R264 R266 G281 G282 G283 H284 A287 S288 G289 R268 R270 G285 G286 G287 H288 A291 S292 G293 3.1.-.-,3.1.3.7 0003676,0004527,0008441 O34600 28894100 401 SMASMKTELIRTISLYDTIILHRHVRPDPDAYGSQCGLTEILRETYPEKNIFAVGTPEPSLSFLYSLDEVDNETYEGALVIVCDTANQERIDDQRYPSGAKLMKIDAHPNEDPYGDLLWVDTSASSVSEMIYELYLEGKEHGWKLNTKAAELIYAGIVGDTGRFLFPNTTEKTLKYAGELIQYPFSSSELFNQLYETKLNVVKLNGFIFQNVSLSENGAASVFIKKDTLEKFGTTASEASQLVGTLGNISGIRAWVFFVEEDDQIRVRFRSKGPVINGLARKYNGGGHPLASGASIYSWDEADRILADLETLCKE 5ipp C 1.95 BS01 AMP C 1 R264 R266 G281 G282 G283 A287 S288 G289 R267 R269 G284 G285 G286 A290 S291 G292 3.1.-.-,3.1.3.7 0003676,0004527,0008441 O34600 28894100 401 MASMKTELIRTISLYDTIILHRHVRPDPDAYGSQCGLTEILRETYPEKNIFAVGTPEPSLSFLYSLDEVDNETYEGALVIVCDTANQERIDDQRYPSGAKLMKIDAHPNEDPYGDLLWVDTSASSVSEMIYELYLEGKEHGWKLNTKAAELIYAGIVGDTGRFLFPNTTEKTLKYAGELIQYPFSSSELFNQLYETKLNVVKLNGFIFQNVSLSENGAASVFIKKDTLEKFGTTASEASQLVGTLGNISGIRAWVFFVEEDDQIRVRFRSKGPVINGLARKYNGGGHPLASGASIYSWDEADRILADLETLCKE 5iso E 2.63 BS01 AMP E 1 T87 T89 D90 V130 I150 H151 R152 T61 T63 D64 V104 I124 H125 R126 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 401 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 5iso E 2.63 BS02 AMP E 2 K170 I240 S242 D245 R269 V276 L277 V297 H298 R299 K144 I214 S216 D219 R243 V250 L251 V271 H272 R273 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 402 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 5iso E 2.63 BS03 AMP E 3 H151 T200 I204 A205 V225 S226 H298 S314 S316 D317 H125 T174 I178 A179 V199 S200 H272 S288 S290 D291 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 403 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 5iso F 2.63 BS01 AMP F 1 T87 T89 D90 V130 I150 H151 R152 T61 T63 D64 V104 I124 H125 R126 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 401 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 5iso F 2.63 BS02 AMP F 2 K170 I240 S242 D245 R269 V276 L277 V297 H298 R299 K144 I214 S216 D219 R243 V250 L251 V271 H272 R273 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 402 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 5iso F 2.63 BS03 AMP F 3 H151 T200 I204 A205 V225 S226 H298 S314 S316 D317 H125 T174 I178 A179 V199 S200 H272 S288 S290 D291 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 403 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 5jda A 1.401 BS01 AMP A 1 R45 V125 Y142 E169 W245 R46 V126 Y143 E170 W246 2.7.11.1 0000166,0046872 Q739M5 27185916 401 SMLPSYDFFIHPMNLVELKKDIWSDSPVPAKLTYGKKKYDIDIVYRGAHIREFEKKSYHVMFYKPKKFQGAKEFHLNSEFMDPSLIRNKLSLDFFHDIGVLSPKSQHVFIKINGQIQGVYLQLESVDENFLKNRGLPSGSIYYAIDDDANFSLMSERDKDVKTELFAGYEFKYSNENSEEQLSEFVFQANALSREAYEKEIGKFLHVDKYLRWLAGVIFTQNFDGFVHNYALYHNDETNLFEVIPWDYDATWGRDVQGRPLNHEYIRIQGYNTLSARLLDIPIFRKQYRSILEEILAEQFTVSFMMPKVESLCESIRPYLLQDPYMKEKLETFDQEADMIEEYINKRRKYIQDHLHELD 5jju B 2.312 BS03 AMP B 1 R112 S292 R294 G309 G310 A316 G317 R95 S275 R277 G292 G293 A299 G300 ? 0000166,0003676,0046872 A5U6I9 27371563 1003 GARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLDGCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALGDLTDSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLATDTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVGGRGLVYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNLAAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALGLTRAPP 5jju B 2.312 BS04 AMP B 2 D106 H131 H132 D181 W187 H312 D89 H114 H115 D164 W170 H295 ? 0000166,0003676,0046872 A5U6I9 27371563 1004 GARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLDGCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALGDLTDSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLATDTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVGGRGLVYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNLAAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALGLTRAPP 5jmv A 3.38647 BS01 AMP A 1 K12 S129 G130 G155 L158 D159 G172 P173 G252 V253 A255 N256 K15 S127 G128 G153 L156 D157 G170 P171 G250 V251 A253 N254 2.3.1.234,2.7.11.1 0000408,0002949 Q58530 27302132 401 MDPMICLGLEGTAEKTGVGIVTSDGEVLFNKTIMYKPNPREAADHHAETFPKLIKEAFEVVDKNEIDLIAFSQGPGLGPSLRVTATVARTLSLTLKKPIIGVNHCIAHIEIGKLTTEAEDPLTLYVSGGNTQVIAYVSKKYRVFGETLDIAVGNCLDQFARYVNLPHPGGPYIEELARKGKKLVDLPYTVKGMDIAFSGLLTAAMRAYDAGERLEDICYSLQEYAFSMLTEITERALAHTNKGEVMLVGGVAANNRLREMLKAMCEGQNVDFYVPPKEFCGDNGAMIAWLGLLMHKNGRWMSLDETKIIPNYRTDMVEVNWIK 5jmv B 3.38647 BS01 AMP B 1 K12 S129 G130 G155 D159 G172 P173 G252 V253 D284 K15 S125 G126 G151 D155 G168 P169 G248 V249 D280 2.3.1.234,2.7.11.1 0000408,0002949 Q58530 27302132 401 MDPMICLGLEGTAEKTGVGIVTSDGEVLFNKTIMINPREAADHHAETFPKLIKEAFEVVDKNEIDLIAFSQGPGLGPSLRVTATVARTLSLTLKKPIIGVNHCIAHIEIGKLTTEAEDPLTLYVSGGNTQVIAYVSKKYRVFGETLDIAVGNCLDQFARYVNLPHPGGPYIEELARKGKKLVDLPYTVKGMDIAFSGLLTAAMRAYDAGERLEDICYSLQEYAFSMLTEITERALAHTNKGEVMLVGGVAANNRLREMLKAMCEGQNVDFYVPPKEFCGDNGAMIAWLGLLMHKNGRWMSLDETKIIPNYRTDMVEVNWIK 5jmv C 3.38647 BS01 AMP C 1 K12 S129 G130 G155 D159 G172 P173 E176 G252 V253 N256 G283 D284 K13 S123 G124 G149 D153 G166 P167 E170 G246 V247 N250 G277 D278 2.3.1.234,2.7.11.1 0000408,0002949 Q58530 27302132 401 PMICLGLEGTAEKTGVGIVTSDGEVLFNKTIMYNPREAADHHAETFPKLIKEAFEVVDKNEIDLIAFSQGPGLGPSLRVTATVARTLSLTLKKPIIGVNHCIAHIEIGKLTTEAEDPLTLYVSGGNTQVIAYVSKKYRVFGETLDIAVGNCLDQFARYVNLPHPGGPYIEELARKGKKLVDLPYTVKGMDIAFSGLLTAAMRAYDAGERLEDICYSLQEYAFSMLTEITERALAHTNKGEVMLVGGVAANNRLREMLKAMCEGQNVDFYVPPKEFCGDNGAMIAWLGLLMHKNGRWMSLDETKIIPNYRTDMVEVNWI 5k27 A 2.58 BS01 AMP A 1 H336 F422 V423 L432 G433 I436 H338 F424 V425 L434 G435 I438 0000287,0005737,0005975,0006000,0006096,0008443,0016773 29273585 501 GHMEDIKKISIFLAYNVNVDAIKYLKEEDIQKLIEEFGEEEIIEKIEEYPRKIKEPLDFVARLIHAIKTGKPAEVPLDNEELNKWFDSLFKYDEERMGGQVGIIANLLAILDLKKVIAYSPLLSKKQAEMFNNDLLYPIVENGKLVLKKPIEAYKDNDPIKINRIFEFKEGIKFKLGDEKIIAPQANRFIVASRPENLARIEIKEDLKKYLPEIGEMVDCAILSGYQGIKEKYSDGKTAEYYFKRAKEDIKLLKKKDIKVHLEFASIQNIKIRKKVVDYILPNVDSVGMDETEIANILNILGYEELSEKILKDSKIEDVIEGAKILLDKFNLEVVQVHTIYYILFISKKDNPLSKEELKKTLEFATILAATKAKLGDIKNIEDLKVGLKVPHNKYGELLKEIVEKLKKKKKKEDYKIVLIPSRFVENPKSTVGLGDTISTGAFVSYVSLLKKK 5k27 B 2.58 BS01 AMP B 1 T337 I338 F422 V423 G431 L432 G433 I436 T335 I336 F420 V421 G429 L430 G431 I434 0000287,0005737,0005975,0006000,0006096,0008443,0016773 29273585 501 MEDIKKISIFLAYNVNVDAIKYLKEEDIQKLIEEFGEEEIIEKIEEYPRKIKEPLDFVARLIHAIKTGKPAEVPLDNEELNKWFDSLFKYDEERMGGQVGIIANLLAILDLKKVIAYSPLLSKKQAEMFNNDLLYPIVENGKLVLKKPIEAYKDNDPIKINRIFEFKEGIKFKLGDEKIIAPQANRFIVASRPLARIEIKEDLKKYLPEIGEMVDCAILSGYQGIKEKYSDGKTAEYYFKRAKEDIKLLKKKDIKVHLEFASIQNIKIRKKVVDYILPNVDSVGMDETEIANILNILGYEELSEKILKDSKIEDVIEGAKILLDKFNLEVVQVHTIYYILFISKKDNPLSKEELKKTLEFATILAATKAKLGDIKNIEDLKVGLKVPHNKYGELLKEIVEKLKKKKKKEDYKIVLIPSRFVENPKSTVGLGDTISTGAFVSYVSLLKKK 5kkg A 2.608 BS01 AMP A 1 D288 H336 T337 F422 V423 L432 G433 I436 D289 H337 T338 F420 V421 L430 G431 I434 0000287,0005737,0005975,0006000,0006096,0008443,0016773 29273585 501 HMEDIKKISIFLAYNVNVDAIKYLKEEDIQKLIEEFGEEEIIEKIEEYPRKIKEPLDFVARLIHAIKTGKPAAVPLDNEELNKWFDSLFKYDEERMGGQVGIIANLLAILDLKKVIAYSPLLSKKQAEMFNNDLLYPIVENGKLVLKKPIEAYKDNDPIKINRIFEFKEGIKFKLGDEKIIAPQANRFIVASRPENLARIEIKEDLKKYLPEIGEMVDCAILSGYQGIKEKYSDGKTAEYYFKRAKEDIKLLKKKDIKVHLEFASIQNIKIRKKVVDYILPNVDSVGMDETEIANILNILGYEELSEKILKDSKIEDVIEGAKILLDKFNLEVVQVHTIYYILFISKKDNPLSKEELKKTLEFATILAATKAKLGDIKNIEDLKVGLKVPHNKYGELLKEIVEKLKKKEDYKIVLIPSRFVENPKSTVGLGDTISTGAFVSYVSLLKKK 5klz B 1.5 BS01 AMP B 1 D43 I44 N99 G105 S107 V108 H112 H114 D32 I33 N88 G94 S96 V97 H101 H103 3.4.22.-,3.9.1.- 0000118,0000166,0003824,0005080,0005515,0005634,0005654,0005737,0005829,0005856,0005886,0006355,0006508,0006915,0007165,0008234,0009154,0016787,0016926,0016929,0043530,0050850,0070062,0072332 -logKd/Ki=6.37, Kd=0.423uM P49773 28968488 201 RPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 5kod A 2.202 BS01 AMP A 1 S110 I312 T314 A339 S340 S341 Y360 D427 F443 R446 S93 I295 T297 A322 S323 S324 Y343 D392 F408 R411 6.3.2.- 0009733,0010120,0010252,0010279,0016874,1901183 O81829 27849615 701 DQKNKQKLQLIEELTSNADQVQRQVLEEILTRNADVEYLRRHDLNGRTDRETFKNIMPVITYEDIEPEINRIANGDKSPILSSKPISEFLTSSGTSGGERKLMPTIEEELDRRSLLYSLLMPVMSQFVPGLENGKGMYFLFIKSESKTPGGLPARPVLTSYYKSSHFKERPYDPYTNYTSPNETILCSDSYQSMYSQMLCGLCQHQEVLRVGAVFASGFIRAIKFLEKHWIELVRDIRTGTLSSLITDPSVREAVAKILKPSPKLADFVEFECKKSSWQGIITRLWPNTKYVDVIVTGTMSQYIPTLDYYSNGLPLVCTMYASSECYFGVNLRPLCKPSEVSYTLIPSMAYFEFLPVHRQQELVDLVDVKLGQEYELVVTTYAGLCRYRVGDLLRVTGFKNKAPQFSFICRKNVVLSIDSDKTDEVELQNAVKNAVTHLVPFDASLSEYTSYADTSSIPGHYVLFWELCLDGNTPIPPSVFEDCCLAVEESFNTVYRQGRVSDKSIGPLEIKIVEPGTFDKLMDYAISLGASINQYKTPRCVKFAPIIELLNSRVVDSYFSPKCPKWVPGHKQ 5kod B 2.202 BS01 AMP B 1 S109 S110 I312 T314 A339 S340 S341 Y360 D427 F443 R446 S94 S95 I297 T299 A324 S325 S326 Y345 D398 F414 R417 6.3.2.- 0009733,0010120,0010252,0010279,0016874,1901183 O81829 27849615 701 TLDQKNKQKLQLIEELTSNADQVQRQVLEEILTRNADVEYLRRHDLNGRTDRETFKNIMPVITYEDIEPEINRIANGDKSPILSSKPISEFLTSSGTSGGERKLMPTIEEELDRRSLLYSLLMPVMSQFVPGLENGKGMYFLFIKSESKTPGGLPARPVLTSYYKSSHFKERPYDPYTNYTSPNETILCSDSYQSMYSQMLCGLCQHQEVLRVGAVFASGFIRAIKFLEKHWIELVRDIRTGTLSSLITDPSVREAVAKILKPSPKLADFVEFECKKSSWQGIITRLWPNTKYVDVIVTGTMSQYIPTLDYYSNGLPLVCTMYASSECYFGVNLRPLCKPSEVSYTLIPSMAYFEFLPVHLTEKEQQELVDLVDVKLGQEYELVVTTYAGLCRYRVGDLLRVTGFKNKAPQFSFICRKNVVLSIDSDKTDEVELQNAVKNAVTHLVPFDASLSEYTSYADTSSIPGHYVLFWELCLDGNTPIPPSVFEDCCLAVEESFNTVYRQGRVSDKSIGPLEIKIVEPGTFDKLMDYAISLGANQYKTPRCVKFAPIIELLNSRVVDSYFSPKCPKWVP 5kod C 2.202 BS01 AMP C 1 S109 S110 I312 T314 M337 Y338 A339 S340 S341 Y360 D427 F443 R446 S94 S95 I293 T295 M318 Y319 A320 S321 S322 Y341 D397 F413 R416 6.3.2.- 0009733,0010120,0010252,0010279,0016874,1901183 O81829 27849615 701 TLDQKNKQKLQLIEELTSNADQVQRQVLEEILTRNADVEYLRRHDLNGRTDRETFKNIMPVITYEDIEPEINRIANGDKSPILSSKPISEFLTSSGTSGGERKLMPTIEEELDRRSLLYSLLMPVMSQFVPGLENGKGMYFLFIKSESKTPGGLPARPVLTSYYKSSHFKDPYTNYTSPNETILCSDSYQSMYSQMLCGLCQHQEVLRVGAVFASGFIRAIKFLEKHWIELVRDIRTGTLSSLITDPSVREAVAKILKPSPKLADFVEFECKKSSWQGIITRLWPNTKYVDVIVTGTMSQYIPTLDYYSNGLPLVCTMYASSECYFGVNLRPLCKPSEVSYTLIPSMAYFEFLPVHRNALTEKEQQELVDLVDVKLGQEYELVVTTYAGLCRYRVGDLLRVTGFKNKAPQFSFICRKNVVLSIDSDKTDEVELQNAVKNAVTHLVPFDASLSEYTSYADTSSIPGHYVLFWELCLDPPSVFEDCCLAVEESFNTVYRQGRVSDKSIGPLEIKIVEPGTFDKLMDYAISLGASINQYKTPRCVKFAPIIELLNSRVVDSYFSPKCPK 5kod D 2.202 BS01 AMP D 1 S110 I312 T314 Y338 A339 S340 S341 Y360 D427 F443 R446 S95 I297 T299 Y323 A324 S325 S326 Y345 D392 F408 R411 6.3.2.- 0009733,0010120,0010252,0010279,0016874,1901183 O81829 27849615 701 TLDQKNKQKLQLIEELTSNADQVQRQVLEEILTRNADVEYLRRHDLNGRTDRETFKNIMPVITYEDIEPEINRIANGDKSPILSSKPISEFLTSSGTSGGERKLMPTIEEELDRRSLLYSLLMPVMSQFVPGLENGKGMYFLFIKSESKTPGGLPARPVLTSYYKSSHFKERPYDPYTNYTSPNETILCSDSYQSMYSQMLCGLCQHQEVLRVGAVFASGFIRAIKFLEKHWIELVRDIRTGTLSSLITDPSVREAVAKILKPSPKLADFVEFECKKSSWQGIITRLWPNTKYVDVIVTGTMSQYIPTLDYYSNGLPLVCTMYASSECYFGVNLRPLCKPSEVSYTLIPSMAYFEFLPVHQELVDLVDVKLGQEYELVVTTYAGLCRYRVGDLLRVTGFKNKAPQFSFICRKNVVLSIDSDKTDEVELQNAVKNAVTHLVPFDASLSEYTSYADTSSIPGHYVLFWELCPIPPSVFEDCCLAVEESFNTVYRQGRVSDKSIGPLEIKIVEPGTFDKLMDYAISLGASINQYKTPRCVKFAPIIELLNSRVVDSYFSPKCPKWVPGH 5kq5 C 3.41 BS01 AMP C 1 H150 T199 I203 A204 V224 S225 I311 S313 S315 D316 H123 T165 I169 A170 V190 S191 I270 S272 S274 D275 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 27490827 401 YTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 5kq5 C 3.41 BS02 AMP C 2 R69 I239 S241 D244 R268 L276 V296 H297 R298 R42 I205 S207 D210 R234 L235 V255 H256 R257 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 27490827 402 YTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 5l3q A 3.2 BS02 AMP A 1 E277 H278 E246 H247 3.6.5.4 0003924,0005525,0006614,0008312,0016887,0048500 P61011 27241309 505 NEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLG 5l3q B 3.2 BS02 AMP A 1 F457 L531 F126 L200 ? 0003723,0003924,0005047,0005525,0005783,0005785,0005789,0006613,0006614,0006617,0006886,0016020,0016887,0045047,0070062 P08240 27241309 505 SLSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYVVTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEKHGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA 5l3q D 3.2 BS02 AMP C 1 F457 L531 F126 L200 ? 0003723,0003924,0005047,0005525,0005783,0005785,0005789,0006613,0006614,0006617,0006886,0016020,0016887,0045047,0070062 P08240 27241309 506 SLSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYVVTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEKHGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA 5l6v A 2.667 BS03 AMP A 1 K39 R40 H46 R52 E370 R386 A387 K31 R32 H38 R44 E362 R378 A379 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 HLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQE 5l6v B 2.667 BS01 AMP B 1 K39 R40 H46 R52 T79 E370 R386 A387 R419 K31 R32 H38 R44 T71 E362 R378 A379 R411 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 HLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQ 5l6v C 2.667 BS01 AMP C 1 K39 R40 H46 R52 T79 E370 R386 A387 R419 K30 R31 H37 R43 T70 E361 R377 A378 R410 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 LMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQE 5l6v D 2.667 BS01 AMP D 1 K39 R40 H46 R52 T79 E370 R386 A387 K31 R32 H38 R44 T71 E353 R369 A370 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 HLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQE 5l6v E 2.667 BS02 AMP E 1 R40 H46 R52 T79 E370 R386 A387 R31 H37 R43 T70 E350 R366 A367 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 LMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 5l6v F 2.667 BS01 AMP F 1 R40 H46 R52 T79 E370 R386 A387 R419 R31 H37 R43 T70 E350 R366 A367 R399 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 LMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 5l6v G 2.667 BS02 AMP G 1 K39 R40 H46 R52 T79 E370 R386 A387 K31 R32 H38 R44 T71 E351 R367 A368 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 HLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQE 5l6v H 2.667 BS02 AMP H 1 K39 R40 H46 R52 T79 E370 R386 A387 K30 R31 H37 R43 T70 E357 R373 A374 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 LMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRNWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQ 5l6v I 2.667 BS02 AMP I 1 R40 H46 R52 T79 E370 R386 A387 R32 H38 R44 T71 E340 R356 A357 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 HLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDEDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDFGKDLIPKITAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQE 5l6v J 2.667 BS03 AMP J 1 R40 H46 R52 T79 E370 R386 A387 R419 R32 H38 R44 T71 E352 R368 A369 R401 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 HLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPARGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQE 5l6v K 2.667 BS03 AMP K 1 R40 H46 R52 T79 E370 R386 A387 R31 H37 R43 T70 E361 R377 A378 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 LMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQE 5l6v L 2.667 BS01 AMP L 1 R40 H46 R52 T79 E370 R386 A387 R419 R31 H37 R43 T70 E351 R367 A368 R400 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 LMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 5l6v M 2.667 BS01 AMP M 1 K39 R40 H46 R52 T79 R386 A387 R419 K30 R31 H37 R43 T70 R370 A371 R403 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 LMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 5l6v N 2.667 BS02 AMP N 1 K39 R40 H46 R52 T79 E370 R386 A387 R419 K31 R32 H38 R44 T71 E362 R378 A379 R411 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 HLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQE 5l6v O 2.667 BS01 AMP O 1 K39 R40 H46 R52 T79 E370 R386 A387 K31 R32 H38 R44 T71 E355 R371 A372 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 HLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQE 5l6v P 2.667 BS01 AMP P 1 K39 R40 H46 R52 T79 E370 R386 A387 K32 R33 H39 R45 T72 E363 R379 A380 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 27545622 501 DHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQE 5l95 A 2.1 BS01 AMP A 1 G80 G82 G83 D104 Y105 K127 D183 N184 G13 G15 G16 D37 Y38 K54 D110 N111 ? 0008641 Q9GZZ9 27653677 401 YEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELFFQPHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLSCVDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVVAANIDEKTSLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMSMKPNPQCDDRNCRKQQEEYKKKVAALPEIIHEDNEWGIELV 5lcd A 2.66 BS01 AMP A 1 G92 V93 P94 R106 E126 D127 V130 G92 V93 P94 R106 E126 D127 V130 0006797,0008976,0016776 29531036 301 MKKYRVQPDGRFELKRFDPDDTSAFEGGKQAALEALAVLNRRLEKLQELLYAEGQHKVLVVLQAMDAGGKDGTIRVVFDGVNPSGVRVASFGVPTEQELARDYLWRVHQQVPRKGELVIFNRSHYEDVLVVRVKNLVPQQVWQKRYRHIREFERMLADEGTTILKFFLHISKDEQRQRLQERLDNPEKRWKFRMGDLEDRRLWDRYQEAYEAAIRETSTEYAPWYVIPANKNWYRNWLVSHILVETLEGLAMQYPQ 5lcd B 2.66 BS01 AMP B 1 G92 V93 P94 R106 E126 D127 V130 G92 V93 P94 R106 E126 D127 V130 0006797,0008976,0016776 29531036 301 MKKYRVQPDGRFELKRFDPDDTSAFEGGKQAALEALAVLNRRLEKLQELLYAEGQHKVLVVLQAMDAGGKDGTIRVVFDGVNPSGVRVASFGVPTEQELARDYLWRVHQQVPRKGELVIFNRSHYEDVLVVRVKNLVPQQVWQKRYRHIREFERMLADEGTTILKFFLHISKDEQRQRLQERLDNPEKRWKFRMGDLEDRRLWDRYQEAYEAAIRETSTEYAPWYVIPANKNWYRNWLVSHILVETLEGLAMQYPQPE 5lcd C 2.66 BS01 AMP C 1 F91 G92 V93 P94 R106 E126 D127 V130 R193 F91 G92 V93 P94 R106 E126 D127 V130 R193 0006797,0008976,0016776 29531036 301 MKKYRVQPDGRFELKRFDPDDTSAFEGGKQAALEALAVLNRRLEKLQELLYAEGQHKVLVVLQAMDAGGKDGTIRVVFDGVNPSGVRVASFGVPTEQELARDYLWRVHQQVPRKGELVIFNRSHYEDVLVVRVKNLVPQQVWQKRYRHIREFERMLADEGTTILKFFLHISKDEQRQRLQERLDNPEKRWKFRMGDLEDRRLWDRYQEAYEAAIRETSTEYAPWYVIPANKNWYRNWLVSHILVETLEGLAMQYPQ 5lcd D 2.66 BS01 AMP D 1 G92 V93 P94 R106 R122 E126 D127 V130 G92 V93 P94 R106 R122 E126 D127 V130 0006797,0008976,0016776 29531036 301 MKKYRVQPDGRFELKRFDPDDTSAFEGGKQAALEALAVLNRRLEKLQELLYAEGQHKVLVVLQAMDAGGKDGTIRVVFDGVNPSGVRVASFGVPTEQELARDYLWRVHQQVPRKGELVIFNRSHYEDVLVVRVKNLVPQQVWQKRYRHIREFERMLADEGTTILKFFLHISKDEQRQRLQERLDNPEKRWKFRMGDLEDRRLWDRYQEAYEAAIRETSTEYAPWYVIPANKNWYRNWLVSHILVETLEGLAMQYPQPE 5m45 B 1.87 BS01 AMP B 1 T21 M22 G311 G312 A352 F405 L406 G473 D692 A693 T694 T695 T13 M14 G303 G304 A344 F397 L398 G465 D684 A685 T686 T687 6.4.1.6 0005524,0005829,0006749,0016787,0016874,0017168,0018710,0140977 Q8RM04 28775283 801 RNVQVLGIDAGGTMTDTFFVDQDGDFVVGKAQSTPQNEALGLIASSEDGLANWGMSLHEALAQLQTGVYSGTAMLNRVVQRKGLKCGLIVNRGMEDFHRMGRAVQSHLGYAYEDRIHLNTHRYDPPLVPRHLTRGVVERTDMMGTQVIPLREDTARDAARDLIAADAEGIVISLLHSYKNPVNERRVRDIVLEEVEKSGKKIPVFASADYYPVRKETHRTNTTILEGYAAEPSRQTLSKISNAFKERGTKFDFRVMATHGGTISWKAKELARTIVSGPIGGVIGAKYLGEVLGYKNIACSDIGGTSFDVALITQGEMTIKNDPDMARLVLSLPLVAMDSVGAGAGSFIRLDPYTRAIKLGPDSAGYRVGVCWKESGIETVTISDCHMVLGYLNPDNFLGGAVKLDRQRSVDAIKAQIADPLGLSVEDAAAGVIELLDSDLRDYLRSMISGKGYSPASFVCFSYGGAGPVHTYGYTEGLGFEDVIVPAWAAGFSAFGCAAADFEYRYDKSLDINMPTETPDTDKEKAAATLQAAWEELTKNVLEEFKLNGYSADQVTLQPGYRMQYRGQLNDLEIESPLAQAHTAADWDQLTDAFNATYGRVYAASARSPELGYSVTGAIMRGMVPIPKPKIPKEPEEGETPPESAKIGTRKFYRKKRWVDAQLYHMESLRPGNRVMGPAVIESDATTFVVPDGFETWLDGHRLFHLREV 5m45 E 1.87 BS01 AMP E 1 G20 T21 M22 G311 G312 A352 F405 L406 G473 A474 D692 A693 T694 T695 G12 T13 M14 G303 G304 A344 F397 L398 G465 A466 D684 A685 T686 T687 6.4.1.6 0005524,0005829,0006749,0016787,0016874,0017168,0018710,0140977 Q8RM04 28775283 801 RNVQVLGIDAGGTMTDTFFVDQDGDFVVGKAQSTPQNEALGLIASSEDGLANWGMSLHEALAQLQTGVYSGTAMLNRVVQRKGLKCGLIVNRGMEDFHRMGRAVQSHLGYAYEDRIHLNTHRYDPPLVPRHLTRGVVERTDMMGTQVIPLREDTARDAARDLIAADAEGIVISLLHSYKNPVNERRVRDIVLEEVEKSGKKIPVFASADYYPVRKETHRTNTTILEGYAAEPSRQTLSKISNAFKERGTKFDFRVMATHGGTISWKAKELARTIVSGPIGGVIGAKYLGEVLGYKNIACSDIGGTSFDVALITQGEMTIKNDPDMARLVLSLPLVAMDSVGAGAGSFIRLDPYTRAIKLGPDSAGYRVGVCWKESGIETVTISDCHMVLGYLNPDNFLGGAVKLDRQRSVDAIKAQIADPLGLSVEDAAAGVIELLDSDLRDYLRSMISGKGYSPASFVCFSYGGAGPVHTYGYTEGLGFEDVIVPAWAAGFSAFGCAAADFEYRYDKSLDINMPTETPDTDKEKAAATLQAAWEELTKNVLEEFKLNGYSADQVTLQPGYRMQYRGQLNDLEIESPLAQAHTAADWDQLTDAFNATYGRVYAASARSPELGYSVTGAIMRGMVPIPKPKIPKEPEEGETPPESAKIGTRKFYRKKRWVDAQLYHMESLRPGNRVMGPAVIESDATTFVVPDGFETWLDGHRLFHLREV 5m45 H 1.87 BS01 AMP H 1 G20 T21 M22 G311 G312 A352 F405 L406 G473 T694 T695 G12 T13 M14 G303 G304 A344 F397 L398 G465 T686 T687 6.4.1.6 0005524,0005829,0006749,0016787,0016874,0017168,0018710,0140977 Q8RM04 28775283 801 RNVQVLGIDAGGTMTDTFFVDQDGDFVVGKAQSTPQNEALGLIASSEDGLANWGMSLHEALAQLQTGVYSGTAMLNRVVQRKGLKCGLIVNRGMEDFHRMGRAVQSHLGYAYEDRIHLNTHRYDPPLVPRHLTRGVVERTDMMGTQVIPLREDTARDAARDLIAADAEGIVISLLHSYKNPVNERRVRDIVLEEVEKSGKKIPVFASADYYPVRKETHRTNTTILEGYAAEPSRQTLSKISNAFKERGTKFDFRVMATHGGTISWKAKELARTIVSGPIGGVIGAKYLGEVLGYKNIACSDIGGTSFDVALITQGEMTIKNDPDMARLVLSLPLVAMDSVGAGAGSFIRLDPYTRAIKLGPDSAGYRVGVCWKESGIETVTISDCHMVLGYLNPDNFLGGAVKLDRQRSVDAIKAQIADPLGLSVEDAAAGVIELLDSDLRDYLRSMISGKGYSPASFVCFSYGGAGPVHTYGYTEGLGFEDVIVPAWAAGFSAFGCAAADFEYRYDKSLDINMPTETPDTDKEKAAATLQAAWEELTKNVLEEFKLNGYSADQVTLQPGYRMQYRGQLNDLEIESPLAQAHTAADWDQLTDAFNATYGRVYAASARSPELGYSVTGAIMRGMVPIPKPKIPKEPEEGETPPESAKIGTRKFYRKKRWVDAQLYHMESLRPGNRVMGPAVIESDATTFVVPDGFETWLDGHRLFHLREV 5m45 K 1.87 BS01 AMP K 1 T21 M22 G311 G312 A352 F405 L406 G473 A693 T694 T695 T13 M14 G303 G304 A344 F397 L398 G465 A685 T686 T687 6.4.1.6 0005524,0005829,0006749,0016787,0016874,0017168,0018710,0140977 Q8RM04 28775283 801 RNVQVLGIDAGGTMTDTFFVDQDGDFVVGKAQSTPQNEALGLIASSEDGLANWGMSLHEALAQLQTGVYSGTAMLNRVVQRKGLKCGLIVNRGMEDFHRMGRAVQSHLGYAYEDRIHLNTHRYDPPLVPRHLTRGVVERTDMMGTQVIPLREDTARDAARDLIAADAEGIVISLLHSYKNPVNERRVRDIVLEEVEKSGKKIPVFASADYYPVRKETHRTNTTILEGYAAEPSRQTLSKISNAFKERGTKFDFRVMATHGGTISWKAKELARTIVSGPIGGVIGAKYLGEVLGYKNIACSDIGGTSFDVALITQGEMTIKNDPDMARLVLSLPLVAMDSVGAGAGSFIRLDPYTRAIKLGPDSAGYRVGVCWKESGIETVTISDCHMVLGYLNPDNFLGGAVKLDRQRSVDAIKAQIADPLGLSVEDAAAGVIELLDSDLRDYLRSMISGKGYSPASFVCFSYGGAGPVHTYGYTEGLGFEDVIVPAWAAGFSAFGCAAADFEYRYDKSLDINMPTETPDTDKEKAAATLQAAWEELTKNVLEEFKLNGYSADQVTLQPGYRMQYRGQLNDLEIESPLAQAHTAADWDQLTDAFNATYGRVYAASARSPELGYSVTGAIMRGMVPIPKPKIPKEPEEGETPPESAKIGTRKFYRKKRWVDAQLYHMESLRPGNRVMGPAVIESDATTFVVPDGFETWLDGHRLFHLREV 5mko A 2.65 BS01 AMP A 1 A53 V54 S55 S60 I79 K135 T153 G154 H155 A54 V55 S56 S61 I80 K136 T154 G155 H156 2.8.1.- 0000049,0002098,0002143,0002144,0005524,0008033,0016740,0034227,0046872,0051539 O58038 28655838 401 SMKCKFCSREAYIKIHYPKMYLCEEHFKEYFERKVSRTIERYKLLTKDERILVAVSGGKDSAVTAYVLKKLGYNIECLHINLGISGYSEKSEEYAKKQCKLIGAPLHIVRIKEILGYGIGEVKTRRPPCSYCGLTKRYIMNKFAYDNGFDAIATGHNLDDEASFLLNNILHWNTEYLAKGGPILPQQGKFIKKVKPLYEVTEREVVAYALAVGLEYIVEECPYARGATTLDMKGVLNELEEKRPGTKFNFVRGYLKKKKLFEPEIKEKEIKECKICRMPSSGDICAFCKFWGLKKEINFKVSSTDEEP 5mko B 2.65 BS01 AMP B 1 A53 V54 S55 S60 I79 K135 T153 G154 H155 A54 V55 S56 S61 I80 K136 T154 G155 H156 2.8.1.- 0000049,0002098,0002143,0002144,0005524,0008033,0016740,0034227,0046872,0051539 O58038 28655838 401 SMKCKFCSREAYIKIHYPKMYLCEEHFKEYFERKVSRTIERYKLLTKDERILVAVSGGKDSAVTAYVLKKLGYNIECLHINLGISGYSEKSEEYAKKQCKLIGAPLHIVRIKEILGYGIGEVKTRRPPCSYCGLTKRYIMNKFAYDNGFDAIATGHNLDDEASFLLNNILHWNTEYLAKGGPILPQQGKFIKKVKPLYEVTEREVVAYALAVGLEYIVEECPYGATTLDMKGVLNELEEKRPGTKFNFVRGYLKKKKLFEPEIKEKEIKECKICRMPSSGDICAFCKFWGLKKEINFKVSST 5msc A 1.85 BS01 AMP A 1 H300 S395 A396 P397 D416 G417 Y418 G419 S420 T421 D495 Y507 R510 H296 S391 A392 P393 D412 G413 Y414 G415 S416 T417 D491 Y503 R506 M275 H300 T421 L517 K616 M271 H296 T417 L513 K612 1.2.1.-,1.2.1.30 0001676,0004467,0005524,0006629,0016020,0016491,0016620,0031177,0047683,0050661 Q6RKB1 28719588 1201 SPDERLQRRIAQLFAEDEQVKAARPLEAVSAAVSAPGMRLAQIAATVMAGYADRPAAGQRAFELNTDDATGRTSLRLLPRFETITYRELWQRVGEVAAAWHHDPENPLRAGDFVALLGFTSIDYATLDLADIHLGAVTVPLQASAAVSQLIAILTETSPRLLASTPEHLDAAVECLLAGTTPERLVVFDYHPEDDDQRAAFESARRRLADAGSLVIVETLDAVRARGRDLPAAPLFVPDTDDDPLALLIYTSGSTGTPKGAMYTNRLAATMWQGNSMLQGNSQRVGINLNYMPMSHIAGRISLFGVLARGGTAYFAAKSDMSTLFEDIGLVRPTEIFFVPRVCDMVFQRYQSELDRRSVAGADLDTLDREVKADLRQNYLGGRFLVAVVGSAPLAAEMKTFMESVLDLPLHDGYGSTEAGASVLLDNQIQRPPVLDYKLVDVPELGYFRTDRPHPRGELLLKAETTIPGYYKRPEVTAEIFDEDGFYKTGDIVAELEHDRLVYVDRRNNVLKLSQGEFVTVAHLEAVFASSPLIRQIFIYGSSERSYLLAVIVPTDDALRGRDTATLKSALAESIQRIAKDANLQPYEIPRDFLIETEPFTIANGLLSGIAKLLRPNLKERYGAQLEQMYTDLAT 5msd A 1.71 BS01 AMP A 1 H300 S395 A396 P397 G417 Y418 T421 D495 Y507 R510 K616 H297 S392 A393 P394 G414 Y415 T418 D492 Y504 R507 K613 M275 H300 T421 L517 K616 M272 H297 T418 L514 K613 1.2.1.-,1.2.1.30 0001676,0004467,0005524,0006629,0016020,0016491,0016620,0031177,0047683,0050661 Q6RKB1 28719588 1201 DSPDERLQRRIAQLFAEDEQVKAARPLEAVSAAVSAPGMRLAQIAATVMAGYADRPAAGQRAFELNTDDATGRTSLRLLPRFETITYRELWQRVGEVAAAWHHDPENPLRAGDFVALLGFTSIDYATLDLADIHLGAVTVPLQASAAVSQLIAILTETSPRLLASTPEHLDAAVECLLAGTTPERLVVFDYHPEDDDQRAAFESARRRLADAGSLVIVETLDAVRARGRDLPAAPLFVPDTDDDPLALLIYTSGSTGTPKGAMYTNRLAATMWQGNSMLQGNSQRVGINLNYMPMSHIAGRISLFGVLARGGTAYFAAKSDMSTLFEDIGLVRPTEIFFVPRVCDMVFQRYQSELDRRSVAGADLDTLDREVKADLRQNYLGGRFLVAVVGSAPLAAEMKTFMESVLDLPLHDGYGSTEAGASVLLDNQIQRPPVLDYKLVDVPELGYFRTDRPHPRGELLLKAETTIPGYYKRPEVTAEIFDEDGFYKTGDIVAELEHDRLVYVDRRNNVLKLSQGEFVTVAHLEAVFASSPLIRQIFIYGSSERSYLLAVIVPTDDALRGRDTATLKSALAESIQRIAKDANLQPYEIPRDFLIETEPFTIANGLLSGIAKLLRPNLKERYGAQLEQMYTDLAT 5msq A 1.74 BS01 AMP A 1 H300 S395 A396 P397 D416 G417 Y418 S420 T421 D495 Y507 R510 K616 H292 S387 A388 P389 D408 G409 Y410 S412 T413 D487 Y499 R502 K608 M275 H300 T421 L517 K616 M267 H292 T413 L509 K608 1.2.1.-,1.2.1.30 0001676,0004467,0005524,0006629,0016020,0016491,0016620,0031177,0047683,0050661 Q6RKB1 1201 RLQRRIAQLFAEDEQVKAARPLEAVSAAVSAPGMRLAQIAATVMAGYADRPAAGQRAFELNTDDATGRTSLRLLPRFETITYRELWQRVGEVAAAWHHDPENPLRAGDFVALLGFTSIDYATLDLADIHLGAVTVPLQASAAVSQLIAILTETSPRLLASTPEHLDAAVECLLAGTTPERLVVFDYHPEDDDQRAAFESARRRLADAGSLVIVETLDAVRARGRDLPAAPLFVPDTDDDPLALLIYTSGSTGTPKGAMYTNRLAATMWQGNSMLQGNSQRVGINLNYMPMSHIAGRISLFGVLARGGTAYFAAKSDMSTLFEDIGLVRPTEIFFVPRVCDMVFQRYQSELDRRSVAGADLDTLDREVKADLRQNYLGGRFLVAVVGSAPLAAEMKTFMESVLDLPLHDGYGSTEAGASVLLDNQIQRPPVLDYKLVDVPELGYFRTDRPHPRGELLLKAETTIPGYYKRPEVTAEIFDEDGFYKTGDIVAELEHDRLVYVDRRNNVLKLSQGEFVTVAHLEAVFASSPLIRQIFIYGSSERSYLLAVIVPTDDALRGRDTATLKSALAESIQRIAKDANLQPYEIPRDFLIETEPFTIANGLLSGIAKLLRPNLKERYGAQLEQMYTDLAT 5mss A 1.96 BS01 AMP A 1 S408 A409 P410 D429 G430 Y431 G432 S433 T434 D507 Y519 K528 S387 A388 P389 D408 G409 Y410 G411 S412 T413 D486 Y498 K507 T265 F285 H315 T434 L529 K629 T249 F269 H294 T413 L508 K608 1.2.1.- 0001676,0004467,0005524,0006629,0016020,0016491,0016620,0031177,0050661 E5XP76 28719588 1201 QSLAERVARLVAIDPQAAAAVPDKAVAERATQQGLRLAQRIEAFLSGYGDRPALAQRAFEITKDPITGRAVATLLPKFETVSYRELLERSHAIASELANHAEAPVKAGEFIATIGFTSTDYTSLDIAGVLLGLTSVPLQTGATTDTLKAIAEETAPAVFGASVEHLDNAVTTALATPSVRRLLVFDYRQGVDEDREAVEAARSRLAEAGSAVLVDTLDEVIARGRALPRVALPPATDAGDDSLSLLIYTSGSTGTPKGAMYPERNVAQFWGGIWHNAFDPDVPDIMVNFMPLSHVAGRIGLMGTLSSGGTTYFIAKSDLSTFFEDYSLARPTKLFFVPRICEMIYQHYQSELDRIGAADGSPQAEAIKTELREKLLGGRVLTAGSGSAPMSPELTAFIESVLQVHLVDGYGSTEAGPVWRDRKLVKPPVTEHKLIDVPELGYFSTDSPYPRGELAIKTQTILPGYYKRPETTAEVFDEDGFYLTGDVVAEVAPEEFVYVDRRKNVLKLSQGEFVALSKLEAAYGTSPLVRQISVYGSSQRSYLLAVVVPTPEALAKYGDGEAVKSALGDSLQKIAREEGLQSYEVPRDFIIETDPFTIENGILSDAGKTLRPKVKARYGERLEALYAQLAETQAGELRSIRVGERPVIETVQRAAAALLGAVDPEAHFSDLGGDSLSALTYSNFLHEIFQVEVPVSVIVSAANNLRSVAAHIEKERS 5mst A 1.72 BS04 AMP A 1 H315 S408 A409 P410 G430 Y431 G432 S433 T434 D507 Y519 R522 K629 H295 S388 A389 P390 G410 Y411 G412 S413 T414 D487 Y499 R502 K609 T265 F285 H315 T434 L529 K629 T249 F265 H295 T414 L509 K609 1.2.1.- 0001676,0004467,0005524,0006629,0016020,0016491,0016620,0031177,0050661 E5XP76 28719588 1204 QSLAERVARLVAIDPQAAAAVPDKAVAERATQQGLRLAQRIEAFLSGYGDRPALAQRAFEITKDPITGRAVATLLPKFETVSYRELLERSHAIASELANHAEAPVKAGEFIATIGFTSTDYTSLDIAGVLLGLTSVPLQTGATTDTLKAIAEETAPAVFGASVEHLDNAVTTALATPSVRRLLVFDYRQGVDEDREAVEAARSRLAEAGSAVLVDTLDEVIARGRALPRVALPPATDAGDDSLSLLIYTSTPKGAMYPERNVAQFWGGIWHNAFDDGDSAPDVPDIMVNFMPLSHVAGRIGLMGTLSSGGTTYFIAKSDLSTFFEDYSLARPTKLFFVPRICEMIYQHYQSELDRIGAADGSPQAEAIKTELREKLLGGRVLTAGSGSAPMSPELTAFIESVLQVHLVDGYGSTEAGPVWRDRKLVKPPVTEHKLIDVPELGYFSTDSPYPRGELAIKTQTILPGYYKRPETTAEVFDEDGFYLTGDVVAEVAPEEFVYVDRRKNVLKLSQGEFVALSKLEAAYGTSPLVRQISVYGSSQRSYLLAVVVPTPEALAKYGDGEAVKSALGDSLQKIAREEGLQSYEVPRDFIIETDPFTIENGILSDAGKTLRPKVKARYGERLEALYAQLA 5mst B 1.72 BS04 AMP B 1 H315 S408 A409 P410 G430 Y431 G432 S433 T434 D507 Y519 R522 K629 H296 S389 A390 P391 G411 Y412 G413 S414 T415 D488 Y500 R503 K610 T265 F285 H315 T434 L529 K629 T249 F266 H296 T415 L510 K610 1.2.1.- 0001676,0004467,0005524,0006629,0016020,0016491,0016620,0031177,0050661 E5XP76 28719588 1204 QSLAERVARLVAIDPQAAAAVPDKAVAERATQQGLRLAQRIEAFLSGYGDRPALAQRAFEITKDPITGRAVATLLPKFETVSYRELLERSHAIASELANHAEAPVKAGEFIATIGFTSTDYTSLDIAGVLLGLTSVPLQTGATTDTLKAIAEETAPAVFGASVEHLDNAVTTALATPSVRRLLVFDYRQGVDEDREAVEAARSRLAEAGSAVLVDTLDEVIARGRALPRVALPPATDAGDDSLSLLIYTSGTPKGAMYPERNVAQFWGGIWHNAFDDGDSAPDVPDIMVNFMPLSHVAGRIGLMGTLSSGGTTYFIAKSDLSTFFEDYSLARPTKLFFVPRICEMIYQHYQSELDRIGAADGSPQAEAIKTELREKLLGGRVLTAGSGSAPMSPELTAFIESVLQVHLVDGYGSTEAGPVWRDRKLVKPPVTEHKLIDVPELGYFSTDSPYPRGELAIKTQTILPGYYKRPETTAEVFDEDGFYLTGDVVAEVAPEEFVYVDRRKNVLKLSQGEFVALSKLEAAYGTSPLVRQISVYGSSQRSYLLAVVVPTPEALAKYGDGEAVKSALGDSLQKIAREEGLQSYEVPRDFIIETDPFTIENGILSDAGKTLRPKVKARYGERLEALYAQLA 5msw A 2.33 BS01 AMP A 1 S408 A409 P410 G430 Y431 G432 T434 D507 Y519 R522 S381 A382 P383 G403 Y404 G405 T407 D480 Y492 R495 T265 F285 H315 T434 L529 K629 T248 F264 H288 T407 L502 K602 1.2.1.- 0001676,0004467,0005524,0006629,0016020,0016491,0016620,0031177,0050661 E5XP76 28719588 1201 QSLAERVARLVAIDPQAAAAVPDKAVAERATQQGLRLAQRIEAFLSGYGDRPALAQRAFEITKDPTGRAVATLLPKFETVSYRELLERSHAIASELANHAEAPVKAGEFIATIGFTSTDYTSLDIAGVLLGLTSVPLQTGATTDTLKAIAEETAPAVFGASVEHLDNAVTTALATPSVRRLLVFDYRQGVDEDREAVEAARSRLAEAGSAVLVDTLDEVIARGRALPRVALPPATDAGDDSLSLLIYTSTPKGAMYPERNVAQFWGGIWHNAFPDVPDIMVNFMPLSHVAGRIGLMGTLSSGGTTYFIAKSDLSTFFEDYSLARPTKLFFVPRICEMIYQHYQSELDRIGAADGSPQAEAIKTELREKLLGGRVLTAGSGSAPMSPELTAFIESVLQVHLVDGYGSTEAGPVWRDRKLVKPPVTEHKLIDVPELGYFSTDSPYPRGELAIKTQTILPGYYKRPETTAEVFDEDGFYLTGDVVAEVAPEEFVYVDRRKNVLKLSQGEFVALSKLEAAYGTSPLVRQISVYGSSQRSYLLAVVVPTPEALAKYGDGEAVKSALGDSLQKIAREEGLQSYEVPRDFIIETDPFTIENGILSDAGKTLRPKVKARYGERLEALYAQLAETQAGELRSIRVGAGERPVIETVQRAAAALLGASAAEVDPEAHFSDLGGDSLSALTYSNFLHEIFQVEVPVSVIVSAANNLRSVAAHIEKE 5n5u A 1.6 BS01 AMP A 1 F35 H42 G44 H45 Q48 G170 E172 V195 L196 M205 F35 H42 G44 H45 Q48 G170 E172 V195 L196 M205 6.1.1.1 0000166,0004812,0004831,0005524,0005737,0006412,0006418,0006437 Q57834 29668275 401 MDEFELIKRNTSEIISEEELREVLKKDEKSASIGFEPSGKIHLGHYLQIKKMIDLQNAGFDIIIALADLMAYLNQKGELDEIRKIGDYNKKVFEAMGLKAKYVYGSEFQLDKDYTLNVYRLALKTTLKRARRSMELIAREDENPKVAEVIYPIMQVNSIHYEGVDVAVGGMEQRKIHMLARELLPKKVVCIHNPVLTGLDGEGKMSSSKGNFIAVDDSPEEIRAKIKKAYCPAGVVEGNPIMEIAKYFLEYPLTIKRPEKFGGDLTVNSYEELESLFKNKELHPMRLKNAVAEELIKILEPIRKRLSAH 5nc8 A 3.09 BS01 AMP A 1 G415 R416 F417 D436 H437 G455 D456 A457 I478 D479 R503 G9 R10 F11 D30 H31 G45 D46 A47 I68 D69 R93 ? 0005886,0006813,0015079 Q12SB3 28656748 2401 NSVIIAGYGRFGQVVGRLLSAQGYHLSILDHSPSQIDMLNKVFYGDAARKDLLEAAGAKDAQLLVIAIDAPDKALEIVELAHKHYPQLKIVARAIDRRHAYQYLRLGVTSFKRETFDSAVNLGIEALTLLGNSSTVAERAGDLFSQHDNASLHELAALW 5nc8 B 3.09 BS01 AMP B 1 G415 R416 F417 D436 H437 G455 D456 A457 I478 D479 R503 G9 R10 F11 D30 H31 G43 D44 A45 I66 D67 R91 ? 0005886,0006813,0015079 Q12SB3 28656748 2401 NSVIIAGYGRFGQVVGRLLSAQGYHLSILDHSPSQIDNKVFYGDAARKDLLEAAGAKDAQLLVIAIDAPDKALEIVELAHKHYPQLKIVARAIDRRHAYQYLRLGVTSFKRETFDSAVNLGIEALTLLGNSSTVAERAGDLFSQHDNASLHELAALWG 5nrh A 1.3 BS01 AMP A 1 K104 F146 K148 E184 I187 E192 F214 Y215 E275 K102 F144 K146 E182 I185 E190 F212 Y213 E273 V25 N28 H70 H218 R260 G281 H285 V23 N26 H68 H216 R258 G279 H283 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q63QJ9 31260169 700 GIDPKRFGKVAVLLGGDSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDYAARAQDIVAKLGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSIEGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIARRAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGIGYSELVVKVLSLTLD 5nrh B 1.3 BS01 AMP B 1 K104 F146 K148 S155 E184 S186 I187 E192 F214 Y215 L274 E275 K101 F143 K145 S152 E181 S183 I184 E189 F211 Y212 L271 E272 V25 N28 H70 H218 R260 G281 H285 V22 N25 H67 H215 R257 G278 H282 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 Q63QJ9 31260169 700 IDPKRFGKVAVLLGGDSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDYAARAQDIVAKLGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSIEGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIARRAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGIGYSELVVKVLSLTLD 5nri A 1.5 BS01 AMP A 1 K104 F146 K148 E184 I187 E192 F214 Y215 E275 K103 F145 K147 E183 I186 E191 F213 Y214 E274 V25 N28 H70 H218 R260 G281 H285 V24 N27 H69 H217 R259 G280 H284 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 A3NZL3 31260169 401 SGIDPKRFGKVAVLLGGDSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDYAARAQDIVAKLGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSIEGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIARRAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGIGYSELVVKVLSLTLD 5nri B 1.5 BS01 AMP B 1 K104 F146 K148 S155 V158 E184 S186 I187 E192 F214 Y215 L274 E275 K101 F143 K145 S152 V155 E181 S183 I184 E189 F211 Y212 L271 E272 V25 N28 H70 H218 R260 G281 H285 V22 N25 H67 H215 R257 G278 H282 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 A3NZL3 31260169 404 IDPKRFGKVAVLLGGDSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDYAARAQDIVAKLGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSIEGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIARRAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGIGYSELVVKVLSLTLD 5nx9 A 2.3 BS01 AMP A 1 R85 H86 D87 S112 Q241 L331 S334 A335 R338 R77 H78 D79 S104 Q233 L317 S320 A321 R324 H86 T158 H159 K295 E302 H78 T150 H151 K281 E288 4.3.2.2 0000166,0003824,0004018,0005829,0006164,0006189,0009152,0009168,0016829,0044208,0070626 -logKd/Ki=4.60, Kd~25uM A0A384E0N4 30573755 503 SPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKA 5nx9 A 2.3 BS04 AMP D 1 R20 Y21 R303 R12 Y13 R289 H86 T158 H159 K295 E302 H78 T150 H151 K281 E288 4.3.2.2 0000166,0003824,0004018,0005829,0006164,0006189,0009152,0009168,0016829,0044208,0070626 -logKd/Ki=4.60, Kd~25uM A0A384E0N4 30573755 502 SPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKA 5nx9 D 2.3 BS01 AMP A 1 R20 Y21 R303 R13 Y14 R296 H86 T158 H159 S290 K295 E302 H79 T151 H152 S283 K288 E295 4.3.2.2 0000166,0003824,0004018,0005829,0006164,0006189,0009152,0009168,0016829,0044208,0070626 -logKd/Ki=4.60, Kd~25uM A0A384E0N4 30573755 503 GSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL 5nx9 D 2.3 BS04 AMP D 1 R85 H86 D87 S112 Q241 L331 S334 A335 R338 R78 H79 D80 S105 Q234 L324 S327 A328 R331 H86 T158 H159 S290 K295 E302 H79 T151 H152 S283 K288 E295 4.3.2.2 0000166,0003824,0004018,0005829,0006164,0006189,0009152,0009168,0016829,0044208,0070626 -logKd/Ki=4.60, Kd~25uM A0A384E0N4 30573755 502 GSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL 5o1u A 1.9 BS04 AMP A 1 H105 H263 S265 R267 G284 G285 H286 A290 G291 H107 H265 S267 R269 G286 G287 H288 A292 G293 ? 0000166,0003676,0046872 Q9X1T1 29107484 404 SGMDEIVKVLSQHDRILVVGHIMPDGDCVSSVLSLTLGLEKLGKEVKAAVDYKIPYVFEKFPYIDKIEENPNFDPELLVVVDASSPDRIGKFQDLLDKVPSVVIDHHSTNTNFGNWNWVDPSFAATAQMIFRINKALGVEYDSNLATLNYLGIATDTGFFRHSNADVRVFEDAYKLVKMGADAHFVAKEILENKRFEQFKLFAEVLERLQLLENGKIAYSYIDYDTYLRHNCTDEDSAGFVGELRSIRGVEVAVLFMEFPRGKIHVSMRSKDWFNVNEVAFELGGGGHPRAAGVTFEGKKIEEVIPRVINHLLKKFKEG 5o1u B 1.9 BS04 AMP B 1 H105 H263 S265 R267 G283 G284 G285 A290 G291 T293 H107 H265 S267 R269 G285 G286 G287 A292 G293 T295 ? 0000166,0003676,0046872 Q9X1T1 29107484 405 SGMDEIVKVLSQHDRILVVGHIMPDGDCVSSVLSLTLGLEKLGKEVKAAVDYKIPYVFEKFPYIDKIEENPNFDPELLVVVDASSPDRIGKFQDLLDKVPSVVIDHHSTNTNFGNWNWVDPSFAATAQMIFRINKALGVEYDSNLATLNYLGIATDTGFFRHSNADVRVFEDAYKLVKMGADAHFVAKEILENKRFEQFKLFAEVLERLQLLENGKIAYSYIDYDTYLRHNCTDEDSAGFVGELRSIRGVEVAVLFMEFPRGKIHVSMRSKDWFNVNEVAFELGGGGHPRAAGVTFEGKKIEEVIPRVINHLLKKFKEGVE 5o3r A 1.9 BS01 AMP A 1 G39 K40 G41 N59 A88 G89 I90 G38 K39 G40 N45 A74 G75 I76 ? 0005886,0006808,0009579,0030234,0031676 Kd=10.1uM -logKd/Ki=5.00, Kd=10.1uM P73954 29735650 201 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 5o3r A 1.9 BS02 AMP A 2 G31 Y32 T33 L65 H102 G30 Y31 T32 L51 H88 ? 0005886,0006808,0009579,0030234,0031676 Kd=10.1uM -logKd/Ki=5.00, Kd=10.1uM P73954 29735650 202 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 5o3r B 1.9 BS01 AMP A 1 G31 Y32 T33 I64 L65 H102 G30 Y31 T32 I51 L52 H89 ? 0005886,0006808,0009579,0030234,0031676 -logKd/Ki=5.00, Kd=10.1uM P73954 29735650 201 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGCSAWS 5o3r B 1.9 BS02 AMP C 1 N59 A88 G89 I90 N46 A75 G76 I77 ? 0005886,0006808,0009579,0030234,0031676 -logKd/Ki=5.00, Kd=10.1uM P73954 29735650 200 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGCSAWS 5o3r C 1.9 BS01 AMP A 2 V11 G39 K40 G41 N59 A88 G89 I90 V10 G38 K39 G40 N44 A73 G74 I75 ? 0005886,0006808,0009579,0030234,0031676 Kd=10.1uM P73954 29735650 202 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGCSAWS 5o3r C 1.9 BS02 AMP C 1 L65 H102 T103 L50 H87 T88 ? 0005886,0006808,0009579,0030234,0031676 Kd=10.1uM P73954 29735650 200 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGCSAWS 5o70 A 1.55 BS01 AMP A 1 H263 S265 R267 G283 G284 H286 A289 A290 G291 T293 H266 S268 R270 G286 G287 H289 A292 A293 G294 T296 ? 0000166,0003676,0046872 Q9X1T1 29107484 401 GSGMDEIVKVLSQHDRILVVGHIMPDGDCVSSVLSLTLGLEKLGKEVKAAVDYKIPYVFEKFPYIDKIEENPNFDPELLVVVNASSPDRIGKFQDLLDKVPSVVIDHHSTNTNFGNWNWVDPSFAATAQMIFRINKALGVEYDSNLATLNYLGIATNTGFFRHSNADVRVFEDAYKLVKMGADAHFVAKEILENKRFEQFKLFAEVLERLQLLENGKIAYSYIDYDTYLRHNCTDEDSAGFVGELRSIRGVEVAVLFMEFPRGKIHVSMRSKDWFNVNEVAFELGGGGHPRAAGVTFEGKKIEEVIPRVINHLLKKFKEGVES 5o70 A 1.55 BS02 AMP A 2 H104 H105 N154 H160 S161 N162 H286 A289 H107 H108 N157 H163 S164 N165 H289 A292 ? 0000166,0003676,0046872 Q9X1T1 29107484 402 GSGMDEIVKVLSQHDRILVVGHIMPDGDCVSSVLSLTLGLEKLGKEVKAAVDYKIPYVFEKFPYIDKIEENPNFDPELLVVVNASSPDRIGKFQDLLDKVPSVVIDHHSTNTNFGNWNWVDPSFAATAQMIFRINKALGVEYDSNLATLNYLGIATNTGFFRHSNADVRVFEDAYKLVKMGADAHFVAKEILENKRFEQFKLFAEVLERLQLLENGKIAYSYIDYDTYLRHNCTDEDSAGFVGELRSIRGVEVAVLFMEFPRGKIHVSMRSKDWFNVNEVAFELGGGGHPRAAGVTFEGKKIEEVIPRVINHLLKKFKEGVES 5ofu A 2.62 BS01 AMP A 1 I16 S19 Q20 P21 S24 R25 G26 F28 Y113 I10 S13 Q14 P15 S18 R19 G20 F22 Y97 D74 E97 E98 D118 L120 D121 E284 D58 E81 E82 D102 L104 D105 E268 3.1.3.11 0000166,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0020015,0030388,0042132,0042578,0046872 -logKd/Ki=4.20, Ki=63.8uM O97193 28882541 401 PTPTTLTQYIIKSQPPHSRGDFTLLMMAIQTSVKVIEKNIRRAGMKGMLGYIAGAKLDVISNIAFKAYLLSSTSVCVLGSEEEEQMIIAESGRRGDYLIFFDPLDGSSNIDANVSVGSIWGVWRLPKDTTINSVEDANAVIRMLKGTDMVSAGYAVYGSATNLVLTSGHGVDGFTLDPNIGEFILTHPHISIPKKRSIYSVNEGNYGKWEPWFKEYIDYLKMNKTTRYSARYIGSMVGDIHRTLLYGGIFCYPKDANQVEGKLRLLYEAAPMAMIVEQAGGKAVGSNGRILEQSITRLHQRTPVYFGSRQEVDLCMAFRDRN 5ofu B 2.62 BS01 AMP B 1 S19 Q20 P21 S24 R25 G26 F28 Y113 S183 S13 Q14 P15 S18 R19 G20 F22 Y97 S167 D74 E97 E98 D118 L120 D121 E284 D58 E81 E82 D102 L104 D105 E268 3.1.3.11 0000166,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0020015,0030388,0042132,0042578,0046872 O97193 28882541 401 PTPTTLTQYIIKSQPPHSRGDFTLLMMAIQTSVKVIEKNIRRAGMKGMLGYIAGAKLDVISNIAFKAYLLSSTSVCVLGSEEEEQMIIAESGRRGDYLIFFDPLDGSSNIDANVSVGSIWGVWRLPKDTTINSVEDANAVIRMLKGTDMVSAGYAVYGSATNLVLTSGHGVDGFTLDPNIGEFILTHPHISIPKKRSIYSVNEGNYGKWEPWFKEYIDYLKMNKTTRYSARYIGSMVGDIHRTLLYGGIFCYPKDANQVEGKLRLLYEAAPMAMIVEQAGGKAVGSNGRILEQSITRLHQRTPVYFGSRQEVDLCMAFRDRN 5ofu C 2.62 BS01 AMP C 1 I16 S19 Q20 P21 S24 R25 G26 F28 Y113 S183 I10 S13 Q14 P15 S18 R19 G20 F22 Y93 S163 D74 E97 E98 D118 L120 D121 E284 D55 E78 E79 D98 L100 D101 E264 3.1.3.11 0000166,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0020015,0030388,0042132,0042578,0046872 O97193 28882541 401 PTPTTLTQYIIKSQPPHSRGDFTLLMMAIQTSVKVIEKNIRRAGMKGMLGYAKLDVISNIAFKAYLLSSTSVCVLGSEEEEQMIIAESRRGDYLIFFDPLDGSSNIDANVSVGSIWGVWRLPKDTTINSVEDANAVIRMLKGTDMVSAGYAVYGSATNLVLTSGHGVDGFTLDPNIGEFILTHPHISIPKKRSIYSVNEGNYGKWEPWFKEYIDYLKMNKTTRYSARYIGSMVGDIHRTLLYGGIFCYPKDANQVEGKLRLLYEAAPMAMIVEQAGGKAVGSNGRILEQSITRLHQRTPVYFGSRQEVDLCMAFRDR 5ofu D 2.62 BS01 AMP D 1 I16 S19 Q20 P21 R25 G26 F28 Y113 S183 I10 S13 Q14 P15 R19 G20 F22 Y96 S166 D74 E97 E98 D118 L120 D121 E284 D57 E80 E81 D101 L103 D104 E267 3.1.3.11 0000166,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0016787,0016791,0020015,0030388,0042132,0042578,0046872 O97193 28882541 401 PTPTTLTQYIIKSQPPHSRGDFTLLMMAIQTSVKVIEKNIRRAGMKGMLGYIAAKLDVISNIAFKAYLLSSTSVCVLGSEEEEQMIIAESGRRGDYLIFFDPLDGSSNIDANVSVGSIWGVWRLPKDTTINSVEDANAVIRMLKGTDMVSAGYAVYGSATNLVLTSGHGVDGFTLDPNIGEFILTHPHISIPKKRSIYSVNEGNYGKWEPWFKEYIDYLKMNKTTRYSARYIGSMVGDIHRTLLYGGIFCYPKDANQVEGKLRLLYEAAPMAMIVEQAGGKAVGSNGRILEQSITRLHQRTPVYFGSRQEVDLCMAFRDRN 5ow0 B 1.7 BS01 AMP B 1 L6 A7 K8 D39 Y62 I95 A114 G115 Q117 S118 R123 G124 V125 V126 P127 L6 A7 K8 D39 Y62 I95 A114 G115 Q117 S118 R123 G124 V125 V126 P127 ? 0000166,0009055 Q39VG5 31405915 301 MQIVVLAKVVPDYEVPSADFELVGNRAHPRYTRMIGLYDENAVELGVQLKEKLGADLTVVSYGRNDDVQFLRKALAMGADKVVLVEGDSDDPYVIAANLKDAIDRQGTVDLILAGRQSSDMDRGVVPGVLAGMLDLPFVPQACSVESVDGGWKISQITETGKRLLKLSGKGVLSITSVPENVPRIPAVKAIFAAKKKPVEKLPEIGTGKMAVSELSVSIPKVESNCELIPAEDMDDAVRVLLRRLKEERYL 5svb B 2.645 BS01 AMP B 1 T21 G311 G312 A352 L400 F405 L406 G473 A474 D692 A693 T694 T695 T14 G304 G305 A345 L393 F398 L399 G466 A467 D682 A683 T684 T685 6.4.1.6 0005524,0005829,0006749,0016787,0016874,0017168,0018710,0140977 Q8RM04 28775283 801 LRNVQVLGIDAGGTMTDTFFVDQDGDFVVGKAQSTPQNEALGLIASSEDGLANWGMSLHEALAQLQTGVYSGTAMLNRVVQRKGLKCGLIVNRGMEDFHRMGRAVQSHLGYAYEDRIHLNTHRYDPPLVPRHLTRGVVERTDMIGTQVIPLREDTARDAARDLIAADAEGIVISLLHSYKNPENERRVRDIVLEEVEKSGKKIPVFASADYYPVRKETHRTNTTILEGYAAEPSRQTLSKISNAFKERGTKFDFRVMATHGGTISWKAKELARTIVSGPIGGVIGAKYLGEVLGYKNIACSDIGGTSFDVALITQGEMTIKNDPDMARLVLSLPLVAMDSVGAGAGSFIRLDPYTRAIKLGPDSAGYRVGVCWKESGIETVTISDCHMVLGYLNPDNFLGGAVKLDRQRSVDAIKAQIADPLGLSVEDAAAGVIELLDSDLRDYLRSMISGKGYSPASFVCFSYGGAGPVHTYGYTEGLGFEDVIVPAWAAGFSAFGCAAADFEYRYDKSLDINMPTETPDTDKEKAAATLQAAWEELTKNVLEEFKLNGYSADQVTLQPGYRMQYRGQLNDLEIESPLAQAHTAADWDQLTDAFNATYGRVYARSPELGYSVTGAIMRGMVPIPKPKIPKEPEEGETPPESAKIGTRKFYRKKRWVDAQLYHMESLRPGNRVMGPAVIESDATTFVVPDGFETWLDGHRLFHLREV 5svb E 2.645 BS01 AMP E 1 T21 K38 G311 G312 L400 F405 L406 G473 A474 D692 A693 T694 T695 T14 K31 G304 G305 L393 F398 L399 G466 A467 D682 A683 T684 T685 6.4.1.6 0005524,0005829,0006749,0016787,0016874,0017168,0018710,0140977 Q8RM04 28775283 801 LRNVQVLGIDAGGTMTDTFFVDQDGDFVVGKAQSTPQNEALGLIASSEDGLANWGMSLHEALAQLQTGVYSGTAMLNRVVQRKGLKCGLIVNRGMEDFHRMGRAVQSHLGYAYEDRIHLNTHRYDPPLVPRHLTRGVVERTDMIGTQVIPLREDTARDAARDLIAADAEGIVISLLHSYKNPENERRVRDIVLEEVEKSGKKIPVFASADYYPVRKETHRTNTTILEGYAAEPSRQTLSKISNAFKERGTKFDFRVMATHGGTISWKAKELARTIVSGPIGGVIGAKYLGEVLGYKNIACSDIGGTSFDVALITQGEMTIKNDPDMARLVLSLPLVAMDSVGAGAGSFIRLDPYTRAIKLGPDSAGYRVGVCWKESGIETVTISDCHMVLGYLNPDNFLGGAVKLDRQRSVDAIKAQIADPLGLSVEDAAAGVIELLDSDLRDYLRSMISGKGYSPASFVCFSYGGAGPVHTYGYTEGLGFEDVIVPAWAAGFSAFGCAAADFEYRYDKSLDINMPTETPDTDKEKAAATLQAAWEELTKNVLEEFKLNGYSADQVTLQPGYRMQYRGQLNDLEIESPLAQAHTAADWDQLTDAFNATYGRVYARSPELGYSVTGAIMRGMVPIPKPKIPKEPEEGETPPESAKIGTRKFYRKKRWVDAQLYHMESLRPGNRVMGPAVIESDATTFVVPDGFETWLDGHRLFHLREV 5sxs B 1.887 BS05 AMP B 1 D222 A252 R255 D187 A217 R220 R108 H112 H279 W330 D389 R73 H77 H244 W295 D354 1.11.1.21 0004096,0004601,0005829,0006979,0020037,0042744,0046872,0070301,0098869 Q3JNW6 20554537 809 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5t5t C 3.46 BS01 AMP C 1 H150 T199 I203 A204 V224 S225 H297 I311 S313 S315 D316 H125 T174 I178 A179 V199 S200 H268 I282 S284 S286 D287 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 28289077 401 SVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHREGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 5t5t C 3.46 BS02 AMP C 2 I239 S241 F243 D244 R268 L276 V296 H297 R298 I214 S216 F218 D219 R243 L247 V267 H268 R269 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 28289077 402 SVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHREGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 5t8s A 1.7 BS01 AMP A 1 H15 P16 D166 K168 S191 F235 D243 H14 P15 D165 K167 S190 F234 D242 H15 D17 K18 E43 E56 K168 F235 D243 C244 R249 K250 K270 K274 D276 H14 D16 K17 E42 E55 K167 F234 D242 C243 R248 K249 K269 K273 D275 2.5.1.6 0000287,0004478,0005524,0005737,0005829,0006556,0006730,0016740,0046872 Q5FAC0 402 SEYLFTSESVSEGHPDKVADQVSDAILDAILAQDPKARVAAETLVNTGLCVLAGEITTTAQVDYIKVARETIKRIGYNSSELGFDANGCAVGVYYDQQSPDIAQGVNEGEGIDLNQGAGDQGLMFGYACDETPTLMPFAIYYSHRLMQRQSELRKDGRLPWLRPDAKAQLTVVYDSETGKVKRIDTVVLSTQHDPAISQEELSKAVIEQIIKPVLPPELLTDETKYLINPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYACRYVAKNIVAAGLATQCQIQVSYAIGVAEPTSISIDTFGTGKISEEKLIALVCEHFDLRPKGIVQMLDLLRPIYGKSAAYGHFGREEPEFTWERTDKAASLKAAAGL 5t8t A 2.1 BS01 AMP B 1 D102 I103 D121 D101 I102 D111 H15 D17 K18 E43 E56 K168 F235 D243 C244 R249 K250 K270 K274 D276 H14 D16 K17 E42 E55 K158 F225 D233 C234 R239 K240 K260 K264 D266 2.5.1.6 0000287,0004478,0005524,0005737,0005829,0006556,0006730,0016740,0046872 Q5FAC0 401 SEYLFTSESVSEGHPDKVADQVSDAILDAILAQDPKARVAAETLVNTGLCVLAGEITTTAQVDYIKVARETIKRIGYNSSELGFDANGCAVGVYYDQQSPDIADLNQGAGDQGLMFGYACDETPTLMPFAIYYSHRLMQRQSELRKDGRLPWLRPDAKAQLTVVYDSETGKVKRIDTVVLSTQHDPAISQEELSKAVIEQIIKPVLPPELLTDETKYLINPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYACRYVAKNIVAAGLATQCQIQVSYAIGVAEPTSISIDTFGTGKISEEKLIALVCEHFDLRPKGIVQMLDLLRPIYGKSAAYGHFGREEPEFTWERTDKAASLKAAAGL 5t8t B 2.1 BS01 AMP B 1 H15 D166 K168 S191 T232 F235 D243 K250 H14 D153 K155 S178 T219 F222 D230 K237 H15 D17 K18 E43 E56 K168 F235 D243 C244 R249 K250 K270 K274 D276 H14 D16 K17 E42 E55 K155 F222 D230 C231 R236 K237 K257 K261 D263 2.5.1.6 0000287,0004478,0005524,0005737,0005829,0006556,0006730,0016740,0046872 Q5FAC0 401 SEYLFTSESVSEGHPDKVADQVSDAILDAILAQDPKARVAAETLVNTGLCVLAGEITTTAQVDYIKVARETIKRIGYNSSELGFDANGCAVGVYYDQQSPDLNQGAGDQGLMFGYACDETPTLMPFAIYYSHRLMQRQSELRKDGRLPWLRPDAKAQLTVVYDSETGKVKRIDTVVLSTQHDPAISQEELSKAVIEQIIKPVLPPELLTDETKYLINPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYACRYVAKNIVAAGLATQCQIQVSYAIGVAEPTSISIDTFGTGKISEEKLIALVCEHFDLRPKGIVQMLDLLRPIYGKSAAYGHFGREEPEFTWERTDKAASLKAAAG 5tva A 2.25 BS01 AMP A 1 M112 G114 A115 R135 T136 D183 R215 Y217 M111 G113 A114 R134 T135 D182 R214 Y216 6.2.1.14 0000287,0005524,0009102,0016874,0042410 O67575 28414711 301 DLFSVRMRAQKNGKHVSGAERIVKKEELETAVKELLNRPKEFDFMNVKVEKVKDFEVVKFNLKISTYSFKSPEEAREFAVKKLTQEGIKEEVAKKAVEILSKGANPKGGNMRGAVLMDIETGERLEEDKERGVRTIHFDWKDRKKVTEKLLKEGYTLRTVDALALTFKNLFCGVVAELCWSDDPDYVTGYVSGKEIGYVRITPLKEKGDPLGGRVYFVSRKELSEIIECLTQKVVLIEL 5tva B 2.25 BS01 AMP B 1 M112 R113 G114 A115 R135 T136 R159 S182 D183 G214 R215 Y217 M111 R112 G113 A114 R134 T135 R158 S181 D182 G213 R214 Y216 6.2.1.14 0000287,0005524,0009102,0016874,0042410 O67575 28414711 500 DLFSVRMRAQKNGKHVSGAERIVKKEELETAVKELLNRPKEFDFMNVKVEKVKDFEVVKFNLKISTYSFKSPEEAREFAVKKLTQEGIKEEVAKKAVEILSKGANPKGGNMRGAVLMDIETGERLEEDKERGVRTIHFDWKDRKKVTEKLLKEGYTLRTVDALALTFKNLFCGVVAELCWSDDPDYVTGYVSGKEIGYVRITPLKEKGDPLGGRVYFVSRKELSEIIECLTQKVVLIE 5u7v A 2.15 BS01 AMP A 1 S15 T16 R19 Y303 D307 F350 S11 T12 R15 Y295 D299 F342 3.6.1.5 0004050,0005524,0016787 B9U139 28543850 501 TSYAVVFDAGSTGSRVHVYHFDQNLDLLHIGKDVEFYNKIQPGLSAYADNPEQAAKSLIPLLEQAENVVPEDFHSKTPIRLGATAGLRLLDGDASERILQAVRDMLNNKSTFNVQPDAVSIIDGTQEGSYLWVTINYVLGNLGKRFTNTVGVIDLGGGSVQMAYAVSKKTARNAPKVEDPYIKKIVLGKPYDLYVHSYLHFGREASRAEILKVTHGSASPCILAGFDGIYTYSGEEFKASAPTSGANFDKCKKIIQKALKLDYPCPYQNCTFGGIWNGGGGSGQKKLFAASSFFYLPQDVGMVDPNKSNLKLRPVDLENKAKIVCTLNVEDVKSAYPLLEKFNIVPYACMDLIYQYELLVDGFGLDPLQEITAGEKIEYQEALVDAAWALGNAVEAVLL 5udt A 3.188 BS01 AMP A 1 A24 S26 A52 F104 D122 G123 R133 A22 S24 A50 F102 D120 G121 R131 4.4.1.37 0005524,0016783,0016829 F9UST4 28784764 501 TLATKKATLVAALKDLQRVTVAFSGGIDSTLVLKMALDVLGRDNVTAVVANSELFTDEEFDKAMSLAEELGANVQGTTLDYLSDDHIKNNTPDSWYYAKKMFYSRLNDIAANNGSAAVLDGMIKNDENDYRPGLKARSEAGARSLLQEADFFKTDVRALAQELGLTNWNKVASCSVSSRFPYGTTLTHDNIAQVMAAEKYLRSLGFPTVRVRFHNDIARIELPEARIGDFLVFNDRVNRQLQSLGFRYVTLDLGGF 5udt B 3.188 BS01 AMP B 1 A24 F25 S26 S31 A52 F104 D122 G123 M124 A23 F24 S25 S30 A51 F103 D121 G122 M123 4.4.1.37 0005524,0016783,0016829 F9UST4 28784764 501 ATLATKKATLVAALKDLQRVTVAFSGGIDSTLVLKMALDVLGRDNVTAVVANSELFTDEEFDKAMSLAEELGANVQGTTLDYLSDDHIKNNTPDSWYYAKKMFYSRLNDIAANNGSAAVLDGMIKNPGLKARSEAGARSLLQEADFFKTDVRALAQELGLTNWNKVASCSVSSRFPYGTTLTHDNIAQVMAAEKYLRSLGFPTVRVRFHNDIARIELPEARIGDFLVFNDRVNRQLQSLGFRYVTLDLGGFR 5udt C 3.188 BS01 AMP C 1 A24 F25 S26 A52 K101 F104 D122 G123 R133 A22 F23 S24 A50 K99 F102 D120 G121 R131 4.4.1.37 0005524,0016783,0016829 F9UST4 28784764 501 TLATKKATLVAALKDLQRVTVAFSGGIDSTLVLKMALDVLGRDNVTAVVANSELFTDEEFDKAMSLAEELGANVQGTTLDYLSDDHIKNNTPDSWYYAKKMFYSRLNDIAANNGSAAVLDGMIKNDENDYRPGLKARSEAGARSLLQEADFFKTDVRALAQELGLTNWNKVASCSVSSRFPYGTTLTHDNIAQVMAAEKYLRSLGFPTVRVRFHNDIARIELPEARIGDFLVFNDRVNRQLQSLGFRYVTLDLGGF 5ufu C 3.45 BS01 AMP C 1 H150 T199 I203 A204 V224 S225 I311 S313 S315 D316 H122 T171 I175 A176 V196 S197 I278 S280 S282 D283 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 28467931 401 SVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 5ufu C 3.45 BS02 AMP C 2 R69 S241 F243 D244 R268 V275 L276 V296 H297 R298 R44 S213 F215 D216 R240 V242 L243 V263 H264 R265 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 28467931 402 SVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 5v0i A 1.9 BS01 AMP A 1 G19 N20 A24 V186 K195 M196 K198 G15 N16 A20 V173 K182 M183 K185 K195 K198 K182 K185 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0005829,0006412,0006418,0006436 P67589 401 KPIVFSGAQPSLTIGNYMGALRQWVNMQDDYHCIYCIVDQHAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFGELSRMTAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDIAQRFNALYGDIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVKKIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGEVADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLKAVYEAIGFVAKP 5v0i B 1.9 BS01 AMP B 1 G19 N20 V186 G18 N19 V177 K195 K198 K186 K189 6.1.1.2 0000166,0004812,0004830,0005524,0005737,0005829,0006412,0006418,0006436 P67589 401 TKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQHAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFGELSRMTQFKARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDIAQRFNALYGDIFKVPEPFARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVKKIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGEVADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLKAVYEAIGFVAKP 5veo A 1.53 BS05 AMP A 1 D36 A72 Y73 L106 M109 Y157 E159 Y186 E188 H339 D10 A46 Y47 L80 M83 Y131 E133 Y160 E162 H313 3.1.-.- 0000210,0004551,0005576,0005886,0007154,0008270,0009166,0016020,0016787,0046872 Q9EQG7 28898552 524 EQKVLVVSFDGFRWDYLYKVPTPHFHYIMKNGVHVNQVTNVFITKAYPNHYTLVTGLFAENHGIVANDMFDPILNKSFSLEHMDIYDSKFWEEATPIWITNQRAGHASGAAMWPGADVKIHDSFPTYYLPYNESVSFEDRVAKIIEWFTAKDPINLGFLYWEEPDDTGHDVGPDSPLMGSVISDVDHKLGYLIKMLKRAKLWNNVNLIVTSDHGMTQCSKQRVIELDRYLDKEHYTLIDHSPVAAILPKEGKFDEVYDALAGAHPNLTVYKKEEIPERWHYKHNDRVQPIVAVADEGWYILQNKSDDFLLGNHGYDNALAEMHPIFLAHGPAFRKNFTKEAMNSTDLYSLLCHLLNLTALPHNGSFWNVQDLLS 5wm2 A 1.548 BS01 AMP A 1 G328 S329 K330 V350 F351 G352 M353 A354 E355 D434 V446 K451 K460 G310 S311 K312 V332 F333 G334 M335 A336 E337 D416 V428 K433 K442 S211 N231 H255 A354 E355 N455 K460 K542 S193 N213 H237 A336 E337 N437 K442 K524 ? 0000166,0003824,0016874,0046872 A0A140DJY3 29742306 602 SHMLDGWVPWPESFARRYRAAGYWEGRPLDRLLRERAAADPDRIALVDAAGDRWTYAELDRHADRQAAGLRRLGIGAGDRVVVQLPNTDAFVVLFFALLRAGAVPVLTLPAHRESEIVHVAETAGATAYVIPDVLDGFDHRALARAARKAVPSIEHVLVAGEAAEFTALADVDAAPVPLAEPDPGDVALLLLSGGTTGKPKLIPRTHDDYTYNVRASAEVCGFDSDTVYLVVLPTAHNFALACPGLLGTLMVGGTVVLAPTPSPEDAFELIEREKVTATAVVPPVALLWLDAVEWEDADLSSLRLLQVGGSKLGAEPAARVRPALGCTLQQVFGMAEGLLNYTRLDDPSDLVIQTQGRPLSPDDEIRVVDEDGRDVAPGETGELLTRGPYTLRGYYRAPEHNARTFSDDGFYRTGDLVRVLPSGHLVVEGRAKDQINRGGDKISAEELENHIMAHPGVHDAAVVGMPDATMGERTCACLVPRAGRSAPAQRELAAFLTDRGVAAYKLPDRVEVMDAFPRTSVGKTDKKELGRRIAG 5wm7 A 1.777 BS01 AMP A 1 G328 S329 K330 V350 F351 G352 M353 D434 K451 K460 G310 S311 K312 V332 F333 G334 M335 D416 K433 K442 S211 N231 H255 A354 E355 N455 K460 K542 S193 N213 H237 A336 E337 N437 K442 K524 ? 0000166,0003824,0016874,0046872 A0A140DJY3 29742306 601 SHMLDGWVPWPESFARRYRAAGYWEGRPLDRLLRERAAADPDRIALVDAAGDRWTYAELDRHADRQAAGLRRLGIGAGDRVVVQLPNTDAFVVLFFALLRAGAVPVLTLPAHRESEIVHVAETAGATAYVIPDVLDGFDHRALARAARKAVPSIEHVLVAGEAAEFTALADVDAAPVPLAEPDPGDVALLLLSGGTTGKPKLIPRTHDDYTYNVRASAEVCGFDSDTVYLVVLPTAHNFALACPGLLGTLMVGGTVVLAPTPSPEDAFELIEREKVTATAVVPPVALLWLDAVEWEDADLSSLRLLQVGGSKLGAEPAARVRPALGCTLQQVFGMAEGLLNYTRLDDPSDLVIQTQGRPLSPDDEIRVVDEDGRDVAPGETGELLTRGPYTLRGYYRAPEHNARTFSDDGFYRTGDLVRVLPSGHLVVEGRAKDQINRGGDKISAEELENHIMAHPGVHDAAVVGMPDATMGERTCACLVPRAGRSAPAQRELAAFLTDRGVAAYKLPDRVEVMDAFPRTSVGKTDKKELGRRIA 5ws9 A 1.9 BS03 AMP A 1 R351 F373 T374 Q375 S376 T379 K418 M419 M425 G450 G454 G457 S458 T459 R350 F372 T373 Q374 S375 T378 K417 M418 M424 G449 G453 G456 S457 T458 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 29215013 503 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5ws9 B 1.9 BS03 AMP B 1 R351 F373 T374 Q375 S376 T379 W398 K418 M419 M425 G450 G454 G457 S458 T459 R350 F372 T373 Q374 S375 T378 W397 K417 M418 M424 G449 G453 G456 S457 T458 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 29215013 503 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5ws9 C 1.9 BS03 AMP C 1 R351 F373 T374 Q375 S376 T379 K418 M419 M425 G450 G454 G457 S458 T459 R350 F372 T373 Q374 S375 T378 K417 M418 M424 G449 G453 G456 S457 T458 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 29215013 504 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5ws9 D 1.9 BS03 AMP D 1 R351 F373 T374 Q375 S376 T379 K418 M419 M425 G450 G454 G457 S458 T459 R350 F372 T373 Q374 S375 T378 K417 M418 M424 G449 G453 G456 S457 T458 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 29215013 504 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsb A 2.25 BS01 AMP A 1 R351 F373 T374 Q375 S376 T379 A397 M419 M425 G450 G454 G457 S458 T459 R350 F372 T373 Q374 S375 T378 A396 M418 M424 G449 G453 G456 S457 T458 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 29215013 501 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsb B 2.25 BS01 AMP B 1 R351 F373 T374 Q375 S376 T379 W398 M419 M425 G450 G454 T455 G457 S458 T459 R350 F372 T373 Q374 S375 T378 W397 M418 M424 G449 G453 T454 G456 S457 T458 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 29215013 501 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsb C 2.25 BS01 AMP C 1 R351 F373 T374 Q375 S376 T379 M419 G450 G454 G457 S458 T459 R350 F372 T373 Q374 S375 T378 M418 G449 G453 G456 S457 T458 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 29215013 501 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsb D 2.25 BS01 AMP D 1 R351 F373 T374 Q375 S376 T379 K418 M419 G450 G454 G457 S458 T459 R350 F372 T373 Q374 S375 T378 K417 M418 G449 G453 G456 S457 T458 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 29215013 501 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsc A 2.4 BS01 AMP A 1 R351 F373 T374 Q375 S376 T379 M419 G450 G454 G457 S458 T459 R350 F372 T373 Q374 S375 T378 M418 G449 G453 G456 S457 T458 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 29215013 501 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsc B 2.4 BS01 AMP B 1 R351 T374 Q375 S376 T379 W398 M419 M425 G450 P453 G454 G457 S458 T459 R350 T373 Q374 S375 T378 W397 M418 M424 G449 P452 G453 G456 S457 T458 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 29215013 501 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsc C 2.4 BS01 AMP C 1 R351 T374 Q375 S376 T379 W398 M419 M425 G450 G454 G457 S458 T459 R350 T373 Q374 S375 T378 W397 M418 M424 G449 G453 G456 S457 T458 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 29215013 501 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsc D 2.4 BS01 AMP D 1 R351 F373 T374 Q375 S376 T379 K418 M419 G450 G454 G457 S458 T459 R350 F372 T373 Q374 S375 T378 K417 M418 G449 G453 G456 S457 T458 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 29215013 501 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5x0b A 1.75 BS01 AMP A 1 F40 S43 I49 F50 W51 K52 G70 H72 R73 F39 S42 I48 F49 W50 K51 G69 H71 R72 2.7.1.226 0005524,0016301,0016310,0019344 Q5JD03 28358477 301 GVEKVPKYDIPTKKVDYVFIELDKMKPHEQLVQKELEAFIESVTGSGIFWKPMLLAKVPGEDMYLIVDGHHRWAGLQKLGAKRAPSVILDYFSDDVKVYTWYPAFKGDLNEVVERLKKEGLEVIEDPEAEEKAERGEIAFALVGEKSFAIPGGLEEQKKVSKVLDEMSVEGKIELIYYGLKEDAREDMAKGEIDYVFIRKAPTKEEVMELVKRGEVYSPKTTRHVLPFNPDKIDVKLEELF 5x0e A 2.0 BS01 AMP A 1 F40 S43 I49 F50 W51 K52 G70 H72 R73 F39 S42 I48 F49 W50 K51 G69 H71 R72 2.7.1.226 0005524,0016301,0016310,0019344 Q5JD03 28358477 301 GVEKVPKYDIPTKKVDYVFIELDKMKPHAQLVQKELEAFIESVTGSGIFWKPMLLAKVPGEDMYLIVDGHHRWAGLQKLGAKRAPSVILDYFSDDVKVYTWYPAFKGDLNEVVERLKKEGLEVIEDPEAEEKAERGEIAFALVGEKSFAIPGGLEEQKKVSKVLDEMSVEGKIELIYYGLKEDAREDMAKGEIDYVFIRKAPTKEEVMELVKRGEVYSPKTTRHVLPFNPDKIDVKLEELF 5x0f A 1.76 BS01 AMP A 1 F40 S43 I49 F50 W51 K52 G70 H72 R73 F39 S42 I48 F49 W50 K51 G69 H71 R72 2.7.1.226 0005524,0016301,0016310,0019344 Q5JD03 28358477 301 GVEKVPKYDIPTKKVDYVFIELDKMKPHAQLVQKELEAFIESVTGSGIFWKPMLLAKVPGEDMYLIVDGHHRWAGLQKLGAKRAPSVILDYFSDDVKVYTWYPAFKGDLNEVVERLKKEGLEVIEDPEAEEKAERGEIAFALVGEKSFAIPGGLEEQKKVSKVLDEMSVEGKIELIYYGLKEDAREDMAKGEIDYVFIRKAPTKEEVMELVKRGEVYSPKTTRHVLPFNPDKIDVKLEELF 5x0g A 1.9 BS01 AMP A 1 F40 S43 I49 F50 W51 K52 G70 H72 R73 F38 S41 I47 F48 W49 K50 G68 H70 R71 2.7.1.226 0005524,0016301,0016310,0019344 Q5JD03 28358477 301 VEKVPKYDIPTKKVDYVFIELDKMKPHAQLVQKELEAFIESVTGSGIFWKPMLLAKVPGEDMYLIVDGHHRWAGLQKLGAKRAPSVILDYFSDDVKVYTWYPAFKGDLNEVVERLKKEGLEVIEDPEAEEKAERGEIAFALVGEKSFAIPGGLEEQKKVSKVLDEMSVEGKIELIYYGLKEDAREDMAKGIDYVFIRKAPTKEEVMELVKRGEVYSPKTTRHVLPFNPDKIDVKLEELF 5x0j A 1.43 BS01 AMP A 1 F40 S43 I49 F50 W51 K52 G70 H71 H72 R73 F39 S42 I48 F49 W50 K51 G69 H70 H71 R72 2.7.1.226 0005524,0016301,0016310,0019344 Q5JD03 28358477 301 GVEKVPKYDIPTKKVDYVFIELDKMKPHQQLVQKELEAFIESVTGSGIFWKPMLLAKVPGEDMYLIVDGHHRWAGLQKLGAKRAPSVILDYFSDDVKVYTWYPAFKGDLNEVVERLKKEGLEVIEDPEAEEKAERGEIAFALVGEKSFAIPGGLEEQKKVSKVLDEMSVEGKIELIYYGLKEDAREDMAKGEIDYVFIRKAPTKEEVMELVKRGEVYSPKTTRHVLPFNPDKIDVKLEELF 5x0k A 1.65 BS01 AMP A 1 F40 S43 I49 F50 W51 K52 G70 H72 R73 F38 S41 I47 F48 W49 K50 G68 H70 R71 2.7.1.226 0005524,0016301,0016310,0019344 Q5JD03 28358477 301 VEKVPKYDIPTKKVDYVFIELDKMKPHQQLVQKELEAFIESVTGSGIFWKPMLLAKVPGEDMYLIVDGHHRWAGLQKLGAKRAPSVILDYFSDDVKVYTWYPAFKGDLNEVVERLKKEGLEVIEDPEAEEKAERGEIAFALVGEKSFAIPGGLEEQKKVSKVLDEMSVEGKIELIYYGLKEDAREDMAKGEIDYVFIRKAPTKEEVMELVKRGEVYSPKTTRHVLPFNPDKIDVKLEELF 5x8f A 1.763 BS02 AMP A 1 T152 G265 P266 S285 Y286 G287 M288 T289 D367 N393 T150 G263 P264 S283 Y284 G285 M286 T287 D365 N391 T152 S172 H196 T289 E290 I388 N393 K471 T150 S170 H194 T287 E288 I386 N391 K469 6.2.1.26 0005524,0008756,0009234,0016405,0016874 P23971 28559280 502 TEQPNWLMQRAQLTPERIALIYEDQTVTFAELFAASKRMAEQLAAHSVRKGDTAAILLQNRAEMVYAVHACFLLGVKAVLLNTKLSTHERLFQLEDSGSGFLLTDSSFEKKEYEHIVQTIDVDELMKEAAEEIEIEAYMQMDATATLMYTSGTTGKPKGVQQTFGNHYFSAVSSALNLGITEQDRWLIALPLFHISGLSALFKSVIYGMTVVLHQRFSVSDVLHSINRHEVTMISAVQTMLASLLEETNRCPESIRCILLGGGPAPLPLLEECREKGFPVFQSYGMTETCSQIVTLSPEFSMEKLGSAGKPLFSCEIKIERDGQVCEPYEHGEIMVKGPNVMKSYFNRESANEASFQNGWLKTGDLGYLDNEGFLYVLDRRSDLIISGGENIYPAEVESVLLSHPAVAEAGVSGAEDKKWGKVPHAYLVLHKPVSAGELTDYCKERLAKYKRPKKFFVLDRLPRNASNKLLRNQLKDARKGEL 5x8f C 1.763 BS02 AMP C 1 T152 G265 P266 S285 Y286 G287 M288 T289 D367 I388 N393 T150 G263 P264 S283 Y284 G285 M286 T287 D365 I386 N391 T152 S172 H196 T289 E290 I388 N393 K471 T150 S170 H194 T287 E288 I386 N391 K469 6.2.1.26 0005524,0008756,0009234,0016405,0016874 P23971 28559280 502 TEQPNWLMQRAQLTPERIALIYEDQTVTFAELFAASKRMAEQLAAHSVRKGDTAAILLQNRAEMVYAVHACFLLGVKAVLLNTKLSTHERLFQLEDSGSGFLLTDSSFEKKEYEHIVQTIDVDELMKEAAEEIEIEAYMQMDATATLMYTSGTTGKPKGVQQTFGNHYFSAVSSALNLGITEQDRWLIALPLFHISGLSALFKSVIYGMTVVLHQRFSVSDVLHSINRHEVTMISAVQTMLASLLEETNRCPESIRCILLGGGPAPLPLLEECREKGFPVFQSYGMTETCSQIVTLSPEFSMEKLGSAGKPLFSCEIKIERDGQVCEPYEHGEIMVKGPNVMKSYFNRESANEASFQNGWLKTGDLGYLDNEGFLYVLDRRSDLIISGGENIYPAEVESVLLSHPAVAEAGVSGAEDKKWGKVPHAYLVLHKPVSAGELTDYCKERLAKYKRPKKFFVLDRLPRNASNKLLRNQLKDARKGELL 5yfu A 2.35 BS02 AMP A 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 403 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfu A 2.35 BS03 AMP C 1 N209 A211 L250 V251 V283 N207 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 403 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfu B 2.35 BS01 AMP A 1 N209 L250 V251 V283 N207 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 403 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfu B 2.35 BS03 AMP B 1 R124 R229 W231 D290 R122 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 403 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfu C 2.35 BS01 AMP B 1 N209 A211 L250 V251 V283 N207 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 403 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfu C 2.35 BS03 AMP C 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 403 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfv A 2.75 BS02 AMP A 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfv A 2.75 BS03 AMP C 1 N209 A211 L250 V251 V283 N207 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfv B 2.75 BS01 AMP A 1 N209 A211 L250 V251 V283 N207 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfv B 2.75 BS03 AMP B 1 R124 R229 W231 D290 R122 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfv C 2.75 BS01 AMP B 1 A211 L250 V251 V283 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfv C 2.75 BS03 AMP C 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfw A 2.35 BS02 AMP A 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfw A 2.35 BS03 AMP C 1 T207 L250 V251 V283 T205 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfw B 2.35 BS01 AMP A 1 T207 L250 V251 V283 T205 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfw B 2.35 BS03 AMP B 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfw C 2.35 BS01 AMP B 1 N209 V251 V283 N207 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfw C 2.35 BS03 AMP C 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfx A 2.7 BS02 AMP A 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWE 5yg8 A 2.8 BS02 AMP A 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 403 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg8 A 2.8 BS03 AMP C 1 A211 L250 V251 V283 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg8 B 2.8 BS01 AMP A 1 T207 N209 L250 V251 V283 T205 N207 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 403 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg8 B 2.8 BS03 AMP B 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg8 C 2.8 BS01 AMP B 1 N209 A211 L250 V251 V283 N207 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg8 C 2.8 BS03 AMP C 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg9 A 2.8 BS02 AMP A 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg9 A 2.8 BS03 AMP C 1 A211 L250 V251 V283 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg9 B 2.8 BS01 AMP A 1 N209 A211 L250 V251 V283 N207 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg9 B 2.8 BS03 AMP B 1 R124 R229 W231 D290 R122 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg9 C 2.8 BS01 AMP B 1 N209 A211 L250 V251 V283 N207 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg9 C 2.8 BS03 AMP C 1 W231 D290 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yga A 2.45 BS02 AMP A 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 403 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yga A 2.45 BS03 AMP C 1 N209 A211 L250 V251 V283 N207 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yga B 2.45 BS01 AMP A 1 N209 A211 L250 V251 V283 N207 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 403 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yga B 2.45 BS03 AMP B 1 R124 R229 W231 D290 R122 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yga C 2.45 BS01 AMP B 1 N209 A211 L250 V251 V283 N207 A209 L248 V249 V281 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yga C 2.45 BS03 AMP C 1 R229 W231 D290 R227 W229 D288 5.3.1.29 0016853,0019323,0019509,0043917,0044237,0044249,0046523 O57947 29382938 402 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yz2 A 1.75 BS01 AMP A 1 I80 H100 T180 D183 I18 H38 T118 D121 ? Kd=11.3uM -logKd/Ki=4.95, Kd=11.3uM P0AE78 29453981 301 ELALQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 5yz2 B 1.75 BS01 AMP B 1 I74 M79 I80 H100 S101 T180 D183 I12 M17 I18 H38 S39 T118 D121 ? Kd=11.3uM -logKd/Ki=4.95, Kd=11.3uM P0AE78 29453981 301 ELALQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEKGQFL 5zbk A 2.3 BS01 AMP A 1 A12 E74 M89 R92 K93 G109 G111 T112 A11 E73 M88 R91 K92 G108 G110 T111 3.2.2.4,3.2.2.n1 0005829,0008714,0009691,0016787,0016799,0102682 P48636 29901273 304 TLRSVCVFCGASPGASPVYQEAAVALGRHLAERGLTLVYGGGAVGLMGTVADAALAAGGEVIGIIPQSLQEAEIGHKGLTRLEVVDGMHARKARMAELADAFIALPGGLGTLEALFEVWTWGQLGYHAKPLGLLEVNGFYDPLLTFLDHLVDERFVRAEHRGMLQRGASPEALLDALAAWTP 5zbl C 2.3 BS01 AMP C 1 G18 S19 R99 K100 G116 G118 T119 E121 E122 G10 S11 R85 K86 G102 G104 T105 E107 E108 3.2.2.n1 0000166,0005829,0009691,0016787,0016799,0102682 Q8NN34 29901273 301 TLQRVTVFTGSALGSSSLYTQAAQTLAKTAVDRGIDLVYGGGKVGLMGIVADAFLESGGEAFGVITESGHEKLTELEIVPDMHIRKRRMAELGDGFIAMPGGAGTLEELFEVWTWQQLGIHQKPVALYDVDGFWQPLLEMLEQMTQRGFIKRDFFECLIVESDPHALLKAMQTWTP 5zbl D 2.3 BS01 AMP D 1 S19 M55 R99 K100 G116 G118 T119 E121 E122 S11 M47 R90 K91 G107 G109 T110 E112 E113 3.2.2.n1 0000166,0005829,0009691,0016787,0016799,0102682 Q8NN34 29901273 301 TLQRVTVFTGSALGSSSLYTQAAQTLAKTAVDRGIDLVYGGGKVGLMGIVADAFLESGGEAFGVITESLMKGLGHEKLTELEIVPDMHIRKRRMAELGDGFIAMPGGAGTLEELFEVWTWQQLGIHQKPVALYDVDGFWQPLLEMLEQMTQRGFIKRDFFECLIVESDPHALLKAMQTWTP 5zq4 A 2.217 BS01 AMP A 1 Y343 W390 N400 H403 M404 Y420 Q424 Y122 W169 N179 H182 M183 Y199 Q203 ? Q6BBR6 29731171 601 SVPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTLRTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQSRDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEYYFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIGQDGNPIREESSGELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCENDVDFCLGQLQTAHHQT 5zq4 B 2.217 BS01 AMP B 1 Y343 W390 N400 H403 M404 Q424 Y122 W169 N179 H182 M183 Q203 ? Q6BBR6 29731171 601 SVPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTLRTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQSRDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEYYFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIGQDGNPIREESSGELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCENDVDFCLGQLQTAHHQT 5zq7 A 2.847 BS02 AMP A 1 W390 N400 H403 M404 Q424 W169 N179 H182 M183 Q203 ? 0106274 Q6BBR6 29731171 1102 SVPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTLRTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQSRDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEYYFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIGQDGNPIREEGELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCENDVDFCLGQLQTAHHQTKITPIKRAFQSSSEKARRQPNMDEIAAARIVQQIMANPDCIHDDHVFLNGQKLEEKFFRDLLAKCDMAIVGSLLNDTDIRNIDTLMQHERNTEFHSTDAKAKPVKLGETWEKTIRSGGGVTQIKHDLIFLMQNDAWYHTRVNAIAQNRDKDSTFKEVLITALMTPLTNKSLMDTSRSPAPKTLFRGLDLSEEFKNKLINQAETIIANTTEHLFTDLSTEAFKQIKLNDFSQVSARTCASTSTNIEVPRTIFGSNTIFEILDPDGLLHPKQVGTHVSGSESEYSIYLPEDVALVPIKVSFDGKTGKGKDRHIFTLVAVKSPDFTPRHESGYAVGPLLKMQTPKLEEIQRLVEQAREEPDLERVFNLQSRVARQAKFSTESGYKTFLNEKVAPVLEQSLNGLLDNNVTILGKVLSAFPSDGQWSAFNSVEARQMKIQMDAIKQMVEKKAVLEGQILPALAQCQNALEKQNIAGALQALRNIPSL 5zq7 C 2.847 BS02 AMP C 1 W390 N400 M404 Q424 W168 N178 M182 Q202 ? 0106274 Q6BBR6 29731171 1102 VPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTLRTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQSRDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEYYFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIGQDGNPIRELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCENDVDFCLGQLQTAHHQTKITPIKRAFQSSSEKARRQPNMDEIAAARIVQQIMANPDCIHDDHVFLNGQKLEEKFFRDLLAKCDMAIVGSLLNDTDIRNIDTLMQHERNTEFHSTDAKAKPVKLGETWEKTIRSGGGVTQIKHDLIFLMQNDAWYHTRVNAIAQNRDKDSTFKEVLITALMTPLTNKSLMDTSRSPAPKTLFRGLDLSEEFKNKLINQAETIIANTTEHLFTDLSTEAFKQIKLNDFSQVSARTCASTSTNIEVPRTIFGSNTIFEILDPDGLLHPKQVGTHVSGSESEYSIYLPEDVALVPIKVSFDGKTGKGKDRHIFTLVAVKSPDFTPRHESGYAVGPLLKMQTPKLEEIQRLVEQAREEPDLERVFNLQSRVARQAKFSTESGYKTFLNEKVAPVLEQSLNGLLDNNVTILGKVLSAFPSDGQWSAFNSVEARQMKIQMDAIKQMVEKKAVLEGQILPALAQCQNALEKQNIAGALQALRNIPSL 5zu7 A 1.705 BS01 AMP A 1 D20 A21 G46 I47 L124 A127 G128 N154 D21 A22 G47 I48 L125 A128 G129 N155 3.4.19.12 T2B9G2 201 MPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTI 5zwk A 2.104 BS02 AMP A 1 V17 E20 G21 A24 G26 T27 G28 E29 L30 K112 Y113 V160 M177 V9 E12 G13 A16 G18 T19 G20 E21 L22 K96 Y97 V144 M161 3.1.3.11 0000166,0005975,0006094,0016787,0016791,0042132,0042578,0046872 Q2TU34 402 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 5zwk B 2.104 BS02 AMP B 1 V17 E20 G21 T27 E29 L30 K112 Y113 M177 V9 E12 G13 T19 E21 L22 K96 Y97 M161 3.1.3.11 0000166,0005975,0006094,0016787,0016791,0042132,0042578,0046872 Q2TU34 402 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 5zwk C 2.104 BS02 AMP C 1 V17 E20 G21 A24 G26 T27 E29 L30 K112 Y113 V160 M177 V9 E12 G13 A16 G18 T19 E21 L22 K96 Y97 V144 M161 3.1.3.11 0000166,0005975,0006094,0016787,0016791,0042132,0042578,0046872 Q2TU34 402 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 5zwk D 2.104 BS02 AMP D 1 V17 E20 G21 A24 T27 E29 L30 K112 Y113 M177 V9 E12 G13 A16 T19 E21 L22 K96 Y97 M161 3.1.3.11 0000166,0005975,0006094,0016787,0016791,0042132,0042578,0046872 Q2TU34 402 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 6aic A 1.8 BS01 AMP A 1 F22 E24 T26 Q29 G49 G51 K52 T53 F20 E22 T24 Q27 G47 G49 K50 T51 3.6.4.13 0003676,0003724,0005524 Q6GEZ3 30387775 301 NFKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILGQAQTGTGKTGAFGIPLIEKVVGKQGVQSLILAPTRELAMQVAEQLREFSRGQGVQVVTVFGGMPIERQIKALKKGPQIVVGTPGRVIDHLNRRTLKTDGIHTLILDEADEMMNMGFIDDMRFIMDKIPAVQRQTMLFSATMPKAIQALVQQFMKSPKIIK 6ang A 2.45 BS01 AMP A 1 K103 V104 P105 R117 E137 V141 K99 V100 P101 R113 E133 V137 0006797,0008976,0016776 401 FSKLSKYVETLRVKPKQSIDLKKDFDTDYDHKMLTKEEGEELLNLGISKLSEIQEKLYASGTKSVLIVFQAMDAAGKDGTVKHIMTGLNPQGVKVTSFKVPSKIELSHDYLWRHYVALPATGEIGIFNRSHYENVLVTRVHPEYLLSEQTSGVTAIEQVNQKFWDKRFQQINNFEQHISENGTIVLKFFLHVSKKEQKKRFIERIELDTKNWKFSTGDLKERAHWKDYRNAYEDMLANTSTKQAPWFVIPADDKWFTRLLIAEIICTELEKLNLTFPTVSLEQKAELEKAKAELVAE 6avh A 3.011 BS01 AMP A 1 I300 T302 F325 Y326 G327 S329 Y348 D408 F424 K556 I278 T280 F303 Y304 G305 S307 Y326 D372 F388 K517 6.3.2.- 0005524,0005829,0010249,0016874,0070406 Q8GZ29 29462792 600 DPTNQKACLSLLEDLTTNVKQIQDSVLEAILSRNAQTEYLRGFLNGQVDKQNFKKNVPVVTYEDIRSYIDRIANGEPSDLICDRPISVLLTPKLIPLTTEDLEQRISFSSLYAPLLYKHIDGLSEGKSLIFYFVTRESKTANGLMVRTMVTSFLKSDSLQVSPHAITTCADTTQSMYCQLLCGLLERDNVARLGAPFASSFLKVIKFLEDHWPELCSNIRTGRLSDWITDATCTSGIGKFLTAPNPELASLIEQECSKTSWEAILKRLWPKAKCIESIITGTMAQYIPLLEFYSGGLPLTSSFYGSSECFMGVNFNPLCKPSDVSYTIIPCMGYFEFLEVPVVVDLVDVKIGHDYEPVVTTFSGLYRYRVGDVLRATGFYNNAPHFCFVGRQKVVLSIDMDKTYEDDLLKAVTNAKLLLEPHDLMLMDFTSRVDSSSFPGHYVIYWELGSKVKFEPNRDVMEECCFTVEESLDAVYRKGRKNDKNIGPLEIKVVKPGAFDELMNFFLSRGSSVSQYKTPRSVTNEEALKILEANVISEFLSRKIPSW 6avh B 3.011 BS01 AMP B 1 I300 T302 G327 S328 S329 Y348 D408 F424 R427 Q554 I274 T276 G301 S302 S303 Y322 D366 F382 R385 Q509 6.3.2.- 0005524,0005829,0010249,0016874,0070406 Q8GZ29 29462792 600 PTNQKACLSLLEDLTTNVKQIQDSVLEAILSRNAQTEYLRGFLNGQVDKQNFKKNVPVVTYEDIRSYIDRIANGEPSDLICDRPISVLLTSKLIPLTTEDLEQRISFSSLYAPLLYKHIDGLSEGKSLIFYFVTRESKTANGLMVRTMVTSFLKSDSLQVSPHAITTCADTTQSMYCQLLCGLLERDNVARLGAPFASSFLKVIKFLEDHWPELCSNIRTSDWITDATCTSGIGKFLTAPNPELASLIEQECSKTSWEAILKRLWPKAKCIESIITGTMAQYIPLLEFYSGGLPLTSSFYGSSECFMGVNFNPLCKPSDVSYTIIPCMGYFEFLEVVVDLVDVKIGHDYEPVVTTFSGLYRYRVGDVLRATGFYNNAPHFCFVGRQKVVLSIDMDKTYEDDLLKAVTNAKLLLEPHDLMLMDFTSRVDSSSFPGHYVIYWELGSKVKFEPNRDVMEECCFTVEESLDAVYRKGRKNDKNIGPLEIKVVKPGAFDELMNFFLSRGSSVSQYKTPRSVTNEEALKILEANVISEFLSRKIPSW 6avh C 3.011 BS01 AMP C 1 S98 I300 T302 F325 Y326 G327 S328 Y348 D408 F424 K556 S96 I289 T291 F314 Y315 G316 S317 Y337 D382 F398 K521 6.3.2.- 0005524,0005829,0010249,0016874,0070406 Q8GZ29 29462792 600 PKFDPTNQKACLSLLEDLTTNVKQIQDSVLEAILSRNAQTEYLRGFLNGQVDKQNFKKNVPVVTYEDIRSYIDRIANGEPSDLICDRPISVLLTSSGTSGGVPKLIPLTTEDLEQRISFSSLYAPLLYKHIDGLSEGKSLIFYFVTRESKTANGLMVRTMVTSFLKSDSLQVSPHAITTCADTTQSMYCQLLCGLLERDNVARLGAPFASSFLKVIKFLEDHWPELCSNIRTGRLSDWITDATCTSGIGKFLTAPNPELASLIEQECSKTSWEAILKRLWPKAKCIESIITGTMAQYIPLLEFYSGGLPLTSSFYGSSECFMGVNFNPLCKPSDVSYTIIPCMGYFEFLEVVVVDLVDVKIGHDYEPVVTTFSGLYRYRVGDVLRATGFYNNAPHFCFVGRQKVVLSIDMDKTYEDDLLKAVTNAKLLLEPHDLMLMDFTSRVDSSSFPGHYVIYWELGPNRDVMEECCFTVEESLDAVYRKGRKNDKNIGPLEIKVVKPGAFDELMNFFLSRGSSVSQYKTPRSVTNEEALKILEANVISEFLSRKIPSWE 6avh D 3.011 BS01 AMP D 1 S97 S98 I300 T302 F325 G327 S328 S329 Y348 D408 F424 R427 K556 S95 S96 I281 T283 F306 G308 S309 S310 Y329 D375 F391 R394 K517 6.3.2.- 0005524,0005829,0010249,0016874,0070406 Q8GZ29 29462792 600 PKFDPTNQKACLSLLEDLTTNVKQIQDSVLEAILSRNAQTEYLRGFLNGQVDKQNFKKNVPVVTYEDIRSYIDRIANGEPSDLICDRPISVLLTSSGTVPKLIPLTTEDLEQRISFSSLYAPLLYKHIDGLSEGKSLIFYFVTRESKTANGLMVRTMVTSFLKSDSLQVSPHAITTCADTTQSMYCQLLCGLLERDNVARLGAPFASSFLKVIKFLEDHWPELCSNIRTGRLSDWITDATCTSGIGKFLTAPNPELASLIEQECEAILKRLWPKAKCIESIITGTMAQYIPLLEFYSGGLPLTSSFYGSSECFMGVNFNPLCKPSDVSYTIIPCMGYFEFLEVPVVVDLVDVKIGHDYEPVVTTFSGLYRYRVGDVLRATGFYNNAPHFCFVGRQKVVLSIDMDKTYEDDLLKAVTNAKLLLEPHDLMLMDFTSRVDSSSFPGHYVIYWELGSFEPNRDVMEECCFTVEESLDAVYRKGRKNDKNIGPLEIKVVKPGAFDELMNFFLSRGSSVSQYKTPRSVTNEEALKILEANVISEFLSRKIPSWEL 6awa A 1.83 BS01 AMP A 1 I187 E211 A212 L213 V245 V277 I187 E211 A212 L213 V245 V277 L45 C49 C54 S57 V191 E195 F449 H451 E456 N474 R475 L45 C49 C54 S57 V191 E195 F449 H451 E456 N474 R475 1.8.1.4 0000166,0004148,0005737,0016491,0016668,0050660 Q88FB1 501 MTQKFDVVVIGAGPGGYVAAIKAAQLGLKTACIEKYTDAEGKLALGGTCLNVGCIPSKALLDSSWKYKEAKESFNVHGISTGEVKMDVAAMVGRKAGIVKNLTGGVATLFKANGVTSIQGHGKLLAGKKVEVTKADGTTEVIEAENVILASGSRPIDIPPAPVDQNVIVDSTGALEFQAVPKRLGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLTKQGLDIKLGARVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVAVGRRPVTTDLLASDSGVTIDERGYIFVDDYCATSVPGVYAIGDVVRGMMLAHKASEEGIMVVERIKGHKAQMNYDLIPSVIYTHPEIAWVGKTEQALKAEGVEVNVGTFPFAASGRAMAANDTGGFVKVIADAKTDRVLGVHVIGPSAAELVQQGAIAMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGGAIHVANR 6awa B 1.83 BS01 AMP B 1 I187 E211 A212 L213 V245 V277 I187 E211 A212 L213 V245 V277 L45 C49 C54 S57 V191 E195 F449 H451 E456 N474 R475 L45 C49 C54 S57 V191 E195 F449 H451 E456 N474 R475 1.8.1.4 0000166,0004148,0005737,0016491,0016668,0050660 Q88FB1 501 MTQKFDVVVIGAGPGGYVAAIKAAQLGLKTACIEKYTDAEGKLALGGTCLNVGCIPSKALLDSSWKYKEAKESFNVHGISTGEVKMDVAAMVGRKAGIVKNLTGGVATLFKANGVTSIQGHGKLLAGKKVEVTKADGTTEVIEAENVILASGSRPIDIPPAPVDQNVIVDSTGALEFQAVPKRLGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLTKQGLDIKLGARVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVAVGRRPVTTDLLASDSGVTIDERGYIFVDDYCATSVPGVYAIGDVVRGMMLAHKASEEGIMVVERIKGHKAQMNYDLIPSVIYTHPEIAWVGKTEQALKAEGVEVNVGTFPFAASGRAMAANDTGGFVKVIADAKTDRVLGVHVIGPSAAELVQQGAIAMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGGAIHVANR 6b1u E 2.77 BS01 AMP E 1 R70 K170 I240 S242 F244 D245 R269 V276 L277 V297 H298 R299 R45 K144 I214 S216 F218 D219 R243 V250 L251 V271 H272 R273 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 29657085 401 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 6b1u E 2.77 BS02 AMP E 2 H151 T200 I204 A205 V225 S226 H298 I312 S314 S316 D317 H125 T174 I178 A179 V199 S200 H272 I286 S288 S290 D291 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 29657085 402 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 6b1u F 2.77 BS01 AMP F 1 K170 I240 S242 F244 D245 R269 V276 L277 V297 H298 R299 K145 I215 S217 F219 D220 R244 V251 L252 V272 H273 R274 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 29657085 401 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 6b1u F 2.77 BS02 AMP F 2 H151 T200 I204 A205 V225 S226 H298 I312 S314 S316 D317 H126 T175 I179 A180 V200 S201 H273 I287 S289 S291 D292 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 29657085 402 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 6b2e C 3.8 BS01 AMP C 1 R70 I240 S242 F244 D245 F273 V276 L277 V297 H298 R299 R46 I211 S213 F215 D216 F244 V247 L248 V268 H269 R270 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 29657085 400 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 6b2e C 3.8 BS02 AMP C 2 H151 T200 A205 V225 S226 A227 S314 S316 D317 H122 T171 A176 V196 S197 A198 S285 S287 D288 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 29657085 401 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 6bkf A 3.25 BS03 AMP A 1 K273 L274 R278 F367 M430 K432 K449 K451 K252 L253 R257 F331 M394 K396 K413 K415 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0051103,0071897 P49917 29980672 701 TVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSALEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISITLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTDQFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNEAIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKRGGMMSHFLCAVAEKPPKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILCGTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLEQLR 6bkg A 2.402 BS04 AMP D 1 E271 K273 L274 R278 E331 F367 M430 K432 K449 E259 K261 L262 R266 E319 F351 M414 K416 K433 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0051103,0071897 P49917 29980672 101 SQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGDAGDFAMIAYFVLKPRCQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSALEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISITLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTDQFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNEAIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMMSHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILCGTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLEQLRGKASGKLASKHLY 6blj A 2.1 BS01 AMP A 1 R306 E308 R321 V322 F325 L399 S401 A439 R442 R309 E311 R324 V325 F328 L402 S404 A435 R438 0000166,0004812,0004828,0005524,0006418,0006434 500 HHHMLDINLFREYKGGNPEIIRESQRRRFADVTLVDKVIELDEVWRATIGKLNHIKSFTGIISKEVGNRMKNKVPLGDDLELPKEVTDDVYALFTKEALEQGSLAKLNTNQLKKLSTYITEVHIKNSEEEVKQKEKERDDVLLQIGNIVHETVVVSDNEDNNGIVRMVGNPRPKVDPETGYKCLKHIDIMRKLGGLATEEGTQVGGGRGYFLLGDLVRMNLALQNYAIDFLAKKGYMPIYTPFFMTKEQMKKVAQLSQFDEELYTVTGEGEDKYLIATSEQPIAAFHLEKRFDESELPIKYCGMSTCFRKEVGAHGKDTLGIFRVHQFEKIEQFVVTSPKDNKSWEMFDEMIGNSEAFYQSLGIPYRVVNIVSGALNNAAAKKFDLEAWFPGADEGNEYRELVSCSNCTDYQTRRLEVKYGEVEFCHMLNSTLTATSRTLCCIVENYQTPEGVNVPEVLQPYMGGTKFIKFKN 6blj B 2.1 BS01 AMP B 1 R306 E308 R321 V322 F325 E398 L399 S401 A439 R442 R264 E266 R279 V280 F283 E356 L357 S359 A397 R400 0000166,0004812,0004828,0005524,0006418,0006434 500 HHHMLDINLFREYKGGNPEIIRESQRRRFADVTLVDKVIELDEVWRATIGKLNHIKSFTGIISKEQLKKLSTYITEVHIKNSEEEVKQKEKERDDVLLQIGNIVHETVVVSDNEDNNGIVRMVGNPRPKVDPETGYKCLKHIDIMRKLGGLATEEGTQVGGGRGYFLLGDLVRMNLALQNYAIDFLAKKGYMPIYTPFFMTKEQMKKVAQLSQFDEELYTVTGEGEDKYLIATSEQPIAAFHLEKRFDESELPIKYCGMSTCFRKEVGAHGKDTLGIFRVHQFEKIEQFVVTSPKDNKSWEMFDEMIGNSEAFYQSLGIPYRVVNIVSGALNNAAAKKFDLEAWFPGADEGNEYRELVSCSNCTDYQTRRLEVKYGKSKKQGSEVEFCHMLNSTLTATSRTLCCIVENYQTPEGVNVPEVLQPYMGGTKFIKFKN 6blj C 2.1 BS01 AMP C 1 R306 E308 R321 V322 F325 E398 L399 S401 A439 R442 R264 E266 R279 V280 F283 E356 L357 S359 A393 R396 0000166,0004812,0004828,0005524,0006418,0006434 500 HHHMLDINLFREYKGGNPEIIRESQRRRFADVTLVDKVIELDEVWRATIGKLNHIKSFTGIISKEQLKKLSTYITEVHIKNSEEEVKQKEKERDDVLLQIGNIVHETVVVSDNEDNNGIVRMVGNPRPKVDPETGYKCLKHIDIMRKLGGLATEEGTQVGGGRGYFLLGDLVRMNLALQNYAIDFLAKKGYMPIYTPFFMTKEQMKKVAQLSQFDEELYTVTGEGEDKYLIATSEQPIAAFHLEKRFDESELPIKYCGMSTCFRKEVGAHGKDTLGIFRVHQFEKIEQFVVTSPKDNKSWEMFDEMIGNSEAFYQSLGIPYRVVNIVSGALNNAAAKKFDLEAWFPGADEGNEYRELVSCSNCTDYQTRRLEVKYGQGSEVEFCHMLNSTLTATSRTLCCIVENYQTPEGVNVPEVLQPYMGGTKFIKFKN 6c9f C 2.924 BS01 AMP C 1 M84 T86 T88 D89 L128 V129 I149 H150 R151 M60 T62 T64 D65 L104 V105 I125 H126 R127 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 30478170 1101 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 6c9f C 2.924 BS02 AMP C 2 R69 I239 S241 F243 D244 R268 V275 L276 V296 H297 R298 R45 I215 S217 F219 D220 R244 V251 L252 V272 H273 R274 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 30478170 1102 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 6c9f C 2.924 BS03 AMP C 3 H150 T199 I203 A204 V224 S225 R298 I311 S313 S315 D316 H126 T175 I179 A180 V200 S201 R274 I287 S289 S291 D292 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 30478170 1103 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 6c9g C 2.7 BS01 AMP C 1 M84 T86 T88 D89 L128 V129 I149 H150 R151 M60 T62 T64 D65 L104 V105 I125 H126 R127 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 30478170 1101 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 6c9g C 2.7 BS02 AMP C 2 I239 F243 D244 R268 V275 L276 V296 H297 R298 I215 F219 D220 R244 V251 L252 V272 H273 R274 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 30478170 1102 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 6c9g C 2.7 BS03 AMP C 3 H150 T199 I203 A204 V224 S225 H297 I311 S315 D316 H126 T175 I179 A180 V200 S201 H273 I287 S291 D292 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 30478170 1103 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 6c9h C 2.65 BS01 AMP C 1 M84 T86 T88 D89 L128 V129 H150 R151 M59 T61 T63 D64 L103 V104 H125 R126 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 30478170 1101 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 6c9h C 2.65 BS02 AMP C 2 R69 I239 S241 F243 D244 R268 V275 L276 V296 H297 R298 R44 I214 S216 F218 D219 R243 V250 L251 V271 H272 R273 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 30478170 1102 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 6c9h C 2.65 BS03 AMP C 3 H150 T199 A204 V224 S225 H297 S313 D316 H125 T174 A179 V199 S200 H272 S288 D291 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 30478170 1103 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 6c9j C 3.05 BS01 AMP C 1 H150 T199 I203 A204 V224 S225 A226 I311 S313 S315 D316 H126 T175 I179 A180 V200 S201 A202 I287 S289 S291 D292 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 30478170 401 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 6cvo A 2.4 BS03 AMP A 1 L171 D193 K194 Y195 L203 H251 P254 S255 M256 H260 H262 L7 D29 K30 Y31 L39 H87 P90 S91 M92 H96 H98 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 29934293 401 GHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKH 6cvo B 2.4 BS03 AMP B 1 L171 D193 K194 Y195 L203 H251 P254 S255 M256 H260 H262 L9 D31 K32 Y33 L41 H89 P92 S93 M94 H98 H100 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 29934293 401 HMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 6cvp A 1.999 BS03 AMP A 1 L171 S174 D193 K194 Y195 L203 H251 P254 S255 M256 H260 H262 L7 S10 D29 K30 Y31 L39 H87 P90 S91 M92 H96 H98 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 29934293 401 GHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKAHYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 6cvp B 1.999 BS03 AMP B 1 L171 D193 K194 Y195 L203 H251 P254 S255 M256 H260 H262 L10 D32 K33 Y34 L42 H90 P93 S94 M95 H99 H101 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 29934293 401 SHMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKAHYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 6cvq A 1.65 BS03 AMP A 1 L171 S174 D193 K194 Y195 H251 P254 S255 M256 H260 H262 L11 S14 D33 K34 Y35 H91 P94 S95 M96 H100 H102 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 29934293 401 GSHMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYQWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 6cvq B 1.65 BS03 AMP B 1 L171 D193 K194 Y195 L203 H251 S255 M256 H260 H262 L11 D33 K34 Y35 L43 H91 S95 M96 H100 H102 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 29934293 401 GSHMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYQWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 6cvr A 1.88 BS03 AMP A 1 L171 S174 D193 K194 Y195 H251 P254 S255 M256 H260 H262 L11 S14 D33 K34 Y35 H91 P94 S95 M96 H100 H102 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 29934293 401 GSHMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSNKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 6cvr B 1.88 BS03 AMP B 1 L171 D193 K194 Y195 L203 H251 S255 H260 H262 L9 D31 K32 Y33 L41 H89 S93 H98 H100 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 29934293 401 HMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSNKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 6cvs A 2.11 BS03 AMP A 1 L171 S174 D193 K194 Y195 H251 S255 M256 H260 H262 L11 S14 D33 K34 Y35 H91 S95 M96 H100 H102 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 29934293 401 GSHMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRMGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 6cvs B 2.11 BS03 AMP B 1 G170 S174 I191 D193 K194 L203 H251 S255 M256 H260 H262 G8 S12 I29 D31 K32 L41 H89 S93 M94 H98 H100 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 29934293 401 HMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRMGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 6cvt A 2.941 BS04 AMP A 1 L171 D193 K194 Y195 L203 H251 P254 S255 M256 H260 H262 L8 D30 K31 Y32 L40 H88 P91 S92 M93 H97 H99 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 29934293 402 MGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHGISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHW 6cvt B 2.941 BS04 AMP B 1 L171 S174 D193 K194 Y195 L203 H251 P254 S255 M256 H260 L9 S12 D31 K32 Y33 L41 H89 P92 S93 M94 H98 3.6.1.71,3.6.1.72 0003824 Q7Z2E3 29934293 402 HMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHGISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKH 6czm A 2.88 BS01 AMP A 1 D212 L213 S215 S216 G217 T218 T219 D177 L178 S180 S181 G182 T183 T184 2.4.2.17 0000105,0000166,0000287,0003879,0005737,0016757 G7JFL4 30072492 401 SRQEIRLGLPSKGRMSSDTLDLLKDCQLSVKQVNPRQYVAQIPQISNLEVWFQRPKDIVRKLLSGDLDLGIVGLDVLTEFGQGNEDLIVVHEALEYGDCRLSIAIPQYGIFENVNSLEELAKMPQWTEDKPLRVATGFTYLGPKFMKDNGIKHVAFSTADGALEAAPAMGIADAILDLVSSGTTLKENNLKEIEGGTVLESQAALVASRRSMIGRKGVLETTHEMLERLEAHLRAMGQFTVVANMRGSSAEEVAERVLSQPSLAGLQGPTVSPVFCKRDGKVSADYYAIVICVPKKALYKSIQQLRAIGGSGVLVSPLTYIFDEETPRWRQLLSKLGL 6czm B 2.88 BS01 AMP B 1 C134 D212 L213 S215 S216 G217 T218 T219 C91 D147 L148 S150 S151 G152 T153 T154 2.4.2.17 0000105,0000166,0000287,0003879,0005737,0016757 G7JFL4 30072492 401 EIRLGLPSKGRMSSDTLDLLKDCQLSVRQYVAQIPQISNLEVWFQRPKDIVRKLLSGDLDLGIVGLDVLTEFGQGNEDLIVVHEALEYGDCRLSIAIPQKMPQWTEDLRVATGFTYLGPKFMKDNGHVAFSTAALEAAPAMGIAILDLVSSGTTLKENNLKEIEGGTVLESQAALVASRRSMIGRKGVLETTHEMLERLEAHLRAMGQFTVVANMRGSSAEEVAERVLSQPSLAGLQGPTVSPVFCKRDGKVSADYYAIVICVPKKALYKSIQQLRAIGGSGVLVSPLTYIFDEETPRWRQLLSKLG 6czm C 2.88 BS02 AMP C 1 D212 L213 S215 S216 G217 T218 T219 D175 L176 S178 S179 G180 T181 T182 2.4.2.17 0000105,0000166,0000287,0003879,0005737,0016757 G7JFL4 30072492 401 NTVSRQEIRLGLPSKGRMSSDTLDLLKDCQLSVKQYVAQIPQISNLEVWFQRPKDIVRKLLSGDLDLGIVGLDVLTEFGQGNEDLIVVHEALEYGDCRLSIAIPQYGIFENVNSLEELAKMPQWTEDKPLRVATGFTYLGPKFMKDNGIKHVAFSTADGALEAAPAMGIADAILDLVSSGTTLKENNLKEIEGGTVLESQAALVASRRSMIGRKGVLETTHEMLERLEAHLRAMGQFTVVANMRGSSAEEVAERVLSQPSLAGLQGPTVSPVFCKRDGKVSADYYAIVICVPKKALYKSIQQLRAIGGSGVLVSPLTYIFDEETPRWRQLLSKLG 6czm D 2.88 BS01 AMP D 1 D212 L213 V214 S215 S216 G217 T218 T219 D174 L175 V176 S177 S178 G179 T180 T181 2.4.2.17 0000105,0000166,0000287,0003879,0005737,0016757 G7JFL4 30072492 401 SRQEIRLGLPSKGRMSSDTLDLLKDCQLSVKQVNPVAQIPQISNLEVWFQRPKDIVRKLLSGDLDLGIVGLDVLTEFGQGNEDLIVVHEALEYGDCRLSIAIPQYGIFENVNSLEELAKMPQWTEDKPLRVATGFTYLGPKFMKDNGIKHVAFSTADGALEAAPAMGIADAILDLVSSGTTLKENNLKEIEGGTVLESQAALVASRRSMIGRKGVLETTHEMLERLEAHLRAMGQFTVVANMRGSSAEEVAERVLSQPSLAGLQGPTVSPVFCKRDGKVSADYYAIVICVPKKALYKSIQQLRAIGGSGVLVSPLTYIFDEETPRWRQLLSKLGL 6czm E 2.88 BS01 AMP E 1 C134 D212 L213 S215 S216 G217 T219 C104 D182 L183 S185 S186 G187 T189 2.4.2.17 0000105,0000166,0000287,0003879,0005737,0016757 G7JFL4 30072492 401 NGNTVSRQEIRLGLPSKGRMSSDTLDLLKDCQLSVKQVNPRQYVAQIPQISNLEVWFQRPKDIVRKLLSGDLDLGIVGLDVLTEFGQGNEDLIVVHEALEYGDCRLSIAIPQYGIFENVNSLEELAKMPQWTEDKPLRVATGFTYLGPKFMKDNGIKHVAFSTADGALEAAPAMGIADAILDLVSSGTTLKENNLKEIEGGTVLESQAALVASRRSMIGRKGVLETTHEMLERLEAHLRAMGQFTVVANMRGSSAEEVAERVLSQPSLAGLQGPTVSPVFCKRDGKVSADYYAIVICVPKKALYKSIQQLRAIGGSGVLVSPLTYIFDEETPRWRQLLSKLG 6czm F 2.88 BS02 AMP F 1 S215 S216 G217 T219 S162 S163 G164 T166 2.4.2.17 0000105,0000166,0000287,0003879,0005737,0016757 G7JFL4 30072492 401 QEIRLGLPSKGRMSSDTLDLLKDCQLSVKQVNPRQYVAQIPQISNLEVWFQRPKDIVRKLLSLDLGIVGLDVLTEFGQGNEDLIVVHEALEYGDCRLSIAIPFENVNSLEELQWTEDKPLRVATGFTYLGPKFMKDNGIKHVAFSGALEAAPAMGAILDLVSSGTTLKENIEGGTVLESQAALVASRRSMIGRKGVLETTHEMLERLEAHLRAMGQFTVVANMRGSSAEEVAERVLSQPSLAGLQGPTVSPVFCKRDGKVSADYYAIVICVPKKALYKSIQQLRAIGGSGVLVSPLTYIFDEETPRWRQLLSKLG 6d31 A 1.2 BS01 AMP A 1 H120 S122 Y161 T162 N163 F170 Y202 S206 H208 S210 H43 S45 Y84 T85 N86 F93 Y125 S129 H131 S133 4.6.1.- 0004518,0034477 Q9BQ65 30215753 301 MGNWATHVYVPYEAKEEFLDLLDVLLPHAQTYVPRLVRMKVFHLSLSQSVVLRHHWILPFVQALKARMTSFHRFFFTANQVKIYTNQEKTRTFIGLEVTSGHAQFLDLVSEVDRVMEEFNLTTFYQDPSFHLSLAWCVGDARLQLEGQCLQELQAIVDGFEDAEVLLRVHTEQVRCKSGNKFFSMPLK 6dt1 A 2.75 BS04 AMP C 1 Q157 L158 K159 A160 R164 E217 W282 I347 K349 K365 K367 Q158 L159 K160 A161 R165 E218 W259 I324 K326 K342 K344 6.5.1.1 0003909,0003910,0005524,0006260,0006281,0006310,0016491,0016874,0046872 P00970 30169742 100 HMILKILNEIASIGSTKQKQAILEKNKDNELLKRVYRLTYSRGLQYYIKKWPKPGIATQSFGMLTLTDMLDFIEFTLATRKLTGNAAIEELTGYITDGKKDDVEVLRRVMMRDLECGASVSIANKVWPGLIPEQPQMLASSYDEKGINKNIKFPAFAQLKADGARCFAEVRGDELDDVRLLSRAGNEYLGLDLLKEELIKMTAEARQIHPEGVLIDGELVYHEQAEVAESRTASNGIANKSLKGTISEKEAQCMKFQVWDYVPLVEIYSLPAFRLKYDVRFSKLEQMTSGYDKVILIENQVVNNLDEAKVIYKKYIDQGLEGIILKNIDGLWENARSKNLYKFKEVIDVDLKIVGIYPHRKDPTKAGGFILESECGKIKVNAGSGLKDKAGVKSHELDRTRIMENQNYYIGKILECECNGWLKSDGRTDYVKLFLPIAIRLREDKTKANTFEDVFGDFHEVTGL 6dt1 E 2.75 BS04 AMP E 1 Q157 L158 K159 A160 R164 E217 W282 I347 K349 K365 K367 Q157 L158 K159 A160 R164 E217 W254 I319 K321 K337 K339 6.5.1.1 0003909,0003910,0005524,0006260,0006281,0006310,0016491,0016874,0046872 P00970 30169742 501 MILKILNEIASIGSTKQKQAILEKNKDNELLKRVYRLTYSRGLQYYIKKWPKPGIATQSFGMLTLTDMLDFIEFTLATRKLTGNAAIEELTGYITDGKKDDVEVLRRVMMRDLECGASVSIANKVWPGLIPEQPQMLASSYDEKGINKNIKFPAFAQLKADGARCFAEVRGDELDDVRLLSRAGNEYLGLDLLKEELIKMTAEARQIHPEGVLIDGELVYHVAESRTASNGIANKSLKGTISEKEAQCMKFQVWDYVPLVEIYSLPAFRLKYDVRFSKLEQMTSGYDKVILIENQVVNNLDEAKVIYKKYIDQGLEGIILKNIDGLWENARSKNLYKFKEVIDVDLKIVGIYPHRKDPTKAGGFILESECGKIKVNAGSGLKDKAGVKSHELDRTRIMENQNYYIGKILECECNGWLKSDGRTDYVKLFLPIAIRLREDKTKANTFEDVFGDFHEVTGL 6dzg D 1.87 BS01 AMP D 1 R149 F163 S220 M222 R137 F151 S208 M210 2.7.4.- 0006754,0006793,0008976,0016301,0016310,0042802 Q92SA6 401 GSRAVELEIDGRSRIFDIDDPDLPKWIDEEAFRSDDYPYKKKLDREEYEETLTKLQIELVKVQFWMQATGKRVMAVFEGRDAAGKGGAIHATTANMNPRSARVVALTKPTETERGQWYFQRYVATFPTAGEFVLFDRSWYNRAGVEPVMGFCTPDQYEQFLKEAPRFEEMIANEGIHLFKFWINIGREMQLKRFHDRRHDPLKIWKLSPMDIAALSKWDDYTGKRDRMLKETHTEHGPWAVIRGNDKRRSRINVIRHMLTKLDYDGKDEAAIGEVDEKILGSGPGFLR 6e4t C 3.4 BS01 AMP C 1 R69 I239 S241 F243 D244 R268 L276 V296 H297 R298 R44 I204 S206 F208 D209 R233 L235 V255 H256 R257 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 30036059 401 SVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 6e4t C 3.4 BS02 AMP C 2 H150 T199 I203 A204 V224 S225 I311 S313 S315 D316 H125 T164 I168 A169 V189 S190 I270 S272 S274 D275 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 30036059 402 SVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 6e4u C 3.27 BS01 AMP C 1 H150 T199 I203 A204 V224 S225 I311 S313 D316 H125 T166 I170 A171 V191 S192 I272 S274 D277 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 30036059 401 SVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 6e4u C 3.27 BS02 AMP C 2 R69 I239 S241 F243 R268 V275 L276 V296 H297 R298 R44 I206 S208 F210 R235 V236 L237 V257 H258 R259 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 30036059 402 SVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 6e4w C 3.35 BS01 AMP C 1 H150 T199 I203 A204 V224 S225 I311 S313 S315 D316 H123 T162 I166 A167 V187 S188 I267 S269 S271 D272 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 30036059 401 YTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 6e4w C 3.35 BS02 AMP C 2 R69 I239 S241 F243 D244 R268 L276 V296 H297 R298 R42 I202 S204 F206 D207 R231 L232 V252 H253 R254 ? 0004672,0004679,0005515,0005524,0005634,0005737,0005829,0006633,0010628,0016208,0019887,0019901,0031588,0031669,0032991,0043531,0044877,0051170 P80385 30036059 402 YTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 6e5y A 1.5 BS01 AMP A 1 A17 T42 A43 D194 A16 T41 A42 D193 D23 R107 D136 S192 D22 R106 D135 S191 6.3.4.5 0000050,0000053,0004055,0005524,0005737,0006526,0016874,0042803 Q7VTJ9 501 TTILPNLPTGQKVGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEPDYDEIPRRAMQYGAEAARLVDCRAQLVAEGIAALQAGAFHISTAGLTYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTFKGNDIERFYRYGLLTNPDLKIYKPWLDQTFIDELGGRAEMSEYMRQAGFDYKMSAEKAYSTDSNMLGATHEAKDLELLSAGIRIVQPIMGVAFWQDSVQIKAEEVTVRFEEGQPVALNGVEYADPVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLFIAYERLVTGIHNEDTIEQYRENGRKLGRLLYQGRWFDPQAIMLRETAQRWVARAITGEVTLELRRGNDYSLLNTESANLTYAPERLSMEKVENAPFTPADRIGQLTMRNLDIVDTREKLFTYVKTGLLAPSALPQIKD 6e8o A 1.7 BS01 AMP A 1 H237 G313 A314 K315 V335 F336 G337 M338 A339 D419 V431 K445 H234 G310 A311 K312 V332 F333 G334 M335 A336 D416 V428 K442 S193 S213 H237 A339 E340 N440 K445 K525 S190 S210 H234 A336 E337 N437 K442 K521 ? 0000166,0008668,0016874,0019290 Q47NR5 601 GCTPWPAEFAVRYREAGYWTGETFSDFVTDRTRRFADRLAVVGAGQRWTYAELGERSAVLATGLARLGIAAGDRVVVQLPNIPELFEVVFALFRLGALPVYALPAHRAHEITHLCTTAQAKALIIPDRHAGFDYRTMAAQLRHAGTAPEHVVVVGEPGGFTPLAELRADRPDPGVFTRPEASDAAFLQLSGGTTGLPKLIPRTHDDYLYSVRASAEICALGTDTVYLAALPAVHNFPMSSPGFLGTFHAGGTVVLAPNPSPDTAFSLIETERVTITAVVPPIALQWLDAVEHGSQSHRDLSSLRVLQVGGAKFAPEAARRVRPVLGCTLQQVFGMAEGLVNYTRLDDPDDIITTTQGRPISPDDEIRIVDEADRPVPDGEVGHLLTRGPYTIRGYYRAEEHNATAFTPDGFYRTGDLVRRTPTGHLVVEGRAKDQINRGGEKVSAEEVENHILAHPAVHDAAVVGMSDPYLGERVCAYVIARTEPPSRSELLRFLRERGLASYKIPDRVEFVDRFPVTGVKISRSELRRELARRLD 6e8o B 1.7 BS01 AMP B 1 H237 G313 A314 K315 V335 F336 G337 M338 A339 D419 V431 K445 H234 G310 A311 K312 V332 F333 G334 M335 A336 D416 V428 K442 S193 S213 H237 A339 E340 N440 K445 K525 S190 S210 H234 A336 E337 N437 K442 K519 ? 0000166,0008668,0016874,0019290 Q47NR5 601 GCTPWPAEFAVRYREAGYWTGETFSDFVTDRTRRFADRLAVVGAGQRWTYAELGERSAVLATGLARLGIAAGDRVVVQLPNIPELFEVVFALFRLGALPVYALPAHRAHEITHLCTTAQAKALIIPDRHAGFDYRTMAAQLRHAGTAPEHVVVVGEPGGFTPLAELRADRPDPGVFTRPEASDAAFLQLSGGTTGLPKLIPRTHDDYLYSVRASAEICALGTDTVYLAALPAVHNFPMSSPGFLGTFHAGGTVVLAPNPSPDTAFSLIETERVTITAVVPPIALQWLDAVEHGSQSHRDLSSLRVLQVGGAKFAPEAARRVRPVLGCTLQQVFGMAEGLVNYTRLDDPDDIITTTQGRPISPDDEIRIVDEADRPVPDGEVGHLLTRGPYTIRGYYRAEEHNATAFTPDGFYRTGDLVRRTPTGHLVVEGRAKDQINRGGEKVSAEEVENHILAHPAVHDAAVVGMSDPYLGERVCAYVIAPPSRSELLRFLRERGLASYKIPDRVEFVDRFPVTGVGKISRSELRRELARRLD 6eh2 A 1.76 BS02 AMP A 1 A70 Y122 V123 L173 D184 F327 A70 Y122 V123 L173 D184 F325 D166 K168 N171 D184 T201 D166 K168 N171 D184 T201 2.7.11.11 0000287,0001669,0001707,0001843,0004672,0004674,0004679,0004691,0004712,0005524,0005634,0005737,0005739,0005813,0005829,0005886,0005930,0005952,0006397,0006468,0006611,0007189,0007193,0010737,0016310,0016607,0018105,0019901,0019904,0030145,0031594,0031625,0032024,0034237,0034605,0036126,0044853,0045542,0045667,0045722,0045879,0046827,0048240,0048471,0050804,0051726,0061136,0070417,0070613,0071333,0071374,0071377,0097546,0098794,0098978,0099170,0106310,1904262,1904539,1990044,2000810 P25321 401 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGDTSNFDDYEEEEIRVEKCGKEFTEF 6ep0 A 2.35 BS01 AMP A 1 K78 F83 N115 H118 E122 N124 G125 M158 E159 E197 K70 F75 N107 H110 E114 N116 G117 M150 E151 E189 30850593 301 LENKLGIINQLELNRVEERVSKENAKRLYDSGDIDRIEVGTFKGLSYIHNYLFEDIYEFAGKVRSQNISKGNFRFAPVMYLEIALEHIDKMPQRNLDEIVAKYVEMNIAHPFREGNGRATRIWLDLILKKELKRVVDWNLINKEDYLSAMERSPVKDLEIKYLISNALTDKINDREIFMKGIDISYYYEGYTEYNVDEL 6ep0 B 2.35 BS01 AMP B 1 K78 N115 H118 N124 G125 Y154 M158 E159 E197 K72 N109 H112 N118 G119 Y148 M152 E153 E191 30850593 301 HMLENKLGIINQLELNRVEERVSKENAKRLYDSGDIDRIEVGTFKGLSYIHNYLFEDIYEFAGKVRSQNISKGNFRFAPVMYLEIALEHIDKMPQRNLDEIVAKYVEMNIAHPFREGNGRATRIWLDLILKKELKRVVDWNLINKEDYLSAMERSPVKDLEIKYLISNALTDKINDREIFMKGIDISYYYEGYTEYNVDEL 6esa A 1.307 BS02 AMP A 1 G50 T51 V57 A70 M120 V123 E127 L173 T183 F327 G41 T42 V48 A61 M111 V114 E118 L164 T174 F318 D166 K168 N171 D184 T201 D157 K159 N162 D175 T192 2.7.11.11 0000287,0001669,0001707,0001843,0004672,0004674,0004679,0004691,0004712,0005524,0005634,0005737,0005739,0005813,0005829,0005886,0005930,0005952,0006397,0006468,0006611,0007189,0007193,0010737,0016310,0016607,0018105,0019901,0019904,0030145,0031594,0031625,0032024,0034237,0034605,0036126,0044853,0045542,0045667,0045722,0045879,0046827,0048240,0048471,0050804,0051726,0061136,0070417,0070613,0071333,0071374,0071377,0097546,0098794,0098978,0099170,0106310,1904262,1904539,1990044,2000810 P25321 401 SEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 6etd A 1.723 BS01 AMP A 1 E201 L202 I215 D217 S218 N219 G266 G267 G324 N325 E183 L184 I197 D199 S200 N201 G248 G249 G301 N302 2.10.1.1,2.7.7.75 0006777,0032324 Q39054 29717023 501 MIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVASDGPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPDGADAVVQVEDTKVIGDVSKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKVYPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKELEKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIRAKPGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDPIRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSSVSAIIVSDISAFSID 6etf A 1.781 BS01 AMP A 1 E201 L202 I215 S218 N219 G266 G267 G324 N325 E186 L187 I200 S203 N204 G251 G252 G304 N305 2.10.1.1,2.7.7.75 0006777,0032324 Q39054 29717023 501 MIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVASDGPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPDGADAVVQVEDTKVIGDVSTESKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKVYPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKELEKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIRAKPGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDPIRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSSVSAIIVSDISAFSID 6eth A 1.64 BS01 AMP A 1 E201 L202 I215 S218 N219 G266 G267 S269 G324 N325 E186 L187 I200 S203 N204 G251 G252 S254 G304 N305 2.10.1.1,2.7.7.75 0006777,0032324 Q39054 29717023 501 MIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVASDGPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPDGADAVVQVEDTKVIGDVSTESKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKVYPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKELEKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIRAKPGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDPIRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSSVSAIIVSDISAFSID 6ezu B 2.04 BS02 AMP B 1 H417 D458 M530 D575 L576 N578 L593 Q626 F629 H83 D124 M196 D232 L233 N235 L250 Q283 F286 0004114,0007165,0008081 703 LPIHGVETPNDNELEERFSLCLDEWGVDIFEIDRLSNGHALTTVAYRIFQKRDLLKTFCIDPHVFVRYLLRVESTYHADVPYHNSMHAADVLQTAHFLLQAEALDDVFSDLEILAVLFAAAIHDVDHPGVTNQFLINTGHELALQYNDASVLENHHLYMAFKILTEKDCDIFANLGGKKRQTLRRMVIELVLATDMSKHMSLLADLRTMVETNLDNYADRIQILQNMIHCADLSNPAKPLRLYRKWTGRLIEEFFRQGDKERELSLEISPMCDRESVEVEKSQVSFIDFVCHPLWETWCDLVHPCAQLILDTLEDNRDWYECHI 6f2v A 2.5 BS01 AMP A 1 D168 T206 F207 Y290 Y321 D326 H483 D25 T63 F64 Y147 Y178 D183 H338 3.1.4.1,3.6.1.9 0003676,0016787,0046872 P97675 30022031 1001 WVTEACAPQCPEGFDQPPVILFSMDGFRAEYLQTWSTLLPNINKLKTCGLHSKYMRAVYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMYQGLKAASYYWPGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWLDLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPEINFYMYQGPAPRIRTRNIPQDFFTFNSEEIVRDLSCRKSDQHFKPYLTPDLPKRLHYAKNVRIDKVHLMVDRQWLAYRNKGNCEGGTHGYNNEFKSMEAIFLAHGPSFKEKTVIEPFENIEVYNLLCDLLHIQPAPNNGSHGSLNHLLKAPFYQPSHAEELSKSAGCGFTTPLPKDSLNCSCLALQEEQVNQRLNLNRGEVSATEKTNLPFGRPRVIQKNKDHCLLYHREYVSGFGKAMKMPMWSSYTVPKPGDTSSLPPTVPDCLRADVRVDPSESQKCSFYLADQNIDHGFLYPPAIKGNNESQYDALITSNLVPMYKEFKKMWDYFHKVLLIKYAIERNGVNVVSGPIFDYNYDGHFDAPDEITNYVAGTDVPVPTHYFVVLTSCKNKTHTPDSCPGWLDVLPFVVPHRPTNVESCPENKAEDLWVEERFKAHIARVRDVELLTGLDFYQEKTQPVSEILQLKTYLPTF 6f2v B 2.5 BS01 AMP B 1 D168 T206 F207 Y290 Y321 D326 H483 D24 T62 F63 Y146 Y177 D182 H337 3.1.4.1,3.6.1.9 0003676,0016787,0046872 P97675 30022031 1001 WVTEACAQCPEGFDQPPVILFSMDGFRAEYLQTWSTLLPNINKLKTCGLHSKYMRAVYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMYQGLKAASYYWPGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWLDLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPEINFYMYQGPAPRIRTRNIPQDFFTFNSEEIVRDLSCRKSDQHFKPYLTPDLPKRLHYAKNVRIDKVHLMVDRQWLAYRNKGNCEGGTHGYNNEFKSMEAIFLAHGPSFKEKTVIEPFENIEVYNLLCDLLHIQPAPNNGSHGSLNHLLKAPFYQPSHAEELSKSAGCGFTTPLPKDSLNCSCLALQEEQVNQRLNLNRGEVSATEKTNLPFGRPRVIQKNKDHCLLYHREYVSGFGKAMKMPMWSSYTVPKPGDTSSLPPTVPDCLRADVRVDPSESQKCSFYLADQNIDHGFLYPPAIKGNNESQYDALITSNLVPMYKEFKKMWDYFHKVLLIKYAIERNGVNVVSGPIFDYNYDGHFDAPDEITNYVAGTDVPVPTHYFVVLTSCKNKTHTPDSCPGWLDVLPFVVPHRPTNVESCPENKAEDLWVEERFKAHIARVRDVELLTGLDFYQEKTQPVSEILQLKTYLPTF 6fcl A 1.5 BS01 AMP A 1 F26 R27 R67 D128 L129 A131 T132 G133 T135 F24 R25 R65 D126 L127 A129 T130 G131 T133 2.4.2.7 0002055,0003999,0005515,0005576,0005654,0005737,0005829,0006166,0006168,0007625,0016208,0016757,0032263,0032264,0034774,0044209,0046083,0070062 -logKd/Ki=4.64, Ki=23uM P07741 29576532 200 DSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 6fcl B 1.5 BS01 AMP B 1 F26 R27 R67 D127 D128 L129 A131 T132 G133 T135 F24 R25 R65 D120 D121 L122 A124 T125 G126 T128 2.4.2.7 0002055,0003999,0005515,0005576,0005654,0005737,0005829,0006166,0006168,0007625,0016208,0016757,0032263,0032264,0034774,0044209,0046083,0070062 -logKd/Ki=4.64, Ki=23uM P07741 29576532 200 DSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 6fd5 A 1.55 BS01 AMP A 1 F26 R27 R67 D127 D128 L129 A131 T132 G133 T135 F24 R25 R65 D120 D121 L122 A124 T125 G126 T128 2.4.2.7 0002055,0003999,0005515,0005576,0005654,0005737,0005829,0006166,0006168,0007625,0016208,0016757,0032263,0032264,0034774,0044209,0046083,0070062 P07741 29576532 201 DSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 6fd5 B 1.55 BS03 AMP B 1 F26 R27 R67 D127 D128 L129 A131 T132 G133 G134 T135 F23 R24 R64 D118 D119 L120 A122 T123 G124 G125 T126 2.4.2.7 0002055,0003999,0005515,0005576,0005654,0005737,0005829,0006166,0006168,0007625,0016208,0016757,0032263,0032264,0034774,0044209,0046083,0070062 P07741 29576532 201 SELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 6fd6 A 1.8 BS01 AMP A 1 F26 R27 R67 D127 D128 L129 A131 T132 G133 T135 F24 R25 R65 D125 D126 L127 A129 T130 G131 T133 2.4.2.7 0002055,0003999,0005515,0005576,0005654,0005737,0005829,0006166,0006168,0007625,0016208,0016757,0032263,0032264,0034774,0044209,0046083,0070062 P07741 29576532 200 DSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEFGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 6fd6 B 1.8 BS01 AMP B 1 F26 R27 R67 D127 D128 L129 A131 T132 G133 T135 F24 R25 R65 D125 D126 L127 A129 T130 G131 T133 2.4.2.7 0002055,0003999,0005515,0005576,0005654,0005737,0005829,0006166,0006168,0007625,0016208,0016757,0032263,0032264,0034774,0044209,0046083,0070062 P07741 29576532 201 DSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEFGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 6fd9 A 2.2 BS01 AMP A 1 R32 A113 C115 V177 V178 D179 T180 T183 R12 A93 C95 V157 V158 D159 T160 T163 2.4.2.17 0000105,0003879,0005524,0005737,0016757 Q4FQF7 500 FLGLTLALSKGRILEETMPLLRAAGVELLEDPEASRKLIFPTSNPNVRVLILRASDVPTYVEHGAADFGVAGKDVLLEHGANHVYELLDLKIAQCKLMTAGVKDAPLPNRRLRIATKYVNVARAYFASQGQQVDVIKLYGSMELAPLVGLGDLIVDVVDTGNTLRANGLEARDHICDVSSRLIVNQVSYKRKFALLEPILDSFKNSINS 6gax A 1.77 BS01 AMP A 1 E201 L202 I215 D217 S218 N219 G266 G267 S269 G324 N325 E183 L184 I197 D199 S200 N201 G248 G249 S251 G301 N302 2.10.1.1,2.7.7.75 0032324 Q39054 29717023 501 EMIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVASDGPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPDGADAVVQVEDTKVIGDSKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKVYPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKELEKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMAPGKPLTFAEIRAKPGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDPIRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSSVSAIIVSDISAFSID 6gb0 A 1.814 BS01 AMP A 1 E201 L202 I215 D217 S218 N219 G266 G267 G324 N325 E183 L184 I197 D199 S200 N201 G248 G249 G301 N302 2.10.1.1,2.7.7.75 0032324 Q39054 29717023 501 MIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVASDGPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPDGADAVVQVEDTKVIGDVSKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKVYPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKELEKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMAPGKPLTFAEIRAKPGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDPIRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSSVSAIIVSDISAFSID 6gb4 A 1.648 BS01 AMP A 1 S197 E201 L202 I215 S218 N219 G266 G267 S269 G324 N325 S178 E182 L183 I196 S199 N200 G247 G248 S250 G300 N301 2.10.1.1,2.7.7.75 0006777,0032324 Q39054 29717023 501 MIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVASDGPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPDGADAVVQVEDTKVIGDSKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKVYPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKELEKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIRAKPGKTVLAFGLPGNPVACLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDPIRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSSVSAIIVSDISAFSID 6gb9 A 1.67 BS01 AMP A 1 E201 L202 I215 S218 N219 G266 G267 G324 N325 E183 L184 I197 S200 N201 G248 G249 G301 N302 2.10.1.1,2.7.7.75 0006777,0032324 Q39054 29717023 501 MIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVASDGPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPDGADAVVQVEDTKVIGDVSKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKVYPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKELEKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIRAKPGKTVLAFGLPGNPVACLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDPIRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSSVSAIIVSDISAFSID 6gbc A 1.59 BS01 AMP A 1 S197 E201 L202 I215 D217 S218 N219 G266 G267 G324 N325 S183 E187 L188 I201 D203 S204 N205 G252 G253 G305 N306 2.10.1.1,2.7.7.75 0006777,0032324 Q39054 29717023 501 EMIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVASDGPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPDGADAVVQVEDTKVIGDVSTESKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKVYPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKELEKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIRAKPGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDPIAPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSSVSAIIVSDISAFSID 6gbf A 1.712 BS01 AMP A 1 E201 L202 I215 S218 N219 G266 G267 S269 G324 N325 E182 L183 I196 S199 N200 G247 G248 S250 G300 N301 2.10.1.1,2.7.7.75 0006777,0032324 Q39054 29717023 501 MIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVASDGPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPDGADAVVQVEDTKVIGDSKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKVYPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKELEKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIRAKPGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDPIAPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSSVSAIIVSDISAFSID 6gdr A 2.33 BS04 AMP D 1 K34 L35 R39 R50 E73 M191 K209 K26 L27 R31 R42 E65 M157 K175 0003910,0005524,0006281,0006310 30007325 300 IVDGLQLAKQYGHQDINIAEYWVSEKLDGIRARWDGTELRTRNNNKIDAPAWFTANWPKATIDGELWIARGQFERTASIVLSKLTLPSKRWAKVRFMAFDMPVAGQSFDSRLNMLNNLKEATPNPTFAVVSQFTLSSVNALEEKLEQVTLSGGEGLMLHHKKAFYHSGRSDKLIKVKQFEDAEAKVLAHFAGKGKFKGMMGSLLVETPAGVQFKLGTGFSEKERRAPPAVGSWVTFKFYGVTKNGKPRFASFLRVR 6gpb A 2.86 BS06 AMP A 1 F285 E572 Y613 M615 F272 E559 Y600 M602 H377 K568 R569 K574 T676 K680 H364 K555 R556 K561 T663 K667 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 2106586 913 SVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDEKI 6gpb A 2.86 BS07 AMP A 2 Y75 R310 Y62 R297 H377 K568 R569 K574 T676 K680 H364 K555 R556 K561 T663 K667 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 2106586 997 SVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDEKI 6h1b A 2.8 BS01 AMP A 1 G271 A272 P273 Q292 N293 Y294 Q297 D377 R392 R407 G264 A265 P266 Q285 N286 Y287 Q290 D370 R385 R400 T158 D201 Q297 E298 I398 N403 A483 T157 D194 Q290 E291 I391 N396 A476 ? 0000166,0016874 R4R1U5 30035356 501 PAMGYARRVMDGIGEVAVTGAGGSVTGARLRHQVRLLAHALTEAGIPPGRGVACLHANTWRAIALRLAVQAIGCHYVGLRPTAAVTEQARAIAAADSAALVFEPSVEARAADLLERVSVPVVLSLGPTSRGRDILAPEGTPLRYREHPEGIAVVAFTPKGVAHSSTAMSACVDAAVSMYGRGPWRFLIPIPLSDLGGELAQCTLATGGTVVLLEEFQPDAVLEAIERERATHVFLAPNWLYQLAEHPALPRSDLSSLRRVVYGGAPAVPSRVAAARERMGAVLMQNYGTQEAAFIAALTPDDHARRELLTAVGRPLPHVEVEIRDDSGGTLPRGAVGEVWVRSPMTMSGYWRDPERTAQVLSGGWLRTGDVGTFDEDGHLHLTDRLQDIIIVEAYNVYSRRVEHVLTEHPDVRAAAVVGVPDPDSGEAVCAAVVVADGADPDPEHLRALVRDHLGDLHVPRRVEFVRSIPVTPAGAPDKVKVRTWFT 6h1b B 2.8 BS01 AMP B 1 G271 A272 Q292 Y294 Q297 V319 D377 R392 R407 G264 A265 Q285 Y287 Q290 V312 D370 R385 R400 T158 D201 Q297 E298 I398 N403 A483 T155 D194 Q290 E291 I391 N396 A474 ? 0000166,0016874 R4R1U5 30035356 501 PAMGYARRVMDGIGEVAVTGAGGSVTGARLRHQVRLLAHALTEAGIPPGRGVACLHANTWRAIALRLAVQAIGCHYVGLRPTAAVTEQARAIAAADSAALVFEPSVEARAADLLERVSVPVVLSLGPTSRGRDILEGTPLRYREHPEGIAVVAFTGTPKGVAHSSTAMSACVDAAVSMYGRGPWRFLIPIPLSDLGGELAQCTLATGGTVVLLEEFQPDAVLEAIERERATHVFLAPNWLYQLAEHPALPRSDLSSLRRVVYGGAPAVPSRVAAARERMGAVLMQNYGTQEAAFIAALTPDDHARRELLTAVGRPLPHVEVEIRDDSGGTLPRGAVGEVWVRSPMTMSGYWRDPERTAQVLSGGWLRTGDVGTFDEDGHLHLTDRLQDIIIVEAYNVYSRRVEHVLTEHPDVRAAAVVGVPDPDSGEAVCAAVVVADGADPDPEHLRALVRDHLGDLHVPRRVEFVRSIPVAGAPDKVKVRTWFT 6h1b C 2.8 BS01 AMP C 1 G271 A272 P273 Q292 N293 Y294 G295 D377 R392 R407 G266 A267 P268 Q287 N288 Y289 G290 D372 R387 R402 T158 D201 Q297 E298 I398 N403 A483 T158 D196 Q292 E293 I393 N398 A478 ? 0000166,0016874 R4R1U5 30035356 501 PAMGYARRVMDGIGEVAVTGAGGSVTGARLRHQVRLLAHALTEAGIPPGRGVACLHANTWRAIALRLAVQAIGCHYVGLRPTAAVTEQARAIAAADSAALVFEPSVEARAADLLERVSVPVVLSLGPTSRGRDILAASVPTPLRYREHPEGIAVVAFTSGPKGVAHSSTAMSACVDAAVSMYGRPWRFLIPIPLSDLGGELAQCTLATGGTVVLLEEFQPDAVLEAIERERATHVFLAPNWLYQLAEHPALPRSDLSSLRRVVYGGAPAVPSRVAAARERMGAVLMQNYGTQEAAFIAALTPDDHARRELLTAVGRPLPHVEVEIRDDSGGTLPRGAVGEVWVRSPMTMSGYWRDPERTAQVLSGGWLRTGDVGTFDEDGHLHLTDRLQDIIIVEAYNVYSRRVEHVLTEHPDVRAAAVVGVPDPDSGEAVCAAVVVADGADPDPEHLRALVRDHLGDLHVPRRVEFVRSIPVTPAGAPDKVKVRTWFTD 6h1b D 2.8 BS01 AMP D 1 G271 A272 Q292 N293 Y294 G295 Q297 V319 D377 L389 R392 R407 G264 A265 Q285 N286 Y287 G288 Q290 V312 D370 L382 R385 R400 T158 D201 Q297 E298 I398 N403 A483 T156 D194 Q290 E291 I391 N396 A476 ? 0000166,0016874 R4R1U5 30035356 501 QGPAMGYARRVMDGIGEVAVTGAGGSVTGARLRHQVRLLAHALTEAGIPPGRGVACLHANTWRAIALRLAVQAIGCHYVGLRPTAAVTEQARAIAAADSAALVFEPSVEARAADLLERVSVPVVLSLGPTSRGRDILATPLRYREHPEGIAVVAFTTPKGVAHSSTAMSACVDAAVSMYGRGPWRFLIPIPLSDLGGELAQCTLATGGTVVLLEEFQPDAVLEAIERERATHVFLAPNWLYQLAEHPALPRSDLSSLRRVVYGGAPAVPSRVAAARERMGAVLMQNYGTQEAAFIAALTPDDHARRELLTAVGRPLPHVEVEIRDDSGGTLPRGAVGEVWVRSPMTMSGYWRDPERTAQVLSGGWLRTGDVGTFDEDGHLHLTDRLQDIIIVEAYNVYSRRVEHVLTEHPDVRAAAVVGVPDPDSGEAVCAAVVVADGADPDPEHLRALVRDHLGDLHVPRRVEFVRSIPVTPAGAPDKVKVRTWFT 6h1b E 2.8 BS01 AMP E 1 G271 A272 P273 Y294 D377 N403 G264 A265 P266 Y287 D370 N396 T158 D201 Q297 E298 I398 N403 A483 T153 D194 Q290 E291 I391 N396 A475 ? 0000166,0016874 R4R1U5 30035356 501 MGYARRVMDGIGEVAVTGAGGSVTGARLRHQVRLLAHALTEAGIPPGRGVACLHANTWRAIALRLAVQAIGCHYVGLRPTAAVTEQARAIAAADSAALVFEPSVEARAADLLERVSVPVVLSLGPTSRGRDIPEGTPLRYREHPEGIAVVAFTTTGTPKGVAHSSTAMSACVDAAVSMYGRGPWRFLIPIPLSDLGGELAQCTLATGGTVVLLEEFQPDAVLEAIERERATHVFLAPNWLYQLAEHPALPRSDLSSLRRVVYGGAPAVPSRVAAARERMGAVLMQNYGTQEAAFIAALTPDDHARRELLTAVGRPLPHVEVEIRDDSGGTLPRGAVGEVWVRSPMTMSGYWRDPERTAQVLSGGWLRTGDVGTFDEDGHLHLTDRLQDIIIVEAYNVYSRRVEHVLTEHPDVRAAAVVGVPDPDSGEAVCAAVVVADADPDPEHLRALVRDHLGDLHVPRRVEFVRSIPVTPAGAPDKVKVRTWFTD 6he0 A 2.31 BS02 AMP A 1 G240 E241 P242 C264 G265 S266 A268 E269 D333 N369 G242 E243 P244 C266 G267 S268 A270 E271 D335 N371 6.2.1.- 0000166,0016874 I3VE75 31145912 1002 SGMEEWNFPVEYDENYLPPADSRYWFPRRETMPAAERDKAILGRLQQVCQYAWEHAPFYRRKWEEAGFQPSQLKSLEDFEARVPVVKKTDLRESQAAHPPFGDYVCVPNSEIFHVHGTSGTTGRPTAFGIGRADWRAIANAHARIMWGMGIRPGDLVCVAAVFSLYMGSWGALAGAERLRAKAFPFGAGAPGMSARLVQWLDTMKPAAFYGTPSYAIHLAEVAREEKLNPRNFGLKCLFFSGEPGASVPGVKDRIEEAYGAKVYDCGSMAEMSPFMNVAGTEQSNDGMLCWQDIIYTEVCDPANMRRVPYGQRGTPVYTHLERTSQPMIRLLSGDLTLWTNDENPCGRTYPRLPQGIFGRIDDMFTIRGENIYPSEIDAALNQMSGYGGEHRIVITRESAMDELLLRVEPSESVHAAGAAALETFRTEASHRVQTVLGVRAKVELVAPNSIARTDKARRVIDDREVFRALNQQLQSS 6he2 A 2.3 BS01 AMP A 1 K86 G240 E241 P242 C264 S266 M267 A268 E269 D333 I355 K91 G241 E242 P243 C265 S267 M268 A269 E270 D334 I356 6.2.1.- 0000166,0016874 I3VE75 31145912 501 HHHSGMEEWNFPVEYDENYLPPADSRYWFPRRETMPAAERDKAILGRLQQVCQYAWEHAPFYRRKWEEAGFQPSQLKSLEDFEARVPVVKKTDLRESQAAHPPFGDYVCVPNSEIFHVHGTSRPTAFGIGRADWRAIANAHARIMWGMGIRPGDLVCVAAVFSLYMGSWGALAGAERLRAKAFPFGAGAPGMSARLVQWLDTMKPAAFYGTPSYAIHLAEVAREEKLNPRNFGLKCLFFSGEPGASVPGVKDRIEEAYGAKVYDCGSMAEMSPFMNVAGTEQSNDGMLCWQDIIYTEVCDPANMRRVPYGQRGTPVYTHLERTSQPMIRLLSGDLTLWTNDENPCGRTYPRLPQGIFGRIDDMFTIRGENIYPSEIDAALNQMSGYGGEHRIVITRMDELLLRVEPSESVHAAGAAALETFRTEASHRVQTVLGVRAKVELVAPNSIARTDFKARRVIDD 6he2 B 2.3 BS01 AMP B 1 K86 G240 E241 P242 C264 S266 M267 A268 E269 D333 I355 K89 G240 E241 P242 C264 S266 M267 A268 E269 D333 I355 6.2.1.- 0000166,0016874 I3VE75 31145912 501 HSGMEEWNFPVEYDENYLPPADSRYWFPRRETMPAAERDKAILGRLQQVCQYAWEHAPFYRRKWEEAGFQPSQLKSLEDFEARVPVVKKTDLRESQAAHPPFGDYVCVPNSEIFHVHGTSGRPTAFGIGRADWRAIANAHARIMWGMGIRPGDLVCVAAVFSLYMGSWGALAGAERLRAKAFPFGAGAPGMSARLVQWLDTMKPAAFYGTPSYAIHLAEVAREEKLNPRNFGLKCLFFSGEPGASVPGVKDRIEEAYGAKVYDCGSMAEMSPFMNVAGTEQSNDGMLCWQDIIYTEVCDPANMRRVPYGQRGTPVYTHLERTSQPMIRLLSGDLTLWTNDENPCGRTYPRLPQGIFGRIDDMFTIRGENIYPSEIDAALNQMSGYGGEHRIVLLLRVEPSESVHAAGAAALETFRTEASHRVQTVLGVRA 6hvl B 2.8 BS01 AMP B 1 L31 D71 Y87 L88 T102 R103 L30 D70 Y86 L87 T101 R102 2.7.7.85 0004016,0006171 Q8Y5E4 31118276 201 GSRIEREQHHLIESIEKSTQYMAKRRIGALISVARDTGMDDYIETGIPLNAKISSQLLINIFIPNTPLHDGAVIIKGNEIASAASYLPLSDSPFLSKELGTRHRAALGISEVTDSITIVVSEETGGISLTKGGELFRDVSEEELHKILLKELVT 6iii A 2.113 BS02 AMP A 1 Y71 Q75 G84 G86 R87 S115 R116 G118 D119 G120 D246 N247 Y68 Q72 G81 G83 R84 S112 R113 G115 D116 G117 D243 N244 2.7.7.108 0000287,0005524,0016779,0018117,0046872,0070733 P77649 502 TLSFITRWRDELPATYTTLSPTPLNNARLIWHNAELANTLGIPSSLFKAGVWGGETLLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQRLADGTTMDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETVEPGAMLMRVAPSHLRFGHFEHFYYRREPEKVRQLADFAIRHYWSHLADDEDKYRLWFTDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSDHQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGQRMRQKLGFMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAADEFIDRAAFDDWFARYRGRLQQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRDDDYVSRPPD 6ijb B 2.111 BS01 AMP B 1 G303 A304 A305 H324 W326 G327 M328 S329 Q359 D417 G303 A304 A305 H324 W326 G327 M328 S329 Q359 D417 T185 H205 H231 S329 E330 K438 W443 A523 T185 H205 H231 S329 E330 K438 W443 A523 30677184 601 MLGQMMTQPLLISSLIDHAARYHGQTEIVSVETDGTVTRTNWGEIAANARRMGSALTKLGLQPQDRIGTLAWNNRRHLEIYYAASGAGFVCHTINPRLFPEQLVYIINHAQDRVLFFDATFLPLVAAIRDQLTEVKHFVLMGPRNEDALQQIPGLEFYDELIETGDTDFEWPVFDENTASSLCYTSGTTGHPKGVLYSHRSTVLHSFASNTRDVIGYSAMDVVMPVVPMFHVNAWGSPYGCAMSGAQMVLPGPDLHGEALVNLIDTYGVTLAMGVPTIWQGLLAHAAKCGTKLESLERTVIGGAACPPSMIATFREKYGVDTVHAWGMSEMSPLGTANIPLAKHRKLPIEEQHKLRENQGRPPFGVELKIVDDDGNDLPHDGVTQGDLMVRGHWVLDSYFQLKDQELLQDGWFATGDVATLDPDGYMTIRDRSKDIIKSGGEWISSVELENIAVAHPKLATAAVIGVPHPKWDERPLLVAVKAEGEDPSEAELLEFFDGKIAKWQVPDKVVFVDALPLNATGAVLKRKLRDEFKDALT 6ito A 2.55 BS04 AMP A 1 R351 F373 T374 Q375 S376 T379 K418 M419 P453 G454 T455 G457 S458 R350 F372 T373 Q374 S375 T378 K417 M418 P452 G453 T454 G456 S457 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 31381898 504 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 6ito B 2.55 BS04 AMP B 1 R351 F373 T374 Q375 S376 T379 K418 M419 M425 G450 P453 G454 T455 G457 S458 R350 F372 T373 Q374 S375 T378 K417 M418 M424 G449 P452 G453 T454 G456 S457 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 31381898 504 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 6ito C 2.55 BS04 AMP C 1 R351 F373 T374 Q375 S376 T379 K418 M419 M425 G450 P453 G454 T455 G457 S458 R350 F372 T373 Q374 S375 T378 K417 M418 M424 G449 P452 G453 T454 G456 S457 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 31381898 504 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 6ito D 2.55 BS04 AMP D 1 R351 F373 T374 Q375 S376 T379 K418 M419 M425 G450 G454 T455 G457 S458 R350 F372 T373 Q374 S375 T378 K417 M418 M424 G449 G453 T454 G456 S457 R33 R74 K218 T276 R32 R73 K217 T275 2.7.1.40 0000287,0003824,0004743,0005524,0005737,0005829,0005886,0006096,0016301,0016310,0030955,0046872 P9WKE5 31381898 504 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 6j53 B 1.52 BS01 AMP B 1 D43 I44 Q106 S107 V108 H112 H114 D32 I33 Q95 S96 V97 H101 H103 3.4.22.-,3.9.1.- 0000118,0000166,0003824,0005080,0005515,0005634,0005654,0005737,0005829,0005856,0005886,0006355,0006508,0006915,0007165,0008234,0009154,0016787,0016926,0016929,0043530,0050850,0070062,0072332 P49773 31604935 201 RPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 6j58 B 1.521 BS01 AMP B 1 I18 D43 I44 G105 Q106 S107 V108 H112 H114 I7 D32 I33 G94 Q95 S96 V97 H101 H103 3.4.22.-,3.9.1.- 0000118,0000166,0003824,0005080,0005515,0005634,0005654,0005737,0005829,0005856,0005886,0006355,0006508,0006915,0007165,0008234,0009154,0016787,0016926,0016929,0043530,0050850,0070062,0072332 P49773 31604935 201 RPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 6jwq B 2.5 BS01 AMP B 1 D208 D210 I211 N312 E314 F315 L316 S317 H320 D162 D164 I165 N207 E209 F210 L211 S212 H215 2.5.1.15,2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0042558,0044237,0046654,0046656,0046872 Q25704 31883412 801 ELILSEENKTNIAVLNLGTNDRRNAVLILETALHLVEKYLGKIINTSYLYETVPEYIDVNYINELMQNLEESKYEENKELIDKCEEYETFLKNGKVDNSILKEVNVENYLLECNNIIVKNDEIMKNSYFYNLTVVVKTFVNDPLSMLVVIKYIEELMKRIIDIDILFFNDFTIFMKNIKLEKNMIYKILSKYIHLDPQEIINNMVDNIEFLSIPHVYTTHRYSILLCLNDMIPEYKHNVLNNTIRCLYNKYVSRMKEQYNINIKENNKRIYVLKDRISYLKEKTNIVGILNVNYDSFSDGGIFVEPKRAVQRMFEMINEGASVIDIGGESSAPFVIPNPKISERDLVVPVLQLFQKEWNDIKNKIVKCDAKPIISIDTINYNVFKECVDNDLVDILNDISACTNNPEIIKLLKKKNKFYSVVLMHKRGNPHTMDKLTNYDNLVYDIKNYLEQRLNFLVLNGIPRYRILFDIGLGFAKKHDQSIKLLQNIHVYDEYPLFIGYSRKRFIAHCMNDQWMFQMNYMRKDKDQLLYQKNICGGLAIASYSYYKKVDLIRVHDVLETKSVLDVLTKIDQVKDPNSSSVDKLAAALE 6jwr A 2.6 BS02 AMP A 1 L181 I211 N312 F315 L316 S317 H320 L154 I171 N210 F213 L214 S215 H218 2.5.1.15,2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0042558,0044237,0046654,0046656,0046872 Q25704 31883412 802 IQELILSEENKTNIAVLNLGTNDRRNAVLILETALHLVEKYLGKIINTSYLYETVPEYIVLDDVNYINELMQNLEESKYEENKELIDKCEEYETFLKNGKVDNSILKEVNVENYLLECNNIIVKNDEIMKNNTSYFYNLTVVVKTFVNDPLSMLVVIKYIEELMKIIDIDILFFNDFTIFMKNIKLEKNMIYKILSKYIHLEIINNMVDNIEFLSIPHVYTTHRYSILLCLNDMIPEYKHNVLNNTIRCLYNKYVSRMKEQYNINIKENNKRIYVLKDRISYLKEKTNIVGILNVNIFVEPKRAVQRMFEMINEGASVIDIGGESSAPFVIPNPKISERDLVVPVLQLFQKEWNDIAKPIISIDTINYNVFKECVDNDLVDILNDISACTNNPEIIKLLKKKNKFYSVVLMHKRGNPHTMDKLTNYDNLVYDIKNYLEQRLNFLVLNGIPRYRILFDIGLGFAKKHDQSIKLLQNIHVYDEYPLFIGYSRKRFIAHCMNDKDQLLYQKNICGGLAIASYSYYKKVDLIRVHDVLETKSVLDVLTKIDQV 6jwr B 2.6 BS02 AMP B 1 L181 K185 D208 I211 F315 L316 S317 H320 L142 K146 D156 I159 F197 L198 S199 H202 2.5.1.15,2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0042558,0044237,0046654,0046656,0046872 Q25704 31883412 802 LSEENKTNIAVLNLGTNDRRNAVLILETALHLVEKYLGKIINTSYLYETVPEYINYINELMQNLEESKYEENKELIDKCEEYETFLKNGKVDNSILKEVNVENYLLECNNIIVKNDEIMKNSYFYNLTVVVKTFVNDPLSMLVVIKYIEELMKIIDIDILFFNDFTIFMKNIYKILSKYIHLDPQEIINNMVDNIEFLSIPHVYTTHRYSILLCLNDMIPEYKHNVLNNTIRCLYNKYVSRMKEQYNINIKENNKRIYVLKDRISYLKEKTNIVGILNVNYGIFVEPKRAVQRMFEMINEGASVIDIGGESSAPFVIPNPKISERDLVVPVLQLFQKEWNDAKPIISIDTINYNVFKECVDNDLVDILNDISACTNNPEIIKLLKKKNKFYSVVLMHKRGNPHTMDKLTNYDNLVYDIKNYLEQRLNFLVLNGIPRYRILFDIGLGFAKKHDQSIKLLQNIHVYDEYPLFIGYSRKRFIAHCMDKDQLLYQKNICGGLAIASYSYYKKVDLIRVHDVLETKSVLDVLTKIDQVKDPNSSSVDKLAAALE 6jwt A 2.56 BS01 AMP A 1 L181 D210 I211 N312 F315 L316 S317 H320 L138 D154 I155 N201 F204 L205 S206 H209 2.5.1.15,2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0042558,0044237,0046654,0046656,0046872 Q25704 31883412 801 LILSEENKTNIAVLNLGTNDRRNAVLILETALHLVEKYLGKIINTSYLYETVPVNYINELMQNLEESKYEENKELIDKCEEYETFLKNGKVDNSILKEVNVENYLLECNNIIVKNDESYFYNLTVVVKTFVNDPLSMLVVIKYIEELMKIIDIDILFFNDFTIFMKNIKLEKNMIYKILSKYIHLERFRDPQEIINNMVDNIEFLSIPHVYTTHRYSILLCLNDMIPEYKHNVLNNTIRCLYNKYVSRMKEQYNINIKENNKRIYVLKDRISYLKEKTNIVGILNVNVEPKRAVQRMFEMINEGASVIDIGGESFGPFVIPNPKISERDLVVPVLQLFQKEWNDIKNKIVKCDAKPIISIDTINYNVFKECVDNDLVDILNDISACTNNPEIIKLLKKKNKFYSVVLMHKRGNPHTMDKLTNYDNLVYDIKNYLEQRLNFLVLNGIPRYRILFDIGLGFAKKHDQSIKLLQNIHVYDEYPLFIGYSRKRFITHCMNDKDQLLYQKNICGGLAIASYSYYKKVDLIRVHDVLETKSVLDVLTKIDQVKD 6jwu A 2.65 BS03 AMP A 1 L181 D208 D210 I211 N312 E314 F315 L316 S317 H320 L150 D164 D166 I167 N210 E212 F213 L214 S215 H218 2.5.1.15,2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0042558,0044237,0046654,0046656,0046872 Q25704 31883412 804 ETIQELILSEENKTNIAVLNLGTNDRRNAVLILETALHLVEKYLGKIINTSYLYETVPEYIVNYINELMQNLEESKYEENKELIDKCEEYETFLKNGKVDNSILKEVNVENYLLECNNIIVKNDEIMKNSYFYNLTVVVKTFVNDPLSMLVVIKYIEELMKIIDIDILFFNDFTIFMKNIKLEKNMIYKILSKYIHLEDPQEIINNMVDNIEFLSIPHVYTTHRYSILLCLNDMIPEYKHNVLNNTIRCLYNKYVSRMKEQYNINIKENNKRIYVLKDRISYLKEKTNIVGILNVNGIFVEPKRAVQRMFEMINEGASVIDIGGESSAPFVIPNPKISERDLVVPVLQLFQKEWNDIIVKCDAKPIISIDTINYNVFKECVDNDLVDILNDISACTNNPEIIKLLKKKNKFYSVVLMHKRGNPHTMDKLTNYDNLVYDIKNYLEQRLNFLVLNGIPRYRILFDIGLGFAKKHDQSIKLLQNIHVYDEYPLFIGYSRKRFIAHCMNDDKDQLLYQKNICGGLAIASYSYYKKVDLIRVHDVLETKSVLDVLTKIDQVKD 6jwu B 2.65 BS02 AMP B 1 D208 I211 N312 I313 F315 S317 H320 D147 I150 N187 I188 F190 S192 H195 2.5.1.15,2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0042558,0044237,0046654,0046656,0046872 Q25704 31883412 803 QELILSEENKTNIAVLNLGTNDRRNAVLILETALHLVEKYLGKIINTSYLYETVPINELMQNLEESKYEENKELIDKCEEYETFLKNGKVDNSILKEVNVENYLLECNNIIVKNDFYNLTVVVKTFVNDPLSMLVVIKYIEELMIIDIDILFFNDFTIFMKNIKLEKNMIYKILSKYIHLINNMVDNIEFLSIPHVYTTHRYSILLCLNDMIPEYKHNVLNNTIRCLYNKYVSRMKEQYNINIKENNKRIYVLKDRISYLKEKTNIVGILNVNYVEPKRAVQRMFEMINEGASVIDIGGEKISERDLVVPVLQLFQKEWNDIKCDAKPIISIDTINYNVFKECVDNDLVDILNDISACTNNPEIIKLLKKKNKFYSVVLMHKRGNPHTMDKLTNYDNLVYDIKNYLEQRLNFLVLNGIPRYRILFDIGLGFAKKHDQSIKLLQNIHVYDEYPLFIGYSRKRFIAHCMNDKDQLLYQKNICGGLAIASYSYYKKVDLIRVHDVLETKSVLDVLTKIDQVKDPNSSSVDKLAAALE 6jww B 2.75 BS02 AMP B 1 L181 D208 D210 I211 N312 F315 L316 S317 H320 L142 D156 D158 I159 N200 F203 L204 S205 H208 2.5.1.15,2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0042558,0044237,0046654,0046656,0046872 Q25704 31883412 802 QELILSEENKTNIAVLNLGTNDRRNAVLILETALHLVEKYLGKIINTSYLYETVPEYIYINELMQNLEESKYEENKELIDKCEEYETFLKNGKVDNSILKEVNVENYLLECNNIIVKNDEIMYFYNLTVVVKTFVNDPLSMLVVIKYIEELMKIIDIDILFFNDFTIFMKNIKLEKNMIYKILSKYIHLEQEIINNMVDNIEFLSIPHVYTTHRYSILLCLNDMIPEYKHNVLNNTIRCLYNKYVSRMKEQYNINIKENNKRIYVLKDRISYLKEKTNIVGILNVNYFVEPKRAVQRMFEMINEGASVIDIGGESFGNPKISERDLVVPVLQLFQKEWNDIKNKIVKCDAKPIISIDTINYNVFKECVDNDLVDILNDISACTNNPEIIKLLKKKNKFYSVVLMHKRGNPHTMDKLTNYDNLVYDIKNYLEQRLNFLVLNGIPRYRILFDIGLGFAKKHDQSIKLLQNIHVYDEYPLFIGYSRKRFITHCMNDDKDQLLYQKNICGGLAIASYSYYKKVDLIRVHDVLETKSVLDVLTKIDQVKDPNSSSVDKLAAALE 6jwx A 2.5 BS03 AMP A 1 L181 D210 I211 N312 E314 F315 L316 S317 H320 L151 D168 I169 N208 E210 F211 L212 S213 H216 2.5.1.15,2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0042558,0044237,0046654,0046656,0046872 Q25704 31883412 803 IQELILSEENKTNIAVLNLGTNDRRNAVLILETALHLVEKYLGKIINTSYLYETVPEYIVVNYINELMQNLEESKYEENKELIDKCEEYETFLKNGKVDNSILKEVNVENYLLECNNIIVKNDEIMKNNTSYFYNLTVVVKTFVNDPLSMLVVIKYIEELMKRIIDIDILFFNDFTIFMKNIKLEKNMIYKILSKYIHLEIINNMVDNIEFLSIPHVYTTHRYSILLCLNDMIPEYKHNVLNNTIRCLYNKYVSRMKEQYNINIKENNKRIYVLKDRISYLKEKTNIVGILNVNYVEPKRAVQRMFEMINEGASVIDIGGESKISERDLVVPVLQLFQKEWNDIKNKIVKCDAKPIISIDTINYNVFKECVDNDLVDILNDISACTNNPEIIKLLKKKNKFYSVVLMHKRGNPHTMDKLTNYDNLVYDIKNYLEQRLNFLVLNGIPRYRILFDIGLGFAKKHDQSIKLLQNIHVYDEYPLFIGYSRKRFIAHCMNDQLLYQKNICGGLAIASYSYYKKVDLIRVHDVLETKSVLDVLTKIDQVK 6jwx B 2.5 BS02 AMP B 1 K185 D208 D210 I211 N312 I313 F315 L316 S317 H320 K133 D144 D146 I147 N185 I186 F188 L189 S190 H193 2.5.1.15,2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0042558,0044237,0046654,0046656,0046872 Q25704 31883412 802 TNIAVLNLGTNDRRNAVLILETALHLVEKYLGKIINTSYLYETVPNYINELMQNLEESKYEENKELIDKCEEYETFLKNGKVDNSILKEVNVENYLLECNNIIVKNDEIYFYNLTVVVKTFVNDPLSMLVVIKYIEELMKRIIDIDILFFNDFTIFMKNIKLEKNMIYKILSKYIHLIINNMVDNIEFLSIPHVYTTHRYSILLCLNDMIPEYKHNVLNNTIRCLYNKYVSRMKEQYNINIKENNKRIYVLKDRISYLKEKTNIVGILNVNEPKRAVQRMFEMINEGASVIDIGGEISERDLVVPVLQLFQKEWNDAKPIISIDTINYNVFKECVDNDLVDILNDISACTNNPEIIKLLKKKNKFYSVVLMHKRGNPHTMDKLTNYDNLVYDIKNYLEQRLNFLVLNGIPRYRILFDIGLGFAKKHDQSIKLLQNIHVYDEYPLFIGYSRKRFIAHCMNDKDQLLYQKNICGGLAIASYSYYKKVDLIRVHDVLETKSVLDVLTKIDQVKDPNSSSVDKLAAALEH 6jwz A 2.95 BS02 AMP A 1 D208 D210 I211 N312 F315 L316 S317 H320 D164 D166 I167 N209 F212 L213 S214 H217 2.5.1.15,2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0042558,0044237,0046654,0046656,0046872 Q25704 31883412 803 QELILSEENKTNIAVLNLGTNDRRNAVLILETALHLVEKYLGKIINTSYLYETVPEVNYINELMQNLEESKYEENKELIDKCEEYETFLKNGKVDNSILKEVNVENYLLECNNIIVKNDEIMKNNLSYFYNLTVVVKTFVNDPLSMLVVIKYIEELMKRERIIDIDILFFNDFTIFMKNIKLEKNMIYKILSKYIHLEPQEIINNMVDNIEFLSIPHVYTTHRYSILLCLNDMIPEYKHNVLNNTIRCLYNKYVSRMKEQYNINIKENNKRIYVLKDRISYLKEKTNIVGILNVNVEPKRAVQRMFEMINEGASVIDIGGESPNPKISERDLVVPVLQLFQKEWNDIKNKIVKCDAKPIISIDTINYNVFKECVDNDLVDILNDISACTNNPEIIKLLKKKNKFYSVVLMHKRGNPHTMDKLTNYDNLVYDIKNYLEQRLNFLVLNGIPRYRILFDIGLGFAKKHDQSIKLLQNIHVYDEYPLFIGYSRKRFISHCMNDKDQLLYQKNICGGLAIASYSYYKKVDLIRVHDVLETKSVLDVLTKIDQVKD 6jwz B 2.95 BS02 AMP B 1 D208 I211 N312 I313 E314 F315 L316 S317 H320 D159 I162 N202 I203 E204 F205 L206 S207 H210 2.5.1.15,2.7.6.3 0003848,0004156,0005524,0005740,0009396,0016301,0016310,0042558,0044237,0046654,0046656,0046872 Q25704 31883412 803 IQELILSEENKTNIAVLNLGTNDRRNAVLILETALHLVEKYLGKIINTSYLYETVPYINELMQNLEESKYEENKELIDKCEEYETFLKNGKVDNSILKEVNVENYLLECNNIIVKNDEIMKNNSYFYNLTVVVKTFVNDPLSMLVVIKYIEELMKRIIDIDILFFNDFTIFMKNIKLEKNMIYKILSKYIHLQEIINNMVDNIEFLSIPHVYTTHRYSILLCLNDMIPEYKHNVLNNTIRCLYNKYVSRMKEQYNINIKENNKRIYVLKDRISYLKEKTNIVGILNVNYDSFSDGGIFVEPKRAVQRMFEMINEGASVIDIGGESFKISERDLVVPVLQLFQKEWNDIKNKIVKCDAKPIISIDTINYNVFKECVDNDLVDILNDISACTNNPEIIKLLKKKNKFYSVVLMHKRGNPHTMDKLTNYDNLVYDIKNYLEQRLNFLVLNGIPRYRILFDIGLGFAKKHDQSIKLLQNIHVYDEYPLFIGYSRKRFISHCMNDKDQLLYQKNICGGLAIASYSYYKKVDLIRVHDVLETKSVLDVLTKIDQVKDPNSSSVDKLAAALE 6k4r A 3.109 BS01 AMP A 1 R352 K367 N534 R536 D542 D545 R254 K269 N420 R422 D428 D431 6.-.-.- 0000166,0006508,0008234,0016740,0016874,0046872 -logKd/Ki=5.84, Kd=1.45uM Q5ZTK6 31330531 901 VKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWR 6k4r B 3.109 BS01 AMP B 1 R352 K367 Q486 N534 D542 R253 K268 Q387 N427 D435 6.-.-.- 0000166,0006508,0008234,0016740,0016874,0046872 Q5ZTK6 31330531 901 KQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFW 6k5l A 2.55 BS01 AMP A 1 N104 S105 H113 L116 K291 K294 T295 Y298 F375 N377 N104 S105 H113 L116 K291 K294 T295 Y298 F375 N377 2.7.11.5,3.1.3.- 0000287,0004674,0004721,0004722,0005515,0005524,0005737,0006006,0006097,0006099,0008772,0016208,0016310,0016788,0016791,0030145 P11071 31235769 1001 MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYG 6k5l B 2.55 BS01 AMP B 1 N104 S105 H113 L116 K291 K294 T295 Y298 F375 N377 N96 S97 H105 L108 K283 K286 T287 Y290 F367 N369 2.7.11.5,3.1.3.- 0000287,0004674,0004721,0004722,0005515,0005524,0005737,0006006,0006097,0006099,0008772,0016208,0016310,0016788,0016791,0030145 P11071 31235769 1001 GLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITDAEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYG 6k8k A 2.5 BS02 AMP A 1 L293 N356 R357 V360 L395 Y399 L290 N345 R346 V349 L384 Y388 G290 L293 W321 N356 W374 W397 G287 L290 W310 N345 W363 W386 ? 0000325,0005515,0005524,0005634,0005737,0006139,0006325,0006338,0006950,0006952,0007623,0009414,0009416,0009637,0009638,0009646,0009785,0009881,0009882,0009909,0009911,0010075,0010118,0010244,0010617,0016301,0016604,0016605,0042752,0042802,0042803,0046777,0046872,0048574,0051607,0071949,0072387,0097159,1901371,1902347,2000028,2000379 Q96524 32398826 702 DKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIQTHNTISAILDCIRVTGPTKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFGVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMI 6k8k B 2.5 BS02 AMP B 1 L293 N356 R357 L395 Y399 L287 N343 R344 L382 Y386 G290 L293 W321 N356 W374 W397 G284 L287 W308 N343 W361 W384 ? 0000325,0005515,0005524,0005634,0005737,0006139,0006325,0006338,0006950,0006952,0007623,0009414,0009416,0009637,0009638,0009646,0009785,0009881,0009882,0009909,0009911,0010075,0010118,0010244,0010617,0016301,0016604,0016605,0042752,0042802,0042803,0046777,0046872,0048574,0051607,0071949,0072387,0097159,1901371,1902347,2000028,2000379 Q96524 32398826 702 DKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIQTHNTISAILDCIRVTGPTKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFGVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIM 6k8k D 2.5 BS02 AMP D 1 R289 L293 N356 R357 L395 Y399 D406 R286 L290 N347 R348 L386 Y390 D397 G290 L293 W321 N356 W374 W397 G287 L290 W312 N347 W365 W388 ? 0000325,0005515,0005524,0005634,0005737,0006139,0006325,0006338,0006950,0006952,0007623,0009414,0009416,0009637,0009638,0009646,0009785,0009881,0009882,0009909,0009911,0010075,0010118,0010244,0010617,0016301,0016604,0016605,0042752,0042802,0042803,0046777,0046872,0048574,0051607,0071949,0072387,0097159,1901371,1902347,2000028,2000379 Q96524 32398826 702 MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIQTHNTISAILDCIRVTGPTKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFGVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMI 6k8k G 2.5 BS02 AMP G 1 K237 L293 N356 L395 Y399 I404 K237 L293 N351 L390 Y394 I399 G290 L293 W321 N356 W374 W397 G290 L293 W316 N351 W369 W392 ? 0000325,0005515,0005524,0005634,0005737,0006139,0006325,0006338,0006950,0006952,0007623,0009414,0009416,0009637,0009638,0009646,0009785,0009881,0009882,0009909,0009911,0010075,0010118,0010244,0010617,0016301,0016604,0016605,0042752,0042802,0042803,0046777,0046872,0048574,0051607,0071949,0072387,0097159,1901371,1902347,2000028,2000379 Q96524 32398826 702 MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIQTHNTISAILDCIRVTGPTKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFGVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMI 6kby A 1.097 BS01 AMP A 1 S64 F119 Y149 N151 Y221 G316 S317 T318 S66 F121 Y151 N153 Y223 G315 S316 T317 S64 K67 Y149 E273 K314 S317 S66 K69 Y151 E272 K313 S316 3.5.2.6 0000166,0008800,0016787,0017001,0030288,0046677 Q9XB24 31451494 401 HHANIDESKIKDTVDDLIQPLMQKNNIPGMSVAVTVNGKNYIYNYGLAAKQPQQPVTENTLFEVGSLSKTFAATLASYAQVSGKLSLDQSVSHYVPELRGSSFDHVSVLNVGTHTSGLQLFMPEDIKNTTQLMAYLKAWKPADAAGTHRVYSNIGTGLLGMIAAKSLGVSYEDAIEKTLLPQLGMHHSYLKVPADQMENYAWGYNKKDEPVHVNMEILGNEAYGIKTTSSDLLRYVQANMGQLKLAKMQQALTATHTGYFKSGEITQDLMWEQLPYPVSLPNLLTGNDMAMTKSVATPIVPPLPPQENVWINKTGSTNGFGAYIAFVPAKKMGIVMLANKNYSIDQRVTVAYKILSSLEGNK 6kdu A 2.2 BS01 AMP A 1 S91 L92 K123 R144 H236 K300 K324 S84 L85 K116 R137 H229 K293 K317 6.5.1.2 0003911 P9WNV1 34076591 401 QTAPEVLRQWQALAAEVREHQFRYYVRDAPIISDAEFDELLRRLEALEEQHPELRTPDSPTQLVGGAGFATDFEPVDHLERMLSLDNAFTADELAAWAGRIHAEVGDAAHYLCELKIDGVALSLVYREGRLTRASTRGDGRTGEDVTLNARTIADVPERLTPGDDYPVPEVLEVRGEVFFRLDDFQALNASLVEEGKAPFANPRNSAAGSLRQKDPAVTARRRLRMICHGLGHVEGFRPATLHQAYLALRAWGLPVSEHTTLATDLAGVRERIDYWGEHRHEVDHEIDGVVVKVDEVALQRRLGSTSRAPRWAIAYKYPPE 6kjm A 2.2 BS02 AMP A 1 E121 K123 I124 E184 H236 K300 E114 K116 I117 E177 H229 K293 6.5.1.2 0003911 P9WNV1 33197566 402 QTAPEVLRQWQALAEEVREHQFRYYVRDAPIISDAEFDELLRRLEALEEQHPELRTPDSPTQLVGGAGFATDFEPVDHLERMLSLDNAFTADELAAWAGRIHAEVGDAAHYLCELKIDGVALSLVYREGRLTRASTRGDGRTGEDVTLNARTIADVPERLTPGDDYPVPEVLEVRGEVFFRLDDFQALNASLVEEGKAPFANPRNSAAGSLRQKDPAVTARRRLRMICHGLGHVEGFRPATLHQAYLALRAWGLPVSEHTTLATDLAGVRERIDYWGEHRHEVDHEIDGVVVKVDEVALQRRLGSTSRAPRWAIAYKYPPE 6krh A 2.6 BS01 AMP A 1 L92 N94 K123 I124 Y236 V298 K324 L85 N87 K116 I117 Y229 V291 K317 6.5.1.2 0003911 P9WNV1 34076591 401 QTAPEVLRQWQALAEEVREHQFRYYVRDAPIISDAEFDELLRRLEALEEQHPELRTPDSPTQLVGGAGFATDFEPVDHLERMLSLDNAFTADELAAWAGRIHAEVGDAAHYLCELKIDGVALSLVYREGRLTRASTRGDGRTGEDVTLNARTIADVPERLTPGDDYPVPEVLEVRGEVFFRLDDFQALNASLVEEGKAPFANPRNSAAGSLRQKDPAVTARRRLRMICYGLGHVEGFRPATLHQAYLALRAWGLPVSEHTTLATDLAGVRERIDYWGEHRHEVDHEIDGVVVKVDEVALQRRLGSTSRAPRWAIAYKYPPE 6ksc A 2.4 BS01 AMP A 1 E121 L122 R123 R144 E184 H236 K300 E114 L115 R116 R137 E177 H229 K293 6.5.1.2 0003911 P9WNV1 34076591 401 QTAPEVLRQWQALAEEVREHQFRYYVRDAPIISDAEFDELLRRLEALEEQHPELRTPDSPTQLVGGAGFATDFEPVDHLERMLSLDNAFTADELAAWAGRIHAEVGDAAHYLCELRIDGVALSLVYREGRLTRASTRGDGRTGEDVTLNARTIADVPERLTPGDDYPVPEVLEVRGEVFFRLDDFQALNASLVEEGKAPFANPRNSAAGSLRQKDPAVTARRRLRMICHGLGHVEGFRPATLHQAYLALRAWGLPVSEHTTLATDLAGVRERIDYWGEHRHEVDHEIDGVVVKVDEVALQRRLGSTSRAPRWAIAYKYPPE 6l5m A 2.7 BS01 AMP A 1 V206 F210 Q213 G233 G235 K236 T237 V19 F23 Q26 G46 G48 K49 T50 3.6.4.13 0003676,0003724,0005524 Q9NR30 32714761 601 FSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLTVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQVEQKAGIKFKRI 6l5m B 2.7 BS01 AMP B 1 V206 F210 Q213 G233 G235 K236 T237 V19 F23 Q26 G46 G48 K49 T50 3.6.4.13 0003676,0003724,0005524 Q9NR30 32714761 601 FSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLTVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQVEQKAGIKFKRI 6l5m C 2.7 BS01 AMP C 1 V206 F210 Q213 G233 G235 K236 T237 V19 F23 Q26 G46 G48 K49 T50 3.6.4.13 0003676,0003724,0005524 Q9NR30 32714761 601 FSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLTVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQVEQKAGIKFKRI 6l5m D 2.7 BS01 AMP D 1 V206 F210 Q213 G233 G235 K236 T237 V19 F23 Q26 G46 G48 K49 T50 3.6.4.13 0003676,0003724,0005524 Q9NR30 32714761 601 FSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLTVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQVEQKAGIKFKRI 6l5m E 2.7 BS01 AMP E 1 V206 F210 Q213 G233 G235 K236 T237 V19 F23 Q26 G46 G48 K49 T50 3.6.4.13 0003676,0003724,0005524 Q9NR30 32714761 601 FSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLTVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQVEQKAGIKFKRI 6ldk A 2.9 BS01 AMP A 1 F55 H61 G63 H64 E568 G569 D571 I601 V602 F41 H47 G49 H50 E553 G554 D556 I586 V587 P53 D92 W536 Q572 W576 K609 K612 P39 D78 W521 Q557 W561 K594 K597 6.1.1.5 0000049,0000166,0002161,0004812,0004822,0005524,0006418,0006428 Q59RI1 32088946 901 FSFPKEEEAVIKHWDDVNAFQRTLELTEDLPPFAFFDGPPFATGTPHYGHILASTVKDIIPRYATMNGYHVERRFGWDTHGLPVEHEIDKKLNITSKEDVYAMGIDKYNAECRAIVMRYADEWRRTIKRLGRWIDMDNDYKTLYPEFMESVWWAFKELFNKDAVYRGLRVMPYSTACTTPLSNFEAQQNYKEVNDPALTISFPLLDNEDTCLVAWTTTPWTLPANLALAVNPKFEYVKIFDEEKKKNFILLESLISTLYKKPKSAKFKVVEKILGKDLVGLKYKPLFNYFYEDFKDTGFRVIPADYVTNDSGTGIVHQAPSYGEEDFNSTKAAGVINKKLPPSIVDDSGRMESNVPEIAGMYFKDADKVIIKKLSEEGRLLVNTQVKHSYPFCWRSDTPLMYRTVPAWFVRIGEVIPEMLDNVEKTNWVPSNIKDKRFSNWIANARDWNISRNRYWGTPIPLWVSDDFEEMVCVGSIQELRELSGRDDITDIHRESIDSITIPSKKGKGQLKRIEEVFDCWFESGSMPYASKHYPFENEKKFLDAFPANFISEGLDQTRGWFYTLTVLGTHLFKTAPYQNVIVTGIVLAADGKKMSKRLKNYPDPTLVLEKYGADALRLYLINSPVLRAETLKFKEEGVKEIVSSVLLPWYNSYKFLKDAADLFKKDNGKDFVYDNSLHSTNVMDRWLLASIQSLIKFIHEEMTGYRLYTVVPRLLHFIDDLTNWYIRFNRRRIKGYASEDVEDTQKGLNTLVEALLTLSRAMAPFTPYLADGIYQRIKVYFKQEDLEKIAINPKNVDLRSVHFLSYPSVRQE 6ln3 A 2.0 BS01 AMP A 1 F41 G42 M45 R58 R62 Q73 T98 H99 G111 R145 F41 G42 M45 R58 R62 Q73 T98 H99 G111 R145 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0016887,0046940 Q9YDD2 32271910 301 MRHPFKVVVVTGVPGVGKTTVIKELQGLAEKEGVKLHIVNFGSFMLDTAVKLGLVEDRDKIRTLPLRRQLELQREAAKRIVAEASKALGGDGVLIIDTHALVKTVAGYWPGLPKHVLDELKPDMIAVVEASPEEVAARQARDTTRYRVDIGGVEGVKRLMENARAASIASAIQYASTVAIVENREGEAAKAAEELLRLIKNL 6lp0 A 1.519 BS01 AMP A 1 Y93 I94 G132 Y134 I178 E183 R186 N213 Y70 I71 G109 Y111 I155 E160 R163 N190 3.2.2.22 0017148,0030598 P16094 32653369 301 DVSFRLSGADPRSYGMFIKDLRNALPFREKVYNIPLLLPSVSGAGRYLLMHLFNYDGKTITVAVDVTNVYIMGYLADTTSYFFNEPAAELASQYVFRDARRKITLPYSGNYERLQIAAGKPREKIPIGLPALDSAISTLLHYDSTAAAGALLVLIQTTAEAARFKYIEQQIQERAYRDEVPSLATISLENSWSGLSKQIQLAQGNNGIFRTPIVLVDNKGNRVQITNVTSKVVTSNIQLLLNTRN 6ls5 A 2.031 BS01 AMP A 1 V17 E20 G21 A24 G26 T27 G28 E29 L30 Y113 M177 V9 E12 G13 A16 G18 T19 G20 E21 L22 Y105 M169 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 32375478 402 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 6ls5 B 2.031 BS02 AMP B 1 V17 E20 G21 A24 G26 T27 E29 L30 K112 Y113 M177 V9 E12 G13 A16 G18 T19 E21 L22 K100 Y101 M165 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 32375478 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 6ls5 C 2.031 BS01 AMP C 1 V17 E20 G21 A24 G26 T27 E29 L30 K112 Y113 V160 M177 V9 E12 G13 A16 G18 T19 E21 L22 K97 Y98 V145 M162 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 32375478 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 6ls5 D 2.031 BS01 AMP D 1 V17 E20 G21 T27 G28 E29 L30 K112 Y113 R140 M177 V9 E12 G13 T19 G20 E21 L22 K104 Y105 R132 M169 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 32375478 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 6ltc A 3.3 BS01 AMP A 1 G761 D762 P787 T788 Y811 D876 I888 G712 D713 P738 T739 Y762 D827 I839 T642 L662 T788 E789 R902 K982 T597 L613 T739 E740 R849 K889 ? 0000036,0000166,0003824,0005737,0006633,0008610,0017000,0031177,0043041,0044550 A0A077JG85 33783097 1201 AAELPPLVPEPGDAGQPFPLTPTQQALWVGRAGCYGYFEWERPELDLARYRRAWERLVAHHPGLRTVVRPDGTQHVLERPGPVPITVEDLRQDPDAVRRLEESRLDPGTWPMFDLRVVLLSGRVRVQLGIDLQLMDASSLFLNLFSDLVTLYDDPDAALASQKLAFRDFARWLEEDVRGGARWRADWAYWQERLDGLPPAPDLPAARKFERCMVRCPAEEFALLRERALAHGLTETELLVGAFAEVLRGWSSDPAFTLNVPVFQRFDVPGIEDVIGDYTNPILLEARPEGRTVAERIVALAARLRADTRHASVNGVEVLRELARRRGLAAAAMPVVVTSLLGLPSAARSITEFGTEVHSITQTPQVSLDFQIRPEDGELRLVWDHRSGAFAPGVVEGAFEAFLDLVGRMLADEPGHGVWEAPFADMRSRRDRAVWNETNDTAEPVPAVLLQERFFAQARRTPDAEAVVASGLRLTYDELARHAYRIGNTLRERGVRPGDLVGVVMEKGWEQYAAVYGILAAGGAYLPIDAASPRGRVARLLESAGAGIVLTQSRLRDELDLPAGTTVLRADTDFETASTAPLTPVQGPDDPAYVIYTGEPKGVVVAHRGVANLVRDVRRRFAVTPADRLLALSGLHFDASVYDVFGPLACGATVVVPPPFRRAEPDVWAELVRDERVTFWNSVPVLLELLVGEAESRDDRPLATLRLAVVSGDWIPLDLPGRARAQAPGLRVVGSGGPTETICWSLFHPIDAVDPQWTSIPYGKPIANQRYYIVDRDLRPRPTWARGEMAVASPLGLALGYLNDPERTAAKFVTLPGTGERAYLTGDFGRLLPDGGIEILGREDFQGQRIELGEIGVRAAVADVVLREHLSAELAIRLLPELPLTANGKVDRLALA 6ltd A 4.1 BS01 AMP A 1 G761 D762 G786 P787 T788 D876 I888 R891 G710 D711 G735 P736 T737 D825 I837 R840 T642 L662 T788 E789 R902 K982 T595 L611 T737 E738 R847 K876 ? 0000036,0000166,0003824,0005737,0006633,0008610,0017000,0031177,0043041,0044550 A0A077JG85 33783097 1201 AAELPPLVPEPGDAGQPFPLTPTQQALWVGRAYGYFEWERPELDLARYRRAWERLVAHHPGLRTVVRPDGTQHVLERPGPVPITVEDLRQDPDAVRRLEESRLDPGTWPMFDLRVVLLSGRVRVQLGIDLQLMDASSLFLNLFSDLVTLYDDPDAALASQKLAFRDFARWLEEDVRGGARWRADWAYWQERLDGLPPAPDLPAARKFERCMVRCPAEEFALLRERALAHGLTETELLVGAFAEVLRGWSSDPAFTLNVPVFQRFDVPGIEDVIGDYTNPILLEARPEGRTVAERIVALAARLRADTRHASVNGVEVLRELARRRGLAAAAMPVVVTSLLGLPSAARSITEFGTEVHSITQTPQVSLDFQIRPEDGELRLVWDHRSGAFAPGVVEGAFEAFLDLVGRMLADEPGHGVWEAPFADMRSRRDRAVWNETNDTAEPVPAVLLQERFFAQARRTPDAEAVVASGLRLTYDELARHAYRIGNTLRERGVRPGDLVGVVMEKGWEQYAAVYGILAAGGAYLPIDAASPRGRVARLLESAGAGIVLTQSRLRDELDLPAGTTVLRADTDFETASTAPLTPVQGPDDPAYVIYTGEPKGVVVAHRGVANLVRDVRRRFAVTPADRLLALSGLHFDASVYDVFGPLACGATVVVPPPFRRAEPDVWAELVRDERVTFWNSVPVLLELLVGEAESRDDRPLATLRLAVVSGDWIPLDLPGRARAQAPGLRVVGSGGPTETICWSLFHPIDAVDPQWTSIPYGKPIANQRYYIVDRDLRPRPTWARGEMAVASPLGLALGYLNDPERTAAKFVTLPGTGERAYLTGDFGRLLPDGGIEILGREDFQGQRIELGEIGVRAAADVVRRLLPELPLTANGKVDRLALA 6ltd B 4.1 BS01 AMP B 1 G761 D762 P787 T788 E789 D876 I888 R891 G711 D712 P737 T738 E739 D826 I838 R841 T642 L662 T788 E789 R902 K982 T596 L612 T738 E739 R846 K875 ? 0000036,0000166,0003824,0005737,0006633,0008610,0017000,0031177,0043041,0044550 A0A077JG85 33783097 1201 AAELPPLVPEPGDAGQPFPLTPTQQALWVGRACYGYFEWERPELDLARYRRAWERLVAHHPGLRTVVRPDGTQHVLERPGPVPITVEDLRQDPDAVRRLEESRLDPGTWPMFDLRVVLLSGRVRVQLGIDLQLMDASSLFLNLFSDLVTLYDDPDAALASQKLAFRDFARWLEEDVRGGARWRADWAYWQERLDGLPPAPDLPAARKFERCMVRCPAEEFALLRERALAHGLTETELLVGAFAEVLRGWSSDPAFTLNVPVFQRFDVPGIEDVIGDYTNPILLEARPEGRTVAERIVALAARLRADTRHASVNGVEVLRELARRRGLAAAAMPVVVTSLLGLPSAARSITEFGTEVHSITQTPQVSLDFQIRPEDGELRLVWDHRSGAFAPGVVEGAFEAFLDLVGRMLADEPGHGVWEAPFADMRSRRDRAVWNETNDTAEPVPAVLLQERFFAQARRTPDAEAVVASGLRLTYDELARHAYRIGNTLRERGVRPGDLVGVVMEKGWEQYAAVYGILAAGGAYLPIDAASPRGRVARLLESAGAGIVLTQSRLRDELDLPAGTTVLRADTDFETASTAPLTPVQGPDDPAYVIYTGEPKGVVVAHRGVANLVRDVRRRFAVTPADRLLALSGLHFDASVYDVFGPLACGATVVVPPPFRRAEPDVWAELVRDERVTFWNSVPVLLELLVGEAESRDDRPLATLRLAVVSGDWIPLDLPGRARAQAPGLRVVGSGGPTETICWSLFHPIDAVDPQWTSIPYGKPIANQRYYIVDRDLRPRPTWARGEMAVASPLGLALGYLNDPERTAAKFVTLPGTGERAYLTGDFGRLLPDGGIEILGREDFQRIELGEIGVRAAADVVIRLLPELPLTANGKVDRLALA 6m2t A 2.14 BS01 AMP A 1 G303 E304 A305 G325 I326 S328 T329 D406 R421 K427 Y432 G298 E299 A300 G320 I321 S323 T324 D401 R416 K422 Y427 S181 T201 T329 E330 K427 Y432 K512 S176 T196 T324 E325 K422 Y427 K507 ? 0000166,0005524,0016405,0016874,0016878,0044550 Q93TK0 601 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLAAFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVL 6m2t B 2.14 BS01 AMP B 1 G303 E304 A305 G325 I326 G327 S328 T329 D406 R421 K427 Y432 G298 E299 A300 G320 I321 G322 S323 T324 D401 R416 K422 Y427 S181 T201 T329 E330 K427 Y432 K512 S176 T196 T324 E325 K422 Y427 K507 ? 0000166,0005524,0016405,0016874,0016878,0044550 Q93TK0 601 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLAAFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVL 6m2t C 2.14 BS01 AMP C 1 G303 E304 A305 G325 I326 S328 T329 D406 R421 K427 Y432 G298 E299 A300 G320 I321 S323 T324 D401 R416 K422 Y427 S181 T201 T329 E330 K427 Y432 K512 S176 T196 T324 E325 K422 Y427 K507 ? 0000166,0005524,0016405,0016874,0016878,0044550 Q93TK0 601 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLAAFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVL 6m2t D 2.14 BS01 AMP D 1 G303 E304 A305 G325 I326 S328 T329 D406 R421 K427 Y432 G298 E299 A300 G320 I321 S323 T324 D401 R416 K422 Y427 S181 T201 T329 E330 K427 Y432 K512 S176 T196 T324 E325 K422 Y427 K507 ? 0000166,0005524,0016405,0016874,0016878,0044550 Q93TK0 601 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLAAFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVL 6m2u A 1.709 BS01 AMP A 1 G303 E304 A305 D324 G325 I326 G327 T329 D406 R421 K427 Y432 G298 E299 A300 D319 G320 I321 G322 T324 D401 R416 K422 Y427 S181 T201 T329 E330 K427 Y432 K512 S176 T196 T324 E325 K422 Y427 K507 ? 0000166,0005524,0016405,0016874,0016878,0044550 Q93TK0 32397467 601 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLAAFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVL 6m2u B 1.709 BS01 AMP B 1 G303 E304 A305 D324 G325 I326 S328 T329 D406 R421 K427 Y432 G298 E299 A300 D319 G320 I321 S323 T324 D401 R416 K422 Y427 S181 T201 T329 E330 K427 Y432 K512 S176 T196 T324 E325 K422 Y427 K507 ? 0000166,0005524,0016405,0016874,0016878,0044550 Q93TK0 32397467 601 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLAAFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVL 6m79 A 3.1 BS01 AMP A 1 N356 Y399 D406 N332 Y375 D382 G290 L293 W321 N356 W374 W397 G280 L283 W297 N332 W350 W373 ? 0000325,0005515,0005524,0005634,0005737,0006139,0006325,0006338,0006950,0006952,0007623,0009414,0009416,0009637,0009638,0009646,0009785,0009881,0009882,0009909,0009911,0010075,0010118,0010244,0010617,0016301,0016604,0016605,0042752,0042802,0042803,0046777,0046872,0048574,0051607,0071949,0072387,0097159,1901371,1902347,2000028,2000379 Q96524 33199893 701 KKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIQTHNTISAILDCIRVTGPTKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPIIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFGVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKA 6m79 B 3.1 BS01 AMP B 1 N356 Y399 D406 N329 Y372 D379 G290 L293 W321 N356 W374 W397 G277 L280 W294 N329 W347 W370 ? 0000325,0005515,0005524,0005634,0005737,0006139,0006325,0006338,0006950,0006952,0007623,0009414,0009416,0009637,0009638,0009646,0009785,0009881,0009882,0009909,0009911,0010075,0010118,0010244,0010617,0016301,0016604,0016605,0042752,0042802,0042803,0046777,0046872,0048574,0051607,0071949,0072387,0097159,1901371,1902347,2000028,2000379 Q96524 33199893 701 KKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIQTHNTISAILDCIRVTGPTKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPIIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFGVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRT 6m79 C 3.1 BS01 AMP C 1 N356 Y399 D406 N332 Y375 D382 G290 L293 W321 N356 W374 W397 G280 L283 W297 N332 W350 W373 ? 0000325,0005515,0005524,0005634,0005737,0006139,0006325,0006338,0006950,0006952,0007623,0009414,0009416,0009637,0009638,0009646,0009785,0009881,0009882,0009909,0009911,0010075,0010118,0010244,0010617,0016301,0016604,0016605,0042752,0042802,0042803,0046777,0046872,0048574,0051607,0071949,0072387,0097159,1901371,1902347,2000028,2000379 Q96524 33199893 701 KKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIQTHNTISAILDCIRVTGPTKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPIIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFGVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKA 6m79 D 3.1 BS01 AMP D 1 N356 Y399 D406 N329 Y372 D379 G290 L293 W321 N356 W374 W397 G277 L280 W294 N329 W347 W370 ? 0000325,0005515,0005524,0005634,0005737,0006139,0006325,0006338,0006950,0006952,0007623,0009414,0009416,0009637,0009638,0009646,0009785,0009881,0009882,0009909,0009911,0010075,0010118,0010244,0010617,0016301,0016604,0016605,0042752,0042802,0042803,0046777,0046872,0048574,0051607,0071949,0072387,0097159,1901371,1902347,2000028,2000379 Q96524 33199893 701 KKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIQTHNTISAILDCIRVTGPTKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPIIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFGVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRT 6mmo A 1.86 BS03 AMP B 1 G30 Y31 T32 L64 G31 Y32 T33 L52 ? 0005524,0006808,0030234,0046872 -logKd/Ki=3.35, Kd=447uM B5II98 201 SSQQVWKLVIITEEILLKKVSKIIKEAGASGYTVLAAAGEGSAYSNIKFEVLTASRELADQIQDKVVAKYFDDYSCITYISTVEALRAHKF 6mmo A 1.86 BS04 AMP D 1 G38 E39 G40 S41 N58 S87 I89 G39 E40 G41 S42 N46 S75 I77 ? 0005524,0006808,0030234,0046872 -logKd/Ki=3.35, Kd=447uM B5II98 201 SSQQVWKLVIITEEILLKKVSKIIKEAGASGYTVLAAAGEGSAYSNIKFEVLTASRELADQIQDKVVAKYFDDYSCITYISTVEALRAHKF 6mmo B 1.86 BS02 AMP B 1 G38 E39 G40 S41 N58 S87 I89 G38 E39 G40 S41 N45 S74 I76 ? 0005524,0006808,0030234,0046872 -logKd/Ki=3.35, Kd=447uM B5II98 201 SQQVWKLVIITEEILLKKVSKIIKEAGASGYTVLAAAGEGSAYSNIKFEVLTASRELADQIQDKVVAKYFDDYSCITYISTVEA 6mmo B 1.86 BS04 AMP D 2 G30 Y31 T32 L64 G30 Y31 T32 L51 ? 0005524,0006808,0030234,0046872 -logKd/Ki=3.35, Kd=447uM B5II98 202 SQQVWKLVIITEEILLKKVSKIIKEAGASGYTVLAAAGEGSAYSNIKFEVLTASRELADQIQDKVVAKYFDDYSCITYISTVEA 6mmo C 1.86 BS01 AMP C 1 G30 Y31 T32 L64 G30 Y31 T32 L51 ? 0005524,0006808,0030234,0046872 B5II98 201 SQQVWKLVIITEEILLKKVSKIIKEAGASGYTVLAAAGEGSRYSNIKFEVLTASRELADQIQDKVVAKYFDDYSCITYISTVEALRA 6mmo C 1.86 BS02 AMP F 1 G38 E39 G40 S41 R42 S87 I89 G38 E39 G40 S41 R42 S74 I76 ? 0005524,0006808,0030234,0046872 B5II98 201 SQQVWKLVIITEEILLKKVSKIIKEAGASGYTVLAAAGEGSRYSNIKFEVLTASRELADQIQDKVVAKYFDDYSCITYISTVEALRA 6mmo D 1.86 BS01 AMP D 1 G30 Y31 T32 V63 L64 G30 Y31 T32 V50 L51 ? 0005524,0006808,0030234,0046872 B5II98 201 SQQVWKLVIITEEILLKKVSKIIKEAGASGYTVLAAAGEGSRYSNIKFEVLTASRELADQIQDKVVAKYFDDYSCITYISTVEALR 6mmo D 1.86 BS02 AMP D 2 G38 E39 G40 S41 R42 S87 I89 G38 E39 G40 S41 R42 S74 I76 ? 0005524,0006808,0030234,0046872 B5II98 202 SQQVWKLVIITEEILLKKVSKIIKEAGASGYTVLAAAGEGSRYSNIKFEVLTASRELADQIQDKVVAKYFDDYSCITYISTVEALR 6mmo E 1.86 BS01 AMP C 1 G38 E39 G40 R42 N58 S87 I89 G39 E40 G41 R43 N47 S76 I78 ? 0005524,0006808,0030234,0046872 B5II98 201 SSQQVWKLVIITEEILLKKVSKIIKEAGASGYTVLAAAGEGSRAYSNIKFEVLTASRELADQIQDKVVAKYFDDYSCITYISTVEALRA 6mmo E 1.86 BS02 AMP E 1 S29 G30 Y31 T32 V63 L64 S30 G31 Y32 T33 V52 L53 ? 0005524,0006808,0030234,0046872 B5II98 301 SSQQVWKLVIITEEILLKKVSKIIKEAGASGYTVLAAAGEGSRAYSNIKFEVLTASRELADQIQDKVVAKYFDDYSCITYISTVEALRA 6mmo F 1.86 BS01 AMP E 1 G38 E39 G40 S41 N58 S87 I89 G38 E39 G40 S41 N45 S74 I76 ? 0005524,0006808,0030234,0046872 B5II98 301 SQQVWKLVIITEEILLKKVSKIIKEAGASGYTVLAAAGEGSAYSNIKFEVLTASRELADQIQDKVVAKYFDDYSCITYISTVEALRA 6mmo F 1.86 BS02 AMP F 1 G30 Y31 T32 L64 G30 Y31 T32 L51 ? 0005524,0006808,0030234,0046872 B5II98 201 SQQVWKLVIITEEILLKKVSKIIKEAGASGYTVLAAAGEGSAYSNIKFEVLTASRELADQIQDKVVAKYFDDYSCITYISTVEALRA 6mn8 A 2.35 BS04 AMP A 1 R190 E192 T202 F205 Q275 A277 T278 S313 R315 R138 E140 T150 F153 Q216 A218 T219 S254 R256 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433,0017101,0046872 A0A2K6VKP7 605 AHHHHHHIEISKDENYSEWYVQVITKAEMIEYYDISGCYVLRPWSYAIWEFIQEWFDEEIKKLGVKNCYFPLFVSQSALEKEFAPEVAWITRAGQSDLAEAIAIRPTSETVMYPSYAKWVQSHRDLPIKLNQWCNVVRWEFKHPTPFLRTREFLWQEGHTAFQSKDEAEDEVFKILDLYAQIYIDLLAIPVIKGRKGGDFTATVEAYVPVNGRGIQGATSHHLGQNFSKMFNISFEDPNGGGKIYAWQNSWGISTRTIGALVMIHGDNCGLVLPPRVATIQMIIVPVGITKDEQKTALIEKAKEINNKLMDASIRAELDIRDHISPGWKFNHWELKGVPVRIEIGPKDLANNQVTCVIRYSGEKRTIPIDGLASKCKDMLEEIHYSMYNRILEVRESHT 6mv7 A 2.59 BS01 AMP A 1 K7 C62 N64 R66 N68 A105 H122 K8 C63 N65 R67 N69 A106 H123 H15 K38 H122 L123 D124 H16 K39 H123 L124 D125 3.1.27.- 0003676,0004519,0004540,0005576,0005615,0005764,0006401,0006952,0019731,0031410,0042742,0045087,0050829,0050830,0051607,0061844 Q93091 31909602 201 MWPKRLTKAHWFEIQHIQPSPLQCNRAMSGINNYTQHCKHQNTFLHDSFQNVAAVCDLLSIVCKNRRHNCHQSSKPVNMTDCRLTSGKYPQCRYSAAAQYKFFIVACDPPQKSDPPYKLVPVHLDSIL 6nab A 2.0 BS01 AMP A 1 E144 I152 R153 S154 F157 Q227 T230 G262 S264 R266 E141 I149 R150 S151 F154 Q224 T227 G259 S261 R263 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433,0017101 A0A4V8H034 601 EGIDVKKQENFSEWYSQVITKSEFLDYYDVSGCYIFRPNCWFVWESVQKFFDAEIKKLGVQNVMFPLFVTKRALETEKDHVEGFSPEVAWVTKSGNSDLQEPIALRPTSETIMYPSYAKWIQSHRDLPLKLNQWTNVVRWEFKHAVPFIRSREFYWQEGHSAFKSKEEADEEVFTILELYKRVYEELLAVPVIKGTKTENEKFAGADYTTTVETFIATNGRAVQGGTSHHLGQNFSKMFKIQFEAENKETQFAYQNSWGLSTRTLGVMIMVHGDDKGMVLPPRVAFCQVVVIPLIDNATLVEKTKEIYNELEKAGIRVKLDDRRTPGWKYNYWELRGVPLRIEVGPKDLEKQQIMLCRRDTGEKWTMPLSEFSGDSIKAVLDKIHDSMLNKARKEMNERIVVTRTWPEFIKALNSGNMCLIPWHESKAAEEYIKEKSKLESVQSQSDANTGLTGAAKSLCVPLDQSSFPSLEGLENFYPEEAHKKPNCWALFGRSY 6nab B 2.0 BS01 AMP B 1 R142 E144 I152 S154 F157 Q227 T230 G262 S264 R266 R139 E141 I149 S151 F154 Q224 T227 G259 S261 R263 6.1.1.15 0000166,0004812,0004827,0005524,0005737,0006418,0006433,0017101 A0A4V8H034 601 EGIDVKKQENFSEWYSQVITKSEFLDYYDVSGCYIFRPNCWFVWESVQKFFDAEIKKLGVQNVMFPLFVTKRALETEKDHVEGFSPEVAWVTKSGNSDLQEPIALRPTSETIMYPSYAKWIQSHRDLPLKLNQWTNVVRWEFKHAVPFIRSREFYWQEGHSAFKSKEEADEEVFTILELYKRVYEELLAVPVIKGTKTENEKFAGADYTTTVETFIATNGRAVQGGTSHHLGQNFSKMFKIQFEAENKETQFAYQNSWGLSTRTLGVMIMVHGDDKGMVLPPRVAFCQVVVIPLINATLVEKTKEIYNELEKAGIRVKLDDRLERTPGWKYNYWELRGVPLRIEVGPKDLEKQQIMLCRRDTGEKWTMPLSEFSGDSIKAVLDKIHDSMLNKARKEMNERIVVTRTWPEFIKALNSGNMCLIPWHESKAAEEYIKEKSKLESVQSQSDANTGLTGAAKSLCVPLDQSSFPSLEGLENFYPEEAHKKPNCWALFGRSY 6nbj A 2.94 BS03 AMP A 1 S172 G173 G199 D203 A217 R218 G325 V326 S328 N329 M356 S360 S143 G144 G170 D174 A188 R189 G296 V297 S299 N300 M327 S331 2.3.1.234 0000049,0002949,0005739,0005759,0006400,0008033,0008252,0008270,0016746,0016747,0046872,0061711,0070525,0072670 P43122 502 RKGYKVLAIETSCDDTCVSVLDRFSKSAAPNVLANLKDTLDSIDEGGIIPTKAHIHHQARIGPLTERALIESNAREGIDLICVTRGPGMPGSLSGGLDFAKGLAVAWNKPLIGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFVLSRAIDDHEILCDTIDIAVGDSLDKCGRELGFKGTMIAREMEKFINQDINDQDFALKLEMPSPLKNSASKRNMLSFSFSAFITALRTNLTKLGKTEIQELPEREIRSIAYQVQESVFDHIINKLKHVLKSQPEKFKNVREFVCSGGVSSNQRLRTKLETELGTLNSTSFFNFYYPPMDLCSDNSIMIGWAGIEIWESLRLVSDLDICPIRQWPLNDLLSVDGWRTDQL 6nbj B 2.94 BS04 AMP B 1 D203 A217 R218 G325 N329 S360 D174 A188 R189 G296 N300 S331 2.3.1.234 0000049,0002949,0005739,0005759,0006400,0008033,0008252,0008270,0016746,0016747,0046872,0061711,0070525,0072670 P43122 502 RKGYKVLAIETSCDDTCVSVLDRFSKSAAPNVLANLKDTLDSIDEGGIIPTKAHIHHQARIGPLTERALIESNAREGIDLICVTRGPGMPGSLSGGLDFAKGLAVAWNKPLIGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFVLSRAIDDHEILCDTIDIAVGDSLDKCGRELGFKGTMIAREMEKFINQDINDQDFALKLEMPSPLKNSASKRNMLSFSFSAFITALRTNLTKLGKTEIQELPEREIRSIAYQVQESVFDHIINKLKHVLKSQPEKFKNVREFVCSGGVSSNQRLRTKLETELGTLNSTSFFNFYYPPMDLCSDNSIMIGWAGIEIWESLRLVSDLDICPIRQWPLNDLLSVDGWRTDQL 6ne7 A 1.99 BS01 AMP A 1 V738 A756 E805 Y806 A807 L881 V39 A57 E106 Y107 A108 L163 D874 R878 N879 D892 D156 R160 N161 D174 2.7.10.1 0004672,0004713,0005524,0006468 P07949 31118272 1103 GPLSLSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYASLRGFLRESRKVGERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRR 6nfe A 1.75 BS02 AMP A 1 Y147 R176 A179 K182 Y146 R175 A178 K181 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009156,0009165,0016301,0016310,0044249,0046872 Q5ZY30 506 STMMIFTGNANPELALKISSHLQIPIGKATVGTFSDGETMVEILENVRGKDVFVLQSTCAPANNNLMELLIMADALRRSSAGRITAVVPYFGYARQDRRVRSARVPITAKVVADMMASVGICRVLTVDLHADQIQGFFYMPVDNVYSTPVLLEDITKQKLNNIMIVSPDVGGVVRARAVAKRLNDAELSIIDKRREVMHIIGEPANKNCIIVDDIVDTAGTLCTAAHELKKNGAKSVRAYITHPVLSGPAVNNIKHSGLDEVVVTDTIPLSAEAQNCEKIRVVSLADMLAQAIKRVNV 6nfe A 1.75 BS03 AMP A 2 R99 V101 R98 V100 2.7.6.1 0000287,0002189,0004749,0005524,0005737,0006015,0006164,0009156,0009165,0016301,0016310,0044249,0046872 Q5ZY30 508 STMMIFTGNANPELALKISSHLQIPIGKATVGTFSDGETMVEILENVRGKDVFVLQSTCAPANNNLMELLIMADALRRSSAGRITAVVPYFGYARQDRRVRSARVPITAKVVADMMASVGICRVLTVDLHADQIQGFFYMPVDNVYSTPVLLEDITKQKLNNIMIVSPDVGGVVRARAVAKRLNDAELSIIDKRREVMHIIGEPANKNCIIVDDIVDTAGTLCTAAHELKKNGAKSVRAYITHPVLSGPAVNNIKHSGLDEVVVTDTIPLSAEAQNCEKIRVVSLADMLAQAIKRVNV 6o3p A 1.6 BS01 AMP A 1 D322 G355 F356 E370 E415 D175 G208 F209 E223 E268 3.6.1.-,3.6.1.22 0016787,0046872 Q9DCN1 31101919 501 SHMLDRRSDKRNNSDWLQAKESHPTTVYLLFSDLNPLVTLGGNKESSQQPEVRLCQLNYPDVKGYLAQPEKITLVFLGVELDGLVAWFALGIEPGAAENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGSATKIEEGGYKRVCVRETCPSLQGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVSCQPWPMPSSLMIGCLAVAVSTEIKVDKNEIEDARWFTREQVVDVLTKGQAFFVPPSRAIAHQLIKHWVG 6o3p A 1.6 BS05 AMP B 1 V313 N315 Y318 V166 N168 Y171 3.6.1.-,3.6.1.22 0016787,0046872 Q9DCN1 31101919 502 SHMLDRRSDKRNNSDWLQAKESHPTTVYLLFSDLNPLVTLGGNKESSQQPEVRLCQLNYPDVKGYLAQPEKITLVFLGVELDGLVAWFALGIEPGAAENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGSATKIEEGGYKRVCVRETCPSLQGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVSCQPWPMPSSLMIGCLAVAVSTEIKVDKNEIEDARWFTREQVVDVLTKGQAFFVPPSRAIAHQLIKHWVG 6o3p B 1.6 BS01 AMP A 1 V313 N315 Y318 V178 N180 Y183 3.6.1.-,3.6.1.22 0016787,0046872 Q9DCN1 31101919 501 HMLDRRSDKRNNSDWLQAKESHPTTVYLLFSDLNPLVTLGGNKESSQQPEVRLCQLNYPDVKGYLAQPEKITLVFLGVELEMRKAADGLVAWFALGIEPGAAEEFKQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGSATKIEEGGYKRVCVRETCPSLQGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVSCQPWPMPSSLMIGCLAVAVSTEIKVDKNEIEDARWFTREQVVDVLTAFFVPPSRAIAHQLIKHWVGMNP 6o3p B 1.6 BS03 AMP B 1 D322 G355 F356 E370 E415 D187 G220 F221 E235 E280 3.6.1.-,3.6.1.22 0016787,0046872 Q9DCN1 31101919 502 HMLDRRSDKRNNSDWLQAKESHPTTVYLLFSDLNPLVTLGGNKESSQQPEVRLCQLNYPDVKGYLAQPEKITLVFLGVELEMRKAADGLVAWFALGIEPGAAEEFKQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGSATKIEEGGYKRVCVRETCPSLQGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVSCQPWPMPSSLMIGCLAVAVSTEIKVDKNEIEDARWFTREQVVDVLTAFFVPPSRAIAHQLIKHWVGMNP 6o6q A 2.7 BS01 AMP A 1 L49 V57 I120 H164 M167 I178 L46 V54 I113 H157 M160 I171 D160 K162 N165 D179 S198 D153 K155 N158 D172 S191 2.7.11.1 0004672,0004674,0005524,0005634,0005829,0005956,0006356,0006359,0006468,0006974,0016310,0042273,0051726,0106310 A0A1D8PUA2 401 HRHNTVQSVSRVYADVLSTKPQSYWDYDDLNIKWNPQENYEILRKLGRGKYSEVFLGIDLEKREKVVIKVLKPVKRKKIKREISILKNLVDGPNIIAMLDVVRETPGLIFEHINNIDFRSLYPTFTDYDIRFYMYELLKALDYSHSMGIMHRDVKPHNVMIDHDKKLLRLIDWGLAEYYHPGTEYNVRVASRYFKGPELLVDYRLYDYSLDMWSFGCMLASMVFMKEPFFHGKSNTDQLVQIVRVLGSKNFKKYLEKYNISLGEEYEDIGYYNKRQWVRFMNENNKDLVSQEFLDLIDRLLRYDHQERLTAKEAMKHAYFDPIRVA 6o6q B 2.7 BS01 AMP B 1 L49 V57 V70 H119 I120 H164 M167 L45 V53 V66 H111 I112 H156 M159 D160 K162 N165 D179 S198 D152 K154 N157 D171 S190 2.7.11.1 0004672,0004674,0005524,0005634,0005829,0005956,0006356,0006359,0006468,0006974,0016310,0042273,0051726,0106310 A0A1D8PUA2 401 RHNTVQSVSRVYADVLSTKPQSYWDYDDLNIKWNPQENYEILRKLGRGKYSEVFLGIDLEKREKVVIKVLKPVKRKKIKREISILKNLVDGPNIIAMLDVVRKTPGLIFEHINNIDFRSLYPTFTDYDIRFYMYELLKALDYSHSMGIMHRDVKPHNVMIDHDKKLLRLIDWGLAEYYHPGTEYNVRVASRYFKGPELLVDYRLYDYSLDMWSFGCMLASMVFMKEPFFHGKSNTDQLVQIVRVLGSKNFKKYLEKYNISLGEEYEDIGYYNKRQWVRFMNENNKDLVSQEFLDLIDRLLRYDHQERLTAKEAMKHAYFDPIRVA 6ofb A 2.84 BS02 AMP A 1 P355 L356 S357 M418 R489 C531 P353 L354 S355 M416 R487 C529 6.3.5.1 0003952,0004359,0005515,0005524,0005737,0005829,0009435,0016874,0034627 Q6IA69 31911602 902 RKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHYYESDTLLHSFQVLAALLESPVTQDIICDVGMPVMHRNVRYNCRVIFLNRKILLIRPKMALANEGNYRELRWFTPWSRSRHTEEYFLPRMIQDLTKQETVPFGDAVLVTWDTCIGSEICEELWTPHSPHIDMGLDGVEIITNASGSHHVLRKANTRVDLVTMVTSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSVFAQGSQFSLDDVEVLTATLDLEDVRSYRAEISSRNLAASRASPYPRVKVDFALSCHEDLLAPISEPIEWKYHSPEEEISLGPACWLWDFLRRSQQAGFLLPLSGGVDSAATACLIYSMCCQVCEAVRSGNEEVLADVRTIVNQISYTPQDPRDLCGRILTTCYMASKNSSQETCTRARELAQQIGSHHISLNIDPAVKAVMGIFSLVTGKSPLFAAHGGSSRENLALQNVQARIRMVLAYLFAQLSLWSRGVHGGLLVLGSANVDESLLGYLTKYDCSSADINPIGGISKTDLRAFVQFCIQRFQLPALQSILLAPATAELEPLADGQVSQTDEEDMGMTYAELSVYGKLRKVAKMGPYSMFCKLLGMWRHICTPRQVADKVKRFFSKYSMNRHKMTTLTPAYHAENYSPEDNRFDLRPFLYNTSWPWQFRCIENQVLQLERAE 6ofb B 2.84 BS03 AMP B 1 P355 L356 S357 M418 R489 A573 P353 L354 S355 M416 R487 A571 6.3.5.1 0003952,0004359,0005515,0005524,0005737,0005829,0009435,0016874,0034627 Q6IA69 31911602 902 RKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHYYESDTLLHSFQVLAALLESPVTQDIICDVGMPVMHRNVRYNCRVIFLNRKILLIRPKMALANEGNYRELRWFTPWSRSRHTEEYFLPRMIQDLTKQETVPFGDAVLVTWDTCIGSEICEELWTPHSPHIDMGLDGVEIITNASGSHHVLRKANTRVDLVTMVTSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSVFAQGSQFSLDDVEVLTATLDLEDVRSYRAEISSRNLAASRASPYPRVKVDFALSCHEDLLAPISEPIEWKYHSPEEEISLGPACWLWDFLRRSQQAGFLLPLSGGVDSAATACLIYSMCCQVCEAVRSGNEEVLADVRTIVNQISYTPQDPRDLCGRILTTCYMASKNSSQETCTRARELAQQIGSHHISLNIDPAVKAVMGIFSLVTGKSPLFAAHGGSSRENLALQNVQARIRMVLAYLFAQLSLWSRGVHGGLLVLGSANVDESLLGYLTKYDCSSADINPIGGISKTDLRAFVQFCIQRFQLPALQSILLAPATAELEPLADGQVSQTDEEDMGMTYAELSVYGKLRKVAKMGPYSMFCKLLGMWRHICTPRQVADKVKRFFSKYSMNRHKMTTLTPAYHAENYSPEDNRFDLRPFLYNTSWPWQFRCIENQVLQLERAE 6oms A 1.942 BS01 AMP A 1 S95 S96 V299 T301 T324 Y325 G326 S327 S328 Y347 D398 F414 R417 S87 S88 V291 T293 T316 Y317 G318 S319 S320 Y339 D390 F406 R409 6.3.2.- 0005515,0006952,0009626,0009863,0010112,0016046,0016874,0018874,0034052,0042742,0052625,0052626,0052627,0052628,0071456 Q9LYU4 31575658 601 ETFEKQLKDLTSNVKSIQDNLLEEIITPNTKTEYLQRFLIDRFDKELFKKNVPIVSYEDIKPYLDRVVNGESSDVISARTITGFLLSSGTSGGAQKMMPWNNKYLDNLTFIYDLRMQVITKHVKGVEEGKGMMFLFTKQESMTPSGLPARVATSSYFKSDYFKNRPSNWYYSYTSPDEVILCPNNTESLYCHLLCGLVQRDEVVRTGSIFASVMVRAIEVLKNSWEELCSNIRSGHLSNWVTDLGCQNSVSLVLGGPRPELADTIEEICNQNSWKGIVKRLWPNTKYIETVVTGSMGQYVPMLNYYCNDLPLVSTTYGSSETTFGINLDPLCKPEDVSYTFMPNMSYFEFIPMDGGDKNDVVDLEDVKLGCTYEPVVTNFAGLYRMRVGDIVLVTGFYNNAPQFKFVRRENVVLSIDSDKTNEEDLFKAVSQTSYADTSTFPGHYVVYLLSTCCLVMEESLDNVYKRCRFKDGSIGPLEIRAKFFSI 6oms B 1.942 BS01 AMP B 1 S95 S96 V299 T301 T324 Y325 G326 S327 S328 Y347 D398 F414 R417 S88 S89 V292 T294 T317 Y318 G319 S320 S321 Y340 D391 F407 R410 6.3.2.- 0005515,0006952,0009626,0009863,0010112,0016046,0016874,0018874,0034052,0042742,0052625,0052626,0052627,0052628,0071456 Q9LYU4 31575658 601 NETFEKQLKDLTSNVKSIQDNLLEEIITPNTKTEYLQRFLIDRFDKELFKKNVPIVSYEDIKPYLDRVVNGESSDVISARTITGFLLSSGTSGGAQKMMPWNNKYLDNLTFIYDLRMQVITKHVKGVEEGKGMMFLFTKQESMTPSGLPARVATSSYFKSDYFKNRPSNWYYSYTSPDEVILCPNNTESLYCHLLCGLVQRDEVVRTGSIFASVMVRAIEVLKNSWEELCSNIRSGHLSNWVTDLGCQNSVSLVLGGPRPELADTIEEICNQNSWKGIVKRLWPNTKYIETVVTGSMGQYVPMLNYYCNDLPLVSTTYGSSETTFGINLDPLCKPEDVSYTFMPNMSYFEFIPMDGGDKNDVVDLEDVKLGCTYEPVVTNFAGLYRMRVGDIVLVTGFYNNAPQFKFVRRENVVLSIDSDKTNEEDLFKAVSQAKTSYADTSTFPGHYVVYLLSTCCLVMEESLDNVYKRCRFKDGSIGPLEIRVVAKFFSI 6oqq A 2.102 BS01 AMP A 1 H492 R500 D502 Y506 Q507 V510 Q517 Q519 G521 H394 R402 D404 Y408 Q409 V412 Q419 Q421 G423 6.-.-.- 0000166,0006508,0008234,0016740,0016874,0046872 Q5ZTK6 31123136 901 VKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWR 6oqq C 2.102 BS01 AMP C 1 H492 R500 D502 Y506 Q507 V510 Q517 Q519 G521 H393 R401 D403 Y407 Q408 V411 Q418 Q420 G422 6.-.-.- 0000166,0006508,0008234,0016740,0016874,0046872 Q5ZTK6 31123136 901 KQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQ 6oz1 A 1.97 BS01 AMP A 1 S399 A400 P401 G421 Y422 T425 D498 Y510 R513 K621 S401 A402 P403 G423 Y424 T427 D500 Y512 R515 K623 T261 L281 H304 T425 E426 K519 L520 F525 K621 T263 L283 H306 T427 E428 K521 L522 F527 K623 31886667 711 QGMTETISTPAATTTPDLADQQELERRVAQVVSNDPQLQALLPDDAVSGAVNEPGLTLIELIRRLLEGYGDRPALGQRAVELVTDEHGATTVALKTEFVTTSYRELWNRAEAIAAAWYAQGIRDGDFVAQLGFTSTDFASLDVAGLRLGTVSVPLQTGASVQQRNAILEETQPTVFAASVEYLEAAVDSVLATPSVQLLSVFDYHPEADAHRAALSAVRDRLETAGRTITIDSLGDAIARGRELPAAPQPSEDPDALRLLIYTSGSTGTPKGAMYPQWLVANLWQKKWLTTTVIPSVGVNFMPMSHLAGRLTLMGTLSGGGTAYYIASSDLSTFFEDIALIRPTEVLFVPRVVEMVFQRYQAELDRSLAPGESNAEIAEKIKVRIREEDFGGRVLNAGSGSAPLSPEMNDFMESLLQVAMLDGYGSTEAGAVWRDGVLQRPPVTEYKLVDVPELGYFTTDSPHPRGELRIKSETMFPGYYKRPETTADVFDEDGFYMTGDVVAELGPDHLKYLDRVKNVLKLAQGEFVAVSKLEAAYTGSPLVRQIFVYGNSERSYLLAVVVPTPEALERYADSPDALKPLIQDSLQQVAKGAELQSYEIPRDFIVETVPFTVESGLLSDARKLLRPKLKEHYGERLEALYAD 6ozv A 2.18 BS01 AMP A 1 G2869 E2870 A2871 L2892 Y2893 P2895 T2896 D2985 Y2997 G705 E706 A707 L728 Y729 P731 T732 D821 Y833 T2753 E2897 T589 E733 ? 0003824 A0A0B5GUD2 3101 PLSFAQQRLWFIAQMSREASGAYHVPGGLRLRGELDEVALRAALDRIMARHEVLRTRFEWHEGEPVQCIDAEARFPLVRQELEGEAAELAHWQQVEARSPFDLGTGPLIRGRLLKQEHVLLLTMHHIVSDGWSMSVLAHELGTLYRAYAQEPEVPALPLQYADYALWQRRWLDGERQQRQLAYWQQQLAGAPALVSLPTDRPRPALQDYRGDSIELTFDAGLSQGLRALSQRHGTTLYMTVLAAWAALVARLAGQPEVVIGTPVANRQRAELEGLIGFFVNTLALRVDLGGEPSVAGLLAQVRERVLAAQSHQDLPFEQVVEALKPERSLSHSPVFQLMLSWESSPVRERSAQFDLSLHLHEAADGTVAGSLTYASALYERETVQRHAGYLKALLAGMVADDTQPVQRIGILGEAERHRLLVEWNDTAREHPRTVCVHELFEQQVERSPDAVALVYEGQQLSYRELDRQANRLARQLKALGVGPDERVAVCTERCLEMVVALLAVLKAGGAYVPLDPGYPAERLEYMLADSAPKVLLRQSGQTLEPGAGVAVLALDGEASQPWQAQPAQRLSRDDSGVQPHHLAYVIYTSGSTGRPKGVMVEHAGVVNRLLWMQRAYGLQPQEAVLQKTPFGFDVSVWEFFWPLAVGARLVMARPQGQQDPAYLVETIVGQDIGTLHFVPSMLQAFVDSEGVQRCRGVRRIVCSGEALPGALARRLRQQLPQVELHNLYGPTEATVDVTAWACDAAELPDNIPIGRPVDNTTMYVLDAHGQPVPTGVAGEIHIGGVQVARGYLGRPELTRERFVPDPYAGRPGARLYKTGDLGRWLLDGTLEYLGRND 6p08 A 2.27 BS04 AMP A 1 E145 K149 E144 K148 2.7.7.- 0016740,0016779,0046677 P05058 305 NGPIIMTREERMKIVHEIKERILDKYGDDVKAIGVYGSLGRQTDGPYSDIDMMCVMSTEEAEFSHEWTTGEWKVEVNFDSEEILLDYASQVESDWPLTHGQFFSILPIYDSGGYLEKVYQTAKSVEAQKFHDAICALIVEELFEYAGKWRNIRVQGPTTFLPSLTVQVAMAGAMLIGLHHRICYTTSASVLTEAVKQSDLPSGYDHLCQFVMSGQLSDSEKLLESLENFWNGIQEWTERHGYIVDVSKRIPF 6p08 A 2.27 BS05 AMP A 2 Y37 G38 D52 T99 Y36 G37 D51 T98 2.7.7.- 0016740,0016779,0046677 P05058 306 NGPIIMTREERMKIVHEIKERILDKYGDDVKAIGVYGSLGRQTDGPYSDIDMMCVMSTEEAEFSHEWTTGEWKVEVNFDSEEILLDYASQVESDWPLTHGQFFSILPIYDSGGYLEKVYQTAKSVEAQKFHDAICALIVEELFEYAGKWRNIRVQGPTTFLPSLTVQVAMAGAMLIGLHHRICYTTSASVLTEAVKQSDLPSGYDHLCQFVMSGQLSDSEKLLESLENFWNGIQEWTERHGYIVDVSKRIPF 6p08 D 2.27 BS02 AMP A 1 Y37 D52 T99 Y36 D51 T98 2.7.7.- 0016740,0016779,0046677 P05058 305 NGPIIMTREERMKIVHEIKERILDKYGDDVKAIGVYGSLGRQTDGPYSDIDMMCVMSTEEAEFSHEWTTGEWKVEVNFDSEEILLDYASQVESDWPLTHGQFFSILPIYDSGGYLEKVYQTAKSVEAQKFHDAICALIVEELFEYAGKWRNIRVQGPTTFLPSLTVQVAMAGAMLIGLHHRICYTTSASVLTEAVKQSDLPSGYDHLCQFVMSGQLSDSEKLLESLENFWNGIQEWTERHGYIVDVSKRIPF 6p08 D 2.27 BS03 AMP A 2 E145 K149 E144 K148 2.7.7.- 0016740,0016779,0046677 P05058 306 NGPIIMTREERMKIVHEIKERILDKYGDDVKAIGVYGSLGRQTDGPYSDIDMMCVMSTEEAEFSHEWTTGEWKVEVNFDSEEILLDYASQVESDWPLTHGQFFSILPIYDSGGYLEKVYQTAKSVEAQKFHDAICALIVEELFEYAGKWRNIRVQGPTTFLPSLTVQVAMAGAMLIGLHHRICYTTSASVLTEAVKQSDLPSGYDHLCQFVMSGQLSDSEKLLESLENFWNGIQEWTERHGYIVDVSKRIPF 6p09 A 2.052 BS04 AMP C 1 K568 Y569 R573 E621 F660 M723 K725 W742 K744 K309 Y310 R314 E362 F401 M464 K466 W483 K485 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 31780661 101 SNDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 6p0a A 2.05 BS04 AMP C 1 Y567 K568 Y569 R573 E621 F660 M723 K725 K744 Y305 K306 Y307 R311 E359 F398 M461 K463 K482 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 31780661 101 SNDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 6p0b A 2.203 BS04 AMP C 1 E566 Y567 K568 Y569 R573 E621 F660 M723 K725 K744 E307 Y308 K309 Y310 R314 E362 F401 M464 K466 K485 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 31780661 101 SNDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 6p0c A 1.55 BS04 AMP C 1 K568 Y569 R573 E621 F660 M723 K725 W742 K744 K309 Y310 R314 E362 F401 M464 K466 W483 K485 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 31780661 101 SNDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 6p0d A 1.75 BS04 AMP C 1 K568 Y569 R573 E621 F660 M723 K725 W742 K744 K308 Y309 R313 E361 F400 M463 K465 W482 K484 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 31780661 101 NDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 6p0e A 1.85 BS04 AMP C 1 K568 Y569 R573 E621 F660 M723 K725 W742 K744 K309 Y310 R314 E362 F401 M464 K466 W483 K485 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 31780661 101 SNDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 6p4u A 2.1 BS01 AMP A 1 G2869 E2870 A2871 L2892 Y2893 G2894 T2896 D2985 Y2997 G710 E711 A712 L733 Y734 G735 T737 D826 Y838 T2753 E2897 T594 E738 ? 0003824 A0A0B5GUD2 3101 APLSFAQQRLWFIAQMSREASGAYHVPGGLRLRGELDEVALRAALDRIMARHEVLRTRFEWHEGEPVQCIDAEARFPLVRQELEGEAAELAHWQQVEARSPFDLGTGPLIRGRLLKLQEHVLLLTMHHIVSDGWSMSVLAHELGTLYRAYAQEVDPLPALPLQYADYALWQRRWLDGERQQRQLAYWQQQLAGAPALVSLPTDRPRPALQDYRGDSIELTFDAGLSQGLRALSQRHGTTLYMTVLAAWAALVARLAGQPEVVIGTPVANRQRAELEGLIGFFVNTLALRVDLGGEPSVAGLLAQVRERVLAAQSHQDLPFEQVVEALKPERSLSHSPVFQLMLSWESSLAPVRERSAQFDLSLHLHEAADGTVAGSLTYASALYERETVQRHAGYLKALLAGMVADDTQPVQRIGILGEAERHRLLVEWNDTAREHPRTVCVHELFEQQVERSPDAVALVYEGQQLSYRELDRQANRLARQLKALGVGPDERVAVCTERCLEMVVALLAVLKAGGAYVPLDPGYPAERLEYMLADSAPKVLLRQSGQTLEPGAGVAVLALDGEASQPWQAQPAQRLSRDDSGVQPHHLAYVIYTSGSTGRPKGVMVEHAGVVNRLLWMQRAYGLQPQEAVLQKTPFGFDVSVWEFFWPLAVGARLVMARPQGQQDPAYLVETIVGQDIGTLHFVPSMLQAFVDSEGVQRCRGVRRIVCSGEALPGALARRLRQQLPQVELHNLYGPTEATVDVTAWACDAAELPDNIPIGRPVDNTTMYVLDAHGQPVPTGVAGEIHIGGVQVARGYLGRPELTRERFVPDPYAGRPGARLYKTGDLGRWLLDGTLEYLGRND 6p63 A 2.4 BS01 AMP A 1 G155 H156 Q277 N301 M302 R306 H443 E445 N446 D463 E467 G154 H155 Q276 N300 M301 R305 H442 E444 N445 D462 E466 ? 0005524,0009058,0016881,0019290,0046872 Q9L069 32885650 601 SLADAVAHLTPERWEEANRLLVRKALAEFTHERLLTPEREPDDGGGQTYVVRSDDGQTAYRFTATVRALDHWQVDAASVTRHRDGAELPLAALDFFIELKQTLGLSDEILPVYLEEISSTLSGTCYKLTKPQLSSAELARSGDFQAVETGMTEGHPCFVANNGRLGFGIHEYLSYAPETASPVRLVWLAAHRSRAAFTAGVGIEYESFVRDELGAATVDRFHGVLRGRGLDPADYLLIPVHPWQWWNKLTVTFAAEVARGHLVCLGEGDDEYLAQQSIRTFFNASHPGKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLARLIEGDPVLKETGLSIIRERAAVGYRHLEYEQATDRYSPYRKMLAALWRESPVPSIREGETLATMASLVHQDHEGASFAGALIERSGLTPTEWLRHYLRAYYVPLLHSFYAYDLVYMPHGENVILVLADGVVRRAVYKDIAEEIAVMDPDAVLPPEVSRIAVDVPDDKKLLSIFTDVFDCFFRFLAANLAEEGIVTEDAFWRTVAEVTREYQESVPELADKFERYDMFAPEFALSCLNRLQLRDNRQMVDLADPSGALQLVGTLKNPLAGR 6p63 B 2.4 BS01 AMP B 1 G155 H156 Q277 N301 M302 R306 H443 E445 N446 D463 E467 G154 H155 Q276 N300 M301 R305 H442 E444 N445 D462 E466 ? 0005524,0009058,0016881,0019290,0046872 Q9L069 32885650 601 SLADAVAHLTPERWEEANRLLVRKALAEFTHERLLTPEREPDDGGGQTYVVRSDDGQTAYRFTATVRALDHWQVDAASVTRHRDGAELPLAALDFFIELKQTLGLSDEILPVYLEEISSTLSGTCYKLTKPQLSSAELARSGDFQAVETGMTEGHPCFVANNGRLGFGIHEYLSYAPETASPVRLVWLAAHRSRAAFTAGVGIEYESFVRDELGAATVDRFHGVLRGRGLDPADYLLIPVHPWQWWNKLTVTFAAEVARGHLVCLGEGDDEYLAQQSIRTFFNASHPGKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLARLIEGDPVLKETGLSIIRERAAVGYRHLEYEQATDRYSPYRKMLAALWRESPVPSIREGETLATMASLVHQDHEGASFAGALIERSGLTPTEWLRHYLRAYYVPLLHSFYAYDLVYMPHGENVILVLADGVVRRAVYKDIAEEIAVMDPDAVLPPEVSRIAVDVPDDKKLLSIFTDVFDCFFRFLAANLAEEGIVTEDAFWRTVAEVTREYQESVPELADKFERYDMFAPEFALSCLNRLQLRDNRQMVDLADPSGALQLVGTLKNPLAGR 6p63 C 2.4 BS01 AMP C 1 G155 H156 Q277 N301 M302 R306 H443 E445 N446 D463 E467 G155 H156 Q277 N301 M302 R306 H443 E445 N446 D463 E467 ? 0005524,0009058,0016881,0019290,0046872 Q9L069 32885650 601 MSLADAVAHLTPERWEEANRLLVRKALAEFTHERLLTPEREPDDGGGQTYVVRSDDGQTAYRFTATVRALDHWQVDAASVTRHRDGAELPLAALDFFIELKQTLGLSDEILPVYLEEISSTLSGTCYKLTKPQLSSAELARSGDFQAVETGMTEGHPCFVANNGRLGFGIHEYLSYAPETASPVRLVWLAAHRSRAAFTAGVGIEYESFVRDELGAATVDRFHGVLRGRGLDPADYLLIPVHPWQWWNKLTVTFAAEVARGHLVCLGEGDDEYLAQQSIRTFFNASHPGKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLARLIEGDPVLKETGLSIIRERAAVGYRHLEYEQATDRYSPYRKMLAALWRESPVPSIREGETLATMASLVHQDHEGASFAGALIERSGLTPTEWLRHYLRAYYVPLLHSFYAYDLVYMPHGENVILVLADGVVRRAVYKDIAEEIAVMDPDAVLPPEVSRIAVDVPDDKKLLSIFTDVFDCFFRFLAANLAEEGIVTEDAFWRTVAEVTREYQESVPELADKFERYDMFAPEFALSCLNRLQLRDNRQMVDLADPSGALQLVGTLKNPLAGR 6p63 D 2.4 BS01 AMP D 1 G155 H156 Q277 N301 M302 R306 H443 E445 N446 D463 E467 G154 H155 Q276 N300 M301 R305 H442 E444 N445 D462 E466 ? 0005524,0009058,0016881,0019290,0046872 Q9L069 32885650 601 SLADAVAHLTPERWEEANRLLVRKALAEFTHERLLTPEREPDDGGGQTYVVRSDDGQTAYRFTATVRALDHWQVDAASVTRHRDGAELPLAALDFFIELKQTLGLSDEILPVYLEEISSTLSGTCYKLTKPQLSSAELARSGDFQAVETGMTEGHPCFVANNGRLGFGIHEYLSYAPETASPVRLVWLAAHRSRAAFTAGVGIEYESFVRDELGAATVDRFHGVLRGRGLDPADYLLIPVHPWQWWNKLTVTFAAEVARGHLVCLGEGDDEYLAQQSIRTFFNASHPGKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLARLIEGDPVLKETGLSIIRERAAVGYRHLEYEQATDRYSPYRKMLAALWRESPVPSIREGETLATMASLVHQDHEGASFAGALIERSGLTPTEWLRHYLRAYYVPLLHSFYAYDLVYMPHGENVILVLADGVVRRAVYKDIAEEIAVMDPDAVLPPEVSRIAVDVPDDKKLLSIFTDVFDCFFRFLAANLAEEGIVTEDAFWRTVAEVTREYQESVPELADKFERYDMFAPEFALSCLNRLQLRDNRQMVDLADPSGALQLVGTLKNPLAGR 6p6u C 2.42 BS01 AMP C 1 V234 D235 Y238 K242 V234 D235 Y238 K242 1.1.1.27 0003824,0004459,0005737,0006089,0006090,0016491,0016616,0019752 P13491 401 AALKDQLIHNLLKEEHVPQNKITVVGVGAVGMACAISILMKDLADELALVDVMEDKLKGEMMDLQHGSLFLRTPKIVSGKDYSVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPHCKLLVVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHALSCHGWILGEHGDSSVPVWSGMNVAGVSLKTLHPELGTDADKEQWKQVHKQVVDSAYEVIKLKGYTTWAIGLSVADLAESIMKNLRRVHPISTMLKGLYGIKEDVFLSVPCVLGQNGISDVVKVTLTSEEEAHLKKSADTLWGIQKELQF 6p6u E 2.42 BS01 AMP E 1 D194 V234 D235 Y238 K242 D194 V234 D235 Y238 K242 1.1.1.27 0003824,0004459,0005737,0006089,0006090,0016491,0016616,0019752 P13491 401 AALKDQLIHNLLKEEHVPQNKITVVGVGAVGMACAISILMKDLADELALVDVMEDKLKGEMMDLQHGSLFLRTPKIVSGKDYSVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPHCKLLVVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHALSCHGWILGEHGDSSVPVWSGMNVAGVSLKTLHPELGTDADKEQWKQVHKQVVDSAYEVIKLKGYTTWAIGLSVADLAESIMKNLRRVHPISTMLKGLYGIKEDVFLSVPCVLGQNGISDVVKVTLTSEEEAHLKKSADTLWGIQKELQF 6p8q B 1.9 BS01 AMP B 1 S720 G721 V726 A743 K745 M790 M793 L844 D855 S23 G24 V29 A46 K48 M93 M96 L147 D158 D837 R841 N842 D855 D140 R144 N145 D158 2.7.10.1 0004672,0004713,0005524,0006468 P00533 31749909 2001 APNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDM 6p8q C 1.9 BS01 AMP C 1 L718 G719 S720 G721 V726 A743 K745 M790 L792 M793 C797 L844 D855 L20 G21 S22 G23 V28 A45 K47 M92 L94 M95 C99 L146 D157 D837 R841 N842 D855 D139 R143 N144 D157 2.7.10.1 0004672,0004713,0005524,0006468 P00533 31749909 2001 PNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDAD 6p8q D 1.9 BS01 AMP D 1 L718 G721 V726 A743 K745 M790 M793 R841 L844 D855 L19 G22 V27 A44 K46 M91 M94 R142 L145 D156 D837 R841 N842 D855 D138 R142 N143 D156 2.7.10.1 0004672,0004713,0005524,0006468 P00533 31749909 2001 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDM 6pjw A 2.4 BS01 AMP A 1 F39 G40 M43 R56 M59 R60 Q71 T91 H92 V95 G104 R138 F38 G39 M42 R55 M58 R59 Q70 T90 H91 V94 G103 R137 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 301 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw A 2.4 BS02 AMP A 2 G13 G15 T18 R131 N175 L180 G12 G14 T17 R130 N174 L179 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 302 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw B 2.4 BS01 AMP B 1 F39 G40 M43 R56 M59 R60 Q71 T91 H92 V95 G104 R138 F38 G39 M42 R55 M58 R59 Q70 T90 H91 V94 G103 R137 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 301 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw B 2.4 BS02 AMP B 2 G13 G15 T18 R131 N175 R176 G12 G14 T17 R130 N174 R175 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 302 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw C 2.4 BS01 AMP C 1 F39 G40 M43 R56 M59 R60 Q71 T91 H92 G104 R138 F38 G39 M42 R55 M58 R59 Q70 T90 H91 G103 R137 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 301 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw C 2.4 BS02 AMP C 2 G13 G15 T18 R131 R140 N175 R176 L180 G12 G14 T17 R130 R139 N174 R175 L179 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 302 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw D 2.4 BS01 AMP D 1 F39 G40 M43 R56 M59 R60 Q71 T91 H92 V95 G104 R138 F38 G39 M42 R55 M58 R59 Q70 T90 H91 V94 G103 R137 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 301 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw D 2.4 BS02 AMP D 2 G13 G15 T18 R131 N175 D177 G12 G14 T17 R130 N174 D176 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 302 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw E 2.4 BS01 AMP E 1 F39 G40 M43 R56 M59 R60 Q71 T91 H92 V95 G104 R138 F38 G39 M42 R55 M58 R59 Q70 T90 H91 V94 G103 R137 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 301 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw E 2.4 BS02 AMP E 2 G13 G15 T17 T18 R131 N175 D177 G12 G14 T16 T17 R130 N174 D176 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 302 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw F 2.4 BS01 AMP F 1 F39 G40 M43 M59 R60 Q71 T91 H92 V95 G104 R138 F38 G39 M42 M58 R59 Q70 T90 H91 V94 G103 R137 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 301 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw F 2.4 BS02 AMP F 2 G13 G15 T18 R131 N175 R176 D177 L180 G12 G14 T17 R130 N174 R175 D176 L179 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 302 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw G 2.4 BS01 AMP G 1 F39 G40 M43 R56 M59 R60 T91 H92 V95 G104 R138 F38 G39 M42 R55 M58 R59 T90 H91 V94 G103 R137 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 301 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw G 2.4 BS02 AMP G 2 G13 G15 T18 R131 N175 G12 G14 T17 R130 N174 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 302 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw H 2.4 BS01 AMP H 1 F39 G40 M43 R56 M59 R60 Q71 T91 H92 V95 G104 F38 G39 M42 R55 M58 R59 Q70 T90 H91 V94 G103 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 301 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw H 2.4 BS02 AMP H 2 G13 G15 T18 R131 N175 L180 G12 G14 T17 R130 N174 L179 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 302 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw I 2.4 BS01 AMP I 1 F39 G40 M43 M59 R60 T91 H92 V95 G104 F38 G39 M42 M58 R59 T90 H91 V94 G103 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 301 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw I 2.4 BS02 AMP I 2 G13 G15 T17 T18 R131 N175 R176 D177 G12 G14 T16 T17 R130 N174 R175 D176 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 302 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw J 2.4 BS01 AMP J 1 F39 G40 M43 M59 Q71 T91 H92 G104 R138 F38 G39 M42 M58 Q70 T90 H91 G103 R137 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 301 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw J 2.4 BS02 AMP J 2 G13 G15 T18 R131 N175 D177 L180 G12 G14 T17 R130 N174 D176 L179 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 302 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw K 2.4 BS01 AMP K 1 F39 G40 M43 R56 R60 Q71 T91 H92 V95 G104 R138 F38 G39 M42 R55 R59 Q70 T90 H91 V94 G103 R137 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 301 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw K 2.4 BS02 AMP K 2 G15 T18 R131 N175 D177 L180 G14 T17 R130 N174 D176 L179 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 302 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw L 2.4 BS01 AMP L 1 F39 G40 M43 R56 M59 R60 Q71 T91 H92 V95 G104 R138 F38 G39 M42 R55 M58 R59 Q70 T90 H91 V94 G103 R137 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 301 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw L 2.4 BS02 AMP L 2 G15 T17 T18 R131 N175 L180 G14 T16 T17 R130 N174 L179 2.7.4.3 0004017,0005524,0005737,0016301,0016310,0046940 P43408 302 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6plm A 2.592 BS04 AMP A 1 H492 H494 Y506 Q507 V510 Q517 Q519 G521 N733 R734 H395 H397 Y404 Q405 V408 Q415 Q417 G419 N631 R632 6.-.-.- Q5ZTK6 31682223 1004 HVKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFEDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWREARK 6plm B 2.592 BS04 AMP B 1 H492 Y506 Q507 V510 Q517 Q519 G521 N733 R734 H396 Y405 Q406 V409 Q416 Q418 G420 N632 R633 6.-.-.- Q5ZTK6 31682223 1004 GHVKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFEDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWREARKNLS 6pmh A 2.3 BS02 AMP A 1 G18 G21 D42 N43 S45 S46 S47 D64 I65 A86 F89 R196 G16 G19 D40 N41 S43 S44 S45 D62 I63 A84 F87 R194 S129 C131 G132 Y155 K159 S127 C129 G130 Y153 K157 ? 0000166 O26475 407 MDEFRAYDGKCVLVTGGAGCVGSNLTGNLAKAGANVIILDNLSSSYEWNIPEYENIEFVKGDILDDEVLKRVFKERPDYVFHLAAHFANQNSVDNPEKDLLVNGLGILKVLEYAQLVGVERFVYSSSGCGVYGLDSKIPFEEHDISISLHTPYQVTKLLGELYTNYFHNLYEMPIVNARFFNVFGPGEVPGKYRNVIPNFFYWAMNQQPLPITGDGSETRDWTFVEDIVRGLMAMGVRREAIGEAINLGSGTEHQVIEMAGIINELTENPAGVVYRPRRDWDAKTRLLSSIDKARRLLDYEPQVSFREGLERTHRWFTENWELIRKSAEF 6pmt A 2.3 BS01 AMP A 1 G246 G247 G275 E313 K316 C317 S320 G388 M389 R391 G193 G194 G222 E260 K263 C264 S267 G335 M336 R338 D59 K121 E222 D244 D6 K68 E169 D191 ? 0005524,0140662 P38646 501 AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLA 6q1v A 1.85 BS04 AMP C 1 K568 Y569 R573 E621 F660 M723 K725 W742 K744 K309 Y310 R314 E362 F401 M464 K466 W483 K485 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 31780661 101 SNDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQRDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 6qjz A 2.7 BS01 AMP A 1 H221 S296 A297 S298 A320 M321 T322 D401 L413 K418 K427 H213 S288 A289 S290 A312 M313 T314 D393 L405 K410 K419 T177 S197 H221 T322 E323 N422 K427 T169 S189 H213 T314 E315 N414 K419 ? 0000166,0006631,0016874,0031956 A0A3G8GC37 35359497 601 ETATTLTGLLQSVAKTFPSRRGISLAGKFDLTHSHLNELVESAADHLISAGIKPNDVVALTFPNTVEYVILFLAVIRVRATAAPLNAAYTAEEFEFYLSDSESKLLLTPLEGNKPAQDAASKLSIPLGSASLTKSEEETKLTISLKHPESGSVAKLINEPSDVALFLHTSGTTSRPKGVPLTQHNLVSSVKNIQSVYQLTESDSTVIVLPLFHVHGLIAGLLSSLGSGAAVVLPAAGRFSASTFWKDMIQYNATWYTAVPTIHQIILDRHLNNPEPAYPKLRFIRSCSASLAPVILGRLEESFGAPVLEAYAMTEASHLMSSNPLPQNGPHKAGSVGKPVGQEMAILDESGRVLEAGVNGEVCIRGENVTKGYKNNEAANTAAFLFGWFHTGDIGYFDSDGYLHLVGRIKELINRGGEKISPIEVDAVLLSHPDVAQAVAFGIPDQKYGEEIHCAIIPREGSNIDAEEVLTFCKKNLASFKVPKKVFITDSLPRRLVAEHFVSK 6r8u A 3.0 BS01 AMP A 1 R40 H46 R52 T79 E370 R386 A387 R419 R34 H40 R46 T73 E364 R380 A381 R413 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 501 NDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 6r8u B 3.0 BS01 AMP B 1 R40 H46 R52 T79 E370 R386 A387 R419 R34 H40 R46 T73 E364 R380 A381 R413 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 501 NDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 6r8u C 3.0 BS01 AMP C 1 R40 H46 R52 T79 E370 R386 A387 R419 R34 H40 R46 T73 E364 R380 A381 R413 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 501 NDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 6r8u D 3.0 BS01 AMP D 1 R40 H46 R52 T79 E370 R386 A387 R419 R34 H40 R46 T73 E364 R380 A381 R413 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 501 NDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 6rar I 1.785 BS04 AMP D 1 K167 L168 R172 E220 F249 L290 M322 K324 K340 K163 L164 R168 E216 F245 L286 M318 K320 K336 6.5.1.1 0000166,0003909,0003910,0005524,0006260,0006281,0006310,0016874,0046872 A0A0A2ACP7 31312841 300 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLRCGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGF 6ras I 2.75 BS04 AMP D 1 K167 L168 R172 E220 F249 M322 K324 K340 K163 L164 R168 E216 F245 M318 K320 K336 6.5.1.1 0000166,0003909,0003910,0005524,0006260,0006281,0006310,0016874,0046872 A0A0A2ACP7 31312841 300 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLACGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGFK 6rau I 1.99 BS03 AMP I 1 K167 L168 R172 E220 F249 M322 K324 K340 K163 L164 R168 E216 F245 M318 K320 K336 6.5.1.1 0000166,0003909,0003910,0005524,0006260,0006281,0006310,0016874,0046872 A0A0A2ACP7 31312841 501 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLRCGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGF 6rce I 1.946 BS04 AMP D 1 K167 L168 R172 E220 F249 M322 K324 K340 K163 L164 R168 E216 F245 M318 K320 K336 6.5.1.1 0000166,0003909,0003910,0005524,0006260,0006281,0006310,0016874,0046872 A0A0A2ACP7 31312841 300 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLRCGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGF 6rms A 1.74 BS01 AMP A 1 S197 E201 L202 S218 N219 G266 G267 G324 N325 S165 E169 L170 S186 N187 G234 G235 G280 N281 2.10.1.1,2.7.7.75 Q39054 31860061 504 MIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVASDGPGEYPVITVTPGTVAYVTTGGPIPDGADAVVQVEDTKVIGDKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKVYPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKELEKVLDEAVSSGVDIILTSGGVFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIRAKGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDPIRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSSVSAIIVSDISAFSI 6s2u A 2.95 BS02 AMP A 1 G248 R249 K251 S255 A275 V276 R277 Q347 G234 R235 K237 S241 A261 V262 R263 Q333 2.7.6.5 0015969 Q5SHL3 32393900 402 GLWNRLEPALAYLAPEERAKVREAYRFAEEAHRGQLRRSGEPYITHPVAVAEILAGLQMDADTVAAGLLHDTLEDCGVAPEELERRFGPTVRRIVEGETKVSKLYKRRAEDLRQMFIAMAEDVRIIIVKLADRLHNLRTLEHMPPEKQKRIAQETLEIYAPLAHRLGMGQLKWELEDLSFRYLHPEAFASLSARIQATQEARERLIQKAIHLLQETLARDELLQSQLQGFEVTGRPKHLYSIWKKMEREGKTLEQIYDLLAVRVILDPKPAPTRESQALREKQVCYHVLGLVHALWQPIPGRVKDYIAVPKPNGYQSLHTTVIALEGLPLEVQIRTREMHR 6shq A 3.2 BS01 AMP A 1 R40 H46 R52 T79 E370 R386 A387 R419 R33 H39 R45 T72 E363 R379 A380 R412 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 34235472 501 DHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 6shq B 3.2 BS01 AMP B 1 R40 H46 R52 T79 E370 R386 A387 R419 R33 H39 R45 T72 E363 R379 A380 R412 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 34235472 501 DHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 6shq C 3.2 BS01 AMP C 1 R40 H46 R52 T79 E370 R386 A387 R419 R33 H39 R45 T72 E363 R379 A380 R412 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 34235472 501 DHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 6shq D 3.2 BS01 AMP D 1 R40 H46 R52 T79 E370 R386 A387 R419 R33 H39 R45 T72 E363 R379 A380 R412 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 34235472 501 DHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 6si8 A 3.4 BS01 AMP A 1 R40 H46 R52 T79 E370 R386 A387 R34 H40 R46 T73 E364 R380 A381 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 34235472 501 NDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 6si8 B 3.4 BS01 AMP B 1 R40 H46 R52 T79 E370 R386 A387 R419 R34 H40 R46 T73 E364 R380 A381 R413 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 34235472 501 NDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 6si8 C 3.4 BS01 AMP C 1 R40 H46 R52 T79 E370 R386 A387 R419 R34 H40 R46 T73 E364 R380 A381 R413 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 34235472 501 NDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 6si8 D 3.4 BS01 AMP D 1 R40 H46 R52 T79 E370 R386 A387 R419 R34 H40 R46 T73 E364 R380 A381 R413 2.7.7.27 0000287,0005524,0005978,0008878,0009058,0010170,0016208,0016779,0042802,0051289 P0A6V1 34235472 501 NDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER 6siw A 1.96 BS01 AMP A 1 S88 A212 E213 P214 E235 Y236 G237 S238 T239 D299 V319 S84 A208 E209 P210 E231 Y232 G233 S234 T235 D295 V315 ? 0000166,0016874,0046872 A0A022MRT4 31903677 501 RPELGDWSSPAELAELQRSQLPRVLAQALRSPFYAARYRGTTPPRTADDFAGVEVTAKQDLRDQYPFGMLAVGREHLATYHESSGTAGEPTASYYTEEDWTDLAERFARKWTGIHPSDTFLVRTPYGLVITGHLAQAAGRLRGATVVPGDARSLATPLSRMVRVLKTLDVTLTWCNPTEITMLAAAAKAAGLRPDQDFPHLRAMFTAAEPLTEVRRRRLSEIWGGIPVVEEYGSTETGTIAGQCPEGRMHLWADRAIFEVYDPRTGTLSEAGRGQMVVTPLYRDAMPLLRYNLADDVEVSTDPCGCGWLLPTVTVLGRAGTGHRIGPATVTQQRLEELVFSLPAAYEVMFWRAKAHPDVLELEFEAPEPVRQRAVKELGAALDRELGVPHRITGLAPGTLVPAEALTAQRDILKARYLFAEDEDWDKAVMYF 6siw B 1.96 BS03 AMP B 1 S88 A212 E213 P214 E234 E235 Y236 G237 S238 T239 D299 V319 S89 A213 E214 P215 E235 E236 Y237 G238 S239 T240 D300 V320 ? 0000166,0016874,0046872 A0A022MRT4 31903677 501 AMSRSRPELGDWSSPAELAELQRSQLPRVLAQALRSPFYAARYRGTTPPRTADDFAGVEVTAKQDLRDQYPFGMLAVGREHLATYHESSGTAGEPTASYYTEEDWTDLAERFARKWTGIHPSDTFLVRTPYGLVITGHLAQAAGRLRGATVVPGDARSLATPLSRMVRVLKTLDVTLTWCNPTEITMLAAAAKAAGLRPDQDFPHLRAMFTAAEPLTEVRRRRLSEIWGGIPVVEEYGSTETGTIAGQCPEGRMHLWADRAIFEVYDPRTGTLSEAGRGQMVVTPLYRDAMPLLRYNLADDVEVSTDPCGCGWLLPTVTVLGRHRIGPATVTQQRLEELVFSLPAAYEVMFWRAKAHPDVLELEFEAPEPVRQRAVKELGAALDRELGVPHRITGLAPGTLVPAEALTAQRDILKARYLFAEDEDWDKAVMYF 6siy A 1.95 BS02 AMP A 1 S88 A212 E213 P214 E235 Y236 G237 S238 T239 D299 V319 S85 A209 E210 P211 E232 Y233 G234 S235 T236 D296 V316 ? 0000166,0016874,0046872 A0A022MRT4 31903677 502 SRPELGDWSSPAELAELQRSQLPRVLAQALRSPFYAARYRGTTPPRTADDFAGVEVTAKQDLRDQYPFGMLAVGREHLATYHESSGTAGEPTASYYTEEDWTDLAERFARKWTGIHPSDTFLVRTPYGLVITGHLAQAAGRLRGATVVPGDARSLATPLSRMVRVLKTLDVTLTWCNPTEITMLAAAAKAAGLRPDQDFPHLRAMFTAAEPLTEVRRRRLSEIWGGIPVVEEYGSTETGTIAGQCPEGRMHLWADRAIFEVYDPRTGTLSEAGRGQMVVTPLYRDAMPLLRYNLADDVEVSTDPCGCGWLLPTVTVLGRAGTGHRIGPATVTQQRLEELVFSLPAAYEVMFWRAKAHPDVLELEFEAPEPVRQRAVKELGAALDRELGVPHRITGLAPGTLVPAEALTAQRDILKARYLFAEDEDWDKAVMYF 6siy B 1.95 BS03 AMP B 1 S88 A212 E213 P214 E235 Y236 G237 S238 T239 D299 V319 S88 A212 E213 P214 E235 Y236 G237 S238 T239 D299 V319 ? 0000166,0016874,0046872 A0A022MRT4 31903677 501 MSRSRPELGDWSSPAELAELQRSQLPRVLAQALRSPFYAARYRGTTPPRTADDFAGVEVTAKQDLRDQYPFGMLAVGREHLATYHESSGTAGEPTASYYTEEDWTDLAERFARKWTGIHPSDTFLVRTPYGLVITGHLAQAAGRLRGATVVPGDARSLATPLSRMVRVLKTLDVTLTWCNPTEITMLAAAAKAAGLRPDQDFPHLRAMFTAAEPLTEVRRRRLSEIWGGIPVVEEYGSTETGTIAGQCPEGRMHLWADRAIFEVYDPRTGTLSEAGRGQMVVTPLYRDAMPLLRYNLADDVEVSTDPCGCGWLLPTVTVLGRAGTGHRIGPATVTQQRLEELVFSLPAAYEVMFWRAKAHPDVLELEFEAPEPVRQRAVKELGAALDRELGVPHRITGLAPGTLVPAEALTAQRDILKARYLFAEDEDWDKAVMYF 6slt A 2.7 BS04 AMP A 1 G12 G13 A39 E197 M198 R232 L234 G11 G12 A38 E196 M197 R231 L233 1.14.19.59 0000166,0003824,0004497,0016491 A1E280 31589794 609 DNRIKTVVILGGGTAGWMTAAYLGKALQNTVKIVVLEAPTIPRIGVGEATVPNLQRAFFDYLGIPEEEWMRECNASYKMAVKFINWRTPGEGSPDPRTLDDGHTDTFHHPFGLLPSADQIPLSHYWAAKRLQGETDENFDEACFADTAIMNAKKAPRFLDMRRATNYAWHFDASKVAAFLRNFAVTKQAVEHVEDEMTEVLTDERGFITALRTKSGRILQGDLFVDCSGFRGLLINKAMEEPFIDMSDHLLCNSAVATAVPHDDEKNGVEPYTSSIAMEAGWTWKIPMLGRFGSGHVYSDHFATQDEATLAFSKLWGLDPDNTEFNHVRFRVGRNRRAWVRNCVSVGLASCFVEPLESSGIYFIYAAIHMLAKHFPDKTFDKVLVDRFNREIEEMFDDTRDFLQAHYYFSPRVDTPFWRANKELKLADSIKDKVETYRAGLPVNLPVTDEGTYYGNFEAEFRNFWTNGSYYCIFAGLGLMPRNPLPALAYKPQSIAEAELLFADVKRKGDTLVESLPSTYDLLRQLHG 6sq8 A 2.59 BS02 AMP A 1 G271 A272 Q292 N293 T296 Q297 D377 R392 R407 K483 G263 A264 Q284 N285 T288 Q289 D369 R384 R399 K475 T158 D201 Q297 E298 I398 N403 K483 T154 D193 Q289 E290 I390 N395 K475 ? 0000166,0016874 R4R1U5 32337091 502 PAMGYARRVMDGIGEVAVTGAGGSVTGARLRHQVRLLAHALTEAGIPPGRGVACLHANTWRAIALRLAVQAIGCHYVGLRPTAAVTEQARAIAAADSAALVFEPSVEARAADLLERVSVPVVLSLGPTSRGRDILATPLRYREHPEGIAVVAFTGTPKGVAHSSTAMSACVDAAVSMYGRGPWRFLIPIPLSDLGGELAQCTLATGGTVVLLEEFQPDAVLEAIERERATHVFLAPNWLYQLAEHPALPRSDLSSLRRVVYGGAPAVPSRVAAARERMGAVLMQNYGTQEAAFIAALTPDDHARRELLTAVGRPLPHVEVEIRDDSGGTLPRGAVGEVWVRSPMTMSGYWRDPERTAQVLSGGWLRTGDVGTFDEDGHLHLTDRLQDIIIVEAYNVYSRRVEHVLTEHPDVRAAAVVGVPDPDSGEAVCAAVVVADGADPDPEHLRALVRDHLGDLHVPRRVEFVRSIPVTPAGKPDKVKVRTWFT 6sq8 B 2.59 BS02 AMP B 1 G271 Q292 Q297 D377 R392 R407 K483 G270 Q291 Q296 D376 R391 R406 K482 T158 D201 Q297 E298 I398 N403 K483 T160 D200 Q296 E297 I397 N402 K482 ? 0000166,0016874 R4R1U5 32337091 502 PAMGYARRVMDGIGEVAVTGAGGSVTGARLRHQVRLLAHALTEAGIPPGRGVACLHANTWRAIALRLAVQAIGCHYVGLRPTAAVTEQARAIAAADSAALVFEPSVEARAADLLERVSVPVVLSLGPTSRGRDILAASVPEGTPLRYREHPEGIAVVAFTSGTPKGVAHSSTAMSACVDAAVSMYGRGPWRFLIPIPLSDLGGELAQCTLATGGTVVLLEEFQPDAVLEAIERERATHVFLAPNWLYQLAEHPALPRSDLSSLRRVVYGGAPAVPSRVAAARERMGAVLMQNYGTQEAAFIAALTPDDHARRELLTAVGRPLPHVEVEIRDDSGGTLPRGAVGEVWVRSPMTMSGYWRDPERTAQVLSGGWLRTGDVGTFDEDGHLHLTDRLQDIIIVEAYNVYSRRVEHVLTEHPDVRAAAVVGVPDPDSGEAVCAAVVVADGADPDPEHLRALVRDHLGDLHVPRRVEFVRSIPVTPAGKPDKVKVRTWFTD 6sq8 C 2.59 BS02 AMP C 1 G271 Q292 N293 Q297 D377 R392 R407 K483 G265 Q286 N287 Q291 D371 R386 R401 K477 T158 D201 Q297 E298 I398 N403 K483 T156 D195 Q291 E292 I392 N397 K477 ? 0000166,0016874 R4R1U5 32337091 502 PAMGYARRVMDGIGEVAVTGAGGSVTGARLRHQVRLLAHALTEAGIPPGRGVACLHANTWRAIALRLAVQAIGCHYVGLRPTAAVTEQARAIAAADSAALVFEPSVEARAADLLERVSVPVVLSLGPTSRGRDILAASTPLRYREHPEGIAVVAFTSTPKGVAHSSTAMSACVDAAVSMYGRGPWRFLIPIPLSDLGGELAQCTLATGGTVVLLEEFQPDAVLEAIERERATHVFLAPNWLYQLAEHPALPRSDLSSLRRVVYGGAPAVPSRVAAARERMGAVLMQNYGTQEAAFIAALTPDDHARRELLTAVGRPLPHVEVEIRDDSGGTLPRGAVGEVWVRSPMTMSGYWRDPERTAQVLSGGWLRTGDVGTFDEDGHLHLTDRLQDIIIVEAYNVYSRRVEHVLTEHPDVRAAAVVGVPDPDSGEAVCAAVVVADGADPDPEHLRALVRDHLGDLHVPRRVEFVRSIPVTPAGKPDKVKVRTWFTD 6sq8 D 2.59 BS02 AMP D 1 G271 Q292 N293 T296 Q297 D377 R392 R407 K483 G264 Q285 N286 T289 Q290 D370 R385 R400 K476 T158 D201 Q297 E298 I398 N403 K483 T155 D194 Q290 E291 I391 N396 K476 ? 0000166,0016874 R4R1U5 32337091 502 GPAMGYARRVMDGIGEVAVTGAGGSVTGARLRHQVRLLAHALTEAGIPPGRGVACLHANTWRAIALRLAVQAIGCHYVGLRPTAAVTEQARAIAAADSAALVFEPSVEARAADLLERVSVPVVLSLGPTSRGRDILATPLRYREHPEGIAVVAFTSTPKGVAHSSTAMSACVDAAVSMYGRGPWRFLIPIPLSDLGGELAQCTLATGGTVVLLEEFQPDAVLEAIERERATHVFLAPNWLYQLAEHPALPRSDLSSLRRVVYGGAPAVPSRVAAARERMGAVLMQNYGTQEAAFIAALTPDDHARRELLTAVGRPLPHVEVEIRDDSGGTLPRGAVGEVWVRSPMTMSGYWRDPERTAQVLSGGWLRTGDVGTFDEDGHLHLTDRLQDIIIVEAYNVYSRRVEHVLTEHPDVRAAAVVGVPDPDSGEAVCAAVVVADGADPDPEHLRALVRDHLGDLHVPRRVEFVRSIPVTPAGKPDKVKVRTWFT 6sq8 E 2.59 BS02 AMP E 1 G271 A272 P273 Q292 Y294 T296 D377 N403 G270 A271 P272 Q291 Y293 T295 D376 N402 T158 D201 Q297 E298 I398 N403 K483 T157 D200 Q296 E297 I397 N402 K482 ? 0000166,0016874 R4R1U5 32337091 502 MGYARRVMDGIGEVAVTGAGGSVTGARLRHQVRLLAHALTEAGIPPGRGVACLHANTWRAIALRLAVQAIGCHYVGLRPTAAVTEQARAIAAADSAALVFEPSVEARAADLLERVSVPVVLSLGPTSRGRDIAASVPEGTPLRYREHPEGIAVVAFTSGTTGTPKGVAHSSTAMSACVDAAVSMYGRGPWRFLIPIPLSDLGGELAQCTLATGGTVVLLEEFQPDAVLEAIERERATHVFLAPNWLYQLAEHPALPRSDLSSLRRVVYGGAPAVPSRVAAARERMGAVLMQNYGTQEAAFIAALTPDDHARRELLTAVGRPLPHVEVEIRDDSGGTLPRGAVGEVWVRSPMTMSGYWRDPERTAQVLSGGWLRTGDVGTFDEDGHLHLTDRLQDIIIVEAYNVYSRRVEHVLTEHPDVRAAAVVGVPDPDSGEAVCAAVVVADGADPDPEHLRALVRDHLGDLHVPRRVEFVRSIPVTPAGKPDKVKVRTWFTD 6sy7 A 2.75 BS01 AMP A 1 A288 Q289 A290 R312 I450 A269 Q270 A271 R293 I418 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G88 R154 G155 D180 G181 K207 T208 D210 D212 R255 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 -logKd/Ki=3.33, Kd=0.47mM O15648 31838765 503 MLNSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWGLIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 A 2.75 BS02 AMP B 1 R117 S118 L121 R155 R98 S99 L102 R136 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G88 R154 G155 D180 G181 K207 T208 D210 D212 R255 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 -logKd/Ki=3.33, Kd=0.47mM O15648 31838765 1001 MLNSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWGLIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 B 2.75 BS01 AMP A 1 R117 S118 L121 R155 R97 S98 L101 R135 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G87 R153 G154 D179 G180 K206 T207 D209 D211 R254 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 503 LNSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWGLIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 B 2.75 BS02 AMP B 1 A288 Q289 A290 R312 I450 A268 Q269 A270 R292 I417 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G87 R153 G154 D179 G180 K206 T207 D209 D211 R254 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 1001 LNSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWGLIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 C 2.75 BS01 AMP C 1 A288 Q289 A290 R312 I450 A265 Q266 A267 R289 I414 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G84 R150 G151 D176 G177 K203 T204 D206 D208 R251 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 503 SVTQEDLKVDRLPGADYPNPSKKYSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWGLIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 C 2.75 BS02 AMP D 1 R117 S118 L121 N125 R155 R94 S95 L98 N102 R132 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G84 R150 G151 D176 G177 K203 T204 D206 D208 R251 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 1001 SVTQEDLKVDRLPGADYPNPSKKYSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWGLIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 D 2.75 BS01 AMP C 1 R117 S118 L121 N125 R155 R96 S97 L100 N104 R134 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G86 R152 G153 D178 G179 K205 T206 D208 D210 R253 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 503 NSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWGIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 D 2.75 BS02 AMP D 1 A288 Q289 A290 R312 I450 A267 Q268 A269 R291 I415 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G86 R152 G153 D178 G179 K205 T206 D208 D210 R253 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 1001 NSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWGIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 E 2.75 BS01 AMP F 1 R117 S118 L121 N125 R155 R95 S96 L99 N103 R133 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G85 R151 G152 D177 G178 K204 T205 D207 D209 R252 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 1001 SVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWLIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAK 6sy7 E 2.75 BS02 AMP F 2 A288 Q289 A290 R312 I450 A266 Q267 A268 R290 I414 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G85 R151 G152 D177 G178 K204 T205 D207 D209 R252 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 1002 SVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWLIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAK 6sy7 F 2.75 BS01 AMP F 1 A288 Q289 A290 R312 I450 A266 Q267 A268 R290 I413 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G85 R151 G152 D177 G178 K204 T205 D207 D209 R252 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 1001 SVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 F 2.75 BS02 AMP F 2 R117 S118 L121 R155 R95 S96 L99 R133 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G85 R151 G152 D177 G178 K204 T205 D207 D209 R252 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 1002 SVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 G 2.75 BS01 AMP G 1 A288 Q289 A290 R312 I450 A267 Q268 A269 R291 I415 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G86 R152 G153 D178 G179 K205 T206 D208 D210 R253 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 503 NSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWLIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 G 2.75 BS02 AMP H 1 R117 S118 L121 N125 R155 R96 S97 L100 N104 R134 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G86 R152 G153 D178 G179 K205 T206 D208 D210 R253 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 1001 NSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWLIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 H 2.75 BS01 AMP G 1 R117 S118 R155 R98 S99 R136 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G88 R154 G155 D180 G181 K207 T208 D210 D212 R255 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 503 MLNSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWLIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6sy7 H 2.75 BS02 AMP H 1 A288 Q289 A290 R312 I450 A269 Q270 A271 R293 I417 G107 R173 G174 D199 G200 K226 T227 D229 D231 R274 G88 R154 G155 D180 G181 K207 T208 D210 D212 R255 2.7.1.11 0003872,0005524,0005737,0006002,0006096,0016301,0016310,0020015,0042301,0046872,0061615 O15648 31838765 1001 MLNSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIMYNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSITLTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKEMVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFGFQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPISEQEVMSLLERRFCHSRSCVIIVAEGFGQDWLIDIGVILTEKVKAFLKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHNNYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRLHEELAKL 6tm4 BBB 1.89 BS01 AMP BBB 1 S88 A212 E213 P214 E234 E235 G237 S238 T239 D299 V319 S89 A213 E214 P215 E235 E236 G238 S239 T240 D300 V320 ? 0000166,0016874,0046872 A0A022MRT4 31903677 501 AMSRSRPELGDWSSPAELAELQRSQLPRVLAQALRSPFYAARYRGTTPPRTADDFAGVEVTAKQDLRDQYPFGMLAVGREHLATYHESSGTAGEPTASYYTEEDWTDLAERFARKWTGIHPSDTFLVRTPYGLVITGHLAQAAGRLRGATVVPGDARSLATPLSRMVRVLKTLDVTLTWCNPTEITMLAAAAKAAGLRPDQDFPHLRAMFTAAEPLTEVRRRRLSEIWGGIPVVEEYGSTETGTIAGQCPEGRMHLWADRAIFEVYDPRTGTLSEAGRGQMVVTPLYRDAMPLLRYNLADDVEVSTDPCGCGWLLPTVTVLGHRIGPATVTQQRLEELVFSLPAAYEVMFWRAKAHPDVLELEFEAPEPVRQRAVKELGAALDRELGVPHRITGLAPGTLVPAEALTAQRDILKARYLFAEDEDWDKAVMYF 6u7b C 2.09 BS02 AMP C 1 S58 K63 L155 H162 F203 N270 S57 K62 L154 H161 F202 N269 2.7.7.-,2.7.7.85 0001730,0003725,0005524,0005829,0009117,0016020,0016779,0046872,0051607,0060700,0106408 D7Y2H2 31932165 402 STEHVDHKTIARFAEDKVNLPKVKADDFREQAKRLQNKLEGYLSDHPDFSLKRMIPSGSLAKGTALRSLNDIDVAVYISGSDAPQDLRGLLDYLADRLRKAFPNFSPDQVKPQTYSVTVSFRGSGLDVDIVPVLYSGLPDWRGHLISQEDGSFLETSIPLHLDFIKARKRAAPKHFAQVVRLAKYWARLMKQERPNFRFKSFMIELILAKLLDNGVDFSNYPEALQAFFSYLVSTELRERIVFEDNYPASKIGTLSDLVQIIDPVNPVNNVARLYTQSNVDAIIDAAMDAGDAIDAAFYAPTKQLTVTYWQKVFGSSFQG 6v89 A 2.45 BS01 AMP A 1 G181 G183 R184 Y203 D204 P205 Y206 C237 N243 G156 G158 R159 Y178 D179 P180 Y181 C212 N218 1.1.1.- 0003714,0016616,0051287 Q13363 33524397 501 HMPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLT 6v8a A 2.35 BS01 AMP A 1 G181 G183 R184 Y203 D204 Y206 C237 N243 G156 G158 R159 Y178 D179 Y181 C212 N218 1.1.1.- 0003714,0016616,0051287 Q13363 33524397 402 HMPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRTGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLT 6vef A 4.08 BS01 AMP A 1 H313 R337 S530 F531 W533 R710 M711 H229 R253 S441 F442 W444 R621 M622 1.2.4.2 0000166,0000287,0004591,0005515,0005737,0005829,0006099,0016491,0016624,0030976,0042802,0045252 P0AFG3 1001 DTNVKQVKVLQLINAYRFRGHQHANLDPLGLYQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYMTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGHMSVHQKQQQDLVNDALNVE 6vef B 4.08 BS03 AMP B 1 H313 R337 S530 F531 W533 R710 M711 H229 R253 S441 F442 W444 R621 M622 1.2.4.2 0000166,0000287,0004591,0005515,0005737,0005829,0006099,0016491,0016624,0030976,0042802,0045252 P0AFG3 1002 DTNVKQVKVLQLINAYRFRGHQHANLDPLGLYQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYMTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGHMSVHQKQQQDLVNDALNVE 6vpm A 1.58 BS01 AMP A 1 G140 K162 E211 Y212 A213 L263 G32 K54 E103 Y104 A105 L155 D256 K258 E260 N261 D274 T292 D148 K150 E152 N153 D166 T180 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 O14965,Q9ULW0 32694171 602 MSYSYDAPSDFINFSSKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 6vpm B 1.58 BS03 AMP B 1 G140 A160 K162 E211 A213 G32 A52 K54 E103 A105 D256 K258 E260 N261 D274 T292 D148 K150 E152 N153 D166 T180 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 O14965,Q9ULW0 32694171 601 MSYSYDAPSDFINFSSKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 6vt1 A 2.381 BS01 AMP A 1 T145 T168 K170 L171 S175 R190 E227 F248 V315 K317 K326 T145 T168 K170 L171 S175 R190 E227 F248 V315 K317 K326 ? 0005524,0046872 D2W2Z5 32315072 401 MGVRKLATIRTAGEITPIAGAEAIECCHVDGWTCVIKKGEFKQGDRGVYFEIDSFIKEDNDRYPMLSKQVIDYEGQRGTRLRTARLRGQLSQGLFLPMDRFPELASNQVGDDVTEILGITKWEPPISTNLSGEILGEFPTFISKTDQERVQNLIPQIEENKGQKFEVTVKLAGSSMTVYRKDDHIGVCGRNWELRETATNAQWHAARRNKMIEGLQFLNRNLALQGEIIGESIQGNLEKLKGQDFYLFDIYDIDKAQYLTPIERQSLVKQLNDNGFTVKHVPILDDLELNHTAEQILAMADGPSLNKNVKREGLVFKRLDGKFSFKAISNAYLEKHKDR 6vt1 B 2.381 BS01 AMP B 1 T145 T168 K170 L171 S175 E227 F248 V315 K317 K326 T145 T168 K170 L171 S175 E227 F248 V315 K317 K326 ? 0005524,0046872 D2W2Z5 32315072 401 MGVRKLATIRTAGEITPIAGAEAIECCHVDGWTCVIKKGEFKQGDRGVYFEIDSFIKEDNDRYPMLSKQVIDYEGQRGTRLRTARLRGQLSQGLFLPMDRFPELASNQVGDDVTEILGITKWEPPISTNLSGEILGEFPTFISKTDQERVQNLIPQIEENKGQKFEVTVKLAGSSMTVYRKDDHIGVCGRNWELRETATNAQWHAARRNKMIEGLQFLNRNLALQGEIIGESIQGNLEKLKGQDFYLFDIYDIDKAQYLTPIERQSLVKQLNDNGFTVKHVPILDDLELNHTAEQILAMADGPSLNKNVKREGLVFKRLDGKFSFKAISNAYLEKHKDR 6vt1 C 2.381 BS01 AMP C 1 T145 K170 L171 S175 E227 F248 V281 V315 K326 T145 K170 L171 S175 E227 F248 V281 V315 K326 ? 0005524,0046872 D2W2Z5 32315072 401 MGVRKLATIRTAGEITPIAGAEAIECCHVDGWTCVIKKGEFKQGDRGVYFEIDSFIKEDNDRYPMLSKQVIDYEGQRGTRLRTARLRGQLSQGLFLPMDRFPELASNQVGDDVTEILGITKWEPPISTNLSGEILGEFPTFISKTDQERVQNLIPQIEENKGQKFEVTVKLAGSSMTVYRKDDHIGVCGRNWELRETATNAQWHAARRNKMIEGLQFLNRNLALQGEIIGESIQGNLEKLKGQDFYLFDIYDIDKAQYLTPIERQSLVKQLNDNGFTVKHVPILDDLELNHTAEQILAMADGPSLNKNVKREGLVFKRLDGKFSFKAISNAYLEKHKDR 6vt1 D 2.381 BS01 AMP D 1 T145 K170 L171 E227 F248 V315 K317 K326 T145 K170 L171 E227 F248 V315 K317 K326 ? 0005524,0046872 D2W2Z5 32315072 401 MGVRKLATIRTAGEITPIAGAEAIECCHVDGWTCVIKKGEFKQGDRGVYFEIDSFIKEDNDRYPMLSKQVIDYEGQRGTRLRTARLRGQLSQGLFLPMDRFPELASNQVGDDVTEILGITKWEPPISTNLSGEILGEFPTFISKTDQERVQNLIPQIEENKGQKFEVTVKLAGSSMTVYRKDDHIGVCGRNWELRETATNAQWHAARRNKMIEGLQFLNRNLALQGEIIGESIQGNLEKLKGQDFYLFDIYDIDKAQYLTPIERQSLVKQLNDNGFTVKHVPILDDLELNHTAEQILAMADGPSLNKNVKREGLVFKRLDGKFSFKAISNAYLEKHKDR 6vt8 A 1.998 BS01 AMP A 1 T145 T168 K170 L171 S175 E227 F248 V315 K317 K326 T142 T165 K167 L168 S172 E224 F245 V312 K314 K323 ? 0005524,0046872 D2W2Z5 32315072 401 RKLATIRTAGEITPIAGAEAIECCHVDGWTCVIKKGEFKQGDRGVYFEIDSFIKEDNDRYPMLSKQVIDYEGQRGTRLRTARLRGQLSQGLFLPMDRFPELASNQVGDDVTEILGITKWEPPISTNLSGEILGEFPTFISKTDQERVQNLIPQIEENKGQKFEVTVKLDGSSMTVYRKDDHIGVCGRNWELRETATNAQWHAARRNKMIEGLQFLNRNLALQGEIIGESIQGNLEKLKGQDFYLFDIYDIDKAQYLTPIERQSLVKQLNDNGFTVKHVPILDDLELNHTAEQILAMADGPSLNKNVKRAGLVFKRLDGKFSFKAISNAYLEKHKDR 6vte A 2.1 BS01 AMP A 1 T145 T168 M170 L171 S175 E227 F248 V315 K317 K326 T142 T165 M167 L168 S172 E224 F245 V312 K314 K323 ? 0005524,0046872 D2W2Z5 32315072 401 RKLATIRTAGEITPIAGAEAIECCHVDGWTCVIKKGEFKQGDRGVYFEIDSFIKEDNDRYPMLSKQVIDYEGQRGTRLRTARLRGQLSQGLFLPMDRFPELASNQVGDDVTEILGITKWEPPISTNLSGEILGEFPTFISKTDQERVQNLIPQIEENKGQKFEVTVMLDGSSMTVYRKDDHIGVCGRNWELRETATNAQWHAARRNKMIEGLQFLNRNLALQGEIIGESIQGNLEKLKGQDFYLFDIYDIDKAQYLTPIERQSLVKQLNDNGFTVKHVPILDDLELNHTAEQILAMADGPSLNKNVKREGLVFKRLDGKFSFKAISNAYLEKHKDR 6vvg A 2.01 BS01 AMP A 1 V34 V47 K49 D92 Y93 S95 L148 D160 V28 V41 K43 D86 Y87 S89 L142 D154 D141 K143 N146 D160 T169 D135 K137 N140 D154 T163 ? 0000166,0004672,0004674,0005524,0006468 A0A097P1P8 33579933 301 PSKSISRVAQELSKYEILKKLDESYSSVYLCKKKGEHKRFVCKIVKPSTFNSLEFDVHILMRNNPNFIKLHNFVFNDNGESLLIMDYVSDGDLFDFVKMNDTRELRLNEAACKKIIITLVTALNDLHKNNIVHNDVKLENLLYDRKKKRLFVCDYGLSRIVGTPSFYDGTTVYFSPEKIRHEAYQTSFDWWAVGVVAYEILSTEYPFDINMDAIEPKDMLPLYSKPLPTIEHVSKKANDFVRRMLALDINSRLSTYDEIIKHPFLCF 6vvg B 2.01 BS01 AMP B 1 V47 K49 M91 D92 Y93 V94 S95 L148 D160 V40 K42 M84 D85 Y86 V87 S88 L134 D146 D141 K143 N146 D160 T169 D127 K129 N132 D146 T155 ? 0000166,0004672,0004674,0005524,0006468 A0A097P1P8 33579933 301 PSKSISRVAQELSKYEILKKLDESSSVYLCKKKGEHKRFVCKIVKPSTFNSLEFDVHILMRNNPNFIKLHNFVFNDNGESLLIMDYVSDGDLFDFVKRLNEAACKKIIITLVTALNDLHKNNIVHNDVKLENLLYDRKKKRLFVCDYGLSRIVGTPSFYDGTTVYFSPEKIRHEAYQTSFDWWAVGVVAYEILSTEYPFDINEDNEEEMDAIEPKDMLPLYSKPLPTIEHVSKKANDFVRRMLALDINSRLSTYDEIIKHPFLC 6w6y A 1.451 BS01 AMP A 1 D22 I23 V49 L126 A129 G130 I131 A154 F156 D20 I21 V47 L124 A127 G128 I129 A152 F154 2.1.1.56,2.1.1.57,2.7.7.48,2.7.7.50,3.1.13.-,3.4.19.12,3.4.22.-,3.4.22.69,3.6.4.12,3.6.4.13,4.6.1.- P0DTD1 32939273 201 VNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLE 6wbo A 2.65 BS01 AMP A 1 I259 K260 R265 E310 F350 M412 K414 W429 K431 K433 I249 K250 R255 E300 F340 M402 K404 W419 K421 K423 6.5.1.6 0003677,0003909,0003910,0005524,0006260,0006266,0006273,0006281,0006310,0016874,0046872,0051301,0071897 C5A7K8 602 HMRYSELAELYRRLEKTTLKTLKTKFVADFLKKTPDDLLEIVPYLILGKVFPDWDERELGVGEKLLIKAVSMATGVPEKEIENSIKDTGDLGESVALALKKRRQKSFFSQPLTIKRVYNTFVKVAEASGEGSQDRKMKYLANLFMDAGPEEGKYIARTVLGTMRTGVAEGILRDAIAEAFKVKVELVERAYMLTSDFGYVAKIAKLEGNEGLSKVSIQIGKPIRPMLAQNAASVKDALIEMGGEAAFEIKYDGARVQVHRDGDKVIIYSRRLENVTRSIPEIVEAVKASLKPSKVIVEGELVAVGENGRPRPFQYVLRRFRRKYNIEEMIEKIPLELNLFDILYVNGESLIDTKFTERRKRLEESVEESDKIKLAEQLVTKKVDEAEEFYKRALELGHEGLMAKRLDAIYEPGNRGKKWLKIKPTMENLDLVIIGAEWGEGRRAHLLGSFLVGAYDPESGEFVPVGKVGSGFTDEDLVEFTKMLKPLIIREEGKFVEIEPKVVIEVTYQEIQKSPKYKSGFALRFPRYVALRENKSPEEADTIERVAQLYELQER 6wfj AcA 2.5 BS04 AMP AcA 1 T256 F257 K295 Y340 Y371 D376 H535 T152 F153 K191 Y236 Y267 D272 H431 3.1.4.1,3.6.1.9 0003676,0004115,0004527,0004528,0004551,0005044,0005158,0005509,0005515,0005524,0005576,0005615,0005765,0005886,0006091,0006796,0006955,0008270,0009143,0009986,0010035,0010467,0016020,0016192,0016323,0016787,0016788,0016791,0030247,0030282,0030308,0030318,0030500,0030502,0030505,0030643,0030730,0031214,0031953,0032869,0033198,0036219,0036221,0042803,0045599,0045719,0046034,0046325,0046627,0046872,0047429,0047693,0050427,0050656,0055062,0090304,0106177,0110148,1990787 P22413 32876064 1006 VKSCKGRCFERTFGNCRCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINYSSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVYTPKHPKEVHPLVQCPFTRNPRDNLGCSCNPSILPIEDFQTQFNLTVAEEKIIKHETLPYGRPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPLSPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTLLRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCENLDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFYQQRKEPVSDILKLKTHLPTF 6wfj BcB 2.5 BS04 AMP BcB 1 T256 F257 K295 Y340 Y371 D376 H535 T153 F154 K192 Y237 Y268 D273 H432 3.1.4.1,3.6.1.9 0003676,0004115,0004527,0004528,0004551,0005044,0005158,0005509,0005515,0005524,0005576,0005615,0005765,0005886,0006091,0006796,0006955,0008270,0009143,0009986,0010035,0010467,0016020,0016192,0016323,0016787,0016788,0016791,0030247,0030282,0030308,0030318,0030500,0030502,0030505,0030643,0030730,0031214,0031953,0032869,0033198,0036219,0036221,0042803,0045599,0045719,0046034,0046325,0046627,0046872,0047429,0047693,0050427,0050656,0055062,0090304,0106177,0110148,1990787 P22413 32876064 1006 EVKSCKGRCFERTFGNCRCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINYSSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVYTPKHPKEVHPLVPRDNLGCSCNPSILPIELTVAEEKIIKHETLPYGRPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPLSPVHKCSFYKNNTKVSYGFLSPPQLNKSGIYSEALLTTNIVPMYQSFQVIWRYFHDTLLRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNILIPTHFFIVLTSCKDTSQTPLHCENLDTLAFILPHRTDNSESCVHSSWVEELLMLHRARITDVEHITGLSFYQQRKEPVSDILKLKTHLPTF 6x7u C 2.7 BS02 AMP C 1 H24 R50 G56 F57 G59 F61 I164 Q170 H5 R31 G37 F38 G40 F42 I145 Q151 3.6.1.62,3.6.1.64 0000166,0000287,0003723,0003729,0005634,0005654,0005730,0005737,0006402,0008235,0009117,0016077,0016787,0030145,0030515,0031404,0035863,0035870,0042802,0042803,0046872,0050897,0090068,0097383,0110153,0110155,0140933,1990003,1990174,2000233 Q96DE0 32432673 201 RHACHALLYAPDPGMLFGRIPLRYAILMQMRFDGRLGFPGGFVDTQDRSLEDGLNRELREELGEAAAAFRVERTDYRSSHVGSGPRVVAHFYAKRLTLEELLAVEAGATRAKDHGLEVLGLVRVPLYTLRDGVGGLPTFLENSFIGSAREQLLEALQDLGL 6xhe A 1.88 BS01 AMP A 1 C65 N67 Q69 A109 V118 H119 C65 N67 Q69 A109 V118 H119 H12 K41 H119 H12 K41 H119 4.6.1.18 0003676,0004519,0004522,0004540,0005515,0005576,0016829,0050830 P61823 32757352 201 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 6yc7 B 1.8 BS02 AMP B 1 G27 T29 E62 V63 I64 G27 T29 E55 V56 I57 ? 0000166,0005524,0005829,0006808,0030234 H7C694 33645536 202 MKLITAIVKPFTLTDIKDALEQAGVQGMTVTETQGFHTEVYREYAVDFVPKVKIEVIISDAQAEEVINIIVETARTGKVGDGKVWMTNIEELVRVRTGERGEAAL 6yc7 C 1.8 BS01 AMP B 1 I7 G35 F36 K58 G87 G89 I7 G35 F36 K42 G71 G73 ? 0000166,0005524,0005829,0006808,0030234 H7C694 33645536 202 MKLITAIVKPFTLTDIKDALEQAGVQGMTVTETQGFVDFVPKVKIEVIISDAQAEEVINIIVETARTGKVGDGKVWMTNIEELVRVRTGERGEAAL 6yj7 A 1.64 BS01 AMP A 1 K23 V24 A25 Y45 T46 A47 F115 I128 K21 V22 A23 Y43 T44 A45 F113 I126 ? O31698 201 SLQSDQLLEATVGQFMIEADKVAHVQVGNNLEHALLVLTKTGYTAIPVLDPSYRLHGLIGTNMIMNSIFGLERIEFEKLDQITVEEVMLTDIPRLHINDPIMKGFGMVINNGFVCVENDEQVFEGIFTRRVVLKELNKHIRS 6yj7 B 1.64 BS01 AMP B 1 V24 A25 Y45 T46 A47 F115 I128 R132 V14 A15 Y35 T36 A37 F105 I118 R122 ? O31698 201 EATVGQFMIEADKVAHVQVGNNLEHALLVLTKTGYTAIPVLDPSYRLHGLIGTNMIMNSIFGLERIEFEKLDQITVEEVMLTDIPRLHINDPIMKGFGMVINNGFVCVENDEQVFEGIFTRRVVLKELNKHIRS 6z81 C 2.31 BS01 AMP C 1 R32 H34 T35 S67 T69 R32 H34 T35 S67 T69 ? 0000408,0002949,0005515,0005737,0005829,0008033,0008237,0042802,1990145 P76256 33524148 302 MRILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQDILTTSGTSLTDINALAYGRGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGAWRKNGATRVLAAIDARMGEVYWAEYQRDENGIWHGEETEAVLKPEIVHERMQQLSGEWVTVGTGWQAWPDLGKESGLVLRDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYLRNNVAWKKLPG 6z81 D 2.31 BS01 AMP D 1 H34 S67 T69 H34 S67 T69 ? 0000408,0002949,0005515,0005737,0005829,0008033,0008237,0042802,1990145 P76256 33524148 302 MRILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQDILTTSGTSLTDINALAYGRGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGAWRKNGATRVLAAIDARMGEVYWAEYQRDENGIWHGEETEAVLKPEIVHERMQQLSGEWVTVGTGWQAWPDLGKESGLVLRDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYLRNNVAWKKLP 6zka k 2.5 BS01 AMP k 1 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkb k 2.9 BS01 AMP k 1 I31 S36 E53 Y83 Q97 L100 R104 F134 I31 S36 E53 Y83 Q97 L100 R104 F134 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkc k 3.1 BS01 AMP k 1 I31 S36 E53 Y83 Q97 L100 R104 F134 I31 S36 E53 Y83 Q97 L100 R104 F134 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkd k 2.7 BS01 AMP k 1 I31 S36 E53 Y83 L100 F134 Y198 I31 S36 E53 Y83 L100 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zke k 2.6 BS01 AMP k 1 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkf k 2.8 BS01 AMP k 1 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkg k 3.4 BS01 AMP k 1 I31 S36 E53 Y83 Q97 L100 R104 F134 I31 S36 E53 Y83 Q97 L100 R104 F134 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkh k 3.0 BS01 AMP k 1 I31 S36 E53 Y83 L100 R126 F134 Y198 I31 S36 E53 Y83 L100 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zki k 2.8 BS01 AMP k 1 I31 S36 E53 Y83 L100 R126 F134 Y198 I31 S36 E53 Y83 L100 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkj k 3.0 BS01 AMP k 1 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkk k 3.7 BS01 AMP k 1 I31 S36 E53 Y83 Q97 L100 R104 R126 F134 I31 S36 E53 Y83 Q97 L100 R104 R126 F134 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkl k 3.1 BS01 AMP k 1 I31 S36 E53 L79 Y83 R126 F134 Y198 I31 S36 E53 L79 Y83 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkm k 2.8 BS01 AMP k 1 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkn k 2.9 BS01 AMP k 1 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zko k 3.8 BS01 AMP k 1 I31 S36 E53 Y83 Q97 L100 R104 F134 I31 S36 E53 Y83 Q97 L100 R104 F134 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkp k 3.2 BS01 AMP k 1 I31 S36 E53 Y83 R126 F134 Y198 I31 S36 E53 Y83 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkq k 3.3 BS01 AMP k 1 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkr k 3.5 BS01 AMP k 1 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zks k 3.1 BS01 AMP k 1 I31 S36 E53 L79 Y83 R126 F134 Y198 I31 S36 E53 L79 Y83 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkt k 2.8 BS01 AMP k 1 I31 S36 E53 L79 Y83 L100 R104 R126 F134 Y198 I31 S36 E53 L79 Y83 L100 R104 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zku k 3.0 BS01 AMP k 1 I31 S36 E53 Y83 L100 R126 F134 Y198 I31 S36 E53 Y83 L100 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zkv k 2.9 BS01 AMP k 1 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 I31 S36 E53 L79 Y83 L100 R126 F134 Y198 0006120 32972993 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 6zu5 LH0 2.9 BS02 AMP LH0 1 R23 V42 L43 T44 L56 W57 R23 V42 L43 T44 L56 W57 0003735,0005840,0006412,0019843 33125369 500 MKRLLCEEKVEIPEGCSVEILERVMTVRGKRATAVRDLSHFVLTMDVHEGHVRLRLWNGTNRERSKLITCASVIRNCIVGCMSGYEYTLKVVYKHFPMSVAIEDDGKTVVVKNFLGQKHARRYKMRGDSIARLGTEKDTFVVEGSSLEDVSQSAGTIQENCQVKKIDSRTFLDGIYFLSRNVVG 7ae6 A 1.65 BS01 AMP A 1 F75 P97 N103 Y109 F73 P95 N101 Y107 3.1.27.- 0000166,0004519,0004540,0110001 A0A0B0QJR1 33290744 201 NIEPVIIETRLELIGRYLDHLKKFENISLDDYLSSFEQQLITERLLQLITQAAIDINDHILSKLKSGKSYTNFEAFIELGKYQILTPELAKQIAPSSGLANRLVHEYDDIDPNQVFMAISFALQQYPLYVRQINSYLITLEEENDLE 7ae6 A 1.65 BS02 AMP A 2 P97 L101 R104 D111 I112 D113 Q116 P95 L99 R102 D109 I110 D111 Q114 3.1.27.- 0000166,0004519,0004540,0110001 A0A0B0QJR1 33290744 202 NIEPVIIETRLELIGRYLDHLKKFENISLDDYLSSFEQQLITERLLQLITQAAIDINDHILSKLKSGKSYTNFEAFIELGKYQILTPELAKQIAPSSGLANRLVHEYDDIDPNQVFMAISFALQQYPLYVRQINSYLITLEEENDLE 7ae6 B 1.65 BS01 AMP B 1 F75 P97 N103 Y109 F71 P93 N99 Y105 3.1.27.- 0000166,0004519,0004540,0110001 A0A0B0QJR1 33290744 201 IEPVIIETRLELIGRYLDHLKKFENISLDDYLSSFEQQLITERLLQLITQAAIDINDHILSKLKSKSYTNFEAFIELGKYQILTPELAKQIAPSSGLANRLVHEYDDIDPNQVFMAISFALQQYPLYVRQINSYLITLEEEND 7ae6 B 1.65 BS02 AMP B 2 R104 D113 Q116 R100 D109 Q112 3.1.27.- 0000166,0004519,0004540,0110001 A0A0B0QJR1 33290744 202 IEPVIIETRLELIGRYLDHLKKFENISLDDYLSSFEQQLITERLLQLITQAAIDINDHILSKLKSKSYTNFEAFIELGKYQILTPELAKQIAPSSGLANRLVHEYDDIDPNQVFMAISFALQQYPLYVRQINSYLITLEEEND 7aer A 3.0 BS01 AMP C 1 R76 K106 R68 K98 2.7.7.108 0003674,0003677,0005524,0005575,0008150,0016779,0046872 Q8ECH7 33290744 201 MQQLNENKIIKLLRDNIPKLQLIYLFGSYSDIDIAVLAADTLDNIARWELAQKLASALDSDVDLVDLRSASTVLCQQVVTQGKQLWGTQQDDELFAVKTISMYQHLQAERQAIIDDVMA 7aer B 3.0 BS01 AMP B 1 R70 G95 N98 I99 Y104 Q105 R70 G95 N98 I99 Y104 Q105 3.1.-.- 0000166,0003674,0004519,0004540,0005575,0008150,0110001 Q8ECH6 33290744 201 MNDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNNLITQPLSDNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE 7aer B 3.0 BS02 AMP B 2 K92 L96 I99 E106 L107 N108 I111 K92 L96 I99 E106 L107 N108 I111 3.1.-.- 0000166,0003674,0004519,0004540,0005575,0008150,0110001 Q8ECH6 33290744 202 MNDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNNLITQPLSDNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE 7aer B 3.0 BS03 AMP B 3 K92 D110 H114 H119 K92 D110 H114 H119 3.1.-.- 0000166,0003674,0004519,0004540,0005575,0008150,0110001 Q8ECH6 33290744 203 MNDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNNLITQPLSDNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE 7aer C 3.0 BS01 AMP C 1 N98 Y104 Q105 N97 Y103 Q104 3.1.-.- 0000166,0003674,0004519,0004540,0005575,0008150,0110001 Q8ECH6 33290744 201 NDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNNLITQPLSDNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE 7aer C 3.0 BS02 AMP C 2 K92 G95 L96 Q105 N108 I111 K91 G94 L95 Q104 N107 I110 3.1.-.- 0000166,0003674,0004519,0004540,0005575,0008150,0110001 Q8ECH6 33290744 202 NDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNNLITQPLSDNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE 7aer C 3.0 BS03 AMP C 3 I111 H114 H119 I110 H113 H118 3.1.-.- 0000166,0003674,0004519,0004540,0005575,0008150,0110001 Q8ECH6 33290744 203 NDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNNLITQPLSDNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE 7b7z A 1.7 BS01 AMP B 1 V316 H319 V360 D367 N369 G370 Y399 L403 N407 V214 H217 V258 D265 N267 G268 Y297 L301 N305 2.7.7.108,3.1.4.- Q9BVA6 34408154 600 SLEARAALNQALEMKRQGKREKAQKLFMHALKMDPDFVDALTEFGIFSEEDKDIIQADYLYTRALTISPYHEKALVNRDRTLPLVEEIDQRYFSIIDSKVKKVMSIPKGNSALRRVMEETYYHHIYHTVAIEGNTLTLSEIRHILETRYAVPGKSDEEQNEVIGMHAAMKYINTTLVSRIGSVTISDVLEIHRRVLGYVDPVEAGRFRTTQVLVGHHIPPHPQDVEKQMQEFVQWLNSEEAMNLHPVEFAALAHYKLVYIAPFIDGNGRTSRLLMNLILMQAGYPPITIRKEQRSDYYHVLEAANEGDVRPFIRFIAKCTETTLDTLLFATTEYSVALPE 7b80 A 1.87 BS01 AMP B 1 E234 V316 H319 V360 D367 N369 G370 Y399 L403 N407 E132 V214 H217 V258 D265 N267 G268 Y297 L301 N305 2.7.7.108,3.1.4.- Q9BVA6 34408154 601 SLEARAALNQALEMKRQGKREKAQKLFMHALKMDPDFVDALTEFGIFSEEDKDIIQADYLYTRALTISPYHEKALVNRDRTLPLVEEIDQRYFSIIDSKVKKVMSIPKGNSALRRVMEETYYHHIYHTVAIEGNTLTLSEIRHILETRYAVPGKSDEEQNEVIGMHAAMKYINTTLVSRIGSVTISDVLEIHRRVLGYVDPVEAGRFRTTQVLVGHHIPPHPQDVEKQMQEFVQWLNSEEAMNLHPVEFAALAHYKLVYIAPFIDGNGRTSRLLMNLILMQAGYPPITIRKEQRSDYYHVLEAANEGDVRPFIRFIAKCTETTLDTLLFATTEYSVALPE 7bgn A 2.7 BS03 AMP A 1 L176 R183 S195 W196 T197 Y240 L121 R128 S135 W136 T137 Y180 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 303 AVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLNKLALTSLYALESTISQRKAEVVPSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn A 2.7 BS04 AMP A 2 W107 K109 G110 T112 S113 T141 H143 W60 K62 G63 T65 S66 T94 H96 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 304 AVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLNKLALTSLYALESTISQRKAEVVPSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn A 2.7 BS06 AMP B 1 R263 F264 R203 F204 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 304 AVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLNKLALTSLYALESTISQRKAEVVPSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn B 2.7 BS01 AMP A 1 R263 F264 R204 F205 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 303 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLLNKLALTSLYALESTISQRKAEVPSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn B 2.7 BS05 AMP B 1 R183 S195 W196 T197 Y240 R130 S136 W137 T138 Y181 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 304 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLLNKLALTSLYALESTISQRKAEVPSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn C 2.7 BS03 AMP C 1 R183 S195 W196 T197 Y240 R130 S135 W136 T137 Y180 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 303 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLLNKLALTSLYALESTISQRKAEVSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn C 2.7 BS04 AMP C 2 M78 W107 K109 G110 T112 S113 T141 H143 M32 W61 K63 G64 T66 S67 T95 H97 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 304 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLLNKLALTSLYALESTISQRKAEVSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn C 2.7 BS06 AMP D 1 R263 F264 R203 F204 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 304 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLLNKLALTSLYALESTISQRKAEVSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn D 2.7 BS01 AMP C 1 R263 F264 R202 F203 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 303 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLNKLALTSLYALESTISQRKAEVSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn D 2.7 BS05 AMP D 1 R183 S195 W196 T197 Y240 R129 S134 W135 T136 Y179 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 304 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLNKLALTSLYALESTISQRKAEVSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn D 2.7 BS06 AMP D 2 R103 W107 K109 G110 T112 S113 T141 C142 H143 C149 R57 W61 K63 G64 T66 S67 T95 C96 H97 C103 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 305 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLNKLALTSLYALESTISQRKAEVSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn E 2.7 BS03 AMP E 1 R183 S195 W196 Y240 R128 S133 W134 Y178 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 303 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDNKLALTSLYALESTISQRKAEVSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn E 2.7 BS04 AMP E 2 W107 K109 T112 S113 H143 W61 K63 T66 S67 H97 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 304 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDNKLALTSLYALESTISQRKAEVSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn E 2.7 BS06 AMP F 1 R263 F264 R201 F202 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 304 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDNKLALTSLYALESTISQRKAEVSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn F 2.7 BS01 AMP E 1 R263 F264 R210 F211 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 303 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLLNKLALTSLYALESTISQRKAEVVEENGKPSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn F 2.7 BS05 AMP F 1 R183 S195 T197 Y240 R130 S142 T144 Y187 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 304 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLLNKLALTSLYALESTISQRKAEVVEENGKPSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7bgn F 2.7 BS06 AMP F 2 W107 K109 G110 T112 S113 H143 W61 K63 G64 T66 S67 H97 3.-.-.-,3.5.4.19,3.6.1.31 0000105,0004635,0004636 A0A072U2X9 33958623 305 NAVDSLLDSVKWDNKGLAVAIAQNVDTGAILMQGFANREAVATTISSRKATFYSRSRSSLWTKGETSNNFINVHDVFLDCDRDSIIYLGKPDGPTCHTGAETCYYTPVFDLLNKLALTSLYALESTISQRKAEVVEENGKPSWTKRLLLNDKLLCSKIREEANELCETLENNEDKSRTASEMADVLYHAMVLLALKDVKVEEVLQVLRQRF 7c43 A 2.3 BS04 AMP A 1 D80 E82 A83 M206 T207 D230 D34 E36 A37 M160 T161 D184 ? 0000166,0000175,0003676,0005739,0006139,0008270,0008408,0046872,1990923 Q38DE2 33332555 405 SSMILKYPYRVVDTHEKLKEAVTSLQGARSIALDIEAFCTTDQAKQLGRISLVQACSDAKPVVFLFDVLTLTPDVFVKDMQSLLSDREIRKLFFDCRRDVEALSCQLGVKPEGVLDLQVFFTAIQWKLRSVNRRSGMGYVLKSVAGLTRQEGDSAVQTAMTLGNRPVWDIRPLPDHFLEYAAGDVRHILLLSNYLVGNKDVPVDVVAVERLTAQYVEHYAVGKPVITEADATPAEVNRAWLERYIGPGGGCHFCGAKGHTEAECFKKQNGKAKCSFCGEVGHTARNCFKKHPQLL 7c9q A 1.878 BS01 AMP A 1 V17 E20 G21 T27 G28 E29 L30 K112 Y113 M177 V9 E12 G13 T19 G20 E21 L22 K104 Y105 M169 D68 D74 E97 E98 D118 L120 D121 E280 D60 D66 E89 E90 D110 L112 D113 E272 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 7c9q B 1.878 BS01 AMP B 1 V17 E20 G21 A24 G26 T27 G28 E29 L30 T31 Y113 M177 V9 E12 G13 A16 G18 T19 G20 E21 L22 T23 Y101 M165 D68 D74 E97 E98 D118 L120 D121 E280 D56 D62 E85 E86 D106 L108 D109 E268 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 7c9q C 1.878 BS01 AMP C 1 V17 E20 G21 G26 T27 E29 L30 K112 Y113 M177 V9 E12 G13 G18 T19 E21 L22 K96 Y97 M161 D74 E97 E98 D118 L120 D121 E280 D58 E81 E82 D102 L104 D105 E264 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 7c9q D 1.878 BS01 AMP D 1 V17 E20 G21 G26 T27 E29 L30 K112 Y113 M177 V9 E12 G13 G18 T19 E21 L22 K103 Y104 M168 D68 D74 E97 E98 D118 L120 D121 E280 D59 D65 E88 E89 D109 L111 D112 E271 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTNVGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 7cbb A 2.6 BS01 AMP A 1 D146 R147 S265 R267 R292 H424 Q426 D145 R146 S264 R266 R291 H423 Q425 6.3.2.56 0005524,0009058,0016874,0016881,0019290 Q2G1N1 32880431 601 QNHTAVNTAQAIILRDLVDALLFEDIAGIVSNSEITKENGQTLLIYERETQQIKIPVYFSALNMFRYESSQPITIEGRVSKQPLTAAEFWQTIANMNCDLSHEWEVARVEEGLTTAATQLAKQLSELDLASHPFVMSEQFASLKDRPFHPLAKEKRGLREADYQVYQAELNQSFPLMVAAVKKTHMIHGDTANIDELENLTVPIKEQATDMLNDQGLSIDDYVLFPVHPWQYQHILPNVFATEISEKLVVLLPLKFGDYLSSSSMRSLIDIGAPYNHVKVPFAMQSLGALRLTPTRYMKNGEQAEQLLRQLIEKDEALAKYVMVCDETAWWSYMGQDNDIFKDQLGHLTVQLRKYPEVLAKNDTQQLVSMAALAANDRTLYQMICGKDNISKNDVMTLFEDIAQVFLKVTLSFMQYGALPELHGQNILLSFEDGRVQKCVLRDHDTVRIYKPWLTAHQLSLPKYVVREDTPNTLINEDLETFFAYFQTLAVSVNLYAIIDAIQDLFGVSEHELMSLLKQILKNEVATISWVTTDQLAVRHILFDKQTWPFKQILLPLLYQRMPSGLTTVPNPMVTY 7cbb B 2.6 BS01 AMP B 1 D146 R147 S265 R267 R292 H424 Q426 D145 R146 S264 R266 R291 H423 Q425 6.3.2.56 0005524,0009058,0016874,0016881,0019290 Q2G1N1 32880431 601 QNHTAVNTAQAIILRDLVDALLFEDIAGIVSNSEITKENGQTLLIYERETQQIKIPVYFSALNMFRYESSQPITIEGRVSKQPLTAAEFWQTIANMNCDLSHEWEVARVEEGLTTAATQLAKQLSELDLASHPFVMSEQFASLKDRPFHPLAKEKRGLREADYQVYQAELNQSFPLMVAAVKKTHMIHGDTANIDELENLTVPIKEQATDMLNDQGLSIDDYVLFPVHPWQYQHILPNVFATEISEKLVVLLPLKFGDYLSSSSMRSLIDIGAPYNHVKVPFAMQSLGALRLTPTRYMKNGEQAEQLLRQLIEKDEALAKYVMVCDETAWWSYMGQDNDIFKDQLGHLTVQLRKYPEVLAKNDTQQLVSMAALAANDRTLYQMICGKDNISKNDVMTLFEDIAQVFLKVTLSFMQYGALPELHGQNILLSFEDGRVQKCVLRDHDTVRIYKPWLTAHQLSLPKYVVNTLINEDLETFFAYFQTLAVSVNLYAIIDAIQDLFGVSEHELMSLLKQILKNEVATISWVTTDQLAVRHILFDKQTWPFKQILLPLLYLTTVPNPMVTY 7cu1 B 1.91 BS01 AMP B 1 L11 G12 G13 A39 E197 M198 C228 S229 R232 L234 L10 G11 G12 A38 E196 M197 C227 S228 R231 L233 1.14.19.59 0000166,0003824,0004497,0016491 A1E280 33465708 601 DNRIKTVVILGGGTAGWMTAAYLGKALQNTVKIVVLEAPTIPRIGVGEATVPNLQRAFFDYLGIPEEEWMRECNASYKMAVKFINWRTPGEGSPDPRTLDDGHTDTFHHPFGLLPSADQIPLSHYWAAKRLQGETDENFDEACFADTAIMNAKKAPRFLDMRRATNYAWHFDASKVAAFLRNFAVTKQAVEHVEDEMTEVLTDERGFITALRTKSGRILQGDLFVDCSGFRGLLINKAMEEPFIDMSDHLLCNSAVATAVPHDDEKNGVEPYTSSIAMEAGWTWKIPMLGRFGSGHVYSDHFATQDEATLAFSKLWGLDPDNTEFNHVRFRVGRNRRAWVRNCVSVGLASCFVEPLESSGIYFIYAAIHMLAKHFPDKTFDKVLVDRFNREIEEMFDDTRDFLQAHYYFSPRVDTPFWRANKELKLADSIKDKVETYRAGLPVNLPVTGNFEAEFRNFWTNGSYYCIFAGLGLMPRNPLPALAYKPQSIAEAELLFADVKRKGDTLVESLPSTYDLLRQLHGAS 7cvh A 2.09 BS04 AMP A 1 V18 E21 G22 A25 G27 T28 G29 E30 L31 K113 Y114 M178 V9 E12 G13 A16 G18 T19 G20 E21 L22 K96 Y97 M161 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 404 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 7cvh B 2.09 BS04 AMP B 1 V18 E21 G22 T28 E30 L31 K113 Y114 M178 V9 E12 G13 T19 E21 L22 K96 Y97 M161 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 404 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 7cvh C 2.09 BS04 AMP C 1 V18 E21 G22 A25 G27 T28 E30 L31 K113 Y114 R141 V161 M178 V9 E12 G13 A16 G18 T19 E21 L22 K95 Y96 R123 V143 M160 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 404 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 7cvh D 2.09 BS04 AMP D 1 V18 E21 G22 A25 G27 T28 E30 L31 K113 Y114 M178 V9 E12 G13 A16 G18 T19 E21 L22 K99 Y100 M164 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 605 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 7cyf D 3.15 BS01 AMP D 1 G41 R43 N59 A88 G89 I90 G40 R42 N58 A87 G88 I89 ? 0005886,0006808,0009579,0030234,0031676 P73954 34373447 201 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSRNVRSSGQPNTSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 7cyf D 3.15 BS02 AMP F 1 G31 Y32 T33 L65 G30 Y31 T32 L64 ? 0005886,0006808,0009579,0030234,0031676 P73954 34373447 201 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSRNVRSSGQPNTSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 7cyf E 3.15 BS01 AMP D 1 G31 Y32 T33 L65 G30 Y31 T32 L64 ? 0005886,0006808,0009579,0030234,0031676 P73954 34373447 201 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSRNVRSSGQPNTSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 7cyf E 3.15 BS02 AMP E 1 G41 R43 N59 A88 G89 I90 G40 R42 N58 A87 G88 I89 ? 0005886,0006808,0009579,0030234,0031676 P73954 34373447 201 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSRNVRSSGQPNTSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 7cyf F 3.15 BS01 AMP E 1 G31 Y32 T33 L65 G30 Y31 T32 L64 ? 0005886,0006808,0009579,0030234,0031676 P73954 34373447 201 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSRNVRSSGQPNTSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 7cyf F 3.15 BS02 AMP F 1 G41 R43 N59 A88 G89 I90 G40 R42 N58 A87 G88 I89 ? 0005886,0006808,0009579,0030234,0031676 P73954 34373447 201 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSRNVRSSGQPNTSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 7d2f A 2.6 BS01 AMP A 1 R33 H34 R101 E201 H205 F237 H280 A281 S298 R11 H12 R79 E179 H183 F215 H258 A259 S276 3.1.3.2 0000166,0003993,0016311,0016787,0016791 Q5ZWG6 33450485 401 DKLIFAVDIIRHGDRTPIVALPTVNYQWQEGLGQLTAEGMQQEYKMGVAFRKKYIEESHLLPEHYEYGTIYVRSTDYARTLMSAQSLLMGLYPPGTGPTIPAGTSALPHAFQPIPVFSAPSKYDEVIIQQVDRKEREKLMEQYVFSTREWQQKNNELKDKYPLWSRLTGINIDNLGDLETVGHTLYIHQIHNAPMPEGLASNDIETIINSAEWAFMAQEKPQQIANVYSSKLMTNIADYLNSGSMKKSKLKYVLLSAHATTIASVLSFLGAPLEKSPPYASNVNFSLYDNGANYYTVKITYNGNPVSIPACGGSVCELQQLINLVHDS 7d2f B 2.6 BS01 AMP B 1 R33 H34 R37 R101 E201 H205 A233 F237 H280 A281 R11 H12 R15 R79 E179 H183 A211 F215 H258 A259 3.1.3.2 0000166,0003993,0016311,0016787,0016791 Q5ZWG6 33450485 401 DKLIFAVDIIRHGDRTPIVALPTVNYQWQEGLGQLTAEGMQQEYKMGVAFRKKYIEESHLLPEHYEYGTIYVRSTDYARTLMSAQSLLMGLYPPGTGPTIPAGTSALPHAFQPIPVFSAPSKYDEVIIQQVDRKEREKLMEQYVFSTREWQQKNNELKDKYPLWSRLTGINIDNLGDLETVGHTLYIHQIHNAPMPEGLASNDIETIINSAEWAFMAQEKPQQIANVYSSKLMTNIADYLNSGSMKKSKLKYVLLSAHATTIASVLSFLGAPLEKSPPYASNVNFSLYDNGANYYTVKITYNGNPVSIPACGGSVCELQQLINLVH 7dk8 A 1.99 BS01 AMP A 1 S110 I312 M337 A339 S340 S341 Y360 D416 F432 R435 S88 I289 M314 A316 S317 S318 Y337 D385 F401 R404 6.3.2.- 0005737,0006952,0009555,0009851,0010279,0016208,0016874,0016881,0140964,1900424 A3BLS0 33272567 601 EKLRFIDEMTTNVDAVQERVLGEILGRNAGTEYLTKCGLDGATDRAAFRAKVPVVSYDDLQPYIQRIANGDRSPILSTHPVSEFLTSSGTSAGERKLMPTIMDELDRRQLLYSLLMPVMNLYVPGLDKGKGLYFLFVKSETKTPGGLTARPVLTSYYKSDHFKNRPDPYHNYTSPTAAILCADAFQSMYAQMVCGLCQRNDVLRLGAVFASGLLRAIRFLQLNWEQLADDIESGELTPRVTDPSVREAVAAILLPDPELAKLIRAECSKGDWAGIITRVWPNTKYLDVIVTGAMAQYIPTLEFYSGGLPMACTMYASSECYFGLNLRPMCDPSEVSYTIMPNMGYFEFLPVDATQLVDLARVEVGREYELVITTYAGLNRYRVGDVLRVTGFHNAAPQFRFVRRKNVLLSIESDKTDEAELQRAVERASALLRPHGASVVEYTSQACTKRIPGHYVIYWELLTVVDADTLGRCCLEMEEALNTVYRQSRVADGSIGPLEIRVVRPGTFEELMDYAISRGASINQYKVPRCVTFPPIVELLDSRVVSSHFSPALPHWTP 7egk B 2.7 BS01 AMP F 1 G31 Y32 T33 L65 G30 Y31 T32 L64 ? 0005886,0006808,0009579,0030234,0031676 P73954 34031249 200 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSRNVRSSGQPNTSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 7egk B 2.7 BS02 AMP B 1 K40 G41 S42 R43 N59 A88 G89 K39 G40 S41 R42 N58 A87 G88 ? 0005886,0006808,0009579,0030234,0031676 P73954 34031249 201 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSRNVRSSGQPNTSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 7egk D 2.7 BS01 AMP D 1 K40 G41 S42 R43 N59 A88 G89 K39 G40 S41 R42 N58 A87 G88 ? 0005886,0006808,0009579,0030234,0031676 P73954 34031249 201 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSRNVRSSGQPNTSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 7egk D 2.7 BS02 AMP B 1 G31 Y32 T33 L65 G30 Y31 T32 L64 ? 0005886,0006808,0009579,0030234,0031676 P73954 34031249 201 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSRNVRSSGQPNTSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 7egk F 2.7 BS01 AMP D 1 G31 Y32 T33 L65 G30 Y31 T32 L64 ? 0005886,0006808,0009579,0030234,0031676 P73954 34031249 201 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSRNVRSSGQPNTSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 7egk F 2.7 BS02 AMP F 1 K40 G41 S42 R43 N59 A88 G89 K39 G40 S41 R42 N58 A87 G88 ? 0005886,0006808,0009579,0030234,0031676 P73954 34031249 200 AKPANKLVIVTEKILLKKIAKIIDESGAKGYTVMNTGGKGSRNVRSSGQPNTSDIEANIKFEILTETREMAEEIADRVAVKYFNDYAGIIYICSAEVLYGHTFCGPEGC 7emy A 2.97 BS03 AMP A 1 G814 D815 W816 L838 G839 G840 A841 T842 Y865 D927 F939 Q946 K948 R953 G808 D809 W810 L832 G833 G834 A835 T836 Y859 D921 F933 Q940 K942 R947 6.2.1.69 0003824,0005737,0009239,0009366,0016874,0017000,0031177,0043041,0047527 G3XCV2 35105906 1504 SRTALRDWLTEQLADLLGEPLADVRALADDDDLLGCGLDSIRLMYLQERLRARGSTLDFAQLAQRPCLGAWLDLLACADRLSAPATVALPTAQDRDQPFELSSVQQAYWLGRGAGEVLGNVSCHAFLEFRTRDVDPQRLAAAAECVRQRHPMLRARFLDGRQQILPTPPLSCFDLQDWRTLQVDEAERDWQALRDWRAHECLAVERGQVFLLGLVRMPGGEDRLWLSLDLLAADVESLRLLLAELGVAYLAPERLAEPPALHFADYLAHRAAQRAEAAARARDYWLERLPRLPDAPALPLACAPESIRQPRTRRLAFQLSAGESRRLERLAAQHGVTLSSVFGCAFALVLARWSESAEFLLNVPLFDRHADDPRIGEVIADFTTLLLLECRMQAGVSFAEAVKSFQRNLHGAIDHAAFPALEVLREARRQGQPRSAPVVFASNLGEEGFVPAAFRDAFGDLHDMLSQTPQVWLDHQLYRVGDGILLAWDSVVGLFPEGLPETMFEAYVGLLQRLCDSAWGQPADLPLPWAQQARRALLNGQPACATARTLHRDFFLRAAEAPDADALLYRDQRVTRGELAERALRIAGGLREAGVRPGDAVEVSLPRGPQQVAAVFGVLAAGACYVPLDIDQPPARRRLIEEAAGVCLAITEEDDPQALPPRLDVQRLLRGPALAAPVPLAPQASAYVIYTSGSTGVPKGVEVSHAAAINTIDALLDLLRVNASDRLLAVSALDFDLSVFDLFGGLGAGASLVLPAQEQARDAAAWAEAIQRHAVSLWNSAPALLEMALSLPASQADYRSLRAVLLSGDWVALDLPGRLRPRCAEGCRLHVLGGATEAGIWSNLQSVDTVPPHWRSIPYGRPLPGQAYRVVDTHGRDVPDLVVGELWIGGASLARGYRNDPELSARRFVHDAQGRWYRTGDRGRYWGDGTLEFLGRVDQQVKVRGQRIELGEVEAALCAQAGVESACAAVLGGGVASLGAVLVPRLAPRAEGSMDLPAAQPFAGLAEAEAVLTREILGALLEAPLELDDGLRRRWLDWLADSAASALPSLDEALRRLGWQAAGLTAMGNALRGLLAGEQAPAALLLDPWLAPQAVAARLPDGREALARLLEALPTPAAGERLRVAVLDTRAGLWLDQGMASLLRPGLELTLFERSRVLLDAAATRLPERIVVQALDDGLLPAEHLGRYDRVISFAALHAYEASREGLALAAALLRPQGRLLLVDLLCESPLALLGAALLDDRPLRLAELPSLLADLAAAGLAPRCLWRSERIALVEALAPGLGLDAAALQAGLEQRLPQAMRPERLWCLPSLPLNGNGKVDRRRLAESMTRALG 7emy B 2.97 BS03 AMP B 1 G814 D815 W816 L838 G839 G840 A841 T842 Y865 D927 F939 Q946 K948 R953 G808 D809 W810 L832 G833 G834 A835 T836 Y859 D921 F933 Q940 K942 R947 6.2.1.69 0003824,0005737,0009239,0009366,0016874,0017000,0031177,0043041,0047527 G3XCV2 35105906 1504 SRTALRDWLTEQLADLLGEPLADVRALADDDDLLGCGLDSIRLMYLQERLRARGSTLDFAQLAQRPCLGAWLDLLACADRLSAPATVALPTAQDRDQPFELSSVQQAYWLGRGAGEVLGNVSCHAFLEFRTRDVDPQRLAAAAECVRQRHPMLRARFLDGRQQILPTPPLSCFDLQDWRTLQVDEAERDWQALRDWRAHECLAVERGQVFLLGLVRMPGGEDRLWLSLDLLAADVESLRLLLAELGVAYLAPERLAEPPALHFADYLAHRAAQRAEAAARARDYWLERLPRLPDAPALPLACAPESIRQPRTRRLAFQLSAGESRRLERLAAQHGVTLSSVFGCAFALVLARWSESAEFLLNVPLFDRHADDPRIGEVIADFTTLLLLECRMQAGVSFAEAVKSFQRNLHGAIDHAAFPALEVLREARRQGQPRSAPVVFASNLGEEGFVPAAFRDAFGDLHDMLSQTPQVWLDHQLYRVGDGILLAWDSVVGLFPEGLPETMFEAYVGLLQRLCDSAWGQPADLPLPWAQQARRALLNGQPACATARTLHRDFFLRAAEAPDADALLYRDQRVTRGELAERALRIAGGLREAGVRPGDAVEVSLPRGPQQVAAVFGVLAAGACYVPLDIDQPPARRRLIEEAAGVCLAITEEDDPQALPPRLDVQRLLRGPALAAPVPLAPQASAYVIYTSGSTGVPKGVEVSHAAAINTIDALLDLLRVNASDRLLAVSALDFDLSVFDLFGGLGAGASLVLPAQEQARDAAAWAEAIQRHAVSLWNSAPALLEMALSLPASQADYRSLRAVLLSGDWVALDLPGRLRPRCAEGCRLHVLGGATEAGIWSNLQSVDTVPPHWRSIPYGRPLPGQAYRVVDTHGRDVPDLVVGELWIGGASLARGYRNDPELSARRFVHDAQGRWYRTGDRGRYWGDGTLEFLGRVDQQVKVRGQRIELGEVEAALCAQAGVESACAAVLGGGVASLGAVLVPRLAPRAEGSMDLPAAQPFAGLAEAEAVLTREILGALLEAPLELDDGLRRRWLDWLADSAASALPSLDEALRRLGWQAAGLTAMGNALRGLLAGEQAPAALLLDPWLAPQAVAARLPDGREALARLLEALPTPAAGERLRVAVLDTRAGLWLDQGMASLLRPGLELTLFERSRVLLDAAATRLPERIVVQALDDGLLPAEHLGRYDRVISFAALHAYEASREGLALAAALLRPQGRLLLVDLLCESPLALLGAALLDDRPLRLAELPSLLADLAAAGLAPRCLWRSERIALVEALAPGLGLDAAALQAGLEQRLPQAMRPERLWCLPSLPLNGNGKVDRRRLAESMTRALG 7en1 A 3.47 BS03 AMP A 1 G814 D815 W816 L838 G839 G840 Y865 D927 F939 R942 K1325 G716 D717 W718 L740 G741 G742 Y767 D829 F841 R844 K1227 6.2.1.69 0003824,0005737,0009239,0009366,0016874,0017000,0031177,0043041,0047527 G3XCV2 35105906 1504 QDRDQPFELSSVQQAYWLGRGAGEVLGNVSCHAFLEFRTRDVDPQRLAAAAECVRQRHPMLRARFLDGRQQILPTPPLSCFDLQDWRTLQVDEAERDWQALRDWRAHECLAVERGQVFLLGLVRMPGGEDRLWLSLDLLAADVESLRLLLAELGVAYLAPERLAEPPALHFADYLAHRAAQRAEAAARARDYWLERLPRLPDAPALPLACAPESIRQPRTRRLAFQLSAGESRRLERLAAQHGVTLSSVFGCAFALVLARWSESAEFLLNVPLFDRHADDPRIGEVIADFTTLLLLECRMQAGVSFAEAVKSFQRNLHGAIDHAAFPALEVLREARRQGQPRSAPVVFASNLGEEGFVPAAFRDAFGDLHDMLSQTPQVWLDHQLYRVGDGILLAWDSVVGLFPEGLPETMFEAYVGLLQRLCDSAWGQPADLPLPWAQQARRALLNGQPACATARTLHRDFFLRAAEAPDADALLYRDQRVTRGELAERALRIAGGLREAGVRPGDAVEVSLPRGPQQVAAVFGVLAAGACYVPLDIDQPPARRRLIEEAAGVCLAITEEDDPQALPPRLDVQRLLRGPALAAPVPLAPQASAYVIYTSGSTGVPKGVEVSHAAAINTIDALLDLLRVNASDRLLAVSALDFDLSVFDLFGGLGAGASLVLPAQEQARDAAAWAEAIQRHAVSLWNSAPALLEMALSLPASQADYRSLRAVLLSGDWVALDLPGRLRPRCAEGCRLHVLGGATEAGIWSNLQSVDTVPPHWRSIPYGRPLPGQAYRVVDTHGRDVPDLVVGELWIGGASLARGYRNDPELSARRFVHDAQGRWYRTGDRGRYWGDGTLEFLGRVDQQVKVRGQRIELGEVEAALCAQAGVESACAAVLGGGVASLGAVLVPRLAPRAEGSMDLPAAQPFAGLAEAEAVLTREILGALLEAPLELDDGLRRRWLDWLADSAASALPSLDEALRRLGWQAAGLTAMGNALRGLLAGEQAPAALLLDPWLAPQAVAARLPDGREALARLLEALPTPAAGERLRVAVLDTRAGLWLDQGMASLLRPGLELTLFERSRVLLDAAATRLPERIVVQALDDGLLPAEHLGRYDRVISFAALHAYEASREGLALAAALLRPQGRLLLVDLLCESPLALLGAALLDDRPLRLAELPSLLADLAAAGLAPRCLWRSERIALVEALAPGLGLDAAALQAGLEQRLPQAMRPERLWCLPSLPLNGNGKVDRRRLAESMTRALGAEEPLEAHEQALAECWEAVLKRPVRRREASFFSLGGDSLLATRLLAGIRERFGVRLGMADFYRQPTLAGLARHLQVQT 7en1 B 3.47 BS03 AMP B 1 G814 D815 W816 L838 G839 G840 A841 T842 Y865 D927 F939 K948 R953 G808 D809 W810 L832 G833 G834 A835 T836 Y859 D921 F933 K942 R947 6.2.1.69 0003824,0005737,0009239,0009366,0016874,0017000,0031177,0043041,0047527 G3XCV2 35105906 1504 SRTALRDWLTEQLADLLGEPLADVRALADDDDLLGCGLDSIRLMYLQERLRARGSTLDFAQLAQRPCLGAWLDLLACADRLSAPATVALPTAQDRDQPFELSSVQQAYWLGRGAGEVLGNVSCHAFLEFRTRDVDPQRLAAAAECVRQRHPMLRARFLDGRQQILPTPPLSCFDLQDWRTLQVDEAERDWQALRDWRAHECLAVERGQVFLLGLVRMPGGEDRLWLSLDLLAADVESLRLLLAELGVAYLAPERLAEPPALHFADYLAHRAAQRAEAAARARDYWLERLPRLPDAPALPLACAPESIRQPRTRRLAFQLSAGESRRLERLAAQHGVTLSSVFGCAFALVLARWSESAEFLLNVPLFDRHADDPRIGEVIADFTTLLLLECRMQAGVSFAEAVKSFQRNLHGAIDHAAFPALEVLREARRQGQPRSAPVVFASNLGEEGFVPAAFRDAFGDLHDMLSQTPQVWLDHQLYRVGDGILLAWDSVVGLFPEGLPETMFEAYVGLLQRLCDSAWGQPADLPLPWAQQARRALLNGQPACATARTLHRDFFLRAAEAPDADALLYRDQRVTRGELAERALRIAGGLREAGVRPGDAVEVSLPRGPQQVAAVFGVLAAGACYVPLDIDQPPARRRLIEEAAGVCLAITEEDDPQALPPRLDVQRLLRGPALAAPVPLAPQASAYVIYTSGSTGVPKGVEVSHAAAINTIDALLDLLRVNASDRLLAVSALDFDLSVFDLFGGLGAGASLVLPAQEQARDAAAWAEAIQRHAVSLWNSAPALLEMALSLPASQADYRSLRAVLLSGDWVALDLPGRLRPRCAEGCRLHVLGGATEAGIWSNLQSVDTVPPHWRSIPYGRPLPGQAYRVVDTHGRDVPDLVVGELWIGGASLARGYRNDPELSARRFVHDAQGRWYRTGDRGRYWGDGTLEFLGRVDQQVKVRGQRIELGEVEAALCAQAGVESACAAVLGGGVASLGAVLVPRLAPRAEGSMDLPAAQPFAGLAEAEAVLTREILGALLEAPLELDDGLRRRWLDWLADSAASALPSLDEALRRLGWQAAGLTAMGNALRGLLAGEQAPAALLLDPWLAPQAVAARLPDGREALARLLEALPTPAAGERLRVAVLDTRAGLWLDQGMASLLRPGLELTLFERSRVLLDAAATRLPERIVVQALDDGLLPAEHLGRYDRVISFAALHAYEASREGLALAAALLRPQGRLLLVDLLCESPLALLGAALLDDRPLRLAELPSLLADLAAAGLAPRCLWRSERIALVEALAPGLGLDAAALQAGLEQRLPQAMRPERLWCLPSLPLNGNGKVDRRRLAESMTRALG 7en2 A 3.78 BS02 AMP A 1 G814 D815 L838 G839 G840 A841 T842 Y865 D927 F939 R942 K1325 G717 D718 L741 G742 G743 A744 T745 Y768 D830 F842 R845 K1228 6.2.1.69 0003824,0005737,0009239,0009366,0016874,0017000,0031177,0043041,0047527 G3XCV2 35105906 1502 AQDRDQPFELSSVQQAYWLGRGAGEVLGNVSCHAFLEFRTRDVDPQRLAAAAECVRQRHPMLRARFLDGRQQILPTPPLSCFDLQDWRTLQVDEAERDWQALRDWRAHECLAVERGQVFLLGLVRMPGGEDRLWLSLDLLAADVESLRLLLAELGVAYLAPERLAEPPALHFADYLAHRAAQRAEAAARARDYWLERLPRLPDAPALPLACAPESIRQPRTRRLAFQLSAGESRRLERLAAQHGVTLSSVFGCAFALVLARWSESAEFLLNVPLFDRHADDPRIGEVIADFTTLLLLECRMQAGVSFAEAVKSFQRNLHGAIDHAAFPALEVLREARRQGQPRSAPVVFASNLGEEGFVPAAFRDAFGDLHDMLSQTPQVWLDHQLYRVGDGILLAWDSVVGLFPEGLPETMFEAYVGLLQRLCDSAWGQPADLPLPWAQQARRALLNGQPACATARTLHRDFFLRAAEAPDADALLYRDQRVTRGELAERALRIAGGLREAGVRPGDAVEVSLPRGPQQVAAVFGVLAAGACYVPLDIDQPPARRRLIEEAAGVCLAITEEDDPQALPPRLDVQRLLRGPALAAPVPLAPQASAYVIYTSGSTGVPKGVEVSHAAAINTIDALLDLLRVNASDRLLAVSALDFDLSVFDLFGGLGAGASLVLPAQEQARDAAAWAEAIQRHAVSLWNSAPALLEMALSLPASQADYRSLRAVLLSGDWVALDLPGRLRPRCAEGCRLHVLGGATEAGIWSNLQSVDTVPPHWRSIPYGRPLPGQAYRVVDTHGRDVPDLVVGELWIGGASLARGYRNDPELSARRFVHDAQGRWYRTGDRGRYWGDGTLEFLGRVDQQVKVRGQRIELGEVEAALCAQAGVESACAAVLGGGVASLGAVLVPRLAPRAEGSMDLPAAQPFAGLAEAEAVLTREILGALLEAPLELDDGLRRRWLDWLADSAASALPSLDEALRRLGWQAAGLTAMGNALRGLLAGEQAPAALLLDPWLAPQAVAARLPDGREALARLLEALPTPAAGERLRVAVLDTRAGLWLDQGMASLLRPGLELTLFERSRVLLDAAATRLPERIVVQALDDGLLPAEHLGRYDRVISFAALHAYEASREGLALAAALLRPQGRLLLVDLLCESPLALLGAALLDDRPLRLAELPSLLADLAAAGLAPRCLWRSERIALVEALAPGLGLDAAALQAGLEQRLPQAMRPERLWCLPSLPLNGNGKVDRRRLAESMTRALGAEEPLEAHEQALAECWEAVLKRPVRRREASFFSLGGDSLLATRLLAGIRERFGVRLGMADFYRQPTLAGLARHLQVQT 7en2 B 3.78 BS02 AMP B 1 G814 D815 L838 G839 G840 A841 T842 Y865 D927 F939 G806 D807 L830 G831 G832 A833 T834 Y857 D919 F931 6.2.1.69 0003824,0005737,0009239,0009366,0016874,0017000,0031177,0043041,0047527 G3XCV2 35105906 1502 SRTALRDWLTEQLADLLGEPLADVRALADDDDLLGCGLDSIRLMYLQERLRARGSTLDFAQLAQRPCLGAWLDLLACADSAPATVALPTAQDRDQPFELSSVQQAYWLGRGAGEVLGNVSCHAFLEFRTRDVDPQRLAAAAECVRQRHPMLRARFLDGRQQILPTPPLSCFDLQDWRTLQVDEAERDWQALRDWRAHECLAVERGQVFLLGLVRMPGGEDRLWLSLDLLAADVESLRLLLAELGVAYLAPERLAEPPALHFADYLAHRAAQRAEAAARARDYWLERLPRLPDAPALPLACAPESIRQPRTRRLAFQLSAGESRRLERLAAQHGVTLSSVFGCAFALVLARWSESAEFLLNVPLFDRHADDPRIGEVIADFTTLLLLECRMQAGVSFAEAVKSFQRNLHGAIDHAAFPALEVLREARRQGQPRSAPVVFASNLGEEGFVPAAFRDAFGDLHDMLSQTPQVWLDHQLYRVGDGILLAWDSVVGLFPEGLPETMFEAYVGLLQRLCDSAWGQPADLPLPWAQQARRALLNGQPACATARTLHRDFFLRAAEAPDADALLYRDQRVTRGELAERALRIAGGLREAGVRPGDAVEVSLPRGPQQVAAVFGVLAAGACYVPLDIDQPPARRRLIEEAAGVCLAITEEDDPQALPPRLDVQRLLRGPALAAPVPLAPQASAYVIYTSGSTGVPKGVEVSHAAAINTIDALLDLLRVNASDRLLAVSALDFDLSVFDLFGGLGAGASLVLPAQEQARDAAAWAEAIQRHAVSLWNSAPALLEMALSLPASQADYRSLRAVLLSGDWVALDLPGRLRPRCAEGCRLHVLGGATEAGIWSNLQSVDTVPPHWRSIPYGRPLPGQAYRVVDTHGRDVPDLVVGELWIGGASLARGYRNDPELSARRFVHDAQGRWYRTGDRGRYWGDGTLEFLGRVDQQVKVRGQRIELGEVEAALCAQAGVESACAAVLGGGVASLGAVLVPRLAPRAEGSMDLPAAQPFAGLAEAEAVLTREILGALLEAPLELDDGLRRRWLDWLADSAASALPSLDEALRRLGWQAAGLTAMGNALRGLLAGEQAPAALLLDPWLAPQAVAARLPDGREALARLLEALPTPAAGERLRVAVLDTRAGLWLDQGMASLLRPGLELTLFERSRVLLDAAATRLPERIVVQALDDGLLPAEHLGRYDRVISFAALHAYEASREGLALAAALLRPQGRLLLVDLLCESPLALLGAALLDDRPLRLAELPSLLADLAAAGLAPRCLWRSERIALVEALAPGLGLDAAALQAGLEQRLPQAMRPERLWCLPSLPLNGNGKVDRRRLAESMTRALGAEEPLEAHEQALAECWEAVLKRPVRRREASFFSLGGDSLLATRLLAGIRERFGVRLGMADFYRQPTLAGLARHLQVQT 7esc A 2.201 BS01 AMP A 1 D128 I131 D184 A187 H273 I274 L275 D93 I96 D149 A152 H238 I239 L240 2.7.1.180 0005524,0005886,0016740,0017013,0046872 A0A0H3GJF7 35281791 401 KLMDQPYSKTDFLMGTVVTLKIYDKGKEDVLDKGFDRIKDLAAKITTSDSEKTSEVDKINEQAGKKPVKVSEDVYYLIQEGLKYSENSGGSFDITIGPLTSLWHIGFSDARKPSQAEIDAVLPLINYKDVKMNDKDQTVYLEKEGMELDLGAIAKGFITDETLKVFKENKVTTSIIDLGGNIYVQGNNPNGNKWNVGIQDPFSPRGSVIGKLPESNMSIVTSGIYERYLEVDGKTYHHILDPKTGYPFDNDIAGVSIVSKKSIDGDGLSTATFSKGIKGGMDYIEQFEGVDAIFISKEKKVYETSGLKGQFELTDKDFQMDT 7fj8 A 2.1 BS01 AMP A 1 G209 N210 D282 Y283 R284 G330 I331 N334 G208 N209 D281 Y282 R283 G329 I330 N333 2.7.2.15 0005524,0005737,0006082,0006083,0008776,0008980,0016301,0016310,0016774,0019543,0051144 A6TDE9 501 TYKIMAINAGSSSLKFQLLNMPQGALLCQGLIERIGLPEARFTLKTSAQKWQETLPIADHHEAVTLLLEALTGRGILSSLQEIDGVGHRVAHGGERFKDAALVCDDTLREIERLAELAPLHNPVNALGIRLFRQLLPAVPAVAVFDTAFHQTLAPEAWLYPLPWRYYAELGIRRYGFHGTSHHYVSSALAEKLGVPLSALRVVSCHLGNGCSVCAIKGGQSVNTSMGFTPQSGVMMGTRSGDIDPSILPWLVEKEGKSAQQLSQLLNNESGLLGVSGVSSDYRDVEQAADAGNERAALALSLFAERIRATIGSYIMQMGGLDALIFTGGIGENSARARAAICRNLHFLGLALDDEKNQRSATFIQADNALVKVAVINTNEELMIARDVMRLALPQ 7gpb A 2.9 BS02 AMP A 1 Q71 Q72 Y75 R309 R310 Q62 Q63 Y66 R295 R296 H377 K568 R569 K574 T676 K680 H363 K554 R555 K560 T662 K666 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 -logKd/Ki=5.52, Kd=3uM P00489 1900534 920 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 7gpb A 2.9 BS03 AMP B 1 D42 N44 V45 D33 N35 V36 H377 K568 R569 K574 T676 K680 H363 K554 R555 K560 T662 K666 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 -logKd/Ki=5.52, Kd=3uM P00489 1900534 920 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 7gpb B 2.9 BS02 AMP B 1 Q71 Y75 R309 R310 Q62 Y66 R295 R296 H377 K568 R569 K574 T676 K680 H363 K554 R555 K560 T662 K666 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 -logKd/Ki=5.52, Kd=3uM P00489 1900534 920 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 7gpb C 2.9 BS02 AMP C 1 Q71 Y75 R309 R310 Q62 Y66 R295 R296 H377 K568 R569 K574 T676 K680 H363 K554 R555 K560 T662 K666 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 1900534 920 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 7gpb C 2.9 BS03 AMP D 1 N44 V45 N35 V36 H377 K568 R569 K574 T676 K680 H363 K554 R555 K560 T662 K666 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 1900534 920 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 7gpb D 2.9 BS01 AMP C 1 D42 N44 V45 D33 N35 V36 H377 K568 R569 K574 T676 K680 H363 K554 R555 K560 T662 K666 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 1900534 920 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 7gpb D 2.9 BS03 AMP D 1 Q71 Q72 Y75 R309 R310 Q62 Q63 Y66 R295 R296 H377 K568 R569 K574 T676 K680 H363 K554 R555 K560 T662 K666 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 P00489 1900534 920 RKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAP 7jhg G 3.47 BS03 AMP G 1 H151 T200 I204 A205 V225 A227 H298 I312 S314 S316 H127 T176 I180 A181 V201 A203 H274 I288 S290 S292 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 34437114 403 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 7jhh G 3.92 BS03 AMP G 1 H151 T200 I204 A205 V225 A227 H298 I312 S314 S316 H127 T176 I180 A181 V201 A203 H274 I288 S290 S292 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 34437114 403 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 7jij G 5.5 BS02 AMP G 1 H151 T200 V225 S314 S316 D317 H127 T176 V201 S290 S292 D293 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 34437114 402 NNSVYTFFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 7k05 A 1.85 BS01 AMP A 1 D150 E152 A153 C155 K157 Q159 F199 L203 H307 D15 E17 A18 C20 K22 Q24 F64 L68 H172 3.1.-.- 0000175,0003676 O43414 501 MSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSK 7k05 B 1.85 BS01 AMP B 1 E152 A153 C155 Q159 F199 L203 H307 E17 A18 C20 Q24 F64 L68 H172 3.1.-.- 0000175,0003676 O43414 501 MSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSK 7k07 A 2.15 BS01 AMP A 1 D150 E152 A153 C155 K157 F199 L203 D15 E17 A18 C20 K22 F64 L68 3.1.-.- 0000175,0003676 O43414 501 MSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSK 7k07 B 2.15 BS01 AMP B 1 E152 A153 C155 F199 L203 E17 A18 C20 F64 L68 3.1.-.- 0000175,0003676 O43414 501 MSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSK 7k5j A 3.42 BS01 AMP A 1 G443 A444 D470 N471 K494 K519 V520 L543 D544 A548 G432 A433 D459 N460 K483 K508 V509 L532 D533 A537 R21 R481 D544 C600 T601 R603 R10 R470 D533 C583 T584 R586 6.2.1.45 0004839,0005515,0005524,0005634,0005737,0006511,0006974,0008641,0016567,0016874,0036211,0043412 P22515 33888705 1101 GEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKKPNVDEYKSVIDHMIIPEFTPNIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL 7k5j C 3.42 BS01 AMP C 1 A444 D470 D472 K494 K519 V520 A542 L543 D544 A433 D459 D461 K483 K508 V509 A531 L532 D533 R21 R481 D544 C600 T601 R603 R10 R470 D533 C581 T582 R584 6.2.1.45 0004839,0005515,0005524,0005634,0005737,0006511,0006974,0008641,0016567,0016874,0036211,0043412 P22515 33888705 1101 GEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLDVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKKPNVDEYKSVIDHMIIPEFTPNEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL 7k5j D 3.42 BS01 AMP D 1 G443 A444 D470 N471 D472 K494 K519 V520 L543 D544 N545 G432 A433 D459 N460 D461 K483 K508 V509 L532 D533 N534 R21 R481 D544 C600 T601 R603 R10 R470 D533 C580 T581 R583 6.2.1.45 0004839,0005515,0005524,0005634,0005737,0006511,0006974,0008641,0016567,0016874,0036211,0043412 P22515 33888705 1101 GEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKDVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKKPNVDEYKSVIDHMIIPEFTPNEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL 7k5j G 3.42 BS01 AMP G 1 G443 A444 D470 D472 K494 V520 L543 D544 G432 A433 D459 D461 K483 V509 L532 D533 R21 R481 D544 C600 T601 R603 R10 R470 D533 C581 T582 R584 6.2.1.45 0004839,0005515,0005524,0005634,0005737,0006511,0006974,0008641,0016567,0016874,0036211,0043412 P22515 33888705 1101 GEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKDVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKKPNVDEYKSVIDHMIIPEFTPNEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL 7k5j I 3.42 BS01 AMP I 1 G443 A444 D470 K494 K519 V520 L543 D544 N545 G432 A433 D459 K483 K508 V509 L532 D533 N534 R21 R481 D544 C600 T601 R603 R10 R470 D533 C581 T582 R584 6.2.1.45 0004839,0005515,0005524,0005634,0005737,0006511,0006974,0008641,0016567,0016874,0036211,0043412 P22515 33888705 1101 GEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKDVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL 7k5j K 3.42 BS01 AMP K 1 D470 K494 K519 V520 L543 D544 D459 K483 K508 V509 L532 D533 R21 R481 D544 C600 T601 R603 R10 R470 D533 C581 T582 R584 6.2.1.45 0004839,0005515,0005524,0005634,0005737,0006511,0006974,0008641,0016567,0016874,0036211,0043412 P22515 33888705 1101 GEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKDVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL 7k5j S 3.42 BS01 AMP S 1 G443 A444 D470 Q482 K494 K519 L543 G432 A433 D459 Q471 K483 K508 L532 R21 R481 D544 C600 T601 R603 R10 R470 D533 C581 T582 R584 6.2.1.45 0004839,0005515,0005524,0005634,0005737,0006511,0006974,0008641,0016567,0016874,0036211,0043412 P22515 33888705 1101 GEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLDVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKKPNVDEYKSVIDHMIIPEFTPNIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL 7kr3 A 2.778 BS04 AMP C 1 K568 Y569 R573 E621 F660 M723 K725 K744 K299 Y300 R304 E352 F391 M454 K456 K475 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 33473124 101 DPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 7kr4 A 2.2 BS04 AMP C 1 K568 Y569 R573 E621 F660 M723 K725 K744 K306 Y307 R311 E359 F398 M461 K463 K482 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 33473124 101 SNDMDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 7kwm A 2.3 BS01 AMP A 1 G181 R184 Y203 D204 P205 Y206 C237 N243 G156 R159 Y178 D179 P180 Y181 C212 N218 1.1.1.- 0003714,0016616,0051287 Q13363 33524397 401 HMPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGFGRTGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHL 7l29 A 2.08 BS01 AMP A 1 H752 H836 D837 L910 D950 Q1001 F1004 H84 H150 D151 L224 D264 Q315 F318 3.1.4.17 0004114,0007165,0008081 Q14432 34272366 1101 KPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTVIGGSYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVRKIYCQITQHLLQNHKMWKKVIEEE 7l29 B 2.08 BS01 AMP B 1 H752 H756 D837 L910 D950 Q1001 F1004 H84 H88 D150 L223 D263 Q314 F317 3.1.4.17 0004114,0007165,0008081 Q14432 34272366 1101 KPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTVIGSYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVEGRKIYCQITQHLLQNHKMWKKVIEEEQR 7l29 C 2.08 BS01 AMP C 1 H752 D837 D950 Q1001 F1004 H83 D149 D262 Q313 F316 3.1.4.17 0004114,0007165,0008081 Q14432 34272366 1101 PILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTVIGSYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVEGRKIYCQITQHLLQNHKMWKKVIEEEQR 7l29 D 2.08 BS01 AMP D 1 H752 H756 D837 L910 D950 Q1001 F1004 H84 H88 D154 L227 D267 Q318 F321 3.1.4.17 0004114,0007165,0008081 Q14432 34272366 1101 KPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTVIGGSGGSYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVRKIYCQITQHLLQNHKMWKKVIEEEQ 7l34 A 1.901 BS04 AMP C 1 K568 Y569 R573 R589 E621 F660 M723 K725 W742 K744 K305 Y306 R310 R326 E358 F397 M460 K462 W479 K481 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 33444456 101 SNDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTLKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQ 7l35 A 2.0 BS04 AMP C 1 K568 Y569 R573 E621 F660 M723 K725 K744 K746 K301 Y302 R306 E354 F393 M456 K458 K477 K479 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 33444456 101 SNDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKWAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 7l8n A 1.94 BS01 AMP A 1 D181 G182 Y197 L198 T212 D68 G69 Y84 L85 T99 2.7.7.85 Q8DTC4 301 QQLSDDEKLVAAFVKAVAYMSPRKIGALVSIEETQTLREYIATGIPLDADISGELLINIFIPNTPLHDGAVIVEGNKIAVSCAYLPLSESSHISKEFGTRHRAAIGLSEASDAFTFVVSEETGAISVAYKGDFIHDLSLEAFEVLLREHFI 7lhu A 3.09 BS02 AMP A 1 A64 S65 N66 L88 T161 G162 A48 S49 N50 L72 T145 G146 V214 Y218 V198 Y202 1.8.4.10 0003824,0004604,0005737,0005829,0005886,0016491,0019344,0019379,0043866,0046872,0051536,0051539 P9WIK3 34095667 303 TTRLTEPQLRELAARGAAELDGATATDMLRWTDETFGDIWTTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIGTRDAIESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPLGKTLRGYSAWVTGLRRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDVQEYIADNDVLVNPLVREGYPSIGCAPCTAKP 7lhu B 3.09 BS02 AMP B 1 A64 S65 N66 L88 T161 G162 A42 S43 N44 L66 T139 G140 V214 Y218 V192 Y196 1.8.4.10 0003824,0004604,0005737,0005829,0005886,0016491,0019344,0019379,0043866,0046872,0051536,0051539 P9WIK3 34095667 303 LTEPQLRELAARGAAELDGATATDMLRWTDETFGDTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIGTRDAIESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPLGKTLRGYSAWVTGLRRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDVQEYIADNDVLVNPLVREGYPSIGCAPCTAKPA 7lpy A 1.85 BS01 AMP A 1 D150 E152 A153 C155 K157 Q159 F199 L203 W248 D15 E17 A18 C20 K22 Q24 F64 L68 W113 3.1.-.- 0000175,0003676 O43414 501 MSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSK 7lpy B 1.85 BS01 AMP B 1 D150 E152 A153 C155 Q159 F199 L203 W248 D15 E17 A18 C20 Q24 F64 L68 W113 3.1.-.- 0000175,0003676 O43414 501 MSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSK 7lpz A 1.55 BS01 AMP A 1 E152 A153 C155 K157 Q159 F199 L203 W248 H307 E18 A19 C21 K23 Q25 F65 L69 W114 H173 3.1.-.- 0000175,0003676 O43414 501 SMSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSK 7lpz B 1.55 BS01 AMP B 1 F151 E152 A153 C155 Q159 F199 L203 W248 H307 F17 E18 A19 C21 Q25 F65 L69 W114 H173 3.1.-.- 0000175,0003676 O43414 501 SMSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSK 7lq0 A 1.6 BS01 AMP A 1 E152 A153 C155 K157 Q159 F199 L203 H307 E17 A18 C20 K22 Q24 F64 L68 H172 3.1.-.- 0000175,0003676 O43414 501 MSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSK 7lq0 B 1.6 BS01 AMP B 1 F151 E152 A153 C155 Q159 F199 L203 W248 H307 F16 E17 A18 C20 Q24 F64 L68 W113 H172 3.1.-.- 0000175,0003676 O43414 501 MSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTFHMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLLDPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMGCWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTSK 7m74 G 3.93 BS03 AMP G 1 H151 T200 V225 H298 I312 S314 S316 H127 T176 V201 H274 I288 S290 S292 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 34437114 403 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 7mir A 2.5 BS01 AMP A 1 H492 R500 D502 Y506 Q507 V510 Q517 Q519 G521 H394 R402 D404 Y408 Q409 V412 Q419 Q421 G423 6.-.-.- Q5ZTK6 34407442 901 VKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWREA 7mis A 2.8 BS04 AMP C 1 H492 R500 Y506 Q507 V510 Q517 Q519 G521 H395 R403 Y409 Q410 V413 Q420 Q422 G424 6.-.-.- Q5ZTK6 34407442 2000 HVKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWR 7myj E 2.95 BS01 AMP E 1 H151 T200 I204 A205 V225 S226 H298 I312 S314 S316 D317 H128 T177 I181 A182 V202 S203 H275 I289 S291 S293 D294 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 35552369 401 SNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTG 7myj E 2.95 BS02 AMP E 2 R70 K170 I240 S242 D245 R269 V276 L277 V297 H298 R299 R47 K147 I217 S219 D222 R246 V253 L254 V274 H275 R276 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 35552369 402 SNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTG 7myj F 2.95 BS01 AMP F 1 H151 T200 I204 A205 V225 S226 H298 S314 S316 D317 H128 T177 I181 A182 V202 S203 H275 S291 S293 D294 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 35552369 401 SNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTG 7myj F 2.95 BS02 AMP F 2 K170 I240 S242 F244 D245 R269 V276 L277 V297 H298 R299 K147 I217 S219 F221 D222 R246 V253 L254 V274 H275 R276 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 35552369 402 SNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTG 7n1r A 2.03 BS02 AMP A 1 T38 G227 E293 K296 R297 S300 G363 G364 R367 D391 T15 G204 E270 K273 R274 S277 G340 G341 R344 D368 3.6.4.10 0005509,0005515,0005524,0005634,0005737,0005739,0005783,0005788,0005789,0005793,0005829,0005886,0005925,0006983,0008180,0009986,0016020,0016787,0016887,0019899,0019904,0021589,0021680,0021762,0030335,0030496,0030512,0030968,0031072,0031204,0031333,0031398,0031625,0032991,0034663,0034975,0034976,0035437,0036503,0042026,0042149,0042470,0043022,0043066,0043231,0044183,0045296,0045944,0051082,0051085,0051087,0051603,0051787,0060904,0070062,0071353,0140662,1903891,1903894,1903895,1903897 P11021 34941000 715 SEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSVGGTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISK 7n1r B 2.03 BS02 AMP B 1 T38 G227 E293 K296 R297 S300 G363 G364 S365 R367 D391 T15 G204 E270 K273 R274 S277 G340 G341 S342 R344 D368 3.6.4.10 0005509,0005515,0005524,0005634,0005737,0005739,0005783,0005788,0005789,0005793,0005829,0005886,0005925,0006983,0008180,0009986,0016020,0016787,0016887,0019899,0019904,0021589,0021680,0021762,0030335,0030496,0030512,0030968,0031072,0031204,0031333,0031398,0031625,0032991,0034663,0034975,0034976,0035437,0036503,0042026,0042149,0042470,0043022,0043066,0043231,0044183,0045296,0045944,0051082,0051085,0051087,0051603,0051787,0060904,0070062,0071353,0140662,1903891,1903894,1903895,1903897 P11021 34941000 715 SEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSVGGTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISK 7n8t A 1.69 BS01 AMP A 1 I32 A53 M111 N114 S155 L168 I23 A44 M102 N105 S146 L159 2.7.11.24 0004672,0004707,0005524,0006468 P45984 36826833 401 FYSVEVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGYAANVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMAALQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWE 7n8w A 2.35 BS01 AMP A 1 E43 S44 C46 L96 E14 S15 C17 L67 3.1.-.- 0000175,0003676 A8K979 301 SKQLFDYLIVIDFESTCWNDGKHHHSQEIIEFPAVLLNTSTGQIDSEFQAYVQPQEHPILSEFCMELTGIKQAQVDEGVPLKICLSQFCKWIHKIQQQKNIIFATGISEPSASEVKLCAFVTWSDWDLGVCLEYECKRKQLLKPVFLNSWIDLRATYKLFYRRKPKGLSGALQEVGIEFSGREASGLDASRNTALLAWKMIRDGCVMKITRSLN 7n8w B 2.35 BS01 AMP A 1 K51 H52 H53 H54 K22 H23 H24 H25 3.1.-.- 0000175,0003676 A8K979 301 SKQLFDYLIVIDFESTCWNDGKHHHSQEIIEFPAVLLNTSTGQIDSEFQAYVQPQEHPILSEFCMELTGIKQAQVDEGVPLKICLSQFCKWIHKIQQQKNIIFATGISEPSASEVKLCAFVTWSDWDLGVCLEYECKRKQLLKPVFLNSWIDLRATYKLFYRRKPKGLSGALQEVGIEFSGREASGLDASRNTALLAWKMIRDGCVMKITRSL 7obn A 2.45 BS03 AMP A 1 S28 P29 K30 I31 R35 E73 F105 M174 K196 S27 P28 K29 I30 R34 E72 F100 M160 K182 0003909,0003910,0005524,0006281,0006310 34548548 401 TIPTGFKPMLAATLTKPELIKFPVWASPKIDGIRCVFFGGVAYSRSLKPIPNPVVQEFAAAYASLLEGLDGELTVGSPTDANCMQNSMAVMSKDFTFHVFDWFPLRDEMGYDRRSEIVERRIADFYARDIKAVPQHLCVCAEDLDTLEARFLADGYEGMMIRAHSGTYKCGRSTEREGGLVKVKRFVDGEAVIVGFEEEMRNENEATRNATGRTERSTAQAGLVGKETLGALVVRRFEEPYGPVGPEFNIGTGFTAAQRRDYWQGRDGLIGRVVKFKHFDHGTVDAPRHPVFIGFRHPE 7p7f A 1.96 BS01 AMP A 1 I23 A36 K38 M82 L85 D149 I21 A34 K36 M80 L83 D147 2.7.11.1,2.7.11.26 0004672,0005524,0006468 P48730 35353987 305 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 7p7f B 1.96 BS01 AMP B 1 G18 I23 A36 K38 M82 L85 L135 I148 D149 G16 I21 A34 K36 M80 L83 L133 I146 D147 2.7.11.1,2.7.11.26 0004672,0005524,0006468 P48730 35353987 310 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 7p7g A 1.7 BS01 AMP A 1 I23 A36 K38 L85 I148 D149 I16 A29 K31 L78 I141 D142 2.7.11.1,2.7.11.26 0004672,0005524,0006468 P48730 35353987 303 RYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 7p7g B 1.7 BS01 AMP B 1 I15 G18 I23 A36 K38 M82 L85 D132 L135 I148 D149 I9 G12 I17 A30 K32 M76 L79 D126 L129 I142 D143 2.7.11.1,2.7.11.26 0004672,0005524,0006468 P48730 35353987 307 NRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFDYVFDWNML 7p7h A 2.4 BS01 AMP A 1 A36 M82 L85 D132 L135 I148 D149 A34 M80 L83 D130 L133 I146 D147 2.7.11.1,2.7.11.26 0004672,0005524,0006468 P48730 35353987 301 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 7p7h B 2.4 BS01 AMP B 1 S17 I23 A36 K38 M82 L85 I148 D149 S15 I21 A34 K36 M80 L83 I146 D147 2.7.11.1,2.7.11.26 0004672,0005524,0006468 P48730 35353987 301 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 7p9n A 1.55 BS04 AMP A 1 R354 N390 G392 R395 F417 G447 F500 D506 R329 N365 G367 R370 F392 G422 F475 D481 3.1.3.35,3.1.3.5,3.1.3.89,3.1.3.91,3.1.3.99 0000166,0002953,0005515,0005654,0005829,0005886,0006196,0006259,0007159,0008252,0008253,0008270,0009166,0009897,0009986,0010035,0016020,0016787,0016788,0033198,0042802,0046032,0046034,0046086,0046872,0050340,0050483,0050484,0050728,0055074,0070062,0098552,0106411,0110148,0140928 P21589 34403084 605 PWELTILHTNDVHSRLEQTSEDSSKCVDASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANISASGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLDSSIPEDPSIKADINKWRIKLDDYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHADEMFWNHVSMCILNGGGIRSPIDERNDGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTSCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFS 7qep L9 2.7 BS02 AMP L9 1 K22 P41 L42 T43 L55 W56 K22 P41 L42 T43 L55 W56 ? 0002181,0003735,0005840,0006412,0019843,0022625,1990904 Q8SSF7 201 MRILVTRIVKVPEDCTATQEGKIFTFQGPKGSIVEDCTRHPLTFDIHEGNIRIRLWNGKRKAMALAITVESLLRNAIKAVTVGFAYTMKAVYNHFSINMEIKEDGKILLVKNFLGEKNVKRFRMRGAARVRLDERKDTIVIEGPSLSDVSQSAGTITNECKAKNRDSRVFLDGIFVTERGIM 7qep N0 2.7 BS03 AMP L9 1 F169 K171 F160 K162 ? 0003735,0005840,0006412,0022625,1990904 Q8SRD7 201 AFSKVNMTIPMTKEYRIHGSAMPTEDNPRPQVFVGTIFTKNHVFAKAKFFKILEKKYKIKATKGLIIDCKEIPEPSFKEVQNYGIRFVYRSRSGVHNAYKECRAISKCWAIDHVLRELAGRQKLKRSAVDIISVDVVPVESLKRAKTIEFADENVEFPIFTKIVNTKSLLIPSEYNPS 7qnz A 4.58 BS04 AMP I 1 K568 R573 E621 F660 M723 K725 K744 K307 R312 E360 F399 M462 K464 K483 6.5.1.1 0003677,0003909,0003910,0005515,0005524,0005634,0005654,0005739,0006260,0006266,0006273,0006281,0006284,0006287,0006298,0006310,0009653,0016874,0033151,0043231,0046872,0051301,0071897,1903461 P18858 36539424 100 DPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 7qo1 A 4.4 BS04 AMP I 1 K568 Y569 R573 E621 F660 K744 K307 Y308 R312 E360 F399 K483 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 36539424 100 DPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 7qps A 2.79 BS01 AMP B 1 R236 K238 K329 R224 K226 K317 2.7.6.5 0015969 V5V8V7 401 PGEEVSQAKQQLKLIIDPYLSVSEVEKVLAACDFGDLAHTGITRKYILHPIAVSCILANMRLDPETLMAALLHDVIEDTQYTKDDIIERFGQTVAELVDGVTKLSNKAASFRKILQATLQDPRVIIIKLADRYHNMTTLGALRPDKRARIAQETFDIFVPMARLVGMNEMADNLENLCYQNLDLDMFDNVQNALLQTKPERCKYQSIWEQNLAELLHNYHIQGRIKKKNNNIELLRHFVKNEMDLQELTHSHAFEIVLQSIADCDRLVAALKENFQVIQYQDHIRRPLPGGNQSLMIKLKGEKTTLSLTIQTELMRKAARFG 7qps B 2.79 BS01 AMP B 1 R236 R328 R207 R299 2.7.6.5 0015969 V5V8V7 401 PGEEVSQAKQQLKLIIDPYLSVSEVEKVLAACDFGDLAHILHPIAVSCILANMRLDPETLMAALLHTKDDIIERFGQTVAELVDGVTKLSAASFRKILQATLQDPRVIIIKLADRYHNMTTLGALRPDKRARIAQETFDIFVPMARLVGMNEMADNLENLCYQNLDLDMFDNVQNALLQTKPERCKYQSIWEQNLAELLHNYHIQGRIKKKNNNIELLRHFVKNEMDLQELTHSHAFEIVLQSIADCDRLVAALKENFQVIQYQDHIRRPLPGGNQSLMIKLKGEKTTLSLTIQTELMRKAAR 7r27 A 2.01 BS02 AMP A 1 G271 E272 E273 N293 T294 Y295 G296 P297 D384 Y396 G264 E265 E266 N286 T287 Y288 G289 P290 D377 Y389 0005524,0047473,0070395 35907949 702 KNIITTIDDYARTQPNNVVYDVQGVTHTYAELKAYSDALAAHLDTLDLPAKDPIIVFGGQTFEMIATFLGVVKSGRAYIPIDTHSPNERLTMINEIAKPAAVIAVADLPTGVGTTPVITPDQLAAIFATPVDYQADHVVSGDDNYYIIFTMPKGVQISHDNLVSYVDWMLSDDFGLPDQPNSLSQPPYSFDLSVMDVYPTLALGGTLYALPKAVTDDFKQLFAALPTLPINVWVSTPSFMDICLLEPKFNAENLPTLTHFLFCGEELTHKTAATLKKRFPDARIFNTYGPTETCVAVTQIEITDAALAQYDRLPIGYAKADTRILVVDENGEAVPNGTEGELIIAGPSVSKGYLNNPEKTAKAFFELDGQPAYHSGDIGTMDADGLFRYRGRVD 7r27 B 2.01 BS02 AMP B 1 G271 E272 E273 N293 T294 Y295 G296 T298 I322 D384 Y396 G269 E270 E271 N291 T292 Y293 G294 T296 I320 D382 Y394 0005524,0047473,0070395 35907949 702 KNIITTIDDYARTQPNNVVYDVQGVTHTYAELKAYSDALAAHLDTLDLPAKDPIIVFGGQTFEMIATFLGVVKSGRAYIPIDTHSPNERLTMINEIAKPAAVIAVADLPTGVGTTPVITPDQLAAIFATPVDYQADHVVSGDDNYYIIFTSGTTGMPKGVQISHDNLVSYVDWMLSDDFGLPDQPNSLSQPPYSFDLSVMDVYPTLALGGTLYALPKAVTDDFKQLFAALPTLPINVWVSTPSFMDICLLEPKFNAENLPTLTHFLFCGEELTHKTAATLKKRFPDARIFNTYGPTETCVAVTQIEITDAALAQYDRLPIGYAKADTRILVVDENGEAVPNGTEGELIIAGPSVSKGYLNNPEKTAKAFFELDGQPAYHSGDIGTMDADGLFRYRGRV 7r7e A 1.99 BS01 AMP A 1 D214 A292 E293 P294 Y321 M323 A324 S370 D435 R449 D213 A291 E292 P293 Y320 M322 A323 S367 D432 R446 6.2.1.20 0008610 B1XKC6 601 VGQFANFVDLLQYRAKLQARKTVFSFLADGEAESAALTYGELDQKAQAIAAFLQANQAQGQRALLLYPPGLEFIGAFLGCLYAGVVAVPAYPPRPNKSFDRLHSIIQDAQAKFALTTTELKDKIADRLEALEGTDFHCLATDQVELISGKNWQKPNISGTDLAFLQYTSGSTGDPKGVMVSHHNLIHNSGLINQGFQDTEASMGVSWLPPYHDMGLIGGILQPIYVGATQILMPPVAFLQRPFRWLKAINDYRVSTSGAPNFAYDLCASQITPEQIRELDLSCWRLAFSGAEPIRAVTLENFAKTFATAGFQKSAFYPCYGMAETTLIVSGGNGRAQLPQEIIVSKQGIEANQVRPAQETTVTLVGSGEVIGDQIVKIVDPQALTECTVGEIGEVWVKGESVAQGYWQKPDLTQQQFQGNVGAETGFLRTGDLGFLQGGELYITGRLKDLLIIRGRNHYPQDIELTVEVAHPALRQGAGAAVSVDVNGEEQLVIVQEVERKYARKLNVAAVAQAIRGAIAAEHQLQPQAICFIKPGSIPKTSSGKIRRHACKAGFLDGSLAVVGEWQ 7r7e B 1.99 BS01 AMP B 1 D214 A292 E293 P294 Y321 G322 M323 A324 S370 D435 I446 D213 A291 E292 P293 Y320 G321 M322 A323 S367 D432 I443 6.2.1.20 0008610 B1XKC6 601 VGQFANFVDLLQYRAKLQARKTVFSFLADGEAESAALTYGELDQKAQAIAAFLQANQAQGQRALLLYPPGLEFIGAFLGCLYAGVVAVPAYPPRPNKSFDRLHSIIQDAQAKFALTTTELKDKIADRLEALEGTDFHCLATDQVELISGKNWQKPNISGTDLAFLQYTSGSTGDPKGVMVSHHNLIHNSGLINQGFQDTEASMGVSWLPPYHDMGLIGGILQPIYVGATQILMPPVAFLQRPFRWLKAINDYRVSTSGAPNFAYDLCASQITPEQIRELDLSCWRLAFSGAEPIRAVTLENFAKTFATAGFQKSAFYPCYGMAETTLIVSGGNGRAQLPQEIIVSKQGIEANQVRPAQETTVTLVGSGEVIGDQIVKIVDPQALTECTVGEIGEVWVKGESVAQGYWQKPDLTQQQFQGNVGAETGFLRTGDLGFLQGGELYITGRLKDLLIIRGRNHYPQDIELTVEVAHPALRQGAGAAVSVDVNGEEQLVIVQEVERKYARKLNVAAVAQAIRGAIAAEHQLQPQAICFIKPGSIPKTSSGKIRRHACKAGFLDGSLAVVGEWQ 7rpo E 4.16 BS05 AMP E 1 Y259 K260 R265 F350 E409 M412 K433 Y261 K262 R267 F352 E411 M414 K435 6.5.1.1 0003677,0003909,0003910,0005524,0006260,0006266,0006273,0006281,0006310,0016874,0046872,0051301,0071897 Q980T8 34838188 701 SHMEFKVIAEYFDKLEKISSRLQLTALLADLLSKSDKTIIDKVVYIIQGKLWPDFLGYPELGIGEKFLIKAISIATNTDENSVENLYKTIGDLGEVARRLKSKQQSTGILGFLGTTSKESLTVDEVYSTLSKVALTTGEGSRDLKIRLLAGLLKKADPLEAKFLVRFVEGRLRVGIGDATVLDAMAIAFGGGQSASEIIERAYNLRADLGNIAKIIVEKGIEALKTLKPQVGIPIRPMLAERLSNPEEILKKMGGNAIVDYKYDGERAQIHKKEDKIFIFSRRLENITSQYPDVVDYVSKYIEGKEFIIEGEIVAIDPESGEMRPFQELMHRKRKSDIYEAIKEYPVNVFLFDLMYYEDVDYTTKPLEARRKLLESIVKPNDYVKIAHHIQANNVEDLKSFFYRAISEGGEGVMVKAIGKDAIYQAGARGWLWIKLKRD 7rpw E 4.38 BS05 AMP Y 1 Y259 K260 Y261 R265 R280 E310 M412 K414 W431 Y261 K262 Y263 R267 R282 E312 M414 K416 W433 6.5.1.1 0003677,0003909,0003910,0005524,0006260,0006266,0006273,0006281,0006310,0016874,0046872,0051301,0071897 Q980T8 34838188 101 SHMEFKVIAEYFDKLEKISSRLQLTALLADLLSKSDKTIIDKVVYIIQGKLWPDFLGYPELGIGEKFLIKAISIATNTDENSVENLYKTIGDLGEVARRLKSKQQSTGILGFLGTTSKESLTVDEVYSTLSKVALTTGEGSRDLKIRLLAGLLKKADPLEAKFLVRFVEGRLRVGIGDATVLDAMAIAFGGGQSASEIIERAYNLRADLGNIAKIIVEKGIEALKTLKPQVGIPIRPMLAERLSNPEEILKKMGGNAIVDYKYDGERAQIHKKEDKIFIFSRRLENITSQYPDVVDYVSKYIEGKEFIIEGEIVAIDPESGEMRPFQELMHRKRKSDIYEAIKEYPVNVFLFDLMYYEDVDYTTKPLEARRKLLESIVKPNDYVKIAHHIQANNVEDLKSFFYRAISEGGEGVMVKAIGKDAIYQAGARGWLWIKLKRD 7snb A 1.11 BS01 AMP A 1 N32 Y34 T41 N44 N82 S83 I86 V128 T131 I132 L133 D185 G187 N47 Y49 T56 N59 N97 S98 I101 V143 T146 I147 L148 D200 G202 ? 0004371,0006071 Q2FZ58 303 HHHHHSSGLVPRGSHMISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTNMNLTMTSGREEVENNLSKNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIESESEINSKLLAESFQAGVETAYKAVMKPVEGTILTVAKDAAQAAIEKANNTEDCIELMEYIIVKANESLENTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKALKGEKV 7sol A 2.25001 BS02 AMP B 1 G469 A470 D497 D499 R508 K521 K544 V545 L568 D569 G430 A431 D458 D460 R469 K482 K505 V506 L529 D530 6.2.1.45 0004792,0004839,0005515,0005524,0005737,0005829,0006511,0007612,0007626,0008641,0016567,0016779,0016874,0019780,0021764,0021766,0032446,0036211,0060996 A0AVT1 35986001 1101 DDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQAWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCVVLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEEPKEIFISNITQANPGIVTCLENHPHKLETGQFLTFREINGMTGLNGSIQQITVISPFSFSIGDTTELEPYLHGGIAVQVKTPKTVFFESLERQLKHPKCLIVDFSNPEAPLEIHTAMLALDQFQEKYSRKPNVGCQQDSEELLKLATSISETLEEKPDVNADIVHWLSWTAQGFLSPLAAAVGGVASQEVLKAVTGKFSPLCQWLYLEAADIVESLGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCPTTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEEEIPFATLKSFPAAIEHTIQWARDKFESSFSHKPSLFNKFWQTYSSAEEVLQKIQSGHSLEGCFQVIKLLSRRPRNWSQCVELARLKFEKYFNHKALQLLHCFPLDIRLKDGSLFWQSPKRPPSPIKFDLNEPLHLSFLQNAAKLYATVYCIPFAEEDLSADALLNILSEVKIQEFKPSNKVVQTDETARKPDHVPISSEDERNAIFQLEKAILSNEATKSDLQMAVLSFEKDDDHNGHIDFITAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATTTATVSGLVALEMIKVTGGYPFEAYKNCFLNLAIPIVVFTETTEVRKTKIRNGISFTIWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLKLTMHKLVKPTTEKKYVDLTVSFAPDIDGDEDLPGPPVRYYFSHD 7sol C 2.25001 BS01 AMP D 1 G469 D497 K521 K544 V545 L568 D569 N570 T626 G411 D439 K463 K486 V487 L510 D511 N512 T568 6.2.1.45 0004792,0004839,0005515,0005524,0005737,0005829,0006511,0007612,0007626,0008641,0016567,0016779,0016874,0019780,0021764,0021766,0032446,0036211,0060996 A0AVT1 35986001 2101 MAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQAWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCVVLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEEPKEIFISNITQANPGIVTCLENHPHKLETGQFLTFREINGMTGLNGSIQQITVISPFSFSIGDTTELEPYLHGGIAVQVKTPKTVFFESLERQLKHPKCLIVDFSNPEAPLEIHTAMLALDQFQEKYSRKPNVGCQQDSEELLKLATSISETLEEKPDVNADIVHWLSWTAQGFLSPLAAAVGGVASQEVLKAVTGKFSPLCQWLYLEAADIVESLGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCPTTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEEEIPFATLKSFPAAIEHTIQWARDKFESSFSHKPSLFNKFWQTYSSAEEVLQKIQSGHSLEGCFQVIKLLSRRPRNWSQCVELARLKFEKYFNHKALQLLHCFPLDIRLKDGSLFWQSPKRPPSPIKFDLNEPLHLSFLQNAAKLYATVYCIPFAEEDLSADALLNILSEVKIQEFKPSEDERNAIFQLEKAILSNEATKSDLQMAVLSFEKDDDHNGHIDFITAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATTTATVSGLVALEMIKVTGGYPFEAYKNCFLNLAIPIVVFTETTEVRKTKIRNGISFTIWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLKLTMHKLVKPTTEKKYVDLTVSFAPDIDGDEDLPGPPVRYYFS 7sum A 2.9 BS04 AMP A 1 E566 Y567 K568 Y569 R573 E621 F660 M723 K725 W742 K744 E305 Y306 K307 Y308 R312 E360 F399 M462 K464 W481 K483 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 35790757 1001 DPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQ 7sx5 A 2.8 BS04 AMP A 1 K568 Y569 E621 F660 E720 M723 K746 K305 Y306 E358 F397 E457 M460 K483 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 35790757 1001 LDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS 7sxe A 3.0 BS04 AMP A 1 K568 Y569 R573 E621 F660 M723 K725 W742 K303 Y304 R308 E356 F395 M458 K460 W477 6.5.1.1 0003677,0003909,0003910,0005524,0006281,0006310,0071897 P18858 35790757 1001 LDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQI 7t29 A 1.5 BS01 AMP A 1 H91 D92 Q248 R336 L338 S341 T342 R345 H97 D98 Q254 R335 L337 S340 T341 R344 4.3.2.2 0003824,0004018,0005829,0006164,0006188,0006189,0009152,0016829,0044208,0070626 Q9I0K9 501 HHHHHHMQLSSLTAVSPVDGRYAGKTSSLRPIFSEYGLIRFRVMVEVRWLQRLAAHAGIPEVAPFSAEANALLDSLASDFQLEHAERIKEIERTTNHDVKAVEYLLKEQAAKLPELAAVSEFIHFACTSEDINNLSHALMLREGRDSVLLPLMRQIAEAIRELAVKLADVPMLSRTHGQPASPTTLGKELANVVYRLERQIKQVAGIELLGKINGAVGNYNAHLSAYPEVDWEANARQFIEGDLGLTFNPYTTQIEPHDYIAELFDAIARFNTILIDFDRDVWGYISLGYFKQKTVAGEIGVNPIDFENSEGNLGIANALFQHLASKLPISRWQRDLTDSTVLRNLGVGIAHSIIAYEASLKGIGKLELNAQRIAEDLDACWEVLAEPVQTVMRRYGVENPYEKLKELTRGISAEALQTFIEELAIPAEAKVELKKLTPAGYVGNAAAQAKRI 7tgl A 2.89 BS01 AMP A 1 G152 H153 Q274 M299 R303 H440 E442 N443 D460 E464 G152 H153 Q274 M299 R303 H440 E442 N443 D460 E464 0019290 35750210 604 MSLTDAVAHLSPERWEEANRLLVRKALAEFAHERLFTPEPADGQDGRYVVRSDDGLTSYRFTAVRRALDHWQVDAGSITRTRDGAELPLAALDFFIELRHTLGLSDEILPVYLEEISSTLSGTCYKLTKPQVTAAGLLEGGFQALESGMTEGHPCFVANNGRLGFGVDEYLAYAPETAHPVRLVWLAAHRSRAAFTAGAGIDYASFVRQELGEETVERFDGVLRGRGLDPADYLLIPVHPWQWWNKLSVTFAAEVARQNLVCLGESDDEYLAQQSIRTFFNATHPEKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLDRLIDNDPVLKSTGLSIIRERAAVGYRHLEYEAATDRYSPYRKMLAALWRESPVPALRDGESLTTMAALVHVDHEGRSVAGELIARSGLAPTAWLRHYLRAYYTPLLHSFYAYDLAFMPHGENTILVLKDGVVQRAVYKDIAEEIVVMDPDAVLPPEVRRVRAEVPEDMKLLSIFTDVFDCFFRFLAAGLATEEVLAEDDFWRTVAEVTREYQEAHPELDDRFRQYDLFAPEFALSCLNRLQLRDNRQMVDLADPSAALQLVGTLRNPLA 7tgl B 2.89 BS01 AMP B 1 G152 H153 Q274 N298 M299 R303 H440 E442 N443 D460 G152 H153 Q274 N298 M299 R303 H440 E442 N443 D460 0019290 35750210 607 MSLTDAVAHLSPERWEEANRLLVRKALAEFAHERLFTPEPADGQDGRYVVRSDDGLTSYRFTAVRRALDHWQVDAGSITRTRDGAELPLAALDFFIELRHTLGLSDEILPVYLEEISSTLSGTCYKLTKPQVTAAGLLEGGFQALESGMTEGHPCFVANNGRLGFGVDEYLAYAPETAHPVRLVWLAAHRSRAAFTAGAGIDYASFVRQELGEETVERFDGVLRGRGLDPADYLLIPVHPWQWWNKLSVTFAAEVARQNLVCLGESDDEYLAQQSIRTFFNATHPEKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLDRLIDNDPVLKSTGLSIIRERAAVGYRHLEYEAATDRYSPYRKMLAALWRESPVPALRDGESLTTMAALVHVDHEGRSVAGELIARSGLAPTAWLRHYLRAYYTPLLHSFYAYDLAFMPHGENTILVLKDGVVQRAVYKDIAEEIVVMDPDAVLPPEVRRVRAEVPEDMKLLSIFTDVFDCFFRFLAAGLATEEVLAEDDFWRTVAEVTREYQEAHPELDDRFRQYDLFAPEFALSCLNRLQLRDNRQMVDLADPSAALQLVGTLRNPLAGL 7tgl C 2.89 BS01 AMP C 1 G152 H153 Q274 N298 M299 R303 H440 E442 N443 D460 E464 G152 H153 Q274 N298 M299 R303 H440 E442 N443 D460 E464 0019290 35750210 604 MSLTDAVAHLSPERWEEANRLLVRKALAEFAHERLFTPEPADGQDGRYVVRSDDGLTSYRFTAVRRALDHWQVDAGSITRTRDGAELPLAALDFFIELRHTLGLSDEILPVYLEEISSTLSGTCYKLTKPQVTAAGLLEGGFQALESGMTEGHPCFVANNGRLGFGVDEYLAYAPETAHPVRLVWLAAHRSRAAFTAGAGIDYASFVRQELGEETVERFDGVLRGRGLDPADYLLIPVHPWQWWNKLSVTFAAEVARQNLVCLGESDDEYLAQQSIRTFFNATHPEKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLDRLIDNDPVLKSTGLSIIRERAAVGYRHLEYEAATDRYSPYRKMLAALWRESPVPALRDGESLTTMAALVHVDHEGRSVAGELIARSGLAPTAWLRHYLRAYYTPLLHSFYAYDLAFMPHGENTILVLKDGVVQRAVYKDIAEEIVVMDPDAVLPPEVRRVRAEVPEDMKLLSIFTDVFDCFFRFLAAGLATEEVLAEDDFWRTVAEVTREYQEAHPELDDRFRQYDLFAPEFALSCLNRLQLRDNRQMVDLADPSAALQLVGTLRNPLAG 7tgl D 2.89 BS01 AMP D 1 G152 H153 N298 M299 R303 H440 E442 N443 E464 G151 H152 N297 M298 R302 H439 E441 N442 E463 0019290 35750210 604 SLTDAVAHLSPERWEEANRLLVRKALAEFAHERLFTPEPADGQDGRYVVRSDDGLTSYRFTAVRRALDHWQVDAGSITRTRDGAELPLAALDFFIELRHTLGLSDEILPVYLEEISSTLSGTCYKLTKPQVTAAGLLEGGFQALESGMTEGHPCFVANNGRLGFGVDEYLAYAPETAHPVRLVWLAAHRSRAAFTAGAGIDYASFVRQELGEETVERFDGVLRGRGLDPADYLLIPVHPWQWWNKLSVTFAAEVARQNLVCLGESDDEYLAQQSIRTFFNATHPEKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLDRLIDNDPVLKSTGLSIIRERAAVGYRHLEYEAATDRYSPYRKMLAALWRESPVPALRDGESLTTMAALVHVDHEGRSVAGELIARSGLAPTAWLRHYLRAYYTPLLHSFYAYDLAFMPHGENTILVLKDGVVQRAVYKDIAEEIVVMDPDAVLPPEVRRVRAEVPEDMKLLSIFTDVFDCFFRFLAAGLATEEVLAEDDFWRTVAEVTREYQEAHPELDDRFRQYDLFAPEFALSCLNRLQLRDNRQMVDLADPSAALQLVGTLRNPLAGL 7tgl E 2.89 BS01 AMP E 1 G152 H153 Q274 N298 M299 R303 H440 E442 N443 E464 G152 H153 Q274 N298 M299 R303 H440 E442 N443 E464 0019290 35750210 605 MSLTDAVAHLSPERWEEANRLLVRKALAEFAHERLFTPEPADGQDGRYVVRSDDGLTSYRFTAVRRALDHWQVDAGSITRTRDGAELPLAALDFFIELRHTLGLSDEILPVYLEEISSTLSGTCYKLTKPQVTAAGLLEGGFQALESGMTEGHPCFVANNGRLGFGVDEYLAYAPETAHPVRLVWLAAHRSRAAFTAGAGIDYASFVRQELGEETVERFDGVLRGRGLDPADYLLIPVHPWQWWNKLSVTFAAEVARQNLVCLGESDDEYLAQQSIRTFFNATHPEKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLDRLIDNDPVLKSTGLSIIRERAAVGYRHLEYEAATDRYSPYRKMLAALWRESPVPALRDGESLTTMAALVHVDHEGRSVAGELIARSGLAPTAWLRHYLRAYYTPLLHSFYAYDLAFMPHGENTILVLKDGVVQRAVYKDIAEEIVVMDPDAVLPPEVRRVRAEVPEDMKLLSIFTDVFDCFFRFLAAGLATEEVLAEDDFWRTVAEVTREYQEAHPELDDRFRQYDLFAPEFALSCLNRLQLRDNRQMVDLADPSAALQLVGTLRNPLAG 7to3 A 2.74 BS01 AMP C 1 G385 A386 G387 D409 D411 T477 V482 G353 A354 G355 D377 D379 T445 V450 0008641 36755092 401 QVPAELQAALTLINNDPRMRTNNAWALSADKRWSLKFTAELSVPCSSFMPDNSVWHLVLWQEETLIRIEVYPDKSEGISATFQHQNYNFSDASTREWTSGNPALENTPTVFGRNLWGLEPEALLDRISWRLSRLLLWIDAAAQEKLATTGDAVELPAFPDQSPFTVIGFSEQIDDLPFWASKTGEWGFASSTGLPGAHGTLFLREFLDNKGKLIRTTKWSPFMRKGARTTNAVWSVLPTLPVLAPWQAPRTWQELSHCFAQCGLSLPDLFSDIGRSVRALRKQRAPGLLLLGFPLENKIGDEPARIHWLALRLQPLSQEPIRWVRTQNWAADQLRTRGEAANDIRSKKVLIIGAGSLGSMIAENLMRIGVVSQGILDADLLQTGNLSRHALTMTSVGHNKAAALVEHLNRILPDASARSFSCAFPPESEVAKNSLRQYDVIIDCTGDDGVLKSLAAFDWKSEKIFISLAMTWRAEGLFAFAASETSFPVTDASSRFNASASPEIDMDEARIEGIGAWHPVFPARADDVQLWAAVGTKFICRVVSAPGRIYEYFKQMPDGTVEKEPHEY 7to3 B 2.74 BS01 AMP D 1 G385 A386 G387 D409 D411 T477 V482 G353 A354 G355 D377 D379 T445 V450 0008641 36755092 401 QVPAELQAALTLINNDPRMRTNNAWALSADKRWSLKFTAELSVPCSSFMPDNSVWHLVLWQEETLIRIEVYPDKSEGISATFQHQNYNFSDASTREWTSGNPALENTPTVFGRNLWGLEPEALLDRISWRLSRLLLWIDAAAQEKLATTGDAVELPAFPDQSPFTVIGFSEQIDDLPFWASKTGEWGFASSTGLPGAHGTLFLREFLDNKGKLIRTTKWSPFMRKGARTTNAVWSVLPTLPVLAPWQAPRTWQELSHCFAQCGLSLPDLFSDIGRSVRALRKQRAPGLLLLGFPLENKIGDEPARIHWLALRLQPLSQEPIRWVRTQNWAADQLRTRGEAANDIRSKKVLIIGAGSLGSMIAENLMRIGVVSQGILDADLLQTGNLSRHALTMTSVGHNKAAALVEHLNRILPDASARSFSCAFPPESEVAKNSLRQYDVIIDCTGDDGVLKSLAAFDWKSEKIFISLAMTWRAEGLFAFAASETSFPVTDASSRFNASASPEIDMDEARIEGIGAWHPVFPARADDVQLWAAVGTKFICRVVSAPGRIYEYFKQMPDGTVEKEPHEY 7tqd A 2.9 BS01 AMP C 1 G385 A386 G387 D409 D411 T477 G11 A12 G13 D35 D37 T103 0008641 36755092 401 DIRSKKVLIIGAGSLGSMIAENLMRIGVVSQGILDADLLQTGNLSRHALTMTSVGHNKAAALVEHLNRILPDASARSFSCAFPPESEVAKNSLRQYDVIIDCTGDDGVLKSLAAFDWKSEKIFISLAMTWRAEGLFAFAASETSFPVTDASSRFNASASPEIDMDEARIEGIGAWHPVFPARADDVQLWAAVGTKFICRVVSAPGRIYEYFKQMPDGTVEKEPHEY 7tsq A 2.11 BS02 AMP D 1 I384 G387 L408 D409 K432 F456 T477 V482 I14 G17 L38 D39 K62 F86 T107 V112 0008641 36755092 401 EAANDIRSKKVLIIGAGSLGSMIAENLMRIGVVSQGILDADLLQTGNLSRHALTMTSVGHNKAAALVEHLNRILPDASARSFSCAFPPESEVAKNSLRQYDVIIDCTGDDGVLKSLAAFDWKSEKIFISLAMTWRAEGLFAFAASETSFPVTDASSRFNASAGAWHPVFPARADDVQLWAAVGTKFICRVVSAPGRIYEYFKQMPDGTVEKEPHEYGS 7tsq B 2.11 BS02 AMP C 1 I384 G385 G387 L408 D409 D411 K432 T477 V482 I13 G14 G16 L37 D38 D40 K61 T106 V111 0008641 36755092 401 AANDIRSKKVLIIGAGSLGSMIAENLMRIGVVSQGILDADLLQTGNLSRHALTMTSVGHNKAAALVEHLNRILPDASARSFSCAFPPESEVAKNSLRQYDVIIDCTGDDGVLKSLAAFDWKSEKIFISLAMTWRAEGLFAFAASETSFPVTDASSRFNASAFPARADDVQLWAAVGTKFICRVVSAPGRIYEYFKQMPDGTVEKEPHE 7u56 A 1.85 BS01 AMP A 1 F194 K196 E232 G234 I235 E239 F315 N325 F182 K184 E218 G220 I221 E225 F286 N296 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 A0A0H3GSI5 401 AKMRVGIVFGGKSAEHEVSLQSAKNIVEAIDKSRFDVVLLGIDKQGLWHINDAGNYLLNAQDPARIALRPSTVTLAQIPGREAQQLINAESGQPLAAIDVIFPIVHGTLGEDGSLQGMLRMANLPFVGSDVLGSAACMDKDVTKRLLRDAGLAVAPFITLTRANRAQFSFADVEAKLGLPLFVKPANQSVGVSKVKNEEQYHQAVALAFEFDHKVVVEQGIKGREIECAVLGNDHPQASTCGEIVLNAQVVVPAAIAPEINDKIRAIAVQAYQTLGCSGMARVDVFLTADNEVVINEINTLPGFTNISMYPKLWQASGLDYTSLITRLIELALERHAADRALKTSM 7u56 B 1.85 BS01 AMP B 1 K152 F194 K196 S203 E232 G234 I235 E239 F315 N325 K139 F181 K183 S188 E217 G219 I220 E224 F282 N292 6.3.2.4 0003824,0005524,0005737,0005829,0008360,0008716,0009252,0016874,0046872,0071555 A0A0H3GSI5 401 KMRVGIVFGGKSAEHEVSLQSAKNIVEAIDKSRFDVVLLGIDKQGLWHINDAGNYLLNAQDPARIALRPSTVTLAQIPGREAQQLINAESGQPLAAIDVIFPIVHGTLGEDGSLQGMLRMANLPFVGSDVLGSAACMDKDVTKRLLRDAGLAVAPFITLTRANRAQFSFADVEAKLGLPLFVKPANQSVGVSKVKNEEQYHQAVALAFEFDHKVVVEQGIKGREIECAVLGNDHPQASTCGEIVQVVVPAAIAPEINDKIRAIAVQAYQTLGCSGMARVDVFLTADNEVVINEINTLPGFTNISMYPKLWQASGLDYTSLITRLIELALERHAADRALKT 7uq1 A 1.72 BS01 AMP A 1 N32 Y34 P35 T41 N44 N82 S83 I86 V128 T131 I132 L133 D185 G187 N35 Y37 P38 T44 N47 N85 S86 I89 V131 T134 I135 L136 D188 G190 ? 0004371,0006071 Q2FZ58 35490779 301 GSHMISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTNMNLTMTSGREEVENNLSKNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIESESEINSKLLAESFQAGVETAYKAVMKPVEGTILTVAKDAAQAAIEKANNTEDCIELMEYIIVKANESLENTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKALKGEKV 7vka A 2.401 BS01 AMP A 1 S109 S110 I312 T314 Y338 A339 S340 S341 Y360 D427 F443 R446 S97 S98 I300 T302 Y326 A327 S328 S329 Y348 D413 F429 R432 6.3.2.- 0005737,0009733,0009734,0009826,0010252,0010279,0016874 Q9LSQ4 36454752 701 SDESLAEKNKNKLQFIEDVTTNADDVQRRVLEEILSRNADVEYLKRHGLEGRTDRETFKHIMPVVTYEDIQPEINRIANGDKSQVLCSNPISEFLTSSGTSGGERKLMPTIEEELDRRSLLYSLLMPVMDQFVPGLDKGKGMYFLFIKSESKTPGGLPARPVLTSYYKSSHFKNRPYDPYTNYTSPNQTILCSDSYQSMYSQMLCGLCQHKEVLRVGAVFASGFIRAIKFLEKHWPELARDIRTGTLSSEITDSSVREAVGEILKPDPKLADFVESECRKTSWQGIITRLWPNTKYVDVIVTGTMSQYIPTLDYYSNGLPLVCTMYASSECYFGVNLRPLCKPSEVSYTLIPNMAYFEFLPVHRNSGVTSSISLPKALKEQQELVDLVDVKLGQEYELVVTTYAGLYRYRVGDVLSVAGFKNNAPQFSFICRKNVVLSIDSDKTDEVELQNAVKNAVTHLVPFDASLSEYTSYADTSSIPGHYVLFWELCLNGNTPIPPSVFEDCCLTIEESLNSVYRQGRVSDKSIGPLEIKMVESGTFDKLMDYAISLGASINQYKTPRCVKFAPIIELLNSRVVDSYFSPKCPKWSPGHKQW 7vka B 2.401 BS01 AMP B 1 S110 I312 T314 Y338 A339 S340 S341 Y360 D427 F443 R446 S98 I300 T302 Y326 A327 S328 S329 Y348 D407 F423 R426 6.3.2.- 0005737,0009733,0009734,0009826,0010252,0010279,0016874 Q9LSQ4 36454752 701 SDESLAEKNKNKLQFIEDVTTNADDVQRRVLEEILSRNADVEYLKRHGLEGRTDRETFKHIMPVVTYEDIQPEINRIANGDKSQVLCSNPISEFLTSSGTSGGERKLMPTIEEELDRRSLLYSLLMPVMDQFVPGLDKGKGMYFLFIKSESKTPGGLPARPVLTSYYKSSHFKNRPYDPYTNYTSPNQTILCSDSYQSMYSQMLCGLCQHKEVLRVGAVFASGFIRAIKFLEKHWPELARDIRTGTLSSEITDSSVREAVGEILKPDPKLADFVESECRKTSWQGIITRLWPNTKYVDVIVTGTMSQYIPTLDYYSNGLPLVCTMYASSECYFGVNLRPLCKPSEVSYTLIPNMAYFEFLPVHRNSGVTSSIKEQQELVDLVDVKLGQEYELVVTTYAGLYRYRVGDVLSVAGFKNNAPQFSFICRKNVVLSIDSDKTDEVELQNAVKNAVTHLVPFDASLSEYTSYADTSSIPGHYVLFWELCLNGNTPIPPSVFEDCCLTIEESLNSVYRQGRVSDKSIGPLEIKMVESGTFDKLMDYAISLGASINQYKTPRCVKFAPIIELLNSRVVDSYFSPKCPKWSPGHKQW 7vyp A 2.88 BS04 AMP A 1 H137 D156 G157 G187 Y190 E204 G305 N309 H332 D333 H137 D156 G157 G187 Y190 E204 G305 N309 H332 D333 ? 0003824,0005524,0009058,0046872 Q84G19 36329057 715 MLVLGLNGNFSAADTDVVPQLGEVFFHDSAASLIRDGELVAAVEEERLNRIKKTTKFPLNAVRECLALAGARPEDVDAVGYYFPENHIDTVLNHLYTEYPRAPLRYSRELIRQRLKEGLGWDLPDEKLVYVPHHEAHAYSSYLHSGMDSALVLVLDGRGELHSGTVYRAEGTRLEKLADYPVPKSLGGLYLNATYLLGYGFGDEYKVMGLAPWGNPETYRDTFAKLYTLQDNGEYELHGNIMVPNLVSPLFYAEGFRPRRKGEPFTQAHRDFAAALQETVEKIVLHILEYWAKTSGHSRLCFGGGVAHNSSLNGLILKSGLFDEVFVHPASHDAGAGEGAAYAAAASLGTLERPGKRLLSASLGPALGGREQIRARLADWAPLIDVEFPDDAVETAAGLLAEGQVLGWAYGRSEFGPRALGHRSIVADARPEENRTRINAMVKKREGFRPFAPVVTAEAARDYFDLSGADGNHEFMSFVVPVLPERRTELGAVTHVDGTARVQVVSAESGERFHRLVRRFGELTGTPVLLNTSFNNNAEPIVQSLDDVVTSFLTTDLDVLVVEDCLVRGKASPDLGVLVPRFRPVTRLVERRTAGPDASAGAKTHEIHLDYDGGPSAKVSPELYELLGAVDGTTTLGDLAKTVGGLSDALATEVFALWEQRFLTLAPAGDIGPL 7vzy A 2.81 BS03 AMP A 1 H137 D156 G157 G187 Y190 E204 G305 N309 H332 D333 H137 D156 G157 G187 Y190 E204 G305 N309 H332 D333 ? 0003824,0005524,0009058,0046872 Q84G19 36329057 703 MLVLGLNGNFSAADTDVVPQLGEVFFHDSAASLIRDGELVAAVEEERLNRIKKTTKFPLNAVRECLALAGARPEDVDAVGYYFPENHIDTVLNHLYTEYPRAPLRYSRELIRQRLKEGLGWDLPDEKLVYVPHHEAHAYSSYLHSGMDSALVLVLDGRGELHSGTVYRAEGTRLEKLADYPVPKSLGGLYLNATYLLGYGFGDEYKVMGLAPWGNPETYRDTFAKLYTLQDNGEYELHGNIMVPNLVSPLFYAEGFRPRRKGEPFTQAHRDFAAALQETVEKIVLHILEYWAKTSGHSRLCFGGGVAHNSSLNGLILKSGLFDEVFVHPASHDAGAGEGAAYAAAASLGTLERPGKRLLSASLGPALGGREQIRARLADWAPLIDVEFPDDAVETAAGLLAEGQVLGWAYGRSEFGPRALGHRSIVADARPEENRTRINAMVKKREGFRPFAPVVTAEAARDYFDLSGADGNHEFMSFVVPVLPERRTELGAVTHVDGTARVQVVSAESGERFHRLVRRFGELTGTPVLLNTSFNNNAEPIVQSLDDVVTSFLTTDLDVLVVEDCLVRGKASPDLGVLVPRFRPVTRLVERRTAGPDASAGAKTHEIHLDYDGGPSAKVSPELYELLGAVDGTTTLGDLAKTVGGLSDALATEVFALWEQRFLTLAPAGDIGPL 7vzy B 2.81 BS04 AMP B 1 H137 D156 G157 G187 Y190 E204 G305 N309 H332 D333 H137 D156 G157 G187 Y190 E204 G305 N309 H332 D333 ? 0003824,0005524,0009058,0046872 Q84G19 36329057 703 MLVLGLNGNFSAADTDVVPQLGEVFFHDSAASLIRDGELVAAVEEERLNRIKKTTKFPLNAVRECLALAGARPEDVDAVGYYFPENHIDTVLNHLYTEYPRAPLRYSRELIRQRLKEGLGWDLPDEKLVYVPHHEAHAYSSYLHSGMDSALVLVLDGRGELHSGTVYRAEGTRLEKLADYPVPKSLGGLYLNATYLLGYGFGDEYKVMGLAPWGNPETYRDTFAKLYTLQDNGEYELHGNIMVPNLVSPLFYAEGFRPRRKGEPFTQAHRDFAAALQETVEKIVLHILEYWAKTSGHSRLCFGGGVAHNSSLNGLILKSGLFDEVFVHPASHDAGAGEGAAYAAAASLGTLERPGKRLLSASLGPALGGREQIRARLADWAPLIDVEFPDDAVETAAGLLAEGQVLGWAYGRSEFGPRALGHRSIVADARPEENRTRINAMVKKREGFRPFAPVVTAEAARDYFDLSGADGNHEFMSFVVPVLPERRTELGAVTHVDGTARVQVVSAESGERFHRLVRRFGELTGTPVLLNTSFNNNAEPIVQSLDDVVTSFLTTDLDVLVVEDCLVRGKASPDLGVLVPRFRPVTRLVERRTAGPDASAGAKTHEIHLDYDGGPSAKVSPELYELLGAVDGTTTLGDLAKTVGGLSDALATEVFALWEQRFLTLAPAGDIGPLADDG 7wjv A 1.724 BS01 AMP A 1 V17 E20 G21 A24 G26 T27 E29 L30 K112 Y113 M177 V9 E12 G13 A16 G18 T19 E21 L22 K99 Y100 M164 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 35786925 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 7wjv B 1.724 BS03 AMP B 1 V17 E20 G21 A24 G26 T27 E29 L30 K112 Y113 M177 V9 E12 G13 A16 G18 T19 E21 L22 K104 Y105 M169 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 35786925 502 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 7wjv C 1.724 BS01 AMP C 1 V17 E20 G21 A24 T27 E29 L30 K112 Y113 M177 V9 E12 G13 A16 T19 E21 L22 K104 Y105 M168 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 35786925 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 7wjv D 1.724 BS01 AMP D 1 V17 E20 G21 A24 T27 E29 L30 K112 Y113 R140 M177 V9 E12 G13 A16 T19 E21 L22 K97 Y98 R125 M162 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 P09467 35786925 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 7xbt A 1.84 BS01 AMP A 1 G277 E278 Y302 G303 D393 F408 K417 R422 G277 E278 Y302 G303 D393 F408 K417 R422 ? A6YEH8 36278314 601 VTADAALEPDERAAWLAYNDTAEDFPGPHLLARLDAVAREHPDRPAVHAVDGVWTYRELHRRADAVAAFLAARGVRPGSVVAIAATRALAPYAALLGVLKAGCAYVPVNPDDPADRVAFVLADAGATPLLLDTDPASLPAAPAPDVPHEPDRVCYVIYTSGSTGRPKGVVMAERAVDNLTHWVVRRHDVRPDDRLGQTAPLTFDPSVQQVFPAWATGACLVTVPDDVQRDPAAFLDWLRAERVTHLDLVTSHWVHLLNAAEARPAELPDLRWIIIGGETYYYHQTHRWHRVVSSPARLNTIYGPTEAAVNATEHLTEPDLDHGQVPIGVPLPNYRLYALDDDGRLCPPGITGEIHIAGAGLARGYRSAEATAKAFHELEVHSGRTERLYRTGDLARLVRHADRWALEFQGRVDSQVKISGYRVELEEVDAAVKAVPGVRDAAVVVRGAEQLVCCYVGDVPPDRLRSRLTERLPAYLVPHLLVPVEAL 7xmv A 2.6 BS03 AMP A 1 E133 F147 S149 V175 A179 E131 F145 S147 V173 A177 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006164,0009156,0009165,0016301,0016310,0034214,0042301,0042802,0043531,0044249,0046872 P0A717 35736577 405 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH 7xmv A 2.6 BS04 AMP C 1 R99 V101 R102 R97 V99 R100 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006164,0009156,0009165,0016301,0016310,0034214,0042301,0042802,0043531,0044249,0046872 P0A717 35736577 405 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH 7xmv B 2.6 BS02 AMP D 1 R99 V101 R102 R97 V99 R100 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006164,0009156,0009165,0016301,0016310,0034214,0042301,0042802,0043531,0044249,0046872 P0A717 35736577 405 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH 7xmv B 2.6 BS05 AMP B 1 E133 F147 S149 V175 A179 E131 F145 S147 V173 A177 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006164,0009156,0009165,0016301,0016310,0034214,0042301,0042802,0043531,0044249,0046872 P0A717 35736577 405 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH 7xmv C 2.6 BS01 AMP A 1 R99 V101 R102 R97 V99 R100 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006164,0009156,0009165,0016301,0016310,0034214,0042301,0042802,0043531,0044249,0046872 P0A717 35736577 405 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH 7xmv C 2.6 BS04 AMP C 1 E133 F147 S149 V175 A179 E131 F145 S147 V173 A177 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006164,0009156,0009165,0016301,0016310,0034214,0042301,0042802,0043531,0044249,0046872 P0A717 35736577 405 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH 7xmv D 2.6 BS04 AMP D 1 E133 F147 S149 V175 A179 E131 F145 S147 V173 A177 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006164,0009156,0009165,0016301,0016310,0034214,0042301,0042802,0043531,0044249,0046872 P0A717 35736577 405 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH 7xmv D 2.6 BS05 AMP B 1 R99 V101 R102 R97 V99 R100 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006164,0009156,0009165,0016301,0016310,0034214,0042301,0042802,0043531,0044249,0046872 P0A717 35736577 405 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH 7xmv E 2.6 BS03 AMP E 1 E133 F147 S149 V175 A179 E131 F145 S147 V173 A177 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006164,0009156,0009165,0016301,0016310,0034214,0042301,0042802,0043531,0044249,0046872 P0A717 35736577 405 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH 7xmv E 2.6 BS05 AMP F 1 R99 V101 R102 R97 V99 R100 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006164,0009156,0009165,0016301,0016310,0034214,0042301,0042802,0043531,0044249,0046872 P0A717 35736577 405 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH 7xmv F 2.6 BS02 AMP E 1 R99 V101 R102 R97 V99 R100 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006164,0009156,0009165,0016301,0016310,0034214,0042301,0042802,0043531,0044249,0046872 P0A717 35736577 405 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH 7xmv F 2.6 BS05 AMP F 1 E133 F147 S149 V175 A179 E131 F145 S147 V173 A177 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006164,0009156,0009165,0016301,0016310,0034214,0042301,0042802,0043531,0044249,0046872 P0A717 35736577 405 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH 7ywk A 1.39 BS01 AMP A 1 G300 S301 A320 Y321 G322 L323 T324 D412 F424 G273 S274 A293 Y294 G295 L296 T297 D385 F397 5.1.1.11 P09095 36070491 502 HALVPYAQGKSIHQLFEEQAEAFPDRVAIVFENRRLSYQELNRKANQLARALLEKGVQTDSIVGVMMEKSIENVIAILAVLKAGGAYVPIDIEYPRDRIQYILQDSQTKIVLTQKSVSQLVHDVGYSGEVVVLDEEQLDARETANLHQPSKPTDLAYVIYTSGTTGKPKGTMLEHKGIANLQSFFQNSFGVTEQDRIGLFASMSFAASVSEMFMALLSGASLYILSKQTIHDFAAFEHYLSENELTIITLPPTYLTHLTPERITSLRIMITAGSASSAPLVNKWKDKLRYINAYGLTETSCSATIWEAPSNQLSVQSVPIGKPIQNTHIYIVNEDLQLLPTGSEGELCIGGVGLARGYWNRPDLTAEKFVDNPFVPGEKMYRTGDLAKWLTDGTIEFLGRI 7ywk B 1.39 BS01 AMP B 1 G300 S301 A302 A320 Y321 G322 L323 T324 D412 G271 S272 A273 A291 Y292 G293 L294 T295 D383 5.1.1.11 P09095 36070491 502 LVPYAQGKSIHQLFEEQAEAFPDRVAIVFENRRLSYQELNRKANQLARALLEKGVQTDSIVGVMMEKSIENVIAILAVLKAGGAYVPIDIEYPRDRIQYILQDSQTKIVLTQKSVSQLVHDVGYSGEVVVLDEEQLDARETANLHQPSKPTDLAYVIYTSGTTGKPKGTMLEHKGIANLQSFFQNSFGVTEQDRIGLFASMSFAASVSEMFMALLSGASLYILSKQTIHDFAAFEHYLSENELTIITLPPTYLTHLTPERITSLRIMITAGSASSAPLVNKWKDKLRYINAYGLTETSCSATIWEAPSNQLSVQSVPIGKPIQNTHIYIVNEDLQLLPTGSEGELCIGGVGLARGYWNRPDLTAEKFVDNPFVPGEKMYRTGDLAKWLTDGTIEFLGRI 7zd6 k 3.16 BS01 AMP k 1 I31 K35 S36 E53 L79 Y83 Q97 R104 R126 F134 I31 K35 S36 E53 L79 Y83 Q97 R104 R126 F134 ? 0005737,0005739,0005759,0006120 A0A8N7XJK5 36104567 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 7zdh k 3.46 BS01 AMP k 1 I31 S36 E53 Y83 Q97 L100 R104 R126 F134 I31 S36 E53 Y83 Q97 L100 R104 R126 F134 ? 0005737,0005739,0005759,0006120 A0A8N7XJK5 36104567 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 7zdm k 3.44 BS01 AMP k 1 I31 S36 E53 Y83 Q97 L100 R104 R126 F134 I31 S36 E53 Y83 Q97 L100 R104 R126 F134 ? 0005737,0005739,0005759,0006120 A0A8N7XJK5 36104567 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 7zdp k 3.88 BS01 AMP k 1 I31 S36 E53 L79 Y83 R126 F134 I31 S36 E53 L79 Y83 R126 F134 ? 0005737,0005739,0005759,0006120 A0A8N7XJK5 36104567 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 7zeb k 3.8 BS01 AMP k 1 I31 S36 Y83 L100 R104 R126 F134 I31 S36 Y83 L100 R104 R126 F134 ? 0005737,0005739,0005759,0006120 A0A8N7XJK5 36104567 501 LQYGPLAYILGEKTTKKMTENSKLITVDGNICSGKSKLAKEVAEKLGLKHFPEAGIHYADSTTGDGKPLPVRFSGNCSLEKFYDDPKSNDGNSYRLQAWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVDHYNQVKKVTVCEYLPPHVVIYVDVPVSEVQSRIQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEKVVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNYTSIPVFLPEVTIGAHQSDRVFQEFTELPGRKYRAGYNEDVGDKWIWLK 8a8k A 3.1 BS01 AMP A 1 H6 F37 N59 H77 S229 R233 Y258 R260 N284 A285 G286 V291 G293 H8 F39 N61 H79 S231 R235 Y260 R262 N286 A287 G288 V293 G295 37277534 401 SHMLVIHHWDTDGITSAALTIKALGLDDFINIVPPIGEFRFDGRVKKHIEEAEKVYILDLNLPQEVEDVEKDTVFIDHHLQKKIKNPKVRQVNPILERMNGKEFPSASFVVSNHFSLWNSWSSLGAVGDIGNKAFEIPKTLELLKTEGLTKNEALKLVQLIDSNYITMDRSAAEKAVELVLNRPLKELLEYEPWIKNLEEIERTIKDVLSGIEVKNDIAFIEYSSPFNIISKIARKAVWEMGYNGAVVLNRSFHEKAQLYFRISPDLKEKIDMEGIIQILKNRGFNAGGKSEVLGIIFEKNRIDEVLGIINGYLASL 8a8k B 3.1 BS01 AMP B 1 H6 F37 H77 S229 Y258 R260 N284 A285 G286 V291 G293 H7 F38 H78 S230 Y259 R261 N285 A286 G287 V292 G294 37277534 401 HMLVIHHWDTDGITSAALTIKALGLDDFINIVPPIGEFRFDGRVKKHIEEAEKVYILDLNLPQEVEDVEKDTVFIDHHLQKKIKNPKVRQVNPILERMNGKEFPSASFVVSNHFSLWNSWSSLGAVGDIGNKAFEIPKTLELLKTEGLTKNEALKLVQLIDSNYITMDRSAAEKAVELVLNRPLKELLEYEPWIKNLEEIERTIKDVLSGIEVKNDIAFIEYSSPFNIISKIARKAVWEMGYNGAVVLNRSFHEKAQLYFRISPDLKEKIDMEGIIQILKNRGFNAGGKSEVLGIIFEKNRIDEVLGIINGYLASL 8a8k C 3.1 BS01 AMP C 1 H6 F37 N59 H77 S229 R233 Y258 R260 N284 A285 G286 V291 G293 H7 F38 N60 H78 S230 R234 Y259 R261 N285 A286 G287 V292 G294 37277534 401 HMLVIHHWDTDGITSAALTIKALGLDDFINIVPPIGEFRFDGRVKKHIEEAEKVYILDLNLPQEVEDVEKDTVFIDHHLQKKIKNPKVRQVNPILERMNGKEFPSASFVVSNHFSLWNSWSSLGAVGDIGNKAFEIPKTLELLKTEGLTKNEALKLVQLIDSNYITMDRSAAEKAVELVLNRPLKELLEYEPWIKNLEEIERTIKDVLSGIEVKNDIAFIEYSSPFNIISKIARKAVWEMGYNGAVVLNRSFHEKAQLYFRISPDLKEKIDMEGIIQILKNRGFNAGGKSEVLGIIFEKNRIDEVLGIINGYLASL 8a8k D 3.1 BS01 AMP D 1 F37 N59 H77 S229 R233 Y258 R260 N284 A285 G286 G293 F38 N60 H78 S230 R234 Y259 R261 N285 A286 G287 G294 37277534 401 HMLVIHHWDTDGITSAALTIKALGLDDFINIVPPIGEFRFDGRVKKHIEEAEKVYILDLNLPQEVEDVEKDTVFIDHHLQKKIKNPKVRQVNPILERMNGKEFPSASFVVSNHFSLWNSWSSLGAVGDIGNKAFEIPKTLELLKTEGLTKNEALKLVQLIDSNYITMDRSAAEKAVELVLNRPLKELLEYEPWIKNLEEIERTIKDVLSGIEVKNDIAFIEYSSPFNIISKIARKAVWEMGYNGAVVLNRSFHEKAQLYFRISPDLKEKIDMEGIIQILKNRGFNAGGKSEVLGIIFEKNRIDEVLGIINGYLASL 8a8k E 3.1 BS01 AMP E 1 F37 H77 S229 Y258 N284 A285 G286 V291 G293 F38 H78 S230 Y259 N285 A286 G287 V292 G294 37277534 401 HMLVIHHWDTDGITSAALTIKALGLDDFINIVPPIGEFRFDGRVKKHIEEAEKVYILDLNLPQEVEDVEKDTVFIDHHLQKKIKNPKVRQVNPILERMNGKEFPSASFVVSNHFSLWNSWSSLGAVGDIGNKAFEIPKTLELLKTEGLTKNEALKLVQLIDSNYITMDRSAAEKAVELVLNRPLKELLEYEPWIKNLEEIERTIKDVLSGIEVKNDIAFIEYSSPFNIISKIARKAVWEMGYNGAVVLNRSFHEKAQLYFRISPDLKEKIDMEGIIQILKNRGFNAGGKSEVLGIIFEKNRIDEVLGIINGYLASL 8a8k F 3.1 BS01 AMP F 1 F37 N59 H77 S229 R233 Y258 R260 N284 G286 G293 F39 N61 H79 S231 R235 Y260 R262 N286 G288 G295 37277534 502 SHMLVIHHWDTDGITSAALTIKALGLDDFINIVPPIGEFRFDGRVKKHIEEAEKVYILDLNLPQEVEDVEKDTVFIDHHLQKKIKNPKVRQVNPILERMNGKEFPSASFVVSNHFSLWNSWSSLGAVGDIGNKAFEIPKTLELLKTEGLTKNEALKLVQLIDSNYITMDRSAAEKAVELVLNRPLKELLEYEPWIKNLEEIERTIKDVLSGIEVKNDIAFIEYSSPFNIISKIARKAVWEMGYNGAVVLNRSFHEKAQLYFRISPDLKEKIDMEGIIQILKNRGFNAGGKSEVLGIIFEKNRIDEVLGIINGYLASL 8bik C 2.5 BS01 AMP C 1 K170 I240 S242 F244 D245 R269 V276 L277 V297 H298 R299 K146 I216 S218 F220 D221 R245 V252 L253 V273 H274 R275 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 401 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 8bik C 2.5 BS02 AMP C 2 H151 T200 I204 A205 V225 S226 H298 I312 S314 S316 D317 H127 T176 I180 A181 V201 S202 H274 I288 S290 S292 D293 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 402 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 8bik F 2.5 BS01 AMP F 1 M85 T87 T89 Y121 V130 H151 R152 M60 T62 T64 Y96 V105 H126 R127 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 401 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 8bik F 2.5 BS02 AMP F 2 R70 K170 I240 S242 F244 D245 R269 F273 V276 L277 V297 R299 R45 K145 I215 S217 F219 D220 R244 F248 V251 L252 V272 R274 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 402 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 8bik F 2.5 BS03 AMP F 3 H151 T200 I204 A205 V225 S226 H298 S314 S316 D317 H126 T175 I179 A180 V200 S201 H273 S289 S291 D292 ? 0004672,0004691,0005515,0005524,0005634,0005654,0005737,0005829,0006110,0006468,0006633,0007165,0007283,0008603,0010628,0016020,0016208,0019887,0019901,0031588,0031669,0043531,0045860,0051170 P54619 403 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 8biq A 2.8 BS01 AMP A 1 G328 E329 P330 G352 Q353 T354 D435 F447 K456 R461 G320 E321 P322 G344 Q345 T346 D427 F439 K448 R453 6.2.1.1,6.2.1.17,6.2.1.2,6.2.1.40 0003987,0004321,0005524,0006631,0006633,0006637,0015645,0016020,0016874,0031956,0050218 A4YDT1 601 TVQDFFRKFIEFQNSPNEKSLQEIVKLVGQLDLRRFNWVRDVFEDIHVKERGSKTALIWRDINTGEEAKLSYHELSLMSNRVLSTLRKHGLKKGDVVYLMTKVHPMHWAVFLAVIKGGFVMVPSATNLTVAEMKYRFSDLKPSAIISDSLRASVMEEALGSLKVEKFLIDGKRETWNSLEDESSNAEPEDTRGEDVIINYFTSGTTGMPKRVIHTAVSYPVGSITTASIVGVRESDLHLNLSATGWAKFAWSSFFSPLLVGATVVGINYEGKLDTRRYLGEVENLGVTSFCAPPTAWRQFITLDLDQFRFERLRSVVSAGEPLNPEVIKIWKDKFNLTIRDFYGQTETTAMVGNFPFLKVKPGSMGKPHPLYDIRLLDDEGKEITKPYEVGHITVKLNPRPIGLFLGYSDEKKNMESFREGYYYTGDKAYFDEEGYFYFVGRGDDVIKTSDYRVGPFEVESALLEHPAVAEAAVVGVPDTVRWQLVKAYIVLKKGYMPSKELAEEIREKMKTLLSPYKVPRIIEFVDELPKTISGKIRRVELRKREEEKRKKGEVGQNEYVF 8biq C 2.8 BS01 AMP C 1 G328 E329 P330 D349 G352 Q353 T354 D435 F447 K456 G319 E320 P321 D340 G343 Q344 T345 D426 F438 K447 6.2.1.1,6.2.1.17,6.2.1.2,6.2.1.40 0003987,0004321,0005524,0006631,0006633,0006637,0015645,0016020,0016874,0031956,0050218 A4YDT1 601 VQDFFRKFIEFQNSPNEKSLQEIVKLVGQLDLRRFNWVRDVFEDIHVKERGSKTALIWRDINTGEEAKLSYHELSLMSNRVLSTLRKHGLKKGDVVYLMTKVHPMHWAVFLAVIKGGFVMVPSATNLTVAEMKYRFSDLKPSAIISDSLRASVMEEALGSLKVEKFLIDGKRETWNSLEDESSNAEPEDTRGEDVIINYFTSGTTGMPKRVIHTAVSYPVGSITTASIVGVRESDLHLNLSATGWAKFAWSSFFSPLLVGATVVGINYEGKLDTRRYLGEVENLGVTSFCAPPTAWRQFITLDLDQFRFERLRSVVSAGEPLNPEVIKIWKDKFNLTIRDFYGQTETTAMVGNFPFLKVKPGSMGKPHPLYDIRLLDDEGKEITKPYEVGHITVKLNPRPIGLFLGYSDEKKNMESFREGYYYTGDKAYFDEEGYFYFVGRGDDVIKTSDYRVGPFEVESALLEHPAVAEAAVVGVPDTVRWQLVKAYIVLKKGYMPSKELAEEIREKMKTLLSPYKVPRIIEFVDELPRRVELRKREEEKRKKGEVGQNEYVF 8biq D 2.8 BS01 AMP D 1 G328 E329 P330 D349 Y351 G352 Q353 T354 D435 F447 K456 G319 E320 P321 D340 Y342 G343 Q344 T345 D426 F438 K447 6.2.1.1,6.2.1.17,6.2.1.2,6.2.1.40 0003987,0004321,0005524,0006631,0006633,0006637,0015645,0016020,0016874,0031956,0050218 A4YDT1 601 VQDFFRKFIEFQNSPNEKSLQEIVKLVGQLDLRRFNWVRDVFEDIHVKERGSKTALIWRDINTGEEAKLSYHELSLMSNRVLSTLRKHGLKKGDVVYLMTKVHPMHWAVFLAVIKGGFVMVPSATNLTVAEMKYRFSDLKPSAIISDSLRASVMEEALGSLKVEKFLIDGKRETWNSLEDESSNAEPEDTRGEDVIINYFTSGTTGMPKRVIHTAVSYPVGSITTASIVGVRESDLHLNLSATGWAKFAWSSFFSPLLVGATVVGINYEGKLDTRRYLGEVENLGVTSFCAPPTAWRQFITLDLDQFRFERLRSVVSAGEPLNPEVIKIWKDKFNLTIRDFYGQTETTAMVGNFPFLKVKPGSMGKPHPLYDIRLLDDEGKEITKPYEVGHITVKLNPRPIGLFLGYSDEKKNMESFREGYYYTGDKAYFDEEGYFYFVGRGDDVIKTSDYRVGPFEVESALLEHPAVAEAAVVGVPDTVRWQLVKAYIVLKKGYMPSKELAEEIREKMKTLLSPYKVPRIIEFVDELPKTISGKIRRVELRKREEEKRKKGEVGQNEYVF 8bxg A 3.16 BS02 AMP A 1 F407 R409 D429 H430 D431 A450 I471 R496 F394 R396 D416 H417 D418 A437 I458 R483 ? 0000166,0005515,0005886,0006812,0006813,0006885,0008324,0009636,0015079,0015297,0015503,0015643,0016020,0019899,0042542,0042803,0051453,0051454,0051595,0055085,0071805,1902600,1903103 P03819 38834573 602 MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAM 8bxg B 3.16 BS02 AMP B 1 F407 G408 R409 D429 H430 I471 D472 R496 F393 G394 R395 D415 H416 I457 D458 R482 ? 0000166,0005515,0005886,0006812,0006813,0006885,0008324,0009636,0015079,0015297,0015503,0015643,0016020,0019899,0042542,0042803,0051453,0051454,0051595,0055085,0071805,1902600,1903103 P03819 38834573 602 MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAM 8by2 A 3.18 BS02 AMP A 1 F407 R409 H430 D431 D449 A450 I471 R496 F395 R397 H418 D419 D437 A438 I459 R484 ? 0000166,0005515,0005886,0006812,0006813,0006885,0008324,0009636,0015079,0015297,0015503,0015643,0016020,0019899,0042542,0042803,0051453,0051454,0051595,0055085,0071805,1902600,1903103 P03819 38834573 602 MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAM 8by2 B 3.18 BS03 AMP B 1 G406 F407 G408 R409 D429 H430 D449 I471 D472 R496 G392 F393 G394 R395 D415 H416 D435 I457 D458 R482 ? 0000166,0005515,0005886,0006812,0006813,0006885,0008324,0009636,0015079,0015297,0015503,0015643,0016020,0019899,0042542,0042803,0051453,0051454,0051595,0055085,0071805,1902600,1903103 P03819 38834573 602 MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAM 8c4n A 1.75 BS01 AMP A 1 L31 D71 G72 Y87 L88 T102 L28 D68 G69 Y84 L85 T99 2.7.7.85 0004016,0006171 Q8Y5E4 37223749 201 RIEREQHHLIESIEKSTQYMAKRRIGALISVARDTGMDDYIETGIPLNAKISSQLLINIFIPNTPLHDGAVIIKGNEIASAASYLPLSDSPFLSKELGTRHRAALGISEVTDSITIVVSEETGGISLTKGGELFRDVSEEELHKILLKELVT 8c4n B 1.75 BS01 AMP B 1 L31 D71 G72 Y87 L88 T102 A106 L29 D69 G70 Y85 L86 T100 A104 2.7.7.85 0004016,0006171 Q8Y5E4 37223749 201 SRIEREQHHLIESIEKSTQYMAKRRIGALISVARDTGMDDYIETGIPLNAKISSQLLINIFIPNTPLHDGAVIIKGNEIASAASYLPLSDSPFLSKELGTRHRAALGISEVTDSITIVVSEETGGISLTKGGELFRDVSEEELHKILLKELVTVTAKKPSIFSKWK 8cp4 A 3.19 BS02 AMP A 1 Y28 T51 I52 F57 K100 F138 Y24 T47 I48 F53 K96 F134 ? 0000166,0016783,0046872,0051539 Q6LXV7 38100250 302 EKGLLEKYNSLLEFFKNKKVIVAYSGGVDSTLISKIASDNAQTLAVTIDNGFFSENVIKKAENRAKKYNIPQKTIKIDYLNEITSKDLENRCYNCKKRIAEELKRIKNELNYDIIVDGTIYDDIFEDRPGIKAFNESNIISPLSNLKFSKNDVFELSNYLKIDIPKKDTCMATRILSAPISKENMAKSNLAEEFIKLNFHIESYLRVRYLENIAIIELTKNESEKIFDNDSIERINTELKKIGFEKVVLDLNFKG 8dbk B 2.1 BS02 AMP B 1 R96 Q97 N200 R95 Q96 N199 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006144,0006164,0006221,0006796,0007399,0009156,0009165,0016301,0016310,0034418,0042802,0042803,0044249,0046101,0046872,0090407 P60891 36747094 402 PNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVP 8dbk F 2.1 BS02 AMP B 1 F35 E39 F34 E38 2.7.6.1 0000287,0002189,0004749,0005515,0005524,0005737,0005829,0006015,0006144,0006164,0006221,0006796,0007399,0009156,0009165,0016301,0016310,0034418,0042802,0042803,0044249,0046101,0046872,0090407 P60891 36747094 402 PNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKEDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVP 8dqj A 1.54 BS01 AMP A 1 R150 L159 F162 E218 V219 C220 S221 G245 R248 R148 L151 F154 E201 V202 C203 S204 G221 R224 ? 0004812,0005524,0046872 A0A3G3IHP7 36395426 302 VKYTDAQIQRLREYGNGTYEQKVFEDLASRDAAFSKEMSVASTDNEKKIKGMIANPSRHGLTQLMNDIADALVAEGFIEVRTPIFISKDALARMTITEDKPLFKQVFWIDEKRALRPMLAPNLYSVMRDLRDHTDGPVKIFEMGSCFRKELEEFTMLSLCDMGPRGDATEVLKNYISVVMKAAGLPDYDLVTIDVEINGQEVCSAAVGPDVHEPTSGAGFGLERLLTIREKYSTVKKGGASISYLNGAKIN 8f5x A 1.7 BS01 AMP A 1 W7 N65 R68 D112 H129 W8 N66 R69 D113 H130 4.6.1.18 0003676 P10153 38588810 204 MKPPQFTWAQWFETQHINMTSQQCTNAMQVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII 8ghr A 3.2 BS03 AMP A 1 A256 Y340 Y371 H535 A70 Y154 Y185 H349 ?,3.1.4.1,3.6.1.9 0003676,0016787,0046872 P0DOX5,P22413 37400538 1303 EKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKAFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVYTPKHPKEVHPLVQCPFTRNPRDNLGCSCNPSILPIEDFQTQFNLTVAEEKIIKHETLPYGRPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPLSPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTLLRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCENLDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFYQQRKEPVSDILKLKTHLPTF 8ghr B 3.2 BS03 AMP B 1 A256 Y340 Y371 H535 A70 Y154 Y185 H349 ?,3.1.4.1,3.6.1.9 0003676,0016787,0046872 P0DOX5,P22413 37400538 1303 EKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKAFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVYTPKHPKEVHPLVQCPFTRNPRDNLGCSCNPSILPIEDFQTQFNLTVAEEKIIKHETLPYGRPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPLSPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTLLRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCENLDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFYQQRKEPVSDILKLKTHLPTF 8gpb A 2.2 BS02 AMP A 1 Q72 Y75 R309 R310 Q62 Y65 R299 R300 H377 K568 R569 K574 T676 K680 H367 K558 R559 K564 T666 K670 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 Kd=250uM -logKd/Ki=3.60, Kd=0.25mM P00489 1900534 930 KQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDEKIP 8gpb A 2.2 BS03 AMP A 2 N282 F285 P611 G612 Y613 N272 F275 P601 G602 Y603 H377 K568 R569 K574 T676 K680 H367 K558 R559 K564 T666 K670 2.4.1.1 0000166,0004645,0005737,0005975,0005977,0005980,0008184,0016757,0030170,0098723,0102250,0102499 Kd=250uM -logKd/Ki=3.60, Kd=0.25mM P00489 1900534 940 KQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVIPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDEKIP 8hcc A 2.0 BS01 AMP A 1 D18 L19 E20 A21 G23 I84 Y129 H195 D15 L16 E17 A18 G20 I81 Y126 H190 3.1.11.2 0003676,0008408 Q91XB0 37870446 301 QTLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASSPSGSRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYG 8hcc B 2.0 BS01 AMP B 1 D18 E20 A21 G23 L24 A81 I84 Y129 H195 D14 E16 A17 G19 L20 A77 I80 Y125 H188 3.1.11.2 0003676,0008408 Q91XB0 37870446 301 TLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASSNGSRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYG 8hcc C 2.0 BS01 AMP C 1 D18 E20 A21 G23 L24 A81 I84 Y129 H195 D14 E16 A17 G19 L20 A77 I80 Y125 H186 3.1.11.2 0003676,0008408 Q91XB0 37870446 301 TLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASSSRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGT 8hcc D 2.0 BS01 AMP D 1 E20 A21 G23 A81 I84 Y129 E16 A17 G19 A77 I80 Y125 3.1.11.2 0003676,0008408 Q91XB0 37870446 301 TLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASSSRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYG 8hlk A 2.7 BS02 AMP A 1 T623 G738 D739 K740 N756 Y757 P759 T760 D848 F860 K953 T573 G685 D686 K687 N703 Y704 P706 T707 D795 F807 K900 ? 0003824 O54504 38340732 1202 SIYPLSPMQEGMLFHSLYTPDSGIYCSQTLITLEGEINLTVFRQAWEKVVERHSVLRTLFLWIVRKKVDLPWDYQDWRNLLLQTERQQGFEFKVAPLMRCLMIQLSDQTYKFLCNHHHIILDGWSMPIIYQEVLGFYEAGIQGKSHHLPSPRPYQDYIVWLQEQNPSVAESYWQRTLEGFMTPTPLRVDRLQPTYKEYNCHLSASLSKDLQSLAQKHNLTLSTLVQAAWAILLSRYSGESEVLFGVTVSGRPHDLSGVERRVGLFINTLPLRVSIRESDLLLSWLQELQQKQAEIQDYAYVSLAEIQRLSDIPPGVPLFESLVVFENYSLRVKDVENFEETNYPLTVVAIPRQELLIQLIYDTSRFTQDTIERMAGHLQTILTGIVTDPRQRVTQLPILTTQEQHQLLVEWNNTEADYPLDKSLHQLFEEQAAQNPQGIAVIFEDQKLTYQQLNNRGNQLAHCLRDKGVGPESLVGIFMERSLEMVIGLLGILKAGGAYVPLDPDYPTERLGDILSDSGVSLVLTQESLGDFLPQTGAESLCLDRDWEKIATYSPENHFNLTTPENLAYVIYTSGKPKGVLISHRGLMNLICWHQDAFEITPLDKITQLARIAFDAAVWELWPCLTAGASLVLVKPEIMQSPPDLRDWLIAQEITVSFLPTPLVEKILSLEWDENIALRIILTGGDKLHHYPSGLMPFKLINNYGPTENSVVTTSGLVRDYEEGNPPSPSIGKPVYNTKIYILDQNLQPLPIGVPGELHISSVGLARGYLNRLELTQEKFISNPFNSGILYKTGDLVRYLPEGNIEFLGRIDNQVKLRGLRIELGEIEAVLETHSEVEKAVVILREDTSDNQRLVAYIVRKSPSLGIGELRRFLQQQLPAYMVPSAFVILSDFPLNNNGKIDRKKLPVPD 8hu6 D 2.33 BS02 AMP D 1 H420 S422 F487 Y494 R503 S542 Y544 P575 L577 V627 D628 H172 S174 F239 Y246 R255 S294 Y296 P327 L329 V379 D380 3.5.4.6 0003876,0009168,0019239,0032264 Q01433 36563792 902 EFQRVTISGEEKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRRCSEVELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETLCQELALITQAVQSEMLETIPEE 8i51 A 2.76 BS01 AMP A 1 G296 A298 Y318 M320 S321 D411 R426 G291 A293 Y313 M315 S316 D406 R421 ? Q00IB3 602 NDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i51 B 2.76 BS01 AMP B 1 G296 A298 Y318 M320 S321 D411 R426 G291 A293 Y313 M315 S316 D406 R421 ? Q00IB3 602 NDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i51 C 2.76 BS01 AMP C 1 G296 A298 Y318 M320 S321 D411 R426 G291 A293 Y313 M315 S316 D406 R421 ? Q00IB3 602 NDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i51 D 2.76 BS01 AMP D 1 G296 A298 Y318 M320 S321 D411 R426 G291 A293 Y313 M315 S316 D406 R421 ? Q00IB3 602 NDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i51 E 2.76 BS01 AMP E 1 G296 A298 Y318 M320 S321 D411 R426 G291 A293 Y313 M315 S316 D406 R421 ? Q00IB3 602 NDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i51 F 2.76 BS01 AMP F 1 G296 A298 Y318 M320 S321 D411 R426 G291 A293 Y313 M315 S316 D406 R421 ? Q00IB3 602 NDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i6m A 2.59 BS01 AMP A 1 G296 A298 G317 Y318 G319 M320 S321 D411 R426 G291 A293 G312 Y313 G314 M315 S316 D406 R421 ? Q00IB3 1002 NDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i6m B 2.59 BS01 AMP B 1 G296 A298 G317 Y318 G319 M320 S321 D411 R426 G291 A293 G312 Y313 G314 M315 S316 D406 R421 ? Q00IB3 1002 NDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i6m C 2.59 BS01 AMP C 1 G296 A298 G317 Y318 G319 M320 S321 D411 R426 G291 A293 G312 Y313 G314 M315 S316 D406 R421 ? Q00IB3 1002 NDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i6m D 2.59 BS01 AMP D 1 G296 A298 G317 Y318 G319 M320 S321 D411 R426 G291 A293 G312 Y313 G314 M315 S316 D406 R421 ? Q00IB3 1002 NDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i6m E 2.59 BS01 AMP E 1 G296 A298 G317 Y318 G319 M320 S321 D411 R426 G291 A293 G312 Y313 G314 M315 S316 D406 R421 ? Q00IB3 1002 NDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i6m F 2.59 BS01 AMP F 1 G296 A298 G317 Y318 G319 M320 S321 D411 R426 G291 A293 G312 Y313 G314 M315 S316 D406 R421 ? Q00IB3 1002 NDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i8d A 2.51 BS02 AMP A 1 G295 G296 A298 G317 Y318 G319 M320 S321 D411 K432 G292 G293 A295 G314 Y315 G316 M317 S318 D408 K429 ? Q00IB3 602 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLH 8i8d B 2.51 BS02 AMP B 1 G295 G296 A298 G317 Y318 G319 M320 S321 D411 K432 G292 G293 A295 G314 Y315 G316 M317 S318 D408 K429 ? Q00IB3 602 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLH 8i8d C 2.51 BS02 AMP C 1 G295 G296 A298 G317 Y318 G319 M320 S321 D411 K432 G292 G293 A295 G314 Y315 G316 M317 S318 D408 K429 ? Q00IB3 602 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLH 8i8d D 2.51 BS02 AMP D 1 G295 G296 A298 G317 Y318 G319 M320 S321 D411 K432 G292 G293 A295 G314 Y315 G316 M317 S318 D408 K429 ? Q00IB3 602 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLH 8i8d E 2.51 BS02 AMP E 1 G295 G296 A298 G317 Y318 G319 M320 S321 D411 K432 G292 G293 A295 G314 Y315 G316 M317 S318 D408 K429 ? Q00IB3 602 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLH 8i8d F 2.51 BS02 AMP F 1 G295 G296 A298 G317 Y318 G319 M320 S321 D411 K432 G292 G293 A295 G314 Y315 G316 M317 S318 D408 K429 ? Q00IB3 602 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLH 8i8e A 2.63 BS01 AMP A 1 G295 G296 A297 A298 G317 Y318 M320 S321 D411 R426 G292 G293 A294 A295 G314 Y315 M317 S318 D408 R423 ? Q00IB3 701 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i8e B 2.63 BS01 AMP B 1 G295 G296 A297 A298 G317 Y318 M320 S321 D411 R426 G292 G293 A294 A295 G314 Y315 M317 S318 D408 R423 ? Q00IB3 701 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i8e C 2.63 BS01 AMP C 1 G295 G296 A297 A298 G317 Y318 M320 S321 D411 R426 G292 G293 A294 A295 G314 Y315 M317 S318 D408 R423 ? Q00IB3 701 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i8e D 2.63 BS01 AMP D 1 G295 G296 A297 A298 G317 Y318 M320 S321 D411 R426 G292 G293 A294 A295 G314 Y315 M317 S318 D408 R423 ? Q00IB3 701 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i8e E 2.63 BS01 AMP E 1 G295 G296 A297 A298 G317 Y318 M320 S321 D411 R426 G292 G293 A294 A295 G314 Y315 M317 S318 D408 R423 ? Q00IB3 701 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8i8e F 2.63 BS02 AMP F 1 G295 G296 A297 A298 G317 Y318 M320 S321 D411 R426 G292 G293 A294 A295 G314 Y315 M317 S318 D408 R423 ? Q00IB3 701 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8izj A 1.6 BS01 AMP A 1 F28 R29 L128 A130 T131 L158 F27 R28 L127 A129 T130 L157 2.4.2.7 0000287,0003999,0005737,0005829,0006166,0006168,0009116,0016757,0042803,0044209 P69503 201 TATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH 8izj B 1.6 BS01 AMP B 1 F28 R29 L128 A130 T131 G132 T134 F28 R29 L128 A130 T131 G132 T134 2.4.2.7 0000287,0003999,0005737,0005829,0006166,0006168,0009116,0016757,0042803,0044209 P69503 201 MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH 8jbi A 2.356 BS01 AMP A 1 G239 S240 Y243 V254 K313 Y314 I315 G29 S30 Y33 V44 K95 Y96 I97 2.7.-.- D0ZIB5 401 QPAAIEAFINSPEFQKNIRMRDIEKNKIGSGSYGTVYRLHDDFVVKIPVNEGIEHRNSHPDRVSKYLNMANDDKNFSRSAIMNINGKDVTVLVSKYIQGQEFDVEDEDNYRMAEALLKSRGVYMHDINILGNILVKEGVLFFVDGDQIVLSQE 8jbi B 2.356 BS01 AMP B 1 G239 S240 V254 K313 Y314 I315 G29 S30 V43 K92 Y93 I94 2.7.-.- D0ZIB5 401 QPAAIEAFINSPEFQKNIRMRDIEKNKIGSGSGTVYRLHDDFVVKIPVNEGIRNSHPDRVSKYLNMANDDKNFSRSAIMNINGKDVTVLVSKYIQGQEFDVEDEDNYRMAEALLKSRGVYMHDINLGNILVKEGVLFFVDGDQIVLSQE 8jbi C 2.356 BS01 AMP C 1 G239 S240 Y243 V254 K313 Y314 I315 G29 S30 Y33 V44 K99 Y100 I101 2.7.-.- D0ZIB5 401 QPAAIEAFINSPEFQKNIRMRDIEKNKIGSGSYGTVYRLHDDFVVKIPVNERGIKSPEHRNSHPDRVSKYLNMANDDKNFSRSAIMNINGKDVTVLVSKYIQGQEFDVEDEDNYRMAEALLKSRGVYMHDINILGNILVKEGVLFFVDGDQIVLSQE 8jbi D 2.356 BS01 AMP D 1 G239 Y243 V246 K313 Y314 I315 G28 Y32 V35 K95 Y96 I97 2.7.-.- D0ZIB5 401 PAAIEAFINSPEFQKNIRMRDIEKNKIGSGSYGTVYRLHDDFVVKIPVNERGIKSPENSHPDVSKYLNMANDDKNFSRSAIMNINGKDVTVLVSKYIQGQEFDVEDEDNYRMAEALLKSRGVYMHDINILGNILVKEGVLFFVDGDQIVLSQE 8jbi D 2.356 BS02 AMP A 1 N350 L352 V361 N132 L134 V143 2.7.-.- D0ZIB5 401 PAAIEAFINSPEFQKNIRMRDIEKNKIGSGSYGTVYRLHDDFVVKIPVNERGIKSPENSHPDVSKYLNMANDDKNFSRSAIMNINGKDVTVLVSKYIQGQEFDVEDEDNYRMAEALLKSRGVYMHDINILGNILVKEGVLFFVDGDQIVLSQE 8jgl A 3.14 BS01 AMP A 1 L667 A668 Y689 G691 R781 I794 T796 D799 L567 A568 Y589 G591 R660 I673 T675 D678 P51791 39107281 901 GVGTYDDFHTIDWVREKCKDRERHRRINSKKKESAWEMTKSLYDAWSGWLVVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESSSLCDYRIPDRPAGVGVYSAIWQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREGIYEAHIRLNGYPFLDAKEEFTHTTLAADVMRPRRSDPPLAVLTQDNMTVDDIENMINETSYNGFPVIMSKESQRLVGFALRRDLTIAIESARKKVCFAQLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDILRHMA 8jgl B 3.14 BS01 AMP B 1 L667 A668 Y689 N690 G691 I794 T796 D799 L567 A568 Y589 N590 G591 I673 T675 D678 P51791 39107281 901 GVGTYDDFHTIDWVREKCKDRERHRRINSKKKESAWEMTKSLYDAWSGWLVVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESSSLCDYRIPDRPAGVGVYSAIWQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREGIYEAHIRLNGYPFLDAKEEFTHTTLAADVMRPRRSDPPLAVLTQDNMTVDDIENMINETSYNGFPVIMSKESQRLVGFALRRDLTIAIESARKKVCFAQLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDILRHMA 8jka A 2.25 BS03 AMP A 1 N88 H91 H117 T118 D135 T168 L172 P178 Y180 T183 N87 H90 H116 T117 D134 T167 L171 P177 Y179 T182 3.6.1.41 0000166,0005515,0046872 A0A0H2URF8 38701795 404 SYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRFGVDVEKASLAGLLHDYAKKLSDQEFLVLIDRYQLDPDLKNWGNNVWHGMVGIYKIQEDLDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKAVAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLK 8jo3 A 2.66 BS01 AMP A 1 L158 V161 R183 G244 T245 Y281 Y286 H287 L156 V159 R181 G242 T243 Y279 Y284 H285 ? A0A2H5FI52 38776962 501 YTKIESSLLLALDYPKLDESDFILLLTKFLEKKLGNNDNYPTFSKQIQKYYLEQEYKKAIENILRLCQENETLLGTNLVQRLITKSSQVTSNPKDNESRRFYEVLYAEHLESILRKDFDCSIFDELNEAYNEVRPEYTVNDLTKINTFEEARKLILAFVMLNDNVELGLKAQSAIYQKKDRSREELGQVLTANPGIMKPNSPNFADNTVPIKKIDKIAIDEKKAGGYSKTNPQVPFVASLSGTTYSLVVVLQKYMDKHKTDPNLEKKINNIVMLWTSAYIKDGYHSYKEVIDIFKDAHIQSIFARANIKLDYAIIDDTDHEFHRAQEYTQGIATKAMMHQELVQKVQEKS 8jyu A 2.19 BS01 AMP A 1 H226 G296 A297 A298 G317 Y318 G319 M320 S321 D411 R426 H223 G293 A294 A295 G314 Y315 G316 M317 S318 D408 R423 Q00IB3 602 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8jyu B 2.19 BS01 AMP B 1 H226 G296 A297 A298 G317 Y318 G319 M320 S321 D411 R426 H223 G293 A294 A295 G314 Y315 G316 M317 S318 D408 R423 Q00IB3 602 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8jyu C 2.19 BS01 AMP C 1 H226 G296 A297 A298 G317 Y318 G319 M320 S321 D411 R426 H223 G293 A294 A295 G314 Y315 G316 M317 S318 D408 R423 Q00IB3 602 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8jyu D 2.19 BS01 AMP D 1 H226 G296 A297 A298 G317 Y318 G319 M320 S321 D411 R426 H223 G293 A294 A295 G314 Y315 G316 M317 S318 D408 R423 Q00IB3 602 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8jyu E 2.19 BS01 AMP E 1 H226 G296 A297 A298 G317 Y318 G319 M320 S321 D411 R426 H223 G293 A294 A295 G314 Y315 G316 M317 S318 D408 R423 Q00IB3 602 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8jyu F 2.19 BS01 AMP F 1 H226 G296 A297 A298 G317 Y318 G319 M320 S321 D411 R426 H223 G293 A294 A295 G314 Y315 G316 M317 S318 D408 R423 Q00IB3 602 YVNDPSNYQLLIKNLLFSPVAFNPEQEIVYANHRRHSYKTFHDRVRQFANALTKMGVKKGDTVAVMDYDSHRYLECYFAIPMIGAKLHMINVRLSPEQILYTIDHAEDDIILIHEEFLPILDQIKGRIDTVTRYVVLRDDEECEYERLLEQESTEYNFPDFDENTVATTFYTTGTTGFPKGVFFTHRQLVLHTMGILSTIGTNASQGRLHQGDIYMPITPMFHVHAWGLPYMATMLGVKQVYPGKYVPDVLLNLIEQEKVTFSHCVPTILHLLLSSPKSKAMDFSGWKVVIGGAALPKALCKSALERDIDVFAGYGMSETGPILSIVQLTPEQLELDVDQQAEYRSKTGKKVALVEAYIVDEDMNKLPHDGETAGEIVVRAPWLTPNYYKDNKNSKALWRGGYLHTGDVAHIDDEGFIKITDRVKDMIKISGEWVSSLELEDILHQHQSVSEVAVIGMPHNKWGEVPLALVTLKEDAQVTEKELLGFAKDFINKGILAREALLLKVKIVDEIAKTSVGKVDKKELRKLHL 8ofg A 2.4 BS01 AMP A 1 L111 D151 G152 Y167 L168 T182 R183 A186 L25 D65 G66 Y81 L82 T96 R97 A100 2.7.7.85 0004016,0006171 Q8DP14 301 SAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLDAKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIGLSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKE 8oif A 3.5 BS01 AMP I 1 V438 G439 G441 M469 L516 L539 D540 V364 G365 G367 M395 L442 L465 D466 6.2.1.- 0004842,0005515,0005524,0005634,0005654,0005737,0005829,0006974,0008641,0016567,0016874,0019782,0019941,0032020,0032446,0036211,0045087 P41226 38042859 201 ARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSPGILTLRKHYFRDGDLVTFLNDCDPRSIEIGTFSRYLAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLHGRPPQPWDPVDAETVVGLARLDEALVRTVALSSAGVLSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHTLQWARIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFAPAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGFPPLHYEL 8oto A 1.8 BS01 AMP A 1 D6897 L6898 D6912 C6913 M6929 Y6930 D99 L100 D114 C115 M131 Y132 2.1.1.56,2.1.1.57,2.7.7.48,2.7.7.50,3.1.13.-,3.4.19.12,3.4.22.-,3.4.22.69,3.6.4.12,3.6.4.13,4.6.1.- 0004483 P0DTD1 7212 SSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVNNENL 8qjn B 1.65 BS04 AMP B 1 Y89 N91 H151 K158 G159 N161 H175 Y63 N65 H125 K132 G133 N135 H149 406 WGAQGHRLVAEVADARLNPTARAEVDRLLATEPDATLASIAPWADQLRAKDPGLGRRSAGWHYVNIAEDNCHYEAPKHCRNGNCIVEALKAQSTILGDRSLTDGERLQALKFVVHLVGDIHQPMHAGYAHDKGGNDFQLQFGNRGTNLHSLWDSGMLNTRKLDDAGYLPLLQSQRAPKLARQSNPQRDPQTWAEASCRISMQAGVYPATRKIGDEYTERYRPLAEAQLRLAGENLAQLLNRVLG 8rj6 A 1.9 BS03 AMP A 1 T31 G32 L35 R36 M53 K57 V59 V64 G85 R88 Q92 R156 R167 T31 G32 L35 R36 M53 K57 V59 V64 G85 R88 Q92 R156 R167 0000287,0004017,0004550,0005515,0005524,0005737,0005829,0006172,0009123,0009132,0009165,0015951,0016208,0016301,0016310,0044209,0046940,0050145 P69441 39121211 303 MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG 8rj6 B 1.9 BS02 AMP B 1 T31 G32 L35 R36 M53 V59 V64 R88 Q92 T31 G32 L35 R36 M53 V59 V64 R88 Q92 0000287,0004017,0004550,0005515,0005524,0005737,0005829,0006172,0009123,0009132,0009165,0015951,0016208,0016301,0016310,0044209,0046940,0050145 P69441 39121211 302 MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG 8se9 A 3.2 BS01 AMP B 1 G441 D468 D470 L516 A538 L539 D540 G418 D445 D447 L493 A515 L516 D517 6.2.1.- 0004842,0005515,0005524,0005634,0005654,0005737,0005829,0006974,0008641,0016567,0016874,0019782,0019941,0032020,0032446,0036211,0045087 P41226 37553340 1101 SPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLELASASAEFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFAPAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTAFPPLHYEL 8sea A 3.4 BS01 AMP B 1 G441 A442 D468 M469 K492 L516 L539 D540 G421 A422 D448 M449 K472 L496 L519 D520 6.2.1.- 0004842,0005515,0005524,0005634,0005654,0005737,0005829,0006974,0008641,0016567,0016874,0019782,0019941,0032020,0032446,0036211,0045087 P41226 37553340 1101 VLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLELASASAEFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFAPAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTAFPPLHYEL 8seb A 3.24 BS01 AMP B 1 V438 G439 G441 D468 M469 D470 L516 L539 D540 V415 G416 G418 D445 M446 D447 L493 L516 D517 6.2.1.- 0004842,0005515,0005524,0005634,0005654,0005737,0005829,0006974,0008641,0016567,0016874,0019782,0019941,0032020,0032446,0036211,0045087 P41226 37553340 201 SPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLELASASAEFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFAPAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTAFPPLHYEL 8seq A 3.4 BS01 AMP A 1 K4214 M4954 C4958 F4959 T4979 H4983 N4984 L4985 K3900 M4293 C4297 F4298 T4318 H4322 N4323 L4324 ? 0003151,0005216,0005219,0005245,0005262,0005509,0005515,0005516,0005524,0005790,0006811,0006816,0006874,0006936,0006941,0008144,0014802,0014808,0015278,0015643,0016020,0016529,0019722,0030018,0031090,0033017,0034704,0035381,0042383,0042802,0043588,0043931,0044325,0046872,0048741,0051209,0051289,0055085,0070588,0071277,0071313,0097718,1990425 P11716 37192614 5101 VQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLEQSLSVRALQEMLANHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSCCEEGYVTGGHVLRLFHGHMDECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALTEDQGLVVVDACKAHTKATSFCFRVSKEKLPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLKKKAILHQEGHMDDALFLTRCQQEESQAARMIHSTAGLYNQFIKGLDSFSGKPRGSGPPAGPALPIEAVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEYAGEEAAESWKEIVNLLYELLASLIRGNRANCALFSTNLDWVVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLRLEPIKEYRREGPRGPHLVGPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVENQSRWDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPPEHPHYEVARMDGTVDTPPCLRLAHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTDNRDDPEIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQDPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRKGGNARRHGLPGVGVTTSLRPPHHFSPPCFVAALPAAGVAEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEELEEGLLQMKLPESVKLQMCNLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYALLMRAFTMSAAETARRTREFRSPPQEQINMLLHFKDEADEEDCPLPEDIRQDLQDFHQDLLAHCGIQLEKKPQSLQELVSHMVVRWAQEDYVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGETKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGVPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRMAMPCLCAIAGALPPDYVDASYSSKAEKNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGEYNPQPPDLSGVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRLDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTKNTYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLDRLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEATWMKRLAVFAQPIVSRARPELLHSHFIPTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAHWLTEPNANAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADSKSKMARRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIMLAKTRYALKDTDEEVREFLQNNLHLQGKVEGSPSLRWQMALYRGLPGREEDADDPEKIVRRVQEVSAVLYHLEQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEVEVSFEEKEMEKQRLLYQQSRLHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINFEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPNMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS 8seq B 3.4 BS01 AMP B 1 K4214 M4954 C4958 F4959 T4979 H4983 N4984 L4985 K3900 M4293 C4297 F4298 T4318 H4322 N4323 L4324 ? 0003151,0005216,0005219,0005245,0005262,0005509,0005515,0005516,0005524,0005790,0006811,0006816,0006874,0006936,0006941,0008144,0014802,0014808,0015278,0015643,0016020,0016529,0019722,0030018,0031090,0033017,0034704,0035381,0042383,0042802,0043588,0043931,0044325,0046872,0048741,0051209,0051289,0055085,0070588,0071277,0071313,0097718,1990425 P11716 37192614 5101 VQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLEQSLSVRALQEMLANHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSCCEEGYVTGGHVLRLFHGHMDECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALTEDQGLVVVDACKAHTKATSFCFRVSKEKLPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLKKKAILHQEGHMDDALFLTRCQQEESQAARMIHSTAGLYNQFIKGLDSFSGKPRGSGPPAGPALPIEAVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEYAGEEAAESWKEIVNLLYELLASLIRGNRANCALFSTNLDWVVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLRLEPIKEYRREGPRGPHLVGPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVENQSRWDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPPEHPHYEVARMDGTVDTPPCLRLAHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTDNRDDPEIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQDPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRKGGNARRHGLPGVGVTTSLRPPHHFSPPCFVAALPAAGVAEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEELEEGLLQMKLPESVKLQMCNLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYALLMRAFTMSAAETARRTREFRSPPQEQINMLLHFKDEADEEDCPLPEDIRQDLQDFHQDLLAHCGIQLEKKPQSLQELVSHMVVRWAQEDYVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGETKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGVPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRMAMPCLCAIAGALPPDYVDASYSSKAEKNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGEYNPQPPDLSGVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRLDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTKNTYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLDRLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEATWMKRLAVFAQPIVSRARPELLHSHFIPTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAHWLTEPNANAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADSKSKMARRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIMLAKTRYALKDTDEEVREFLQNNLHLQGKVEGSPSLRWQMALYRGLPGREEDADDPEKIVRRVQEVSAVLYHLEQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEVEVSFEEKEMEKQRLLYQQSRLHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINFEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPNMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS 8seq C 3.4 BS01 AMP C 1 K4214 M4954 C4958 F4959 T4979 H4983 N4984 L4985 K3900 M4293 C4297 F4298 T4318 H4322 N4323 L4324 ? 0003151,0005216,0005219,0005245,0005262,0005509,0005515,0005516,0005524,0005790,0006811,0006816,0006874,0006936,0006941,0008144,0014802,0014808,0015278,0015643,0016020,0016529,0019722,0030018,0031090,0033017,0034704,0035381,0042383,0042802,0043588,0043931,0044325,0046872,0048741,0051209,0051289,0055085,0070588,0071277,0071313,0097718,1990425 P11716 37192614 5101 VQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLEQSLSVRALQEMLANHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSCCEEGYVTGGHVLRLFHGHMDECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALTEDQGLVVVDACKAHTKATSFCFRVSKEKLPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLKKKAILHQEGHMDDALFLTRCQQEESQAARMIHSTAGLYNQFIKGLDSFSGKPRGSGPPAGPALPIEAVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEYAGEEAAESWKEIVNLLYELLASLIRGNRANCALFSTNLDWVVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLRLEPIKEYRREGPRGPHLVGPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVENQSRWDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPPEHPHYEVARMDGTVDTPPCLRLAHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTDNRDDPEIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQDPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRKGGNARRHGLPGVGVTTSLRPPHHFSPPCFVAALPAAGVAEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEELEEGLLQMKLPESVKLQMCNLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYALLMRAFTMSAAETARRTREFRSPPQEQINMLLHFKDEADEEDCPLPEDIRQDLQDFHQDLLAHCGIQLEKKPQSLQELVSHMVVRWAQEDYVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGETKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGVPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRMAMPCLCAIAGALPPDYVDASYSSKAEKNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGEYNPQPPDLSGVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRLDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTKNTYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLDRLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEATWMKRLAVFAQPIVSRARPELLHSHFIPTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAHWLTEPNANAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADSKSKMARRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIMLAKTRYALKDTDEEVREFLQNNLHLQGKVEGSPSLRWQMALYRGLPGREEDADDPEKIVRRVQEVSAVLYHLEQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEVEVSFEEKEMEKQRLLYQQSRLHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINFEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPNMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS 8seq D 3.4 BS01 AMP D 1 K4214 M4954 C4958 F4959 T4979 H4983 N4984 L4985 K3900 M4293 C4297 F4298 T4318 H4322 N4323 L4324 ? 0003151,0005216,0005219,0005245,0005262,0005509,0005515,0005516,0005524,0005790,0006811,0006816,0006874,0006936,0006941,0008144,0014802,0014808,0015278,0015643,0016020,0016529,0019722,0030018,0031090,0033017,0034704,0035381,0042383,0042802,0043588,0043931,0044325,0046872,0048741,0051209,0051289,0055085,0070588,0071277,0071313,0097718,1990425 P11716 37192614 5101 VQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLEQSLSVRALQEMLANHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSCCEEGYVTGGHVLRLFHGHMDECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALTEDQGLVVVDACKAHTKATSFCFRVSKEKLPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLKKKAILHQEGHMDDALFLTRCQQEESQAARMIHSTAGLYNQFIKGLDSFSGKPRGSGPPAGPALPIEAVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEYAGEEAAESWKEIVNLLYELLASLIRGNRANCALFSTNLDWVVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLRLEPIKEYRREGPRGPHLVGPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVENQSRWDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPPEHPHYEVARMDGTVDTPPCLRLAHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTDNRDDPEIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQDPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRKGGNARRHGLPGVGVTTSLRPPHHFSPPCFVAALPAAGVAEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEELEEGLLQMKLPESVKLQMCNLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYALLMRAFTMSAAETARRTREFRSPPQEQINMLLHFKDEADEEDCPLPEDIRQDLQDFHQDLLAHCGIQLEKKPQSLQELVSHMVVRWAQEDYVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGETKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGVPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRMAMPCLCAIAGALPPDYVDASYSSKAEKNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGEYNPQPPDLSGVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRLDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTKNTYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLDRLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEATWMKRLAVFAQPIVSRARPELLHSHFIPTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAHWLTEPNANAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADSKSKMARRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIMLAKTRYALKDTDEEVREFLQNNLHLQGKVEGSPSLRWQMALYRGLPGREEDADDPEKIVRRVQEVSAVLYHLEQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEVEVSFEEKEMEKQRLLYQQSRLHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINFEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPNMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS 8sex A 2.84 BS01 AMP A 1 M4954 K4957 C4958 F4959 T4979 H4983 N4984 M543 K546 C547 F548 T568 H572 N573 ? 0003151,0005216,0005219,0005245,0005262,0005509,0005515,0005516,0005524,0005790,0006811,0006816,0006874,0006936,0006941,0008144,0014802,0014808,0015278,0015643,0016020,0016529,0019722,0030018,0031090,0033017,0034704,0035381,0042383,0042802,0043588,0043931,0044325,0046872,0048741,0051209,0051289,0055085,0070588,0071277,0071313,0097718,1990425 P11716 37192614 5101 NFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPNMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS 8sex B 2.84 BS01 AMP B 1 M4954 K4957 C4958 F4959 T4979 H4983 N4984 M543 K546 C547 F548 T568 H572 N573 ? 0003151,0005216,0005219,0005245,0005262,0005509,0005515,0005516,0005524,0005790,0006811,0006816,0006874,0006936,0006941,0008144,0014802,0014808,0015278,0015643,0016020,0016529,0019722,0030018,0031090,0033017,0034704,0035381,0042383,0042802,0043588,0043931,0044325,0046872,0048741,0051209,0051289,0055085,0070588,0071277,0071313,0097718,1990425 P11716 37192614 5101 NFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPNMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS 8sex C 2.84 BS01 AMP C 1 M4954 K4957 C4958 F4959 T4979 H4983 N4984 M543 K546 C547 F548 T568 H572 N573 ? 0003151,0005216,0005219,0005245,0005262,0005509,0005515,0005516,0005524,0005790,0006811,0006816,0006874,0006936,0006941,0008144,0014802,0014808,0015278,0015643,0016020,0016529,0019722,0030018,0031090,0033017,0034704,0035381,0042383,0042802,0043588,0043931,0044325,0046872,0048741,0051209,0051289,0055085,0070588,0071277,0071313,0097718,1990425 P11716 37192614 5101 NFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPNMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS 8sex D 2.84 BS01 AMP D 1 M4954 K4957 C4958 F4959 T4979 H4983 N4984 M543 K546 C547 F548 T568 H572 N573 ? 0003151,0005216,0005219,0005245,0005262,0005509,0005515,0005516,0005524,0005790,0006811,0006816,0006874,0006936,0006941,0008144,0014802,0014808,0015278,0015643,0016020,0016529,0019722,0030018,0031090,0033017,0034704,0035381,0042383,0042802,0043588,0043931,0044325,0046872,0048741,0051209,0051289,0055085,0070588,0071277,0071313,0097718,1990425 P11716 37192614 5101 NFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPNMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS 8sf3 A 1.7 BS01 AMP A 1 G439 E440 P441 T464 W465 Q467 T468 D552 R567 R578 G398 E399 P400 T423 W424 Q426 T427 D511 R526 R537 6.2.1.1 0003987,0005524,0006085,0016208,0016874,0019427 A4I093 801 RDSNVVEPTEANGKKSHVGPHLGSRMRIYEYSIEHNDAFWAEIARRDFYWKTTWPDDQHVKSYNFDKSKGPIFVKWFEGAVTNVCYNALDRHLPAHKDRVCFYFEGNDPSVTEAVTYGSMYTRVVELANVLKYQYGIAKGDRVGLYLPMIPFAAVAMLACARIGAVITVIFGGFSAQALSSRLKDAQTKLLITADASARGTKPIPLKDVADEALKECEEEGMSIACLVAENMSCKMKEGRDTWYGDALARLTPEQHEECPVEWMDAEDVLFLLYTSGSTGKPKAIVHTTAGYMVYASTTFMYSFDYHMDDVYFCTADIGWITGHSYVVYGPMIHCATSVLFEGVPNYPDYSRWWQLVEKYKVSILYTAPTAIRSLMQAGDDYVKVGNRSTLRVLGSVGEPINVEAWKWLRDVGGEGHCDVSDTWWQTETGGHMITPMPGCTPMKPGSATLPFFGVQPVILDPMKLHEKQGPAEGLLAIRAPWPGMARTIYGDHARFEKTYFGVDGYYMTGDGARRDSDGYYWITGRVDDVLNVSGHRIGTSEIEDAVNTHPAVVESAVVGFPHNIKGEGIYVFLTFRQGTEVTPELLAAVKATVRKVIGPLATPDVMQVARVGLPKTRSGKIVRRILRKVSAGQYTELGDTSTLANPDVVEDLIAEHQRLCS 8slf A 2.9 BS01 AMP A 1 R195 F205 F210 Q212 E282 E284 A324 A325 G326 R329 R137 F147 F152 Q154 E221 E223 A263 A264 G265 R268 6.1.1.14 0000166,0004812,0004820,0005524,0005737,0006412,0006418,0006426,0046872 G7CIG9 501 ASIIDTVANLAKRRGFVYQSGEIYGGTRSAWDYGPLGVELKENIKRQWWKSMVTAREDVVGIDTSIILPREVWVASGHVDVFNMMLKTYLGPIESDEGLHYLRPETAQGIFTNFANVVTTARKKPPFGIAQTGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWIDTRLQWYVDLGIDRDNLRLYEHPPEKYAERTVDIEYKYGFAGDPWGELEGIANRTDFDLSTHSKHSGVDLSYYDQATDTRYVPYVIEPAAGLTRSLMAFLIDAYSEDEKRTVLRFDPRLAPVKVAVLPLSRHADLSPKARDLAAELRQHWNVEFDDAGAIGRRYRRQDEVGTPYCVTVDFDSLEDNAVTVRERDSMAQERISIDQVTDYLAVRLKGC 8slf B 2.9 BS01 AMP B 1 R195 F205 T207 F210 E282 L283 E284 A324 G326 R329 R170 F180 T182 F185 E257 L258 E259 A299 G301 R304 6.1.1.14 0000166,0004812,0004820,0005524,0005737,0006412,0006418,0006426,0046872 G7CIG9 501 ASIIDTVANLAKRRGFVYQSGEIYGGTRSAWDYGPLGVELKENIKRQWWKSMVTAREDVVGIDTSIILPREVWVASGHVDVFHDPLVECLNCHRRHRQDHVVCPDCGTWTEPREFNMMLKTYLGPIESDEGLHYLRPETAQGIFTNFANVVTTARKKPPFGIAQTGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWIDTRLQWYVDLGIDRDNLRLYEHPPEKLSHYAERTVDIEYKYGFAGDPWGELEGIANRTDFDLSTHSKHSGVDLSYYDQATDTRYVPYVIEPAAGLTRSLMAFLIDAYSEDEAPNAKGGVDKRTVLRFDPRLAPVKVAVLPLSRHADLSPKARDLAAELRQHWNVEFDDAGAIGRRYRRQDEVGTPYCVTVDFDSLEDNAVTVRERDSMAQERISIDQVTDYLAVRLKGC 8slh A 3.05 BS01 AMP A 1 F205 R206 T207 F210 E282 L283 G326 R329 F116 R117 T118 F121 E193 L194 G237 R240 6.1.1.14 0000166,0004812,0004820,0005524,0005737,0006412,0006418,0006426,0046872 G7CIG9 501 ASIIDTVANLAKRRGFVYQSGEITRSAWDYGPLGVELKENIKRQWWKSMVTAREDVVGIDTSIILPREVWVASGLHRPETAQGIFTNFANVVTTARKKPPFGIAQTGKSFPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWIDTRLQWYVDLGIDRDNLRLYEHPPEKLSHYAERTVDIEYKYGFAGDPWGELEGIANRTDFDLSTHSKHSGVDLSYYDQATDTRYVPYVIEPAAGLTRSLMAFLIDAYSEDVDKRTVLRFDPRLAPVKVAVLPLSRHADLSPKARDLAAELRQHWNVEFDDAGAIGRRYRRQDEVGTPYCVTVDFDSLEDNAVTVRERDSMAQERISIDQVTDYLAVRLK 8sr7 A 1.97 BS02 AMP A 1 W1264 G1321 N1326 F1372 W1145 G1202 N1207 F1253 ? 0005216,0005261,0005262,0005886,0006811,0016020,0055085,0070588,0098655 F2UB89 38773335 1502 SVAAKTLLIENEDGKGSTRMEVQDFMKRFHMHASEDDKTGSPSTAWGTLRFPTKEATAPYLRLSVNDDPEDALLFVKAMLAQKYGETYDRPSLILSVTGGARNFTLPPRLETAIAKGLRLAAQRTNAWVVTGGTNTGVMKLTGQIMEALSKTQSHFIPPTIGIATYGVIIGGDDMTRGEPPKIGLEYEMHKKDPPKTTPLDDNHNLFLLVDDGSTNKFGKEIKFRAAFENAAGQAFAAPVVTIVVQGGPGTLGTALQAVRQGTPIVVVDGSGLAADVLAYAYNFMHNPLTRFKSYTIDDLRQKVAQTFNPKSSQQLTNLLDSALECVQDPNLVVVYSLQESGIDEFDDCILKAIFSSQGKLGNKLKQAMYFDQLDVAKRALSEASKNGQHNEIAACINDNLMAAMMHNKPHFVELYLGFDAKIYELKPSEEVAKTNITALDELPSFALAIEELYKREAKKPHSHVQRLVSLSNTDVLGRHYRGRDLANTRAYNVLRMDQIFARLVSKDFSVNRDFTIYDSKYDKVPGIQFRRTAQASHMLFLWAICLDRFRMARHFWLIGDQSIINALVASRILERLSTHRALQGPHLAEERAKMQHNAKKFEELAVGVLGECHGSDSHMASEMLHSKNDMFNKKNAINIAYDAKSLAFLSHPATQSVINADWYGHLKSVTSFWAVLFAFFFPFFVLPFINFSGAHRLRRKFAKFYSAPYTRFISDLLSHFVLCVVTSYFVLDKLEDTISAIEWILLVWFVALLLEELRQMIFCDGIAEYISDTWNRLDLIMITLFFVGFFTHASDPSNQDSKVVSKGIHAFLVVVLWLRFMRYYALSKNLGPKLIMMMEMMKDVSTFVFLLLIFLIGYGVAAQSLLSPDEDFSSRTFIGVLFRPYFQIYGELFLDDLNSEANCLGDTPFTECSRETVRMVPFFLAVYILGSNVLLVNLLIAMFNDTYMKVQEAAEDLWRKQNYELCAEYKDRPFLPAPFILLAHVHMLFMRLLRLCGVHTQEHEKIQDDETKRKITTFEELNTDKFLRRWERERQEMLEARVKMTNDNVVQAMGMMDQLLEHMISFRFSLDQQATKINRLNSAVAVHGHTAEAAEWYVPPEEYPKSGGVKRYLIDASMVPLSIMCPSYDPVEYTHPSVAAQPVWADPADPRKIKFNVKDEVNGKVVDRTSCHPSGISIDSNTGRPINPWGRTGMTGRGLLGKWGVNQAADTVVTRWKRSPDGSILERDGKKVLEFVAIQRQDNKMWAIPGGFVDNGEDVALTSGREFMEEALGMGTSADLMSAESKDSLAALFSSGTIVARIYCEDPRNTDNAWVETTCVNFHDESGRHAARLKLQGGDDAEHARWMMVHGGLNLFASHRTLLQHVTSALNAYF 8sr7 B 1.97 BS03 AMP B 1 W1264 G1321 N1326 F1372 W1145 G1202 N1207 F1253 ? 0005216,0005261,0005262,0005886,0006811,0016020,0055085,0070588,0098655 F2UB89 38773335 1502 SVAAKTLLIENEDGKGSTRMEVQDFMKRFHMHASEDDKTGSPSTAWGTLRFPTKEATAPYLRLSVNDDPEDALLFVKAMLAQKYGETYDRPSLILSVTGGARNFTLPPRLETAIAKGLRLAAQRTNAWVVTGGTNTGVMKLTGQIMEALSKTQSHFIPPTIGIATYGVIIGGDDMTRGEPPKIGLEYEMHKKDPPKTTPLDDNHNLFLLVDDGSTNKFGKEIKFRAAFENAAGQAFAAPVVTIVVQGGPGTLGTALQAVRQGTPIVVVDGSGLAADVLAYAYNFMHNPLTRFKSYTIDDLRQKVAQTFNPKSSQQLTNLLDSALECVQDPNLVVVYSLQESGIDEFDDCILKAIFSSQGKLGNKLKQAMYFDQLDVAKRALSEASKNGQHNEIAACINDNLMAAMMHNKPHFVELYLGFDAKIYELKPSEEVAKTNITALDELPSFALAIEELYKREAKKPHSHVQRLVSLSNTDVLGRHYRGRDLANTRAYNVLRMDQIFARLVSKDFSVNRDFTIYDSKYDKVPGIQFRRTAQASHMLFLWAICLDRFRMARHFWLIGDQSIINALVASRILERLSTHRALQGPHLAEERAKMQHNAKKFEELAVGVLGECHGSDSHMASEMLHSKNDMFNKKNAINIAYDAKSLAFLSHPATQSVINADWYGHLKSVTSFWAVLFAFFFPFFVLPFINFSGAHRLRRKFAKFYSAPYTRFISDLLSHFVLCVVTSYFVLDKLEDTISAIEWILLVWFVALLLEELRQMIFCDGIAEYISDTWNRLDLIMITLFFVGFFTHASDPSNQDSKVVSKGIHAFLVVVLWLRFMRYYALSKNLGPKLIMMMEMMKDVSTFVFLLLIFLIGYGVAAQSLLSPDEDFSSRTFIGVLFRPYFQIYGELFLDDLNSEANCLGDTPFTECSRETVRMVPFFLAVYILGSNVLLVNLLIAMFNDTYMKVQEAAEDLWRKQNYELCAEYKDRPFLPAPFILLAHVHMLFMRLLRLCGVHTQEHEKIQDDETKRKITTFEELNTDKFLRRWERERQEMLEARVKMTNDNVVQAMGMMDQLLEHMISFRFSLDQQATKINRLNSAVAVHGHTAEAAEWYVPPEEYPKSGGVKRYLIDASMVPLSIMCPSYDPVEYTHPSVAAQPVWADPADPRKIKFNVKDEVNGKVVDRTSCHPSGISIDSNTGRPINPWGRTGMTGRGLLGKWGVNQAADTVVTRWKRSPDGSILERDGKKVLEFVAIQRQDNKMWAIPGGFVDNGEDVALTSGREFMEEALGMGTSADLMSAESKDSLAALFSSGTIVARIYCEDPRNTDNAWVETTCVNFHDESGRHAARLKLQGGDDAEHARWMMVHGGLNLFASHRTLLQHVTSALNAYF 8sr7 C 1.97 BS03 AMP C 1 W1264 G1321 N1326 F1372 W1145 G1202 N1207 F1253 ? 0005216,0005261,0005262,0005886,0006811,0016020,0055085,0070588,0098655 F2UB89 38773335 1502 SVAAKTLLIENEDGKGSTRMEVQDFMKRFHMHASEDDKTGSPSTAWGTLRFPTKEATAPYLRLSVNDDPEDALLFVKAMLAQKYGETYDRPSLILSVTGGARNFTLPPRLETAIAKGLRLAAQRTNAWVVTGGTNTGVMKLTGQIMEALSKTQSHFIPPTIGIATYGVIIGGDDMTRGEPPKIGLEYEMHKKDPPKTTPLDDNHNLFLLVDDGSTNKFGKEIKFRAAFENAAGQAFAAPVVTIVVQGGPGTLGTALQAVRQGTPIVVVDGSGLAADVLAYAYNFMHNPLTRFKSYTIDDLRQKVAQTFNPKSSQQLTNLLDSALECVQDPNLVVVYSLQESGIDEFDDCILKAIFSSQGKLGNKLKQAMYFDQLDVAKRALSEASKNGQHNEIAACINDNLMAAMMHNKPHFVELYLGFDAKIYELKPSEEVAKTNITALDELPSFALAIEELYKREAKKPHSHVQRLVSLSNTDVLGRHYRGRDLANTRAYNVLRMDQIFARLVSKDFSVNRDFTIYDSKYDKVPGIQFRRTAQASHMLFLWAICLDRFRMARHFWLIGDQSIINALVASRILERLSTHRALQGPHLAEERAKMQHNAKKFEELAVGVLGECHGSDSHMASEMLHSKNDMFNKKNAINIAYDAKSLAFLSHPATQSVINADWYGHLKSVTSFWAVLFAFFFPFFVLPFINFSGAHRLRRKFAKFYSAPYTRFISDLLSHFVLCVVTSYFVLDKLEDTISAIEWILLVWFVALLLEELRQMIFCDGIAEYISDTWNRLDLIMITLFFVGFFTHASDPSNQDSKVVSKGIHAFLVVVLWLRFMRYYALSKNLGPKLIMMMEMMKDVSTFVFLLLIFLIGYGVAAQSLLSPDEDFSSRTFIGVLFRPYFQIYGELFLDDLNSEANCLGDTPFTECSRETVRMVPFFLAVYILGSNVLLVNLLIAMFNDTYMKVQEAAEDLWRKQNYELCAEYKDRPFLPAPFILLAHVHMLFMRLLRLCGVHTQEHEKIQDDETKRKITTFEELNTDKFLRRWERERQEMLEARVKMTNDNVVQAMGMMDQLLEHMISFRFSLDQQATKINRLNSAVAVHGHTAEAAEWYVPPEEYPKSGGVKRYLIDASMVPLSIMCPSYDPVEYTHPSVAAQPVWADPADPRKIKFNVKDEVNGKVVDRTSCHPSGISIDSNTGRPINPWGRTGMTGRGLLGKWGVNQAADTVVTRWKRSPDGSILERDGKKVLEFVAIQRQDNKMWAIPGGFVDNGEDVALTSGREFMEEALGMGTSADLMSAESKDSLAALFSSGTIVARIYCEDPRNTDNAWVETTCVNFHDESGRHAARLKLQGGDDAEHARWMMVHGGLNLFASHRTLLQHVTSALNAYF 8sr7 D 1.97 BS05 AMP D 1 W1264 G1321 N1326 F1372 W1145 G1202 N1207 F1253 ? 0005216,0005261,0005262,0005886,0006811,0016020,0055085,0070588,0098655 F2UB89 38773335 6004 SVAAKTLLIENEDGKGSTRMEVQDFMKRFHMHASEDDKTGSPSTAWGTLRFPTKEATAPYLRLSVNDDPEDALLFVKAMLAQKYGETYDRPSLILSVTGGARNFTLPPRLETAIAKGLRLAAQRTNAWVVTGGTNTGVMKLTGQIMEALSKTQSHFIPPTIGIATYGVIIGGDDMTRGEPPKIGLEYEMHKKDPPKTTPLDDNHNLFLLVDDGSTNKFGKEIKFRAAFENAAGQAFAAPVVTIVVQGGPGTLGTALQAVRQGTPIVVVDGSGLAADVLAYAYNFMHNPLTRFKSYTIDDLRQKVAQTFNPKSSQQLTNLLDSALECVQDPNLVVVYSLQESGIDEFDDCILKAIFSSQGKLGNKLKQAMYFDQLDVAKRALSEASKNGQHNEIAACINDNLMAAMMHNKPHFVELYLGFDAKIYELKPSEEVAKTNITALDELPSFALAIEELYKREAKKPHSHVQRLVSLSNTDVLGRHYRGRDLANTRAYNVLRMDQIFARLVSKDFSVNRDFTIYDSKYDKVPGIQFRRTAQASHMLFLWAICLDRFRMARHFWLIGDQSIINALVASRILERLSTHRALQGPHLAEERAKMQHNAKKFEELAVGVLGECHGSDSHMASEMLHSKNDMFNKKNAINIAYDAKSLAFLSHPATQSVINADWYGHLKSVTSFWAVLFAFFFPFFVLPFINFSGAHRLRRKFAKFYSAPYTRFISDLLSHFVLCVVTSYFVLDKLEDTISAIEWILLVWFVALLLEELRQMIFCDGIAEYISDTWNRLDLIMITLFFVGFFTHASDPSNQDSKVVSKGIHAFLVVVLWLRFMRYYALSKNLGPKLIMMMEMMKDVSTFVFLLLIFLIGYGVAAQSLLSPDEDFSSRTFIGVLFRPYFQIYGELFLDDLNSEANCLGDTPFTECSRETVRMVPFFLAVYILGSNVLLVNLLIAMFNDTYMKVQEAAEDLWRKQNYELCAEYKDRPFLPAPFILLAHVHMLFMRLLRLCGVHTQEHEKIQDDETKRKITTFEELNTDKFLRRWERERQEMLEARVKMTNDNVVQAMGMMDQLLEHMISFRFSLDQQATKINRLNSAVAVHGHTAEAAEWYVPPEEYPKSGGVKRYLIDASMVPLSIMCPSYDPVEYTHPSVAAQPVWADPADPRKIKFNVKDEVNGKVVDRTSCHPSGISIDSNTGRPINPWGRTGMTGRGLLGKWGVNQAADTVVTRWKRSPDGSILERDGKKVLEFVAIQRQDNKMWAIPGGFVDNGEDVALTSGREFMEEALGMGTSADLMSAESKDSLAALFSSGTIVARIYCEDPRNTDNAWVETTCVNFHDESGRHAARLKLQGGDDAEHARWMMVHGGLNLFASHRTLLQHVTSALNAYF 8srf A 2.52 BS02 AMP A 1 W1264 G1321 N1326 F1372 E1386 D1460 W1147 G1204 N1209 F1255 E1269 D1343 ? 0005216,0005261,0005262,0005886,0006811,0016020,0055085,0070588,0098655 F2UB89 1502 SVAAKTLLIENEDGKGSTRMEVQDFMKRFHMHASEDDKTGSPSTAWGTLRFPTKEATAPYLRLSVNDDPEDALLFVKAMLAQKYGETYDRPSLILSVTGGARNFTLPPRLETAIAKGLRLAAQRTNAWVVTGGTNTGVMKLTGQIMEALSKTQSHFIPPTIGIATYGVIIGGDDMTRGEPPKIGLEYEMHKKDPPKTTPLDDNHNLFLLVDDGSTNKFGKEIKFRAAFENAAGQAFAAPVVTIVVQGGPGTLGTALQAVRQGTPIVVVDGSGLAADVLAYAYNFMHNPLTRFKSYTIDDLRQKVAQTFNPKSSQQLTNLLDSALECVQDPNLVVVYSLQESGIDEFDDCILKAIFSSQGKLGNKLKQAMYFDQLDVAKRALSEASKNGQHNEIAACINDNLMAAMMHNKPHFVELYLGFDAKIYELKPSEEVAKTNITALDELPSFALAIEELYKREAKKPHSHVQRLVSLSNTDVLGRHYRGRDLANTRAYNVLRMDQIFARLVSKDFSVNRDFTIYDSKYDKVPGIQFRRTAQASHMLFLWAICLDRFRMARHFWLIGDQSIINALVASRILERLSTHRALQGPHLAEERAKMQHNAKKFEELAVGVLGECHGSDSHMASEMLHSKNDMFNKKNAINIAYDAKSLAFLSHPATQSVINADWYGHLKSVTSFWAVLFAFFFPFFVLPFINFSGAHRLRRKFAKFYSAPYTRFISDLLSHFVLCVVTSYFVLDKLEDTISAIEWILLVWFVALLLEELRQMIFCDGIAEYISDTWNRLDLIMITLFFVGFFTHASDPSNQDSKVVSKGIHAFLVVVLWLRFMRYYALSKNLGPKLIMMMEMMKDVSTFVFLLLIFLIGYGVAAQSLLSPDEDFSSRTFIGVLFRPYFQIYGELFLDDLNSEANCLGDTPFTECSRETVRMVPFFLAVYILGSNVLLVNLLIAMFNDTYMKVQEAAEDLWRKQNYELCAEYKDRPFLPAPFILLAHVHMLFMRLLRLCGVHTQEHEKIQDDETKRKITTFEELNTDKFLRRWERERQEMLEARVKMTNDNVVQAMGMMDQLLEHMISFRFSLDQQATKIPINRLNSAVAVHGHTAEAAEWYVPPEEYPKSGGVKRYLIDASMVPLSIMCPSYDPVEYTHPSVAAQPVWADPADPRKIKFNVKDEVNGKVVDRTSCHPSGISIDSNTGRPINPWGRTGMTGRGLLGKWGVNQAADTVVTRWKRSPDGSILERDGKKVLEFVAIQRQDNKMWAIPGGFVDNGEDVALTSGREFMEEALGMGTSADLMSAESKDSLAALFSSGTIVARIYCEDPRNTDNAWVETTCVNFHDESGRHAARLKLQGGDDAEHARWMMVHGGLNLFASHRTLLQHVTSALNAYF 8srf B 2.52 BS03 AMP B 1 W1264 G1321 N1326 F1372 E1386 D1460 W1147 G1204 N1209 F1255 E1269 D1343 ? 0005216,0005261,0005262,0005886,0006811,0016020,0055085,0070588,0098655 F2UB89 1502 SVAAKTLLIENEDGKGSTRMEVQDFMKRFHMHASEDDKTGSPSTAWGTLRFPTKEATAPYLRLSVNDDPEDALLFVKAMLAQKYGETYDRPSLILSVTGGARNFTLPPRLETAIAKGLRLAAQRTNAWVVTGGTNTGVMKLTGQIMEALSKTQSHFIPPTIGIATYGVIIGGDDMTRGEPPKIGLEYEMHKKDPPKTTPLDDNHNLFLLVDDGSTNKFGKEIKFRAAFENAAGQAFAAPVVTIVVQGGPGTLGTALQAVRQGTPIVVVDGSGLAADVLAYAYNFMHNPLTRFKSYTIDDLRQKVAQTFNPKSSQQLTNLLDSALECVQDPNLVVVYSLQESGIDEFDDCILKAIFSSQGKLGNKLKQAMYFDQLDVAKRALSEASKNGQHNEIAACINDNLMAAMMHNKPHFVELYLGFDAKIYELKPSEEVAKTNITALDELPSFALAIEELYKREAKKPHSHVQRLVSLSNTDVLGRHYRGRDLANTRAYNVLRMDQIFARLVSKDFSVNRDFTIYDSKYDKVPGIQFRRTAQASHMLFLWAICLDRFRMARHFWLIGDQSIINALVASRILERLSTHRALQGPHLAEERAKMQHNAKKFEELAVGVLGECHGSDSHMASEMLHSKNDMFNKKNAINIAYDAKSLAFLSHPATQSVINADWYGHLKSVTSFWAVLFAFFFPFFVLPFINFSGAHRLRRKFAKFYSAPYTRFISDLLSHFVLCVVTSYFVLDKLEDTISAIEWILLVWFVALLLEELRQMIFCDGIAEYISDTWNRLDLIMITLFFVGFFTHASDPSNQDSKVVSKGIHAFLVVVLWLRFMRYYALSKNLGPKLIMMMEMMKDVSTFVFLLLIFLIGYGVAAQSLLSPDEDFSSRTFIGVLFRPYFQIYGELFLDDLNSEANCLGDTPFTECSRETVRMVPFFLAVYILGSNVLLVNLLIAMFNDTYMKVQEAAEDLWRKQNYELCAEYKDRPFLPAPFILLAHVHMLFMRLLRLCGVHTQEHEKIQDDETKRKITTFEELNTDKFLRRWERERQEMLEARVKMTNDNVVQAMGMMDQLLEHMISFRFSLDQQATKIPINRLNSAVAVHGHTAEAAEWYVPPEEYPKSGGVKRYLIDASMVPLSIMCPSYDPVEYTHPSVAAQPVWADPADPRKIKFNVKDEVNGKVVDRTSCHPSGISIDSNTGRPINPWGRTGMTGRGLLGKWGVNQAADTVVTRWKRSPDGSILERDGKKVLEFVAIQRQDNKMWAIPGGFVDNGEDVALTSGREFMEEALGMGTSADLMSAESKDSLAALFSSGTIVARIYCEDPRNTDNAWVETTCVNFHDESGRHAARLKLQGGDDAEHARWMMVHGGLNLFASHRTLLQHVTSALNAYF 8srf C 2.52 BS03 AMP C 1 W1264 G1321 N1326 F1372 E1386 D1460 W1147 G1204 N1209 F1255 E1269 D1343 ? 0005216,0005261,0005262,0005886,0006811,0016020,0055085,0070588,0098655 F2UB89 1502 SVAAKTLLIENEDGKGSTRMEVQDFMKRFHMHASEDDKTGSPSTAWGTLRFPTKEATAPYLRLSVNDDPEDALLFVKAMLAQKYGETYDRPSLILSVTGGARNFTLPPRLETAIAKGLRLAAQRTNAWVVTGGTNTGVMKLTGQIMEALSKTQSHFIPPTIGIATYGVIIGGDDMTRGEPPKIGLEYEMHKKDPPKTTPLDDNHNLFLLVDDGSTNKFGKEIKFRAAFENAAGQAFAAPVVTIVVQGGPGTLGTALQAVRQGTPIVVVDGSGLAADVLAYAYNFMHNPLTRFKSYTIDDLRQKVAQTFNPKSSQQLTNLLDSALECVQDPNLVVVYSLQESGIDEFDDCILKAIFSSQGKLGNKLKQAMYFDQLDVAKRALSEASKNGQHNEIAACINDNLMAAMMHNKPHFVELYLGFDAKIYELKPSEEVAKTNITALDELPSFALAIEELYKREAKKPHSHVQRLVSLSNTDVLGRHYRGRDLANTRAYNVLRMDQIFARLVSKDFSVNRDFTIYDSKYDKVPGIQFRRTAQASHMLFLWAICLDRFRMARHFWLIGDQSIINALVASRILERLSTHRALQGPHLAEERAKMQHNAKKFEELAVGVLGECHGSDSHMASEMLHSKNDMFNKKNAINIAYDAKSLAFLSHPATQSVINADWYGHLKSVTSFWAVLFAFFFPFFVLPFINFSGAHRLRRKFAKFYSAPYTRFISDLLSHFVLCVVTSYFVLDKLEDTISAIEWILLVWFVALLLEELRQMIFCDGIAEYISDTWNRLDLIMITLFFVGFFTHASDPSNQDSKVVSKGIHAFLVVVLWLRFMRYYALSKNLGPKLIMMMEMMKDVSTFVFLLLIFLIGYGVAAQSLLSPDEDFSSRTFIGVLFRPYFQIYGELFLDDLNSEANCLGDTPFTECSRETVRMVPFFLAVYILGSNVLLVNLLIAMFNDTYMKVQEAAEDLWRKQNYELCAEYKDRPFLPAPFILLAHVHMLFMRLLRLCGVHTQEHEKIQDDETKRKITTFEELNTDKFLRRWERERQEMLEARVKMTNDNVVQAMGMMDQLLEHMISFRFSLDQQATKIPINRLNSAVAVHGHTAEAAEWYVPPEEYPKSGGVKRYLIDASMVPLSIMCPSYDPVEYTHPSVAAQPVWADPADPRKIKFNVKDEVNGKVVDRTSCHPSGISIDSNTGRPINPWGRTGMTGRGLLGKWGVNQAADTVVTRWKRSPDGSILERDGKKVLEFVAIQRQDNKMWAIPGGFVDNGEDVALTSGREFMEEALGMGTSADLMSAESKDSLAALFSSGTIVARIYCEDPRNTDNAWVETTCVNFHDESGRHAARLKLQGGDDAEHARWMMVHGGLNLFASHRTLLQHVTSALNAYF 8srf D 2.52 BS05 AMP D 1 W1264 G1321 N1326 F1372 E1386 D1460 W1147 G1204 N1209 F1255 E1269 D1343 ? 0005216,0005261,0005262,0005886,0006811,0016020,0055085,0070588,0098655 F2UB89 6004 SVAAKTLLIENEDGKGSTRMEVQDFMKRFHMHASEDDKTGSPSTAWGTLRFPTKEATAPYLRLSVNDDPEDALLFVKAMLAQKYGETYDRPSLILSVTGGARNFTLPPRLETAIAKGLRLAAQRTNAWVVTGGTNTGVMKLTGQIMEALSKTQSHFIPPTIGIATYGVIIGGDDMTRGEPPKIGLEYEMHKKDPPKTTPLDDNHNLFLLVDDGSTNKFGKEIKFRAAFENAAGQAFAAPVVTIVVQGGPGTLGTALQAVRQGTPIVVVDGSGLAADVLAYAYNFMHNPLTRFKSYTIDDLRQKVAQTFNPKSSQQLTNLLDSALECVQDPNLVVVYSLQESGIDEFDDCILKAIFSSQGKLGNKLKQAMYFDQLDVAKRALSEASKNGQHNEIAACINDNLMAAMMHNKPHFVELYLGFDAKIYELKPSEEVAKTNITALDELPSFALAIEELYKREAKKPHSHVQRLVSLSNTDVLGRHYRGRDLANTRAYNVLRMDQIFARLVSKDFSVNRDFTIYDSKYDKVPGIQFRRTAQASHMLFLWAICLDRFRMARHFWLIGDQSIINALVASRILERLSTHRALQGPHLAEERAKMQHNAKKFEELAVGVLGECHGSDSHMASEMLHSKNDMFNKKNAINIAYDAKSLAFLSHPATQSVINADWYGHLKSVTSFWAVLFAFFFPFFVLPFINFSGAHRLRRKFAKFYSAPYTRFISDLLSHFVLCVVTSYFVLDKLEDTISAIEWILLVWFVALLLEELRQMIFCDGIAEYISDTWNRLDLIMITLFFVGFFTHASDPSNQDSKVVSKGIHAFLVVVLWLRFMRYYALSKNLGPKLIMMMEMMKDVSTFVFLLLIFLIGYGVAAQSLLSPDEDFSSRTFIGVLFRPYFQIYGELFLDDLNSEANCLGDTPFTECSRETVRMVPFFLAVYILGSNVLLVNLLIAMFNDTYMKVQEAAEDLWRKQNYELCAEYKDRPFLPAPFILLAHVHMLFMRLLRLCGVHTQEHEKIQDDETKRKITTFEELNTDKFLRRWERERQEMLEARVKMTNDNVVQAMGMMDQLLEHMISFRFSLDQQATKIPINRLNSAVAVHGHTAEAAEWYVPPEEYPKSGGVKRYLIDASMVPLSIMCPSYDPVEYTHPSVAAQPVWADPADPRKIKFNVKDEVNGKVVDRTSCHPSGISIDSNTGRPINPWGRTGMTGRGLLGKWGVNQAADTVVTRWKRSPDGSILERDGKKVLEFVAIQRQDNKMWAIPGGFVDNGEDVALTSGREFMEEALGMGTSADLMSAESKDSLAALFSSGTIVARIYCEDPRNTDNAWVETTCVNFHDESGRHAARLKLQGGDDAEHARWMMVHGGLNLFASHRTLLQHVTSALNAYF 8srg A 3.03 BS02 AMP A 1 W1264 F1372 D1460 W1141 F1249 D1332 ? 0005216,0005261,0005262,0005886,0006811,0016020,0055085,0070588,0098655 F2UB89 1502 VAAKTLLIENEDGKGSTRMEVQDFMKRFHMHASEDDKTGSPSTAWGTLRFPTKEATAPYLRLSVNDDPEDALLFVKAMLAQKYGETYDRPSLILSVTGGARNFTLPPRLETAIAKGLRLAAQRTNAWVVTGGTNTGVMKLTGQIMEALSKTQSHFIPPTIGIATYGVIIGGDDMTRGEPPKIGLEYEMHKKDPPKTTPLDDNHNLFLLVDDGSTNKFGKEIKFRAAFENAAGQAFAAPVVTIVVQGGPGTLGTALQAVRQGTPIVVVDGSGLAADVLAYAYNFMHNPLTRFKSYTIDDLRQKVAQTFNPKSSQQLTNLLDSALECVQDPNLVVVYSLQESGIDEFDDCILKAIFSSQGKLGNKLKQAMYFDQLDVAKRALSEASKNGQHNEIAACINDNLMAAMMHNKPHFVELYLGFDAKIYELKPSEEVAKTNITALDELPSFALAIEELYKREAKKPHSHVQRLVSLSNTDVLGRHYRGRDLANTRAYNVLRMDQIFARLVSKDFSVNRDFTIYDSKYDKVPGIQFRRTAQASHMLFLWAICLDRFRMARHFWLIGDQSIINALVASRILERLSTHRALQGPHLAEERAKMQHNAKKFEELAVGVLGECHGSDSHMASEMLHSKNDMFNKKNAINIAYDAKSLAFLSHPATQSVINADWYGHLKSVTSFWAVLFAFFFPFFVLPFINFSGAHRLRRKFAKFYSAPYTRFISDLLSHFVLCVVTSYFVLDKLEDTISAIEWILLVWFVALLLEELRQMIFCDGIAEYISDTWNRLDLIMITLFFVGFFTHASDPSNQDSKVVSKGIHAFLVVVLWLRFMRYYALSKNLGPKLIMMMEMMKDVSTFVFLLLIFLIGYGVAAQSLLSPDEDFSSRTFIGVLFRPYFQIYGELFLDDLNSEANCLGDTPFTECSRETVRMVPFFLAVYILGSNVLLVNLLIAMFNDTYMKVQEAAEDLWRKQNYELCAEYKDRPFLPAPFILLAHVHMLFMRLLRLCGVHTQEHEKIQDDETKRKITTFEELNTDKFLRRWERERQEMLEARVKMTNDNVVQAMGMMDQLLEHMISFRFSLDQQANRLNSAVAVHGHTAEAAEWYVPPEEYPKSGGVKRYLIDASMVPLSIMCPSYDPVEYTHPSVAAQPVWADPADPRKIKFNVKDEVNGKVVDRTSCHPSGISIDSNTGRPINPWGRTGMTGRGLLGKWGVNQAADTVVTRWKRSPDGSILERDGKKVLEFVAIQRQDNKMWAIPGGFVDNGEDVALTSGREFMEEALGMGMSAESKDSLAALFSSGTIVARIYCEDPRNTDNAWVETTCVNFHDESGRHAARLKLQGGDDAEHARWMMVHGGLNLFASHRTLLQHVTSALNAYF 8srg B 3.03 BS03 AMP B 1 W1264 F1372 D1460 W1141 F1249 D1332 ? 0005216,0005261,0005262,0005886,0006811,0016020,0055085,0070588,0098655 F2UB89 1502 VAAKTLLIENEDGKGSTRMEVQDFMKRFHMHASEDDKTGSPSTAWGTLRFPTKEATAPYLRLSVNDDPEDALLFVKAMLAQKYGETYDRPSLILSVTGGARNFTLPPRLETAIAKGLRLAAQRTNAWVVTGGTNTGVMKLTGQIMEALSKTQSHFIPPTIGIATYGVIIGGDDMTRGEPPKIGLEYEMHKKDPPKTTPLDDNHNLFLLVDDGSTNKFGKEIKFRAAFENAAGQAFAAPVVTIVVQGGPGTLGTALQAVRQGTPIVVVDGSGLAADVLAYAYNFMHNPLTRFKSYTIDDLRQKVAQTFNPKSSQQLTNLLDSALECVQDPNLVVVYSLQESGIDEFDDCILKAIFSSQGKLGNKLKQAMYFDQLDVAKRALSEASKNGQHNEIAACINDNLMAAMMHNKPHFVELYLGFDAKIYELKPSEEVAKTNITALDELPSFALAIEELYKREAKKPHSHVQRLVSLSNTDVLGRHYRGRDLANTRAYNVLRMDQIFARLVSKDFSVNRDFTIYDSKYDKVPGIQFRRTAQASHMLFLWAICLDRFRMARHFWLIGDQSIINALVASRILERLSTHRALQGPHLAEERAKMQHNAKKFEELAVGVLGECHGSDSHMASEMLHSKNDMFNKKNAINIAYDAKSLAFLSHPATQSVINADWYGHLKSVTSFWAVLFAFFFPFFVLPFINFSGAHRLRRKFAKFYSAPYTRFISDLLSHFVLCVVTSYFVLDKLEDTISAIEWILLVWFVALLLEELRQMIFCDGIAEYISDTWNRLDLIMITLFFVGFFTHASDPSNQDSKVVSKGIHAFLVVVLWLRFMRYYALSKNLGPKLIMMMEMMKDVSTFVFLLLIFLIGYGVAAQSLLSPDEDFSSRTFIGVLFRPYFQIYGELFLDDLNSEANCLGDTPFTECSRETVRMVPFFLAVYILGSNVLLVNLLIAMFNDTYMKVQEAAEDLWRKQNYELCAEYKDRPFLPAPFILLAHVHMLFMRLLRLCGVHTQEHEKIQDDETKRKITTFEELNTDKFLRRWERERQEMLEARVKMTNDNVVQAMGMMDQLLEHMISFRFSLDQQANRLNSAVAVHGHTAEAAEWYVPPEEYPKSGGVKRYLIDASMVPLSIMCPSYDPVEYTHPSVAAQPVWADPADPRKIKFNVKDEVNGKVVDRTSCHPSGISIDSNTGRPINPWGRTGMTGRGLLGKWGVNQAADTVVTRWKRSPDGSILERDGKKVLEFVAIQRQDNKMWAIPGGFVDNGEDVALTSGREFMEEALGMGMSAESKDSLAALFSSGTIVARIYCEDPRNTDNAWVETTCVNFHDESGRHAARLKLQGGDDAEHARWMMVHGGLNLFASHRTLLQHVTSALNAYF 8srg C 3.03 BS03 AMP C 1 W1264 F1372 D1460 W1141 F1249 D1332 ? 0005216,0005261,0005262,0005886,0006811,0016020,0055085,0070588,0098655 F2UB89 1502 VAAKTLLIENEDGKGSTRMEVQDFMKRFHMHASEDDKTGSPSTAWGTLRFPTKEATAPYLRLSVNDDPEDALLFVKAMLAQKYGETYDRPSLILSVTGGARNFTLPPRLETAIAKGLRLAAQRTNAWVVTGGTNTGVMKLTGQIMEALSKTQSHFIPPTIGIATYGVIIGGDDMTRGEPPKIGLEYEMHKKDPPKTTPLDDNHNLFLLVDDGSTNKFGKEIKFRAAFENAAGQAFAAPVVTIVVQGGPGTLGTALQAVRQGTPIVVVDGSGLAADVLAYAYNFMHNPLTRFKSYTIDDLRQKVAQTFNPKSSQQLTNLLDSALECVQDPNLVVVYSLQESGIDEFDDCILKAIFSSQGKLGNKLKQAMYFDQLDVAKRALSEASKNGQHNEIAACINDNLMAAMMHNKPHFVELYLGFDAKIYELKPSEEVAKTNITALDELPSFALAIEELYKREAKKPHSHVQRLVSLSNTDVLGRHYRGRDLANTRAYNVLRMDQIFARLVSKDFSVNRDFTIYDSKYDKVPGIQFRRTAQASHMLFLWAICLDRFRMARHFWLIGDQSIINALVASRILERLSTHRALQGPHLAEERAKMQHNAKKFEELAVGVLGECHGSDSHMASEMLHSKNDMFNKKNAINIAYDAKSLAFLSHPATQSVINADWYGHLKSVTSFWAVLFAFFFPFFVLPFINFSGAHRLRRKFAKFYSAPYTRFISDLLSHFVLCVVTSYFVLDKLEDTISAIEWILLVWFVALLLEELRQMIFCDGIAEYISDTWNRLDLIMITLFFVGFFTHASDPSNQDSKVVSKGIHAFLVVVLWLRFMRYYALSKNLGPKLIMMMEMMKDVSTFVFLLLIFLIGYGVAAQSLLSPDEDFSSRTFIGVLFRPYFQIYGELFLDDLNSEANCLGDTPFTECSRETVRMVPFFLAVYILGSNVLLVNLLIAMFNDTYMKVQEAAEDLWRKQNYELCAEYKDRPFLPAPFILLAHVHMLFMRLLRLCGVHTQEHEKIQDDETKRKITTFEELNTDKFLRRWERERQEMLEARVKMTNDNVVQAMGMMDQLLEHMISFRFSLDQQANRLNSAVAVHGHTAEAAEWYVPPEEYPKSGGVKRYLIDASMVPLSIMCPSYDPVEYTHPSVAAQPVWADPADPRKIKFNVKDEVNGKVVDRTSCHPSGISIDSNTGRPINPWGRTGMTGRGLLGKWGVNQAADTVVTRWKRSPDGSILERDGKKVLEFVAIQRQDNKMWAIPGGFVDNGEDVALTSGREFMEEALGMGMSAESKDSLAALFSSGTIVARIYCEDPRNTDNAWVETTCVNFHDESGRHAARLKLQGGDDAEHARWMMVHGGLNLFASHRTLLQHVTSALNAYF 8srg D 3.03 BS05 AMP D 1 W1264 F1372 D1460 W1141 F1249 D1332 ? 0005216,0005261,0005262,0005886,0006811,0016020,0055085,0070588,0098655 F2UB89 6004 VAAKTLLIENEDGKGSTRMEVQDFMKRFHMHASEDDKTGSPSTAWGTLRFPTKEATAPYLRLSVNDDPEDALLFVKAMLAQKYGETYDRPSLILSVTGGARNFTLPPRLETAIAKGLRLAAQRTNAWVVTGGTNTGVMKLTGQIMEALSKTQSHFIPPTIGIATYGVIIGGDDMTRGEPPKIGLEYEMHKKDPPKTTPLDDNHNLFLLVDDGSTNKFGKEIKFRAAFENAAGQAFAAPVVTIVVQGGPGTLGTALQAVRQGTPIVVVDGSGLAADVLAYAYNFMHNPLTRFKSYTIDDLRQKVAQTFNPKSSQQLTNLLDSALECVQDPNLVVVYSLQESGIDEFDDCILKAIFSSQGKLGNKLKQAMYFDQLDVAKRALSEASKNGQHNEIAACINDNLMAAMMHNKPHFVELYLGFDAKIYELKPSEEVAKTNITALDELPSFALAIEELYKREAKKPHSHVQRLVSLSNTDVLGRHYRGRDLANTRAYNVLRMDQIFARLVSKDFSVNRDFTIYDSKYDKVPGIQFRRTAQASHMLFLWAICLDRFRMARHFWLIGDQSIINALVASRILERLSTHRALQGPHLAEERAKMQHNAKKFEELAVGVLGECHGSDSHMASEMLHSKNDMFNKKNAINIAYDAKSLAFLSHPATQSVINADWYGHLKSVTSFWAVLFAFFFPFFVLPFINFSGAHRLRRKFAKFYSAPYTRFISDLLSHFVLCVVTSYFVLDKLEDTISAIEWILLVWFVALLLEELRQMIFCDGIAEYISDTWNRLDLIMITLFFVGFFTHASDPSNQDSKVVSKGIHAFLVVVLWLRFMRYYALSKNLGPKLIMMMEMMKDVSTFVFLLLIFLIGYGVAAQSLLSPDEDFSSRTFIGVLFRPYFQIYGELFLDDLNSEANCLGDTPFTECSRETVRMVPFFLAVYILGSNVLLVNLLIAMFNDTYMKVQEAAEDLWRKQNYELCAEYKDRPFLPAPFILLAHVHMLFMRLLRLCGVHTQEHEKIQDDETKRKITTFEELNTDKFLRRWERERQEMLEARVKMTNDNVVQAMGMMDQLLEHMISFRFSLDQQANRLNSAVAVHGHTAEAAEWYVPPEEYPKSGGVKRYLIDASMVPLSIMCPSYDPVEYTHPSVAAQPVWADPADPRKIKFNVKDEVNGKVVDRTSCHPSGISIDSNTGRPINPWGRTGMTGRGLLGKWGVNQAADTVVTRWKRSPDGSILERDGKKVLEFVAIQRQDNKMWAIPGGFVDNGEDVALTSGREFMEEALGMGMSAESKDSLAALFSSGTIVARIYCEDPRNTDNAWVETTCVNFHDESGRHAARLKLQGGDDAEHARWMMVHGGLNLFASHRTLLQHVTSALNAYF 8sv8 A 3.38 BS01 AMP B 1 G439 G441 A442 D468 D470 L516 L539 D540 G419 G421 A422 D448 D450 L496 L519 D520 6.2.1.- 0004842,0005515,0005524,0005634,0005654,0005737,0005829,0006974,0008641,0016567,0016874,0019782,0019941,0032020,0032446,0036211,0045087 P41226 37553340 1101 VLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLELASASAEFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFAPAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTAFPPLHYEL 8t5n A 1.65 BS02 AMP A 1 R195 E197 F205 R206 T207 F210 Q212 E282 L283 A324 G326 R329 R142 E144 F152 R153 T154 F157 Q159 E229 L230 A271 G273 R276 6.1.1.14 0000166,0004081,0004812,0004820,0005524,0005737,0005829,0005886,0006412,0006418,0006426,0015966,0046983,0070062,1903561,1990742 P9WFV7 512 PVIDTVVNLAKRRGFVYPSGEIYGGTKSAWDYGPLGVELKENIKRQWWRSVVTGRDDVVGIDSSIILPREVWVASGHVDVFHDPREFNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPATAKEWHQYWIDNRLQWYIDLGIRRENLRLWEHPKDKLSHYSDRTVDIEYKFGFMGNPWGELEGVANRTDFDLSTHARHSGVDLSFYDQINDVRYTPYVIEPAAGLTRSFMAFLIDAYTEDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLGAELRKCWNIDFDDAGAIGRRYRRQDEVGTPFCVTVDFDSLQDNAVTVRERDAMTQDRVAMSSVADYLAVRLKGS 8tkb A 1.71 BS01 AMP A 1 H95 T97 N101 G104 I105 I110 K111 R115 H119 H95 T97 N101 G104 I105 I110 K111 R115 H119 0000215,0006388,0016740,0016772 O57899 201 SRFKVSKLMAYILRHSPWEFGLEPDEEGFVSIEELVNAVRKVYPWVTEEYIREIVERDEKGRYEIRGNKIRARYGHSYPVILRHEEDKESKVLYHGTVRRNLKGIMREGIKPMKRQYVHLSINYEDAYNTGMRHGEDVVVLIIDAECLRNKGYKILKAGKKVRIVKHVPVDCISGIL 8tkb A 1.71 BS02 AMP A 2 R14 K60 R62 Y74 G75 R133 R14 K60 R62 Y74 G75 R133 0000215,0006388,0016740,0016772 O57899 202 SRFKVSKLMAYILRHSPWEFGLEPDEEGFVSIEELVNAVRKVYPWVTEEYIREIVERDEKGRYEIRGNKIRARYGHSYPVILRHEEDKESKVLYHGTVRRNLKGIMREGIKPMKRQYVHLSINYEDAYNTGMRHGEDVVVLIIDAECLRNKGYKILKAGKKVRIVKHVPVDCISGIL 8u2t A 1.65 BS01 AMP A 1 G439 E440 P441 T464 W465 W466 Q467 T468 D552 R567 R578 G397 E398 P399 T422 W423 W424 Q425 T426 D510 R525 R536 6.2.1.1 0003987,0005524,0006085,0016208,0016874,0019427 A4I093 807 DSNVVEPTEANGKKSHVGPHLGSRMRIYEYSIEHNDAFWAEIARRDFYWKTTWPDDQHVKSYNFDKSKGPIFVKWFEGAVTNVCYNALDRHLPAHKDRVCFYFEGNDPSVTEAVTYGSMYTRVVELANVLKYQYGIAKGDRVGLYLPMIPFAAVAMLACARIGAVITVIFGGFSAQALSSRLKDAQTKLLITADASARGTKPIPLKDVADEALKECEEEGMSIACLVAENMSCKMKEGRDTWYGDALARLTPEQHEECPVEWMDAEDVLFLLYTSGSTGKPKAIVHTTAGYMVYASTTFMYSFDYHMDDVYFCTADIGWITGHSYVVYGPMIHCATSVLFEGVPNYPDYSRWWQLVEKYKVSILYTAPTAIRSLMQAGDDYVKVGNRSTLRVLGSVGEPINVEAWKWLRDVGGEGHCDVSDTWWQTETGGHMITPMPGCTPMKPGSATLPFFGVQPVILDPMKLHEKQGPAEGLLAIRAPWPGMARTIYGDHARFEKTYFGVDGYYMTGDGARRDSDGYYWITGRVDDVLNVSGHRIGTSEIEDAVNTHPAVVESAVVGFPHNIKGEGIYVFLTFRQGTEVTPELLAAVKATVRKVIGPLATPDVMQVARVGLPKTRSGKIVRRILRKVSAGQYTELGDTSTLANPDVVEDLIAEHQRLCS 8u2u A 1.97 BS01 AMP A 1 G439 E440 P441 T464 W465 Q467 T468 D552 I564 R567 N573 R578 G398 E399 P400 T423 W424 Q426 T427 D511 I523 R526 N532 R537 6.2.1.1 0003987,0005524,0006085,0016208,0016874,0019427 A4I093 805 DSNVVEPTEANGKKSHVGPHLGSRMRIYEYSIEHNDAFWAEIARRDFYWKTTWPDDQHVKSYNFDKSKGPIFVKWFEGAVTNVCYNALDRHLPAHKDRVCFYFEGNDPSVTEAVTYGSMYTRVVELANVLKYQYGIAKGDRVGLYLPMIPFAAVAMLACARIGAVITVIFGGFSAQALSSRLKDAQTKLLITADASARGTKPIPLKDVADEALKECEEEGMSIACLVAENMQSCKMKEGRDTWYGDALARLTPEQHEECPVEWMDAEDVLFLLYTSGSTGKPKAIVHTTAGYMVYASTTFMYSFDYHMDDVYFCTADIGWITGHSYVVYGPMIHCATSVLFEGVPNYPDYSRWWQLVEKYKVSILYTAPTAIRSLMQAGDDYVKVGNRSTLRVLGSVGEPINVEAWKWLRDVGGEGHCDVSDTWWQTETGGHMITPMPGCTPMKPGSATLPFFGVQPVILDPMKLHEKQGPAEGLLAIRAPWPGMARTIYGDHARFEKTYFGVDGYYMTGDGARRDSDGYYWITGRVDDVLNVSGHRIGTSEIEDAVNTHPAVVESAVVGFPHNIKGEGIYVFLTFRQGTEVTPELLAAVKATVRKVIGPLATPDVMQVARVGLPKTRSGKIVRRILRKVSAGQYTELGDTSTLANPDVVEDLIAEHQRLC 8u6x A 2.44 BS03 AMP A 1 K22 L23 E61 F91 I122 M149 K167 K22 L23 E61 F91 I122 M149 K167 0003910,0005524,0006281,0006310 38245708 301 ADLMLAQEYKGQDIAGWAMSEKLDGVRAYWDGKHLISRQGYAFTPPKGFTAQFPPYPLDGELYSGRGQFEQISATVRSVSSDWRGIRLHVFDVPKAQGNLYQRLAVATQWLKTHPNAPITIIPQIKVRDRRHAMDFLKQIEAQGGEGVMLRQPESRYSGGRSSQLLKLKSQYDDECTVTRHYEGKGRNAGRLGAVGCKNRHGEFRIGSGFKDKDRDNPPKIGTLITYRYRGFTRKGTPKFATFVRVR 8uce A 2.12 BS01 AMP A 1 E90 K92 V93 N97 E144 F169 K229 K238 E90 K92 V93 N97 E144 F169 K229 K238 ? 0005524,0016874,0046872 A0A075LQ94 38421610 401 MVSSYFKGILLNLGLDEERIEVLENKGGIVEDEFEGMRYLRLKDSARSLRRGTVVFDEHNIILGFPHIKRVVQLENGIRRAFKRKPFYVEEKVDGYNVRVAKIGEKILVFTRGGFVCPFTTERIEDFITLDFFKDYPNMVLCGEMAGPESPYLVEGPPYVKEDIQFFLFDIQEKKTGRSLPVEERLKLAEEYGIPSVEVFGLYDLSRIDELHALIDRLTKEKREGIVMKSPDMKKIVKYVTPYANINDIKIGARIFFDLPHGYFMQRIKRLAFYLAERKIRGEEFDEYARALGKVLLEPFVESIWDISSGDDEIAELFTVRVKKLETAHKMVTHFERLRLKIHIDDIEVLDNGYWRITFKRVYPDATKEMRELWNGHAFV 8uce B 2.12 BS01 AMP B 1 I68 K92 V93 N97 E144 F169 K229 K238 I67 K91 V92 N96 E143 F168 K228 K237 ? 0005524,0016874,0046872 A0A075LQ94 38421610 401 MVSSYFKGILLNLGLEERIEVLENKGGIVEDEFEGMRYLRLKDSARSLRRGTVVFDEHNIILGFPHIKRVVQLENGIRRAFKRKPFYVEEKVDGYNVRVAKIGEKILVFTRGGFVCPFTTERIEDFITLDFFKDYPNMVLCGEMAGPESPYLVEGPPYVKEDIQFFLFDIQEKKTGRSLPVEERLKLAEEYGIPSVEVFGLYDLSRIDELHALIDRLTKEKREGIVMKSPDMKKIVKYVTPYANINDIKIGARIFFDLPHGYFMQRIKRLAFYLAERKIRGEEFDEYARALGKVLLEPFVESIWDISSGDDEIAELFTVRVKKLETAHKMVTHFERLRLKIHIDDIEVLDNGYWRITFKRVYPDATKEMRELWNGHAFV 8uci A 2.14 BS01 AMP A 1 I68 R70 K92 V93 E144 F169 K229 I68 R70 K92 V93 E144 F169 K229 6.5.1.3 0005524,0016874,0046872 A0A075LQ94 38421610 401 MVSSYFKGILLNLGLDEERIEVLENKGGIVEDEFEGMRYLRLKDSARSLRRGTVVFDEHNIILGFPHIKRVVQLENGIRRAFKRKPFYVEEKVDGYNVRVAKIGEKILVFTRGGFVCPFTTERIEDFITLDFFKDYPNMVLCGEMAGPESPYLVEGPPYVKEDIQFFLFDIQEKKTGRSLPVEERLKLAEEYGIPSVEVFGLYDLSRIDELHALIDRLTKEKREGIVMKSPDMKKIVGYVTPYANINDIKIGARIFFDLPHGYFMQRIKRLAFYLAERKIRGEEFDEYARALGKVLLEPFVESIWDISSGDDEIAELFTVRVKKLETAHKMVTHFERLRLKIHIDDIEVLDNGYWRITFKRVYPDATKEMRELWNGHAFVD 8uci B 2.14 BS01 AMP B 1 I68 R70 K92 V93 N97 E144 F169 K229 I68 R70 K92 V93 N97 E144 F169 K229 6.5.1.3 0005524,0016874,0046872 A0A075LQ94 38421610 401 MVSSYFKGILLNLGLDEERIEVLENKGGIVEDEFEGMRYLRLKDSARSLRRGTVVFDEHNIILGFPHIKRVVQLENGIRRAFKRKPFYVEEKVDGYNVRVAKIGEKILVFTRGGFVCPFTTERIEDFITLDFFKDYPNMVLCGEMAGPESPYLVEGPPYVKEDIQFFLFDIQEKKTGRSLPVEERLKLAEEYGIPSVEVFGLYDLSRIDELHALIDRLTKEKREGIVMKSPDMKKIVGYVTPYANINDIKIGARIFFDLPHGYFMQRIKRLAFYLAERKIRGEEFDEYARALGKVLLEPFVESIWDISSGDDEIAELFTVRVKKLETAHKMVTHFERLRLKIHIDDIEVLDNGYWRITFKRVYPDATKEMRELWNGHAFV 8uzn A 2.15 BS01 AMP A 1 I149 G150 K176 S178 E179 G209 G213 F227 G230 S233 K236 I147 G148 K174 S176 E177 G207 G211 F225 G228 S231 K234 1.2.1.8 0000166,0008802,0016491,0016620,0019285,0046872 A0A0H3FPU4 501 RMAEQQLYIHGKFVAATSGKTFETINPATGEVLATVQAAGREDVDRAVKSAQQGQKVWAAMSAMARSRILRKAVDILRERNDELARLETLDTGKPLSETAAVDIVTGADVLEYYAGLIPALEGSQIPLRDSSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYREAGLPDGVFNVLPGIGAETGQYLTEHPDIAKISFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIIAEDANLDLAADIAMMANFYSSGQVCTNGTRVFVPAKFKAEFEHKILERVGRIRAGDLFADDTNFGPLVSFPHRQNVLRYIESGKSEGARLLCGGDVLKGEGFDNGAWVAPTVFTDCTDDMTIVREEIFGPVMSILSYDDEAEVIRRANATEYGLAAGVVTPDLNRAHRIIHQLEAGICWINSWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMGPFQSIF 8uzn B 2.15 BS01 AMP B 1 I149 G150 K176 E179 G209 G213 F227 G230 S233 K236 I147 G148 K174 E177 G207 G211 F225 G228 S231 K234 1.2.1.8 0000166,0008802,0016491,0016620,0019285,0046872 A0A0H3FPU4 501 RMAEQQLYIHGKFVAATSGKTFETINPATGEVLATVQAAGREDVDRAVKSAQQGQKVWAAMSAMARSRILRKAVDILRERNDELARLETLDTGKPLSETAAVDIVTGADVLEYYAGLIPALEGSQIPLRDSSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYREAGLPDGVFNVLPGIGAETGQYLTEHPDIAKISFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIIAEDANLDLAADIAMMANFYSSGQVCTNGTRVFVPAKFKAEFEHKILERVGRIRAGDLFADDTNFGPLVSFPHRQNVLRYIESGKSEGARLLCGGDVLKGEGFDNGAWVAPTVFTDCTDDMTIVREEIFGPVMSILSYDDEAEVIRRANATEYGLAAGVVTPDLNRAHRIIHQLEAGICWINSWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMGPFQSIF 8uzn C 2.15 BS01 AMP C 1 I149 G150 K176 E179 G209 G213 F227 G230 S233 V237 I147 G148 K174 E177 G207 G211 F225 G228 S231 V235 1.2.1.8 0000166,0008802,0016491,0016620,0019285,0046872 A0A0H3FPU4 501 RMAEQQLYIHGKFVAATSGKTFETINPATGEVLATVQAAGREDVDRAVKSAQQGQKVWAAMSAMARSRILRKAVDILRERNDELARLETLDTGKPLSETAAVDIVTGADVLEYYAGLIPALEGSQIPLRDSSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYREAGLPDGVFNVLPGIGAETGQYLTEHPDIAKISFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIIAEDANLDLAADIAMMANFYSSGQVCTNGTRVFVPAKFKAEFEHKILERVGRIRAGDLFADDTNFGPLVSFPHRQNVLRYIESGKSEGARLLCGGDVLKGEGFDNGAWVAPTVFTDCTDDMTIVREEIFGPVMSILSYDDEAEVIRRANATEYGLAAGVVTPDLNRAHRIIHQLEAGICWINSWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMGPFQSIF 8uzn D 2.15 BS01 AMP D 1 I149 G150 K176 E179 G209 G213 F227 G230 S233 V237 I145 G146 K172 E175 G205 G209 F223 G226 S229 V233 1.2.1.8 0000166,0008802,0016491,0016620,0019285,0046872 A0A0H3FPU4 501 AEQQLYIHGKFVAATSGKTFETINPATGEVLATVQAAGREDVDRAVKSAQQGQKVWAAMSAMARSRILRKAVDILRERNDELARLETLDTGKPLSETAAVDIVTGADVLEYYAGLIPALEGSQIPLRDSSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYREAGLPDGVFNVLPGIGAETGQYLTEHPDIAKISFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIIAEDANLDLAADIAMMANFYSSGQVCTNGTRVFVPAKFKAEFEHKILERVGRIRAGDLFADDTNFGPLVSFPHRQNVLRYIESGKSEGARLLCGGDVLKGEGFDNGAWVAPTVFTDCTDDMTIVREEIFGPVMSILSYDDEAEVIRRANATEYGLAAGVVTPDLNRAHRIIHQLEAGICWINSWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMGPFQSIF 8v4o A 2.7 BS01 AMP A 1 G417 E418 P419 T442 Y443 W444 Q445 T446 D532 I544 R547 R558 G398 E399 P400 T423 Y424 W425 Q426 T427 D513 I525 R528 R539 6.2.1.1 0003987,0005524,0016208,0016874,0019427 Q8NJN3 708 QTHNVVHEANGVKLRETPKEFFERQPNKGHIHDVNQYKQMYEQSIKDPQGFFGPLAKELLSWDHDFHTVKSGTLKNGDAAWFLGGELNASYNCVDRHAFANPDKPALICEADDEKDSHILTYGDLLREVSKVAGVLQSWGIKKGDTVAVYLPMNAQAIIAMLAIARLGAAHSVIFAGFSAGSIKDRVNDASCKALITCDEGKRGGRTTNIKKLCDEALVDCPTVEKVLVYKRTNNPEIHLTEGRDYYWDVETAKFPGYLPPVSVNSEDPLFLLYTSGSTGTPKGVVHSTAGYLLGAALSTKYIFDIHPEDILFTAGDVGWITGHTYALYGPLLLGVPTIIFEGTPAYPDYGRFWQIVEKHKATHFYVAPTALRLLRKAGEQEIAKYDLSSLRTLGSVGEPISPDIWEWYNEFVGKNQCHISDTYWQTESGSHLIAPLAGVVPNKPGSASYPFFGIDAALIDPVTGVEIEGNDAEGVLAIKDHWPSMARTVYKNHTKYMDTYMNPYPGYYFTGDGAARDHDGYYWIRGRVDDVVNVSGHRLSTAEIEAALIEDKKVSEAAVVGIHDDITGQAVIAYVALKEDSEGLRKELVLQVRKTIGPFAAPKSVIIVQDLPKTRSGKIMRRILRKVSSNEADQLGDISTLSNPQSVEGIISAFGAQFG 8v4o B 2.7 BS01 AMP B 1 I340 G417 E418 P419 T442 Y443 W444 Q445 D532 I315 G392 E393 P394 T417 Y418 W419 Q420 D507 6.2.1.1 0003987,0005524,0016208,0016874,0019427 Q8NJN3 707 THNVVHEANGVKLRETPKEFFERQPNKGHIHDVNQYKQMYEQSIKDPQGFFGPLAKELLSWDHDFHTVKSGTLKNGDAAWFLGGELNASYNCVDRHAFANPDKPALICEADDEKDSHILTYGDLLREVSKVAGVLQSWGIKKGDTVAVYLPMNAQAIIAMLAIARLGAAHSVIFAGFSAGSIKDRVNDASCKALITCDEGKRGGRTTNIKKLCDEALVDCPTVEKVLVYKRTNNPEIHLTEGRDYYWDVETAKFPGYLPPVSVNSEDPLFLLYTTPKGVVHSTAGYLLGAALSTKYIFDIHPEDILFTAGDVGWITGHTYALYGPLLLGVPTIIFEGTPAYPDYGRFWQIVEKHKATHFYVAPTALRLLRKAGEQEIAKYDLSSLRTLGSVGEPISPDIWEWYNEFVGKNQCHISDTYWQTESGSHLIAPLAGVVPNKPGSASYPFFGIDAALIDPVTGVEIEGNDAEGVLAIKDHWPSMARTVYKNHTKYMDTYMNPYPGYYFTGDGAARDHDGYYWIRGRVDDVVNVSGHRLSTAEIEAALIEDKKVSEAAVVGIHDDITGQAVIAYVALGLRKELVLQVRKTIGPFAAPKSVIIVQDIMRRILRKVSSNLSNPQSVEGIISAFGA 8v4o C 2.7 BS01 AMP C 1 V416 G417 P419 D441 T442 Y443 W444 Q445 T446 D532 I544 V391 G392 P394 D416 T417 Y418 W419 Q420 T421 D507 I519 6.2.1.1 0003987,0005524,0016208,0016874,0019427 Q8NJN3 701 THNVVHEANGVKLRETPKEFFERQPNKGHIHDVNQYKQMYEQSIKDPQGFFGPLAKELLSWDHDFHTVKSGTLKNGDAAWFLGGELNASYNCVDRHAFANPDKPALICEADDEKDSHILTYGDLLREVSKVAGVLQSWGIKKGDTVAVYLPMNAQAIIAMLAIARLGAAHSVIFAGFSAGSIKDRVNDASCKALITCDEGKRGGRTTNIKKLCDEALVDCPTVEKVLVYKRTNNPEIHLTEGRDYYWDVETAKFPGYLPPVSVNSEDPLFLLYTTPKGVVHSTAGYLLGAALSTKYIFDIHPEDILFTAGDVGWITGHTYALYGPLLLGVPTIIFEGTPAYPDYGRFWQIVEKHKATHFYVAPTALRLLRKAGEQEIAKYDLSSLRTLGSVGEPISPDIWEWYNEFVGKNQCHISDTYWQTESGSHLIAPLAGVVPNKPGSASYPFFGIDAALIDPVTGVEIEGNDAEGVLAIKDHWPSMARTVYKNHTKYMDTYMNPYPGYYFTGDGAARDHDGYYWIRGRV 8v4r A 2.7 BS01 AMP A 1 G417 E418 P419 T442 Y443 Q445 T446 D532 I544 R547 R558 G398 E399 P400 T423 Y424 Q426 T427 D513 I525 R528 R539 6.2.1.1 0003987,0005524,0016208,0016874,0019427 Q8NJN3 701 QTHNVVHEANGVKLRETPKEFFERQPNKGHIHDVNQYKQMYEQSIKDPQGFFGPLAKELLSWDHDFHTVKSGTLKNGDAAWFLGGELNASYNCVDRHAFANPDKPALICEADDEKDSHILTYGDLLREVSKVAGVLQSWGIKKGDTVAVYLPMNAQAIIAMLAIARLGAAHSVIFAGFSAGSIKDRVNDASCKALITCDEGKRGGRTTNIKKLCDEALVDCPTVEKVLVYKRTNNPEIHLTEGRDYYWDVETAKFPGYLPPVSVNSEDPLFLLYTSGSTGTPKGVVHSTAGYLLGAALSTKYIFDIHPEDILFTAGDVGWITGHTYALYGPLLLGVPTIIFEGTPAYPDYGRFWQIVEKHKATHFYVAPTALRLLRKAGEQEIAKYDLSSLRTLGSVGEPISPDIWEWYNEFVGKNQCHISDTYWQTESGSHLIAPLAGVVPNKPGSASYPFFGIDAALIDPVTGVEIEGNDAEGVLAIKDHWPSMARTVYKNHTKYMDTYMNPYPGYYFTGDGAARDHDGYYWIRGRVDDVVNVSGHRLSTAEIEAALIEDKKVSEAAVVGIHDDITGQAVIAYVALKEGNSDEDSEGLRKELVLQVRKTIGPFAAPKSVIIVQDLPKTRSGKIMRRILRKVSSNEADQLGDISTLSNPQSVEGIISAFGAQFGK 8v4r B 2.7 BS01 AMP B 1 G417 E418 P419 D441 T442 Y443 Q445 T446 D532 I544 R547 R558 G394 E395 P396 D418 T419 Y420 Q422 T423 D509 I521 R524 R535 6.2.1.1 0003987,0005524,0016208,0016874,0019427 Q8NJN3 701 QTHNVVHEANGVKLRETPKEFFERQPNKGHIHDVNQYKQMYEQSIKDPQGFFGPLAKELLSWDHDFHTVKSGTLKNGDAAWFLGGELNASYNCVDRHAFANPDKPALICEADDEKDSHILTYGDLLREVSKVAGVLQSWGIKKGDTVAVYLPMNAQAIIAMLAIARLGAAHSVIFAGFSAGSIKDRVNDASCKALITCDEGKRGGRTTNIKKLCDEALVDCPTVEKVLVYKRTNNPEIHLTEGRDYYWDVETAKFPGYLPPVSVNSEDPLFLLYTSTPKGVVHSTAGYLLGAALSTKYIFDIHPEDILFTAGDVGWITGHTYALYGPLLLGVPTIIFEGTPAYPDYGRFWQIVEKHKATHFYVAPTALRLLRKAGEQEIAKYDLSSLRTLGSVGEPISPDIWEWYNEFVGKNQCHISDTYWQTESGSHLIAPLAGVVPNKPGSASYPFFGIDAALIDPVTGVEIEGNDAEGVLAIKDHWPSMARTVYKNHTKYMDTYMNPYPGYYFTGDGAARDHDGYYWIRGRVDDVVNVSGHRLSTAEIEAALIEDKKVSHDDITGQAVIAYVAKELVLQVRKTIGPFAAPKSVIIV 8v4r C 2.7 BS01 AMP C 1 G417 E418 P419 D441 T442 W444 Q445 T446 D532 I544 R547 R558 G398 E399 P400 D422 T423 W425 Q426 T427 D513 I525 R528 R539 6.2.1.1 0003987,0005524,0016208,0016874,0019427 Q8NJN3 701 QTHNVVHEANGVKLRETPKEFFERQPNKGHIHDVNQYKQMYEQSIKDPQGFFGPLAKELLSWDHDFHTVKSGTLKNGDAAWFLGGELNASYNCVDRHAFANPDKPALICEADDEKDSHILTYGDLLREVSKVAGVLQSWGIKKGDTVAVYLPMNAQAIIAMLAIARLGAAHSVIFAGFSAGSIKDRVNDASCKALITCDEGKRGGRTTNIKKLCDEALVDCPTVEKVLVYKRTNNPEIHLTEGRDYYWDVETAKFPGYLPPVSVNSEDPLFLLYTSGSTGTPKGVVHSTAGYLLGAALSTKYIFDIHPEDILFTAGDVGWITGHTYALYGPLLLGVPTIIFEGTPAYPDYGRFWQIVEKHKATHFYVAPTALRLLRKAGEQEIAKYDLSSLRTLGSVGEPISPDIWEWYNEFVGKNQCHISDTYWQTESGSHLIAPLAGVVPNKPGSASYPFFGIDAALIDPVTGVEIEGNDAEGVLAIKDHWPSMARTVYKNHTKYMDTYMNPYPGYYFTGDGAARDHDGYYWIRGRVDDVVNVSGHRLSTAEIEAALIEDKKVSEAAVVGIHDDITGQAVIAYVALLQVRKTIGPFAAPKSVIIV 8vdn A 2.39 BS04 AMP C 1 Y567 K568 Y569 R573 E621 F660 M723 K725 K744 Y298 K299 Y300 R304 E352 F391 M454 K456 K475 6.5.1.1 P18858 38522520 101 LDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKREAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQ 8vw0 A 1.7 BS01 AMP A 1 N114 G115 S117 T118 N179 H268 N272 R303 D318 K320 A321 S326 A329 N113 G114 S116 T117 N178 H267 N271 R302 D317 K319 A320 S325 A328 6.3.2.9 0005515,0005524,0005737,0008360,0008764,0009058,0009252,0016874,0016881,0042802,0051301,0071555 P14900 501 ADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGLDKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELSSFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALTMPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGLHVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETMEQAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELGGH 8vzl A 2.41 BS04 AMP C 1 E566 Y567 K568 Y569 R573 E621 F660 M723 K725 K744 K746 E306 Y307 K308 Y309 R313 E361 F400 M463 K465 K484 K486 6.5.1.1 P18858 38522520 101 LDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQ 8vzm A 2.51 BS04 AMP C 1 E566 Y567 K568 Y569 R573 E621 F660 M723 K725 K744 E306 Y307 K308 Y309 R313 E361 F400 M463 K465 K484 6.5.1.1 P18858 38522520 101 LDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQ 8wev A 2.29 BS01 AMP A 1 G270 A271 Y292 G293 M294 T295 D374 R389 G267 A268 Y289 G290 M291 T292 D371 R386 A0A3N2H3K2 501 MRNQGLGSWPVRRARMSPHATAVRHGGTALTYAELSRRVARLAHGLREAGVRPGDRVAYLGPNHPAYLETLFACGQAGAVFVPLNFRLGVPELDHALADSGASVLIHTPEHAETVAALAGDRLLRVPAGELEAADDEPLDLPVGLDDVCLLMYTSGRPKGAMLTHGNLTWNCVNVLVETDLASDERALVAAPLFHAAALGMVCLPTLLKGGTVILHSAFDPGAVLSAVEQERVTLVFGVPTMYQAIAAHPRWRSTDLSSLRTLLCGGAPVPADLAGRYLDRGLAFVQGYGMTEAAPGVLVLDRAHVAEKIGSAGVPSFFTDVRVAGPSGEPVPPGEKGEIVVSGPNVMKGYWGRPEATAEVLRDGWFRSGDVATVDGDGYFHVVDRLKDMIISGGENIYPAEVENELYGYPGVEACAVIGVPDPRWGEVGKAVVVPAAGSRIDGAELLAWLRTRLAGYKVPKSVEFTDRLPTTGSGKILKGEVRRR 8wev B 2.29 BS01 AMP B 1 G270 A271 P272 G291 Y292 G293 M294 T295 D374 R389 G267 A268 P269 G288 Y289 G290 M291 T292 D371 R386 A0A3N2H3K2 501 MRNQGLGSWPVRRARMSPHATAVRHGGTALTYAELSRRVARLAHGLREAGVRPGDRVAYLGPNHPAYLETLFACGQAGAVFVPLNFRLGVPELDHALADSGASVLIHTPEHAETVAALADRLLRVPAGELEAADDEPLDLPVGLDDVCLLMYTSTGRPKGAMLTHGNLTWNCVNVLVETDLASDERALVAAPLFHAAALGMVCLPTLLKGGTVILHSAFDPGAVLSAVEQERVTLVFGVPTMYQAIAAHPRWRSTDLSSLRTLLCGGAPVPADLAGRYLDRGLAFVQGYGMTEAAPGVLVLDRAHVAEKIGSAGVPSFFTDVRVAGPSGEPVPPGEKGEIVVSGPNVMKGYWGRPEATAEVLRDGWFRSGDVATVDGDGYFHVVDRLKDMIISGGENIYPAEVENELYGYPEACAVIGVPDPRWGEVGKAVVVPDGAELLAWLRTRLAGYKVPKSVEFTDRLPTTGSLKGEVRRRF 8zoz A 3.2 BS01 AMP A 1 F9 G10 D36 I37 K88 T107 F9 G10 D36 I37 K88 T107 1.2.1.- 0000166,0004365,0005829,0006006,0016491,0051287 A0A059ZTK9 401 MQRIAINGFGRIGRNVLRAWFESPKQFHFEIVAINDIADVHTLVHLFKYDSTHGRFNGKVDITIENEKIYLNIQSNQRLLKVEVLQQKQPELLPWASLKIDVVLECTGLFRSHADATRHLEAGAKRVIIGAAPFDHVDAAIVYGVNHADVKATDQIISSVSCTTQALVPLVKIIDDAFGIETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVMPKMEDRIDGYSIRVPTINVAAIDLTFIAQSPITVHHINELLIKASQTDYAEIMAVTDEPLVSSDFNHSPYSLIVDLTQTMVVGHQAKVFAWYDNEWGYANRLLDLCDSFKS 8zoz B 3.2 BS01 AMP B 1 F9 G10 R11 D36 I37 K88 L109 F9 G10 R11 D36 I37 K88 L109 1.2.1.- 0000166,0004365,0005829,0006006,0016491,0051287 A0A059ZTK9 401 MQRIAINGFGRIGRNVLRAWFESPKQFHFEIVAINDIADVHTLVHLFKYDSTHGRFNGKVDITIENEKIYLNIQSNQRLLKVEVLQQKQPELLPWASLKIDVVLECTGLFRSHADATRHLEAGAKRVIIGAAPFDHVDAAIVYGVNHADVKATDQIISSVSCTTQALVPLVKIIDDAFGIETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVMPKMEDRIDGYSIRVPTINVAAIDLTFIAQSPITVHHINELLIKASQTDYAEIMAVTDEPLVSSDFNHSPYSLIVDLTQTMVVGHQAKVFAWYDNEWGYANRLLDLCDSFKS 8zoz C 3.2 BS01 AMP C 1 G10 D36 I37 K88 G10 D36 I37 K88 1.2.1.- 0000166,0004365,0005829,0006006,0016491,0051287 A0A059ZTK9 401 MQRIAINGFGRIGRNVLRAWFESPKQFHFEIVAINDIADVHTLVHLFKYDSTHGRFNGKVDITIENEKIYLNIQSNQRLLKVEVLQQKQPELLPWASLKIDVVLECTGLFRSHADATRHLEAGAKRVIIGAAPFDHVDAAIVYGVNHADVKATDQIISSVSCTTQALVPLVKIIDDAFGIETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVMPKMEDRIDGYSIRVPTINVAAIDLTFIAQSPITVHHINELLIKASQTDYAEIMAVTDEPLVSSDFNHSPYSLIVDLTQTMVVGHQAKVFAWYDNEWGYANRLLDLCDSFKS 8zoz D 3.2 BS01 AMP D 1 N7 G8 D36 I37 K88 T107 N7 G8 D36 I37 K88 T107 1.2.1.- 0000166,0004365,0005829,0006006,0016491,0051287 A0A059ZTK9 401 MQRIAINGFGRIGRNVLRAWFESPKQFHFEIVAINDIADVHTLVHLFKYDSTHGRFNGKVDITIENEKIYLNIQSNQRLLKVEVLQQKQPELLPWASLKIDVVLECTGLFRSHADATRHLEAGAKRVIIGAAPFDHVDAAIVYGVNHADVKATDQIISSVSCTTQALVPLVKIIDDAFGIETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVMPKMEDRIDGYSIRVPTINVAAIDLTFIAQSPITVHHINELLIKASQTDYAEIMAVTDEPLVSSDFNHSPYSLIVDLTQTMVVGHQAKVFAWYDNEWGYANRLLDLCDSFKS 9asi A 2.79 BS06 AMP A 1 Y311 Y368 F528 Y305 Y362 F522 L0CEJ3 38989619 806 MDKINLVCGSLLADIGKIIYRGTSERAKHSKLGGDFIKSFEQFRNTELTDCIRYHHAQEITSVKSNKEKNSLFYITYIADNISSGMDRRKDLEEGAEGFNWDKKVALGSVFNVLNEKEKGRQNYSYPFVAEPLNFPTATQNQYTTSYYDGLITDMKTILQRLKPDKEHINSLLQMMESLWSYVPSSTDKNQLVDISLYDHSRTTAAIASAIYDYFQAENITDYQKELFDYNATEFYDKNAFLMMNFDMSGVQNFIYNISGSKALKSLRARSFYLDMLLEYISDNLLEKLELSRANILYVGGGHAYLLLANTNKTKAILSDFEHDLKTWFLDKFKIDLYVAMAYTEVSANDLMNHNGHYRDIYRRLSQKTSAKKANRYTAEEILNLNHQGTENARECRECKRSDLLIEEDDICEICDSLQKVSRDLTRENIFVIANEGVLDMPFGKKMSALSYSQADKLKKSNAEVQIYAKNISEIGQNLMTRIDMGDYTYRSDFHEMLEEVEVGINRLGVLRADVDNLGQAFINGIPDDYLSISRTATFSRAMSRFFKNYLNQLLAEKSYKINVIYAGGDDLFMIGAWQDILDFSIVLKQKFADFTQNKLSISAGIGMFREKYPVARMASLTGDLEDAAKDYKPDERAVQATKNAVTLFDATNVFSWDTLENDIFVKLDAITKNFEKLDETGKAFIYRLIDLLRGVNENQQINIARLAYTLSRMEEKIGKTFAQELYNWANADRKTLIMALEIYILKTRER 9b20 A 1.55 BS01 AMP A 1 F28 F29 R79 F22 F23 R73 3.6.1.13 0000166,0006753,0016787,0016818,0019144,0019693,0046872,0047631 A0A0H3GVQ7 301 QGITFSKNDVEIIARETLYRGFFSLDLYRFRHRLFNGGMSGEITREIFERGHAAVLLPFDPVRDEVVLVEQIRIAAYDTSESPWLLEMVAGMIEAGETVEDVARREALEEAGLEVGRTKPILSYLASPGGTSERLSILVGEVDASTAKEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHYHNLRNEWTK 9b20 A 1.55 BS03 AMP B 1 R51 E52 R45 E46 3.6.1.13 0000166,0006753,0016787,0016818,0019144,0019693,0046872,0047631 A0A0H3GVQ7 301 QGITFSKNDVEIIARETLYRGFFSLDLYRFRHRLFNGGMSGEITREIFERGHAAVLLPFDPVRDEVVLVEQIRIAAYDTSESPWLLEMVAGMIEAGETVEDVARREALEEAGLEVGRTKPILSYLASPGGTSERLSILVGEVDASTAKEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHYHNLRNEWTK 9b20 B 1.55 BS01 AMP A 1 R51 E52 R42 E43 3.6.1.13 0000166,0006753,0016787,0016818,0019144,0019693,0046872,0047631 A0A0H3GVQ7 301 TFSKNDVEIIARETLYRGFFSLDLYRFRHRLFNGGMSGEITREIFERGHAAVLLPFDPVRDEVVLVEQIRIAAYDTSESPWLLEMVAGMIEAGETVEDVARREALEEAGLEVGRTKPILSYLASPGGTSERLSILVGEVDASTAKGIHGLAEENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHYHNLRNEWT 9b20 B 1.55 BS02 AMP B 1 F28 F29 M98 E162 E164 F19 F20 M89 E153 E155 3.6.1.13 0000166,0006753,0016787,0016818,0019144,0019693,0046872,0047631 A0A0H3GVQ7 301 TFSKNDVEIIARETLYRGFFSLDLYRFRHRLFNGGMSGEITREIFERGHAAVLLPFDPVRDEVVLVEQIRIAAYDTSESPWLLEMVAGMIEAGETVEDVARREALEEAGLEVGRTKPILSYLASPGGTSERLSILVGEVDASTAKGIHGLAEENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHYHNLRNEWT 9b22 A 1.3 BS05 AMP B 1 R51 E52 R46 E47 3.6.1.13 0000166,0006753,0016787,0016818,0019144,0019693,0046872,0047631 A0A0H3GVQ7 304 QQGITFSKNDVEIIARETLYRGFFSLDLYRFRHRLFNGGMSGEITREIFERGHAAVLLPFDPVRDEVVLVEQIRIAAYDTSESPWLLEMVAGMIEAGETVEDVARREALEEAGLEVGRTKPILSYLASPGGTSERLSILVGEVDASTAKGIHGLENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHYHNLRNEWT 9b22 B 1.3 BS05 AMP B 1 F28 F29 F23 F24 3.6.1.13 0000166,0006753,0016787,0016818,0019144,0019693,0046872,0047631 A0A0H3GVQ7 304 QQGITFSKNDVEIIARETLYRGFFSLDLYRFRHRLFNGGMSGEITREIFERGHAAVLLPFDPVRDEVVLVEQIRIAAYDTSESPWLLEMVAGMIEAGETVEDVARREALEEAGLEVGRTKPILSYLASPGGTSERLSILVGEVDASTAKGIHGLAEENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHYHNLRNEWTK 9b5h A 2.69 BS02 AMP B 1 D463 M464 K487 R512 V513 L536 D537 D450 M451 K474 R499 V500 L523 D524 6.2.1.45 0000287,0004839,0005515,0005524,0005634,0005737,0005829,0006511,0006974,0016567,0016874,0016887 O94609 39143218 101 TIDEGLYSRQLYVLGHEAMKQMSQSNVLIIGCKGLGVEIAKNVCLAGVKSVTLYDPQPTRIEDLSSQYFLTEDDIGVPRAKVTVSKLAELNQYVPVSVVDELSTEYLKNFKCVVVTETSLTKQLEINDFTHKNHIAYIAADSRGLFGSIFCDFGENFICTDTDGNEPLTGMIASITDDGVVTMLEETRHGLENGDFVKFTEVKGMPGLNDGTPRKVEVKGPYTFSIGSVKDLGSAGYNGVFTQVKVPTKISFKSLRESLKDPEYVYPDFGKMMRPPQYHIAFQALSAFADAHEGSLPRPRNDIDAAEFFEFCKKIASTLQFDVELDEKLIKEISYQARGDLVAMSAFLGGAVAQEVLKATTSKFYPLKQYFYFDSLESLPSSVTISEETCKPRGCRYDGQIAVFGSEFQEKIASLSTFLVGAGAIGCEMLKNWAMMGVATGESGHISVTDMDSIEKSNLNRQFLFRPRDVGKLKSECASTAVSIMNPSLTGKITSYQERVGPESEGIFGDEFFEKLSLVTNALDNVEARMYVDRRCVFFEKPLLESGTLGTKGNTQVVVPHLTESYGSSQDPPEKSFPICTLKNFPNRIEHTIAWARDLFEGLFKQPIDNVNMYLSSPNFLETSLKTSSNPREVLENIRDYLVTEKPLSFEECIMWARLQFDKFFNNNIQQLLFNFPKDSVTSTGQPFWSGPKRAPTPLSFDIHNREHFDFIVAAASLYAFNYGLKSETDPAIYERVLAGYNPPPFAPKSGIANKDKQELKSIADSLPPPSSLVGFRLTPAEFEKDDDSNHHIDFITAASNLRAMNYDITPADRFKTKFVAGKIVPAMCTSTAVVSGLVCLELVKLVDGKKKIEEYKNGFFNLAIGLFTFSDPIASPKMKVNGKEIDKIWDRYNLPDCTLQELIDYFQKEEGLEVTMLSSGVSLLYANFQPPKKLAERLPLKISELVEQITKKKLEPFRKHLVLEICCDDANGEDVEVPFICIKL 9b5i A 2.7 BS02 AMP B 1 D463 M464 R474 K487 R512 V513 L536 D537 N538 D450 M451 R461 K474 R499 V500 L523 D524 N525 6.2.1.45 0000287,0004839,0005515,0005524,0005634,0005737,0005829,0006511,0006974,0016567,0016874,0016887 O94609 39143218 101 TIDEGLYSRQLYVLGHEAMKQMSQSNVLIIGCKGLGVEIAKNVCLAGVKSVTLYDPQPTRIEDLSSQYFLTEDDIGVPRAKVTVSKLAELNQYVPVSVVDELSTEYLKNFKCVVVTETSLTKQLEINDFTHKNHIAYIAADSRGLFGSIFCDFGENFICTDTDGNEPLTGMIASITDDGVVTMLEETRHGLENGDFVKFTEVKGMPGLNDGTPRKVEVKGPYTFSIGSVKDLGSAGYNGVFTQVKVPTKISFKSLRESLKDPEYVYPDFGKMMRPPQYHIAFQALSAFADAHEGSLPRPRNDIDAAEFFEFCKKIASTLQFDVELDEKLIKEISYQARGDLVAMSAFLGGAVAQEVLKATTSKFYPLKQYFYFDSLESLPSSVTISEETCKPRGCRYDGQIAVFGSEFQEKIASLSTFLVGAGAIGCEMLKNWAMMGVATGESGHISVTDMDSIEKSNLNRQFLFRPRDVGKLKSECASTAVSIMNPSLTGKITSYQERVGPESEGIFGDEFFEKLSLVTNALDNVEARMYVDRRCVFFEKPLLESGTLGTKGNTQVVVPHLTESYGSSQDPPEKSFPICTLKNFPNRIEHTIAWARDLFEGLFKQPIDNVNMYLSSPNFLETSLKTSSNPREVLENIRDYLVTEKPLSFEECIMWARLQFDKFFNNNIQQLLFNFPKDSVTSTGQPFWSGPKRAPTPLSFDIHNREHFDFIVAAASLYAFNYGLKSETDPAIYERVLAGYNPPPFAPKSGIANKDKQELKSIADSLPPPSSLVGFRLTPAEFEKDDDSNHHIDFITAASNLRAMNYDITPADRFKTKFVAGKIVPAMCTSTAVVSGLVCLELVKLVDGKKKIEEYKNGFFNLAIGLFTFSDPIASPKMKVNGKEIDKIWDRYNLPDCTLQELIDYFQKEEGLEVTMLSSGVSLLYANFQPPKKLAERLPLKISELVEQITKKKLEPFRKHLVLEICCDDANGEDVEVPFICIKL 9b5j A 2.86 BS01 AMP B 1 D463 M464 D465 R474 K487 R512 V513 A535 L536 D537 N538 D450 M451 D452 R461 K474 R499 V500 A522 L523 D524 N525 6.2.1.45 0000287,0004839,0005515,0005524,0005634,0005737,0005829,0006511,0006974,0016567,0016874,0016887 O94609 39143218 101 TIDEGLYSRQLYVLGHEAMKQMSQSNVLIIGCKGLGVEIAKNVCLAGVKSVTLYDPQPTRIEDLSSQYFLTEDDIGVPRAKVTVSKLAELNQYVPVSVVDELSTEYLKNFKCVVVTETSLTKQLEINDFTHKNHIAYIAADSRGLFGSIFCDFGENFICTDTDGNEPLTGMIASITDDGVVTMLEETRHGLENGDFVKFTEVKGMPGLNDGTPRKVEVKGPYTFSIGSVKDLGSAGYNGVFTQVKVPTKISFKSLRESLKDPEYVYPDFGKMMRPPQYHIAFQALSAFADAHEGSLPRPRNDIDAAEFFEFCKKIASTLQFDVELDEKLIKEISYQARGDLVAMSAFLGGAVAQEVLKATTSKFYPLKQYFYFDSLESLPSSVTISEETCKPRGCRYDGQIAVFGSEFQEKIASLSTFLVGAGAIGCEMLKNWAMMGVATGESGHISVTDMDSIEKSNLNRQFLFRPRDVGKLKSECASTAVSIMNPSLTGKITSYQERVGPESEGIFGDEFFEKLSLVTNALDNVEARMYVDRRCVFFEKPLLESGTLGTKGNTQVVVPHLTESYGSSQDPPEKSFPICTLKNFPNRIEHTIAWARDLFEGLFKQPIDNVNMYLSSPNFLETSLKTSSNPREVLENIRDYLVTEKPLSFEECIMWARLQFDKFFNNNIQQLLFNFPKDSVTSTGQPFWSGPKRAPTPLSFDIHNREHFDFIVAAASLYAFNYGLKSETDPAIYERVLAGYNPPPFAPKSGIANKDKQELKSIADSLPPPSSLVGFRLTPAEFEKDDDSNHHIDFITAASNLRAMNYDITPADRFKTKFVAGKIVPAMCTSTAVVSGLVCLELVKLVDGKKKIEEYKNGFFNLAIGLFTFSDPIASPKMKVNGKEIDKIWDRYNLPDCTLQELIDYFQKEEGLEVTMLSSGVSLLYANFQPPKKLAERLPLKISELVEQITKKKLEPFRKHLVLEICCDDANGEDVEVPFICIKL 9b5l A 3.3 BS01 AMP B 1 D463 M464 D465 K487 V513 L536 D537 N538 D450 M451 D452 K474 V500 L523 D524 N525 6.2.1.45 0000287,0004839,0005515,0005524,0005634,0005737,0005829,0006511,0006974,0016567,0016874,0016887 O94609 39143218 101 TIDEGLYSRQLYVLGHEAMKQMSQSNVLIIGCKGLGVEIAKNVCLAGVKSVTLYDPQPTRIEDLSSQYFLTEDDIGVPRAKVTVSKLAELNQYVPVSVVDELSTEYLKNFKCVVVTETSLTKQLEINDFTHKNHIAYIAADSRGLFGSIFCDFGENFICTDTDGNEPLTGMIASITDDGVVTMLEETRHGLENGDFVKFTEVKGMPGLNDGTPRKVEVKGPYTFSIGSVKDLGSAGYNGVFTQVKVPTKISFKSLRESLKDPEYVYPDFGKMMRPPQYHIAFQALSAFADAHEGSLPRPRNDIDAAEFFEFCKKIASTLQFDVELDEKLIKEISYQARGDLVAMSAFLGGAVAQEVLKATTSKFYPLKQYFYFDSLESLPSSVTISEETCKPRGCRYDGQIAVFGSEFQEKIASLSTFLVGAGAIGCEMLKNWAMMGVATGESGHISVTDMDSIEKSNLNRQFLFRPRDVGKLKSECASTAVSIMNPSLTGKITSYQERVGPESEGIFGDEFFEKLSLVTNALDNVEARMYVDRRCVFFEKPLLESGTLGTKGNTQVVVPHLTESYGSSQDPPEKSFPICTLKNFPNRIEHTIAWARDLFEGLFKQPIDNVNMYLSSPNFLETSLKTSSNPREVLENIRDYLVTEKPLSFEECIMWARLQFDKFFNNNIQQLLFNFPKDSVTSTGQPFWSGPKRAPTPLSFDIHNREHFDFIVAAASLYAFNYGLKSETDPAIYERVLAGYNPPPFAPKSGIANKDKQELKSIADSLPPPSSLVGFRLTPAEFEKDDDSNHHIDFITAASNLRAMNYDITPADRFKTKFVAGKIVPAMCTSTAVVSGLVCLELVKLVDGKKKIEEYKNGFFNLAIGLFTFSDPIASPKMKVNGKEIDKIWDRYNLPDCTLQELIDYFQKEEGLEVTMLSSGVSLLYANFQPPKKLAERLPLKISELVEQITKKKLEPFRKHLVLEICCDDANGEDVEVPFICIKL 9bs3 A 2.69 BS04 AMP A 1 E566 Y567 K568 Y569 E621 F660 E720 M723 K725 K744 K746 E299 Y300 K301 Y302 E354 F393 E453 M456 K458 K477 K479 P18858 39159820 1001 DPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQ 9bs3 E 2.69 BS04 AMP E 1 K568 Y569 E621 F660 E720 M723 K725 K744 K746 K308 Y309 E361 F400 E460 M463 K465 K484 K486 P18858 39159820 1001 LDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKK 9bs4 A 2.4 BS04 AMP A 1 E566 Y567 K568 Y569 E621 F660 E720 M723 K725 K744 K746 E298 Y299 K300 Y301 E353 F392 E452 M455 K457 K476 K478 P18858 39159820 1001 DPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQ 9bs4 E 2.4 BS04 AMP E 1 E566 K568 Y569 E621 F660 E720 M723 K725 K744 E306 K308 Y309 E361 F400 E460 M463 K465 K484 P18858 39159820 1001 LDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKD 9d8s A 2.12 BS01 AMP A 1 V90 A103 K105 Y155 L205 D219 V22 A35 K37 Y84 L134 D148 A3FQ16 601 MGTFAERYNIVCMLGKGSFGEVLKCKDRITQQEYAVKVINKASAKTSTILREVELLKKLDHPNIMKLFEILEDSSSFYIVGELYTGGELFDEIIKRKRFSEHDAARIIKQVFSGITYMHKHNIVHRDLKPENILLESKEKDCDIKIIDFGLSTCFQQNTKMKDRIGTAYYIAPEVLRGTYDEKCDVWSAGVILYILLSGTPPFYGKNEYDILKRVETGKYAFDLPQWRTISDDAKDLIRKMLTFHPSLRITATQCLEHPWIQKYSSETPTISDLPSLESAMTNIRQFQAEKKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQGSTIEDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFFNEFVEMLQ 9emb A 2.98 BS01 AMP A 1 F407 R409 H430 D431 D449 A450 I471 R496 F394 R396 H417 D418 D436 A437 I458 R483 ? 0000166,0005515,0005886,0006813,0006885,0009636,0015297,0015503,0015643,0016020,0019899,0042542,0042803,0051453,0051454,0051595,0071805,1903103 P03819 601 MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQNIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAM 9emb B 2.98 BS01 AMP B 1 F407 R409 H430 D449 A450 D472 R496 F393 R395 H416 D435 A436 D458 R482 ? 0000166,0005515,0005886,0006813,0006885,0009636,0015297,0015503,0015643,0016020,0019899,0042542,0042803,0051453,0051454,0051595,0071805,1903103 P03819 601 MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQNIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAM 9ij6 A 2.4 BS01 AMP A 1 G10 D36 I37 K88 T107 G10 D36 I37 K88 T107 0000166,0004365,0005829,0006006,0016491,0051287 A0A059ZTK9 401 MQRIAINGFGRIGRNVLRAWFESPKQFHFEIVAINDIADVHTLVHLFKYDSTHGRFNGKVDITIENEKIYLNIQSNQRLLKVEVLQQKQPELLPWASLKIDVVLECTGLFRSHADATRHLEAGAKRVIIGAAPFDHVDAAIVYGVNHADVKATDQIISSVSCTTQALVPLVKIIDDAFGIETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVMPKMEDRIDGYSIRVPTINVAAIDLTFIAQSPITVHHINELLIKASQTDYAEIMAVTDEPLVSSDFNHSPYSLIVDLTQTMVVGHQAKVFAWYDNEWGYANRLLDLCDSFKS 9ij6 B 2.4 BS01 AMP B 1 G10 R11 D36 K88 T107 G10 R11 D36 K88 T107 0000166,0004365,0005829,0006006,0016491,0051287 A0A059ZTK9 401 MQRIAINGFGRIGRNVLRAWFESPKQFHFEIVAINDIADVHTLVHLFKYDSTHGRFNGKVDITIENEKIYLNIQSNQRLLKVEVLQQKQPELLPWASLKIDVVLECTGLFRSHADATRHLEAGAKRVIIGAAPFDHVDAAIVYGVNHADVKATDQIISSVSCTTQALVPLVKIIDDAFGIETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVMPKMEDRIDGYSIRVPTINVAAIDLTFIAQSPITVHHINELLIKASQTDYAEIMAVTDEPLVSSDFNHSPYSLIVDLTQTMVVGHQAKVFAWYDNEWGYANRLLDLCDSFKS 9ij6 C 2.4 BS01 AMP C 1 G10 R11 D36 I37 K88 T107 G10 R11 D36 I37 K88 T107 0000166,0004365,0005829,0006006,0016491,0051287 A0A059ZTK9 401 MQRIAINGFGRIGRNVLRAWFESPKQFHFEIVAINDIADVHTLVHLFKYDSTHGRFNGKVDITIENEKIYLNIQSNQRLLKVEVLQQKQPELLPWASLKIDVVLECTGLFRSHADATRHLEAGAKRVIIGAAPFDHVDAAIVYGVNHADVKATDQIISSVSCTTQALVPLVKIIDDAFGIETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVMPKMEDRIDGYSIRVPTINVAAIDLTFIAQSPITVHHINELLIKASQTDYAEIMAVTDEPLVSSDFNHSPYSLIVDLTQTMVVGHQAKVFAWYDNEWGYANRLLDLCDSFKS 9ij6 D 2.4 BS01 AMP D 1 G10 D36 I37 K88 T107 G10 D36 I37 K88 T107 0000166,0004365,0005829,0006006,0016491,0051287 A0A059ZTK9 401 MQRIAINGFGRIGRNVLRAWFESPKQFHFEIVAINDIADVHTLVHLFKYDSTHGRFNGKVDITIENEKIYLNIQSNQRLLKVEVLQQKQPELLPWASLKIDVVLECTGLFRSHADATRHLEAGAKRVIIGAAPFDHVDAAIVYGVNHADVKATDQIISSVSCTTQALVPLVKIIDDAFGIETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVMPKMEDRIDGYSIRVPTINVAAIDLTFIAQSPITVHHINELLIKASQTDYAEIMAVTDEPLVSSDFNHSPYSLIVDLTQTMVVGHQAKVFAWYDNEWGYANRLLDLCDSFKS