3b8q A 2.75 BS01 900 A 1 L840 V848 A866 K868 E885 L889 T916 C919 L1035 C1045 D1046 F1047 L23 V31 A49 K51 E68 L72 T99 C102 L168 C178 D179 F180 D1028 A1030 R1032 N1033 D1046 D161 A163 R165 N166 D179 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169 -logKd/Ki=9.30, IC50=0.5nM IC50=0.480000nM P35968 18324761 501 ERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAPEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH 3b8q B 2.75 BS01 900 B 1 L840 V848 A866 K868 E885 L889 T916 C919 G922 L1035 C1045 D1046 L21 V27 A45 K47 E64 L68 T95 C98 G101 L158 C168 D169 D1028 A1030 R1032 N1033 D1046 D151 A153 R155 N156 D169 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169 IC50=0.480000nM P35968 18324761 502 LPYDASKWEFPRDRLKLGKPLGRGGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQA