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BioLiP
Download all results in tab-seperated text for 242 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1d0k:A (2.02) BS05 ALA 4.2.2.n1 GO:0005509 ... P41052 10684641
    2 1e8k:A (1.9) BS01 ALA 5.2.1.8 GO:0000413 ... P52011 11180378
    3 1kl6:A (1.8) BS06 ALA 3.4.24.27 GO:0004222 ... P00800 N/A
    4 1tkk:A (2.1) BS02 ALA 5.1.1.20 GO:0016853 ... O34508 15301535
    5 1tkk:B (2.1) BS02 ALA 5.1.1.20 GO:0016853 ... O34508 15301535
    6 1tkk:C (2.1) BS02 ALA 5.1.1.20 GO:0016853 ... O34508 15301535
    7 1tkk:D (2.1) BS02 ALA 5.1.1.20 GO:0016853 ... O34508 15301535
    8 1tkk:E (2.1) BS02 ALA 5.1.1.20 GO:0016853 ... O34508 15301535
    9 1tkk:F (2.1) BS02 ALA 5.1.1.20 GO:0016853 ... O34508 15301535
    10 1tkk:G (2.1) BS02 ALA 5.1.1.20 GO:0016853 ... O34508 15301535
    11 1tkk:H (2.1) BS02 ALA 5.1.1.20 GO:0016853 ... O34508 15301535
    12 1xrm:A (2.7) BS02 ALA 3.4.11.5 GO:0004177 ... P96084 15994304
    13 1xrn:A (2.8) BS01 ALA 3.4.11.5 GO:0004177 ... P96084 15994304
    14 1yfs:A (2.08) BS01 ALA 6.1.1.7 GO:0000166 ... O67323 15657145
    15 1yfs:B (2.08) BS01 ALA 6.1.1.7 GO:0000166 ... O67323 15657145
    16 2bd3:A (1.6) BS04 ALA 3.4.21.36 GO:0004252 ... P00772 16754679
    17 2bda:A (1.8) BS02 ALA 3.4.21.36 GO:0004252 ... P00772 16754679
    18 2bdb:A (1.7) BS02 ALA 3.4.21.36 GO:0004252 ... P00772 16754679
    19 2cfe:A (1.5) BS01 ALA 5.2.1.8 GO:0000413 ... O93970 16483252
    20 2cyh:A (1.64) BS01 ALA 5.2.1.8 GO:0000413 ... P62937 8652512
    21 2eit:A (1.65) BS01 ALA 1.2.1.88 GO:0000166 ... Q5SI02 N/A
    22 2eit:B (1.65) BS01 ALA 1.2.1.88 GO:0000166 ... Q5SI02 N/A
    23 2ejd:A (1.85) BS01 ALA 1.2.1.88 GO:0000166 ... Q5SI02 N/A
    24 2ejd:B (1.85) BS01 ALA 1.2.1.88 GO:0000166 ... Q5SI02 N/A
    25 2g50:A (1.65) BS02 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P11974 16634623
    26 2g50:B (1.65) BS02 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P11974 16634623
    27 2g50:C (1.65) BS02 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P11974 16634623
    28 2g50:D (1.65) BS02 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P11974 16634623
    29 2g50:E (1.65) BS02 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P11974 16634623
    30 2g50:F (1.65) BS02 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P11974 16634623
    31 2g50:G (1.65) BS02 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P11974 16634623
    32 2g50:H (1.65) BS02 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P11974 16634623
    33 2huu:A (2.1) BS01 ALA 2.6.1.44 GO:0004760 ... Q3LSM4 16990263
    34 2huu:B (2.1) BS01 ALA 2.6.1.44 GO:0004760 ... Q3LSM4 16990263
    35 2ixv:A (1.96) BS02 ALA 3.2.1.17 GO:0003796 ... P15057 17581815
    36 2jb1:A (1.55) BS01 ALA 1.4.3.2 GO:0000166 ... Q8VPD4 17234209
    37 2jb1:B (1.55) BS01 ALA 1.4.3.2 GO:0000166 ... Q8VPD4 17234209
    38 2qei:A (1.85) BS03 ALA ? GO:0005886 ... O67854 17687333
    39 2qer:A (2.17) BS01 ALA 5.2.1.8 GO:0000413 ... A3FQ68 N/A
    40 2wts:A (1.3) BS01 ALA 2.3.2.12 N/A A0A0H2UNQ9 19810750
    41 2z9x:A (1.94) BS01 ALA 2.6.1.30 GO:0008483 ... Q988B8 17989071
    42 2z9x:B (1.94) BS01 ALA 2.6.1.30 GO:0008483 ... Q988B8 17989071
    43 3c8c:A (1.5) BS02 ALA ? N/A Q9KL26 N/A
    44 3c8c:B (1.5) BS02 ALA ? N/A Q9KL26 N/A
    45 3deq:A (2.1) BS02 ALA 5.1.1.20 GO:0016853 ... Q9WXM1 19000819
    46 3deq:B (2.1) BS02 ALA 5.1.1.20 GO:0016853 ... Q9WXM1 19000819
    47 3deq:C (2.1) BS02 ALA 5.1.1.20 GO:0016853 ... Q9WXM1 19000819
    48 3deq:D (2.1) BS02 ALA 5.1.1.20 GO:0016853 ... Q9WXM1 19000819
    49 3der:A (1.9) BS02 ALA 5.1.1.20 GO:0016853 ... Q9WXM1 19000819
    50 3der:B (1.9) BS02 ALA 5.1.1.20 GO:0016853 ... Q9WXM1 19000819
    51 3der:C (1.9) BS02 ALA 5.1.1.20 GO:0016853 ... Q9WXM1 19000819
    52 3der:D (1.9) BS02 ALA 5.1.1.20 GO:0016853 ... Q9WXM1 19000819
    53 3des:A (2.3) BS02 ALA 5.1.1.20 GO:0016853 ... Q9WXM1 19000819
    54 3des:B (2.3) BS02 ALA 5.1.1.20 GO:0016853 ... Q9WXM1 19000819
    55 3des:C (2.3) BS02 ALA 5.1.1.20 GO:0016853 ... Q9WXM1 19000819
    56 3des:D (2.3) BS02 ALA 5.1.1.20 GO:0016853 ... Q9WXM1 19000819
    57 3f48:A (1.9) BS03 ALA ? GO:0005886 ... O67854 19074341 MOAD: Kd=512nM
    PDBbind: -logKd/Ki=6.29, Kd=512nM
    58 3h41:A (1.79) BS01 ALA 3.4.14.13 GO:0006508 ... Q736M3 20944232
    59 3iji:A (1.6) BS01 ALA 5.1.1.20 GO:0016855 ... Q8A861 22392983
    60 3iji:B (1.6) BS01 ALA 5.1.1.20 GO:0016855 ... Q8A861 22392983
    61 3ijq:A (2.0) BS01 ALA 5.1.1.20 GO:0016855 ... Q8A861 22392983
    62 3ijq:B (2.0) BS01 ALA 5.1.1.20 GO:0016855 ... Q8A861 22392983
    63 3ip5:A (1.35) BS01 ALA ? GO:0006865 ... Q7CX36 20630861 MOAD: Kd=0.6uM
    PDBbind: -logKd/Ki=6.22, Kd=0.6uM
    64 3ipa:A (1.55) BS01 ALA ? GO:0006865 ... Q7CX36 20630861 PDBbind: -logKd/Ki=6.22, Kd=0.6uM
    65 3nw3:D (2.5) BS02 ALA ? GO:0001818 ... Q9GK12 21784863
    66 3q4d:A (3.0) BS03 ALA 5.1.1.- GO:0000287 ... Q11T61 22392983
    67 3q4d:B (3.0) BS03 ALA 5.1.1.- GO:0000287 ... Q11T61 22392983
    68 3q4d:C (3.0) BS03 ALA 5.1.1.- GO:0000287 ... Q11T61 22392983
    69 3q4d:D (3.0) BS03 ALA 5.1.1.- GO:0000287 ... Q11T61 22392983
    70 3q4d:E (3.0) BS03 ALA 5.1.1.- GO:0000287 ... Q11T61 22392983
    71 3q4d:F (3.0) BS03 ALA 5.1.1.- GO:0000287 ... Q11T61 22392983
    72 3q4d:G (3.0) BS03 ALA 5.1.1.- GO:0000287 ... Q11T61 22392983
    73 3q4d:H (3.0) BS03 ALA 5.1.1.- GO:0000287 ... Q11T61 22392983
    74 3q4d:I (3.0) BS03 ALA 5.1.1.- GO:0000287 ... Q11T61 22392983
    75 3r1z:A (1.9) BS01 ALA 5.1.1.- GO:0000287 ... B0TZW0 22392983
    76 3r1z:B (1.9) BS01 ALA 5.1.1.- GO:0000287 ... B0TZW0 22392983
    77 3tu0:A (2.994) BS02 ALA ? GO:0005886 ... O67854 22230955
    78 3wo0:A (2.0) BS03 ALA 6.3.2.49 GO:0003824 ... P39641 24702628
    79 3wo1:A (2.3) BS03 ALA 6.3.2.49 GO:0003824 ... P39641 24702628
    80 4cvm:A (2.06) BS01 ALA 6.3.2.10 GO:0005524 ... Q9HVZ7 N/A
    81 4d2c:A (2.47) BS06 ALA ? GO:0005886 ... Q5M4H8 24916388
    82 4fkh:A (2.05) BS01 ALA 3.4.11.2 GO:0001525 ... P15145 23071329
    83 4g4w:A (1.9) BS01 ALA N/A GO:0009279 ... N/A N/A
    84 4g4y:A (1.7) BS01 ALA ? GO:0016020 ... Q6RYW5 N/A
    85 4g4y:B (1.7) BS01 ALA ? GO:0016020 ... Q6RYW5 N/A
    86 4g4y:C (1.7) BS01 ALA ? GO:0016020 ... Q6RYW5 N/A
    87 4g4y:D (1.7) BS01 ALA ? GO:0016020 ... Q6RYW5 N/A
    88 4g4y:E (1.7) BS01 ALA ? GO:0016020 ... Q6RYW5 N/A
    89 4g4y:F (1.7) BS01 ALA ? GO:0016020 ... Q6RYW5 N/A
    90 4g4y:G (1.7) BS01 ALA ? GO:0016020 ... Q6RYW5 N/A
    91 4g4y:H (1.7) BS01 ALA ? GO:0016020 ... Q6RYW5 N/A
    92 4gfi:A (1.9) BS01 ALA 5.1.1.- GO:0016853 ... A9CIT6 N/A
    93 4gfi:B (1.9) BS01 ALA 5.1.1.- GO:0016853 ... A9CIT6 N/A
    94 4gfi:C (1.9) BS01 ALA 5.1.1.- GO:0016853 ... A9CIT6 N/A
    95 4gfi:D (1.9) BS01 ALA 5.1.1.- GO:0016853 ... A9CIT6 N/A
    96 4guk:B (1.75) BS04 ALA ? GO:0005245 ... P62166 N/A
    97 4id9:A (1.6) BS01 ALA ? GO:0000166 ... A9CL58 N/A
    98 4io5:A (1.721) BS01 ALA ? GO:0015276 ... E9P5T5 23434404 MOAD: Kd=9uM
    PDBbind: -logKd/Ki=5.03, Kd=9.27uM
    99 4io5:B (1.721) BS01 ALA ? GO:0015276 ... E9P5T5 23434404 MOAD: Kd=9uM
    100 4lwx:A (1.78) BS01 ALA 3.2.2.22 GO:0000166 ... D9J2T9 N/A
    101 4nqr:A (1.09) BS01 ALA ? GO:0046872 ... Q3MFZ5 N/A
    102 4nqr:B (1.09) BS01 ALA ? GO:0046872 ... Q3MFZ5 N/A
    103 4nt8:A (2.2) BS02 ALA 3.5.1.88 GO:0042586 ... Q5H3Z2 N/A
    104 4qfl:A (1.749) BS01 ALA ? GO:0015833 ... A7Y7W1 25605306
    105 4qfl:B (1.749) BS01 ALA ? GO:0015833 ... A7Y7W1 25605306
    106 4tph:A (3.155) BS01 ALA ? GO:0005886 ... Q8EHE6 25064511
    107 4wcx:A (1.59) BS04 ALA ? GO:0003824 ... D3T7F1 25605932
    108 4whx:A (2.05) BS01 ALA N/A GO:0003824 ... N/A N/A
    109 4whx:C (2.05) BS01 ALA N/A GO:0003824 ... N/A N/A
    110 4whx:D (2.05) BS01 ALA N/A GO:0003824 ... N/A N/A
    111 4whx:E (2.05) BS01 ALA N/A GO:0003824 ... N/A N/A
    112 4xl8:B (1.65) BS02 ALA ? GO:0007155 ... A0MK70 25674795
    113 4xmu:A (2.91) BS02 ALA 3.4.11.2 GO:0004177 ... P04825 N/A
    114 4xn8:A (1.89) BS02 ALA 3.4.11.2 GO:0004177 ... P04825 N/A
    115 4y2w:A (2.7) BS02 ALA 5.1.1.1 GO:0003824 ... Q8RAK6 26218070
    116 4ykj:A (1.401) BS01 ALA ? GO:0015276 ... A0A0R4I973 26460032 MOAD: Ki=37uM
    PDBbind: -logKd/Ki=4.43, Ki=37uM
    117 4ykj:B (1.401) BS01 ALA ? GO:0015276 ... A0A0R4I973 26460032 MOAD: Ki=37uM
    118 5a3b:A (1.9) BS02 ALA N/A N/A N/A 26166706
    119 5b87:A (2.28) BS02 ALA 2.8.1.7 GO:0006534 ... B6YT87 28536498
    120 5b87:B (2.28) BS03 ALA 2.8.1.7 GO:0006534 ... B6YT87 28536498
    121 5b89:A (1.5) BS01 ALA 2.8.1.7 GO:0006534 ... B6YT87 28536498
    122 5b89:B (1.5) BS03 ALA 2.8.1.7 GO:0006534 ... B6YT87 28536498
    123 5cpd:A (2.2) BS02 ALA 3.5.1.88 GO:0042586 ... Q5H3Z2 N/A
    124 5d58:A (2.4) BS01 ALA ? GO:0005886 ... Q5M4H8 26894538
    125 5d59:A (2.4) BS01 ALA ? GO:0005886 ... Q5M4H8 26894538
    126 5inr:A (1.652) BS01 ALA N/A GO:0006508 ... N/A N/A
    127 5inr:B (1.652) BS01 ALA N/A GO:0006508 ... N/A N/A
    128 5inr:C (1.652) BS01 ALA N/A GO:0006508 ... N/A N/A
    129 5inr:D (1.652) BS01 ALA N/A GO:0006508 ... N/A N/A
    130 5inr:E (1.652) BS01 ALA N/A GO:0006508 ... N/A N/A
    131 5inx:A (1.681) BS02 ALA N/A GO:0006508 ... N/A N/A
    132 5inx:B (1.681) BS02 ALA N/A GO:0006508 ... N/A N/A
    133 5inx:C (1.681) BS02 ALA N/A GO:0006508 ... N/A N/A
    134 5inx:D (1.681) BS02 ALA N/A GO:0006508 ... N/A N/A
    135 5inx:E (1.681) BS02 ALA N/A GO:0006508 ... N/A N/A
    136 5j8q:A (1.702) BS02 ALA 2.8.1.7 GO:0003824 ... O32164 27382962
    137 5oqt:A (2.86) BS02 ALA ? GO:0003333 ... Q5L1G5 29416041
    138 5oxk:A (2.38) BS14 ALA ? GO:0005886 ... Q5M4H8 29429879 PDBbind: -logKd/Ki=2.17, Kd=6.82mM
    139 5oxl:A (2.66) BS09 ALA ? GO:0005886 ... Q5M4H8 29429879 PDBbind: -logKd/Ki=3.25, Kd=0.56mM
    140 5oxn:A (2.196) BS14 ALA ? GO:0005886 ... Q5M4H8 29429879 PDBbind: -logKd/Ki=1.96, Kd=10.95mM
    141 5pgm:E (2.12) BS01 ALA 5.4.2.11 GO:0003824 ... P00950 10064712
    142 5ucr:A (2.25) BS02 ALA 6.3.2.1 GO:0003824 ... B4RKE7 N/A
    143 5ucr:B (2.25) BS02 ALA 6.3.2.1 GO:0003824 ... B4RKE7 N/A
    144 5x2n:A (2.2) BS01 ALA ? GO:0004930 ... A0A173M0G2 28534491
    145 5x2n:B (2.2) BS01 ALA ? GO:0004930 ... A0A173M094 28534491
    146 5x2n:C (2.2) BS01 ALA ? GO:0004930 ... A0A173M0G2 28534491
    147 5x2n:D (2.2) BS01 ALA ? GO:0004930 ... A0A173M094 28534491
    148 5z57:A (6.5) BS07 ALA ? GO:0000244 ... Q6P2Q9 29360106
    149 6cse:M (3.24) BS02 ALA ? GO:0003333 ... Q6LX42 30659158 PDBbind: -logKd/Ki=5.60, Kd=2.5uM
    150 6f0a:A (2.26) BS02 ALA 1.13.11.52 GO:0002376 ... P14902 29240291
    151 6f0a:C (2.26) BS02 ALA 1.13.11.52 GO:0002376 ... P14902 29240291
    152 6gcn:B (2.949) BS03 ALA 3.4.24.- GO:0004176 ... O67077 30118817
    153 6gg3:A (3.72) BS01 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P14618 29748232 PDBbind: -logKd/Ki=4.21, Ki=62uM
    154 6gg3:C (3.72) BS01 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P14618 29748232
    155 6gg3:D (3.72) BS01 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P14618 29748232
    156 6gg3:E (3.72) BS01 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P14618 29748232
    157 6gg3:F (3.72) BS01 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P14618 29748232
    158 6gg3:G (3.72) BS01 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P14618 29748232
    159 6gg3:H (3.72) BS01 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P14618 29748232
    160 6gg3:I (3.72) BS01 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P14618 29748232
    161 6gg3:J (3.72) BS01 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P14618 29748232
    162 6gg3:K (3.72) BS01 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P14618 29748232
    163 6gg3:L (3.72) BS01 ALA 2.7.10.2
    2.7.11.1
    2.7.1.40
    GO:0000287 ... P14618 29748232
    164 6iop:B (2.3) BS01 ALA ? N/A Q9KQ43 30745373 MOAD: Kd=5.1uM
    165 6pxy:A (2.0) BS01 ALA ? N/A Q3K7T6 31909676
    166 6pyi:A (1.95) BS01 ALA ? N/A Q3K7T6 31909676
    167 6u6c:E (2.402) BS01 ALA 4.2.1.20 GO:0000162 ... P9WFY1 31930594
    168 6w3y:A (1.32) BS01 ALA ? N/A Q0P864 32403336
    169 6w3y:B (1.32) BS01 ALA ? N/A Q0P864 32403336
    170 6wjm:A (1.0) BS01 ALA 3.5.2.6 GO:0008800 ... E1QJV5 N/A
    171 6x7l:A (1.77) BS01 ALA ? GO:0016417 ... Q8GGP1 33482062
    172 6xsj:B (1.4) BS02 ALA 3.2.1.1 GO:0004556 ... P0C1B3 33814275
    173 7fsh:D (2.11) BS03 ALA ? N/A O00560 N/A
    174 7fsj:D (1.97) BS01 ALA ? N/A O00560 N/A
    175 7fsk:D (2.4) BS01 ALA ? N/A O00560 N/A
    176 7fsl:D (2.38) BS01 ALA ? N/A O00560 N/A
    177 7fsm:D (2.1) BS01 ALA ? N/A O00560 N/A
    178 7fsn:D (2.4) BS01 ALA ? N/A O00560 N/A
    179 7fsp:D (1.86) BS02 ALA ? N/A O00560 N/A
    180 7fsq:D (2.07) BS01 ALA ? N/A O00560 N/A
    181 7fsr:D (2.29) BS02 ALA ? N/A O00560 N/A
    182 7fss:D (2.11) BS01 ALA ? N/A O00560 N/A
    183 7fst:D (1.98) BS01 ALA ? N/A O00560 N/A
    184 7fsu:D (1.97) BS02 ALA ? N/A O00560 N/A
    185 7fsv:D (2.25) BS02 ALA ? N/A O00560 N/A
    186 7fsw:D (2.14) BS01 ALA ? N/A O00560 N/A
    187 7fsx:D (1.91) BS01 ALA ? N/A O00560 N/A
    188 7fsy:D (2.8) BS01 ALA ? N/A O00560 N/A
    189 7ft1:D (2.11) BS02 ALA ? N/A O00560 N/A
    190 7ft2:D (2.04) BS02 ALA ? N/A O00560 N/A
    191 7ft3:D (2.05) BS02 ALA ? N/A O00560 N/A
    192 7ft4:D (2.17) BS01 ALA ? N/A O00560 N/A
    193 7ft5:D (1.77) BS01 ALA ? N/A O00560 N/A
    194 7ft6:D (1.85) BS02 ALA ? N/A O00560 N/A
    195 7ft7:D (1.78) BS03 ALA ? N/A O00560 N/A
    196 7ft8:D (2.4) BS02 ALA ? N/A O00560 N/A
    197 7ft9:D (1.77) BS01 ALA ? N/A O00560 N/A
    198 7ftc:D (1.87) BS03 ALA ? N/A O00560 N/A
    199 7ftd:D (1.8) BS01 ALA ? N/A O00560 N/A
    200 7lqj:A (2.144) BS01 ALA ? GO:0005886 ... O67854 34002696

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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