5zz4 A 2.9 BS01 9M3 A 1 L408 G411 Q412 A428 K430 Y476 M477 N479 G480 D521 N526 L528 L542 S543 Y551 L14 G17 Q18 A34 K36 Y82 M83 N85 G86 D127 N132 L134 L148 S149 Y157 D521 R525 N526 D539 D127 R131 N132 D145 2.7.10.2 0004672,0004713,0005524,0006468 -logKd/Ki=9.17, IC50=0.67nM IC50=0.670000nM Q06187 30216722 701 WEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVM 5zz4 B 2.9 BS01 9M3 B 1 L408 G411 Q412 V416 A428 K430 Y476 M477 A478 G480 N526 L528 D539 L542 S543 Y551 L16 G19 Q20 V24 A36 K38 Y84 M85 A86 G88 N134 L136 D147 L150 S151 Y159 D521 R525 N526 D539 D129 R133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 IC50=0.670000nM Q06187 30216722 701 GSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVM 5zz4 C 2.9 BS01 9M3 C 1 L408 G411 V416 A428 K430 Y476 M477 G480 N526 L528 D539 L542 L15 G18 V23 A35 K37 Y83 M84 G87 N133 L135 D146 L149 D521 R525 N526 D539 D128 R132 N133 D146 2.7.10.2 0004672,0004713,0005524,0006468 IC50=0.670000nM Q06187 30216722 701 SWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVM 5zz4 D 2.9 BS01 9M3 D 1 L408 G411 Q412 V416 A428 K430 Y476 M477 A478 G480 D521 L528 D539 S543 L16 G19 Q20 V24 A36 K38 Y84 M85 A86 G88 D129 L136 D147 S151 D521 R525 N526 D539 D129 R133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 IC50=0.670000nM Q06187 30216722 701 GSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVM 5zz4 E 2.9 BS01 9M3 E 1 L408 G411 Q412 V416 A428 K430 Y476 M477 N526 L528 D539 L542 Y551 L15 G18 Q19 V23 A35 K37 Y83 M84 N133 L135 D146 L149 Y158 D521 R525 N526 D539 D128 R132 N133 D146 2.7.10.2 0004672,0004713,0005524,0006468 IC50=0.670000nM Q06187 30216722 701 SWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVM 5zz4 F 2.9 BS01 9M3 F 1 L408 G411 Q412 V416 A428 K430 Y476 M477 A478 G480 L528 D539 L16 G19 Q20 V24 A36 K38 Y84 M85 A86 G88 L136 D147 D521 R525 N526 D539 D129 R133 N134 D147 2.7.10.2 0004672,0004713,0005524,0006468 IC50=0.670000nM Q06187 30216722 701 GSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVM