5neb A 2.05 BS01 8VE A 1 Y61 P88 T90 R95 G140 S141 T142 E190 Y61 P88 T90 R95 G140 S141 T142 E190 ? 0015276,0016020 Ki=17nM -logKd/Ki=7.77, Ki=17nM P22756 28691798 307 GANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGC 5neb B 2.05 BS01 8VE B 1 Y61 P88 T90 R95 G140 S141 T142 E190 Y61 P88 T90 R95 G140 S141 T142 E190 ? 0015276,0016020 Ki=17nM P22756 28691798 309 GANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWW 5nih A 1.3 BS01 8VE A 1 E13 Y61 P89 T91 R96 L138 G141 S142 T143 E193 M196 E13 Y61 P89 T91 R96 L138 G141 S142 T143 E193 M196 ? 0015276,0016020 Ki=134nM -logKd/Ki=6.87, Ki=134nM P19491 28691798 304 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECG 5nih B 1.3 BS01 8VE B 1 E13 Y61 P89 T91 R96 L138 G141 S142 T143 E193 M196 E10 Y58 P86 T88 R93 L135 G138 S139 T140 E190 M193 ? 0015276,0016020 Ki=134nM P19491 28691798 303 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGS 5o4f A 2.1 BS02 8VE A 1 Y61 P88 T90 R95 A141 T142 E189 Y58 P85 T87 R92 A136 T137 E184 ? 0015276,0016020 Ki=208uM P42264 28691798 302 RSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGCP 5o4f B 2.1 BS01 8VE B 1 Y61 P88 T90 R95 A141 T142 E189 Y58 P85 T87 R92 A138 T139 E186 ? 0015276,0016020 Ki=208uM -logKd/Ki=6.68, Ki=208nM P42264 28691798 305 RSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGC