1fww A 1.85 BS02 A5P A 1 N1048 R1049 S1050 H1185 S1197 D1233 N47 R48 S49 H184 S196 D232 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 O66496 19228070 1269 EKFLVIAGPCAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDASTQLPLSQLEGIIEAILEIREVASKYYETI 1fxq A 1.8 BS02 A5P A 1 N1048 R1049 S1050 H1185 S1197 D1233 N47 R48 S49 H184 S196 D232 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 O66496 11115499 1269 EKFLVIAGPCAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDASTQLPLSQLEGIIEAILEIREVASKYYETI 1fxq B 1.8 BS02 A5P B 1 K2046 N2048 R2049 S2050 K2196 S2197 D2233 K44 N46 R47 S48 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 O66496 11115499 2269 KFLVIAGPCAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDASTQLPLSQLEGIIEAILEIREVASKYYETI 1fy6 A 1.89 BS02 A5P A 1 N1048 R1049 S1050 H1185 D1233 N47 R48 S49 H184 D227 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 O66496 11115499 1269 EKFLVIAGPCAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDASTQLPLSQLEGIIEAILEIREVASKYYETI 1lrq A 1.8 BS02 A5P A 1 N1048 R1049 S1050 Q1188 K1196 S1197 D1233 N47 R48 S49 Q187 K195 S196 D232 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 O66496 12441100 1269 EKFLVIAGPCAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATGSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDASTQLPLSQLEGIIEAILEIREVASKYYETI 1t8x A 1.8 BS02 A5P A 1 N1048 R1049 S1050 D1233 N47 R48 S49 D226 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 O66496 1269 EKFLVIAGPCAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCGQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDASTQLPLSQLEGIIEAILEIREVASKYYETI 1uj6 A 1.74 BS01 A5P A 1 T30 S32 T33 G87 D89 K99 G100 G102 A104 E108 K126 T28 S30 T31 G85 D87 K97 G98 G100 A102 E106 K124 5.3.1.6 0004751,0006098,0009052,0016853 Ki=0.89mM -logKd/Ki=3.05, Ki=0.89mM Q72J47 13679361 228 RPLESYKKEAAHAAIAYVQDGMVVGLGTGSTARYAVLELARRLREGELKGVVGVPTSRATEELAKREGIPLVDLPPEGVDLAIDGADEIAPGLALIKGMGGALLREKIVERVAKEFIVIADHTKKVPVLGRGPVPVEIVPFGYRATLKAIADLGGEPELRMDGDEFYFTDGGHLIADCRFGPIGDPLGLHRALLEIPGVVETGLFVGMATRALVAGPFGVEELLP 2a2i A 1.95 BS03 A5P A 1 N1048 R1049 S1050 H1185 S1197 D1233 N47 R48 S49 H184 S196 D232 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=0.04uM O66496 19228070 1269 EKFLVIAGPCAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDASTQLPLSQLEGIIEAILEIREVASKYYETI 2a2i B 1.95 BS03 A5P B 1 N2048 R2049 S2050 H2185 D2233 N46 R47 S48 H183 D224 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=0.04uM O66496 19228070 2269 KFLVIAGPCAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDASTQLPLSQLEGIIEAILEIREVASKYYETI 2cxp A 1.7 BS01 A5P A 1 I157 G159 S210 K211 T212 T215 Q354 E358 K519 I157 G159 S210 K211 T212 T215 Q354 E358 K519 K211 E217 G272 R273 E358 H389 K519 K211 E217 G272 R273 E358 H389 K519 5.3.1.9 0001701,0001707,0002639,0004347,0005125,0005515,0005576,0005615,0005737,0005829,0005886,0006002,0006094,0006096,0007165,0007611,0008083,0010595,0016853,0031625,0032355,0032570,0033574,0034101,0035902,0035994,0042593,0043209,0043524,0046686,0048029,0051156,0060170,0061620,0061621,0097367,0141199,1901135 P06745 16375918 1601 MAALTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLNTNHGHILVDYSKNLVSKEVMQMLVELAKSRGVEAARDNMFSGSKINYTEDRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAGKSPEDLEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSAVTSHDSSTNGLISFIKQQRDTKL 2cxp B 1.7 BS01 A5P B 1 I157 G159 S210 K211 T212 T215 Q354 E358 I157 G159 S210 K211 T212 T215 Q354 E358 K211 E217 G272 R273 E358 H389 K519 K211 E217 G272 R273 E358 H389 K519 5.3.1.9 0001701,0001707,0002639,0004347,0005125,0005515,0005576,0005615,0005737,0005829,0005886,0006002,0006094,0006096,0007165,0007611,0008083,0010595,0016853,0031625,0032355,0032570,0033574,0034101,0035902,0035994,0042593,0043209,0043524,0046686,0048029,0051156,0060170,0061620,0061621,0097367,0141199,1901135 P06745 16375918 2601 MAALTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLNTNHGHILVDYSKNLVSKEVMQMLVELAKSRGVEAARDNMFSGSKINYTEDRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAGKSPEDLEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSAVTSHDSSTNGLISFIKQQRDTKL 2ef9 A 2.0 BS02 A5P A 1 K46 N48 R49 S50 Q188 S197 D233 K45 N47 R48 S49 Q187 S196 D232 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=14.18uM O66496 17381075 1269 EKFLVIAGMNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2ef9 B 2.0 BS02 A5P B 1 N48 R49 S50 K196 S197 D233 N46 R47 S48 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=14.18uM O66496 17381075 2269 KFLVIAGMNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2nws A 1.8 BS02 A5P A 1 N1048 R1049 S1050 K1196 S1197 D1233 N47 R48 S49 K195 S196 D232 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=5.44uM O66496 17381075 1269 EKFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDASTQLPLSQLEGIIEAILEIREVASKYYETI 2nws B 1.8 BS02 A5P B 1 K2046 N2048 R2049 S2050 K2196 S2197 D2233 K44 N46 R47 S48 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=5.44uM O66496 17381075 2269 KFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDASTQLPLSQLEGIIEAILEIREVASKYYETI 2nx3 A 2.1 BS02 A5P A 1 K46 N48 R49 S50 Q188 K196 S197 D233 K44 N46 R47 S48 Q186 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=17uM O66496 17381075 269 KFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2nx3 B 2.1 BS02 A5P B 1 N11 K46 N48 R49 S50 H185 Q188 K196 S197 D233 N9 K44 N46 R47 S48 H183 Q186 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=17uM O66496 17381075 269 KFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2nx3 C 2.1 BS02 A5P C 1 K46 N48 R49 S50 H185 S197 D233 K44 N46 R47 S48 H183 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=17uM O66496 17381075 269 KFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2nx3 E 2.1 BS02 A5P E 1 K46 N48 R49 S50 H185 Q188 K196 S197 D233 K44 N46 R47 S48 H183 Q186 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=17uM O66496 17381075 269 KFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2nx3 F 2.1 BS02 A5P F 1 N48 R49 S50 H185 K196 S197 D233 N46 R47 S48 H183 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=17uM O66496 17381075 269 KFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2nx3 G 2.1 BS02 A5P G 1 N11 K46 N48 R49 S50 H185 K196 S197 D233 N9 K44 N46 R47 S48 H183 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=17uM O66496 17381075 269 KFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2nx3 H 2.1 BS02 A5P H 1 N11 K46 N48 R49 S50 H185 K196 S197 D233 N9 K44 N46 R47 S48 H183 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=17uM O66496 17381075 269 KFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2nx3 I 2.1 BS02 A5P I 1 N11 K46 N48 R49 S50 H185 K196 S197 D233 N9 K44 N46 R47 S48 H183 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=17uM O66496 17381075 269 KFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2nx3 J 2.1 BS02 A5P J 1 N11 K46 N48 R49 S50 H185 Q188 K196 S197 D233 N9 K44 N46 R47 S48 H183 Q186 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=17uM O66496 17381075 269 KFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2nx3 K 2.1 BS02 A5P K 1 N48 R49 S50 H185 K196 S197 D233 N46 R47 S48 H183 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=17uM O66496 17381075 269 KFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2nx3 L 2.1 BS02 A5P L 1 N11 K46 N48 R49 S50 H185 Q188 K196 S197 D233 N9 K44 N46 R47 S48 H183 Q186 K194 S195 D231 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=17uM O66496 17381075 269 KFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 2nxg A 1.95 BS02 A5P A 1 K1046 N1048 R1049 S1050 Q1188 S1197 D1233 K45 N47 R48 S49 Q187 S196 D232 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294,0046364 Kd=17uM O66496 17381075 1269 EKFLVIAGPNAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTKNVVEKLKFGGAKEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPGGLGDKSGGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDAPTALPLSQLEGIIEAILEIREVASKYYETI 3tmq A 2.1 BS01 A5P A 1 K58 N60 R61 S62 H200 R205 A211 S212 D248 K58 N60 R61 S62 H200 R205 A211 S212 D248 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294 Q3JP68 23382856 282 MNVAISPGVTAGNSLPFVLFGGINVLESLDFTLDVCGEYVAVTRKLGIPFVFKASFDKANRSSIHSYRGVGLDEGLKIFAEVKARFGVPVITDVHEAEQAAPVAEIADVLQVPAFLARQTDLVVAIAKAGKPVNVKKPQFMSPTQLKHVVSKCGEVGNDRVMLCERGSSFGYDNLVVDMLGFRQMAETTGGCPVIFDVTHSLQCRDPLGDASGGRRRQVLDLARAGIAVGIAGLFLEAHPDPDRARCDGPSALPLHQLEGLLSQMKAIDDLVKRMPALEI 3tmq C 2.1 BS01 A5P C 1 K58 N60 R61 S62 H200 R205 A211 S212 C247 D248 K59 N61 R62 S63 H201 R206 A212 S213 C248 D249 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294 Q3JP68 23382856 282 SMNVAISPGVTAGNSLPFVLFGGINVLESLDFTLDVCGEYVAVTRKLGIPFVFKASFDKANRSSIHSYRGVGLDEGLKIFAEVKARFGVPVITDVHEAEQAAPVAEIADVLQVPAFLARQTDLVVAIAKAGKPVNVKKPQFMSPTQLKHVVSKCGEVGNDRVMLCERGSSFGYDNLVVDMLGFRQMAETTGGCPVIFDVTHSLQCRDPLGDASGGRRRQVLDLARAGIAVGIAGLFLEAHPDPDRARCDGPSALPLHQLEGLLSQMKAIDDLVKRMPALEI 3und A 2.1 BS01 A5P A 1 K58 N60 R61 S62 H200 Q203 R205 A211 S212 D248 K60 N62 R63 S64 H202 Q205 R207 A213 S214 D250 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294 Q3JP68 23382856 301 GSMNVAISPGVTAGNSLPFVLFGGINVLESLDFTLDVCGEYVAVTRKLGIPFVFKASFDKANRSSIHSYRGVGLDEGLKIFAEVKARFGVPVITDVHEAEQAAPVAEIADVLQVPAFLARQTDLVVAIAKAGKPVNVKKPQFMSPTQLKHVVSKCGEVGNDRVMLCERGSSFGYDNLVVDMLGFRQMAETTGGCPVIFDVTHSLQCRDPLGDASGGRRRQVLDLARAGIAVGIAGLFLEAHPDPDRARCDGPSALPLHQLEGLLSQMKAIDDLVKRMPALEIR 3und B 2.1 BS01 A5P B 1 N24 K58 N60 R61 S62 H200 Q203 R205 A211 S212 C247 D248 N27 K61 N63 R64 S65 H203 Q206 R208 A214 S215 C250 D251 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294 Q3JP68 23382856 301 PGSMNVAISPGVTAGNSLPFVLFGGINVLESLDFTLDVCGEYVAVTRKLGIPFVFKASFDKANRSSIHSYRGVGLDEGLKIFAEVKARFGVPVITDVHEAEQAAPVAEIADVLQVPAFLARQTDLVVAIAKAGKPVNVKKPQFMSPTQLKHVVSKCGEVGNDRVMLCERGSSFGYDNLVVDMLGFRQMAETTGGCPVIFDVTHSLQCRDPLGDASGGRRRQVLDLARAGIAVGIAGLFLEAHPDPDRARCDGPSALPLHQLEGLLSQMKAIDDLVKRMPALEIR 3und C 2.1 BS01 A5P C 1 K58 N60 R61 S62 H200 Q203 R205 A211 S212 D248 K59 N61 R62 S63 H201 Q204 R206 A212 S213 D249 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294 Q3JP68 23382856 301 SMNVAISPGVTAGNSLPFVLFGGINVLESLDFTLDVCGEYVAVTRKLGIPFVFKASFDKANRSSIHSYRGVGLDEGLKIFAEVKARFGVPVITDVHEAEQAAPVAEIADVLQVPAFLARQTDLVVAIAKAGKPVNVKKPQFMSPTQLKHVVSKCGEVGNDRVMLCERGSSFGYDNLVVDMLGFRQMAETTGGCPVIFDVTHSLQCRDPLGDASGGRRRQVLDLARAGIAVGIAGLFLEAHPDPDRARCDGPSALPLHQLEGLLSQMKAIDDLVKRMPALEIR 3und D 2.1 BS01 A5P D 1 N24 K58 N60 R61 S62 H200 Q203 R205 A211 S212 C247 D248 N27 K61 N63 R64 S65 H203 Q206 R208 A214 S215 C250 D251 2.5.1.55 0005737,0005829,0008676,0009058,0009103,0016740,0019294 Q3JP68 23382856 301 PGSMNVAISPGVTAGNSLPFVLFGGINVLESLDFTLDVCGEYVAVTRKLGIPFVFKASFDKANRSSIHSYRGVGLDEGLKIFAEVKARFGVPVITDVHEAEQAAPVAEIADVLQVPAFLARQTDLVVAIAKAGKPVNVKKPQFMSPTQLKHVVSKCGEVGNDRVMLCERGSSFGYDNLVVDMLGFRQMAETTGGCPVIFDVTHSLQCRDPLGDASGGRRRQVLDLARAGIAVGIAGLFLEAHPDPDRARCDGPSALPLHQLEGLLSQMKAIDDLVKRMPALEIR 3upb A 1.5 BS01 A5P A 1 D18 N36 K135 F181 R184 S230 R232 D18 N36 K135 F181 R184 S230 R232 D18 E99 K135 T159 F181 D18 E99 K135 T159 F181 2.2.1.2 0004801,0005737,0005975,0006098,0009052,0016740 Q5NFX0 24510200 1601 MQKSVLEQLKQVTMVVADTGDFELIKKYKPVDATTNPSLILKAVKEQKYSNLVAETISKVKANNPDLNSDDLVKEIAIEILVSFGIKILDVIEGKVSSEVDARVSFNSATTIDYAKRIIARYESNGIPKDRVLIKIAATWEGIKAAKLLQKEGINCNLTLIFDKAQAKACAEAGVYLVSPFVGRITDWQMQQNNLKTFPAIADDDGVNSVKAIYKLYKSHGFKTIVMGASFRNVEQVIALAGCDALTISPVLLEELKNRDEHLEVKLTQISEADFRWLMNENAMATHKLAEGIRLFTKDTIELENIIKQNL 3upb B 1.5 BS01 A5P B 1 D18 N36 K135 F181 R184 S230 R232 D16 N34 K133 F179 R182 S228 R230 D18 E99 K135 T159 F181 D16 E97 K133 T157 F179 2.2.1.2 0004801,0005737,0005975,0006098,0009052,0016740 Q5NFX0 24510200 1601 KSVLEQLKQVTMVVADTGDFELIKKYKPVDATTNPSLILKAVKEQKYSNLVAETISKVKANNPDLNSDDLVKEIAIEILVSFGIKILDVIEGKVSSEVDARVSFNSATTIDYAKRIIARYESNGIPKDRVLIKIAATWEGIKAAKLLQKEGINCNLTLIFDKAQAKACAEAGVYLVSPFVGRITDWQMQQNNLKTFPAIADDDGVNSVKAIYKLYKSHGFKTIVMGASFRNVEQVIALAGCDALTISPVLLEELKNRDEHLEVKLTQISEADFRWLMNENAMATHKLAEGIRLFTKDTIELENIIKQNL 5uqi A 1.62 BS01 A5P A 1 G52 K53 S54 S98 N99 S100 T103 P154 G52 K53 S54 S98 N99 S100 T103 P154 ? 0016853,0097367,1901135 A0A0H2VCL5 201 MNNTDLIHLIKHFMHNELKAVEEVIDSPLSEFANLIKVLQSCQGKVVFIGVGKSGIIARKLAATFASTGTPSFFVHGTEAVHGDLGMVAKDDVVILISNSGETAEILATLPSLKKMGNYLISFTRSHHSSLAISCDLSVEIPVKSEADNLGLAPSCSSTVVLVVGDAVALALSELKKFTRADFGLYHP