5os5 A 1.74 BS03 A8K A 1 E175 L178 R179 V182 E183 Y199 V206 E51 L54 R55 V58 E59 Y75 V82 D256 K258 E260 N261 D274 T292 D132 K134 E136 N137 D150 T168 2.7.11.1 0004672,0005524,0006468 Kd=410uM -logKd/Ki=3.39, Kd=410uM O14965 29045126 404 KRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN 5z4h A 2.0 BS01 A8K A 1 N46 A47 Q72 D73 I78 A91 I94 M95 T165 V167 N31 A32 Q57 D58 I63 A76 I79 M80 T133 V135 5.6.2.2 0003677,0003918,0005524,0006265 -logKd/Ki=3.02, IC50=0.95mM P0AES6 30429968 303 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY 5z4h B 2.0 BS02 A8K B 1 V43 N46 A47 Q72 D73 I78 A91 I94 M95 V120 T165 V167 V28 N31 A32 Q57 D58 I63 A76 I79 M80 V89 T134 V136 5.6.2.2 0003677,0003918,0005524,0006265 P0AES6 30429968 303 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGG