1oxr A 1.93 BS01 AIN A 1 L2 G30 Y64 L2 G29 Y63 Y28 G30 G32 H48 D49 Y52 Y68 D94 Y27 G29 G31 H47 D48 Y51 Y67 D93 3.1.1.4 0004623,0005509,0005543,0005576,0006644,0016042,0016787,0046872,0047498,0050482 Kd=0.000000064M -logKd/Ki=5.19, Kd=6.4uM P60045 15823962 141 NLYQFKNMIQCTVPSRSWQDFADYGCYCGKGGSGTPVDDLDRCCQVHDNCYNEAENISGCRPYFKTYSYECTQGTLTCKGDNNACAASVCDCDRLAAICFAGAPYNDANYNIDLKARCN 1tgm A 1.86 BS01 AIN A 1 L2 A18 I19 L2 A17 I18 Y28 G30 G32 H48 D49 Y52 Y73 D99 Y27 G29 G31 H47 D48 Y51 Y64 D89 3.1.1.4 0004623,0005509,0005543,0005576,0006644,0016042,0016787,0035821,0042130,0046872,0047498,0050482,0090729 P59071 202 SLLEFGKMILEETGKLAIPSYSSYGCYCGWGGSGTPKDATDRCCFVHDCCYGNLPDCNPKSDRYKYKRVNGAIVCEKGTSCENRICECDKAAAICFRQNLNTYSKKYMLYPDFLCKGELKC 2qqt A 2.5 BS01 AIN A 1 H109 R255 F381 F422 Q423 P424 H109 R255 F381 F422 Q423 P424 Q105 D108 H109 D110 T184 F186 D188 S190 R255 E258 H351 Q105 D108 H109 D110 T184 F186 D188 S190 R255 E258 H351 1.11.1.7 0004601,0006979,0020037 P80025 596 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 3gcl A 2.5 BS03 AIN A 1 R255 E258 F381 Q423 P424 R255 E258 F381 Q423 P424 Q105 D108 H109 D110 T184 F186 D188 S190 R255 E258 H351 Q105 D108 H109 D110 T184 F186 D188 S190 R255 E258 H351 1.11.1.7 0004601,0006979,0020037 P80025 19465478 609 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 3iaz A 2.0 BS01 AIN A 1 E659 G662 T663 E318 G321 T322 3.4.21.- 0005576 Kd=330uM P24627 20006955 1202 YTRVVWCAVGPEEQKKCQQWSQQSGQNVTCATASTTDDCIVLVLKGEADALNLDGGYIYTAGKCGLVPVLAENRKSSKHSSLDCVLRPTEGYLAVAVVKKANEGLTWNSLKDKKSCHTAVDRTAGWNIPMGLIVNQTGSCAFDEFFSQSCAPGADPKSRLCALCAGDDQGLDKCVPNSKEKYYGYTGAFRCLAEDVGDVAFVKNDTVWENTNGESTADWAKNLKREDFRLLCLDGTRKPVTEAQSCHLAVAPNHAVVSRSDRAAHVEQVLLHQQALFGKNGKNCPDKFCLFKSETKNLLFNDNTECLAKLGGRPTYEEYLGTEYVTAIANLKKCSLEACAF 4nsb A 3.05 BS01 AIN A 1 W10 R14 W269 W331 W10 R14 W268 W330 D115 A117 L119 Y185 D115 A117 L119 Y185 ? 0005576,0005615,0005737,0005783,0005975,0006032,0006915,0006954,0007250,0008061,0009612,0010800,0030246,0030324,0032757,0034612,0045766,0048471,0051897,0070374,0070555,0070741,0071356 Q7YS85 402 YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEWNDVTLYDTLNTLKNRNPNLKTLLSVGGWNYGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLWPGWRDKRHLTTLVKEMKAEFVREAQAGTEQLLLSAAVTAGKIAIDRGYDIAQISRHLDFISLLTYDFHGAWRQTVGHHSPLFRGNEDASSRFSNADYAVSYMLRLGAPANKLVMGIPTFGRSYTLASSKTDVGAPISGPGIPGRFTKWKGILAYYEICDFLHGATTHRFRDQQVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPLTSAIKDVLARV 6mqf A 1.693 BS01 AIN A 1 L2 G30 V31 L2 G29 V30 N28 G30 G32 H48 K49 Y52 Y73 D99 N27 G29 G31 H47 K48 Y51 Y64 D89 ? 0004623,0005509,0005543,0005576,0006644,0016042,0031640,0035821,0042130,0042742,0047498,0050482,0050832,0090729 Q9I834 30679550 202 SLFELGKMILQETGKNPAKSYGVYGCNCGVGGRGKPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLDTYNKKYRYNYLKPFCKKADPC 6mqf B 1.693 BS01 AIN B 1 L2 G30 V31 K49 K69 L2 G29 V30 K48 K60 N28 G30 G32 H48 K49 Y52 Y73 D99 N27 G29 G31 H47 K48 Y51 Y64 D89 ? 0004623,0005509,0005543,0005576,0006644,0016042,0031640,0035821,0042130,0042742,0047498,0050482,0050832,0090729 Q9I834 30679550 203 SLFELGKMILQETGKNPAKSYGVYGCNCGVGGRGKPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLDTYNKKYRYNYLKPFCKKADPC 8j3w A 3.07 BS01 AIN A 1 F324 L363 L367 W995 F316 L355 L359 W915 7.6.2.-,7.6.2.2,7.6.2.3 0001409,0002576,0005515,0005524,0005730,0005794,0005886,0006805,0006855,0006869,0008559,0015132,0015143,0015216,0015431,0015432,0015562,0015721,0015732,0015747,0016020,0016323,0016324,0016404,0016887,0031088,0032310,0034634,0034775,0042626,0042910,0043225,0055085,0060271,0070730,0071716,0098591,0098656,0140115,0140359,0150104,1903790 O15439 1401 KPNPLQDANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSQHLGEELQGFWDKEVLRAENDAQKPSLTRAIIKCYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSYWANKQSMLNTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKESLFYKMVQQLGKAEAAALTETAKQVYFKRNYP