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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 387 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    201 3m82:D (2.4) BS01 ACT 3.1.1.41
    3.1.1.72
    GO:0005509 ... Q9WXT2 22411095
    202 3m82:E (2.4) BS02 ACT 3.1.1.41
    3.1.1.72
    GO:0005509 ... Q9WXT2 22411095
    203 3m82:F (2.4) BS01 ACT 3.1.1.41
    3.1.1.72
    GO:0005509 ... Q9WXT2 22411095
    204 3m83:A (2.12) BS03 ACT 3.1.1.41
    3.1.1.72
    GO:0005509 ... Q9WXT2 22411095
    205 3m83:B (2.12) BS02 ACT 3.1.1.41
    3.1.1.72
    GO:0005509 ... Q9WXT2 22411095
    206 3m83:C (2.12) BS02 ACT 3.1.1.41
    3.1.1.72
    GO:0005509 ... Q9WXT2 22411095
    207 3m83:D (2.12) BS03 ACT 3.1.1.41
    3.1.1.72
    GO:0005509 ... Q9WXT2 22411095
    208 3m83:E (2.12) BS02 ACT 3.1.1.41
    3.1.1.72
    GO:0005509 ... Q9WXT2 22411095
    209 3m83:F (2.12) BS02 ACT 3.1.1.41
    3.1.1.72
    GO:0005509 ... Q9WXT2 22411095
    210 3nh4:A (2.0) BS02 ACT 3.5.1.114 GO:0004046 ... Q91XE4 20921362
    211 3nh5:A (2.094) BS02 ACT 3.5.1.114 GO:0004046 ... Q91XE4 20921362
    212 3pe7:A (1.65) BS04 ACT ? GO:0016829 ... A1JMA5 20851883
    213 3sbm:A (1.35) BS01 ACT 2.3.1.39 GO:0004314 ... Q4U443 21707057
    214 3sbm:A (1.35) BS02 ACT 2.3.1.39 GO:0004314 ... Q4U443 21707057
    215 3sbm:A (1.35) BS03 ACT 2.3.1.39 GO:0004314 ... Q4U443 21707057
    216 3sdn:A (1.5) BS02 ACT 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 21800850
    217 3sfh:A (2.7) BS02 ACT 3.5.1.-
    3.5.1.98
    GO:0000118 ... Q9BY41 21723733
    218 3sfh:A (2.7) BS03 ACT 3.5.1.-
    3.5.1.98
    GO:0000118 ... Q9BY41 21723733
    219 3sfh:A (2.7) BS04 ACT 3.5.1.-
    3.5.1.98
    GO:0000118 ... Q9BY41 21723733
    220 3szz:A (2.0) BS03 ACT 3.6.1.9 GO:0016787 ... Q92UV8 22035792
    221 3vdq:A (2.2) BS01 ACT 1.1.1.30 GO:0000166 ... D0VWQ0 18453685
    222 3vdq:B (2.2) BS01 ACT 1.1.1.30 GO:0000166 ... D0VWQ0 18453685
    223 3vdq:C (2.2) BS01 ACT 1.1.1.30 GO:0000166 ... D0VWQ0 18453685
    224 3vdq:D (2.2) BS01 ACT 1.1.1.30 GO:0000166 ... D0VWQ0 18453685
    225 3vpe:A (1.6) BS03 ACT 3.5.2.6 GO:0008800 ... G5ELM3 23070156
    226 3vpe:A (1.6) BS04 ACT 3.5.2.6 GO:0008800 ... G5ELM3 23070156
    227 4a3u:A (1.7) BS02 ACT ? GO:0000166 ... Q5NLA1 23033175
    228 4a3u:B (1.7) BS02 ACT ? GO:0000166 ... Q5NLA1 23033175
    229 4b6z:A (1.9) BS02 ACT ? GO:0004181 ... B4EEQ5 24531462
    230 4b6z:B (1.9) BS02 ACT ? GO:0004181 ... B4EEQ5 24531462
    231 4b6z:C (1.9) BS02 ACT ? GO:0004181 ... B4EEQ5 24531462
    232 4b6z:D (1.9) BS02 ACT ? GO:0004181 ... B4EEQ5 24531462
    233 4bf7:A (2.001) BS08 ACT 3.2.1.89 GO:0015926 ... Q5B153 23908026
    234 4bf7:A (2.001) BS09 ACT 3.2.1.89 GO:0015926 ... Q5B153 23908026
    235 4bf7:A (2.001) BS10 ACT 3.2.1.89 GO:0015926 ... Q5B153 23908026
    236 4bf7:A (2.001) BS11 ACT 3.2.1.89 GO:0015926 ... Q5B153 23908026
    237 4bf7:A (2.001) BS12 ACT 3.2.1.89 GO:0015926 ... Q5B153 23908026
    238 4bf7:A (2.001) BS13 ACT 3.2.1.89 GO:0015926 ... Q5B153 23908026
    239 4bg8:A (1.96) BS01 ACT ? GO:0000166 ... Q8TX37 24311585
    240 4bg8:B (1.96) BS01 ACT ? GO:0000166 ... Q8TX37 24311585
    241 4bg9:A (1.902) BS01 ACT ? GO:0000166 ... Q8TX37 24311585
    242 4bzw:B (2.148) BS05 ACT 3.1.1.1 GO:0016298 ... F9US10 24127688
    243 4bzz:A (3.0) BS01 ACT 3.1.1.1 GO:0016298 ... F9US10 24127688
    244 4bzz:A (3.0) BS02 ACT 3.1.1.1 GO:0016298 ... F9US10 24127688
    245 4c01:A (2.3) BS01 ACT 3.1.1.1 GO:0016298 ... F9US10 24127688
    246 4c01:B (2.3) BS01 ACT 3.1.1.1 GO:0016298 ... F9US10 24127688
    247 4c01:C (2.3) BS01 ACT 3.1.1.1 GO:0016298 ... F9US10 24127688
    248 4c01:D (2.3) BS01 ACT 3.1.1.1 GO:0016298 ... F9US10 24127688
    249 4c01:E (2.3) BS02 ACT 3.1.1.1 GO:0016298 ... F9US10 24127688
    250 4c01:F (2.3) BS02 ACT 3.1.1.1 GO:0016298 ... F9US10 24127688
    251 4crq:A (1.5) BS03 ACT 3.2.1.39 GO:0004553 ... G0L2L9 25664729
    252 4crq:B (1.5) BS02 ACT 3.2.1.39 GO:0004553 ... G0L2L9 25664729
    253 4dlt:A (1.699) BS05 ACT 3.6.5.2 GO:0003924 ... P01112 22845804
    254 4dlu:A (1.6) BS05 ACT 3.6.5.2 GO:0003924 ... P01112 22845804
    255 4dlw:A (1.72) BS05 ACT 3.6.5.2 GO:0003924 ... P01112 22845804
    256 4eht:A (1.95) BS03 ACT 3.-.-.- GO:0005524 ... Q5U925 22827463
    257 4eht:A (1.95) BS04 ACT 3.-.-.- GO:0005524 ... Q5U925 22827463
    258 4eht:B (1.95) BS03 ACT 3.-.-.- GO:0005524 ... Q5U925 22827463
    259 4ehu:A (1.6) BS03 ACT 3.-.-.- GO:0005524 ... Q5U925 22827463
    260 4eu6:A (1.988) BS02 ACT 2.8.3.18 GO:0003986 ... B3EY95 23030530
    261 4eu6:B (1.988) BS02 ACT 2.8.3.18 GO:0003986 ... B3EY95 23030530
    262 4ewl:A (1.85) BS03 ACT 3.5.1.103 GO:0005886 ... P9WJN3 23090394
    263 4ewl:B (1.85) BS02 ACT 3.5.1.103 GO:0005886 ... P9WJN3 23090394
    264 4jo0:A (2.17) BS04 ACT 1.14.99.65 GO:0005737 ... F2RB80 23980641
    265 4k08:A (2.0) BS01 ACT ? N/A Q2IFX2 23897711
    266 4k0d:B (1.997) BS03 ACT 2.7.13.3 N/A Q2IDQ5 23897711
    267 4ubq:A (2.3) BS03 ACT 3.5.2.6 GO:0008270 ... Q9KVZ2 25744464
    268 4uhd:A (1.07) BS02 ACT 3.1.1.1 GO:0003824 ... A0A0M3KKY6 26011036
    269 4uhd:A (1.07) BS03 ACT 3.1.1.1 GO:0003824 ... A0A0M3KKY6 26011036
    270 4wy9:A (1.4) BS01 ACT ? N/A Q0P8B2 26923153
    271 5bya:A (1.9) BS06 ACT 2.7.4.24 GO:0000829 ... O43314 26153667
    272 5cad:A (1.49) BS02 ACT ? GO:0046872 ... A0A158RFR1 27004988
    273 5d2i:A (1.78) BS03 ACT 4.1.1.77 GO:0003824 ... Q1XGK3 27082660
    274 5d2i:B (1.78) BS02 ACT 4.1.1.77 GO:0003824 ... Q1XGK3 27082660
    275 5d2i:B (1.78) BS03 ACT 4.1.1.77 GO:0003824 ... Q1XGK3 27082660
    276 5d2j:B (1.718) BS02 ACT 4.1.1.77 GO:0003824 ... Q1XGK3 27082660
    277 5d88:A (1.66) BS02 ACT ? GO:0006508 ... Q8TWX5 26627657
    278 5dw4:A (1.622) BS01 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    279 5dw4:A (1.622) BS02 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    280 5dw4:B (1.622) BS01 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    281 5dw4:B (1.622) BS02 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    282 5dw4:B (1.622) BS03 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    283 5dw5:A (1.656) BS02 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    284 5dw5:B (1.656) BS01 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    285 5dw6:A (1.548) BS01 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    286 5dw6:A (1.548) BS03 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    287 5dw6:B (1.548) BS01 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    288 5dw6:B (1.548) BS02 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    289 5dw6:B (1.548) BS03 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    290 5e5h:B (2.052) BS02 ACT 2.8.3.18 GO:0003986 ... B3EY95 27242998
    291 5evo:A (2.51) BS01 ACT 1.8.5.1 GO:0004364 ... U5XYA0 27067046
    292 5g0x:A (1.7) BS02 ACT 3.5.1.- GO:0004407 ... Q9HXM1 27951649
    293 5g0x:C (1.7) BS02 ACT 3.5.1.- GO:0004407 ... Q9HXM1 27951649
    294 5jn8:A (1.85) BS05 ACT 4.2.1.1 GO:0004089 ... P22748 28975383
    295 5jn8:D (1.85) BS05 ACT 4.2.1.1 GO:0004089 ... P22748 28975383
    296 5jn9:D (2.1) BS05 ACT 4.2.1.1 GO:0004089 ... P22748 28975383
    297 5jna:D (2.0) BS05 ACT 4.2.1.1 GO:0004089 ... P22748 28975383
    298 5jnc:D (2.0) BS05 ACT 4.2.1.1 GO:0004089 ... P22748 28975383
    299 5ku6:D (1.8) BS05 ACT 4.2.1.1 GO:0004089 ... P22748 28975383
    300 5m45:A (1.87) BS02 ACT 6.4.1.6 GO:0003824 ... Q8RM03 28775283
    301 5m45:B (1.87) BS03 ACT 6.4.1.6 GO:0005524 ... Q8RM04 28775283
    302 5m45:D (1.87) BS02 ACT 6.4.1.6 GO:0003824 ... Q8RM03 28775283
    303 5m45:E (1.87) BS03 ACT 6.4.1.6 GO:0005524 ... Q8RM04 28775283
    304 5m45:G (1.87) BS02 ACT 6.4.1.6 GO:0003824 ... Q8RM03 28775283
    305 5m45:H (1.87) BS03 ACT 6.4.1.6 GO:0005524 ... Q8RM04 28775283
    306 5m45:J (1.87) BS02 ACT 6.4.1.6 GO:0003824 ... Q8RM03 28775283
    307 5m45:K (1.87) BS03 ACT 6.4.1.6 GO:0005524 ... Q8RM04 28775283
    308 5t4t:A (1.511) BS01 ACT 3.8.1.3 GO:0003824 ... Q6NAM1 28104837
    309 5t4t:B (1.511) BS01 ACT 3.8.1.3 GO:0003824 ... Q6NAM1 28104837
    310 5wid:A (1.681) BS02 ACT ? GO:0000166 ... Q8TPV5 31801875
    311 5ys8:A (2.798) BS01 ACT ? GO:0005886 ... A8ALU5 29588525
    312 5ys8:A (2.798) BS02 ACT ? GO:0005886 ... A8ALU5 29588525
    313 5ys8:B (2.798) BS01 ACT ? GO:0005886 ... A8ALU5 29588525
    314 5ys8:C (2.798) BS01 ACT ? GO:0005886 ... A8ALU5 29588525
    315 5zyr:A (2.20001) BS02 ACT 1.5.1.36 GO:0009056 ... Q6Q271 N/A
    316 5zyr:B (2.20001) BS02 ACT 1.5.1.36 GO:0009056 ... Q6Q271 N/A
    317 6a2f:A (2.5) BS03 ACT 5.1.1.1 GO:0003824 ... Q9HUN4 29964014
    318 6a2f:A (2.5) BS04 ACT 5.1.1.1 GO:0003824 ... Q9HUN4 29964014
    319 6a2f:B (2.5) BS03 ACT 5.1.1.1 GO:0003824 ... Q9HUN4 29964014
    320 6bww:A (2.1) BS04 ACT 1.14.14.1 GO:0004497 ... P00178 29730233
    321 6bww:A (2.1) BS05 ACT 1.14.14.1 GO:0004497 ... P00178 29730233
    322 6bww:A (2.1) BS06 ACT 1.14.14.1 GO:0004497 ... P00178 29730233
    323 6bww:A (2.1) BS07 ACT 1.14.14.1 GO:0004497 ... P00178 29730233
    324 6bww:A (2.1) BS08 ACT 1.14.14.1 GO:0004497 ... P00178 29730233
    325 6bww:A (2.1) BS09 ACT 1.14.14.1 GO:0004497 ... P00178 29730233
    326 6bww:A (2.1) BS10 ACT 1.14.14.1 GO:0004497 ... P00178 29730233
    327 6eb0:C (2.37) BS01 ACT ? GO:0004497 ... A0A140NG21 31068633
    328 6hxi:B (2.1) BS02 ACT 6.2.1.5 GO:0003824 ... A0A1V4VDZ9 30944476
    329 6kfa:A (1.5) BS01 ACT ? GO:0016829 ... A0A0H5BR52 32679618
    330 6km8:A (3.099) BS02 ACT N/A N/A N/A 31980708
    331 6pi8:A (1.635) BS01 ACT ? GO:0004407 ... A0A0J7JFD7 31436969
    332 6pi8:B (1.635) BS01 ACT ? GO:0004407 ... A0A0J7JFD7 31436969
    333 6su4:A (1.5) BS01 ACT ? GO:0016020 ... A0A2R4S913 32034096
    334 6su4:X (1.5) BS01 ACT ? GO:0016020 ... A0A2R4S913 32034096
    335 6uqw:A (1.65) BS01 ACT 3.1.-.- GO:0004104 ... Q9HUP2 32371400
    336 6uqw:B (1.65) BS01 ACT 3.1.-.- GO:0004104 ... Q9HUP2 32371400
    337 6uqz:A (1.43) BS01 ACT 3.1.-.- GO:0004104 ... Q9HUP2 32371400
    338 6uqz:B (1.43) BS01 ACT 3.1.-.- GO:0004104 ... Q9HUP2 32371400
    339 6ur1:A (1.42) BS01 ACT ? GO:0004104 ... Q9HUP2 32371400
    340 6ur1:B (1.42) BS01 ACT ? GO:0004104 ... Q9HUP2 32371400
    341 6v2l:A (1.7) BS02 ACT 4.1.1.49 GO:0000287 ... P22259 31911238
    342 6v2n:A (1.65) BS02 ACT 4.1.1.49 GO:0000287 ... P22259 31911238
    343 6xab:A (1.781) BS01 ACT N/A GO:0043190 ... N/A 33538578
    344 6xw0:AAA (1.8) BS01 ACT 4.6.1.18 GO:0003676 ... P61823 32022076
    345 6xw0:AAA (1.8) BS02 ACT 4.6.1.18 GO:0003676 ... P61823 32022076
    346 6xw0:BBB (1.8) BS01 ACT 4.6.1.18 GO:0003676 ... P61823 32022076
    347 7bdz:AAA (1.94) BS01 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    348 7bdz:AAA (1.94) BS02 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    349 7bdz:AAA (1.94) BS03 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    350 7bdz:AAA (1.94) BS04 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    351 7bdz:AAA (1.94) BS05 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    352 7be0:AAA (1.62) BS01 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    353 7be0:AAA (1.62) BS02 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    354 7be0:AAA (1.62) BS03 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    355 7be0:AAA (1.62) BS04 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    356 7be0:AAA (1.62) BS05 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    357 7be0:AAA (1.62) BS06 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    358 7be1:AAA (1.4) BS02 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    359 7be1:AAA (1.4) BS03 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    360 7be1:AAA (1.4) BS04 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    361 7beb:AAA (1.32) BS02 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    362 7beb:AAA (1.32) BS03 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    363 7beb:AAA (1.32) BS04 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    364 7bec:AAA (1.74) BS02 ACT 3.2.1.17 GO:0003796 ... P00698 33540880
    365 7c4d:A (2.03) BS01 ACT ? GO:0016787 ... A0A2S1GUX0 33445864
    366 7coi:A (1.8) BS01 ACT 4.2.1.1 GO:0004089 ... Q4WQ18 32975213
    367 7coi:B (1.8) BS01 ACT 4.2.1.1 GO:0004089 ... Q4WQ18 32975213
    368 7coi:C (1.8) BS01 ACT 4.2.1.1 GO:0004089 ... Q4WQ18 32975213
    369 7coi:D (1.8) BS01 ACT 4.2.1.1 GO:0004089 ... Q4WQ18 32975213
    370 7e43:A (2.2) BS01 ACT 1.8.4.11
    1.8.4.12
    GO:0006979 ... O25011 33807684
    371 7e43:A (2.2) BS02 ACT 1.8.4.11
    1.8.4.12
    GO:0006979 ... O25011 33807684
    372 7e43:B (2.2) BS01 ACT 1.8.4.11
    1.8.4.12
    GO:0006979 ... O25011 33807684
    373 7e43:B (2.2) BS02 ACT 1.8.4.11
    1.8.4.12
    GO:0006979 ... O25011 33807684
    374 7kuv:A (2.15) BS01 ACT 3.5.1.48
    3.5.1.62
    GO:0005634 ... F1QCV2 33449614
    375 7toi:A (1.13) BS01 ACT ? GO:0016787 ... A0A5M4AV20 35566004
    376 7xll:A (1.76) BS01 ACT 5.1.1.1 GO:0003824 ... N/A 36732053
    377 7xll:A (1.76) BS02 ACT 5.1.1.1 GO:0003824 ... N/A 36732053
    378 7xll:A (1.76) BS03 ACT 5.1.1.1 GO:0003824 ... N/A 36732053
    379 7xll:B (1.76) BS02 ACT 5.1.1.1 GO:0003824 ... N/A 36732053
    380 7xll:B (1.76) BS03 ACT 5.1.1.1 GO:0003824 ... N/A 36732053
    381 7yqs:A (1.25) BS04 ACT ? GO:0016829 ... A0A8D5PZ14 38382672
    382 8bqm:AAA (1.17) BS01 ACT 3.2.1.17 GO:0003796 ... P00698 36597851
    383 8fff:A (1.92) BS01 ACT 6.3.2.4 GO:0003824 ... W8TRT0 38293037
    384 8fff:A (1.92) BS02 ACT 6.3.2.4 GO:0003824 ... W8TRT0 38293037
    385 8i4d:A (1.06) BS04 ACT 4.2.2.- GO:0046872 ... A0A8J0PCK3 38382672
    386 8y7g:A (3.15) BS03 ACT N/A N/A A0A0H2SHM8 38967023
    387 8y7g:B (3.15) BS03 ACT N/A N/A A0A0H2SHM8 38967023

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218