2of4 A 2.7 BS01 979 A 1 L251 V259 A271 Y318 M319 G322 A368 L371 L21 V29 A41 Y88 M89 G92 A138 L141 D364 R366 A368 N369 D382 A400 F402 D134 R136 A138 N139 D152 A170 F172 2.7.10.2 0004672,0004713,0005524,0006468 -logKd/Ki=7.09, IC50=81nM IC50=81nM P06239 17276681 101 KPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTAT