5nhh A 1.94 BS01 8XH A 1 I31 G37 V39 A52 K54 M108 T110 K114 L156 D167 I21 G27 V29 A42 K44 M98 T100 K104 L146 D157 D149 K151 S153 N154 D167 T190 D139 K141 S143 N144 D157 T180 2.7.11.24 0000165,0001784,0003677,0004672,0004674,0004707,0005515,0005524,0005576,0005634,0005654,0005737,0005739,0005769,0005770,0005788,0005794,0005813,0005819,0005829,0005856,0005886,0005901,0005925,0006357,0006468,0006915,0006935,0006974,0007165,0007166,0007268,0007507,0007611,0008286,0008353,0009887,0010759,0010800,0014032,0014044,0016020,0016301,0016310,0018105,0018107,0019858,0019902,0030278,0030521,0030641,0030878,0031143,0031647,0031663,0032206,0032496,0032872,0033554,0033598,0034198,0035094,0035556,0035578,0038127,0038133,0042473,0042552,0042802,0043330,0043401,0045202,0045542,0045596,0048009,0048538,0050847,0050852,0050853,0051403,0051493,0060020,0060291,0060324,0060425,0060440,0060716,0061308,0070161,0070371,0070849,0071356,0072584,0072686,0090170,0106310,0120041,1904813,2000641 ic50<0.00113uM -logKd/Ki=8.95, IC50<1.13nM IC50=4.8nM P28482 28376306 404 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGY